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Chryssostomos Chatgilialoglu

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Chryssostomos Chatgilialoglu; Carla Ferreri; Annalisa Masi; Michele Melchiorre; Anna Sansone; Michael A Terzidis; Armida Torreggiani
Free radicals in chemical biology: from chemical behavior to biomarker development.
Carla Ferreri; Chryssostomos Chatgilialoglu
Role of fatty acid-based functional lipidomics in the development of molecular diagnostic tools.
H Souabni; V Thoma; Athanassia Siafaka-Kapadai; Laura Baciou; T Bizouarn; Chryssostomos Chatgilialoglu; Carla Ferreri; Chantal Houée-Levin; M A Ostuni
trans Arachidonic acid isomers inhibit NADPH-oxidase activity by direct interaction with enzyme components.

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All Publications

2013: Chryssostomos Chatgilialoglu; Carla Ferreri; Annalisa Masi; Michele Melchiorre; Anna Sansone; Michael A Terzidis; Armida Torreggiani
Free radicals in chemical biology: from chemical behavior to biomarker development.
Journal of visualized experiments : JoVE 2013;(74):.
2012: Carla Ferreri; Chryssostomos Chatgilialoglu
Role of fatty acid-based functional lipidomics in the development of molecular diagnostic tools.
Expert review of molecular diagnostics 2012;12(7):767-80.
2012: H Souabni; V Thoma; Athanassia Siafaka-Kapadai; Laura Baciou; T Bizouarn; Chryssostomos Chatgilialoglu; Carla Ferreri; Chantal Houée-Levin; M A Ostuni
trans Arachidonic acid isomers inhibit NADPH-oxidase activity by direct interaction with enzyme components.
Biochimica et biophysica acta 2012;1818(9):2314-24.
2012: Chryssostomos Chatgilialoglu; Stéphane Gastaldi; Gabriel Kciuk; Olivier Mozziconacci; Maurizio Tamba; Michèle P Bertrand; Krzysztof Bobrowski; Vitaliy I Timokhin
Kinetic studies on the formation of sulfonyl radicals and their addition to carbon-carbon multiple bonds.
The journal of physical chemistry. A 2012;116(29):7623-8.
2012: Carla Ferreri; Gilles Fouret; Stanislav A Grabovskiy; Natalia Kabal'nova; Michele Melchiorre; Manar Aoun; Charles Coudray; Christine Feillet-Coudray; Chryssostomos Chatgilialoglu
Trans fatty acids: chemical synthesis of eicosapentaenoic acid isomers and detection in rats fed a deodorized fish oil diet.
Chemical research in toxicology 2012;25(3):687-94.
2012: Manar Aoun; Marie-Annette Carbonneau; Béatrice Chabi; Chryssostomos Chatgilialoglu; Jean Paul Cristol; David Crouzier; Christine Feillet-Coudray; Carla Ferreri; Gilles Fouret; Chantal Wrutniak-Cabello; Charles Coudray
Rat liver mitochondrial membrane characteristics and mitochondrial functions are more profoundly altered by dietary lipid quantity than by dietary lipid quality: effect of different nutritional lipid patterns.
The British journal of nutrition 2012;107(5):647-59.
2012: Chryssostomos Chatgilialoglu; Carla Ferreri; Annalisa Masi; Michele Melchiorre; Anna Sansone; Michael A Terzidis; Armida Torreggiani
Biomimetic models of radical stress and related biomarkers.
Chimia 2012;66(6):368-71.
2012: Chryssostomos Chatgilialoglu; Jacques Lalevée
Recent applications of the (TMS)3SiH radical-based reagent.
Molecules (Basel, Switzerland) 2012;17(1):527-55.
2011: Guy Cohen; Carla Ferreri; Michel Guichardant; Nurit Kaiser; Yael Riahi; Chryssostomos Chatgilialoglu; Ofer Shamni; Shlomo Sasson
Role of lipid peroxidation and PPAR-δ in amplifying glucose-stimulated insulin secretion.
Diabetes 2011;60(11):2830-42.
