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Kazuaki Chayama

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Takayasu Kuwabara; Shiro Oka; Fumio Shimamoto; Shinji Tanaka; Yuji Urabe; Masaharu Yoshihara; Koji Arihiro; Toru Hiyama; Kazuaki Chayama
Response.
Tatsuya Maruhashi; Takeshi Matsumoto; Shinsuke Mikami; Ayumu Nakashima; Kensuke Noma; Junko Soga; Kazuaki Chayama; Noritaka Fujimura; Chikara Goto; Takayuki Hidaka; Naomi Idei; Yumiko Iwamoto; Masato Kajikawa; Yasuki Kihara; Yukihito Higashi
Nitroglycerine-induced vasodilation for assessment of vascular function: a comparison with flow-mediated vasodilation.
Shiro Oka; Shinji Tanaka; Hiroyuki Kanao; Koichi Nakadoi; Kazuaki Chayama
Risk analysis of submucosal invasive rectal carcinomas for lymph node metastasis to expand indication criteria for endoscopic resection.

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2013: Takayasu Kuwabara; Shiro Oka; Fumio Shimamoto; Shinji Tanaka; Yuji Urabe; Masaharu Yoshihara; Koji Arihiro; Toru Hiyama; Kazuaki Chayama
Response.
Gastrointestinal endoscopy 2013;77(6):973-4.
2013: Tatsuya Maruhashi; Takeshi Matsumoto; Shinsuke Mikami; Ayumu Nakashima; Kensuke Noma; Junko Soga; Kazuaki Chayama; Noritaka Fujimura; Chikara Goto; Takayuki Hidaka; Naomi Idei; Yumiko Iwamoto; Masato Kajikawa; Yasuki Kihara; Yukihito Higashi
Nitroglycerine-induced vasodilation for assessment of vascular function: a comparison with flow-mediated vasodilation.
Arteriosclerosis, thrombosis, and vascular biology 2013;33(6):1401-8.
2013: Shiro Oka; Shinji Tanaka; Hiroyuki Kanao; Koichi Nakadoi; Kazuaki Chayama
Risk analysis of submucosal invasive rectal carcinomas for lymph node metastasis to expand indication criteria for endoscopic resection.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2013;25 Suppl 2():21-5.
2013: Keiko Arataki; Hiromi Abe; Hiroshi Aikata; Sakura Akamatsu; Rie Akiyama; C Nelson Hayes; Nobuhiko Hiraga; Michio Imamura; Hiroiku Kawakami; Tomokazu Kawaoka; Daiki Miki; Hidenori Ochi; Waka Ohishi; Shoichi Takahashi; Masataka Tsuge; Kazuaki Chayama
Circulating microRNA-22 correlates with microRNA-122 and represents viral replication and liver injury in patients with chronic hepatitis B.
Journal of medical virology 2013;85(5):789-98.
2013: Rie Miyaki; Shiro Oka; Bisser Raytchev; Yoji Sanomura; Toru Tamaki; Shinji Tanaka; Shigeto Yoshida; Masaharu Yoshihara; Kazufumi Kaneda; Tetsushi Koide; Yoko Kominami; Taiji Matsuo; Kazuaki Chayama
Quantitative identification of mucosal gastric cancer under magnifying endoscopy with flexible spectral imaging color enhancement.
Journal of gastroenterology and hepatology 2013;28(5):841-7.
2013: Yuji Urabe; Hiromi Abe; Kazuaki Chayama; Naoya Hosono; Naoyuki Kamatani; Naoya Kato; Kazuhiko Koike; Michiaki Kubo; Hiromitsu Kumada; Vinod Kumar; Paulisally Hau Yi Lo; Daiki Miki; Ryosuke Muroyama; Yusuke Nakamura; Hidenori Ochi; Masao Omata; Motoyuki Otsuka; Atsushi Takahashi; Chizu Tanikawa; Ryosuke Tateishi; Joji Toyota; Koichi Matsuda
A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.
Journal of hepatology 2013;58(5):875-82.
2013: Taiki Aoyama; Hiroshi Aikata; Noriaki Naeshiro; Makoto Nakano; Shiro Oka; Shinji Tanaka; Ikue Watari; Shigeto Yoshida; Kazuaki Chayama
Small bowel abnormalities in patients with compensated liver cirrhosis.
Digestive diseases and sciences 2013;58(5):1390-6.
2013: Kazuyoshi Suenari; Takehito Tokuyama; Shigeyuki Ueda; Kazuaki Chayama; Mai Fujiwara; Yukoh Hirai; Kenta Kajihara; Yuko Makita; Chikaaki Motoda; Yukiko Nakano; Noboru Oda; Hiroshi Ogi; Yasuki Kihara
Left atrial thickness under the catheter ablation lines in patients with paroxysmal atrial fibrillation: insights from 64-slice multidetector computed tomography.
Heart and vessels 2013;28(3):360-8.
2013: Yoichi Hamai; Jun Hihara; Ichiko Kishimoto; Yoshie Kobayashi; Yoshihiro Miyata; Hiroshi Aikata; Yoshiro Aoki; Kazuaki Chayama; Junya Taomoto; Morihito Okada
Airway stenting for tracheal obstruction due to lymph node metastasis of hepatocellular carcinoma.
Anticancer research 2013;33(4):1761-4.
2013: Kazuaki Chayama; C Nelson Hayes; Waka Ohishi; Yoshiiku Kawakami
Response to "Treatment guidelines for HCV genotype 1: mono for low, triple for high, and dual for 'middle'?".
Journal of gastroenterology 2013;48(4):557-8.
2013: Sayaka Takata; Shinji Tanaka; Motomi Terasaki; Shigeto Yoshida; Nana Hayashi; Hiroyuki Kanao; Koichi Nakadoi; Shiro Oka; Kazuaki Chayama
Characteristic magnifying narrow-band imaging features of colorectal tumors in each growth type.
International journal of colorectal disease 2013;28(4):459-68.
2013: Shinji Tanaka; Nana Hayashi; Shiro Oka; Kazuaki Chayama
Endoscopic assessment of colorectal cancer with superficial or deep submucosal invasion using magnifying colonoscopy.
Clinical endoscopy 2013;46(2):138-46.
2013: Yoko Kominami; Daiki Miki; Daisuke Miyaki; Eisuke Murakami; Noriaki Naeshiro; Yuko Nagaoki; Takashi Nakahara; Tamito Sasaki; Masahiro Serikawa; Shoichi Takahashi; Shintaro Takaki; Mio Tanaka; Masataka Tsuge; Nobuhiko Hiraga; Ken Hiramatsu; Yoji Honda; Hideyuki Hyogo; Michio Imamura; Yoshiiku Kawakami; Tomokazu Kawaoka; Hiroshi Aikata; Kazuaki Chayama
[A case of clonorchiasis complicated with the expansion of liver cyst].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2013;110(3):456-64.
2013: Jouji Toyota; Ichimaro Yamada; Itaru Ozeki; F Suzuki; Y Suzuki; S Takahashi; K Aoki; Y Asahina; Kazuaki Chayama; N Izumi; N Kamiya; Yoshiyasu Karino; Y Kawakami; H Kumada
Virological response and safety of 24-week telaprevir alone in Japanese patients infected with hepatitis C virus subtype 1b.
Journal of viral hepatitis 2013;20(3):167-73.
2013: Shinji Tanaka; Motomi Terasaki; Nana Hayashi; Shiro Oka; Kazuaki Chayama
Warning for unprincipled colorectal endoscopic submucosal dissection: accurate diagnosis and reasonable treatment strategy.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2013;25(2):107-16.
2013: Yohji Honda; Masaki Ishikawa; Hideaki Kakizawa; Tomokazu Kawaoka; Masahiro Kenjo; Tomoki Kimura; Tomoki Kobayashi; Keiichi Masaki; Daisuke Miyaki; Noriaki Naeshiro; Yuko Nagaoki; Yasushi Nagata; Takashi Nakahara; Atsushi Ono; Shoichi Takahashi; Shintaro Takaki; Hiroshi Aikata; Kazuo Awai; Takayuki Fukuhara; Akira Hiramatsu; Kazuaki Chayama
Stereotactic body radiation therapy combined with transcatheter arterial chemoembolization for small hepatocellular carcinoma.
Journal of gastroenterology and hepatology 2013;28(3):530-6.
2013: Akemi Takamura; Shinji Tanaka; Masaharu Yoshihara; Tomoyuki Boda; Masanori Ito; Yoko Matsumoto; Kazuaki Chayama
High expression of gastrin receptor protein in injured mucosa of Helicobacter pylori-positive gastritis.
Digestive diseases and sciences 2013;58(3):634-40.
2013: Yizhou Zhang; Hidenori Ochi; Shoichi Takahashi; Akiko Tasaka; Tadahiko Yoshima; Kazuaki Chayama
Involvement of microRNA-224 in cell proliferation, migration, invasion, and anti-apoptosis in hepatocellular carcinoma.
Journal of gastroenterology and hepatology 2013;28(3):565-75.
2013: Namiki Izumi; Eiji Kajiwara; Kazuya Kariyama; Shinji Katsushima; Tsutomu Kawai; Masatoshi Kudo; Hiroshi Adachi; Yasuhiro Asahina; Kazuaki Chayama; Yoichi Hiasa; Mie Inao; Masayuki Kurosaki; Hisataka Moriwaki; Yukishige Okamura; Makoto Oketani; Kouichi Takaguchi; Takayuki Takeuchi; Eiji Tanaka; Joji Toyoda; Gotaro Yamada; Hiroshi Yatsuhashi; Osamu Yokosuka; Hiromitsu Kumada
Inhibition of hepatocellular carcinoma by PegIFNα-2a in patients with chronic hepatitis C: a nationwide multicenter cooperative study.
Journal of gastroenterology 2013;48(3):382-90.
2013: Hirotaka Tashiro; Hirofumi Tazawa; Takashi Onoe; Shoichi Takahashi; Hiroshi Aikata; Hironobu Amano; Kazuaki Chayama; Kentaro Ide; Kohei Ishiyama; Tsuyoshi Kobayashi; Hirotaka Kono; Shintaro Kuroda; Hideki Ohdan
Surgical treatment for portosystemic encephalopathy in patients with liver cirrhosis: Occlusion of portosystemic shunt in combination with splenectomy.
Hepatology research : the official journal of the Japan Society of Hepatology 2013;43(3):249-54.
2013: Kei Shinagawa; Tomonori Sumida; Miwako Tanaka; Shinji Tanaka; Wataru Yasui; Yukihito Higashi; Yasuhiko Kitadai; Eiji Ohara; Mayu Ohnishi; Mieko Onoyama; Kazuaki Chayama
Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer.
International journal of cancer. Journal international du cancer 2013;132(4):813-23.
2013: Makoto Higashimaya; Norifumi Numata; Shiro Oka; Yoji Sanomura; Shinji Tanaka; Shigeto Yoshida; Koji Arihiro; Kazuaki Chayama
Endoscopic submucosal dissection for residual early gastric cancer after endoscopic submucosal dissection.
Gastrointestinal endoscopy 2013;77(2):298-302.
2013: Paulisally Hau Yi Lo; Kazuaki Chayama; Naoya Kato; Kazuhiko Koike; Michiaki Kubo; Vinod Kumar; Daiki Miki; Yusuke Nakamura; Chizu Tanikawa; Yuji Urabe; Koichi Matsuda
Identification of a Functional Variant in the MICA Promoter Which Regulates MICA Expression and Increases HCV-Related Hepatocellular Carcinoma Risk.
PloS one 2013;8(4):e61279.
2013: Nana Hayashi; Hiroyuki Kanao; Shiro Oka; Shinji Tanaka; Shigeto Yoshida; Kazuaki Chayama
Relationship between narrow-band imaging magnifying observation and pit pattern diagnosis in colorectal tumors.
Digestion 2013;87(1):53-8.
2013: Yuichi Fujii; Noritaka Fujimura; Chikara Goto; Takayuki Hidaka; Kazuaki Chayama; Naomi Idei; Yumiko Iwamoto; Yasuki Kihara; Tatsuya Maruhashi; Shinsuke Mikami; Ayumu Nakashima; Kensuke Noma; Junko Soga; Hiroki Teragawa; Yukihito Higashi
Flow-mediated vasodilation and anatomical variation of the brachial artery (double brachial artery) in healthy subjects and patients with cardiovascular disease.
Circulation journal : official journal of the Japanese Circulation Society 2013;77(4):1073-80.
2013: Kazuaki Chayama; C Nelson Hayes; Waka Ohishi; Yoshiiku Kawakami
Treatment of chronic hepatitis C virus infection in Japan: update on therapy and guidelines.
Journal of gastroenterology 2013;48(1):1-12.
2013: Rikita Nakano; Hidenori Ochi; Tatsuhiko Tsunoda; Hiromi Abe; Yasufumi Hayashida; Naoyuki Kamatani; Hiromitsu Kumada; Toshiro Maekawa; Yusuke Nakamura; Kazuaki Chayama
Single-nucleotide polymorphisms in GALNT8 are associated with the response to interferon therapy for chronic hepatitis C.
The Journal of general virology 2013;94(Pt 1):81-9.
2012: Takayasu Kuwabara; Shiro Oka; Fumio Shimamoto; Shinji Tanaka; Yuji Urabe; Masaharu Yoshihara; Koji Arihiro; Toru Hiyama; Kazuaki Chayama
Clinical features of pharyngeal intraepithelial neoplasias and outcomes of treatment by endoscopic submucosal dissection.
Gastrointestinal endoscopy 2012;76(6):1095-103.
2012: Daisuke Miyaki; Noriaki Naeshiro; Yuko Nagaoki; Takashi Nakahara; Shoichi Takahashi; Shintaro Takaki; Mio Tanaka; Koji Waki; Akira Hiramatsu; Yohji Honda; Masaki Ishikawa; Hideaki Kakizawa; Tomokazu Kawaoka; Hiroshi Aikata; Kazuo Awai; Kazuaki Chayama
Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma according to Child-Pugh classification.
Journal of gastroenterology and hepatology 2012;27(12):1850-7.
2012: Hideyuki Hyogo; Tomokazu Ishitobi; Yuki Kimura; Sayaka Maeda; Sho-ichi Yamagishi; Kazuaki Chayama
Serum levels of pigment epithelium-derived factor (PEDF) are independently associated with procollagen III N-terminal peptide levels in patients with nonalcoholic fatty liver disease.
Clinical biochemistry 2012;45(18):1554-7.
2012: Shintaro Yanagimoto; Hiroshi Yotsuyanagi; Kyoji Moriya; Junki Takamatsu; Kunihisa Tsukada; Kazuaki Chayama; Shuhei Hige; Michio Kato; Yoshimi Kikuchi; Kazuhiko Koike
Chronic hepatitis B in patients coinfected with human immunodeficiency virus in Japan: a retrospective multicenter analysis.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2012;18(6):883-90.
2012: Masana Tatsugami; Masaharu Yoshihara; Ken Haruma; Masanori Ito; Hirofumi Matsui; Shinji Tanaka; Kazuaki Chayama
Bile acid promotes intestinal metaplasia and gastric carcinogenesis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2012;21(11):2101-7.
2012: Hideyuki Hyogo; Tomokazu Ishitobi; Yuki Kimura; Sayaka Maeda; Sho-ichi Yamagishi; Kazuaki Chayama
Increased insulinogenic index is an independent determinant of nonalcoholic fatty liver disease activity score in patients with normal glucose tolerance.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2012;44(11):935-9.
2012: Takashi Nakahara; Shoichi Takahashi; Hiroshi Aikata; Koji Arihiro; Hideyuki Hyogo; Tomokazu Ishitobi; Yuki Kimura; Kazuaki Chayama
Efficacy of rosuvastatin for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label, pilot study.
Hepatology research : the official journal of the Japan Society of Hepatology 2012;42(11):1065-72.
2012: Masanori Ito; Taiji Matsuo; Shinji Tanaka; Kazuaki Chayama
[Characteristics of H. pylori-negative gastric cancer].
Nihon rinsho. Japanese journal of clinical medicine 2012;70(10):1802-6.
2012: Shiro Oka; Yoji Sanomura; Shinji Tanaka; Norifumi Numata; Kazuaki Chayama
[Endoscopic diagnosis of early gastric cancer].
Nihon rinsho. Japanese journal of clinical medicine 2012;70(10):1742-7.
2012: Takuji Okusaka; Hidetugu Saito; Isao Sakaida; Michio Sata; Toshihito Seki; Yasukazu Shioyama; Keiko Shiratori; Katsuaki Tanaka; Takuya Tsutsumi; Masaharu Yoshikawa; Kazuaki Chayama; Naoaki Hayashi; Masao Honda; Hiroshi Ishii; Hiroshi Kasugai; Masatoshi Kudo; Hiromitsu Kumada; Yukio Kusumoto; Kiwamu Okita; Kenji Sakata
A randomized phase II trial of intra-arterial chemotherapy using SM-11355 (Miriplatin) for hepatocellular carcinoma.
Investigational new drugs 2012;30(5):2015-25.
2012: Yumiko Iwamoto; Masato Kajikawa; Yasuki Kihara; Tatsuya Maruhashi; Takeshi Matsumoto; Shinsuke Mikami; Ayumu Nakashima; Kensuke Noma; Kazuaki Chayama; Yuichi Fujii; Noritaka Fujimura; Naomi Idei; Yukihito Higashi
Intima-media thickness of brachial artery, vascular function, and cardiovascular risk factors.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(9):2295-303.
2012: Kazuaki Chayama; C Nelson Hayes; Michio Imamura
Impact of interleukin-28B genotype on in vitro and in vivo systems of hepatitis C virus replication.
Hepatology research : the official journal of the Japan Society of Hepatology 2012;42(9):841-53.
