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Irshad Chaudry

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
165
Bland, Kirby
143
Wang, Ping
136
Ayala, Alfred
108
Schwacha, Martin
91
Choudhry, Mashkoor
69
Ba, Zheng
57
Cioffi, William
42
Rue, Loring
39
Angele, Martin
36
Hsieh, Ya-Ching
24
Yu, Huang-Ping
22
Suzuki, Takao
22
Jarrar, Doraid
21
Knöferl, Markus
21
Shimizu, Tomoharu

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Publications

TOP 3
Hsieh Chi-Hsun; Hsu Jun-Te; Hsieh Ya-Ching; Frink Michael; Raju Raghavan; Hubbard William J; Bland Kirby I; Chaudry Irshad H
Suppression of activation and costimulatory signaling in splenic CD4+ T cells after trauma-hemorrhage reduces T-cell function: a mechanism of post-traumatic immune suppression.
Li Xiaoling; Chaudry Irshad H; Choudhry Mashkoor A
ERK and not p38 pathway is required for IL-12 restoration of T cell IL-2 and IFN-gamma in a rodent model of alcohol intoxication and burn injury.
Walz Christian R; Zedler Siegfried; Schneider Christian P; Albertsmeier Markus; Loehe Florian; Bruns Christiane J; Faist Eugen; Chaudry Irshad H; Angele Martin K
The potential role of T-cells and their interaction with antigen-presenting cells in mediating immunosuppression following trauma-hemorrhage.

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All Publications

2009: Hsieh Chi-Hsun; Hsu Jun-Te; Hsieh Ya-Ching; Frink Michael; Raju Raghavan; Hubbard William J; Bland Kirby I; Chaudry Irshad H
Suppression of activation and costimulatory signaling in splenic CD4+ T cells after trauma-hemorrhage reduces T-cell function: a mechanism of post-traumatic immune suppression.
The American journal of pathology 2009;175(4):1504-14.
2009: Li Xiaoling; Chaudry Irshad H; Choudhry Mashkoor A
ERK and not p38 pathway is required for IL-12 restoration of T cell IL-2 and IFN-gamma in a rodent model of alcohol intoxication and burn injury.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(6):3955-62.
2009: Walz Christian R; Zedler Siegfried; Schneider Christian P; Albertsmeier Markus; Loehe Florian; Bruns Christiane J; Faist Eugen; Chaudry Irshad H; Angele Martin K
The potential role of T-cells and their interaction with antigen-presenting cells in mediating immunosuppression following trauma-hemorrhage.
Innate immunity 2009;15(4):233-41.
2009: Hsu Jun-Te; Kan Wen-Hong; Hsieh Chi-Hsun; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
Mechanism of salutary effects of estrogen on cardiac function following trauma-hemorrhage: Akt-dependent HO-1 up-regulation.
Critical care medicine 2009;37(8):2338-44.
2009: Akhtar Suhail; Li Xiaoling; Chaudry Irshad H; Choudhry Mashkoor A
Neutrophil chemokines and their role in IL-18-mediated increase in neutrophil O2- production and intestinal edema following alcohol intoxication and burn injury.
American journal of physiology. Gastrointestinal and liver physiology 2009;297(2):G340-7.
2009: Yang Shaolong; Hu Shunhua; Chen Jianguo; Choudhry Mashkoor A; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Mechanism of hepatoprotection in proestrus female rats following trauma-hemorrhage: heme oxygenase-1-derived normalization of hepatic inflammatory responses.
Journal of leukocyte biology 2009;85(6):1015-26.
2009: Hsieh Chi-Hsun; Nickel Eike A; Chen Jianguo; Schwacha Martin G; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
Mechanism of the salutary effects of estrogen on kupffer cell phagocytic capacity following trauma-hemorrhage: pivotal role of Akt activation.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(7):4406-14.
2009: Nickel Eike A; Hsieh Chi-Hsun; Chen Jianguo G; Schwacha Martin G; Chaudry Irshad H
Estrogen suppresses cardiac IL-6 after trauma-hemorrhage via a hypoxia-inducible factor 1 alpha-mediated pathway.
Shock (Augusta, Ga.) 2009;31(4):354-8.
2009: Hsieh Ya-Ching; Athar Mohammad; Chaudry Irshad H
When apoptosis meets autophagy: deciding cell fate after trauma and sepsis.
Trends in molecular medicine 2009;15(3):129-38.
2009: Yu Huang-Ping; Chaudry Irshad H
The role of estrogen and receptor agonists in maintaining organ function after trauma-hemorrhage.
Shock (Augusta, Ga.) 2009;31(3):227-37.
2009: Hsu Jun-Te; Kan Wen-Hong; Hsieh Chi-Hsun; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
Role of extracellular signal-regulated protein kinase (ERK) in 17beta-estradiol-mediated attenuation of lung injury after trauma-hemorrhage.
Surgery 2009;145(2):226-34.
2009: Zou Luyun; Yang Shaolong; Champattanachai Voraratt; Hu Shunhua; Chaudry Irshad H; Marchase Richard B; Chatham John C
Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NF-{kappa}B signaling.
American journal of physiology. Heart and circulatory physiology 2009;296(2):H515-23.
2009: Kawasaki Takashi; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Effect of interleukin-15 on depressed splenic dendritic cell functions following trauma-hemorrhage.
American journal of physiology. Cell physiology 2009;296(1):C124-30.
2008: Chen Jianguo; Yang Shaolong; Hu Shunhua; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
Estrogen prevents intestinal inflammation after trauma-hemorrhage via downregulation of angiotensin II and angiotensin II subtype I receptor.
American journal of physiology. Gastrointestinal and liver physiology 2008;295(5):G1131-7.
2008: Ba Zheng F; Chaudry Irshad H
Role of estrogen receptor subtypes in estrogen-induced organ-specific vasorelaxation after trauma-hemorrhage.
American journal of physiology. Heart and circulatory physiology 2008;295(5):H2061-7.
2008: Moeinpour Fariba; Choudhry Mashkoor A; de Figueiredo Luiz F Poli; Bland Kirby I; Chaudry Irshad H
Estradiol's salutary effects on keratinocytes following trauma-hemorrhage are mediated by estrogen receptor (ER)-alpha and ER-beta.
Molecular medicine (Cambridge, Mass.) 2008;14(11-12):689-96.
2008: Ba Zheng F; Hsu Jun-Te; Chen Jianguo; Kan Wen-Hong; Schwacha Martin G; Chaudry Irshad H
Systematic analysis of the salutary effect of estrogen on cardiac performance after trauma-hemorrhage.
Shock (Augusta, Ga.) 2008;30(5):585-9.
2008: Kan Wen-Hong; Hsu Jun-Te; Schwacha Martin G; Choudhry Mashkoor A; Raju Raghavan; Bland Kirby I; Chaudry Irshad H
Selective inhibition of iNOS attenuates trauma-hemorrhage/resuscitation-induced hepatic injury.
Journal of applied physiology (Bethesda, Md. : 1985) 2008;105(4):1076-82.
2008: Hsu Jun-Te; Kan Wen-Hong; Hsieh Ya-Ching; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Mechanism of estrogen-mediated improvement in cardiac function after trauma-hemorrhage: p38-dependent normalization of cardiac Akt phosphorylation and glycogen levels.
Shock (Augusta, Ga.) 2008;30(4):372-8.
2008: Hsieh Chi-Hsun; Frink Michael; Hsieh Ya-Ching; Kan Wen-Hong; Hsu Jun-Te; Schwacha Martin G; Choudhry Mashkoor A; Chaudry Irshad H
The role of MIP-1 alpha in the development of systemic inflammatory response and organ injury following trauma hemorrhage.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(4):2806-12.
2008: Kan Wen-Hong; Hsu Jun-Te; Schwacha Martin G; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
Estrogen ameliorates trauma-hemorrhage-induced lung injury via endothelial nitric oxide synthase-dependent activation of protein kinase G.
Annals of surgery 2008;248(2):294-302.
2008: Kan Wen-Hong; Hsieh Chi-Hsun; Schwacha Martin G; Choudhry Mashkoor A; Raju Raghavan; Bland Kirby I; Chaudry Irshad H
Flutamide protects against trauma-hemorrhage-induced liver injury via attenuation of the inflammatory response, oxidative stress, and apopotosis.
Journal of applied physiology (Bethesda, Md. : 1985) 2008;105(2):595-602.
2008: Choudhry Mashkoor A; Chaudry Irshad H
Alcohol, burn injury, and the intestine.
Journal of emergencies, trauma and shock 2008;1(2):81-7.
2008: Raju Raghavan; Chaudry Irshad H
Sex steroids/receptor antagonist: their use as adjuncts after trauma-hemorrhage for improving immune/cardiovascular responses and for decreasing mortality from subsequent sepsis.
Anesthesia and analgesia 2008;107(1):159-66.
2008: Shimizu Tomoharu; Suzuki Takao; Yu Huang-Ping; Yokoyama Yukihiro; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
The role of estrogen receptor subtypes on hepatic neutrophil accumulation following trauma-hemorrhage: direct modulation of CINC-1 production by Kupffer cells.
Cytokine 2008;43(1):88-92.
2008: Hsu Jun-Te; Kan Wen-Hong; Hsieh Chi-Hsun; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Mechanism of estrogen-mediated intestinal protection following trauma-hemorrhage: p38 MAPK-dependent upregulation of HO-1.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;294(6):R1825-31.
2008: Kan Wen-Hong; Hsu Jun-Te; Ba Zheng-Feng; Schwacha Martin G; Chen Jianguo; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
p38 MAPK-dependent eNOS upregulation is critical for 17beta-estradiol-mediated cardioprotection following trauma-hemorrhage.
American journal of physiology. Heart and circulatory physiology 2008;294(6):H2627-36.
2008: Li Xiaoling; Schwacha Martin G; Chaudry Irshad H; Choudhry Mashkoor A
Heme oxygenase-1 protects against neutrophil-mediated intestinal damage by down-regulation of neutrophil p47phox and p67phox activity and O2- production in a two-hit model of alcohol intoxication and burn injury.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(10):6933-40.
2008: Li Xiaoling; Schwacha Martin G; Chaudry Irshad H; Choudhry Mashkoor A
Inhibition of protein tyrosine phosphatases prevents mesenteric lymph node T-cell suppression following alcohol intoxication and burn injury.
Journal of burn care & research : official publication of the American Burn Association 2008;29(3):519-30.
2008: Suzuki Takao; Yu Huang-Ping; Hsieh Ya-Ching; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
Mitogen activated protein kinase (MAPK) mediates non-genomic pathway of estrogen on T cell cytokine production following trauma-hemorrhage.
Cytokine 2008;42(1):32-8.
2008: Raju Raghavan; Bland Kirby I; Chaudry Irshad H
Estrogen: a novel therapeutic adjunct for the treatment of trauma-hemorrhage-induced immunological alterations.
Molecular medicine (Cambridge, Mass.) 2008;14(3-4):213-21.
2008: Kawasaki Takashi; Choudhry Mashkoor A; Schwacha Martin G; Fujimi Satoshi; Lederer James A; Bland Kirby I; Chaudry Irshad H
Trauma-hemorrhage inhibits splenic dendritic cell proinflammatory cytokine production via a mitogen-activated protein kinase process.
American journal of physiology. Cell physiology 2008;294(3):C754-64.
2008: Li Xiaoling; Schwacha Martin G; Chaudry Irshad H; Choudhry Mashkoor A
Acute alcohol intoxication potentiates neutrophil-mediated intestinal tissue damage after burn injury.
Shock (Augusta, Ga.) 2008;29(3):377-83.
2008: Choudhry Mashkoor A; Chaudry Irshad H
17beta-Estradiol: a novel hormone for improving immune and cardiovascular responses following trauma-hemorrhage.
Journal of leukocyte biology 2008;83(3):518-22.
2008: Suzuki Takao; Yu Huang-Ping; Hsieh Ya-Ching; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
Estrogen-mediated activation of non-genomic pathway improves macrophages cytokine production following trauma-hemorrhage.
Journal of cellular physiology 2008;214(3):662-72.
2008: Cuzzocrea Salvatore; Genovese Tiziana; Mazzon Emanuela; Esposito Emanuela; Di Paola Rosanna; Muià Carmelo; Crisafulli Concetta; Peli Angelo; Bramanti Placido; Chaudry Irshad H
Effect of 17beta-estradiol on signal transduction pathways and secondary damage in experimental spinal cord trauma.
Shock (Augusta, Ga.) 2008;29(3):362-71.
2008: Lederer James A; Brownstein Bernard H; Lopez M Cecilia; Macmillan Sandra; Delisle Adam J; Macconmara Malcolm P; Choudhry Mashkoor A; Xiao Wenzhong; Lekousi Steven; Cobb J Perren; Baker Henry V; Mannick John A; Chaudry Irshad H;
Comparison of longitudinal leukocyte gene expression after burn injury or trauma-hemorrhage in mice.
Physiological genomics 2008;32(3):299-310.
2008: Kawasaki Takashi; Choudhry Mashkoor A; Suzuki Takao; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
17beta-Estradiol's salutary effects on splenic dendritic cell functions following trauma-hemorrhage are mediated via estrogen receptor-alpha.
Molecular immunology 2008;45(2):376-85.
2008: Angele Martin K; Schneider Christian P; Chaudry Irshad H
Bench-to-bedside review: latest results in hemorrhagic shock.
Critical care (London, England) 2008;12(4):218.
2007: Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
Trauma and immune response--effect of gender differences.
Injury 2007;38(12):1382-91.
2007: Frink Michael; Hsieh Ya-Ching; Hsieh Chi-Hsun; Pape Hans-Christoph; Choudhry Mashkoor A; Schwacha Martin G; Chaudry Irshad H
Keratinocyte-derived chemokine plays a critical role in the induction of systemic inflammation and tissue damage after trauma-hemorrhage.
Shock (Augusta, Ga.) 2007;28(5):576-81.
2007: Frink Michael; Hsieh Ya-Ching; Hu Shunhua; Hsieh Chi-Hsun; Pape Hans-Christoph; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Mechanism of salutary effects of finasteride on post-traumatic immune/inflammatory response: upregulation of estradiol synthesis.
Annals of surgery 2007;246(5):836-43.
2007: Hsu Jun-Te; Kan Wen-Hong; Hsieh Chi-Hsun; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Mechanism of estrogen-mediated attenuation of hepatic injury following trauma-hemorrhage: Akt-dependent HO-1 up-regulation.
Journal of leukocyte biology 2007;82(4):1019-26.
2007: Hsieh Ya-Ching; Frink Michael; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
Metabolic modulators following trauma sepsis: sex hormones.
Critical care medicine 2007;35(9 Suppl):S621-9.
2007: Yu Huang-Ping; Hsieh Ya-Ching; Suzuki Takao; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Mechanism of the nongenomic effects of estrogen on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of the PI-3K/Akt pathway.
Journal of leukocyte biology 2007;82(3):774-80.
2007: Suzuki Takao; Shimizu Tomoharu; Yu Huang-Ping; Hsieh Ya-Ching; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
Estrogen receptor-alpha predominantly mediates the salutary effects of 17beta-estradiol on splenic macrophages following trauma-hemorrhage.
American journal of physiology. Cell physiology 2007;293(3):C978-84.
2007: Daniel Tanjanika; Thobe Bjoern M; Chaudry Irshad H; Choudhry Mashkoor A; Hubbard William J; Schwacha Martin G
Regulation of the postburn wound inflammatory response by gammadelta T-cells.
Shock (Augusta, Ga.) 2007;28(3):278-83.
2007: Kashiwabara Moto; Miyashita Masao; Nomura Tsutomu; Makino Hiroshi; Matsutani Takeshi; Kim Chol; Takeda Shinhiro; Yamashita Kiyohiko; Chaudry Irshad H; Tajiri Takashi
Surgical trauma-induced adrenal insufficiency is associated with postoperative inflammatory responses.
Journal of Nippon Medical School = Nihon Ika Daigaku zasshi 2007;74(4):274-83.
2007: Moeinpour Fariba; Choudhry Mashkoor A; Kawasaki Takashi; Timares Laura; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
17 Beta-estradiol normalizes Toll receptor 4, mitogen activated protein kinases and inflammatory response in epidermal keratinocytes following trauma-hemorrhage.