2011: Chryssostomos Chatgilialoglu; Carla Ferreri; Giovanni Renzone; Anna Maria Salzano; Armida Torreggiani; Andrea Scaloni
Radiation-induced reductive modifications of sulfur-containing amino acids within peptides and proteins.
Journal of proteomics 2011;74(11):2264-73.
2011: Michele Melchiorre; Armida Torreggiani; Chryssostomos Chatgilialoglu; Carla Ferreri
Lipid markers of "geometrical" radical stress: synthesis of monotrans cholesteryl ester isomers and detection in human plasma.
Journal of the American Chemical Society 2011;133(38):15184-90.
2011: Armida Torreggiani; S Barata-Vallejo; Chryssostomos Chatgilialoglu
Combined Raman and IR spectroscopic study on the radical-based modifications of methionine.
Analytical and bioanalytical chemistry 2011;401(4):1231-9.
2011: Branka Mihaljević; Ivana Tartaro; Carla Ferreri; Chryssostomos Chatgilialoglu
Linoleic acid peroxidation vs. isomerization: a biomimetic model of free radical reactivity in the presence of thiols.
Organic & biomolecular chemistry 2011;9(9):3541-8.
2011: Chryssostomos Chatgilialoglu; Clara Caminal; Quinto G Mulazzani
Radical-based alkylation of guanine derivatives in aqueous medium.
Organic & biomolecular chemistry 2011;9(9):3494-8.
2011: Chryssostomos Chatgilialoglu; Carla Ferreri; Michael A Terzidis
Purine 5',8-cyclonucleoside lesions: chemistry and biology.
Chemical Society reviews 2011;40(3):1368-82.
2011: Anna Maria Salzano; Giovanni Renzone; Andrea Scaloni; Armida Torreggiani; Carla Ferreri; Chryssostomos Chatgilialoglu
Human serum albumin modifications associated with reductive radical stress.
Molecular bioSystems 2011;7(3):889-98.
2011: Danila Fazio; Christian Trindler; Korbinian Heil; Chryssostomos Chatgilialoglu; Thomas Carell
Investigation of excess-electron transfer in DNA double-duplex systems allows estimation of absolute excess-electron transfer and CPD cleavage rates.
Chemistry (Weinheim an der Bergstrasse, Germany) 2011;17(1):206-12.
2010: Riccardo Amorati; Luca Valgimigli; Gian Franco Pedulli; Stanislav A Grabovskiy; Natalia N Kabal'nova; Chryssostomos Chatgilialoglu
Base-promoted reaction of 5-hydroxyuracil derivatives with peroxyl radicals.
Organic letters 2010;12(18):4130-3.
2010: Nourreddine Belmadoui; Fabien Boussicault; Maurizio Guerra; Jean-Luc Ravanat; Chryssostomos Chatgilialoglu; Jean CADET
Radiation-induced formation of purine 5',8-cyclonucleosides in isolated and cellular DNA: high stereospecificity and modulating effect of oxygen.
Organic & biomolecular chemistry 2010;8(14):3211-9.
2010: Sebastián Barata-Vallejo; Carla Ferreri; Al Postigo; Chryssostomos Chatgilialoglu
Radiation chemical studies of methionine in aqueous solution: understanding the role of molecular oxygen.
Chemical research in toxicology 2010;23(1):258-63.
2009: Panagiotis Kaloudis; Mila D'Angelantonio; Maurizio Guerra; Marie Spadafora; Crina Cismaş; Thanasis Gimisis; Quinto G Mulazzani; Chryssostomos Chatgilialoglu
Comparison of isoelectronic 8-HO-G and 8-NH2-G derivatives in redox processes.
Journal of the American Chemical Society 2009;131(43):15895-902.
2009: Armida Torreggiani; Jordi Domènech; Ruben Orihuela; Carla Ferreri; Sílvia Atrian; Mercè Capdevila; Chryssostomos Chatgilialoglu
Zinc and cadmium complexes of a plant metallothionein under radical stress: desulfurisation reactions associated with the formation of trans-lipids in model membranes.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(24):6015-24.