2012: Tomokazu Kawaoka; Daiki Miki; Hidenori Ochi; Hideki Ohdan; Takashi Onoe; Shoichi Takahashi; Shintaro Takaki; Hirotaka Tashiro; Masataka Tsuge; Koji Waki; Nobuhiko Hiraga; Akira Hiramatsu; Michio Imamura; Yoshiiku Kawakami; Hiroshi Aikata; Kazuaki Chayama
Interleukin-28B single nucleotide polymorphism of donors and recipients can predict viral response to pegylated interferon/ribavirin therapy in patients with recurrent hepatitis C after living donor liver transplantation.
Journal of gastroenterology and hepatology 2012;27(9):1467-72.
2012: Koichi Kagawa; Yoshiiku Kawakami; Tomokazu Kawaoka; Daisuke Miyaki; Noriaki Naeshiro; Yuko Nagaoki; Takashi Nakahara; Hayato Sanetou; Shoichi Takahashi; Shintaro Takaki; Mio Tanaka; Koji Waki; Hiroshi Aikata; Koji Arihiro; Akira Hiramatsu; Youji Honda; Hideyuki Hyogo; Kazuaki Chayama
[A case of advanced hepatocellular carcinoma with lung, brain and lymph node metastases recurred 8 years after hepatectomy successfully treated by operation, radiation and systemic chemotherapy using S-1/CDDP].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2012;109(8):1401-8.
2012: Koichi Nakadoi; Shiro Oka; Shun-ichiro Ozawa; Sayaka Takata; Shinji Tanaka; Motomi Terasaki; Nana Hayashi; Hiroyuki Kanao; Kazuaki Chayama
Clinical outcomes of endoscopic submucosal dissection for rectal tumor close to the dentate line.
Gastrointestinal endoscopy 2012;76(2):444-50.
2012: Akihito Okazaki; Shoichi Takahashi; Chise Tateno; Masataka Tsuge; Katsutoshi Yoshizato; C Nelson Hayes; Nobuhiko Hiraga; Michio Imamura; Daiki Miki; Hidenori Ochi; Hideki Ohdan; Hiromi Abe; Hiroshi Aikata; Kazuaki Chayama
Severe necroinflammatory reaction caused by natural killer cell-mediated Fas/Fas ligand interaction and dendritic cells in human hepatocyte chimeric mouse.
Hepatology (Baltimore, Md.) 2012;56(2):555-66.
2012: Tatsuya Maruhashi; Takeshi Matsumoto; Shinsuke Mikami; Ayumu Nakashima; Kensuke Noma; Junko Soga; Bonpei Takase; Hirofumi Tomiyama; Akira Yamashina; Naomi Idei; Yumiko Iwamoto; Masato Kajikawa; Yasuki Kihara; Kazuaki Chayama; Noritaka Fujimura; Yukihito Higashi
Hyperbilirubinemia, augmentation of endothelial function, and decrease in oxidative stress in Gilbert syndrome.
Circulation 2012;126(5):598-603.
2012: C Nelson Hayes; Michio Imamura; Hiroshi Aikata; Kazuaki Chayama
Genetics of IL28B and HCV--response to infection and treatment.
Nature reviews. Gastroenterology & hepatology 2012;9(7):406-17.
2012: Mayu Ohnishi; Shoichi Takahashi; Shinji Tanaka; Masataka Tsuge; Yizhou Zhang; Hiromi Abe; Koji Arihiro; C Nelson Hayes; Nobuhiko Hiraga; Hideyuki Hyogo; Michio Imamura; Yuki Kimura; Tomohiko Kohno; Daiki Miki; Hidenori Ochi; Kazuaki Chayama
IL28B polymorphism is associated with fatty change in the liver of chronic hepatitis C patients.
Journal of gastroenterology 2012;47(7):834-44.
2012: Takayoshi Shishido; Shinji Tanaka; Ikue Watari; Shigeto Yoshida; Taiki Aoyama; Hiroki Imagawa; Shiro Oka; Kazuaki Chayama
Diagnostic yield of capsule endoscopy vs. double-balloon endoscopy for patients who have undergone total enteroscopy with obscure gastrointestinal bleeding.
Hepato-gastroenterology 2012;59(116):955-9.
2012: Hideyuki Hyogo; Tomokazu Ishitobi; Yuki Kimura; Sayaka Maeda; Sho-ichi Yamagishi; Kazuaki Chayama
Atorvastatin improves disease activity of nonalcoholic steatohepatitis partly through its tumour necrosis factor-α-lowering property.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2012;44(6):492-6.
2012: Koichi Nakadoi; Shiro Oka; Sayaka Takata; Shinji Tanaka; Motomi Terasaki; Shigeto Yoshida; Koji Arihiro; Hiroyuki Kanao; Kazuaki Chayama
Management of T1 colorectal carcinoma with special reference to criteria for curative endoscopic resection.
Journal of gastroenterology and hepatology 2012;27(6):1057-62.
2012: Akihiko Oshita; Shoichi Takahashi; Shintaro Takaki; Hirotaka Tashiro; Hironobu Amano; Koji Arihiro; Kazuaki Chayama; Kentaro Ide; Tsuyoshi Kobayashi; Takashi Onoe; Hideki Ohdan
Safety and feasibility of diet-treated donors with steatotic livers at the initial consultation for living-donor liver transplantation.
Transplantation 2012;93(10):1024-30.
2012: Masahiro Serikawa; Hirotaka Tashiro; Satoshi Yoshimi; Masanobu Yukutake; Koji Arihiro; Takashi Ishigaki; Yasutaka Ishii; Hiroshi Itsuki; Michihiro Kamigaki; Kenso Kobayashi; Keiichi Kosaka; Tomoyuki Minami; Teruo Mouri; Akihito Okazaki; Tamito Sasaki; Kazuaki Chayama
[Malignant phyllodes tumor metastatic to the pancreas: a case report].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2012;109(5):795-803.
2012: Shiro Oka; Sayaka Takata; Shinji Tanaka; Hiroyuki Kanao; Kazuaki Chayama
Usefulness and safety of SB knife Jr in endoscopic submucosal dissection for colorectal tumors.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2012;24 Suppl 1():90-5.
2012: Shinji Tanaka; Motomi Terasaki; Hiroyuki Kanao; Shiro Oka; Kazuaki Chayama
Current status and future perspectives of endoscopic submucosal dissection for colorectal tumors.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2012;24 Suppl 1():73-9.
2012: Tomohiro Iiboshi; Tamito Sasaki; Shuji Yonehara; Toshikatsu Fukuda; Keiji Hanada; Kazuaki Chayama
Value of cytodiagnosis using endoscopic nasopancreatic drainage for early diagnosis of pancreatic cancer: establishing a new method for the early detection of pancreatic carcinoma in situ.
Pancreas 2012;41(4):523-9.
2012: Mariko Kobayashi; Norio Akuta; Yasuji Arase; Kazuaki Chayama; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Yuzo Miyakawa; Satoshi Saitoh; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Association of two polymorphisms of the IL28B gene with viral factors and treatment response in 1,518 patients infected with hepatitis C virus.
Journal of gastroenterology 2012;47(5):596-605.
2012: Daiki Miki; Hidenori Ochi; Hiroshi Aikata; C Nelson Hayes; Kazuaki Chayama
Hepatocellular carcinoma: towards personalized medicine.
Cancer science 2012;103(5):846-50.
2012: Yuichiro Eguchi; Kazuma Fujimoto; Hideyuki Hyogo; Toshihiko Mizuta; Masafumi Ono; Naofumi Ono; Toshiji Saibara; Kazuaki Chayama
Prevalence and associated metabolic factors of nonalcoholic fatty liver disease in the general population from 2009 to 2010 in Japan: a multicenter large retrospective study.
Journal of gastroenterology 2012;47(5):586-95.
2012: Eisuke Murakami; Yuko Nagaoki; Yasushi Nagata; Shoichi Takahashi; Shintaro Takaki; Koji Waki; Hiroshi Aikata; Kazuo Awai; Akira Hiramatsu; Masaki Ishikawa; Hideaki Kakizawa; Yoshio Katamura; Tomokazu Kawaoka; Masahiro Kenjo; Tomoki Kimura; Daisuke Miyaki; Kazuaki Chayama
Hepatic arterial infusion chemotherapy using 5-fluorouracil and systemic interferon-α for advanced hepatocellular carcinoma in combination with or without three-dimensional conformal radiotherapy to venous tumor thrombosis in hepatic vein or inferior vena cava.
Hepatology research : the official journal of the Japan Society of Hepatology 2012;42(5):442-53.
2012: Masakazu Hashimoto; Tsuyoshi Kobayashi; Shintaro Kuroda; Hiroshi Aikata; Hironobu Amano; Koji Arihiro; Kazuaki Chayama; Masayoshi Fujii; Akihiko Oshita; Yoshisato Tanimoto; Hirotaka Tashiro; Hirofumi Tazawa; Hideki Ohdan
A huge metastatic liver tumor from leiomyosarcoma of the inferior vena cava: report of a case.
Surgery today 2012;42(5):505-8.
2012: Yuko Nagaoki; Takashi Nakahara; Shoichi Takahashi; Shintaro Takaki; Mio Tanaka; Koji Waki; Hiroshi Aikata; Akira Hiramatsu; Yoji Honda; Hideyuki Hyogo; Michio Imamura; Yoshiiku Kawakami; Tomokazu Kawaoka; Daisuke Miyaki; Noriaki Naeshiro; Kazuaki Chayama
Recent trend of clinical features in patients with hepatocellular carcinoma.
Hepatology research : the official journal of the Japan Society of Hepatology 2012;42(4):368-75.
2012: Motomi Terasaki; Shigeto Yoshida; Hiroyuki Kanao; Koichi Nakadoi; Shiro Oka; Sayaka Takata; Shinji Tanaka; Kazuaki Chayama
Clinical outcomes of endoscopic submucosal dissection and endoscopic mucosal resection for laterally spreading tumors larger than 20 mm.
Journal of gastroenterology and hepatology 2012;27(4):734-40.
2012: Keiichi Onji; Yoshito Takemura; Shinji Tanaka; Hiroyasu Yamada; Shigeto Yoshida; Masaharu Yoshihara; Shiro Oka; Masazumi Okajima; Kazuaki Chayama
Microvascular structure and perfusion imaging of colon cancer by means of contrast-enhanced ultrasonography.
Abdominal imaging 2012;37(2):297-303.
2012: Masaki Ishikawa; Hideaki Kakizawa; Yoshio Katamura; Naoyuki Toyota; Hiroshi Aikata; Kazuaki Chayama; Masashi Hieda; Kazuo Awai
Long-term outcomes of hepatic arterial port implantation using a coaxial microcatheter system in 176 patients with hepatocellular carcinoma.
Hiroshima journal of medical sciences 2012;61(1):7-13.
2012: Yoko Kominami; Motowo Mizuno; Yuki Morimoto; Masahiro Nakagawa; Asuka Nakarai; Norifumi Numata; Tsuneyoshi Ogawa; Hirotoki Ohe; Daisuke Uchida; Toru Ueki; Yasuyuki Araki; Reiji Higashi; Ken Hirao; Sayo Kobayashi; Kazuaki Chayama
[Classification of the bleeding pattern in colonic diverticulum is useful to predict the risk of bleeding or re-bleeding after endoscopic treatment].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2012;109(3):393-9.
2012: Waka Ohishi; Kazuaki Chayama
Treatment of chronic hepatitis B with nucleos(t)ide analogues.
Hepatology research : the official journal of the Japan Society of Hepatology 2012;42(3):219-25.
2012: Kazuaki Chayama; Eric Hughes; Kenji Ikeda; Hiroki Ishikawa; Yoshiyasu Karino; Fiona McPhee; Shoichi Takahashi; Joji Toyota; Hideaki Watanabe; Hiromitsu Kumada
Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders.
Hepatology (Baltimore, Md.) 2012;55(3):742-8.
2012: Masanori Ito; Taiji Matsuo; Shunsuke Takata; Shinji Tanaka; Yoshihiro Wada; Masaharu Yoshihara; Tomoyuki Boda; Kazuaki Chayama
Serum screening for detection of high-risk group for early-stage diffuse type gastric cancer in Japanese.
Journal of gastroenterology and hepatology 2012;27(3):598-602.
2012: Takayoshi Shishido; Yoshito Takemura; Shinji Tanaka; Shigeto Yoshida; Hiroki Imagawa; Shiro Oka; Kazuaki Chayama
Outcome of patients who have undergone total enteroscopy for obscure gastrointestinal bleeding.
World journal of gastroenterology : WJG 2012;18(7):666-72.
2012: Yoshitaka Ueno; Ryouhei Hayashi; Kenta Nagai; Shinji Tanaka; Kazuaki Chayama
[Differential diagnosis of ulcerative colitis and Crohn's disease].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 1():169-75.
2012: Bruno Sainz; Xuemei Yu; Waddah A Alrefai; Naina Barretto; Kazuaki Chayama; Nobuhiko Hiraga; Snawar Hussain; Michio Imamura; Katherine A Marsh; Danyelle N Martin; Susan L Uprichard
Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor.
Nature medicine 2012;18(2):281-5.
2012: Takayasu Kuwabara; Shiro Oka; Shinji Tanaka; Kazuaki Chayama; Toru Hiyama; Masaharu Yoshihara
Compliance with standard precautions among gastrointestinal endoscopists and endoscopy nurses in Japan.
American journal of infection control 2012;40(1):80.
2012: Yoshisato Tanimoto; Hirotaka Tashiro; Hirofumi Tazawa; Akihiko Oshita; Shoichi Takahashi; Hiroshi Aikata; Hironobu Amano; Kazuaki Chayama; Toshiyuki Itamoto; Tsuyoshi Kobayashi; Shintaro Kuroda; Hideki Ohdan
Impact of pegylated interferon therapy on outcomes of patients with hepatitis C virus-related hepatocellular carcinoma after curative hepatic resection.
Annals of surgical oncology 2012;19(2):418-25.
2012: C Nelson Hayes; Nobuhiko Hiraga; Michio Imamura; Yoshiiku Kawakami; Tomokazu Kawaoka; Daiki Miki; Hidenori Ochi; Waka Ohishi; Shoichi Takahashi; Masataka Tsuge; Hiromi Abe; Hiroshi Aikata; Sakura Akamatsu; Rie Akiyama; Kazuaki Chayama
Hepatitis B virus-specific miRNAs and Argonaute2 play a role in the viral life cycle.
PloS one 2012;7(10):e47490.
2012: Hideharu Okanobu; Seiji Onogawa; Shinji Tanaka; Morihisa Akagi; Songde Cho; Toru Hidaka; Masanori Ito; Shosuke Kitamura; Toshio Kuwai; Yoshiaki Matsumoto; Shinji Nagata; Hirotoki Oh-E; Shiro Okamoto; Kazuaki Chayama
Evaluation of individual risk in nonvariceal gastrointestinal bleeding patients with NSAID administration: a multicenter study in Japan.
Digestion 2012;86(3):187-93.
2012: Tomokazu Kawaoka; Daisuke Miyaki; Eisuke Murakami; Noriaki Naeshiro; Yuko Nagaoki; Takashi Nakahara; Shoichi Takahashi; Shintaro Takaki; Mio Tanaka; Koji Waki; Hiroshi Aikata; Akira Hiramatsu; Yoji Honda; Kazuaki Chayama
Evaluation of the mRECIST and α-fetoprotein ratio for stratification of the prognosis of advanced-hepatocellular-carcinoma patients treated with sorafenib.
Oncology 2012;83(4):192-200.
2012: Tomohiko Kohno; Daiki Miki; Hidenori Ochi; Mayu Ohnishi; Shoichi Takahashi; Shinji Tanaka; Masataka Tsuge; Tsuyoshi Hatakeyama; C Nelson Hayes; Nobuhiko Hiraga; Michio Imamura; Hiromi Abe; Kazuaki Chayama
Identification of novel HCV deletion mutants in chronic hepatitis C patients.
Antiviral therapy 2012;17(8):1551-61.
2012: Aya Kanbara; Yoshisuke Miura; Kazuaki Chayama; Hideyuki Hyogo; Issei Seyama
Effect of urine pH changed by dietary intervention on uric acid clearance mechanism of pH-dependent excretion of urinary uric acid.
Nutrition journal 2012;11():39.
2012: Yuji Urabe; Kazuaki Chayama; Naoyuki Kamatani; Kenjiro Kohri; Michiaki Kubo; Takashi Morizono; Yusuke Nakamura; Yukinori Okada; Atsushi Takahashi; Chizu Tanikawa; Tatsuhiko Tsunoda; Koichi Matsuda
A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35.3, 7p14.3, and 13q14.1.
PLoS genetics 2012;8(3):e1002541.
2012: Taiji Matsuo; Shunsuke Takata; Shinji Tanaka; Masana Tatsugami; Tomoyuki Boda; Masanori Ito; Kazuaki Chayama
Gastric cancer development after Helicobacter pylori eradication therapy: a new form of gastric neoplasia.
Digestion 2012;85(1):61-7.
2012: Yoshio Sumida; Yasuaki Suzuki; Masato Yoneda; Toshikazu Yoshikawa; Noriaki Aoki; Kazuaki Chayama; Yuichiro Eguchi; Hideki Fujii; Kazuma Fujimoto; Koji Fujita; Hideyuki Hyogo; Yoshito Itoh; Kazuyuki Kanemasa; Norifumi Kawada; Yutaka Kohgo; Takeshi Okanoue; Masafumi Ono; Toshiji Saibara
Validation of the FIB4 index in a Japanese nonalcoholic fatty liver disease population.
BMC gastroenterology 2012;12():2.