Molecular immunology 2007;44(13):3317-23.
2007: Yu Huang-Ping; Hsieh Ya-Ching; Suzuki Takao; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
The PI3K/Akt pathway mediates the nongenomic cardioprotective effects of estrogen following trauma-hemorrhage.
Annals of surgery 2007;245(6):971-7.
2007: Shimizu Tomoharu; Yu Huang-Ping; Suzuki Takao; Szalay László; Hsieh Ya-Ching; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
The role of estrogen receptor subtypes in ameliorating hepatic injury following trauma-hemorrhage.
Journal of hepatology 2007;46(6):1047-54.
2007: Hsu Jun-Te; Hsieh Ya-Ching; Kan Wen Hong; Chen Jian Guo; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Role of p38 mitogen-activated protein kinase pathway in estrogen-mediated cardioprotection following trauma-hemorrhage.
American journal of physiology. Heart and circulatory physiology 2007;292(6):H2982-7.
2007: Suzuki Takao; Shimizu Tomoharu; Yu Huang-Ping; Hsieh Ya-Ching; Choudhry Mashkoor A; Chaudry Irshad H
Salutary effects of 17beta-estradiol on T-cell signaling and cytokine production after trauma-hemorrhage are mediated primarily via estrogen receptor-alpha.
American journal of physiology. Cell physiology 2007;292(6):C2103-11.
2007: Hsieh Ya-Ching; Frink Michael; Hsieh Chi-Hsun; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Downregulation of migration inhibitory factor is critical for estrogen-mediated attenuation of lung tissue damage following trauma-hemorrhage.
American journal of physiology. Lung cellular and molecular physiology 2007;292(5):L1227-32.
2007: Li Xiaoling; Kovacs Elizabeth J; Schwacha Martin G; Chaudry Irshad H; Choudhry Mashkoor A
Acute alcohol intoxication increases interleukin-18-mediated neutrophil infiltration and lung inflammation following burn injury in rats.
American journal of physiology. Lung cellular and molecular physiology 2007;292(5):L1193-201.
2007: Hsieh Ya-Ching; Frink Michael; Kawasaki Takashi; Thobe Bjoern M; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Downregulation of TLR4-dependent ATP production is critical for estrogen-mediated immunoprotection in Kupffer cells following trauma-hemorrhage.
Journal of cellular physiology 2007;211(2):364-70.
2007: Zou Luyun; Yang Shaolong; Hu Shunhua; Chaudry Irshad H; Marchase Richard B; Chatham John C
The protective effects of PUGNAc on cardiac function after trauma-hemorrhage are mediated via increased protein O-GlcNAc levels.
Shock (Augusta, Ga.) 2007;27(4):402-8.
2007: Hsieh Ya-Ching; Yu Huang-Ping; Frink Michael; Suzuki Takao; Choudhry Mashkoor A; Schwacha Martin G; Chaudry Irshad H
G protein-coupled receptor 30-dependent protein kinase A pathway is critical in nongenomic effects of estrogen in attenuating liver injury after trauma-hemorrhage.
The American journal of pathology 2007;170(4):1210-8.
2007: Frink Michael; Hsieh Ya-Ching; Thobe Bjoern M; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
TLR4 regulates Kupffer cell chemokine production, systemic inflammation and lung neutrophil infiltration following trauma-hemorrhage.
Molecular immunology 2007;44(10):2625-30.
2007: Yang Shaolong; Hu Shunhua; Choudhry Mashkoor A; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Anti-rat soluble IL-6 receptor antibody down-regulates cardiac IL-6 and improves cardiac function following trauma-hemorrhage.
Journal of molecular and cellular cardiology 2007;42(3):620-30.
2007: Hsieh Ya-Ching; Frink Michael; Thobe Bjoern M; Hsu Jun-Te; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
17Beta-estradiol downregulates Kupffer cell TLR4-dependent p38 MAPK pathway and normalizes inflammatory cytokine production following trauma-hemorrhage.
Molecular immunology 2007;44(9):2165-72.
2007: Thobe Bjoern M; Frink Michael; Hildebrand Frank; Schwacha Martin G; Hubbard William J; Choudhry Mashkoor A; Chaudry Irshad H
The role of MAPK in Kupffer cell toll-like receptor (TLR) 2-, TLR4-, and TLR9-mediated signaling following trauma-hemorrhage.
Journal of cellular physiology 2007;210(3):667-75.
2007: Kiang Juliann G; Peckham Russell M; Duke Leah E; Shimizu Tomoharu; Chaudry Irshad H; Tsokos George C
Androstenediol inhibits the trauma-hemorrhage-induced increase in caspase-3 by downregulating the inducible nitric oxide synthase pathway.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;102(3):933-41.
2007: Frink Michael; Lu Ailing; Thobe Bjoern M; Hsieh Ya-Ching; Choudhry Mashkoor A; Schwacha Martin G; Kunkel Steven L; Chaudry Irshad H
Monocyte chemoattractant protein-1 influences trauma-hemorrhage-induced distal organ damage via regulation of keratinocyte-derived chemokine production.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;292(3):R1110-6.
2007: Shimizu Tomoharu; Yu Huang-Ping; Hsieh Ya-Ching; Choudhry Mashkoor A; Suzuki Takao; Bland Kirby I; Chaudry Irshad H
Flutamide attenuates pro-inflammatory cytokine production and hepatic injury following trauma-hemorrhage via estrogen receptor-related pathway.
Annals of surgery 2007;245(2):297-304.
2007: Frink Michael; Pape Hans-Christoph; van Griensven Martijn; Krettek Christian; Chaudry Irshad H; Hildebrand Frank
Influence of sex and age on mods and cytokines after multiple injuries.
Shock (Augusta, Ga.) 2007;27(2):151-6.
2007: Frink Michael; Thobe Bjoern M; Hsieh Ya-Ching; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
17beta-Estradiol inhibits keratinocyte-derived chemokine production following trauma-hemorrhage.
American journal of physiology. Lung cellular and molecular physiology 2007;292(2):L585-91.
2007: Kawai Toru; Yokoyama Yukihiro; Kawai Satoru; Yokoyama Shinya; Oda Koji; Nagasaka Tetsuro; Nagino Masato; Chaudry Irshad H; Nimura Yuji
Does estrogen contribute to the hepatic regeneration following portal branch ligation in rats?
American journal of physiology. Gastrointestinal and liver physiology 2007;292(2):G582-9.
2007: Lu Ailing; Frink Michael; Choudhry Mashkoor A; Schwacha Martin G; Hubbard William J; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Mitochondria play an important role in 17beta-estradiol attenuation of H(2)O(2)-induced rat endothelial cell apoptosis.
American journal of physiology. Endocrinology and metabolism 2007;292(2):E585-93.
2007: Ba Zheng F; Lu Ailing; Shimizu Tomoharu; Szalay László; Schwacha Martin G; Rue Loring W; Bland Kirby I; Chaudry Irshad H
17beta-Estradiol modulates vasoconstriction induced by endothelin-1 following trauma-hemorrhage.
American journal of physiology. Heart and circulatory physiology 2007;292(1):H245-50.
2007: Matsutani Takeshi; Kang Shih-Ching; Miyashita Masao; Sasajima Koji; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
Young and middle-age associated differences in cytokeratin expression after bone fracture, tissue trauma, and hemorrhage.
American journal of surgery 2007;193(1):61-8.
2007: Schneider Christian P; Schwacha Martin G; Chaudry Irshad H
Impact of sex and age on bone marrow immune responses in a murine model of trauma-hemorrhage.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;102(1):113-21.
2007: Suzuki Takao; Shimizu Tomoharu; Yu Huang-Ping; Hsieh Ya-Ching; Choudhry Mashkoor A; Schwacha Martin G; Chaudry Irshad H
Tissue compartment-specific role of estrogen receptor subtypes in immune cell cytokine production following trauma-hemorrhage.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;102(1):163-8.
2007: Matsutani Takeshi; Kang Shih-Ching; Miyashita Masao; Sasajima Koji; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
Liver cytokine production and ICAM-1 expression following bone fracture, tissue trauma, and hemorrhage in middle-aged mice.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(1):G268-74.
2006: Choudhry Mashkoor A; Li Xiaoling; Chaudry Irshad H
A role for corticosterone in impaired intestinal immunity and barrier function in a rodent model of acute alcohol intoxication and burn injury.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2006;1(4):428-34.
2006: Yang Shaolong; Choudhry Mashkoor A; Hsieh Ya-Ching; Hu Shunhua; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Estrus cycle: influence on cardiac function following trauma-hemorrhage.
American journal of physiology. Heart and circulatory physiology 2006;291(6):H2807-15.
2006: Hildebrand Frank; Thobe Bjoern M; Hubbard William J; Choudhry Mashkoor A; Pape Hans-Christoph; Chaudry Irshad H
Effects of 17beta-estradiol and flutamide on splenic macrophages and splenocytes after trauma-hemorrhage.
Cytokine 2006;36(3-4):107-14.
2006: Kawasaki Takashi; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Lidocaine depresses splenocyte immune functions following trauma-hemorrhage in mice.
American journal of physiology. Cell physiology 2006;291(5):C1049-55.
2006: Angele Martin K; Frantz Markus C; Chaudry Irshad H
Gender and sex hormones influence the response to trauma and sepsis: potential therapeutic approaches.
Clinics (São Paulo, Brazil) 2006;61(5):479-88.
2006: Kawasaki Takashi; Fujimi Satoshi; Lederer James A; Hubbard William J; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Trauma-hemorrhage induces depressed splenic dendritic cell functions in mice.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(7):4514-20.
2006: Hildebrand Frank; Hubbard William J; Choudhry Mashkoor A; Thobe Bjoern M; Pape Hans-Christoph; Chaudry Irshad H
Effects of 17beta-estradiol and flutamide on inflammatory response and distant organ damage following trauma-hemorrhage in metestrus females.
Journal of leukocyte biology 2006;80(4):759-65.
2006: Hildebrand Frank; Hubbard William J; Choudhry Mashkoor A; Frink Michael; Pape Hans-Christoph; Kunkel Steven L; Chaudry Irshad H
Kupffer cells and their mediators: the culprits in producing distant organ damage after trauma-hemorrhage.
The American journal of pathology 2006;169(3):784-94.
2006: Hsieh Ya-Ching; Yu Huang-Ping; Suzuki Takao; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Upregulation of mitochondrial respiratory complex IV by estrogen receptor-beta is critical for inhibiting mitochondrial apoptotic signaling and restoring cardiac functions following trauma-hemorrhage.
Journal of molecular and cellular cardiology 2006;41(3):511-21.
2006: Thobe Björn M; Frink Michael; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Src family kinases regulate p38 MAPK-mediated IL-6 production in Kupffer cells following hypoxia.
American journal of physiology. Cell physiology 2006;291(3):C476-82.
2006: Yu Huang-Ping; Yang Shaolong; Hsieh Ya-Ching; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
Maintenance of lung myeloperoxidase activity in proestrus females after trauma-hemorrhage: upregulation of heme oxygenase-1.
American journal of physiology. Lung cellular and molecular physiology 2006;291(3):L400-6.
2006: Suzuki Takao; Shimizu Tomoharu; Yu Huang-Ping; Hsieh Ya-Ching; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
17 beta-estradiol administration following trauma-hemorrhage prevents the increase in Kupffer cell cytokine production and MAPK activation predominately via estrogen receptor-alpha.
Surgery 2006;140(2):141-8.
2006: Li Xiaoling; Rana Shadab N; Schwacha Martin G; Chaudry Irshad H; Choudhry Mashkoor A
A novel role for IL-18 in corticosterone-mediated intestinal damage in a two-hit rodent model of alcohol intoxication and injury.
Journal of leukocyte biology 2006;80(2):367-75.
2006: Daniel Tanjanika; Alexander Michelle; Hubbard William J; Chaudry Irshad H; Choudhry Mashkoor A; Schwacha Martin G
Nitric oxide contributes to the development of a post-injury Th2 T-cell phenotype and immune dysfunction.
Journal of cellular physiology 2006;208(2):418-27.
2006: Mayr S; Walz C R; Angele P; Hernandez-Richter T; Chaudry I H; Loehe F; Jauch K W; Angele M K
Castration prevents suppression of MHC class II (Ia) expression on macrophages after trauma-hemorrhage.
Journal of applied physiology (Bethesda, Md. : 1985) 2006;101(2):448-53.
2006: Szalay László; Shimizu Tomoharu; Suzuki Takao; Hsieh Ya-Ching; Choudhry Mashkoor A; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Androstenediol administration after trauma-hemorrhage attenuates inflammatory response, reduces organ damage, and improves survival following sepsis.
American journal of physiology. Gastrointestinal and liver physiology 2006;291(2):G260-6.
2006: Kerby Jeffrey D; McGwin Gerald; George Richard L; Cross James A; Chaudry Irshad H; Rue Loring W
Sex differences in mortality after burn injury: results of analysis of the National Burn Repository of the American Burn Association.
Journal of burn care & research : official publication of the American Burn Association 2006;27(4):452-6.
2006: Shimizu Tomoharu; Szalay László; Hsieh Ya-Ching; Suzuki Takao; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
A role of PPAR-gamma in androstenediol-mediated salutary effects on cardiac function following trauma-hemorrhage.
Annals of surgery 2006;244(1):131-8.
2006: Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
Gender and susceptibility to sepsis following trauma.
Endocrine, metabolic & immune disorders drug targets 2006;6(2):127-35.
2006: Hsieh Ya-Ching; Choudhry Mashkoor A; Yu Huang-Ping; Shimizu Tomoharu; Yang Shaolong; Suzuki Takao; Chen Jianguo; Bland Kirby I; Chaudry Irshad H
Inhibition of cardiac PGC-1alpha expression abolishes ERbeta agonist-mediated cardioprotection following trauma-hemorrhage.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(8):1109-17.
2006: Hildebrand Frank; Hubbard William J; Choudhry Mashkoor A; Thobe Bjoern M; Pape Hans-Christoph; Chaudry Irshad H
Are the protective effects of 17beta-estradiol on splenic macrophages and splenocytes after trauma-hemorrhage mediated via estrogen-receptor (ER)-alpha or ER-beta?
Journal of leukocyte biology 2006;79(6):1173-80.
2006: Wang Xiangdong; Adler Kenneth B; Chaudry Irshad H; Ward Peter A
Better understanding of organ dysfunction requires proteomic involvement.
Journal of proteome research 2006;5(5):1060-2.
2006: Yu Huang-Ping; Shimizu Tomoharu; Hsieh Ya-Ching; Suzuki Takao; Choudhry Mashkoor A; Schwacha Martin G; Chaudry Irshad H
Tissue-specific expression of estrogen receptors and their role in the regulation of neutrophil infiltration in various organs following trauma-hemorrhage.
Journal of leukocyte biology 2006;79(5):963-70.
2006: Yu Huang-Ping; Hsieh Ya-Ching; Suzuki Takao; Shimizu Tomoharu; Choudhry Mashkoor A; Schwacha Martin G; Chaudry Irshad H
Salutary effects of estrogen receptor-beta agonist on lung injury after trauma-hemorrhage.
American journal of physiology. Lung cellular and molecular physiology 2006;290(5):L1004-9.
2006: Zheng Rui; Pan George; Thobe Bjoern M; Choudhry Mashkoor A; Matsutani Takeshi; Samy T S Anantha; Kang Shih-Ching; Bland Kirby I; Chaudry Irshad H
MyD88 and Src are differentially regulated in Kupffer cells of males and proestrus females following hypoxia.
Molecular medicine (Cambridge, Mass.) 2006;12(4-6):65-73.
2006: Suzuki Takao; Shimizu Tomoharu; Szalay Laszlo; Choudhry Mashkoor A; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Androstenediol ameliorates alterations in immune cells cytokine production capacity in a two-hit model of trauma-hemorrhage and sepsis.
Cytokine 2006;34(1-2):76-84.
2006: Yang Shaolong; Hu Shunhua; Hsieh Ya-Ching; Choudhry Mashkoor A; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Mechanism of IL-6-mediated cardiac dysfunction following trauma-hemorrhage.