2009: Mila D'Angelantonio; Marialuisa Russo; Panagiotis Kaloudis; Quinto G Mulazzani; Peter Wardman; Maurizio Guerra; Chryssostomos Chatgilialoglu
Reaction of hydrated electrons with guanine derivatives: tautomerism of intermediate species.
The journal of physical chemistry. B 2009;113(7):2170-6.
2009: Carla Ferreri; Chryssostomos Chatgilialoglu
Membrane lipidomics and the geometry of unsaturated fatty acids from biomimetic models to biological consequences.
Methods in molecular biology (Clifton, N.J.) 2009;579():391-411.
2009: Chryssostomos Chatgilialoglu; Mila D'Angelantonio; Maurizio Guerra; Panagiotis Kaloudis; Quinto G Mulazzani
A reevaluation of the ambident reactivity of the guanine moiety towards hydroxyl radicals.
Angewandte Chemie (International ed. in English) 2009;48(12):2214-7.
2008: Carla Ferreri; Dimitris Anagnostopoulos; Ioannis N Lykakis; Chryssostomos Chatgilialoglu; Athanassia Siafaka-Kapadai
Synthesis of all-trans anandamide: a substrate for fatty acid amide hydrolase with dual effects on rabbit platelet activation.
Bioorganic & medicinal chemistry 2008;16(18):8359-65.
2008: Fabien Boussicault; Panagiotis Kaloudis; Clara Caminal; Quinto G Mulazzani; Chryssostomos Chatgilialoglu
The fate of C5' radicals of purine nucleosides under oxidative conditions.
Journal of the American Chemical Society 2008;130(26):8377-85.
2008: Carla Ferreri; Chryssostomos Chatgilialoglu; Armida Torreggiani; Anna Maria Salzano; Giovanni Renzone; Andrea Scaloni
The reductive desulfurization of Met and Cys residues in bovine RNase A is associated with trans lipids formation in a mimetic model of biological membranes.
Journal of proteome research 2008;7(5):2007-15.
2008: Panagiotis Kaloudis; Mila D'Angelantonio; Maurizio Guerra; Thanasis Gimisis; Quinto G Mulazzani; Chryssostomos Chatgilialoglu
One-electron reduction of 8-bromo-2-aminoadenosine in the aqueous phase: radiation chemical and DFT studies of the mechanism.
The journal of physical chemistry. B 2008;112(16):5209-17.
2008: Liliana B Jimenez; Susana Encinas; Chryssostomos Chatgilialoglu; Miguel A Miranda
Solar one-way photoisomerisation of 5',8-cyclo-2'-deoxyadenosine.
Organic & biomolecular chemistry 2008;6(6):1083-6.
2008: AA Puca; Peter Andrew; Valeria Novelli; Chiara Viviani Anselmi; Francesco Somalvico; Nicola A Cirillo; Chryssostomos Chatgilialoglu; Carla Ferreri
Fatty acid profile of erythrocyte membranes as possible biomarker of longevity.
Rejuvenation research 2008;11(1):63-72.
2008: Chryssostomos Chatgilialoglu
(Me3Si)3SiH: twenty years after its discovery as a radical-based reducing agent.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(8):2310-20.
2008: AA Puca; Chryssostomos Chatgilialoglu; Carla Ferreri
Lipid metabolism and diet: possible mechanisms of slow aging.
The international journal of biochemistry & cell biology 2008;40(3):324-33.
2007: Al Postigo; Sergey Kopsov; Carla Ferreri; Chryssostomos Chatgilialoglu
Radical reactions in aqueous medium using (Me3Si)3SiH.
Organic letters 2007;9(25):5159-62.
2007: Chryssostomos Chatgilialoglu; Rita Bazzanini; Liliana B Jimenez; Miguel A Miranda
(5'S)- and (5'R)-5',8-cyclo-2'-deoxyguanosine: mechanistic insights on the 2'-deoxyguanosin-5'-yl radical cyclization.
Chemical research in toxicology 2007;20(12):1820-4.
2007: Carla Ferreri; Maria Panagiotaki; Chryssostomos Chatgilialoglu
Trans fatty acids in membranes: the free radical path.