2012: Tomokazu Kawaoka; Daiki Miki; Yuko Nagaoki; Hidenori Ochi; Hideki Ohdan; Shoichi Takahashi; Shintaro Takaki; Hirotaka Tashiro; Masataka Tsuge; Koji Waki; Yoshimasa Hashimoto; Nobuhiko Hiraga; Akira Hiramatsu; Michio Imamura; Yoshio Katamura; Yoshiiku Kawakami; Hiroshi Aikata; Kazuaki Chayama
Achievement of sustained viral response after switching treatment from pegylated interferon α-2b to α-2a and ribavirin in patients with recurrence of hepatitis C virus genotype 1 infection after liver transplantation: a case report.
Intervirology 2012;55(4):306-10.
2012: Yoji Sanomura; Takayoshi Shishido; Shinji Tanaka; Shigeto Yoshida; Makoto Higashiyama; Toru Hiyama; Hiroki Imagawa; Ikue Noda; Shiro Oka; Koji Arihiro; Kazuaki Chayama
Clinical validity of endoscopic submucosal dissection for submucosal invasive gastric cancer: a single-center study.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2012;15(1):97-105.
2012: Norio Akuta; Yasuji Arase; Kazuaki Chayama; Miharu Hirakawa; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Yusuke Nakamura; Satoshi Saitoh; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromitsu Kumada
Amino acid substitution in HCV core/NS5A region and genetic variation near IL28B gene affect treatment efficacy to interferon plus ribavirin combination therapy.
Intervirology 2012;55(3):231-41.
2012: Norio Akuta; Yasuji Arase; Kazuaki Chayama; Miharu Hirakawa; Tetsuya Hosaka; Kenji Ikeda; Yusuke Kawamura; Masahiro Kobayashi; Mariko Kobayashi; Yusuke Nakamura; Satoshi Saitoh; Hitomi Sezaki; Fumitaka Suzuki; Yoshiyuki Suzuki; Hiromi Yatsuji; Hiromitsu Kumada
Amino acid substitution in HCV core region and genetic variation near the IL28B gene affect viral dynamics during telaprevir, peginterferon and ribavirin treatment.
Intervirology 2012;55(6):417-25.
2011: Noriaki Naeshiro; Koji Waki; Hiroshi Aikata; Kazuaki Chayama
[Q & A. Intra-hepatic multiple nodules developing following treatment of hepatic calculi].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2011;108(12):2056-7, 2060-1.
2011: Fukiko Mitsui; Yuko Nagaoki; Shoichi Takahashi; Shintaro Takaki; Masataka Tsuge; Koji Waki; Hiroshi Aikata; Koji Arihiro; Yoshimasa Hashimoto; Nobuhiko Hiraga; Akira Hiramatsu; Michio Imamura; Yoshio Katamura; Yoshiiku Kawakami; Tomokazu Kawaoka; Yuki Kimura; Kazuaki Chayama
A first case of hepatic angiosarcoma treated with recombinant interleukin-2.
Hiroshima journal of medical sciences 2011;60(4):91-6.
2011: Taiji Matsuo; Shunsuke Takata; Shinji Tanaka; Masaharu Yoshihara; Masanori Ito; Kazuaki Chayama
Low prevalence of Helicobacter pylori-negative gastric cancer among Japanese.
Helicobacter 2011;16(6):415-9.
2011: Yuichi Fujii; Noritaka Fujimura; Kazuaki Chayama; Yasuki Kihara; Tatsuya Maruhashi; Shinsuke Mikami; Kensuke Noma; Yukihito Higashi
Flow-mediated vasodilation is augmented in a corkscrew collateral artery compared with that in a native artery in patients with thromboangiitis obliterans (Buerger disease).
Journal of vascular surgery 2011;54(6):1689-97.
2011: Tomokazu Kawaoka; Daiki Miki; Daisuke Miyaki; Eisuke Murakami; Yuko Nagaoki; Hidenori Ochi; Hideki Ohdan; Shoichi Takahashi; Shintaro Takaki; Hirotaka Tashiro; Masataka Tsuge; Koji Waki; Yoshimasa Hashimoto; Nobuhiko Hiraga; Akira Hiramatsu; Michio Imamura; Yoshio Katamura; Yoshiiku Kawakami; Hiroshi Aikata; Takahiro Azakami; Kazuaki Chayama
Eradication of hepatitis C virus genotype 1 after liver transplantation by interferon therapy before surgery: Report of three patients with analysis of interleukin-28 polymorphism, hepatitis C virus core region and interferon-sensitivity determining region.
Hepatology research : the official journal of the Japan Society of Hepatology 2011;41(11):1126-31.
2011: Hideaki Kodama; Daisuke Miyaki; Eisuke Murakami; Yuko Nagaoki; Yasushi Nagata; Shoichi Takahashi; Shintaro Takaki; Koji Waki; Yoshimasa Hashimoto; Akira Hiramatsu; Michio Imamura; Masaki Ishikawa; Hideaki Kakizawa; Yoshio Katamura; Yoshiiku Kawakami; Tomokazu Kawaoka; Masahiro Kenjo; Hiroshi Aikata; Kazuo Awai; Takahiro Azakami; Kazuaki Chayama
Clinical outcome of esophageal varices after hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with major portal vein tumor thrombus.
Hepatology research : the official journal of the Japan Society of Hepatology 2011;41(11):1046-56.
2011: R Hanaoka; K Nagai; T Onitake; Shinji Tanaka; Yoshitaka Ueno; K Yoshioka; Kazuaki Chayama
The water-soluble extract from cultured medium of Ganoderma lucidum (Reishi) mycelia (Designated as MAK) ameliorates murine colitis induced by trinitrobenzene sulphonic acid.
Scandinavian journal of immunology 2011;74(5):454-62.
2011: Kenso Kobayashi; Tamito Sasaki; Masahiro Serikawa; Motoki Inoue; Hiroshi Itsuki; Kazuaki Chayama
Assessment of trypsinogen-2 levels as an early diagnostic for post-endoscopic retrograde cholangiopancreatography pancreatitis.
Pancreas 2011;40(8):1206-10.
2011: Masato Yoneda; Toshikazu Yoshikawa; Noriaki Aoki; Kazuaki Chayama; Yuichiro Eguchi; Hideki Fujii; Kazuma Fujimoto; Hideyuki Hyogo; Kento Imajo; Yoshito Itoh; Kazuyuki Kanemasa; Norifumi Kawada; Yutaka Kohgo; Takeshi Okanoue; Masafumi Ono; Toshiji Saibara; Yoshio Sumida; Yasuaki Suzuki
Platelet count for predicting fibrosis in nonalcoholic fatty liver disease.
Journal of gastroenterology 2011;46(11):1300-6.
2011: Makoto Higashiyama; Hiroki Imagawa; Shiro Oka; Yoji Sanomura; Takayoshi Shishido; Shinji Tanaka; Shigeto Yoshida; Kazuaki Chayama
Risk factors for bleeding after endoscopic submucosal dissection of gastric epithelial neoplasm.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2011;23(4):290-5.
2011: Hamdi Mbarek; Daiki Miki; Yusuke Nakamura; Hidenori Ochi; Atsushi Takahashi; Tatsuhiko Tsunoda; Yuji Urabe; Hiromi Abe; Kazuaki Chayama; Naoya Hosono; Naoyuki Kamatani; Yoichiro Kamatani; Michiaki Kubo; Vinod Kumar; Koichi Matsuda
A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
Human molecular genetics 2011;20(19):3884-92.
2011: Junko Soga; Kazuaki Chayama; Yuichi Fujii; Noritaka Fujimura; Takaki Hata; Takayuki Hidaka; Yukihito Higashi; Naomi Idei; Hitoshi Kato; Yasuki Kihara; James K Liao; Tatsuya Maruhashi; Shinsuke Mikami; Kensuke Noma
Rho-associated kinase activity, endothelial function, and cardiovascular risk factors.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(10):2353-9.
2011: Kengo Yoshida; Masazumi Akahoshi; Kazuaki Chayama; Saeko Fujiwara; Masayuki Hakoda; Tomonori Hayashi; Fumiyoshi Kasagi; Seishi Kyoizumi; Kei Nakachi; Eiji Nakashima; Waka Ohishi; Yoichiro Kusunoki
Lymphocyte subset characterization associated with persistent hepatitis C virus infection and subsequent progression of liver fibrosis.
Human immunology 2011;72(10):821-6.
2011: Takako Shimomura; Shinji Tanaka; Masaharu Yoshihara; Toru Hiyama; Shiro Oka; Fumio Shimamoto; Kazuaki Chayama
Frequent somatic mutations of mitochondrial DNA in traditional serrated adenomas but not in sessile serrated adenomas of the colorectum.
Journal of gastroenterology and hepatology 2011;26(10):1565-9.
2011: Waka Ohishi; Kazuaki Chayama
Prevention of hepatitis B virus reactivation in immunosuppressive therapy or chemotherapy.
Clinical and experimental nephrology 2011;15(5):634-40.
2011: Kenta Nagai; Toshiko Onitake; Shinji Tanaka; Yoshitaka Ueno; Yoshihiro Wada; Rie Hanaoka; Ryohei Hayashi; Kazuaki Chayama
Intestinal Tuberculosis with Hoarseness as a Chief Complaint due to Mediastinal Lymphadenitis.
Case reports in gastroenterology 2011;5(3):540-5.
2011: Hiromi Abe; C Nelson Hayes; Nobuhiko Hiraga; Michio Imamura; Naoyuki Kamatani; Michiaki Kubo; Daiki Miki; Yusuke Nakamura; Hidenori Ochi; Shoichi Takahashi; Masataka Tsuge; Kazuaki Chayama
Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state.
Journal of medical virology 2011;83(9):1597-607.
2011: Akemi Takamura; Shunsuke Takata; Shinji Tanaka; Claudio R Teixeira; Ken Haruma; Shinobu Imagawa; Masanori Ito; Tomoari Kamada; Kazuaki Chayama
Helicobacter pylori cagA polymorphism and gastric inflammation: an international comparison between Japanese and Brazilian patients.
Scandinavian journal of gastroenterology 2011;46(9):1051-6.
2011: Michihiro Kamigaki; Kenso Kobayashi; Keiichi Kosaka; Tomoyuki Minami; Akihito Okazaki; Tamito Sasaki; Masahiro Serikawa; Masanobu Yukutake; Motoki Inoue; Takashi Ishigaki; Yasutaka Ishii; Hiroshi Itsuki; Kazuaki Chayama
Statins induce apoptosis and inhibit proliferation in cholangiocarcinoma cells.
International journal of oncology 2011;39(3):561-8.
2011: Hiroki Imagawa; Ikue Noda; Shiro Oka; Youji Sanomura; Takayoshi Shishido; Shinji Tanaka; Shigeto Yoshida; Makoto Higashiyama; Kazuaki Chayama
Improved detectability of small-bowel lesions via capsule endoscopy with computed virtual chromoendoscopy: a pilot study.
Scandinavian journal of gastroenterology 2011;46(9):1133-7.
2011: Daiki Miki; Takashi Morizono; Yusuke Nakamura; Hidenori Ochi; Joji Toyota; Tatsuhiko Tsunoda; Tadahiko Yoshima; C Nelson Hayes; Kenji Ikeda; Naoyuki Kamatani; Michiaki Kubo; Hiromitsu Kumada; Hiromi Abe; Hiroshi Aikata; Kazuaki Chayama
Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers.
Nature genetics 2011;43(8):797-800.
2011: Mohsan Saeed; Masaaki Shiina; Tetsuro Suzuki; Takaji Wakita; Haruo Watanabe; Noriyuki Watanabe; Daisuke Akazawa; Kazuaki Chayama; Youkyung Choi; Tomoko Date; Nobuhiko Hiraga; Michio Imamura; Krzysztof Krawczynski; T Jake Liang; Asako Murayama; Takanobu Kato
In vivo adaptation of hepatitis C virus in chimpanzees for efficient virus production and evasion of apoptosis.
Hepatology (Baltimore, Md.) 2011;54(2):425-33.
2011: Masataka Tsuge; Yizhou Zhang; Hiromi Abe; Yoshifumi Fujimoto; C Nelson Hayes; Nobuhiko Hiraga; Michio Imamura; Tomokazu Kawaoka; Fukiko Mitsui; Hidenori Ochi; Shoichi Takahashi; Kazuaki Chayama
Effects of hepatitis B virus infection on the interferon response in immunodeficient human hepatocyte chimeric mice.
The Journal of infectious diseases 2011;204(2):224-8.
2011: Hiroshi Kohno; Hirotaka Kouno; Shiomi Aimitsu; Yasuyuki Aisaka; Hiroiku Kawakami; Mikiya Kitamoto; Kazuaki Chayama
Impact of ribavirin dose reduction on the efficacy of pegylated interferon plus ribavirin combination therapy for elderly patients infected with genotype 1b and high viral loads.
Hepatology research : the official journal of the Japan Society of Hepatology 2011;41(7):626-34.
2011: Hirotaka Tashiro; Hirofumi Tazawa; Koji Waki; Akihiko Oshita; Yoshisato Tanimoto; Hiroshi Aikata; Hironobu Amano; Toshimasa Asahara; Kazuaki Chayama; Tsuyoshi Kobayashi; Shintaro Kuroda; Hideki Ohdan
Treatment strategy for early hepatocellular carcinomas: comparison of radiofrequency ablation with or without transcatheter arterial chemoembolization and surgical resection.
Journal of surgical oncology 2011;104(1):3-9.
2011: Kazuaki Chayama; C Nelson Hayes; Hiromi Abe; Daiki Miki; Hidenori Ochi; Yoshiyasu Karino; Joji Toyota; Yusuke Nakamura; Naoyuki Kamatani; Hitomi Sezaki; Mariko Kobayashi; Norio Akuta; Fumitaka Suzuki; Hiromitsu Kumada
IL28B but not ITPA polymorphism is predictive of response to pegylated interferon, ribavirin, and telaprevir triple therapy in patients with genotype 1 hepatitis C.
The Journal of infectious diseases 2011;204(1):84-93.
2011: Takaji Wakita; Kazuaki Chayama; Nobuyuki Enomoto; Matthew J Evans; Makoto Hijikata; Tatsuya Kanto; Nobuyuki Kato; Kazuhiko Koike; Yoshiharu Matsuura; Kohji Moriishi; Tsukasa Seya; Kunitada Shimotohno; Tetsuro Suzuki; Hak Hotta
Will there be an HCV meeting in 2020? Summary of the 17th international meeting on hepatitis C virus and related viruses.
Gastroenterology 2011;141(1):e1-5.
2011: Itaru Ozeki; Takahiro Sato; Ichimaro Yamada; Jun Akaike; Tomohiro Arakawa; Kazuaki Chayama; Naohiro Kamiya; Yoshiyasu Karino; Hiromitsu Kumada; Yasuaki Kuwata; Takumi Ohmura; Jouji Toyota
Antiviral effects of peginterferon alpha-2b and ribavirin following 24-week monotherapy of telaprevir in Japanese hepatitis C patients.
Journal of gastroenterology 2011;46(7):929-37.
2011: Hiromi Abe; Kenji Asai; C Nelson Hayes; Nobuhiko Hiraga; Michio Imamura; Tomokazu Kawaoka; Toshiro Maekawa; Takashi Matsuhira; Fukiko Mitsui; Shoichi Murakami; Hidenori Ochi; Shoichi Takahashi; Chise Tateno; Masataka Tsuge; Nobuyuki Yamashita; Katsutoshi Yoshizato; Kazuaki Chayama
ME3738 enhances the effect of interferon and inhibits hepatitis C virus replication both in vitro and in vivo.
Journal of hepatology 2011;55(1):11-8.
2011: Kenji Kajiwara; Hideaki Kakizawa; Takayuki Suzuki; Naoko Takeuchi; Chihiro Tani; Keizo Tanitame; Naoyuki Toyota; Kazuaki Chayama; Koichi Fujikawa; Masashi Hieda; Masaki Ishikawa; Hiroshi Aikata; Kazuo Awai
Cutaneous complications after transcatheter arterial treatment for hepatocellular carcinoma via the internal mammary artery: how to avoid this complication.
Japanese journal of radiology 2011;29(5):307-15.
2011: Daisuke Miyaki; Eisuke Murakami; Yuko Nagaoki; Toshihide Ohya; Hideto Sakimoto; Shoichi Takahashi; Shintaro Takaki; Koji Waki; Yoshimasa Hashimoto; Akira Hiramatsu; Michio Imamura; Yoshio Katamura; Tomokazu Kawaoka; Hiroshi Aikata; Koji Arihiro; Kazuaki Chayama
[Significant regression of a cavernous hepatic hemangioma to a sclerosed hemangioma over 12 years: a case study].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2011;108(6):954-61.
2011: Takahiro Azakami; C Nelson Hayes; Hitomi Sezaki; Mariko Kobayashi; Norio Akuta; Fumitaka Suzuki; Hiromitsu Kumada; Hiromi Abe; Daiki Miki; Masataka Tsuge; Michio Imamura; Yoshiiku Kawakami; Shoichi Takahashi; Hidenori Ochi; Yusuke Nakamura; Naoyuki Kamatani; Kazuaki Chayama
Common genetic polymorphism of ITPA gene affects ribavirin-induced anemia and effect of peg-interferon plus ribavirin therapy.
Journal of medical virology 2011;83(6):1048-57.
2011: Yoshimasa Hashimoto; Hidenori Ochi; Hiromi Abe; Yasufumi Hayashida; Masataka Tsuge; Fukiko Mitsui; Nobuhiko Hiraga; Michio Imamura; Shoichi Takahashi; C Nelson Hayes; Waka Ohishi; Michaki Kubo; Tatsuhiko Tsunoda; Naoyuki Kamatani; Yusuke Nakamura; Kazuaki Chayama
Prediction of response to peginterferon-alfa-2b plus ribavirin therapy in Japanese patients infected with hepatitis C virus genotype 1b.