Journal of molecular and cellular cardiology 2006;40(4):570-9.
2006: Li Xiaoling; Schwacha Martin G; Chaudry Irshad H; Choudhry Mashkoor A
A role of PP1/PP2A in mesenteric lymph node T cell suppression in a two-hit rodent model of alcohol intoxication and injury.
Journal of leukocyte biology 2006;79(3):453-62.
2006: Schneider Christian P; Schwacha Martin G; Chaudry Irshad H
Influence of gender and age on T-cell responses in a murine model of trauma-hemorrhage: differences between circulating and tissue-fixed cells.
Journal of applied physiology (Bethesda, Md. : 1985) 2006;100(3):826-33.
2006: Szalay László; Shimizu Tomoharu; Suzuki Takao; Yu Huang-Ping; Choudhry Mashkoor A; Schwacha Martin G; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Estradiol improves cardiac and hepatic function after trauma-hemorrhage: role of enhanced heat shock protein expression.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(3):R812-8.
2006: Brownstein Bernard H; Logvinenko Tanya; Lederer James A; Cobb J Perren; Hubbard William J; Chaudry Irshad H; Remick Daniel G; Baker Henry V; Xiao Wenzhong; Mannick John A
Commonality and differences in leukocyte gene expression patterns among three models of inflammation and injury.
Physiological genomics 2006;24(3):298-309.
2006: Yu Huang-Ping; Choudhry Mashkoor A; Shimizu Tomoharu; Hsieh Ya-Ching; Schwacha Martin G; Yang Shaolong; Chaudry Irshad H
Mechanism of the salutary effects of flutamide on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of estrogen receptor-{beta}-dependent HO-1.
Journal of leukocyte biology 2006;79(2):277-84.
2006: Alexander Michelle; Daniel TanJanika; Chaudry Irshad H; Choudhry Mashkoor A; Schwacha Martin G
T cells of the gammadelta T-cell receptor lineage play an important role in the postburn wound healing process.
Journal of burn care & research : official publication of the American Burn Association 2006;27(1):18-25.
2006: Yu Huang-Ping; Shimizu Tomoharu; Choudhry Mashkoor A; Hsieh Ya-Ching; Suzuki Takao; Bland Kirby I; Chaudry Irshad H
Mechanism of cardioprotection following trauma-hemorrhagic shock by a selective estrogen receptor-beta agonist: up-regulation of cardiac heat shock factor-1 and heat shock proteins.
Journal of molecular and cellular cardiology 2006;40(1):185-94.
2006: Hsieh Ya-Ching; Yang Shaolong; Choudhry Mashkoor A; Yu Huang-Ping; Bland Kirby I; Schwacha Martin G; Chaudry Irshad H
Flutamide restores cardiac function after trauma-hemorrhage via an estrogen-dependent pathway through upregulation of PGC-1.
American journal of physiology. Heart and circulatory physiology 2006;290(1):H416-23.
2006: Choudhry Mashkoor A; Chaudry Irshad H
Alcohol intoxication and post-burn complications.
Frontiers in bioscience : a journal and virtual library 2006;11():998-1005.
2005: Choudhry Mashkoor A; Schwacha Martin G; Hubbard William J; Kerby Jeffrey D; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Gender differences in acute response to trauma-hemorrhage.
Shock (Augusta, Ga.) 2005;24 Suppl 1():101-6.
2005: Hubbard William J; Choudhry Mashkoor; Schwacha Martin G; Kerby Jeffrey D; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Cecal ligation and puncture.
Shock (Augusta, Ga.) 2005;24 Suppl 1():52-7.
2005: Hsieh Ya-Ching; Yang Shaolong; Choudhry Mashkoor A; Yu Huang-Ping; Rue Loring W; Bland Kirby I; Chaudry Irshad H
PGC-1 upregulation via estrogen receptors: a common mechanism of salutary effects of estrogen and flutamide on heart function after trauma-hemorrhage.
American journal of physiology. Heart and circulatory physiology 2005;289(6):H2665-72.
2005: Alexander Michelle; Daniel TanJanika; Chaudry Irshad H; Schwacha Martin G
Opiate analgesics contribute to the development of post-injury immunosuppression.
The Journal of surgical research 2005;129(1):161-8.
2005: Matsuda Akihisa; Furukawa Kiyonori; Suzuki Hideyuki; Matsutani Takeshi; Tajiri Takashi; Chaudry Irshad H
Dehydroepiandrosterone modulates toll-like receptor expression on splenic macrophages of mice after severe polymicrobial sepsis.
Shock (Augusta, Ga.) 2005;24(4):364-9.
2005: George Richard L; McGwin Gerald; Schwacha Martin G; Metzger Jesse; Cross James M; Chaudry Irshad H; Rue Loring W
The association between sex and mortality among burn patients as modified by age.
The Journal of burn care & rehabilitation 2005;26(5):416-21.
2005: Yokoyama Yukihiro; Nimura Yuji; Nagino Masato; Bland Kirby I; Chaudry Irshad H
Current understanding of gender dimorphism in hepatic pathophysiology.
The Journal of surgical research 2005;128(1):147-56.
2005: Shimizu Tomoharu; Szalay Laszlo; Hsieh Ya-Ching; Choudhry Mashkoor A; Bland Kirby I; Chaudry Irshad H
Salutary effects of androstenediol on hepatic function after trauma-hemorrhage are mediated via peroxisome proliferators-activated receptor gamma.
Surgery 2005;138(2):204-11.
2005: Yokoyama Yukihiro; Nimura Yuji; Nagino Masato; Bland Kirby I; Chaudry Irshad H
Role of thromboxane in producing hepatic injury during hepatic stress.
Archives of surgery (Chicago, Ill. : 1960) 2005;140(8):801-7.
2005: Frantz Markus C; Prix Niclas J; Wichmann Matthias W; van den Engel Natasja K; Hernandez-Richter Thomas; Faist Eugen; Chaudry Irshad H; Jauch Karl-Walter; Angele Martin K
Dehydroepiandrosterone restores depressed peripheral blood mononuclear cell function following major abdominal surgery via the estrogen receptors.
Critical care medicine 2005;33(8):1779-86.
2005: Angele Martin K; Chaudry Irshad H
Surgical trauma and immunosuppression: pathophysiology and potential immunomodulatory approaches.
Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie 2005;390(4):333-41.
2005: Wittmann F; Prix N; Mayr S; Angele P; Wichmann M W; van den Engel N K; Hernandez-Richter T; Chaudry I H; Jauch K W; Angele Martin K
L-arginine improves wound healing after trauma-hemorrhage by increasing collagen synthesis.
The Journal of trauma 2005;59(1):162-8.
2005: Yu Huang-Ping; Yang Shaolong; Choudhry Mashkoor A; Hsieh Ya-Ching; Bland Kirby I; Chaudry Irshad H
Mechanism responsible for the salutary effects of flutamide on cardiac performance after trauma-hemorrhagic shock: Upregulation of cardiomyocyte estrogen receptors.
Surgery 2005;138(1):85-92.
2005: Szalay László; Shimizu Tomoharu; Schwacha Martin G; Choudhry Mashkoor A; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Mechanism of salutary effects of estradiol on organ function after trauma-hemorrhage: upregulation of heme oxygenase.
American journal of physiology. Heart and circulatory physiology 2005;289(1):H92-8.
2005: Li Xiaoling; Rana Shadab N; Kovacs Elizabeth J; Gamelli Richard L; Chaudry Irshad H; Choudhry Mashkoor A
Corticosterone suppresses mesenteric lymph node T cells by inhibiting p38/ERK pathway and promotes bacterial translocation after alcohol and burn injury.
American journal of physiology. Regulatory, integrative and comparative physiology 2005;289(1):R37-44.
2005: Matsutani Takeshi; Anantha Samy T S; Kang Shih-Ching; Bland Kirby I; Chaudry Irshad H
Mouse genetic background influences severity of immune responses following trauma-hemorrhage.
Cytokine 2005;30(4):168-76.
2005: Rana Shadab N; Li Xiaoling; Chaudry Irshad H; Bland Kirby I; Choudhry Mashkoor A
Inhibition of IL-18 reduces myeloperoxidase activity and prevents edema in intestine following alcohol and burn injury.
Journal of leukocyte biology 2005;77(5):719-28.
2005: Matsutani Takeshi; Samy T S Anantha; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Transgenic prolactin-/- mice: effect of trauma-hemorrhage on splenocyte functions.
American journal of physiology. Cell physiology 2005;288(5):C1109-16.
2005: Ba Zheng F; Shimizu Tomoharu; Szalay Laszlo; Bland Kirby I; Chaudry Irshad H
Gender differences in small intestinal perfusion following trauma hemorrhage: the role of endothelin-1.
American journal of physiology. Gastrointestinal and liver physiology 2005;288(5):G860-5.
2005: Schwacha Martin G; Holland Lawanda T; Chaudry Irshad H; Messina Joseph L
Genetic variability in the immune-inflammatory response after major burn injury.
Shock (Augusta, Ga.) 2005;23(2):123-8.
2005: Choudhry Mashkoor A; Ba Zheng F; Rana Shadab N; Bland Kirby I; Chaudry Irshad H
Alcohol ingestion before burn injury decreases splanchnic blood flow and oxygen delivery.
American journal of physiology. Heart and circulatory physiology 2005;288(2):H716-21.
2005: Shimizu Tomoharu; Szalay Laszlo; Choudhry Mashkoor A; Schwacha Martin G; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Mechanism of salutary effects of androstenediol on hepatic function after trauma-hemorrhage: role of endothelial and inducible nitric oxide synthase.
American journal of physiology. Gastrointestinal and liver physiology 2005;288(2):G244-50.
2004: Toth Balazs; Yokoyama Yukihiro; Schwacha Martin G; George Richard L; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Insights into the role of interleukin-6 in the induction of hepatic injury after trauma-hemorrhagic shock.
Journal of applied physiology (Bethesda, Md. : 1985) 2004;97(6):2184-9.
2004: Hubbard William J; Bland Kirby I; Chaudry Irshad H
The role of the mitochondrion in trauma and shock.
Shock (Augusta, Ga.) 2004;22(5):395-402.
2004: Yang Shaolong; Zheng Rui; Hu Shunhua; Ma Yuchen; Choudhry Mashkoor A; Messina Joseph L; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Mechanism of cardiac depression after trauma-hemorrhage: increased cardiomyocyte IL-6 and effect of sex steroids on IL-6 regulation and cardiac function.
American journal of physiology. Heart and circulatory physiology 2004;287(5):H2183-91.
2004: Shih-Ching Kang; Choudhry Mashkoor A; Matsutani Takeshi; Schwacha Martin G; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Splenectomy differentially influences immune responses in various tissue compartments of the body.
Cytokine 2004;28(3):101-8.
2004: Ma Yuchen; Toth Balazs; Keeton Adam B; Holland Lawanda T; Chaudry Irshad H; Messina Joseph L
Mechanisms of hemorrhage-induced hepatic insulin resistance: role of tumor necrosis factor-alpha.
Endocrinology 2004;145(11):5168-76.
2004: Alexander Michelle; Daniel Tanjanika; Chaudry Irshad H; Schwacha Martin G
MAP kinases differentially regulate the expression of macrophage hyperactivity after thermal injury.
Journal of cellular physiology 2004;201(1):35-44.
2004: Yokoyama Yukihiro; Toth Balazs; Kitchens William C; Schwacha Martin G; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Estradiol's effect on portal response to endothelin-1 after trauma-hemorrhage.
The Journal of surgical research 2004;121(1):25-30.
2004: Toth Balazs; Alexander Michelle; Daniel TanJanika; Chaudry Irshad H; Hubbard William J; Schwacha Martin G
The role of gammadelta T cells in the regulation of neutrophil-mediated tissue damage after thermal injury.
Journal of leukocyte biology 2004;76(3):545-52.
2004: Jarrar Doraid; Song Grace Y; Kuebler Joachim F; Rue Loring W; Bland Kirby I; Chaudry Irshad H
The effect of inhibition of a major cell signaling pathway following trauma hemorrhage on hepatic injury and interleukin 6 levels.
Archives of surgery (Chicago, Ill. : 1960) 2004;139(8):896-901.
2004: Eckhoff Devin E; Eckstein Christopher; Smyth Cheryl A; Vilatoba Mario; Bilbao Guadalupe; Rahemtulla Firoz G; Young Carlton J; Anthony Thompson J; Chaudry Irshad H; Contreras Juan L
Enhanced isolated pancreatic islet recovery and functionality in rats by 17beta-estradiol treatment of brain death donors.
Surgery 2004;136(2):336-45.
2004: Shimizu Tomoharu; Choudhry Mashkoor A; Szalay Laszlo; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Salutary effects of androstenediol on cardiac function and splanchnic perfusion after trauma-hemorrhage.
American journal of physiology. Regulatory, integrative and comparative physiology 2004;287(2):R386-90.
2004: Kang Shih-Ching; Matsutani Takeshi; Choudhry Mashkoor A; Schwacha Martin G; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Are the immune responses different in middle-aged and young mice following bone fracture, tissue trauma and hemorrhage?
Cytokine 2004;26(5):223-30.
2004: Kuebler Joachim F; Toth Balazs; Yokoyama Yukihiro; Bland Kirby I; Rue Loring W; Chaudry Irshad H
Alpha1-acid-glycoprotein protects against trauma-hemorrhagic shock.
The Journal of surgical research 2004;119(1):21-8.
2004: Yokoyama Yukihiro; Kitchens William C; Toth Balazs; Schwacha Martin G; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Role of IL-10 in regulating proinflammatory cytokine release by Kupffer cells following trauma-hemorrhage.
American journal of physiology. Gastrointestinal and liver physiology 2004;286(6):G942-6.
2004: Schneider Christian P; Schwacha Martin G; Chaudry Irshad H
The role of interleukin-10 in the regulation of the systemic inflammatory response following trauma-hemorrhage.
Biochimica et biophysica acta 2004;1689(1):22-32.
2004: Ba Zheng F; Yokoyama Yukihiro; Toth Balazs; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Gender differences in small intestinal endothelial function: inhibitory role of androgens.
American journal of physiology. Gastrointestinal and liver physiology 2004;286(3):G452-7.
2004: Nitsch Stefan M; Wittmann Florian; Angele Peter; Wichmann Matthias W; Hatz Rudolf; Hernandez-Richter Thomas; Chaudry Irshad H; Jauch Karl W; Angele Martin K
Physiological levels of 5 alpha-dihydrotestosterone depress wound immune function and impair wound healing following trauma-hemorrhage.
Archives of surgery (Chicago, Ill. : 1960) 2004;139(2):157-63.
2004: Dienstknecht Thomas; Schwacha Martin G; Kang Shih Ching; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Sex steroid-mediated regulation of macrophage/monocyte function in a two-hit model of trauma-hemorrhage and sepsis.
Cytokine 2004;25(3):110-8.
2004: Jarrar Doraid; Wang Ping; Chaudry Irshad H
Metabolic disturbances in shock, and the role of ATP-MgCl2 and sex steroids.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2004;13(1):2-9.
2003: Toth Balazs; Yokoyama Yukihiro; Kuebler Joachim F; Schwacha Martin G; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Sex differences in hepatic heme oxygenase expression and activity following trauma and hemorrhagic shock.
Archives of surgery (Chicago, Ill. : 1960) 2003;138(12):1375-82.
2003: Contreras Juan L; Eckstein Christopher; Smyth Cheryl A; Sellers Marty T; Vilatoba Mario; Bilbao Guadalupe; Rahemtulla Firoz G; Young Carlton J; Thompson J Anthony; Chaudry Irshad H; Eckhoff Devin E
Brain death significantly reduces isolated pancreatic islet yields and functionality in vitro and in vivo after transplantation in rats.
Diabetes 2003;52(12):2935-42.
2003: Schwacha Martin G; Chaudry Irshad H; Alexander Michelle
Regulation of macrophage IL-10 production postinjury via beta2 integrin signaling and the P38 MAP kinase pathway.
Shock (Augusta, Ga.) 2003;20(6):529-35.