Molecular biotechnology 2007;37(1):19-25.
2007: Oleksiy Itsenko; Daniel Norberg; Torben Rasmussen; Bengt Långström; Chryssostomos Chatgilialoglu
Radical carbonylation with [11C]carbon monoxide promoted by oxygen-centered radicals: experimental and DFT studies of the mechanism.
Journal of the American Chemical Society 2007;129(29):9020-31.
2007: Maurizio Tamba; Katalin Dajka; Carla Ferreri; Klaus-Dieter Asmus; Chryssostomos Chatgilialoglu
One-electron reduction of methanesulfonyl chloride. The fate of MeSO2Cl(.)(-) and MeSO2(.) intermediates in oxygenated solutions and their role in the cis-trans isomerization of mono-unsaturated fatty acids.
Journal of the American Chemical Society 2007;129(28):8716-23.
2007: Antonio Manetto; Dimitris Georganakis; Leondios Leondiadis; Thanasis Gimisis; Peter Mayer; Thomas Carell; Chryssostomos Chatgilialoglu
Independent generation of C5'-nucleosidyl radicals in thymidine and 2'-deoxyguanosine.
The Journal of organic chemistry 2007;72(10):3659-66.
2007: Chryssostomos Chatgilialoglu; Maurizio Guerra; Panagiotis Kaloudis; Chantal Houée-Lévin; Jean-Louis Marignier; Vijay N Swaminathan; Thomas Carell
Ring opening of the cyclobutane in a thymine dimer radical anion.
Chemistry (Weinheim an der Bergstrasse, Germany) 2007;13(32):8979-84.
2007: Ioannis N Lykakis; Carla Ferreri; Chryssostomos Chatgilialoglu
The sulfhydryl radical (HS(.)/S(.-)): a contender for the isomerization of double bonds in membrane lipids.
Angewandte Chemie (International ed. in English) 2007;46(11):1914-6.
2007: Olivier Mozziconacci; Krzysztof Bobrowski; Carla Ferreri; Chryssostomos Chatgilialoglu
Reactions of hydrogen atoms with met-enkephalin and related peptides.
Chemistry (Weinheim an der Bergstrasse, Germany) 2007;13(7):2029-33.
2006: Carla Ferreri; Immacolata Manco; M Rosaria Faraone Mennella; Armida Torreggiani; Maurizio Tamba; Sonia Manara; Chryssostomos Chatgilialoglu
The reaction of hydrogen atoms with methionine residues: A model of reductive radical stress causing tandem protein-lipid damage.
Chembiochem : a European journal of chemical biology 2006;7(11):1738-44.
2006: Chryssostomos Chatgilialoglu; Clara Caminal; Alessio Altieri; Georgios Vougioukalakis; Quinto G Mulazzani; Thanasis Gimisis; Maurizio Guerra
Tautomerism in the guanyl radical.
Journal of the American Chemical Society 2006;128(42):13796-805.
2006: Marialuisa Russo; Liliana B Jimenez; Quinto G Mulazzani; Mila D'Angelantonio; Maurizio Guerra; Miguel A Miranda; Chryssostomos Chatgilialoglu
Chemical radiation studies of 8-bromo-2'-deoxyinosine and 8-bromoinosine in aqueous solutions.
Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(29):7684-93.
2006: Chryssostomos Chatgilialoglu; Carla Ferreri; Ioannis N Lykakis; Peter Wardman
Trans-fatty acids and radical stress: what are the real culprits?
Bioorganic & medicinal chemistry 2006;14(18):6144-8.
2006: Maria Luisa Navacchia; Chryssostomos Chatgilialoglu; Pier Carlo Montevecchi
C5'-adenosinyl radical cyclization. A stereochemical investigation.
The Journal of organic chemistry 2006;71(12):4445-52.
2006: Laura Zambonin; Carla Ferreri; Luciana Cabrini; Cecilia Prata; Chryssostomos Chatgilialoglu; Laura Landi
Occurrence of trans fatty acids in rats fed a trans-free diet: a free radical-mediated formation?
Free radical biology & medicine 2006;40(9):1549-56.