Journal of medical virology 2011;83(6):981-8.
2011: Yuko Nagaoki; Shoichi Takahashi; Shintaro Takaki; Koji Waki; Hiroshi Aikata; Takahiro Azakami; Yoshimasa Hashimoto; Akira Hiramatsu; Michio Imamura; Yoshio Katamura; Yoshiiku Kawakami; Tomokazu Kawaoka; Daisuke Miyaki; Eisuke Murakami; Kazuaki Chayama
Clinical features and prognosis in patients with hepatocellular carcinoma that developed after hepatitis C virus eradication with interferon therapy.
Journal of gastroenterology 2011;46(6):799-808.
2011: Hiromi Abe; C Nelson Hayes; Hidenori Ochi; Toshiro Maekawa; Masataka Tsuge; Daiki Miki; Fukiko Mitsui; Nobuhiko Hiraga; Michio Imamura; Shoichi Takahashi; Michiaki Kubo; Yusuke Nakamura; Kazuaki Chayama
IL28 variation affects expression of interferon stimulated genes and peg-interferon and ribavirin therapy.
Journal of hepatology 2011;54(6):1094-101.
2011: Michio Imamura; Nobuhiko Hiraga; Kazuaki Chayama
[HCV replication animal model].
Nihon rinsho. Japanese journal of clinical medicine 2011;69 Suppl 4():75-9.
2011: Shiro Oka; Shinji Tanaka; Sayaka Takata; Hiroyuki Kanao; Kazuaki Chayama
Clinical usefulness of narrow band imaging magnifying classification for colorectal tumors based on both surface pattern and microvessel features.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2011;23 Suppl 1():101-5.
2011: Tomonori Sumida; Yasuhiko Kitadai; Kei Shinagawa; Miwako Tanaka; Michiyo Kodama; Mayu Ohnishi; Eiji Ohara; Shinji Tanaka; Wataru Yasui; Kazuaki Chayama
Anti-stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model.
International journal of cancer. Journal international du cancer 2011;128(9):2050-62.
2011: Hidenori Ochi; Toshiro Maekawa; Hiromi Abe; Yasufumi Hayashida; Rikita Nakano; Michio Imamura; Nobuhiko Hiraga; Yoshiiku Kawakami; Shiomi Aimitsu; Jia-Horng Kao; Michiaki Kubo; Tatsuhiko Tsunoda; Hiromitsu Kumada; Yusuke Nakamura; C Nelson Hayes; Kazuaki Chayama
IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations.
The Journal of general virology 2011;92(Pt 5):1071-81.
2011: Eiji Ohara; Nobuhiko Hiraga; Michio Imamura; Eiji Iwao; Naohiro Kamiya; Ichimaro Yamada; Tomohiko Kono; Mayu Onishi; Daizaburo Hirata; Fukiko Mitsui; Tomokazu Kawaoka; Masataka Tsuge; Shoichi Takahashi; Hiromi Abe; C Nelson Hayes; Hidenori Ochi; Chise Tateno; Katsutoshi Yoshizato; Shinji Tanaka; Kazuaki Chayama
Elimination of hepatitis C virus by short term NS3-4A and NS5B inhibitor combination therapy in human hepatocyte chimeric mice.
Journal of hepatology 2011;54(5):872-8.
2011: Waka Ohishi; Saeko Fujiwara; John B Cologne; Gen Suzuki; Masazumi Akahoshi; Nobuo Nishi; Masataka Tsuge; Kazuaki Chayama
Impact of radiation and hepatitis virus infection on risk of hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 2011;53(4):1237-45.
2011: Kazuaki Chayama; C Nelson Hayes; Kentaro Yoshioka; Hisataka Moriwaki; Takashi Okanoue; Shotaro Sakisaka; Tetsuo Takehara; Makoto Oketani; Joji Toyota; Namiki Izumi; Yoichi Hiasa; Akihiro Matsumoto; Hideyuki Nomura; Masataka Seike; Yoshiyuki Ueno; Hiroshi Yotsuyanagi; Hiromitsu Kumada
Factors predictive of sustained virological response following 72 weeks of combination therapy for genotype 1b hepatitis C.
Journal of gastroenterology 2011;46(4):545-55.
2011: Yoshifumi Fujimoto; Hidenori Ochi; Toshiro Maekawa; Hiromi Abe; C Nelson Hayes; Hiromitsu Kumada; Yusuke Nakamura; Kazuaki Chayama
A single nucleotide polymorphism in activated Cdc42 associated tyrosine kinase 1 influences the interferon therapy in hepatitis C patients.
Journal of hepatology 2011;54(4):629-39.
2011: Takayasu Kuwabara; Yuji Urabe; Toru Hiyama; Shinji Tanaka; Takako Shimomura; Shiro Oko; Masaharu Yoshihara; Kazuaki Chayama
Prevalence and impact of musculoskeletal pain in Japanese gastrointestinal endoscopists: a controlled study.
World journal of gastroenterology : WJG 2011;17(11):1488-93.
2011: Hideaki Kakizawa; Akihito Okazaki; Shintaro Takaki; Chihiro Tani; Keizo Tanitame; Naoyuki Toyota; Hiroshi Aikata; Kazuaki Chayama; Masashi Hieda; Masaki Ishikawa; Kazuo Awai
Portal-systemic shunt between the inferior mesenteric vein and inferior vena cava in a patient with hepatic encephalopathy: successful occlusion by balloon-occluded retrograde transvenous obliteration.
Hiroshima journal of medical sciences 2011;60(1):15-9.
2011: Masana Tatsugami; Yoshihiro Wada; Masaharu Yoshihara; Ken Haruma; Shinobu Imagawa; Kazuhiko Ishihara; Masanori Ito; Shosuke Kitamura; Yoshiaki Matsumoto; Atsunori Sasaki; Masaharu Sumii; Akemi Takamura; Shunsuke Takata; Shinji Tanaka; Kazuaki Chayama
Plaunotol induces a comparative increase of acidic mucin fraction in gastric juice.
Hepato-gastroenterology 2011;58(106):663-8.
2011: Motoki Inoue; Susumu Tazuma; Keishi Kanno; Hideyuki Hyogo; Kazuhiko Igarashi; Kazuaki Chayama
Bach1 gene ablation reduces steatohepatitis in mouse MCD diet model.
Journal of clinical biochemistry and nutrition 2011;48(2):161-6.
2011: Marlen Doskali; Yuka Tanaka; Masahiro Ohira; Kohei Ishiyama; Hirotaka Tashiro; Kazuaki Chayama; Hideki Ohdan
Possibility of adoptive immunotherapy with peripheral blood-derived CD3⁻CD56+ and CD3+CD56+ cells for inducing antihepatocellular carcinoma and antihepatitis C virus activity.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2011;34(2):129-38.
2011: Tomokazu Kawaoka; C Nelson Hayes; Waka Ohishi; Hidenori Ochi; Toshiro Maekawa; Hiromi Abe; Masataka Tsuge; Fukiko Mitsui; Nobuhiko Hiraga; Michio Imamura; Shoichi Takahashi; Michaki Kubo; Tatsuhiko Tsunoda; Yusuke Nakamura; Hiromitsu Kumada; Kazuaki Chayama
Predictive value of the IL28B polymorphism on the effect of interferon therapy in chronic hepatitis C patients with genotypes 2a and 2b.
Journal of hepatology 2011;54(3):408-14.
2011: Yuki Kimura; Hideyuki Hyogo; Tomokazu Ishitobi; Yoshitaka Nabeshima; Koji Arihiro; Kazuaki Chayama
Postprandial insulin secretion pattern is associated with histological severity in non-alcoholic fatty liver disease patients without prior known diabetes mellitus.
Journal of gastroenterology and hepatology 2011;26(3):517-22.
2011: Hiroki Imagawa; Shiro Oka; Shinji Tanaka; Ikue Noda; Makoto Higashiyama; Youji Sanomura; Takayoshi Shishido; Shigeto Yoshida; Kazuaki Chayama
Improved visibility of lesions of the small intestine via capsule endoscopy with computed virtual chromoendoscopy.
Gastrointestinal endoscopy 2011;73(2):299-306.
2011: Yuji Urabe; Toru Hiyama; Shinji Tanaka; Masaharu Yoshihara; Koji Arihiro; Kazuaki Chayama
Advantages of endoscopic submucosal dissection versus endoscopic oblique aspiration mucosectomy for superficial esophageal tumors.
Journal of gastroenterology and hepatology 2011;26(2):275-80.
2011: Fumitaka Suzuki; Yoshiyuki Suzuki; Norio Akuta; Hitomi Sezaki; Miharu Hirakawa; Yusuke Kawamura; Tetsuya Hosaka; Masahiro Kobayashi; Satoshi Saito; Yasuji Arase; Kenji Ikeda; Mariko Kobayashi; Kazuaki Chayama; Naoyuki Kamatani; Yusuke Nakamura; Yuzo Miyakawa; Hiromitsu Kumada
Influence of ITPA polymorphisms on decreases of hemoglobin during treatment with pegylated interferon, ribavirin, and telaprevir.
Hepatology (Baltimore, Md.) 2011;53(2):415-21.
2011: Naomi Idei; Junko Soga; Takaki Hata; Yuichi Fujii; Noritaka Fujimura; Shinsuke Mikami; Tatsuya Maruhashi; Kenji Nishioka; Takayuki Hidaka; Yasuki Kihara; Moniruddin Chowdhury; Kensuke Noma; Akira Taguchi; Kazuaki Chayama; Taijiro Sueda; Yukihito Higashi
Autologous bone-marrow mononuclear cell implantation reduces long-term major amputation risk in patients with critical limb ischemia: a comparison of atherosclerotic peripheral arterial disease and Buerger disease.
Circulation. Cardiovascular interventions 2011;4(1):15-25.
2011: Takayasu Kuwabara; Toru Hiyama; Shinji Tanaka; Masaharu Yoshihara; Koji Arihiro; Kazuaki Chayama
Genetic pathways of multiple esophageal squamous cell carcinomas.
Oncology reports 2011;25(2):453-9.
2011: C Nelson Hayes; Mariko Kobayashi; Norio Akuta; Fumitaka Suzuki; Hiromitsu Kumada; Hiromi Abe; Daiki Miki; Michio Imamura; Hidenori Ochi; Naoyuki Kamatani; Yusuke Nakamura; Kazuaki Chayama
HCV substitutions and IL28B polymorphisms on outcome of peg-interferon plus ribavirin combination therapy.
Gut 2011;60(2):261-7.
2011: Takaki Hata; Junko Soga; Takayuki Hidaka; Naomi Idei; Yuichi Fujii; Noritaka Fujimura; Shinsuke Mikami; Tatsuya Maruhashi; Yasuki Kihara; Kazuaki Chayama; Hitoshi Kato; Kensuke Noma; James K Liao; Yukihito Higashi
Calcium channel blocker and Rho-associated kinase activity in patients with hypertension.
Journal of hypertension 2011;29(2):373-9.
2011: Yoshio Sumida; Masato Yoneda; Hideyuki Hyogo; Kanji Yamaguchi; Masafumi Ono; Hideki Fujii; Yuichiro Eguchi; Yasuaki Suzuki; Shunsuke Imai; Kazuyuki Kanemasa; Koji Fujita; Kazuaki Chayama; Kohichiroh Yasui; Toshiji Saibara; Norifumi Kawada; Kazuma Fujimoto; Yutaka Kohgo; Takeshi Okanoue
A simple clinical scoring system using ferritin, fasting insulin, and type IV collagen 7S for predicting steatohepatitis in nonalcoholic fatty liver disease.
Journal of gastroenterology 2011;46(2):257-68.
2011: Masataka Tsuge; Tatsuhiko Tsunoda; Yizhou Zhang; Hiromi Abe; Yoshifumi Fujimoto; C Nelson Hayes; Nobuhiko Hiraga; Michio Imamura; Tomohiko Kohno; Daiki Miki; Fuyuki Miya; Hidenori Ochi; Mayu Ohnishi; Shoichi Takahashi; Kazuaki Chayama
Hepatitis C virus infection suppresses the interferon response in the liver of the human hepatocyte chimeric mouse.
PloS one 2011;6(8):e23856.
2011: Yuichiro Ushitora; Hirotaka Tashiro; Shoichi Takahashi; Hironobu Amano; Akihiko Oshita; Tsuyoshi Kobayashi; Kazuaki Chayama; Hideki Ohdan
Splenectomy in chronic hepatic disorders: portal vein thrombosis and improvement of liver function.
Digestive surgery 2011;28(1):9-14.
2011: S Oba; Shinji Tanaka; yasushi sano; Shiro Oka; Kazuaki Chayama
Current status of narrow-band imaging magnifying colonoscopy for colorectal neoplasia in Japan.
Digestion 2011;83(3):167-72.
2011: Kazuaki Chayama; C Nelson Hayes
Hepatitis C virus: How genetic variability affects pathobiology of disease.
Journal of gastroenterology and hepatology 2011;26 Suppl 1():83-95.
2011: Kazuaki Chayama; C Nelson Hayes; Nobuhiko Hiraga; Hiromi Abe; Masataka Tsuge; Michio Imamura
Animal model for study of human hepatitis viruses.
Journal of gastroenterology and hepatology 2011;26(1):13-8.
2011: Naomi Idei; Kenji Nishioka; Junko Soga; Takayuki Hidaka; Takaki Hata; Yuichi Fujii; Noritaka Fujimura; Tatsuya Maruhashi; Shinsuke Mikami; Hiroki Teragawa; Yasuki Kihara; Kensuke Noma; Kazuaki Chayama; Yukihito Higashi
Vascular function and circulating progenitor cells in thromboangitis obliterans (Buerger's disease) and atherosclerosis obliterans.
Hypertension 2011;57(1):70-8.
2011: Osamu Yokosuka; Yasuji Arase; Kazuaki Chayama; Fumio Imazeki; Namiki Izumi; Hiromitsu Kumada; Masayuki Kurosaki; Masashi Mizokami; Eiji Tanaka; Yasuhito Tanaka; Masatoshi Kudo
Management of hepatitis B: Consensus of the Japan Society of Hepatology 2009.
Hepatology research : the official journal of the Japan Society of Hepatology 2011;41(1):1-21.
2011: Takaki Hata; Chikara Goto; Junko Soga; Takayuki Hidaka; Yuichi Fujii; Naomi Idei; Noritaka Fujimura; Tatsuya Maruhashi; Shinsuke Mikami; Yasuki Kihara; Kazuaki Chayama; Kensuke Noma; James K Liao; Yukihito Higashi
Measurement of Rho-associated kinase (ROCK) activity in humans: validity of leukocyte p-MBS/t-MBS in comparison with vascular response to fasudil.
Atherosclerosis 2011;214(1):117-21.
2010: Yoshio Katamura; Hiroshi Aikata; Yoshimasa Hashimoto; Yuki Kimura; Tomokazu Kawaoka; Shintaro Takaki; Koji Waki; Akira Hiramatsu; Yoshiiku Kawakami; Shoichi Takahashi; Masahiro Kenjo; Kazuaki Chayama
Zoledronic acid delays disease progression of bone metastases from hepatocellular carcinoma.
Hepatology research : the official journal of the Japan Society of Hepatology 2010;40(12):1195-203.
2010: Kazuaki Chayama; C Nelson Hayes; Yoichi Hiasa; Namiki Izumi; Akihiro Matsumoto; Hisataka Moriwaki; Hideyuki Nomura; Takeshi Okanoue; Makoto Oketani; Shotaro Sakisaka; Masataka Seike; Tetsuo Takehara; Joji Toyota; Yoshiyuki Ueno; Kentaro Yoshioka; Hiroshi Yotsuyanagi; Hiromitsu Kumada
Accumulation of refractory factors for pegylated interferon plus ribavirin therapy in older female patients with chronic hepatitis C.
Hepatology research : the official journal of the Japan Society of Hepatology 2010;40(12):1155-67.
2010: Shinobu Imagawa; Masanori Ito; Masaharu Yoshihara; Hidetaka Eguchi; Shinji Tanaka; Kazuaki Chayama
Helicobacter pylori dupA and gastric acid secretion are negatively associated with gastric cancer development.
Journal of medical microbiology 2010;59(Pt 12):1484-9.
2010: Tomokazu Kawaoka; Nobuhiko Hiraga; Shoichi Takahashi; Shintaro Takaki; Fukiko Mitsui; Masataka Tsuge; Yuko Nagaoki; Yuki Kimura; Yoshimasa Hashimoto; Yoshio Katamura; Akira Hiramatsu; Koji Waki; Michio Imamura; Yoshiiku Kawakami; Hiroshi Aikata; Hirotaka Tashiro; Hideki Ohdan; Kazuaki Chayama
Prolongation of interferon therapy for recurrent hepatitis C after living donor liver transplantation: analysis of predictive factors of sustained virological response, including amino acid sequence of the core and NS5A regions of hepatitis C virus.
Scandinavian journal of gastroenterology 2010;45(12):1488-96.
2010: Yoji Sanomura; Shiro Oka; Shinji Tanaka; Makoto Higashiyama; Shigeto Yoshida; Koji Arihiro; Fumio Shimamoto; Kazuaki Chayama
Predicting the absence of lymph node metastasis of submucosal invasive gastric cancer: expansion of the criteria for curative endoscopic resection.
Scandinavian journal of gastroenterology 2010;45(12):1480-7.
2010: Kei Shinagawa; Yasuhiko Kitadai; Miwako Tanaka; Tomonori Sumida; Michiyo Kodama; Yukihito Higashi; Shinji Tanaka; Wataru Yasui; Kazuaki Chayama
Mesenchymal stem cells enhance growth and metastasis of colon cancer.
International journal of cancer. Journal international du cancer 2010;127(10):2323-33.