2003: Yokoyama Yukihiro; Toth Balazs; Kitchens William C; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Role of thromboxane in producing portal hypertension following trauma-hemorrhage.
American journal of physiology. Gastrointestinal and liver physiology 2003;285(6):G1293-9.
2003: Yokoyama Yukihiro; Kitchens Williams C; Toth Balazs; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Upregulation of hepatic prolactin receptor gene expression by 17beta-estradiol following trauma-hemorrhage.
Journal of applied physiology (Bethesda, Md. : 1985) 2003;95(6):2530-6.
2003: Chung Chun-Shiang; Song Grace Y; Lomas Joanne; Simms H Hank; Chaudry Irshad H; Ayala Alfred
Inhibition of Fas/Fas ligand signaling improves septic survival: differential effects on macrophage apoptotic and functional capacity.
Journal of leukocyte biology 2003;74(3):344-51.
2003: Kuebler Joachim F; Toth Balazs; Rue Loring W; Wang Ping; Bland Kirby I; Chaudry Irshad H
Differential fluid regulation during and after soft tissue trauma and hemorrhagic shock in males and proestrus females.
Shock (Augusta, Ga.) 2003;20(2):144-8.
2003: Knoferl Markus W; Angele Martin K; Catania Robert A; Diodato Michael D; Bland Kirby I; Chaudry Irshad H
Immunomodulatory effects of dehydroepiandrosterone in proestrus female mice after trauma-hemorrhage.
Journal of applied physiology (Bethesda, Md. : 1985) 2003;95(2):529-35.
2003: Kuebler Joachim F; Yokoyama Yukihiro; Jarrar Doraid; Toth Balazs; Rue Loring W; Bland Kirby I; Wang Ping; Chaudry Irshad H
Administration of progesterone after trauma and hemorrhagic shock prevents hepatocellular injury.
Archives of surgery (Chicago, Ill. : 1960) 2003;138(7):727-34.
2003: Angele Martin K; Nitsch Stefan; Knoferl Markus W; Ayala Alfred; Angele Peter; Schildberg Friedrich W; Jauch Karl W; Chaudry Irshad H
Sex-specific p38 MAP kinase activation following trauma-hemorrhage: involvement of testosterone and estradiol.
American journal of physiology. Endocrinology and metabolism 2003;285(1):E189-96.
2003: Schneider Christian P; Schwacha Martin G; Samy T S Anantha; Bland Kirby I; Chaudry Irshad H
Androgen-mediated modulation of macrophage function after trauma-hemorrhage: central role of 5alpha-dihydrotestosterone.
Journal of applied physiology (Bethesda, Md. : 1985) 2003;95(1):104-12.
2003: Samy T S Anantha; Zheng Rui; Matsutani Takeshi; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Mechanism for normal splenic T lymphocyte functions in proestrus females after trauma: enhanced local synthesis of 17beta-estradiol.
American journal of physiology. Cell physiology 2003;285(1):C139-49.
2003: Kuebler Joachim F; Toth Balazs; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Differential alterations in intestinal permeability after trauma-hemorrhage.
The Journal of surgical research 2003;112(2):198-204.
2003: Kuebler Joachim F; Jarrar Doraid; Bland Kirby I; Rue Loring; Wang Ping; Chaudry Irshad H
Progesterone administration after trauma and hemorrhagic shock improves cardiovascular responses.
Critical care medicine 2003;31(6):1786-93.
2003: Ba Zheng F; Kuebler Joachim F; Rue Loring W; Bland Kirby I; Wang Ping; Chaudry Irshad H
Gender dimorphic tissue perfusion response after acute hemorrhage and resuscitation: role of vascular endothelial cell function.
American journal of physiology. Heart and circulatory physiology 2003;284(6):H2162-9.
2003: Chaudry Irshad H; Samy T S Anantha; Schwacha Martin G; Wang Ping; Rue Loring W; Bland Kirby I
Endocrine targets in experimental shock.
The Journal of trauma 2003;54(5 Suppl):S118-25.
2003: Yokoyama Yukihiro; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Effect of estradiol administration on splanchnic perfusion after trauma-hemorrhage and sepsis.
Current opinion in critical care 2003;9(2):137-42.
2003: Knöferl Markus W; Angele Martin K; Schwacha Martin G; Anantha Samy T S; Bland Kirby I; Chaudry Irshad H
Immunoprotection in proestrus females following trauma-hemorrhage: the pivotal role of estrogen receptors.
Cellular immunology 2003;222(1):27-34.
2003: George Richard L; McGwin Gerald; Metzger Jesse; Chaudry Irshad H; Rue Loring W
The association between gender and mortality among trauma patients as modified by age.
The Journal of trauma 2003;54(3):464-71.
2003: Fowler Dale E; Yang Shaolong; Zhou Mian; Chaudry Irshad H; Simms H Hank; Wang Ping
Adrenomedullin and adrenomedullin binding protein-1: their role in the septic response.
The Journal of surgical research 2003;109(2):175-81.
2003: Yokoyama Yukihiro; Kuebler Joachim F; Matsutani Takeshi; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Mechanism of the salutary effects of 17beta-estradiol following trauma-hemorrhage: direct downregulation of Kupffer cell proinflammatory cytokine production.
Cytokine 2003;21(2):91-7.
2003: George Richard L; McGwin Gerald; Windham Sam T; Melton Sherry M; Metzger Jesse; Chaudry Irshad H; Rue Loring W
Age-related gender differential in outcome after blunt or penetrating trauma.
Shock (Augusta, Ga.) 2003;19(1):28-32.
2003: Ma Yuchen; Wang Ping; Kuebler Joachim F; Chaudry Irshad H; Messina Joseph L
Hemorrhage induces the rapid development of hepatic insulin resistance.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(1):G107-15.
2002: Alexander Michelle; Chaudry Irshad H; Schwacha Martin G
Relationships between burn size, immunosuppression, and macrophage hyperactivity in a murine model of thermal injury.
Cellular immunology 2002;220(1):63-9.
2002: Yang Shaolong; Zhou Mian; Chaudry Irshad H; Wang Ping
Novel approach to prevent the transition from the hyperdynamic phase to the hypodynamic phase of sepsis: role of adrenomedullin and adrenomedullin binding protein-1.
Annals of surgery 2002;236(5):625-33.
2002: McGwin Gerald; George Richard L; Cross James M; Reiff Donald A; Chaudry Irshad H; Rue Loring W
Gender differences in mortality following burn injury.
Shock (Augusta, Ga.) 2002;18(4):311-5.
2002: Ba Zheng F; Wang Ping; Kuebler Joachim F; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Flutamide induces relaxation in large and small blood vessels.
Archives of surgery (Chicago, Ill. : 1960) 2002;137(10):1180-6.
2002: Jarrar Doraid; Kuebler Joachim F; Rue Loring W; Matalon Sadis; Wang Ping; Bland Kirby I; Chaudry Irshad H
Alveolar macrophage activation after trauma-hemorrhage and sepsis is dependent on NF-kappaB and MAPK/ERK mechanisms.
American journal of physiology. Lung cellular and molecular physiology 2002;283(4):L799-805.
2002: Zhou Mian; Ba Zheng F; Chaudry Irshad H; Wang Ping
Adrenomedullin binding protein-1 modulates vascular responsiveness to adrenomedullin in late sepsis.
American journal of physiology. Regulatory, integrative and comparative physiology 2002;283(3):R553-60.
2002: Schwacha Martin G; Chaudry Irshad H
The cellular basis of post-burn immunosuppression: macrophages and mediators.
International journal of molecular medicine 2002;10(3):239-43.
2002: Carrico C James; Holcomb John B; Chaudry Irshad H;
Scientific priorities and strategic planning for resuscitation research and life saving therapy following traumatic injury: report of the PULSE Trauma Work Group.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2002;9(6):621-6.
2002: Matsuki Y; Li L; Hsu H-C; Yang P A; Zheng R; Edwards C K; Chaudry I H; Zhang H-G; Mountz J D
Soluble Fas gene therapy protects against Fas-mediated apoptosis of hepatocytes but not the lethal effects of Fas-induced TNF-alpha production by Kupffer cells.
Cell death and differentiation 2002;9(6):626-35.
2002: Zheng Rui; Samy T S Anantha; Schneider Christian P; Rue Loring W; Bland Kirby I; Chaudry Irshad H
Decreased 5alpha-dihydrotestosterone catabolism suppresses T lymphocyte functions in males after trauma-hemorrhage.
American journal of physiology. Cell physiology 2002;282(6):C1332-8.
2002: Nickel Eike A; Schwacha Martin G; Schneider Christian P; Bland Kirby I; Chaudry Irshad H
Trauma-haemorrhage-induced alterations in thymic prolactin receptor expression: implications in immune dysfunction.
Cytokine 2002;18(3):127-32.
2002: Knöferl Markus W; Schwacha Martin G; Jarrar Doraid; Angele Martin K; Fragoza Keith; Bland Kirby I; Chaudry Irshad H
Estrogen pretreatment protects males against hypoxia-induced immune depression.
American journal of physiology. Cell physiology 2002;282(5):C1087-92.
2002: Ornan David A; Chaudry Irshad H; Wang Ping
Saturation of adrenomedullin receptors plays an important role in reducing pulmonary clearance of adrenomedullin during the late stage of sepsis.
Biochimica et biophysica acta 2002;1586(3):299-306.
2002: Knöferl Markus W; Angele Martin K; Schwacha Martin G; Bland Kirby I; Chaudry Irshad H
Preservation of splenic immune functions by female sex hormones after trauma-hemorrhage.
Critical care medicine 2002;30(4):888-93.
2002: Schwacha Martin G; Schneider Christian P; Chaudry Irshad H
Differential expression and tissue compartmentalization of the inflammatory response following thermal injury.
Cytokine 2002;17(5):266-74.
2002: Yang Shaolong; Lim Yow-Pin; Zhou Mian; Salvemini Philomena; Schwinn Horst; Josic Djuro; Koo Douglas J; Chaudry Irshad H; Wang Ping
Administration of human inter-alpha-inhibitors maintains hemodynamic stability and improves survival during sepsis.
Critical care medicine 2002;30(3):617-22.
2002: Carrico C James; Holcomb John B; Chaudry Irshad H;
Scientific priorities and strategic planning for resuscitation research and life saving therapy following traumatic injury: report of the PULSE Trauma Work Group. Post Resuscitative and Initial Utility of Life Saving Efforts.
Shock (Augusta, Ga.) 2002;17(3):165-8.
2002: Schwacha Martin G; Chung Chun-Shiang; Ayala Alfred; Bland Kirby I; Chaudry Irshad H
Cyclooxygenase 2-mediated suppression of macrophage interleukin-12 production after thermal injury.
American journal of physiology. Cell physiology 2002;282(2):C263-70.
2002: Angele Martin K; Nitsch Stefan M; Hatz Rudolf A; Angele Peter; Hernandez-Richter Thomas; Wichmann Mathias W; Chaudry Irshad H; Schildberg Fredrich W
L-arginine: a unique amino acid for improving depressed wound immune function following hemorrhage.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 2002;34(1-2):53-60.
2002: Yang Shaolong; Chung Chun-Shiang; Ayala Alfred; Chaudry Irshad H; Wang Ping
Differential alterations in cardiovascular responses during the progression of polymicrobial sepsis in the mouse.
Shock (Augusta, Ga.) 2002;17(1):55-60.
2002: Kuebler Joachim F; Jarrar Doraid; Toth Balazs; Bland Kirby I; Rue Loring; Wang Ping; Chaudry Irshad H
Estradiol administration improves splanchnic perfusion following trauma-hemorrhage and sepsis.
Archives of surgery (Chicago, Ill. : 1960) 2002;137(1):74-9.
2002: Knöferl Markus W; Angele Martin K; Diodato Michael D; Schwacha Martin G; Ayala Alfred; Cioffi William G; Bland Kirby I; Chaudry Irshad H
Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate from subsequent sepsis.
Annals of surgery 2002;235(1):105-12.
2002: Yokoyama Yukihiro; Schwacha Martin G; Samy T S Anantha; Bland Kirby I; Chaudry Irshad H
Gender dimorphism in immune responses following trauma and hemorrhage.
Immunologic research 2002;26(1-3):63-76.
2001: Knöferl M W; Diodato M D; Schwacha M G; Cioffi W G; Bland K I; Chaudry I H
Cyclooxygenase-2-mediated regulation of Kupffer cell interleukin-6 production following trauma-hemorrhage and subsequent sepsis.
Shock (Augusta, Ga.) 2001;16(6):479-83.
2001: Angele M K; Knöferl M W; Ayala A; Bland K I; Chaudry I H
Testosterone and estrogen differently effect Th1 and Th2 cytokine release following trauma-haemorrhage.
Cytokine 2001;16(1):22-30.
2001: Ba Z F; Wang P; Koo D J; Ornan D A; Bland K I; Chaudry I H
Attenuation of vascular endothelial dysfunction by testosterone receptor blockade after trauma and hemorrhagic shock.
Archives of surgery (Chicago, Ill. : 1960) 2001;136(10):1158-63.
2001: Yang S; Zhou M; Chaudry I H; Wang P
Norepinephrine-induced hepatocellular dysfunction in early sepsis is mediated by activation of alpha2-adrenoceptors.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(4):G1014-21.
2001: Schwacha M G; Schneider C P; Bland K I; Chaudry I H
Resistance of macrophages to the suppressive effect of interleukin-10 following thermal injury.
American journal of physiology. Cell physiology 2001;281(4):C1180-7.
2001: Knöferl M W; Jarrar D; Angele M K; Ayala A; Schwacha M G; Bland K I; Chaudry I H
17 beta-Estradiol normalizes immune responses in ovariectomized females after trauma-hemorrhage.
American journal of physiology. Cell physiology 2001;281(4):C1131-8.
2001: Yang S; Zhou M; Chaudry I H; Wang P
The role of lipopolysaccharide in stimulating adrenomedullin production during polymicrobial sepsis.
Biochimica et biophysica acta 2001;1537(2):167-74.
2001: Samy T S; Knöferl M W; Zheng R; Schwacha M G; Bland K I; Chaudry I H
Divergent immune responses in male and female mice after trauma-hemorrhage: dimorphic alterations in T lymphocyte steroidogenic enzyme activities.
Endocrinology 2001;142(8):3519-29.
2001: Zhou M; Chaudry I H; Wang P
The small intestine is an important source of adrenomedullin release during polymicrobial sepsis.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;281(2):R654-60.
2001: Zhou M; Yang S; Koo D J; Ornan D A; Chaudry I H; Wang P
The role of Kupffer cell alpha(2)-adrenoceptors in norepinephrine-induced TNF-alpha production.
Biochimica et biophysica acta 2001;1537(1):49-57.
2001: Yang S; Koo D J; Chaudry I H; Wang P
Glycine attenuates hepatocellular depression during early sepsis and reduces sepsis-induced mortality.
Critical care medicine 2001;29(6):1201-6.
2001: Diodato M D; Knöferl M W; Schwacha M G; Bland K I; Chaudry I H
Gender differences in the inflammatory response and survival following haemorrhage and subsequent sepsis.
Cytokine 2001;14(3):162-9.
2001: Kuebler J F; Jarrar D; Wang P; Bland K I; Chaudry I H
Dehydroepiandrosterone restores hepatocellular function and prevents liver damage in estrogen-deficient females following trauma and hemorrhage.
The Journal of surgical research 2001;97(2):196-201.
2001: Wang P; Ba Z F; Koo D J; Cioffi W G; Bland K I; Chaudry I H
Continuous resuscitation after hemorrhage and acute fluid replacement improves cardiovascular responses.
Surgery 2001;129(5):559-66.
2001: Chung C S; Wang W; Chaudry I H; Ayala A
Increased apoptosis in lamina propria B cells during polymicrobial sepsis is FasL but not endotoxin mediated.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(5):G812-8.
2001: Ayala A; Chung C S; Song G Y; Chaudry I H
IL-10 mediation of activation-induced TH1 cell apoptosis and lymphoid dysfunction in polymicrobial sepsis.
Cytokine 2001;14(1):37-48.
2001: Koo D J; Jackman D; Chaudry I H; Wang P
Adrenal insufficiency during the late stage of polymicrobial sepsis.