2006: Vojtech Kadlcik; Cécile Sicard-Roselli; Chantal Houée-Levin; Milan Kodicek; Carla Ferreri; Chryssostomos Chatgilialoglu
Reductive modification of a methionine residue in the amyloid-beta peptide.
Angewandte Chemie (International ed. in English) 2006;45(16):2595-8.
2006: Carla Ferreri; Silvia Pierotti; Chryssostomos Chatgilialoglu; Andrea Barbieri; Francesco Barigelletti
Probing the influence of cis-trans isomers on model lipid membrane fluidity using cis-parinaric acid and a stop-flow technique.
Chemical communications (Cambridge, England) 2006;(5):529-31.
2006: Armida Torreggiani; Maurizio Tamba; Immacolata Manco; M Rosaria Faraone Mennella; Carla Ferreri; Chryssostomos Chatgilialoglu
Investigation of radical-based damage of RNase A in aqueous solution and lipid vesicles.
Biopolymers 2006;81(1):39-50.
2006: Carla Ferreri; Silvia Pierotti; Andrea Barbieri; Laura Zambonin; Laura Landi; Silvia Rasi; Pier Luigi Luisi; Francesco Barigelletti; Chryssostomos Chatgilialoglu
Comparison of phosphatidylcholine vesicle properties related to geometrical isomerism.
Photochemistry and photobiology 2006;82(1):274-80.
2005: Antonio Manetto; Sascha Breeger; Chryssostomos Chatgilialoglu; Thomas Carell
Complex sequence dependence by excess-electron transfer through DNA with different strength electron acceptors.
Angewandte Chemie (International ed. in English) 2005;45(2):318-21.
2005: Carla Ferreri; Chryssostomos Chatgilialoglu
Geometrical trans lipid isomers: a new target for lipidomics.
Chembiochem : a European journal of chemical biology 2005;6(10):1722-34.
2005: Chryssostomos Chatgilialoglu; Clara Caminal; Maurizio Guerra; Quinto G Mulazzani
Tautomers of one-electron-oxidized guanosine.
Angewandte Chemie (International ed. in English) 2005;44(37):6030-2.
2005: Carla Ferreri; Federica Angelini; Chryssostomos Chatgilialoglu; Sergio Dellonte; Viviana Moschese; Paolo Rossi; Loredana Chini
Trans fatty acids and atopic eczema/dermatitis syndrome: the relationship with a free radical cis-trans isomerization of membrane lipids.
Lipids 2005;40(7):661-7.
2005: Antonio Faucitano; Armando Buttafava; Mario Mariani; Chryssostomos Chatgilialoglu
The influence of solid-state molecular organization on the reaction paths of thiyl radicals.
Chemphyschem : a European journal of chemical physics and physical chemistry 2005;6(6):1100-7.
2005: Dimitris Anagnostopoulos; Chryssostomos Chatgilialoglu; Carla Ferreri; Abdelouahid Samadi; Athanassia Siafaka-Kapadai
Synthesis of all-trans arachidonic acid and its effect on rabbit platelet aggregation.
Bioorganic & medicinal chemistry letters 2005;15(11):2766-70.
2005: Chryssostomos Chatgilialoglu; Carla Ferreri
Trans lipids: the free radical path.
Accounts of chemical research 2005;38(6):441-8.
2005: Carla Ferreri; Susanne Kratzsch; Ortwin Brede; Bronislaw Marciniak; Chryssostomos Chatgilialoglu
Trans lipid formation induced by thiols in human monocytic leukemia cells.
Free radical biology & medicine 2005;38(9):1180-7.
2005: Chryssostomos Chatgilialoglu; Abdelouahid Samadi; Maurizio Guerra; Hanns Fischer
The kinetics of Z/E isomerization of methyl oleate catalyzed by photogenerated thiyl radicals.
Chemphyschem : a European journal of chemical physics and physical chemistry 2005;6(2):286-91.
2004: Carla Ferreri; Immacolata Manco; M Rosaria Faraone Mennella; Armida Torreggiani; Maurizio Tamba; Chryssostomos Chatgilialoglu
A biomimetic model of tandem radical damage involving sulfur-containing proteins and unsaturated lipids.