2010: Goki Suda; Naoya Sakamoto; Yasuhiro Itsui; Mina Nakagawa; Megumi Tasaka-Fujita; Yusuke Funaoka; Takako Watanabe; Sayuri Nitta; Kei Kiyohashi; Seishin Azuma; Sei Kakinuma; Kiichiro Tsuchiya; Michio Imamura; Nobuhiko Hiraga; Kazuaki Chayama; Mamoru Watanabe
IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones.
Virology 2010;407(1):80-90.
2010: Ayaka Sakano; Hideo Yanai; Eiki Sakaguchi; Yukari Tanioka; Noboru Yahara; Hiroto Hayashi; Tomoyuki Murakami; Kazuaki Chayama
Clinical impact of tumor invasion depth staging of esophageal squamous cell carcinoma using endoscopic ultrasonography.
Hepato-gastroenterology 2010;57(104):1423-9.
2010: Yoshito Takemura; Shigeto Yoshida; Shinji Tanaka; Keiichi Onji; Shiro Oka; Toru Tamaki; Kazufumi Kaneda; Masaharu Yoshihara; Kazuaki Chayama
Quantitative analysis and development of a computer-aided system for identification of regular pit patterns of colorectal lesions.
Gastrointestinal endoscopy 2010;72(5):1047-51.
2010: Tomokazu Kawaoka; Mikiya Kitamoto; Toshio Nakanishi; Shoichi Takahashi; Shintaro Takaki; Junko Tanaka; Koji Waki; Yoshimasa Hashimoto; Masashi Hieda; Akira Hiramatsu; Masaki Ishikawa; Hideaki Kakizawa; Koji Kamada; Yoshio Katamura; Hiroshi Aikata; Kazuaki Chayama
Transcatheter chemoembolization for unresectable hepatocellular carcinoma and comparison of five staging systems.
Hepatology research : the official journal of the Japan Society of Hepatology 2010;40(11):1082-91.
2010: Aki Matsumoto; Shinji Tanaka; Sayaka Oba; Hiroyuki Kanao; Shiro Oka; Masaharu Yoshihara; Kazuaki Chayama
Outcome of endoscopic submucosal dissection for colorectal tumors accompanied by fibrosis.
Scandinavian journal of gastroenterology 2010;45(11):1329-37.
2010: Hideaki Kodama; Hiroshi Aikata; Shintaro Takaki; Takahiro Azakami; Yoshio Katamura; Tomokazu Kawaoka; Akira Hiramatsu; Koji Waki; Michio Imamura; Yoshiiku Kawakami; Shoichi Takahashi; Naoyuki Toyota; Katsuhide Ito; Kazuaki Chayama
Evaluation of portosystemic collaterals by MDCT-MPR imaging for management of hemorrhagic esophageal varices.
European journal of radiology 2010;76(2):239-45.
2010: Daiki Miki; Michiaki Kubo; Atsushi Takahashi; Kyong-Ah Yoon; Jeongseon Kim; Geon Kook Lee; Jae Ill Zo; Jin Soo Lee; Naoya Hosono; Takashi Morizono; Tatsuhiko Tsunoda; Naoyuki Kamatani; Kazuaki Chayama; Takashi Takahashi; Johji Inazawa; Yusuke Nakamura; Yataro Daigo
Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations.
Nature genetics 2010;42(10):893-6.
2010: Hidenori Ochi; Toshiro Maekawa; Hiromi Abe; Yasufumi Hayashida; Rikita Nakano; Michaki Kubo; Tatsuhiko Tsunoda; C Nelson Hayes; Hiromitsu Kumada; Yusuke Nakamura; Kazuaki Chayama
ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy--a genome-wide study of Japanese HCV virus patients.
Gastroenterology 2010;139(4):1190-7.
2010: Miwako Tanaka; Yasuhiko Kitadai; Michiyo Kodama; Kei Shinagawa; Tomonori Sumida; Shinji Tanaka; Naohide Oue; Wataru Yasui; Kazuaki Chayama
Potential role for vascular endothelial growth factor-D as an autocrine factor for human gastric carcinoma cells.
Cancer science 2010;101(10):2121-7.
2010: Kako Mishima; Naoya Sakamoto; Yuko Sekine-Osajima; Mina Nakagawa; Yasuhiro Itsui; Seishin Azuma; Sei Kakinuma; Kei Kiyohashi; Akiko Kitazume; Kiichiro Tsuchiya; Michio Imamura; Nobuhiko Hiraga; Kazuaki Chayama; Takaji Wakita; Mamoru Watanabe
Cell culture and in vivo analyses of cytopathic hepatitis C virus mutants.
Virology 2010;405(2):361-9.
2010: Yoshio Katamura; Hiroshi Aikata; Yoshimasa Hashimoto; Yuki Kimura; Tomokazu Kawaoka; Shintaro Takaki; Koji Waki; Akira Hiramatsu; Yoshiiku Kawakami; Shoichi Takahashi; Kazuaki Chayama
Pilot study of systemic combination therapy with S-1, an oral fluoropyrimidine, and cisplatin for hepatocellular carcinoma with extrahepatic metastases.
Hepato-gastroenterology 2010;57(102-103):1272-8.
2010: Hiroshi Ogi; Yukiko Nakano; Shumpei Niida; Keigo Dote; Yukoh Hirai; Kazuyosi Suenari; Yukiji Tonouchi; Noboru Oda; Yuko Makita; Shigeyuki Ueda; Kenta Kajihara; Katsuhiko Imai; Taijro Sueda; Kazuaki Chayama; Yasuki Kihara
Is structural remodeling of fibrillated atria the consequence of tissue hypoxia?
Circulation journal : official journal of the Japanese Circulation Society 2010;74(9):1815-21.
2010: Michiyo Kodama; Yasuhiko Kitadai; Tomonori Sumida; Mayu Ohnishi; Eiji Ohara; Miwako Tanaka; Kei Shinagawa; Shinji Tanaka; Wataru Yasui; Kazuaki Chayama
Expression of platelet-derived growth factor (PDGF)-B and PDGF-receptor β is associated with lymphatic metastasis in human gastric carcinoma.
Cancer science 2010;101(9):1984-9.
2010: Hiromi Abe; Hidenori Ochi; Toshiro Maekawa; C Nelson Hayes; Masataka Tsuge; Daiki Miki; Fukiko Mitsui; Nobuhiko Hiraga; Michio Imamura; Shoichi Takahashi; Waka Ohishi; Koji Arihiro; Michiaki Kubo; Yusuke Nakamura; Kazuaki Chayama
Common variation of IL28 affects gamma-GTP levels and inflammation of the liver in chronically infected hepatitis C virus patients.
Journal of hepatology 2010;53(3):439-43.
2010: Kiwamu Okita; Isao Sakaida; Mitsuru Okada; Akira Kaneko; Kazuaki Chayama; Michio Kato; Michio Sata; Harumasa Yoshihara; Naomasa Yoshihara; Noriyuki Ono; Yoshikazu Murawaki
A multicenter, open-label, dose-ranging study to exploratively evaluate the efficacy, safety, and dose-response of tolvaptan in patients with decompensated liver cirrhosis.
Journal of gastroenterology 2010;45(9):979-87.
2010: Sayaka Oba; Shinji Tanaka; Shiro Oka; Hiroyuki Kanao; Sigeto Yoshida; Fumio Shimamoto; Kazuaki Chayama
Characterization of colorectal tumors using narrow-band imaging magnification: combined diagnosis with both pit pattern and microvessel features.
Scandinavian journal of gastroenterology 2010;45(9):1084-92.
2010: Norio Akuta; Fumitaka Suzuki; Miharu Hirakawa; Yusuke Kawamura; Hiromi Yatsuji; Hitomi Sezaki; Yoshiyuki Suzuki; Tetsuya Hosaka; Masahiro Kobayashi; Mariko Kobayashi; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Kazuaki Chayama; Yusuke Nakamura; Hiromitsu Kumada
Amino acid substitution in hepatitis C virus core region and genetic variation near the interleukin 28B gene predict viral response to telaprevir with peginterferon and ribavirin.
Hepatology (Baltimore, Md.) 2010;52(2):421-9.
2010: Tomokazu Kawaoka; Hiroshi Aikata; Yoshio Katamura; Shintaro Takaki; Koji Waki; Akira Hiramatsu; Shoichi Takahashi; Masashi Hieda; Hideaki Kakizawa; Kazuaki Chayama
Hypersensitivity reactions to transcatheter chemoembolization with cisplatin and Lipiodol suspension for unresectable hepatocellular carcinoma.
Journal of vascular and interventional radiology : JVIR 2010;21(8):1219-25.
2010: Yuichi Fujii; Junko Soga; Shuji Nakamura; Takayuki Hidaka; Takaki Hata; Naomi Idei; Noritaka Fujimura; Kenji Nishioka; Kazuaki Chayama; Yasuki Kihara; Yukihito Higashi
Classification of corkscrew collaterals in thromboangiitis obliterans (Buerger's disease): relationship between corkscrew type and prevalence of ischemic ulcers.
Circulation journal : official journal of the Japanese Circulation Society 2010;74(8):1684-8.
2010: Fukiko Mitsui; Masataka Tsuge; Takashi Kimura; Shosuke Kitamura; Hiromi Abe; Hiromi Saneto; Tomokazu Kawaoka; Daiki Miki; Tsuyoshi Hatakeyama; Nobuhiko Hiraga; Michio Imamura; Yoshiiku Kawakami; Hiroshi Aikata; Shoichi Takahashi; C Nelson Hayes; Harue Igarashi; Kentaro Morimoto; Masao Shimizu; Kazuaki Chayama
Importance of serum concentration of adefovir for Lamivudine-adefovir combination therapy in patients with lamivudine-resistant chronic hepatitis B.
Antimicrobial agents and chemotherapy 2010;54(8):3205-11.
2010: Hiroki Teragawa; Naoya Mitsuba; Kenji Nishioka; Kentaro Ueda; Shingo Kono; Yukihito Higashi; Kazuaki Chayama; Yasuki Kihara
Impaired coronary microvascular endothelial function in men with metabolic syndrome.
World journal of cardiology 2010;2(7):205-10.
2010: Yoshitaka Ueno; Shinji Tanaka; Kazuaki Chayama
Non-polypoid colorectal neoplasms in ulcerative colitis.
Gastrointestinal endoscopy clinics of North America 2010;20(3):525-42.
2010: Koji Waki; Kumiko Anno; Taeko Ono; Toshinori Ide; Kazuaki Chayama; Hidetoshi Tahara
Establishment of functional telomerase immortalized human hepatocytes and a hepatic stellate cell line for telomere-targeting anticancer drug development.
Cancer science 2010;101(7):1678-85.
2010: Masataka Tsuge; Nobuhiko Hiraga; Rie Akiyama; Sachi Tanaka; Miyuki Matsushita; Fukiko Mitsui; Hiromi Abe; Shosuke Kitamura; Tsuyoshi Hatakeyama; Takashi Kimura; Daiki Miki; Nami Mori; Michio Imamura; Shoichi Takahashi; C Nelson Hayes; Kazuaki Chayama
HBx protein is indispensable for development of viraemia in human hepatocyte chimeric mice.
The Journal of general virology 2010;91(Pt 7):1854-64.
2010: Naohiro Kamiya; Eiji Iwao; Nobuhiko Hiraga; Masataka Tsuge; Michio Imamura; Shoichi Takahashi; Shinji Miyoshi; Chise Tateno; Katsutoshi Yoshizato; Kazuaki Chayama
Practical evaluation of a mouse with chimeric human liver model for hepatitis C virus infection using an NS3-4A protease inhibitor.
The Journal of general virology 2010;91(Pt 7):1668-77.
2010: Yuki Kimura; Hideyuki Hyogo; Sho-ichi Yamagishi; Masayoshi Takeuchi; Tomokazu Ishitobi; Yoshitaka Nabeshima; Koji Arihiro; Kazuaki Chayama
Atorvastatin decreases serum levels of advanced glycation endproducts (AGEs) in nonalcoholic steatohepatitis (NASH) patients with dyslipidemia: clinical usefulness of AGEs as a biomarker for the attenuation of NASH.
Journal of gastroenterology 2010;45(7):750-7.
2010: Waka Ohishi; Kazuaki Chayama
[Hepatitis C virus RNA and nucleic acid testing].
Nihon rinsho. Japanese journal of clinical medicine 2010;68 Suppl 6():450-3.
2010: Osamu Yokosuka; Koichi Takaguchi; Shinichi Fujioka; Michiko Shindo; Kazuaki Chayama; Haruhiko Kobashi; Norio Hayashi; Chifumi Sato; Kendo Kiyosawa; Kyuichi Tanikawa; Hiroki Ishikawa; Nobuyuki Masaki; Taku Seriu; Masao Omata
Long-term use of entecavir in nucleoside-naïve Japanese patients with chronic hepatitis B infection.
Journal of hepatology 2010;52(6):791-9.
2010: Yoshio Katamura; Hiroshi Aikata; Yuki Kimura; Tomokazu Kawaoka; Shintaro Takaki; Koji Waki; Akira Hiramatsu; Yoshiiku Kawakami; Shoichi Takahashi; Masaki Ishikawa; Masashi Hieda; Hideaki Kakizawa; Kazuaki Chayama
Intra-arterial 5-fluorouracil/interferon combination therapy for hepatocellular carcinoma with portal vein tumor thrombosis and extrahepatic metastases.
Journal of gastroenterology and hepatology 2010;25(6):1117-22.
2010: Takayuki Hidaka; Keigo Nakagawa; Chikara Goto; Junko Soga; Yuichi Fujii; Takaki Hata; Naomi Idei; Noritaka Fujimura; Kazuaki Chayama; Yasuki Kihara; Yukihito Higashi
Pioglitazone improves endothelium-dependent vasodilation in hypertensive patients with impaired glucose tolerance in part through a decrease in oxidative stress.
Atherosclerosis 2010;210(2):521-4.
2010: Masataka Tsuge; Chiemi Noguchi; Rie Akiyama; Miyuki Matsushita; Kana Kunihiro; Sachi Tanaka; Hiromi Abe; Fukiko Mitsui; Shosuke Kitamura; Tsuyoshi Hatakeyama; Takashi Kimura; Daiki Miki; Nobuhiko Hiraga; Michio Imamura; Shoichi Takahashi; C Nelson Hayses; Kazuaki Chayama
G to A hypermutation of TT virus.
Virus research 2010;149(2):211-6.
2010: Shiro Oka; Shinji Tanaka; Shigeto Yoshida; Toru Hiyama; Yoshitaka Ueno; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Kazuaki Chayama
A water-soluble extract from culture medium of Ganoderma lucidum mycelia suppresses the development of colorectal adenomas.
Hiroshima journal of medical sciences 2010;59(1):1-6.
2010: Yukiko Nakano; Wataru Shimizu; Hiroshi Ogi; Kazuyoshi Suenari; Noboru Oda; Yuko Makita; Kenta Kajihara; Yukoh Hirai; Akinori Sairaku; Takehito Tokuyama; Yukiji Tonouchi; Shigeyuki Ueda; Taijiro Sueda; Kazuaki Chayama; Yasuki Kihara
A spontaneous Type 1 electrocardiogram pattern in lead V2 is an independent predictor of ventricular fibrillation in Brugada syndrome.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2010;12(3):410-6.
2010: Koji Waki; Hiroshi Aikata; Yoshio Katamura; Tomokazu Kawaoka; Shintaro Takaki; Akira Hiramatsu; Shoichi Takahashi; Naoyuki Toyota; Katsuhide Ito; Kazuaki Chayama
Percutaneous radiofrequency ablation as first-line treatment for small hepatocellular carcinoma: results and prognostic factors on long-term follow up.
Journal of gastroenterology and hepatology 2010;25(3):597-604.
2010: Yoshimasa Hashimoto; Kazuaki Chayama
[Angiomyolipoma].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2010;107(2):285-6, 288.
2010: Hiroki Teragawa; Koichi Morita; Hiroki Shishido; Nobuaki Otsuka; Yutaka Hirokawa; Kazuaki Chayama; Nagara Tamaki; Yasuki Kihara
Impaired myocardial blood flow reserve in subjects with metabolic syndrome analyzed using positron emission tomography and N-13 labeled ammonia.
European journal of nuclear medicine and molecular imaging 2010;37(2):368-76.
2010: Yukihito Higashi; Hidehiro Matsuoka; Hidekazu Umei; Ryo Sugano; Yuichi Fujii; Junko Soga; Yasuki Kihara; Kazuaki Chayama; Tsutomu Imaizumi
Endothelial function in subjects with isolated low HDL cholesterol: role of nitric oxide and circulating progenitor cells.
American journal of physiology. Endocrinology and metabolism 2010;298(2):E202-9.
2010: Tatsuma Fukuhara; Toru Hiyama; Shinji Tanaka; Shiro Oka; Masaharu Yoshihara; Koji Arihiro; Kazuaki Chayama
Characteristics of esophageal squamous cell carcinomas and lugol-voiding lesions in patients with head and neck squamous cell carcinoma.
Journal of clinical gastroenterology 2010;44(2):e27-33.
2010: Kikuko Hotta; Hideyuki Hyogo; Seiho Mizusawa; Atsushi Nakajima; Kazuwa Nakao; Hidenori Ochi; Takato Ueno; Masato Yoneda; Kazuaki Chayama; Akhiro Sekine
Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease.
BMC medical genetics 2010;11():172.
2010: Shosuke Kitamura; Masataka Tsuge; Tsuyoshi Hatakeyama; Hiromi Abe; Michio Imamura; Nami Mori; Hiromi Saneto; Tomokazu Kawaoka; Fukiko Mitsui; Nobuhiko Hiraga; Shintaro Takaki; Yoshiiku Kawakami; Hiroshi Aikata; Shoichi Takahashi; Waka Ohishi; Hidenori Ochi; C Nelson Hayes; Kazuaki Chayama
Amino acid substitutions in core and NS5A regions of the HCV genome can predict virological decrease with pegylated interferon plus ribavirin therapy.