Critical care medicine 2001;29(3):618-22.
2001: Jarrar D; Kuebler J F; Wang P; Bland K I; Chaudry I H
DHEA: a novel adjunct for the treatment of male trauma patients.
Trends in molecular medicine 2001;7(2):81-5.
2001: Zhou M; Arthur A J; Ba Z F; Chaudry I H; Wang P
The small intestine plays an important role in upregulating CGRP during sepsis.
American journal of physiology. Regulatory, integrative and comparative physiology 2001;280(2):R382-8.
2001: Koo D J; Zhou M; Chaudry I H; Wang P
The role of adrenomedullin in producing differential hemodynamic responses during sepsis.
The Journal of surgical research 2001;95(2):207-18.
2001: Song G Y; Chung C S; Jarrar D; Chaudry I H; Ayala A
Evolution of an immune suppressive macrophage phenotype as a product of P38 MAPK activation in polymicrobial sepsis.
Shock (Augusta, Ga.) 2001;15(1):42-8.
2000: Schwacha M G; Knöferl M W; Chaudry I H
Does burn wound excision after thermal injury attenuate subsequent macrophage hyperactivity and immunosuppression?
Shock (Augusta, Ga.) 2000;14(6):623-8.
2000: Wang P; Tait S M; Chaudry I H
Sustained elevation of norepinephrine depresses hepatocellular function.
Biochimica et biophysica acta 2000;1535(1):36-44.
2000: Yang S; Koo D J; Zhou M; Chaudry I H; Wang P
Gut-derived norepinephrine plays a critical role in producing hepatocellular dysfunction during early sepsis.
American journal of physiology. Gastrointestinal and liver physiology 2000;279(6):G1274-81.
2000: Jarrar D; Wang P; Cioffi W G; Bland K I; Chaudry I H
Critical role of oxygen radicals in the initiation of hepatic depression after trauma hemorrhage.
The Journal of trauma 2000;49(5):879-85.
2000: Mizushima Y; Wang P; Jarrar D; Cioffi W G; Bland K I; Chaudry I H
Estradiol administration after trauma-hemorrhage improves cardiovascular and hepatocellular functions in male animals.
Annals of surgery 2000;232(5):673-9.
2000: Ba Z F; Wang P; Koo D J; Zhou M; Cioffi W G; Bland K I; Chaudry I H
Testosterone receptor blockade after trauma and hemorrhage attenuates depressed adrenal function.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;279(5):R1841-8.
2000: Jarrar D; Wang P; Knöferl M W; Ba Z F; Cioffi W G; Bland K I; Chaudry I H
Does early infusion of red blood cells after trauma and hemorrhage improve organ functions?
Critical care medicine 2000;28(10):3498-504.
2000: Samy T S; Schwacha M G; Cioffi W G; Bland K I; Chaudry I H
Androgen and estrogen receptors in splenic T lymphocytes: effects of flutamide and trauma-hemorrhage.
Shock (Augusta, Ga.) 2000;14(4):465-70.
2000: Schneider C P; Nickel E A; Samy T S; Schwacha M G; Cioffi W G; Bland K I; Chaudry I H
The aromatase inhibitor, 4-hydroxyandrostenedione, restores immune responses following trauma-hemorrhage in males and decreases mortality from subsequent sepsis.
Shock (Augusta, Ga.) 2000;14(3):347-53.
2000: Angele M K; Fitzal F; Smail N; Knöferl M W; Schwacha M G; Ayala A; Wang P; Chaudry I H
L-arginine attenuates trauma-hemorrhage-induced liver injury.
Critical care medicine 2000;28(9):3242-8.
2000: Jarrar D; Wang P; Cioffi W G; Bland K I; Chaudry I H
The female reproductive cycle is an important variable in the response to trauma-hemorrhage.
American journal of physiology. Heart and circulatory physiology 2000;279(3):H1015-21.
2000: Ayala A; Song G Y; Chung C S; Redmond K M; Chaudry I H
Immune depression in polymicrobial sepsis: the role of necrotic (injured) tissue and endotoxin.
Critical care medicine 2000;28(8):2949-55.
2000: Ba Z F; Wang P; Koo D J; Cioffi W G; Bland K I; Chaudry I H
Alterations in tissue oxygen consumption and extraction after trauma and hemorrhagic shock.
Critical care medicine 2000;28(8):2837-42.
2000: Angele M K; Schwacha M G; Ayala A; Chaudry I H
Effect of gender and sex hormones on immune responses following shock.
Shock (Augusta, Ga.) 2000;14(2):81-90.
2000: Jarrar D; Wang P; Knöferl M W; Kuebler J F; Cioffi W G; Bland K I; Chaudry I H
Insight into the mechanism by which estradiol improves organ functions after trauma-hemorrhage.
Surgery 2000;128(2):246-52.
2000: Song G Y; Chung C S; Chaudry I H; Ayala A
IL-4-induced activation of the Stat6 pathway contributes to the suppression of cell-mediated immunity and death in sepsis.
Surgery 2000;128(2):133-8.
2000: Knöferl M W; Angele M K; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Insight into the mechanism by which metoclopramide improves immune functions after trauma-hemorrhage.
American journal of physiology. Cell physiology 2000;279(1):C72-80.
2000: Chung C S; Song G Y; Moldawer L L; Chaudry I H; Ayala A
Neither Fas ligand nor endotoxin is responsible for inducible peritoneal phagocyte apoptosis during sepsis/peritonitis.
The Journal of surgical research 2000;91(2):147-53.
2000: Song G Y; Chung C S; Chaudry I H; Ayala A
Immune suppression in polymicrobial sepsis: differential regulation of Th1 and Th2 responses by p38 MAPK.
The Journal of surgical research 2000;91(2):141-6.
2000: Ornan D A; Chaudry I H; Wang P
The dissociation between upregulated endothelins and hemodynamic responses during polymicrobial sepsis.
Biochimica et biophysica acta 2000;1501(2-3):211-8.
2000: Koo D J; Yoo P; Cioffi W G; Bland K I; Chaudry I H; Wang P
Mechanism of the beneficial effects of pentoxifylline during sepsis: maintenance of adrenomedullin responsiveness and downregulation of proinflammatory cytokines.
The Journal of surgical research 2000;91(1):70-6.
2000: Wang P; Zhou M; Cioffi W G; Bland K I; Ba Z F; Chaudry I H
Is prostacyclin responsible for producing the hyperdynamic response during early sepsis?
Critical care medicine 2000;28(5):1534-9.
2000: Chung C S; Song G Y; Wang W; Chaudry I H; Ayala A
Septic mucosal intraepithelial lymphoid immune suppression: role for nitric oxide not interleukin-10 or transforming growth factor-beta.
The Journal of trauma 2000;48(5):807-12; discussion 812-3.
2000: Schwacha M G; Ayala A; Chaudry I H
Insights into the role of gammadelta T lymphocytes in the immunopathogenic response to thermal injury.
Journal of leukocyte biology 2000;67(5):644-50.
2000: Koo D J; Chaudry I H; Wang P
Mechanism of hepatocellular dysfunction during sepsis: the role of gut-derived norepinephrine (review).
International journal of molecular medicine 2000;5(5):457-65.
2000: Knöferl M W; Diodato M D; Angele M K; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Do female sex steroids adversely or beneficially affect the depressed immune responses in males after trauma-hemorrhage?
Archives of surgery (Chicago, Ill. : 1960) 2000;135(4):425-33.
2000: Jarrar D; Wang P; Cioffi W G; Bland K I; Chaudry I H
Mechanisms of the salutary effects of dehydroepiandrosterone after trauma-hemorrhage: direct or indirect effects on cardiac and hepatocellular functions?
Archives of surgery (Chicago, Ill. : 1960) 2000;135(4):416-22; discussion 422-3.
2000: Yang S; Koo D J; Chaudry I H; Wang P
The important role of the gut in initiating the hyperdynamic response during early sepsis.
The Journal of surgical research 2000;89(1):31-7.
2000: Jarrar D; Wang P; Song G Y; Cioffi W G; Bland K I; Chaudry I H
Inhibition of tyrosine kinase signaling after trauma-hemorrhage: a novel approach for improving organ function and decreasing susceptibility to subsequent sepsis.
Annals of surgery 2000;231(3):399-407.
2000: Kahlke V; Angele M K; Schwacha M G; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Reversal of sexual dimorphism in splenic T lymphocyte responses after trauma-hemorrhage with aging.
American journal of physiology. Cell physiology 2000;278(3):C509-16.
2000: Koo D J; Zhou M; Chaudry I H; Wang P
Plasma alpha-glutathione S-transferase: a sensitive indicator of hepatocellular damage during polymicrobial sepsis.
Archives of surgery (Chicago, Ill. : 1960) 2000;135(2):198-203.
2000: Mizushima Y; Wang P; Cioffi W G; Bland K I; Chaudry I H
Restoration of body temperature to normothermia during resuscitation following trauma-hemorrhage improves the depressed cardiovascular and hepatocellular functions.
Archives of surgery (Chicago, Ill. : 1960) 2000;135(2):175-81.
2000: Mizushima Y; Wang P; Jarrar D; Cioffi W G; Bland K I; Chaudry I H
Preinduction of heat shock proteins protects cardiac and hepatic functions following trauma and hemorrhage.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;278(2):R352-9.
2000: Wichmann M W; Zellweger R; Ayala A; Chaudry I H
Effect of naloxone on immune responses after hemorrhagic shock.
Critical care medicine 2000;28(1):184-9.
2000: Mizushima Y; Wang P; Cioffi W G; Bland K I; Chaudry I H
Should normothermia be restored and maintained during resuscitation after trauma and hemorrhage?
The Journal of trauma 2000;48(1):58-65.
2000: Jarrar D; Wang P; Song G Y; Knöferl M W; Cioffi W G; Bland K I; Chaudry I H
Metoclopramide: a novel adjunct for improving cardiac and hepatocellular functions after trauma-hemorrhage.
American journal of physiology. Endocrinology and metabolism 2000;278(1):E90-5.
2000: Kahlke V; Angele M K; Ayala A; Schwacha M G; Cioffi W G; Bland K I; Chaudry I H
Immune dysfunction following trauma-haemorrhage: influence of gender and age.
Cytokine 2000;12(1):69-77.
2000: Shieh P; Zhou M; Ornan D A; Chaudry I H; Wang P
Upregulation of inducible nitric oxide synthase and nitric oxide occurs later than the onset of the hyperdynamic response during sepsis.
Shock (Augusta, Ga.) 2000;13(4):325-9.
1999: Jarrar D; Chaudry I H; Wang P
Organ dysfunction following hemorrhage and sepsis: mechanisms and therapeutic approaches (Review).
International journal of molecular medicine 1999;4(6):575-83.
1999: Yang S; Cioffi W G; Bland K I; Chaudry I H; Wang P
Differential alterations in systemic and regional oxygen delivery and consumption during the early and late stages of sepsis.
The Journal of trauma 1999;47(4):706-12.
1999: Angele M K; Xu Y X; Ayala A; Schwacha M G; Catania R K; Cioffi W G; Bland K I; Chaudry I H
Gender dimorphism in trauma-hemorrhage-induced thymocyte apoptosis.
Shock (Augusta, Ga.) 1999;12(4):316-22.
1999: Schwacha M G; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Role of protein kinase C in cyclic AMP-mediated suppression of T-lymphocyte activation following burn injury.
Biochimica et biophysica acta 1999;1455(1):45-53.
1999: Chaudry I H
Sepsis: lessons learned in the last century and future directions.
Archives of surgery (Chicago, Ill. : 1960) 1999;134(9):922-9.
1999: Yang S; Zhou M; Koo D J; Chaudry I H; Wang P
Pentoxifylline prevents the transition from the hyperdynamic to hypodynamic response during sepsis.
The American journal of physiology 1999;277(3 Pt 2):H1036-44.
1999: Song G Y; Chung C S; Chaudry I H; Ayala A
What is the role of interleukin 10 in polymicrobial sepsis: anti-inflammatory agent or immunosuppressant?
Surgery 1999;126(2):378-83.
1999: Angele M K; Knöferl M W; Ayala A; Albina J E; Cioffi W G; Bland K I; Chaudry I H
Trauma-hemorrhage delays wound healing potentially by increasing pro-inflammatory cytokines at the wound site.
Surgery 1999;126(2):279-85.
1999: Koo D J; Zhou M; Jackman D; Cioffi W G; Bland K I; Chaudry I H; Wang P
Is gut the major source of proinflammatory cytokine release during polymicrobial sepsis?
Biochimica et biophysica acta 1999;1454(3):289-95.
1999: Angele M K; Knöferl M W; Schwacha M G; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Sex steroids regulate pro- and anti-inflammatory cytokine release by macrophages after trauma-hemorrhage.
The American journal of physiology 1999;277(1 Pt 1):C35-42.
1999: Wang P; Yoo P; Zhou M; Cioffi W G; Ba Z F; Chaudry I H
Reduction in vascular responsiveness to adrenomedullin during sepsis.
The Journal of surgical research 1999;85(1):59-65.
1999: Catania R A; Angele M K; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Dehydroepiandrosterone restores immune function following trauma-haemorrhage by a direct effect on T lymphocytes.
Cytokine 1999;11(6):443-50.
1999: Ayala A; Chung C S; Xu Y X; Evans T A; Redmond K M; Chaudry I H
Increased inducible apoptosis in CD4+ T lymphocytes during polymicrobial sepsis is mediated by Fas ligand and not endotoxin.
Immunology 1999;97(1):45-55.
1999: Wang P; Ba Z F; Cioffi W G; Bland K I; Chaudry I H
Salutary effects of ATP-MgCl2 on the depressed endothelium-dependent relaxation during hyperdynamic sepsis.
Critical care medicine 1999;27(5):959-64.
1999: Koo D J; Chaudry I H; Wang P
Kupffer cells are responsible for producing inflammatory cytokines and hepatocellular dysfunction during early sepsis.
The Journal of surgical research 1999;83(2):151-7.
1999: Angele M K; Knöferl M W; Schwacha M G; Ayala A; Bland K I; Cioffi W G; Josephson S L; Chaudry I H
Hemorrhage decreases macrophage inflammatory protein 2 and interleukin-6 release: a possible mechanism for increased wound infection.
Annals of surgery 1999;229(5):651-60; discussion 660-1.
1999: Song G Y; Chung C S; Schwacha M G; Jarrar D; Chaudry I H; Ayala A
Splenic immune suppression in sepsis: A role for IL-10-induced changes in P38 MAPK signaling.
The Journal of surgical research 1999;83(1):36-43.
1999: Ornan D A; Chaudry I H; Wang P
Pulmonary clearance of adrenomedullin is reduced during the late stage of sepsis.
Biochimica et biophysica acta 1999;1427(2):315-21.
1999: Wang P; Ba Z F; Jarrar D; Cioffi W G; Bland K I; Chaudry I H
Mechanism of adrenal insufficiency following trauma and severe hemorrhage: role of hepatic 11beta-hydroxysteroid dehydrogenase.
Archives of surgery (Chicago, Ill. : 1960) 1999;134(4):394-401.
1999: Catania R A; Schwacha M G; Cioffi W G; Bland K I; Chaudry I H
Does uninjured skin release proinflammatory cytokines following trauma and hemorrhage?
Archives of surgery (Chicago, Ill. : 1960) 1999;134(4):368-73; discussion 373-4.
1999: Ayala A; Xu Y X; Chung C S; Chaudry I H
Does Fas ligand or endotoxin contribute to thymic apoptosis during polymicrobial sepsis?
Shock (Augusta, Ga.) 1999;11(3):211-7.
1999: Zhou M; Chaudry I H; Wang P
Adrenomedullin is upregulated in the heart and aorta during the early and late stages of sepsis.
Biochimica et biophysica acta 1999;1453(2):273-83.
1999: Angele M K; Schwacha M G; Smail N; Catania R A; Ayala A; Cioffi W G; Chaudry I H
Hypoxemia in the absence of blood loss upregulates iNOS expression and activity in macrophages.
The American journal of physiology 1999;276(2 Pt 1):C285-90.
1999: Catania R A; Chaudry I H
Immunological consequences of trauma and shock.