Chembiochem : a European journal of chemical biology 2004;5(12):1710-2.
2004: Liliana B Jimenez; Susana Encinas; Miguel A Miranda; Maria Luisa Navacchia; Chryssostomos Chatgilialoglu
The photochemistry of 8-bromo-2'-deoxyadenosine. A direct entry to cyclopurine lesions.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2004;3(11-12):1042-6.
2004: Marcella de Champdore; Lorenzo De Napoli; Daniela Montesarchio; gennaro Piccialli; Clara Caminal; Quinto G Mulazzani; Maria Luisa Navacchia; Chryssostomos Chatgilialoglu
Excess electron transfer in G-quadruplex.
Chemical communications (Cambridge, England) 2004;(15):1756-7.
2004: Chryssostomos Chatgilialoglu; Maria Duca; Carla Ferreri; Maurizio Guerra; Marcella Ioele; Quinto G Mulazzani; Harald Strittmatter; Bernd Giese
Selective generation and reactivity of 5'-adenosinyl and 2'-adenosinyl radicals.
Chemistry (Weinheim an der Bergstrasse, Germany) 2004;10(5):1249-55.
2004: Carla Ferreri; Abdelouahid Samadi; Fabio Sassatelli; Laura Landi; Chryssostomos Chatgilialoglu
Regioselective cis-trans isomerization of arachidonic double bonds by thiyl radicals: the influence of phospholipid supramolecular organization.
Journal of the American Chemical Society 2004;126(4):1063-72.
2004: Chryssostomos Chatgilialoglu; Carla Ferreri; Thanasis Gimisis; Marinella Roberti; Jan Balzarini; Erik De Clercq
Synthesis and biological evaluation of novel 1'-branched and spironucleoside analogues.
Nucleosides, nucleotides & nucleic acids 2004;23(10):1565-81.
2003: Vitaliy I Timokhin; Stéphane Gastaldi; Michèle P Bertrand; Chryssostomos Chatgilialoglu
Rate constants for the beta-elimination of tosyl radical from a variety of substituted carbon-centered radicals.
The Journal of organic chemistry 2003;68(9):3532-7.
2003: Chryssostomos Chatgilialoglu; Maurizio Guerra; Quinto G Mulazzani
Model studies of DNA C5' radicals. Selective generation and reactivity of 2'-deoxyadenosin-5'-yl radical.
Journal of the American Chemical Society 2003;125(13):3839-48.
2002: Chryssostomos Chatgilialoglu; Laura Zambonin; Alessio Altieri; Carla Ferreri; Quinto G Mulazzani; Laura Landi
Geometrical isomerism of monounsaturated fatty acids: thiyl radical catalysis and influence of antioxidant vitamins.
Free radical biology & medicine 2002;33(12):1681-92.
2002: Carla Ferreri; M Rosaria Faraone Mennella; Cesare Formisano; Laura Landi; Chryssostomos Chatgilialoglu
Arachidonate geometrical isomers generated by thiyl radicals: the relationship with trans lipids detected in biological samples.
Free radical biology & medicine 2002;33(11):1516-26.
2002: Chryssostomos Chatgilialoglu; Alessio Altieri; Hanns Fischer
The kinetics of thiyl radical-induced reactions of monounsaturated fatty acid esters.
Journal of the American Chemical Society 2002;124(43):12816-23.
2002: Chryssostomos Chatgilialoglu; Carla Ferreri; Maurizio Guerra; Vitaliy I Timokhin; Georgios Froudakis; Thanasis Gimisis
5-Endo-trig radical cyclizations: disfavored or favored processes?
Journal of the American Chemical Society 2002;124(36):10765-72.
2001: Carla Ferreri; C Costantino; L Perrotta; Laura Landi; Quinto G Mulazzani; Chryssostomos Chatgilialoglu
Cis-trans isomerization of polyunsaturated fatty acid residues in phospholipids catalyzed by thiyl radicals.
Journal of the American Chemical Society 2001;123(19):4459-68.