Antiviral therapy 2010;15(8):1087-97.
2010: T Shimomura; Toru Hiyama; Shinji Tanaka; Masaharu Yoshihara; Koji Arihiro; Kazuaki Chayama
Synchronous and subsequent lesions of serrated adenomas and tubular adenomas of the colorectum.
Pathobiology : journal of immunopathology, molecular and cellular biology 2010;77(5):273-7.
2010: Tatsuya Ide; Michio Sata; Kazuaki Chayama; Michiko Shindo; Joji Toyota; Satoshi Mochida; Eiichi Tomita; Hiromitsu Kumada; Gotaro Yamada; Hiroshi Yatsuhashi; Norio Hayashi; Hiroki Ishikawa; Taku Seriu; Masao Omata
Evaluation of long-term entecavir treatment in stable chronic hepatitis B patients switched from lamivudine therapy.
Hepatology international 2010;4(3):594-600.
2010: Yi-Wen Huang; Kazuaki Chayama; Masataka Tsuge; Shoichi Takahashi; Tsuyoshi Hatakeyama; Hiromi Abe; Jui-Ting Hu; Chun-Jen Liu; Ming-Yang Lai; Ding-Shinn Chen; Sien-Sing Yang; Jia-Horng Kao
Differential effects of interferon and lamivudine on serum HBV RNA inhibition in patients with chronic hepatitis B.
Antiviral therapy 2010;15(2):177-84.
2010: Hiromitsu Kumada; Hisataka Moriwaki; Hideyuki Nomura; Takeshi Okanoue; Makoto Oketani; Morikazu Onji; Shotaro Sakisaka; Masataka Seike; Fumitaka Suzuki; Tetsuo Takehara; Eiji Tanaka; Joji Toyota; Yoshiyuki Ueno; Kentaro Yoshioka; Hiroshi Yotsuyanagi; Kazuaki Chayama; Namiki Izumi
Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis C virus infection for the fiscal year 2008 in Japan.
Hepatology research : the official journal of the Japan Society of Hepatology 2010;40(1):8-13.
2010: Hiromitsu Kumada; Hisataka Moriwaki; Hideyuki Nomura; Takeshi Okanoue; Makoto Oketani; Morikazu Onji; Shotaro Sakisaka; Masataka Seike; Fumitaka Suzuki; Tetsuo Takehara; Eiji Tanaka; Joji Toyota; Yoshiyuki Ueno; Kentaro Yoshioka; Hiroshi Yotsuyanagi; Kazuaki Chayama; Namiki Izumi
Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis B virus infection for the fiscal year 2008 in Japan.
Hepatology research : the official journal of the Japan Society of Hepatology 2010;40(1):1-7.
2010: Ikue Noda; Mikiya Kitamoto; Hideki Nakahara; Ryohei Hayashi; Tomoaki Okimoto; Yoshio Monzen; Hiroyasu Yamada; Masaru Imagawa; Nobuhiko Hiraga; Junko Tanaka; Kazuaki Chayama
Regular surveillance by imaging for early detection and better prognosis of hepatocellular carcinoma in patients infected with hepatitis C virus.
Journal of gastroenterology 2010;45(1):105-12.
2010: Yukihito Higashi; Masanori Miyazaki; Chikara Goto; Hiroaki Sanada; Taijiro Sueda; Kazuaki Chayama
Sarpogrelate hydrochloride, a selective 5-hydroxytryptamine(2A) antagonist, augments autologous bone marrow mononuclear cell implantation-induced improvement in endothelium-dependent vasodilation in patients with critical limb ischemia.
Journal of cardiovascular pharmacology 2010;55(1):56-61.
2009: Toshihide Hamada; Kenji Yokota; Kiyoshi Ayada; Kazuyuki Hirai; Tomoari Kamada; Ken Haruma; Kazuaki Chayama; Keiji Oguma
Detection of Helicobacter hepaticus in human bile samples of patients with biliary disease.
Helicobacter 2009;14(6):545-51.
2009: Nobuhiko Hiraga; Michio Imamura; Tsuyoshi Hatakeyama; Shosuke Kitamura; Fukiko Mitsui; Shinji Tanaka; Masataka Tsuge; Shoichi Takahashi; Hiromi Abe; Toshiro Maekawa; Hidenori Ochi; Chise Tateno; Katsutoshi Yoshizato; Takaji Wakita; Kazuaki Chayama
Absence of viral interference and different susceptibility to interferon between hepatitis B virus and hepatitis C virus in human hepatocyte chimeric mice.
Journal of hepatology 2009;51(6):1046-54.
2009: Hiromi Abe; Hidenori Ochi; Toshiro Maekawa; Tsuyoshi Hatakeyama; Masataka Tsuge; Shosuke Kitamura; Takashi Kimura; Daiki Miki; Fukiko Mitsui; Nobuhiko Hiraga; Michio Imamura; Yoshifumi Fujimoto; Shoichi Takahashi; Yusuke Nakamura; Hiromitsu Kumada; Kazuaki Chayama
Effects of structural variations of APOBEC3A and APOBEC3B genes in chronic hepatitis B virus infection.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(12):1159-68.
2009: Masahiro Ohira; Kohei Ishiyama; Yuka Tanaka; Marlen Doskali; Yuka Igarashi; Hirotaka Tashiro; Nobuhiko Hiraga; Michio Imamura; Naoya Sakamoto; Toshimasa Asahara; Kazuaki Chayama; Hideki Ohdan
Adoptive immunotherapy with liver allograft-derived lymphocytes induces anti-HCV activity after liver transplantation in humans and humanized mice.
The Journal of clinical investigation 2009;119(11):3226-35.
2009: Yukihito Higashi; Chikara Goto; Takayuki Hidaka; Junko Soga; Shuji Nakamura; Yuichi Fujii; Takaki Hata; Naomi Idei; Noritaka Fujimura; Kazuaki Chayama; Yasuki Kihara; Akira Taguchi
Oral infection-inflammatory pathway, periodontitis, is a risk factor for endothelial dysfunction in patients with coronary artery disease.
Atherosclerosis 2009;206(2):604-10.
2009: Michiko Shindo; Kazuyuki Suzuki; Eiichi Tomita; Joji Toyota; Hirohito Tsubouchi; Osamu Yokosuka; Kazuaki Chayama; Norio Hayashi; Hiroki Ishikawa; Hiromitsu Kumada; Satoshi Mochida; Takeshi Okanoue; Michio Sata; Taku Seriu; Masao Omata
Antiviral activity, dose-response relationship, and safety of entecavir following 24-week oral dosing in nucleoside-naive Japanese adult patients with chronic hepatitis B: a randomized, double-blind, phase II clinical trial.
Hepatology international 2009;3(3):445-52.
2009: Toru Hiyama; Keitaro Matsuo; Yuji Urabe; Tatsuma Fukuhara; Shinji Tanaka; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Meta-analysis used to identify factors associated with the effectiveness of proton pump inhibitors against non-erosive reflux disease.
Journal of gastroenterology and hepatology 2009;24(8):1326-32.
2009: Hiroyuki Tahara; Yuka Tanaka; Kohei Ishiyama; Kentaro Ide; Masayuki Shishida; Toshimitsu Irei; Yuichiro Ushitora; Masahiro Ohira; Masataka Banshodani; Hirotaka Tashiro; Toshiyuki Itamoto; Toshimasa Asahara; Michio Imamura; Shoichi Takahashi; Kazuaki Chayama; Hideki Ohdan
Successful hepatitis B vaccination in liver transplant recipients with donor-specific hyporesponsiveness.
Transplant international : official journal of the European Society for Organ Transplantation 2009;22(8):805-13.
2009: Takuya Matsumura; Zongyi Hu; Takanobu Kato; Marlene Dreux; Yong-Yuan Zhang; Michio Imamura; Nobuhiko Hiraga; Jean-Marc Juteau; Francois-Loic Cosset; Kazuaki Chayama; Andrew Vaillant; TSANYANG LIANG
Amphipathic DNA polymers inhibit hepatitis C virus infection by blocking viral entry.
Gastroenterology 2009;137(2):673-81.
2009: Shiro Oka; Shinji Tanaka; Hiroyuki Kanao; Sayaka Oba; Kazuaki Chayama
Therapeutic strategy for colorectal laterally spreading tumor.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2009;21 Suppl 1():S43-6.
2009: Shinji Tanaka; Shiro Oka; Kazuaki Chayama; Koichi Kawashima
Knack and practical technique of colonoscopic treatment focused on endoscopic mucosal resection using snare.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2009;21 Suppl 1():S38-42.
2009: Hiroshi Yotsuyanagi; Yoshimi Kikuchi; Kunihisa Tsukada; Kyouji Nishida; Michio Kato; Hironori Sakai; Junki Takamatsu; Shuhei Hige; Kazuaki Chayama; Kyoji Moriya; Kazuhiko Koike
Chronic hepatitis C in patients co-infected with human immunodeficiency virus in Japan: a retrospective multicenter analysis.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(7):657-63.
2009: Tomokazu Kawaoka; Hiroshi Aikata; Shintaro Takaki; Yoshio Katamura; Akira Hiramatsu; Koji Waki; Shoichi Takahashi; Masashi Hieda; Naoyuki Toyota; Katsuhide Ito; Kazuaki Chayama
Transarterial infusion chemotherapy using cisplatin-lipiodol suspension with or without embolization for unresectable hepatocellular carcinoma.
Cardiovascular and interventional radiology 2009;32(4):687-94.
2009: Nwe Nwe Soe; Takafumi Ishida; Mari Ishida; Mariko Sawano; Keiko Abe; Narimasa Miho; Kazuaki Chayama; Yasuki Kihara; Masao Yoshizumi
Nifedipine interferes with migration of vascular smooth muscle cells via inhibition of Pyk2-Src axis.
Journal of atherosclerosis and thrombosis 2009;16(3):230-8.
2009: Chiemi Noguchi; Michio Imamura; Masataka Tsuge; Nobuhiko Hiraga; Nami Mori; Daiki Miki; Takashi Kimura; Shoichi Takahashi; Yoshifumi Fujimoto; Hidenori Ochi; Hiromi Abe; Toshiro Maekawa; Chise Tateno; Katsutoshi Yoshizato; Kazuaki Chayama
G-to-A hypermutation in hepatitis B virus (HBV) and clinical course of patients with chronic HBV infection.
The Journal of infectious diseases 2009;199(11):1599-607.
2009: Yoshitaka Nabeshima; Susumu Tazuma; Keishi Kanno; Hideyuki Hyogo; Kazuaki Chayama
Deletion of angiotensin II type I receptor reduces hepatic steatosis.
Journal of hepatology 2009;50(6):1226-35.
2009: Tomonori Sumida; Yasuhiko Kitadai; Toru Hiyama; Kei Shinagawa; Miwako Tanaka; Michiyo Kodama; Hiroshi Masuda; Masanori Ito; Shinji Tanaka; Masaharu Yoshihara; Kazuaki Chayama
Antibodies to Helicobacter pylori and CagA protein are associated with the response to antibacterial therapy in patients with H. pylori-positive API2-MALT1-negative gastric MALT lymphoma.
Cancer science 2009;100(6):1075-81.
2009: Keiji Tsuji; Yoshiiku Kawakami; Shiomi Aimitsu; Hiroshi Kohno; Yasuyuki Aisaka; Shigeru Kimura; Shinji Nagata; Hiroaki Ohgoshi; Mikiya Kitamoto; Tohru Hidaka; Hiroiku Kawakami; Toshio Nakanishi; Kazuaki Chayama
Predicting the response to 48-week combination therapy with peginterferon alpha-2b plus ribavirin from the estimated HCV RNA load index after negative serum change in genotype 1b hepatitis C patients.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(6):531-8.
2009: Yoshihiro Wada; Masanori Ito; Shunsuke Takata; Shosuke Kitamura; Akemi Takamura; Masana Tatsugami; Shinobu Imagawa; Yoshiaki Matsumoto; Shinji Tanaka; Masaharu Yoshihara; Kazuaki Chayama
Little necessity of acid inhibition against proton pump inhibitor rebound effects and prior helicobacter pylori eradication therapy in gastric ulcer patients: a randomized prospective study.
Hepato-gastroenterology 2009;56(91-92):624-8.
2009: Takako Tsumura; Shintaro Takaki; Hiroshi Aikata; Yuki Kimura; Yoshio Katamura; Takahiro Azakami; Tomokazu Kawaoka; Masataka Tsuge; Hiromi Sanetou; Koji Waki; Akira Hiramatsu; Michio Imamura; Yoshiiku Kawakami; Shoichi Takahashi; Koji Arihiro; Kazuaki Chayama
[Case of double cancer of the liver, cholangiocarcinoma and hepatocellular carcinoma detected in a patient with hepatitis C 13 years after diminution of HCV-RNA by interferon treatment].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2009;106(5):674-83.
2009: Yoichiro Kamatani; Sukanya Wattanapokayakit; Hidenori Ochi; Takahisa Kawaguchi; Atsushi Takahashi; Naoya Hosono; Michiaki Kubo; Tatsuhiko Tsunoda; Naoyuki Kamatani; Hiromitsu Kumada; Aekkachai Puseenam; Thanyachai Sura; Yataro Daigo; Kazuaki Chayama; Wasun Chantratita; Yusuke Nakamura; Koichi Matsuda
A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.
Nature genetics 2009;41(5):591-5.
2009: Hironobu Tsukada; Hidenori Ochi; Toshiro Maekawa; Hiromi Abe; Yoshifumi Fujimoto; Masataka Tsuge; Hiroshi Takahashi; Hiromitsu Kumada; Naoyuki Kamatani; Yusuke Nakamura; Kazuaki Chayama
A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C.
Gastroenterology 2009;136(5):1796-805.e6.
2009: Ritsuo Mouri; Shigeto Yoshida; Shinji Tanaka; Shiro Oka; Masaharu Yoshihara; Kazuaki Chayama
Evaluation and validation of computed virtual chromoendoscopy in early gastric cancer.
Gastrointestinal endoscopy 2009;69(6):1052-8.
2009: Y Urabe; T Hiyama; Shinji Tanaka; Shiro Oka; Masaharu Yoshihara; Koji Arihiro; Kazuaki Chayama
Metachronous multiple esophageal squamous cell carcinomas and Lugol-voiding lesions after endoscopic mucosal resection.
Endoscopy 2009;41(4):304-9.
2009: Shuji Nakamura; Masashi Kimura; Chikara Goto; Kensuke Noma; Masao Yoshizumi; Kazuaki Chayama; Yasuki Kihara; Yukihito Higashi
Cigarette smoking abolishes ischemic preconditioning-induced augmentation of endothelium-dependent vasodilation.
Hypertension 2009;53(4):674-81.
2009: Nami Mori; Michio Imamura; Yoshiiku Kawakami; Hiromi Saneto; Tomokazu Kawaoka; Shintaro Takaki; Hiroshi Aikata; Shoichi Takahashi; Kazuaki Chayama
Randomized trial of high-dose interferon-alpha-2b combined with ribavirin in patients with chronic hepatitis C: Correlation between amino acid substitutions in the core/NS5A region and virological response to interferon therapy.
Journal of medical virology 2009;81(4):640-9.
2009: Toru Hiyama; Masaharu Yoshihara; Shinji Tanaka; Ken Haruma; Kazuaki Chayama
Effectiveness of prokinetic agents against diseases external to the gastrointestinal tract.
Journal of gastroenterology and hepatology 2009;24(4):537-46.
2009: Yoshio Katamura; Hiroshi Aikata; Yuki Kimura; Takahiro Azakami; Tomokazu Kawaoka; Shintaro Takaki; Koji Waki; Akira Hiramatsu; Yoshiiku Kawakami; Shoichi Takahashi; Kazuaki Chayama
Successful treatment of pulmonary metastases associated with advanced hepatocellular carcinoma by systemic 5-fluorouracil combined with interferon-alpha in a hemodialysis patient.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(4):415-20.
2009: Akira Fukumoto; Shinji Tanaka; Takayoshi Shishido; Yoshito Takemura; Shiro Oka; Kazuaki Chayama
Comparison of detectability of small-bowel lesions between capsule endoscopy and double-balloon endoscopy for patients with suspected small-bowel disease.
Gastrointestinal endoscopy 2009;69(4):857-65.
2009: Ritsuo Mouri; Shigeto Yoshida; Shinji Tanaka; Shiro Oka; Masaharu Yoshihara; Kazuaki Chayama
Usefulness of endoscopic ultrasonography in determining the depth of invasion and indication for endoscopic treatment of early gastric cancer.
Journal of clinical gastroenterology 2009;43(4):318-22.
2009: Fukiko Mitsui; Hiroshi Aikata; Takahiro Azakami; Yoshio Katamura; Takashi Kimura; Tomokazu Kawaoka; Hiromi Saneto; Shintaro Takaki; Nobuhiko Hiraga; Masataka Tsuge; Koji Waki; Akira Hiramatsu; Michio Imamura; Yoshiiku Kawakami; Shoichi Takahashi; Koji Arihiro; Kazuaki Chayama
The first Japanese case of COACH syndrome.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(3):318-23.
2009: Hiroyuki Kanao; Shinji Tanaka; Shiro Oka; Mayuko Hirata; Shigeto Yoshida; Kazuaki Chayama
Narrow-band imaging magnification predicts the histology and invasion depth of colorectal tumors.
Gastrointestinal endoscopy 2009;69(3 Pt 2):631-6.