Annals of the Academy of Medicine, Singapore 1999;28(1):120-32.
1999: Samy T S; Schwacha M G; Chung C S; Cioffi W G; Bland K I; Chaudry I H
Proteasome participates in the alteration of signal transduction in T and B lymphocytes following trauma-hemorrhage.
Biochimica et biophysica acta 1999;1453(1):92-104.
1999: Angele M K; Smail N; Ayala A; Cioffi W G; Bland K I; Chaudry I H
L-arginine: a unique amino acid for restoring the depressed macrophage functions after trauma-hemorrhage.
The Journal of trauma 1999;46(1):34-41.
1999: Knöferl M W; Angele M K; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Do different rates of fluid resuscitation adversely or beneficially influence immune responses after trauma-hemorrhage?
The Journal of trauma 1999;46(1):23-33.
1999: Angele M K; Smail N; Knöferl M W; Ayala A; Cioffi W G; Chaudry I H
L-Arginine restores splenocyte functions after trauma and hemorrhage potentially by improving splenic blood flow.
The American journal of physiology 1999;276(1 Pt 1):C145-51.
1998: Wang P; Ba Z F; Cioffi W G; Bland K I; Chaudry I H
Hepatocellular dysfunction after severe hypotension in the absence of blood loss is associated with the increased IL-6 and PGE2.
The Journal of surgical research 1998;80(2):136-42.
1998: Wang P; Ba Z F; Cioffi W G; Bland K I; Chaudry I H
The pivotal role of adrenomedullin in producing hyperdynamic circulation during the early stage of sepsis.
Archives of surgery (Chicago, Ill. : 1960) 1998;133(12):1298-304.
1998: Angele M K; Catania R A; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Dehydroepiandrosterone: an inexpensive steroid hormone that decreases the mortality due to sepsis following trauma-induced hemorrhage.
Archives of surgery (Chicago, Ill. : 1960) 1998;133(12):1281-8.
1998: Schwacha M G; Samy T S; Catania R A; Chaudry I H
Thermal injury alters macrophage responses to prostaglandin E2: contribution to the enhancement of inducible nitric oxide synthase activity.
Journal of leukocyte biology 1998;64(6):740-6.
1998: Chung C S; Xu Y X; Wang W; Chaudry I H; Ayala A
Is Fas ligand or endotoxin responsible for mucosal lymphocyte apoptosis in sepsis?
Archives of surgery (Chicago, Ill. : 1960) 1998;133(11):1213-20.
1998: Molnar R G; Wang P; Chaudry I H
Does neutrophil-mediated oxidative stress play any significant role in producing hepatocellular dysfunction during early sepsis?
The Journal of surgical research 1998;80(1):75-9.
1998: Hahn P Y; Yoo P; Ba Z F; Chaudry I H; Wang P
Upregulation of Kupffer cell beta-adrenoceptors and cAMP levels during the late stage of sepsis.
Biochimica et biophysica acta 1998;1404(3):377-84.
1998: Wang W; Smail N; Wang P; Chaudry I H
Increased gut permeability after hemorrhage is associated with upregulation of local and systemic IL-6.
The Journal of surgical research 1998;79(1):39-46.
1998: Wang P; Zhou M; Ba Z F; Cioffi W G; Chaudry I H
Up-regulation of a novel potent vasodilatory peptide adrenomedullin during polymicrobial sepsis.
Shock (Augusta, Ga.) 1998;10(2):118-22.
1998: Wichmann M W; Ayala A; Chaudry I H
Severe depression of host immune functions following closed-bone fracture, soft-tissue trauma, and hemorrhagic shock.
Critical care medicine 1998;26(8):1372-8.
1998: Angele M K; Smail N; Wang P; Cioffi W G; Bland K I; Chaudry I H
L-arginine restores the depressed cardiac output and regional perfusion after trauma-hemorrhage.
Surgery 1998;124(2):394-401; discussion 401-2.
1998: Chung C S; Xu Y X; Chaudry I H; Ayala A
Sepsis induces increased apoptosis in lamina propria mononuclear cells which is associated with altered cytokine gene expression.
The Journal of surgical research 1998;77(1):63-70.
1998: Angele M K; Ayala A; Cioffi W G; Bland K I; Chaudry I H
Testosterone: the culprit for producing splenocyte immune depression after trauma hemorrhage.
The American journal of physiology 1998;274(6 Pt 1):C1530-6.
1998: Samy T S; Ayala A; Catania R A; Chaudry I H
Trauma-hemorrhage activates signal transduction pathways in mouse splenic T cells.
Shock (Augusta, Ga.) 1998;9(6):443-50.
1998: Remmers D E; Cioffi W G; Bland K I; Wang P; Angele M K; Chaudry I H
Testosterone: the crucial hormone responsible for depressing myocardial function in males after trauma-hemorrhage.
Annals of surgery 1998;227(6):790-9.
1998: Ayala A; Evans T A; Chaudry I H
Does hepatocellular injury in sepsis involve apoptosis?
The Journal of surgical research 1998;76(2):165-73.
1998: Zhou M; Wang P; Chaudry I H
Cardiac contractility and structure are not significantly compromised even during the late, hypodynamic stage of sepsis.
Shock (Augusta, Ga.) 1998;9(5):352-8.
1998: Smail N; Catania R A; Wang P; Cioffi W G; Bland K I; Chaudry I H
Gut and liver: the organs responsible for increased nitric oxide production after trauma-hemorrhage and resuscitation.
Archives of surgery (Chicago, Ill. : 1960) 1998;133(4):399-405.
1998: Smail N; Wang P; Cioffi W G; Bland K I; Chaudry I H
Resuscitation after uncontrolled venous hemorrhage: Does increased resuscitation volume improve regional perfusion?
The Journal of trauma 1998;44(4):701-8.
1998: Wang P; Ba Z F; Cioffi W G; Bland K I; Chaudry I H
Is gut the "motor" for producing hepatocellular dysfunction after trauma and hemorrhagic shock?
The Journal of surgical research 1998;74(2):141-8.
1998: Xu Y X; Ayala A; Chaudry I H
Prolonged immunodepression after trauma and hemorrhagic shock.
The Journal of trauma 1998;44(2):335-41.
1998: Ayala A; Xin Xu Y; Ayala C A; Sonefeld D E; Karr S M; Evans T A; Chaudry I H
Increased mucosal B-lymphocyte apoptosis during polymicrobial sepsis is a Fas ligand but not an endotoxin-mediated process.
Blood 1998;91(4):1362-72.
1998: Wichmann M W; Remmers D; Ayala A; Chaudry I H
[Contribution of soft tissue trauma and/or bone fracture to immune suppression after hemorrhagic shock in the animal experiment]
Der Unfallchirurg 1998;101(1):37-41.
1998: Angele M K; Ayala A; Monfils B A; Cioffi W G; Bland K I; Chaudry I H
Testosterone and/or low estradiol: normally required but harmful immunologically for males after trauma-hemorrhage.
The Journal of trauma 1998;44(1):78-85.
1998: Zellweger R; Wichmann M W; Ayala A; Chaudry I H
Metoclopramide: a novel and safe immunomodulating agent for restoring the depressed macrophage immune function after hemorrhage.
The Journal of trauma 1998;44(1):70-7.
1998: Remmers D E; Wang P; Cioffi W G; Bland K I; Chaudry I H
Chronic resuscitation after trauma-hemorrhage and acute fluid replacement improves hepatocellular function and cardiac output.
Annals of surgery 1998;227(1):112-9.
1998: Wang W; Wang P; Chaudry I H
Pentoxifylline increases gut ketogenesis following trauma and hemorrhagic shock.
Critical care medicine 1998;26(1):101-7.
1997: Molnar R G; Wang P; Ayala A; Ganey P E; Roth R A; Chaudry I H
The role of neutrophils in producing hepatocellular dysfunction during the hyperdynamic stage of sepsis in rats.
The Journal of surgical research 1997;73(2):117-22.
1997: Remmers D E; Wang P; Cioffi W G; Bland K I; Chaudry I H
Testosterone receptor blockade after trauma-hemorrhage improves cardiac and hepatic functions in males.
The American journal of physiology 1997;273(6 Pt 2):H2919-25.
1997: Angele M K; Wichmann M W; Ayala A; Cioffi W G; Chaudry I H
Testosterone receptor blockade after hemorrhage in males. Restoration of the depressed immune functions and improved survival following subsequent sepsis.
Archives of surgery (Chicago, Ill. : 1960) 1997;132(11):1207-14.
1997: Mahmoud M S; Wang P; Chaudry I H
Administration of ATP-MgCl2 following hemorrhage and resuscitation increases hepatic phosphoenolpyruvate carboxykinase and decreases pyruvate kinase activities.
Biochimica et biophysica acta 1997;1336(3):549-56.
1997: Wichmann M W; Ayala A; Chaudry I H
Male sex steroids are responsible for depressing macrophage immune function after trauma-hemorrhage.
The American journal of physiology 1997;273(4 Pt 1):C1335-40.
1997: Wichmann M W; Angele M K; Ayala A; Cioffi W G; Chaudry I H
Flutamide: a novel agent for restoring the depressed cell-mediated immunity following soft-tissue trauma and hemorrhagic shock.
Shock (Augusta, Ga.) 1997;8(4):242-8.
1997: Wang W; Wang P; Chaudry I H
Intestinal alkaline phosphatase: role in the depressed gut lipid transport after trauma-hemorrhagic shock.
Shock (Augusta, Ga.) 1997;8(1):40-4.
1997: Wang W; Wang P; Chaudry I H
Impaired enterocyte triglyceride synthesis after trauma-hemorrhage and resuscitation.
Shock (Augusta, Ga.) 1997;8(1):33-9.
1997: Wang P; Ba Z F; Chaudry I H
Severe hypoxemia in the absence of blood loss depresses hepatocellular function and up-regulates IL-6 and PGE2.
Biochimica et biophysica acta 1997;1361(1):42-8.
1997: Williams T E; Ayala A; Chaudry I H
Inducible macrophage apoptosis following sepsis is mediated by cysteine protease activation and nitric oxide release.
The Journal of surgical research 1997;70(2):113-8.
1997: Xu Y X; Ayala A; Monfils B; Cioffi W G; Chaudry I H
Mechanism of intestinal mucosal immune dysfunction following trauma-hemorrhage: increased apoptosis associated with elevated Fas expression in Peyer's patches.
The Journal of surgical research 1997;70(1):55-60.
1997: Mahmoud M S; Wang P; Chaudry I H
Salutary effects of ATP-MgCl2 on altered hepatocyte signal transduction after hemorrhagic shock.
The American journal of physiology 1997;272(6 Pt 1):G1347-54.
1997: Zhu X H; Zellweger R; Wichmann M W; Ayala A; Chaudry I H
Effects of prolactin and metoclopramide on macrophage cytokine gene expression in late sepsis.
Cytokine 1997;9(6):437-46.
1997: Ayala A; O'Neill P J; Uebele S A; Herdon C D; Chaudry I H
Mechanism of splenic immunosuppression during sepsis: key role of Kupffer cell mediators.
The Journal of trauma 1997;42(5):882-8.
1997: Robinson D A; Wang P; Chaudry I H
Administration of ATP-MgCl2 after trauma-hemorrhage and resuscitation restores the depressed cardiac performance.
The Journal of surgical research 1997;69(1):159-65.
1997: Ayala A; Karr S M; Evans T A; Chaudry I H
Factors responsible for peritoneal granulocyte apoptosis during sepsis.
The Journal of surgical research 1997;69(1):67-75.
1997: Zhou M; Wang P; Chaudry I H
Endothelial nitric oxide synthase is downregulated during hyperdynamic sepsis.
Biochimica et biophysica acta 1997;1335(1-2):182-90.
1997: Wang P; Ba Z F; Chaudry I H
Mechanism of hepatocellular dysfunction during early sepsis. Key role of increased gene expression and release of proinflammatory cytokines tumor necrosis factor and interleukin-6.
Archives of surgery (Chicago, Ill. : 1960) 1997;132(4):364-9; discussion 369-70.
1997: Wang P; Ba Z F; Chaudry I H
Pentoxifylline maintains hepatocellular function and improves cardiac performance during early sepsis.
The Journal of trauma 1997;42(3):429-35; discussion 435-6.
1997: Wang P; Ba Z F; Chaudry I H
Liver endothelial cell function is depressed only during hypodynamic sepsis.
The Journal of surgical research 1997;68(1):38-43.
1997: Xu Y X; Wichmann M W; Ayala A; Cioffi W G; Chaudry I H
Trauma-hemorrhage induces increased thymic apoptosis while decreasing IL-3 release and increasing GM-CSF.
The Journal of surgical research 1997;68(1):24-30.
1997: Zellweger R; Wichmann M W; Ayala A; Stein S; DeMaso C M; Chaudry I H
Females in proestrus state maintain splenic immune functions and tolerate sepsis better than males.
Critical care medicine 1997;25(1):106-10.
1996: Zellweger R; Zhu X H; Wichmann M W; Ayala A; DeMaso C M; Chaudry I H
Prolactin administration following hemorrhagic shock improves macrophage cytokine release capacity and decreases mortality from subsequent sepsis.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(12):5748-54.
1996: Wichmann M W; Zellweger R; DeMaso C M; Ayala A; Chaudry I H
Enhanced immune responses in females, as opposed to decreased responses in males following haemorrhagic shock and resuscitation.
Cytokine 1996;8(11):853-63.
1996: Robinson D A; Wang P; Chaudry I H
Pentoxifylline restores the depressed cardiac performance after trauma-hemorrhage and resuscitation.
The Journal of surgical research 1996;66(1):51-6.
1996: Wang P; Ba Z F; Galardy R E; Chaudry I H
Administration of a matrix metalloproteinase inhibitor after hemorrhage improves cardiovascular and hepatocellular function.
Shock (Augusta, Ga.) 1996;6(5):377-82.
1996: Ayala A; Tu Y; Flye M W; Chaudry I H
Depressed splenic function after hemorrhage results from gastrointestinal tract stimulation of hepatic-mediator release. Correction with portacaval shunt.
Archives of surgery (Chicago, Ill. : 1960) 1996;131(11):1209-14; discussion 1215.
1996: Wichmann M W; Zellweger R; DeMaso C M; Ayala A; Chaudry I H
Mechanism of immunosuppression in males following trauma-hemorrhage. Critical role of testosterone.
Archives of surgery (Chicago, Ill. : 1960) 1996;131(11):1186-91; discussion 1191-2.
1996: Wichmann M W; Haisken J M; Ayala A; Chaudry I H
Melatonin administration following hemorrhagic shock decreases mortality from subsequent septic challenge.
The Journal of surgical research 1996;65(2):109-14.
1996: Wichmann M W; Arnoczky S P; DeMaso C M; Ayala A; Chaudry I H
Depressed osteoblast activity and increased osteocyte necrosis after closed bone fracture and hemorrhagic shock.
The Journal of trauma 1996;41(4):628-33.
1996: Wichmann M W; Zellweger R; DeMaso C M; Ayala A; Williams C; Chaudry I H
Immune function is more compromised after closed bone fracture and hemorrhagic shock than hemorrhage alone.
Archives of surgery (Chicago, Ill. : 1960) 1996;131(9):995-1000.
1996: Wang P; Wood T J; Ba Z F; Chaudry I H
Pentoxifylline maintains vascular endothelial cell function during hyperdynamic and hypodynamic sepsis.
Surgery 1996;120(2):367-73.
1996: Morrison A M; Wang P; Chaudry I H
A novel nonanticoagulant heparin prevents vascular endothelial cell dysfunction during hyperdynamic sepsis.
Shock (Augusta, Ga.) 1996;6(1):46-51.
1996: Wichmann M W; Zellweger R; DeMaso C M; Ayala A; Chaudry I H
Increased melatonin levels after hemorrhagic shock in male and female C3H/HeN mice.
Experientia 1996;52(6):587-90.
1996: Wichmann M W; Zellweger R; DeMaso; Ayala A; Chaudry I H
Melatonin administration attenuates depressed immune functions trauma-hemorrhage.
The Journal of surgical research 1996;63(1):256-62.