2009: Tomokazu Kawaoka; Yoshiiku Kawakami; Keiji Tsuji; Hiroyuki Ito; Mikiya Kitamoto; Shiomi Aimitsu; Hiroiku Kawakami; Soo Cheol Jeong; Michio Imamura; Hiroshi Aikata; Shoichi Takahashi; Kazuaki Chayama
Dose comparison study of pegylated interferon-alpha-2b plus ribavirin in naïve Japanese patients with hepatitis C virus genotype 2: a randomized clinical trial.
Journal of gastroenterology and hepatology 2009;24(3):366-71.
2009: Tomokazu Kawaoka; Hiroshi Aikata; Shintaro Takaki; Kiminori Uka; Takahiro Azakami; Hiromi Saneto; Soo Cheol Jeong; Yoshiiku Kawakami; Shoichi Takahashi; Naoyuki Toyota; Katsuhide Ito; Yutaka Hirokawa; Kazuaki Chayama
FDG positron emission tomography/computed tomography for the detection of extrahepatic metastases from hepatocellular carcinoma.
Hepatology research : the official journal of the Japan Society of Hepatology 2009;39(2):134-42.
2009: Masahiro Ohira; Minoru Ishifuro; Kentaro Ide; Toshimitsu Irei; Hirotaka Tashiro; Toshiyuki Itamoto; Katsuhide Ito; Kazuaki Chayama; Toshimasa Asahara; Hideki Ohdan
Significant correlation between spleen volume and thrombocytopenia in liver transplant patients: a concept for predicting persistent thrombocytopenia.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2009;15(2):208-15.
2009: Toshiki Yamaguchi; Shigeto Yoshida; Shinji Tanaka; Yoshito Takemura; Shiro Oka; Masaharu Yoshihara; Hiroyasu Yamada; Kazuaki Chayama
Predicting the clinical response to cytapheresis in steroid-refractory or -dependent ulcerative colitis using contrast-enhanced ultrasonography.
Scandinavian journal of gastroenterology 2009;44(7):831-7.
2009: Yoshiaki Matsumoto; Masanori Ito; Masataka Tsuge; Taiji Matsuo; Shinji Tanaka; Ken Haruma; Kazuaki Chayama
Ecabet sodium induces neuronal nitric oxide synthase-derived nitric oxide synthesis and gastric adaptive relaxation in the human stomach.
Journal of gastroenterology 2009;44(11):1118-24.
2009: Takeshi Okanoue; Yoshito Itoh; Hiroaki Hashimoto; Kohichiroh Yasui; Masahito Minami; Tetsuo Takehara; Eiji Tanaka; Morikazu Onji; Joji Toyota; Kazuaki Chayama; Kentaro Yoshioka; Namiki Izumi; Norio Akuta; Hiromitsu Kumada
Predictive values of amino acid sequences of the core and NS5A regions in antiviral therapy for hepatitis C: a Japanese multi-center study.
Journal of gastroenterology 2009;44(9):952-63.
2009: Shunsuke Takata; Masanori Ito; Yoshihiro Wada; Masaharu Yoshihara; Shinji Tanaka; Kazuaki Chayama
Pathogenetic role of the tyrosine-phosphorylated CagA EPIYA sequence of Helicobacter pylori in histological gastritis in Japanese patients.
Journal of gastroenterology 2009;44(5):405-11.
2009: Masanori Ito; Shunsuke Takata; Masana Tatsugami; Yoshihiro Wada; Shinobu Imagawa; Yoshiaki Matsumoto; Akemi Takamura; Shosuke Kitamura; Taiji Matsuo; Shinji Tanaka; Ken Haruma; Kazuaki Chayama
Clinical prevention of gastric cancer by Helicobacter pylori eradication therapy: a systematic review.
Journal of gastroenterology 2009;44(5):365-71.
2009: Yoshio Katamura; Hiroshi Aikata; Shintaro Takaki; Takahiro Azakami; Tomokazu Kawaoka; Koji Waki; Akira Hiramatsu; Yoshiiku Kawakami; Shoichi Takahashi; Masahiro Kenjo; Naoyuki Toyota; Katsuhide Ito; Kazuaki Chayama
Intra-arterial 5-fluorouracil/interferon combination therapy for advanced hepatocellular carcinoma with or without three-dimensional conformal radiotherapy for portal vein tumor thrombosis.
Journal of gastroenterology 2009;44(5):492-502.
2009: Daizaburo Hirata; Takumi Yamabuki; Daiki Miki; Tomoo Ito; Eiju Tsuchiya; Masahiro Fujita; Masao Hosokawa; Kazuaki Chayama; Yusuke Nakamura; Yataro Daigo
Involvement of epithelial cell transforming sequence-2 oncoantigen in lung and esophageal cancer progression.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(1):256-66.
2009: Akira Fukumoto; Shinji Tanaka; Hiroki Imagawa; Takayoshi Shishido; Shiro Oka; Shigeto Yoshida; Hiroyasu Yamada; Kazuaki Chayama
Usefulness and limitations of transabdominal ultrasonography for detecting small-bowel tumors.
Scandinavian journal of gastroenterology 2009;44(3):332-8.
2008: Bunjiro Noma; Tamito Sasaki; Yoshifumi Fujimoto; Masahiro Serikawa; Kenso Kobayashi; Motoki Inoue; Hiroshi Itsuki; Michihiro Kamigaki; Tomoyuki Minami; Kazuaki Chayama
Expression of multidrug resistance-associated protein 2 is involved in chemotherapy resistance in human pancreatic cancer.
International journal of oncology 2008;33(6):1187-94.
2008: Hideyuki Hyogo; Susumu Tazuma; Koji Arihiro; Keiko Iwamoto; Yoshitaka Nabeshima; Motoki Inoue; Tomokazu Ishitobi; Michihiro Nonaka; Kazuaki Chayama
Efficacy of atorvastatin for the treatment of nonalcoholic steatohepatitis with dyslipidemia.
Metabolism: clinical and experimental 2008;57(12):1711-8.
2008: Michiyo Kodama; Yasuhiko Kitadai; Miwako Tanaka; Toshio Kuwai; Shinji Tanaka; Naohide Oue; Wataru Yasui; Kazuaki Chayama
Vascular endothelial growth factor C stimulates progression of human gastric cancer via both autocrine and paracrine mechanisms.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(22):7205-14.
2008: Tsuyoshi Kuroda; Masanori Ito; Yoshihiro Wada; Yasuhiko Kitadai; Shinji Tanaka; Kazuhiro Yoshida; Masaharu Yoshihara; Ken Haruma; Sven Merdh; Kazuaki Chayama
Presence of poorly differentiated component correlated with submucosal invasion in the early diffuse-type gastric cancer.
Hepato-gastroenterology 2008;55(88):2264-8.
2008: Takashi Umemura; Junko Soga; Takayuki Hidaka; Hiroaki Takemoto; Shuji Nakamura; Daisuke Jitsuiki; Kenji Nishioka; Chikara Goto; Hiroki Teragawa; Masao Yoshizumi; Kazuaki Chayama; Yukihito Higashi
Aging and hypertension are independent risk factors for reduced number of circulating endothelial progenitor cells.
American journal of hypertension 2008;21(11):1203-9.
2008: Madoka Nakao; Shigeto Yoshida; Shinji Tanaka; Yoshito Takemura; Shiro Oka; Masaharu Yoshihara; Kazuaki Chayama
Optical biopsy of early gastroesophageal cancer by catheter-based reflectance-type laser-scanning confocal microscopy.
Journal of biomedical optics 2008;13(5):054043.
2008: Takashi Kimura; Michio Imamura; Nobuhiko Hiraga; Tsuyoshi Hatakeyama; Daiki Miki; Chiemi Noguchi; Nami Mori; Masataka Tsuge; Shoichi Takahashi; Yoshifumi Fujimoto; Eiji Iwao; Hidenori Ochi; Hiromi Abe; Toshiro Maekawa; Keiko Arataki; Chise Tateno; Katsutoshi Yoshizato; Takaji Wakita; Toru Okamoto; Y Matsuura; Kazuaki Chayama
Establishment of an infectious genotype 1b hepatitis C virus clone in human hepatocyte chimeric mice.
The Journal of general virology 2008;89(Pt 9):2108-13.
2008: Akira Hiramatsu; Shoichi Takahashi; Hiroshi Aikata; Takahiro Azakami; Yoshio Katamura; Tomokazu Kawaoka; Kiminori Uka; Keitaro Yamashina; Shintaro Takaki; Hideaki Kodama; Soo Cheol Jeong; Michio Imamura; Yoshiiku Kawakami; Kazuaki Chayama
Etiology and outcome of acute liver failure: retrospective analysis of 50 patients treated at a single center.
Journal of gastroenterology and hepatology 2008;23(8 Pt 1):1216-22.
2008: Junko Soga; Shuji Nakamura; Kenji Nishioka; Takashi Umemura; Daisuke Jitsuiki; Takayuki Hidaka; Hiroki Teragawa; Hiroaki Takemoto; Chikara Goto; Masao Yoshizumi; Kazuaki Chayama; Yukihito Higashi
Relationship between augmentation index and flow-mediated vasodilation in the brachial artery.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(7):1293-8.
2008: Hiroki Teragawa; Kentaro Ueda; Koichiro Okuhara; Rieko Kuwashima; Yukihiro Fukuda; Masao Kiguchi; Kingo Taniguchi; Yukihito Higashi; Tetsuya Oshima; Masao Yoshizumi; Kazuaki Chayama
Coronary vasospasm produces reversible perfusion defects observed during adenosine triphosphate stress myocardial single-photon emission computed tomography.
Clinical cardiology 2008;31(7):310-6.
2008: Akira Fukumoto; Shinji Tanaka; Takayoshi Shishido; Shiro Oka; Kazuaki Chayama
[Diagnosis and treatment for benign small bowel tumor].
Nihon rinsho. Japanese journal of clinical medicine 2008;66(7):1305-11.
2008: Shinobu Imagawa; Masaharu Yoshihara; Masanori Ito; Shigeto Yoshida; Yoshihiro Wada; Masana Tatsugami; Akemi Takamura; Shinji Tanaka; Ken Haruma; Kazuaki Chayama
Evaluation of gastric cancer risk using topography of histological gastritis: a large-scaled cross-sectional study.
Digestive diseases and sciences 2008;53(7):1818-23.
2008: Michihiro Nonaka; Susumu Tazuma; Hideyuki Hyogo; Keishi Kanno; Kazuaki Chayama
Cytoprotective effect of tauroursodeoxycholate on hepatocyte apoptosis induced by peroxisome proliferator-activated receptor gamma ligand.
Journal of gastroenterology and hepatology 2008;23(7 Pt 2):e198-206.
2008: Harumi Ohtani; Tetsuji Shingu; Kazuaki Chayama; Kozo Hayashi
Different role of macrophages and vascular smooth muscle cells in atherosclerotic lesions of Watanabe heritable hyperlipidemic (WHHL) rabbit between aorta and coronary artery.
Hiroshima journal of medical sciences 2008;57(2):53-60.
2008: Yoshiyuki Yamamoto; Yuichiro Watari; Andrei Brydun; Masao Yoshizumi; Masahiro Akishita; Masatsugu Horiuchi; Kazuaki Chayama; Tetsuya Oshima; Ryoji Ozono
Role of the angiotensin II type 2 receptor in arterial remodeling after wire injury in mice.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(6):1241-9.
2008: Toru Hiyama; Masaharu Yoshihara; Shinji Tanaka; Ken Haruma; Kazuaki Chayama
Strategy for treatment of nonerosive reflux disease in Asia.
World journal of gastroenterology : WJG 2008;14(20):3123-8.
2008: Keiko Abe; Hidekatsu Nakashima; Mari Ishida; Narimasa Miho; Mariko Sawano; Nwe Nwe Soe; Masahiko Kurabayashi; Kazuaki Chayama; Masao Yoshizumi; Takafumi Ishida
Angiotensin II-induced osteopontin expression in vascular smooth muscle cells involves Gq/11, Ras, ERK, Src and Ets-1.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(5):987-98.
2008: Toru Hiyama; Masaharu Yoshihara; Shinji Tanaka; Kazuaki Chayama
Genetic polymorphisms and head and neck cancer risk (Review).
International journal of oncology 2008;32(5):945-73.
2008: Kiminori Uka; Hiroshi Aikata; Shintaro Takaki; Tomokazu Kawaoka; Hiromi Saneto; Daiki Miki; Shoichi Takahashi; Naoyuki Toyota; Katsuhide Ito; Kazuaki Chayama
Systemic gemcitabine combined with intra-arterial low-dose cisplatin and 5-fluorouracil for advanced hepatocellular carcinoma: seven cases.
World journal of gastroenterology : WJG 2008;14(16):2602-8.
2008: Yuichiro Watari; Yoshiyuki Yamamoto; Andrei Brydun; Takafumi Ishida; Shinji Mito; Masao Yoshizumi; Kazuhiko Igarashi; Kazuaki Chayama; Tetsuya Ohshima; Ryoji Ozono
Ablation of the bach1 gene leads to the suppression of atherosclerosis in bach1 and apolipoprotein E double knockout mice.
Hypertension research : official journal of the Japanese Society of Hypertension 2008;31(4):783-92.
2008: Waka Ohishi; Saeko Fujiwara; John B Cologne; Gen Suzuki; Masazumi Akahoshi; Nobuo Nishi; Ikuno Takahashi; Kazuaki Chayama
Risk factors for hepatocellular carcinoma in a Japanese population: a nested case-control study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(4):846-54.
2008: Soocheol Jeong; Yoshiiku Kawakami; Mikiya Kitamoto; Hiroto Ishihara; Keiji Tsuji; Shiomi Aimitsu; Hiroiku Kawakami; Kiminori Uka; Shintaro Takaki; Hideaki Kodama; Koji Waki; Michio Imamura; Hiroshi Aikata; Shoichi Takahashi; Kazuaki Chayama
Prospective study of short-term peginterferon-alpha-2a monotherapy in patients who had a virological response at 2 weeks after initiation of interferon therapy.
Journal of gastroenterology and hepatology 2008;23(4):541-5.
2008: Miwako Tanaka; Yasuhiko Kitadai; Michiyo Kodama; Tomonori Sumida; Kei Shinagawa; Kyoko Yoshioka; Yutaka Mitsuoka; Hiroshi Masuda; Toru Hiyama; Shinji Tanaka; Masaharu Yoshihara; Kazuaki Chayama
[A case report of anaphylactoid purpura with acute abdominal pain secondary to trauma caused by traffic accident].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2008;105(4):566-71.
2008: M Kodama; Yasuhiko Kitadai; T Shishido; Masaru Shimamoto; Akira Fukumoto; H Masuda; Shinji Tanaka; Masaharu Yoshihara; A Sakai; H Nakayama; Kazuaki Chayama
Primary follicular lymphoma of the gastrointestinal tract: a retrospective case series.
Endoscopy 2008;40(4):343-6.
2008: Daisuke Kamino; Noriaki Manabe; Jiro Hata; Ken Haruma; Shinji Tanaka; Kazuaki Chayama
Long-term Ultrasonographic Follow-up Study of Gastric Motility in Patients with Functional Dyspepsia.
Journal of clinical biochemistry and nutrition 2008;42(2):144-9.
2008: Rie Utoh; Chise Tateno; Chihiro Yamasaki; Nobuhiko Hiraga; Miho Kataoka; Takashi Shimada; Kazuaki Chayama; Katsutoshi Yoshizato
Susceptibility of chimeric mice with livers repopulated by serially subcultured human hepatocytes to hepatitis B virus.
Hepatology (Baltimore, Md.) 2008;47(2):435-46.
2008: Yukihito Higashi; Chikara Goto; Daisuke Jitsuiki; Takashi Umemura; Kenji Nishioka; Takayuki Hidaka; Hiroaki Takemoto; Shuji Nakamura; Junko Soga; Kazuaki Chayama; Masao Yoshizumi; Akira Taguchi
Periodontal infection is associated with endothelial dysfunction in healthy subjects and hypertensive patients.
Hypertension 2008;51(2):446-53.
2008: Hiroyuki Kanao; Shinji Tanaka; Shiro Oka; Iwao Kaneko; Shigeto Yoshida; Koji Arihiro; Masaharu Yoshihara; Kazuaki Chayama
Clinical significance of type V(I) pit pattern subclassification in determining the depth of invasion of colorectal neoplasms.
World journal of gastroenterology : WJG 2008;14(2):211-7.
2008: Hiroshi Aikata; Kazuaki Chayama
[Practice of screening tests for a group of patients with a high risk of developing liver cancer].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2008;97(1):23-7.
2008: H Ishida; John Wong; K Hino; F Kurokawa; S Nishina; I Sakaida; Kiwamu Okita; Takao Tamesa; M Oka; Takuji Torimura; M Sata; S Takahashi; Kazuaki Chayama; Y Inoue
Validating a Markov model of treatment for hepatitis C virus-related hepatocellular carcinoma.
Methods of information in medicine 2008;47(6):529-40.
2008: Shinji Tanaka; Shiro Oka; Kazuaki Chayama
Colorectal endoscopic submucosal dissection: present status and future perspective, including its differentiation from endoscopic mucosal resection.
Journal of gastroenterology 2008;43(9):641-51.
2008: Kiminori Uka; Hiroshi Aikata; Nami Mori; Shintaro Takaki; Yoshiiku Kawakami; Takahiro Azakami; Tomokazu Kawaoka; Soo Cheol Jeong; Shoichi Takahashi; Kazuaki Chayama
Combination therapy of oral fluoropyrimidine anticancer drug S-1 and interferon alpha for HCC patients with extrahepatic metastases.
Oncology 2008;75(1-2):8-16.