1996: Wang P; Ba Z F; Biondo A; Chaudry I
Liver endothelial cell dysfunction occurs early following hemorrhagic shock and persists despite crystalloid resuscitation.
The Journal of surgical research 1996;63(1):241-7.
1996: Zellweger R; Wichmann M W; Ayala A; DeMaso C M; Chaudry I H
Prolactin: a novel and safe immunomodulating hormone for the treatment of immunodepression following severe hemorrhage.
The Journal of surgical research 1996;63(1):53-8.
1996: Wang P; Chaudry I H
Mechanism of hepatocellular dysfunction during hyperdynamic sepsis.
The American journal of physiology 1996;270(5 Pt 2):R927-38.
1996: Ayala A; Chaudry I H
Platelet activating factor and its role in trauma, shock, and sepsis.
New horizons (Baltimore, Md.) 1996;4(2):265-75.
1996: Ayala A; Herdon C D; Lehman D L; Ayala C A; Chaudry I H
Differential induction of apoptosis in lymphoid tissues during sepsis: variation in onset, frequency, and the nature of the mediators.
Blood 1996;87(10):4261-75.
1996: Wang P; Wood T J; Zhou M; Ba Z F; Chaudry I H
Inhibition of the biologic activity of tumor necrosis factor maintains vascular endothelial cell function during hyperdynamic sepsis.
The Journal of trauma 1996;40(5):694-700; discussion 701-1.
1996: Wang P; Ba Z F; Reich S S; Zhou M; Holme K R; Chaudry I H
Effects of nonanticoagulant heparin on cardiovascular and hepatocellular function after hemorrhagic shock.
The American journal of physiology 1996;270(4 Pt 2):H1294-302.
1996: Ayala A; Urbanich M A; Herdon C D; Chaudry I H
Is sepsis-induced apoptosis associated with macrophage dysfunction?
The Journal of trauma 1996;40(4):568-73; discussion 573-4.
1996: Zhu X H; Zellweger R; Ayala A; Chaudry I H
Prolactin inhibits the increased cytokine gene expression in Kupffer cells following haemorrhage.
Cytokine 1996;8(2):134-40.
1996: Ayala A; Chaudry I H
Immune dysfunction in murine polymicrobial sepsis: mediators, macrophages, lymphocytes and apoptosis.
Shock (Augusta, Ga.) 1996;6 Suppl 1():S27-38.
1995: Wang P; Tait S M; Ba Z F; Chaudry I H
Tumor necrosis factor-alpha administration increases Kupffer cell cyclic adenosine monophosphate levels.
Shock (Augusta, Ga.) 1995;4(5):351-5.
1995: Wang P; Ba Z F; Chaudry I H
Endothelium-dependent relaxation is depressed at the macro- and microcirculatory levels during sepsis.
The American journal of physiology 1995;269(5 Pt 2):R988-94.
1995: Ayala A; Deol Z K; Lehman D L; Herdon C D; Chaudry I H
Does endotoxin play a major role in inducing the depression of macrophage function during polymicrobial sepsis?
Archives of surgery (Chicago, Ill. : 1960) 1995;130(11):1178-84; discussion 1184-5.
1995: Hahn P Y; Wang P; Tait S M; Ba Z F; Reich S S; Chaudry I H
Sustained elevation in circulating catecholamine levels during polymicrobial sepsis.
Shock (Augusta, Ga.) 1995;4(4):269-73.
1995: Kerner J; Wang P; Chaudry I H
Impaired gut lipid absorptive capacity after trauma-hemorrhage and resuscitation.
The American journal of physiology 1995;269(4 Pt 2):R869-73.
1995: Zellweger R; Ayala A; Zhu X L; Morrison M H; Chaudry I H
Effect of surgical trauma on splenocyte and peritoneal macrophage immune function.
The Journal of trauma 1995;39(4):645-50.
1995: Zellweger R; Ayala A; Schmand J F; Morrison M H; Chaudry I H
PAF-antagonist administration after hemorrhage-resuscitation prevents splenocyte immunodepression.
The Journal of surgical research 1995;59(3):366-70.
1995: Zellweger R; Ayala A; DeMaso C M; Chaudry I H
Trauma-hemorrhage causes prolonged depression in cellular immunity.
Shock (Augusta, Ga.) 1995;4(2):149-53.
1995: Wang P; Ba Z F; Stepp K J; Chaudry I H
Pentoxifylline attenuates the depressed endothelial cell function and vascular muscle contractility following trauma and hemorrhagic shock.
The Journal of trauma 1995;39(1):121-6; discussion 126-7.
1995: Ertel W; Morrison M H; Ayala A; Chaudry I H
Hypoxemia in the absence of blood loss or significant hypotension causes inflammatory cytokine release.
The American journal of physiology 1995;269(1 Pt 2):R160-6.
1995: Wurster S H; Bonet V; Mayberry A; Hoddinott M; Williams T; Chaudry I H
Intraperitoneal sodium carboxymethylcellulose administration prevents reformation of peritoneal adhesions following surgical lysis.
The Journal of surgical research 1995;59(1):97-102.
1995: Zellweger R; Ayala A; Zhu X L; Holme K R; DeMaso C M; Chaudry I H
A novel nonanticoagulant heparin improves splenocyte and peritoneal macrophage immune function after trauma-hemorrhage and resuscitation.
The Journal of surgical research 1995;59(1):211-8.
1995: Mayberry A; Ayala A; Chaudry I H
Hemorrhage affects the ability of murine peritoneal macrophages to alkanize intracellular pH in acidic environments.
The Journal of surgical research 1995;58(6):682-6.
1995: Tait S M; Wang P; Ba Z F; Chaudry I H
Downregulation of hepatic beta-adrenergic receptors after trauma and hemorrhagic shock.
The American journal of physiology 1995;268(5 Pt 1):G749-53.
1995: Schmand J F; Ayala A; Morrison M H; Chaudry I H
Effects of hydroxyethyl starch after trauma-hemorrhagic shock: restoration of macrophage integrity and prevention of increased circulating interleukin-6 levels.
Critical care medicine 1995;23(5):806-14.
1995: Wang P; Ba Z F; Chaudry I H
ATP-MgCl2 restores depressed endothelial cell function after hemorrhagic shock and resuscitation.
The American journal of physiology 1995;268(4 Pt 2):H1390-6.
1995: Ayala A; Herdon C D; Lehman D L; DeMaso C M; Ayala C A; Chaudry I H
The induction of accelerated thymic programmed cell death during polymicrobial sepsis: control by corticosteroids but not tumor necrosis factor.
Shock (Augusta, Ga.) 1995;3(4):259-67.
1995: Wang P; Ba Z F; Chaudry I H
Hepatocellular dysfunction occurs earlier than the onset of hyperdynamic circulation during sepsis.
Shock (Augusta, Ga.) 1995;3(1):21-6.
1995: Ayala A; Chaudry I H
Dietary n-3 polyunsaturated fatty acid modulation of immune cell function before or after trauma.
Nutrition (Burbank, Los Angeles County, Calif.) 1995;11(1):1-11.
1995: Zhu X L; Zellweger R; Zhu X H; Ayala A; Chaudry I H
Cytokine gene expression in splenic macrophages and Kupffer cells following haemorrhage.
Cytokine 1995;7(1):8-14.
1995: Chaudry I H; Zellweger R; Ayala A
The role of bacterial translocation on Kupffer cell immune function following hemorrhage.
Progress in clinical and biological research 1995;392():209-18.
1994: Schmand J F; Ayala A; Morrison M H; Chaudry I H
Dextran 70 administration after trauma-hemorrhagic shock does not impair cellular immune functions.
Journal of critical care 1994;9(4):244-54.
1994: Ayala A; Lehman D L; Herdon C D; Chaudry I H
Mechanism of enhanced susceptibility to sepsis following hemorrhage. Interleukin-10 suppression of T-cell response is mediated by eicosanoid-induced interleukin-4 release.
Archives of surgery (Chicago, Ill. : 1960) 1994;129(11):1172-8.
1994: Wang P; Ba Z F; Chaudry I H
Nitric oxide. To block or enhance its production during sepsis?
Archives of surgery (Chicago, Ill. : 1960) 1994;129(11):1137-42; discussion 1142-3.
1994: Ertel W; Morrison M H; Ayala A; Chaudry I H
Biological significance of elevated TNF levels: in vivo administration of monoclonal antibody against tnf following haemorrhage shock increases the capacity of macrophages to release TNF while restoring immunoresponsiveness.
Cytokine 1994;6(6):624-32.
1994: Zhu X L; Ayala A; Zellweger R; Morrison M H; Chaudry I H
Peritoneal macrophages show increased cytokine gene expression following haemorrhagic shock.
Immunology 1994;83(3):378-83.
1994: Wang P; Ba Z F; Chaudry I H
Chemically modified heparin improves hepatocellular function, cardiac output, and microcirculation after trauma-hemorrhage and resuscitation.
Surgery 1994;116(2):169-75; discussion 175-6.
1994: Wang P; Tait S M; Ba Z F; Chaudry I H
ATP-MgCl2 administration normalizes macrophage cAMP and beta-adrenergic receptors after hemorrhage and resuscitation.
The American journal of physiology 1994;267(1 Pt 1):G52-8.
1994: Schmand J F; Ayala A; Chaudry I H
Effects of trauma, duration of hypotension, and resuscitation regimen on cellular immunity after hemorrhagic shock.
Critical care medicine 1994;22(7):1076-83.
1994: Mahmoud M S; Wang P; Hootman S R; Reich S S; Chaudry I H
ATP-MgCl2 treatment after trauma-hemorrhage/resuscitation increases hepatocyte P2-purinoceptor binding capacity.
The American journal of physiology 1994;266(6 Pt 2):R1810-5.
1994: Mahmoud M S; Wang P; Hootman S R; Reich S S; Chaudry I H
Downregulation of hepatocyte P2-purinoceptor binding capacity after trauma-hemorrhage/resuscitation.
The American journal of physiology 1994;266(6 Pt 2):R1804-9.
1994: Wang P; Ba Z F; Chaudry I H
Administration of tumor necrosis factor-alpha in vivo depresses endothelium-dependent relaxation.
The American journal of physiology 1994;266(6 Pt 2):H2535-41.
1994: Ayala A; Deol Z K; Lehman D L; Herdon C D; Chaudry I H
Polymicrobial sepsis but not low-dose endotoxin infusion causes decreased splenocyte IL-2/IFN-gamma release while increasing IL-4/IL-10 production.
The Journal of surgical research 1994;56(6):579-85.
1994: Wurster S H; Wang P; Dean R E; Chaudry I H
Vascular smooth muscle contractile function is impaired during early and late stages of sepsis.
The Journal of surgical research 1994;56(6):556-61.
1994: Lindsey H J; Kisala J M; Ayala A; Lehman D; Herdon C D; Chaudry I H
Pentoxifylline attenuates oxygen-induced lung injury.
The Journal of surgical research 1994;56(6):543-8.
1994: Meldrum D R; Ayala A; Chaudry I H
Energetics of lymphocyte "burnout" in late sepsis: adjuvant treatment with ATP-MgCl2 improves energetics and decreases lethality.
The Journal of surgical research 1994;56(6):537-42.
1994: Singh G; Harkema J M; Mayberry A J; Chaudry I H
Severe depression of gut absorptive capacity in patients following trauma or sepsis.
The Journal of trauma 1994;36(6):803-8; discussion 808-9.
1994: Wang P; Ba Z F; Morrison M H; Chaudry I H
Differential alterations in cyclic nucleotide levels in Kupffer cells and hepatocytes following trauma-hemorrhage and resuscitation.
Shock (Augusta, Ga.) 1994;1(6):438-42.
1994: O'Neill P J; Cobb L M; Ayala A; Morrison M H; Chaudry I H
Aggressive fluid resuscitation following intestinal ischemia-reperfusion in immature rats prevents metabolic derangements and down regulates interleukin-6 release.
Shock (Augusta, Ga.) 1994;1(5):381-7.
1994: Ayala A; Chaudry I H
Hemorrhage induces a reduction in the capacity of macrophages to mobilize intracellular calcium secondary to formyl-methionyl-leucyl-phenylalanine stimulation: association with alterations in cells surface Fc receptor expression and increased prostaglandin release.
Shock (Augusta, Ga.) 1994;1(3):228-35.
1994: Wang P; Ba Z F; Lu M C; Ayala A; Harkema J M; Chaudry I H
Measurement of circulating blood volume in vivo after trauma-hemorrhage and hemodilution.
The American journal of physiology 1994;266(2 Pt 2):R368-74.
1994: O'Neill P J; Ayala A; Wang P; Ba Z F; Morrison M H; Schultze A E; Reich S S; Chaudry I H
Role of Kupffer cells in interleukin-6 release following trauma-hemorrhage and resuscitation.
Shock (Augusta, Ga.) 1994;1(1):43-7.
1993: Hemadeh O; Chilukuri S; Bonet V; Hussein S; Chaudry I H
Prevention of peritoneal adhesions by administration of sodium carboxymethyl cellulose and oral vitamin E.
Surgery 1993;114(5):907-10.
1993: Zhu X; Ertel W; Ayala A; Morrison M H; Perrin M M; Chaudry I H
Chloroquine inhibits macrophage tumour necrosis factor-alpha mRNA transcription.
Immunology 1993;80(1):122-6.
1993: Wang P; Ba Z F; Chaudry I H
Endothelial cell dysfunction occurs very early following trauma-hemorrhage and persists despite fluid resuscitation.
The American journal of physiology 1993;265(3 Pt 2):H973-9.
1993: Meldrum D R; Ayala A; Chaudry I H
Mechanism of diltiazem's immunomodulatory effects after hemorrhage and resuscitation.
The American journal of physiology 1993;265(2 Pt 1):C412-21.
1993: Wang P; Ba Z F; Zhou M; Tait S M; Chaudry I H
Pentoxifylline restores cardiac output and tissue perfusion after trauma-hemorrhage and decreases susceptibility to sepsis.
Surgery 1993;114(2):352-8; discussion 358-9.
1993: Ayala A; Meldrum D R; Perrin M M; Chaudry I H
The release of transforming growth factor-beta following haemorrhage: its role as a mediator of host immunosuppression.
Immunology 1993;79(3):479-84.
1993: Wang P; Ayala A; Ba Z F; Zhou M; Perrin M M; Chaudry I H
Tumor necrosis factor-alpha produces hepatocellular dysfunction despite normal cardiac output and hepatic microcirculation.
The American journal of physiology 1993;265(1 Pt 1):G126-32.
1993: Wang P; Ba Z F; Tait S M; Zhou M; Chaudry I H
Alterations in circulating blood volume during polymicrobial sepsis.
Circulatory shock 1993;40(2):92-8.
1993: Singh G; Chaudry K I; Chaudry I H
ATP-MgCl2 restores gut absorptive capacity early after trauma-hemorrhagic shock.
The American journal of physiology 1993;264(5 Pt 2):R977-83.
1993: Singh G; Chaudry K I; Chaudry I H
Restoration of gut absorptive capacity following trauma-hemorrhagic shock by the adjuvant use of heparan sulfate.
The Journal of trauma 1993;34(5):645-51; discussion 651-2.
1993: Wang P; Ba Z F; Chaudry I H
Endothelial cell dysfunction occurs after hemorrhage in nonheparinized but not in preheparinized models.
The Journal of surgical research 1993;54(5):499-506.
1993: Singh G; Chaudry K I; Morrison M H; Chaudry I H
Tumor necrosis factor depresses gut absorptive function.
Circulatory shock 1993;39(4):279-84.
1993: Ertel W; Singh G; Morrison M H; Ayala A; Chaudry I H
Chemically induced hypotension increases PGE2 release and depresses macrophage antigen presentation.
The American journal of physiology 1993;264(4 Pt 2):R655-60.
1993: Wang P; Ba Z F; Burkhardt J; Chaudry I H
Trauma-hemorrhage and resuscitation in the mouse: effects on cardiac output and organ blood flow.
The American journal of physiology 1993;264(4 Pt 2):H1166-73.
1993: Ayala A; Wang P; Chaudry I H
Insights into the mechanism by which interferon-gamma improves macrophage function following hemorrhage and resuscitation.
The Journal of surgical research 1993;54(4):322-7.
1993: O'Neill P J; Cobb L M; Steigman C K; Chaudry I H
Prevention of secondary cardiovascular instability after intestinal ischemia and reperfusion improves survival.
The American journal of physiology 1993;264(3 Pt 2):R622-9.
1993: Kisala J M; Ayala A; Stephan R N; Chaudry I H
A model of pulmonary atelectasis in rats: activation of alveolar macrophage and cytokine release.
The American journal of physiology 1993;264(3 Pt 2):R610-4.
1993: Singh G; Chaudry K I; Chaudry I H
Diltiazem reduces whole blood viscosity following trauma-hemorrhagic shock and resuscitation.
Circulatory shock 1993;39(3):231-6.
1993: Ayala A; Knotts J B; Ertèl W; Perrin M M; Morrison M H; Chaudry I H
Role of interleukin 6 and transforming growth factor-beta in the induction of depressed splenocyte responses following sepsis.
Archives of surgery (Chicago, Ill. : 1960) 1993;128(1):89-94; discussion 94-5.
1993: Ertel W; Morrison M H; Ayala A; Chaudry I H
Modulation of macrophage membrane phospholipids by n-3 polyunsaturated fatty acids increases interleukin 1 release and prevents suppression of cellular immunity following hemorrhagic shock.
Archives of surgery (Chicago, Ill. : 1960) 1993;128(1):15-20; discussion 20-1.
1993: Blank M L; O'Neill P J; Steigman C K; Cobb L M; Wilde R A; Havenstein P J; Chaudry I H
Reperfusion injury following testicular torsion and detorsion in prepubertal rats.
Urological research 1993;21(6):389-93.
1992: Wang P; Ba Z F; Chaudry I H
Differential effects of ATP-MgCl2 on portal and hepatic arterial blood flow after hemorrhage and resuscitation.
The American journal of physiology 1992;263(6 Pt 1):G895-900.
1992: Milsom J W; Senagore A; Walshaw R K; Mostosky U V; Wang P; Johnson W; Chaudry I H
Preoperative radiation therapy produces an early and persistent reduction in colorectal anastomotic blood flow.
The Journal of surgical research 1992;53(5):464-9.
1992: Wang P; Ba Z F; Morrison M H; Ayala A; Chaudry I H
Mechanism of the beneficial effects of pentoxifylline on hepatocellular function after trauma hemorrhage and resuscitation.
Surgery 1992;112(2):451-7; discussion 457-8.
1992: Meldrum D R; Ayala A; Chaudry I H
Energetics of defective macrophage antigen presentation after hemorrhage as determined by ultraresolution 31P nuclear magnetic resonance spectrometry: restoration with adenosine triphosphate-MgCl2.
Surgery 1992;112(2):150-6; discussion 156-8.
1992: Singh G; Chaudry K I; Chudler L C; Chaudry I H
Sepsis produces early depression of gut absorptive capacity: restoration with diltiazem treatment.
The American journal of physiology 1992;263(1 Pt 2):R19-23.
1992: Wang P; Zhou M; Rana M W; Ba Z F; Chaudry I H
Differential alterations in microvascular perfusion in various organs during early and late sepsis.
The American journal of physiology 1992;263(1 Pt 1):G38-43.
1992: Ertel W; Morrison M H; Meldrum D R; Ayala A; Chaudry I H
Ibuprofen restores cellular immunity and decreases susceptibility to sepsis following hemorrhage.
The Journal of surgical research 1992;53(1):55-61.
1992: Ayala A; Perrin M M; Wang P; Chaudry I H
Sepsis induces an early increased spontaneous release of hepatocellular stimulatory factor (interleukin-6) by Kupffer cells in both endotoxin tolerant and intolerant mice.
The Journal of surgical research 1992;52(6):635-41.
1992: Wang P; Ba Z F; Meldrum D R; Chaudry I H
Diltiazem restores cardiac output and improves renal function after hemorrhagic shock and crystalloid resuscitation.
The American journal of physiology 1992;262(5 Pt 2):H1435-40.
1992: Wang P; Ba Z F; Chaudry I H
ATP-MgCl2 restores the depressed cardiac output following trauma and severe hemorrhage even in the absence of blood resuscitation.
Circulatory shock 1992;36(4):277-83.
1992: Wang P; Ba Z F; Morrison M H; Ayala A; Dean R E; Chaudry I H
Mechanism of the beneficial effects of ATP-MgCl2 following trauma-hemorrhage and resuscitation: downregulation of inflammatory cytokine (TNF, IL-6) release.
The Journal of surgical research 1992;52(4):364-71.
1992: Rana M W; Singh G; Wang P; Ayala A; Zhou M; Chaudry I H
Protective effects of preheparinization on the microvasculature during and after hemorrhagic shock.
The Journal of trauma 1992;32(4):420-6.
1992: Singh G; Chaudry K I; Chaudry I H
Crystalloid is as effective as blood in the resuscitation of hemorrhagic shock.
Annals of surgery 1992;215(4):377-82.
1992: Ayala A; Perrin M M; Kisala J M; Ertel W; Chaudry I H
Polymicrobial sepsis selectively activates peritoneal but not alveolar macrophages to release inflammatory mediators (interleukins-1 and -6 and tumor necrosis factor).
Circulatory shock 1992;36(3):191-9.
1992: Wang P; Zhou M; Rana M W; Singh G; Ba Z F; Ayala A; Chaudry I H
ATP-MgCl2 restores renal microcirculation following trauma and severe hemorrhage.
Canadian journal of physiology and pharmacology 1992;70(3):349-57.
1992: Wang P; Ba Z F; Ayala A; Chaudry I H
Hepatocellular dysfunction persists during early sepsis despite increased volume of crystalloid resuscitation.
The Journal of trauma 1992;32(3):389-96; discussion 396-7.
1992: Harkema J M; Chaudry I H
Magnesium-adenosine triphosphate in the treatment of shock, ischemia, and sepsis.
Critical care medicine 1992;20(2):263-75.
1992: Ertel W; Morrison M H; Ayala A; Dean R E; Chaudry I H
Interferon-gamma attenuates hemorrhage-induced suppression of macrophage and splenocyte functions and decreases susceptibility to sepsis.
Surgery 1992;111(2):177-87.
1992: Ayala A; Kisala J M; Felt J A; Perrin M M; Chaudry I H
Does endotoxin tolerance prevent the release of inflammatory monokines (interleukin 1, interleukin 6, or tumor necrosis factor) during sepsis?
Archives of surgery (Chicago, Ill. : 1960) 1992;127(2):191-6; discussion 196-7.
1992: Ertel W; Morrison M H; Ayala A; Chaudry I H
Chloroquine attenuates hemorrhagic shock-induced immunosuppression and decreases susceptibility to sepsis.
Archives of surgery (Chicago, Ill. : 1960) 1992;127(1):70-5; discussion 75-6.
1992: Wang P; Ba Z F; Burkhardt J; Chaudry I H
Measurement of hepatic blood flow after severe hemorrhage: lack of restoration despite adequate resuscitation.
The American journal of physiology 1992;262(1 Pt 1):G92-8.
1992: Ayala A; Perrin M M; Ertel W; Chaudry I H
Differential effects of hemorrhage on Kupffer cells: decreased antigen presentation despite increased inflammatory cytokine (IL-1, IL-6 and TNF) release.
Cytokine 1992;4(1):66-75.
1991: Ayala A; Perrin M M; Wang P; Ertel W; Chaudry I H
Hemorrhage induces enhanced Kupffer cell cytotoxicity while decreasing peritoneal or splenic macrophage capacity. Involvement of cell-associated tumor necrosis factor and reactive nitrogen.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(12):4147-54.
1991: Wang P; Ba Z F; Chaudry I H
Increase in hepatic blood flow during early sepsis is due to increased portal blood flow.
The American journal of physiology 1991;261(6 Pt 2):R1507-12.
1991: Singh G; Chaudry K I; Chudler L C; Chaudry I H
Depressed gut absorptive capacity early after trauma-hemorrhagic shock. Restoration with diltiazem treatment.
Annals of surgery 1991;214(6):712-8.
1991: Singh G; Chaudry K I; Chudler L C; O'Neill P J; Chaudry I H
Measurement of D-xylose gut absorptive capacity in conscious rats.
The American journal of physiology 1991;261(5 Pt 2):R1313-20.
1991: Ertel W; Morrison M H; Ayala A; Chaudry I H
Chloroquine attenuates hemorrhagic shock-induced suppression of Kupffer cell antigen presentation and major histocompatibility complex class II antigen expression through blockade of tumor necrosis factor and prostaglandin release.
Blood 1991;78(7):1781-8.
1991: Ertel W; Morrison M H; Ayala A; Perrin M M; Chaudry I H
Anti-TNF monoclonal antibodies prevent haemorrhage-induced suppression of Kupffer cell antigen presentation and MHC class II antigen expression.
Immunology 1991;74(2):290-7.
1991: Meldrum D R; Ayala A; Perrin M M; Ertel W; Chaudry I H
Diltiazem restores IL-2, IL-3, IL-6, and IFN-gamma synthesis and decreases host susceptibility to sepsis following hemorrhage.
The Journal of surgical research 1991;51(2):158-64.
1991: Meldrum D R; Ayala A; Wang P; Ertel W; Chaudry I H
Association between decreased splenic ATP levels and immunodepression: amelioration with ATP-MgCl2.
The American journal of physiology 1991;261(2 Pt 2):R351-7.
1991: Ertel W; Morrison M H; Wang P; Ba Z F; Ayala A; Chaudry I H
The complex pattern of cytokines in sepsis. Association between prostaglandins, cachectin, and interleukins.
Annals of surgery 1991;214(2):141-8.
1991: Ertel W; Morrison M H; Ayala A; Chaudry I H
Insights into the mechanisms of defective antigen presentation after hemorrhage.
Surgery 1991;110(2):440-5; discussion 445-7.
1991: Wang P; Ba Z F; Dean R E; Chaudry I H
Diltiazem administration after crystalloid resuscitation restores active hepatocellular function and hepatic blood flow after severe hemorrhagic shock.
Surgery 1991;110(2):390-6; discussion 396-7.
1991: Ertel W; Morrison M H; Ayala A; Chaudry I H
Eicosanoids regulate tumor necrosis factor synthesis after hemorrhage in vitro and in vivo.
The Journal of trauma 1991;31(5):609-15; discussion 615-6.
1991: Wang P; Ayala A; Dean R E; Hauptman J G; Ba Z F; DeJong G K; Chaudry I H
Adequate crystalloid resuscitation restores but fails to maintain the active hepatocellular function following hemorrhagic shock.
The Journal of trauma 1991;31(5):601-7; discussion 607-8.
1991: Wang P; Ba Z F; Dean R E; Chaudry I H
ATP-MgCl2 restores the depressed hepatocellular function and hepatic blood flow following hemorrhage and resuscitation.
The Journal of surgical research 1991;50(4):368-74.
1991: Ertel W; Morrison M H; Ayala A; Perrin M M; Chaudry I H
Blockade of prostaglandin production increases cachectin synthesis and prevents depression of macrophage functions after hemorrhagic shock.
Annals of surgery 1991;213(3):265-71.
1991: Wang P; Ba Z F; Chaudry I H
Hepatic extraction of indocyanine green is depressed early in sepsis despite increased hepatic blood flow and cardiac output.
Archives of surgery (Chicago, Ill. : 1960) 1991;126(2):219-24.
1991: Wang P; Chaudry I H
Crystalloid resuscitation restores but does not maintain cardiac output following severe hemorrhage.
The Journal of surgical research 1991;50(2):163-9.
1991: Hauptman J G; Wang P; DeJong G K; Chaudry I H
Improved methodology for the evaluation of the velocity of clearance of indocyanine green in the rat.
Circulatory shock 1991;33(1):26-32.
1991: Ayala A; Wang P; Ba Z F; Perrin M M; Ertel W; Chaudry I H
Differential alterations in plasma IL-6 and TNF levels after trauma and hemorrhage.
The American journal of physiology 1991;260(1 Pt 2):R167-71.
1990: Wang P; Hauptman J G; Chaudry I H
Hemorrhage produces depression in microvascular blood flow which persists despite fluid resuscitation.
Circulatory shock 1990;32(4):307-18.
1990: Rana M W; Ayala A; Dean R E; Chaudry I H
Decreased Fc receptor expression on macrophages following simple hemorrhage as observed by scanning immunoelectron microscopy.
Journal of leukocyte biology 1990;48(6):512-8.
1990: Wang P; Singh G; Rana M W; Ba Z F; Chaudry I H
Preheparinization improves organ function after hemorrhage and resuscitation.
The American journal of physiology 1990;259(3 Pt 2):R645-50.
1990: Ertel W; Meldrum D R; Morrison M H; Ayala A; Chaudry I H
Immunoprotective effect of a calcium channel blocker on macrophage antigen presentation function, major histocompatability class II antigen expression, and interleukin-1 synthesis after hemorrhage.
Surgery 1990;108(2):154-9; discussion 159-60.
1990: Ayala A; Perrin M M; Chaudry I H
Defective macrophage antigen presentation following haemorrhage is associated with the loss of MHC class II (Ia) antigens.
Immunology 1990;70(1):33-9.
1990: Wang P; Hauptman J G; Chaudry I H
Hepatocellular dysfunction occurs early after hemorrhage and persists despite fluid resuscitation.
The Journal of surgical research 1990;48(5):464-70.
1990: Ayala A; Perrin M M; Meldrum D R; Ertel W; Chaudry I H
Hemorrhage induces an increase in serum TNF which is not associated with elevated levels of endotoxin.
Cytokine 1990;2(3):170-4.
1990: Ayala A; Perrin M M; Wagner M A; Chaudry I H
Enhanced susceptibility to sepsis after simple hemorrhage. Depression of Fc and C3b receptor-mediated phagocytosis.
Archives of surgery (Chicago, Ill. : 1960) 1990;125(1):70-4; discussion 74-5.
1990: Chaudry I H
Use of ATP following shock and ischemia.
Annals of the New York Academy of Sciences 1990;603():130-40; discussion 140-1.
1989: Hauptman J G; DeJong G K; Blasko K A; Chaudry I H
Measurement of hepatocellular function, cardiac output, effective blood volume, and oxygen saturation in rats.
The American journal of physiology 1989;257(2 Pt 2):R439-44.
1989: Stephan R N; Ayala A; Harkema J M; Dean R E; Border J R; Chaudry I H
Mechanism of immunosuppression following hemorrhage: defective antigen presentation by macrophages.
The Journal of surgical research 1989;46(6):553-6.
1989: Chaudry I H
ATP-MgCl2 and liver blood flow following shock and ischemia.
Progress in clinical and biological research 1989;299():19-31.
1988: Harkema J M; Gorman M W; Bieber L L; Chaudry I H
Metabolic interaction between skeletal muscle and liver during bacteremia.
Archives of surgery (Chicago, Ill. : 1960) 1988;123(11):1415-9.
1988: Stephan R N; Conrad P J; Saizawa M; Dean R E; Chaudry I H
Prostaglandin E2 depresses antigen-presenting cell function of peritoneal macrophages.
The Journal of surgical research 1988;44(6):733-9.
1988: Stephan R N; Kisala J M; Dean R E; Geha A S; Chaudry I H
Effect of blood transfusion on antigen presentation function and on interleukin 2 generation.
Archives of surgery (Chicago, Ill. : 1960) 1988;123(2):235-40.
1988: Chaudry I H; Stephan R N; Dean R E; Clemens M G; Baue A E
Use of magnesium-ATP following liver ischemia.
Magnesium 1988;7(2):68-77.
1987: Stephan R N; Saizawa M; Conrad P J; Dean R E; Geha A S; Chaudry I H
Depressed antigen presentation function and membrane interleukin-1 activity of peritoneal macrophages after laparotomy.
Surgery 1987;102(2):147-54.
1987: Stephan R N; Kupper T S; Geha A S; Baue A E; Chaudry I H
Hemorrhage without tissue trauma produces immunosuppression and enhances susceptibility to sepsis.
Archives of surgery (Chicago, Ill. : 1960) 1987;122(1):62-8.

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