2008: Daiki Miki; Hiroshi Aikata; Kiminori Uka; Hiromi Saneto; Tomokazu Kawaoka; Takahiro Azakami; Shintaro Takaki; Soo Cheol Jeong; Michio Imamura; Yoshiiku Kawakami; Shoichi Takahashi; Toshiyuki Itamoto; Toshimasa Asahara; Koji Arihiro; Kazuaki Chayama
Clinicopathological features of elderly patients with hepatitis C virus-related hepatocellular carcinoma.
Journal of gastroenterology 2008;43(7):550-7.
2008: Yoshiaki Matsumoto; Masanori Ito; Daisuke Kamino; Shinji Tanaka; Ken Haruma; Kazuaki Chayama
Relation between histologic gastritis and gastric motility in Japanese patients with functional dyspepsia: evaluation by transabdominal ultrasonography.
Journal of gastroenterology 2008;43(5):332-7.
2008: Kazuyoshi Suenari; Nobuo Shiode; Kinya Shirota; Hiroshige Ishii; Kenji Goto; Akinori Sairaku; Shinsuke Mikami; Yukiko Nakano; Kazuaki Chayama
Predictors and long-term prognostic implications of angiographic slow/no-flow during percutaneous coronary intervention for acute myocardial infarction.
Internal medicine (Tokyo, Japan) 2008;47(10):899-906.
2008: Keiko Iwamoto; Keishi Kanno; Hideyuki Hyogo; Sho-ichi Yamagishi; Masayoshi Takeuchi; Susumu Tazuma; Kazuaki Chayama
Advanced glycation end products enhance the proliferation and activation of hepatic stellate cells.
Journal of gastroenterology 2008;43(4):298-304.
2008: Toru Hiyama; Masaharu Yoshihara; Shinji Tanaka; Kazuaki Chayama
The number of criminal prosecutions against physicians due to medical negligence is on the rise in Japan.
The American journal of emergency medicine 2008;26(1):105-6.
2008: Madoka Nakao; Jiro Hata; Noriaki Manabe; Hideharu Okanobu; Shinji Tanaka; Ken Haruma; Kazuaki Chayama
Evaluation of colon cancer vascularity by flash echo imaging.
Scandinavian journal of gastroenterology 2008;43(2):223-8.
2007: Masaru Shimamoto; Yoshitaka Ueno; Shinji Tanaka; Toshiko Onitake; Rie Hanaoka; Kyoko Yoshioka; Tsuyoshi Hatakeyama; Kazuaki Chayama
Selective decrease in colonic CD56(+) T and CD161(+) T cells in the inflamed mucosa of patients with ulcerative colitis.
World journal of gastroenterology : WJG 2007;13(45):5995-6002.
2007: Yoshiharu Tokimitsu; Hiroyuki Kishi; Sachiko Kondo; Ritsu Honda; Kazuto Tajiri; Kazumi Motoki; Tatsuhiko Ozawa; Shinichi Kadowaki; Tsutomu Obata; Satoshi Fujiki; Chise Tateno; Hideki Takaishi; Kazuaki Chayama; Katsutoshi Yoshizato; Eiichi Tamiya; Toshiro Sugiyama; Atsushi Muraguchi
Single lymphocyte analysis with a microwell array chip.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2007;71(12):1003-10.
2007: Hiromi Yatsuji; Nobuhiko Hiraga; Nami Mori; Tsuyoshi Hatakeyama; Masataka Tsuge; Michio Imamura; Shoichi Takahashi; Yoshifumi Fujimoto; Hidenori Ochi; Hiromi Abe; Toshiro Maekawa; Fumitaka Suzuki; Hiromitsu Kumada; Kazuaki Chayama
Successful treatment of an entecavir-resistant hepatitis B virus variant.
Journal of medical virology 2007;79(12):1811-7.
2007: Yuichi Fujii; Kenji Nishioka; Masao Yoshizumi; Kazuaki Chayama; Yukihito Higashi
Images in cardiovascular medicine. Corkscrew collaterals in thromboangitis obliterans (Buerger's disease).
Circulation 2007;116(21):e539-40.
2007: Mayuko Hirata; Shinji Tanaka; Shiro Oka; Iwao Kaneko; Shigeto Yoshida; Masaharu Yoshihara; Kazuaki Chayama
Evaluation of microvessels in colorectal tumors by narrow band imaging magnification.
Gastrointestinal endoscopy 2007;66(5):945-52.
2007: Kiminori Uka; Hiroshi Aikata; Shintaro Takaki; Daiki Miki; Soo Cheol Jeong; Akira Hiramatsu; Hideaki Kodama; Hiroo Shirakawa; Yoshiiku Kawakami; Shoichi Takahashi; Naoyuki Toyota; Katsuhide Ito; Kazuaki Chayama
Similar effects of recombinant interferon-alpha-2b and natural interferon-alpha when combined with intra-arterial 5-fluorouracil for the treatment of advanced hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver 2007;27(9):1209-16.
2007: Hirotaka Tashiro; Toshiyuki Itamoto; Tamito Sasaki; Hideki Ohdan; Yasuhiro Fudaba; Hironobu Amano; Saburo Fukuda; Hideki Nakahara; Kohei Ishiyama; Akihiko Ohshita; Toshihiko Kohashi; Hiroshi Mitsuta; Kazuaki Chayama; Toshimasa Asahara
Biliary complications after duct-to-duct biliary reconstruction in living-donor liver transplantation: causes and treatment.
World journal of surgery 2007;31(11):2222-9.
2007: Soo Cheol Jeong; Hiroshi Aikata; Yoshio Katamura; Takahiro Azakami; Tomokazu Kawaoka; Hiromi Saneto; Kiminori Uka; Nami Mori; Shintaro Takaki; Hideaki Kodama; Koji Waki; Michio Imamura; Hiroo Shirakawa; Yoshiiku Kawakami; Shoichi Takahashi; Kazuaki Chayama
Effects of a 24-week course of interferon-alpha therapy after curative treatment of hepatitis C virus-associated hepatocellular carcinoma.
World journal of gastroenterology : WJG 2007;13(40):5343-50.
2007: Soocheol Jeong; Hiroshi Aikata; Yoshio Katamura; Takahiro Azakami; Tomokazu Kawaoka; Hiromi Saneto; Kiminori Uka; Nami Mori; Shintaro Takaki; Hideaki Kodama; Koji Waki; Michio Imamura; Hiroo Shirakawa; Yoshiiku Kawakami; Shoichi Takahashi; Kazuaki Chayama
Low-dose intermittent interferon-alpha therapy for HCV-related liver cirrhosis after curative treatment of hepatocellular carcinoma.
World journal of gastroenterology : WJG 2007;13(39):5188-95.
2007: Toru Hiyama; Masaharu Yoshihara; Shinji Tanaka; Kazuaki Chayama
Genetic polymorphisms and esophageal cancer risk.
International journal of cancer. Journal international du cancer 2007;121(8):1643-58.
2007: Kiminori Uka; Hiroshi Aikata; Shintaro Takaki; Daiki Miki; Tomokazu Kawaoka; Soo Cheol Jeong; Shoichi Takahashi; Naoyuki Toyota; Katsuhide Ito; Kazuaki Chayama
Pretreatment predictor of response, time to progression, and survival to intraarterial 5-fluorouracil/interferon combination therapy in patients with advanced hepatocellular carcinoma.
Journal of gastroenterology 2007;42(10):845-53.
2007: Toru Hiyama; Masaharu Yoshihara; Keitaro Matsuo; Hiroaki Kusunoki; Tomoari Kamada; Masanori Ito; Shinji Tanaka; Kazuaki Chayama; Ken Haruma
Treatment of functional dyspepsia with serotonin agonists: a meta-analysis of randomized controlled trials.
Journal of gastroenterology and hepatology 2007;22(10):1566-70.
2007: Kenji Nishioka; Takayuki Hidaka; Shuji Nakamura; Takashi Umemura; Daisuke Jitsuiki; Junko Soga; Chikara Goto; Kazuaki Chayama; Masao Yoshizumi; Yukihito Higashi
Pycnogenol, French maritime pine bark extract, augments endothelium-dependent vasodilation in humans.
Hypertension research : official journal of the Japanese Society of Hypertension 2007;30(9):775-80.
2007: Xue Fei Xie; Masanori Ito; Masaharu Yoshihara; Ken Haruma; Shinji Tanaka; Kazuaki Chayama
Serum pepsinogen levels in the Japanese population: prospective study of 9 years of follow-up.
Hepato-gastroenterology 2007;54(78):1887-90.
2007: Shinichi Mukai; Toru Hiyama; Shinji Tanaka; Masaharu Yoshihara; Koji Arihiro; Kazuaki Chayama
Involvement of Kruppel-like factor 6 (KLF6) mutation in the development of nonpolypoid colorectal carcinoma.
World journal of gastroenterology : WJG 2007;13(29):3932-8.
2007: Nobuhiko Hiraga; Hiroshi Aikata; Shintaro Takaki; Hideaki Kodama; Hiroo Shirakawa; Michio Imamura; Yoshiiku Kawakami; Shoichi Takahashi; Naoyuki Toyota; Katsuhide Ito; Shinji Tanaka; Mikiya Kitamoto; Kazuaki Chayama
The long-term outcome of patients with bleeding gastric varices after balloon-occluded retrograde transvenous obliteration.
Journal of gastroenterology 2007;42(8):663-72.
2007: Chikara Goto; Kenji Nishioka; Takashi Umemura; Daisuke Jitsuiki; Akihiro Sakagutchi; Mitsutoshi Kawamura; Kazuaki Chayama; Masao Yoshizumi; Yukihito Higashi
Acute moderate-intensity exercise induces vasodilation through an increase in nitric oxide bioavailiability in humans.
American journal of hypertension 2007;20(8):825-30.
2007: Akihiro Matsumoto; Eiji Tanaka; Masahito Minami; Takeshi Okanoue; Hiroshi Yatsuhashi; Shinya Nagaoka; Fumitaka Suzuki; Mariko Kobayashi; Kazuaki Chayama; Michio Imamura; Hiroshi Yotsuyanagi; Shigeru Nakaoka; Noboru Maki; Sumio Kawata; Hiromitsu Kumada; Shiro Iino; Kendo Kiyosawa
Low serum level of hepatitis B core-related antigen indicates unlikely reactivation of hepatitis after cessation of lamivudine therapy.
Hepatology research : the official journal of the Japan Society of Hepatology 2007;37(8):661-6.
2007: Iwao Kaneko; Shinji Tanaka; Shiro Oka; Shigeto Yoshida; Toru Hiyama; Koji Arihiro; Fumio Shimamoto; Kazuaki Chayama
Immunohistochemical molecular markers as predictors of curability of endoscopically resected submucosal colorectal cancer.
World journal of gastroenterology : WJG 2007;13(28):3829-35.
2007: Shigeto Yoshida; Shinji Tanaka; Mayuko Hirata; Ritsuo Mouri; Iwao Kaneko; Shiro Oka; Masaharu Yoshihara; Kazuaki Chayama
Optical biopsy of GI lesions by reflectance-type laser-scanning confocal microscopy.
Gastrointestinal endoscopy 2007;66(1):144-9.
2007: Shinji Tanaka; Shiro Oka; Iwao Kaneko; Mayuko Hirata; Ritsuo Mouri; Hiroyuki Kanao; Shigeto Yoshida; Kazuaki Chayama
Endoscopic submucosal dissection for colorectal neoplasia: possibility of standardization.
Gastrointestinal endoscopy 2007;66(1):100-7.
2007: Hideyuki Hyogo; Sho-ichi Yamagishi; Keiko Iwamoto; Koji Arihiro; Masayoshi Takeuchi; Takashi Sato; Hidenori Ochi; Michihiro Nonaka; Yoshitaka Nabeshima; Motoki Inoue; Tomokazu Ishitobi; Kazuaki Chayama; Susumu Tazuma
Elevated levels of serum advanced glycation end products in patients with non-alcoholic steatohepatitis.
Journal of gastroenterology and hepatology 2007;22(7):1112-9.
2007: Yoshihiro Miyanaka; Yoshitaka Ueno; Shinji Tanaka; Kyoko Yoshioka; Tsuyoshi Hatakeyama; Masaru Shimamoto; Masaharu Sumii; Kazuaki Chayama
Clinical significance of mucosal suppressors of cytokine signaling 3 expression in ulcerative colitis.
World journal of gastroenterology : WJG 2007;13(21):2939-44.
2007: Hiroaki Kusunoki; Jiro Hata; Shinya Aoki; Tomoari Kamada; Manabu Ishii; Motonori Sato; Toshiaki Tanaka; Noriaki Manabe; Akiko Shiotani; Shigeto Yoshida; Shinji Tanaka; Kazuaki Chayama; Ken Haruma
Stepped assessment of gastric emptying of a solid meal using the (13)C-octanoic acid breath test.
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 2007;43(3):99-107.
2007: Hirotaka Tashiro; Toshiyuki Itamoto; Hideki Ohdan; Yasuhiro Fudaba; Toshihiko Kohashi; Hironobu Amano; Kohei Ishiyama; Shoichi Takahashi; Hiroshi Aikata; Kazuaki Chayama; Koji Arihiro; Toshimasa Asahara
Should splenectomy be performed for hepatitis C patients undergoing living-donor liver transplantation?
Journal of gastroenterology and hepatology 2007;22(6):959-60.
2007: Masashi Kimura; Keiko Ueda; Chikara Goto; Daisuke Jitsuiki; Kenji Nishioka; Takashi Umemura; Kensuke Noma; Masao Yoshizumi; Kazuaki Chayama; Yukihito Higashi
Repetition of ischemic preconditioning augments endothelium-dependent vasodilation in humans: role of endothelium-derived nitric oxide and endothelial progenitor cells.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(6):1403-10.
2007: Mayuko Hirata; Shinji Tanaka; Shiro Oka; Iwao Kaneko; Shigeto Yoshida; Masaharu Yoshihara; Kazuaki Chayama
Magnifying endoscopy with narrow band imaging for diagnosis of colorectal tumors.
Gastrointestinal endoscopy 2007;65(7):988-95.
2007: Hong Chen; Shoichi Takahashi; Michio Imamura; Eiko Okutani; Zhi-guo Zhang; Kazuaki Chayama; Bao-An Chen
Earthworm fibrinolytic enzyme: anti-tumor activity on human hepatoma cells in vitro and in vivo.
Chinese medical journal 2007;120(10):898-904.
2007: Nobuhiko Hiraga; Michio Imamura; Masataka Tsuge; Chiemi Noguchi; Shoichi Takahashi; Eiji Iwao; Yoshifumi Fujimoto; Hiromi Abe; Toshiro Maekawa; Hidenori Ochi; Chise Tateno; Katsutoshi Yoshizato; Akihito Sakai; Yoshio Sakai; Masao Honda; Shuichi Kaneko; Takaji Wakita; Kazuaki Chayama
Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis C virus and its susceptibility to interferon.
FEBS letters 2007;581(10):1983-7.
2007: Yasuo Egi; Masanori Ito; Shinji Tanaka; Shinobu Imagawa; Shunsuke Takata; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Role of Helicobacter pylori infection and chronic inflammation in gastric cancer in the cardia.
Japanese journal of clinical oncology 2007;37(5):365-9.
2007: Tsuyoshi Hatakeyama; Chiemi Noguchi; Nobuhiko Hiraga; Nami Mori; Masataka Tsuge; Michio Imamura; Shoichi Takahashi; Yoshiiku Kawakami; Yoshifumi Fujimoto; Hidenori Ochi; Hiromi Abe; Toshiro Maekawa; Hiroiku Kawakami; Hiromi Yatsuji; Yasuyuki Aisaka; Hiroshi Kohno; Shiomi Aimitsu; Kazuaki Chayama
Serum HBV RNA is a predictor of early emergence of the YMDD mutant in patients treated with lamivudine.
Hepatology (Baltimore, Md.) 2007;45(5):1179-86.
2007: Junko Soga; Kenji Nishioka; Shuji Nakamura; Takashi Umemura; Daisuke Jitsuiki; Takayuki Hidaka; Hiroki Teragawa; Hiroaki Takemoto; Chikara Goto; Masao Yoshizumi; Kazuaki Chayama; Yukihito Higashi
Measurement of flow-mediated vasodilation of the brachial artery: a comparison of measurements in the seated and supine positions.
Circulation journal : official journal of the Japanese Circulation Society 2007;71(5):736-40.
2007: Kayoko Kunihiro; Jiro Hata; Noriaki Manabe; Yutaka Mitsuoka; Shinji Tanaka; Ken Haruma; Kazuaki Chayama
Predicting the need for surgery in Crohn's disease with contrast harmonic ultrasound.
Scandinavian journal of gastroenterology 2007;42(5):577-85.
2007: Andrei Brydun; Yuichiro Watari; Yoshiyuki Yamamoto; Koichiro Okuhara; Hiroki Teragawa; Fujiko Kono; Kazuaki Chayama; Tetsuya Oshima; Ryoji Ozono
Reduced expression of heme oxygenase-1 in patients with coronary atherosclerosis.
Hypertension research : official journal of the Japanese Society of Hypertension 2007;30(4):341-8.
2007: Yutaka Mitsuoka; Jiro Hata; Ken Haruma; Noriaki Manabe; Shinji Tanaka; Kazuaki Chayama
New method of evaluating gastric mucosal blood flow by ultrasound.
Scandinavian journal of gastroenterology 2007;42(4):513-8.
2007: Masanori Miyazaki; Yukihito Higashi; Chikara Goto; Kazuaki Chayama; Masao Yoshizumi; Hiroaki Sanada; Kazumasa Orihashi; Taijiro Sueda
Sarpogrelate hydrochloride, a selective 5-HT2A antagonist, improves vascular function in patients with peripheral arterial disease.
Journal of cardiovascular pharmacology 2007;49(4):221-7.
2007: Shunsuke Takata; Masanori Ito; Masaharu Yoshihara; Shinji Tanaka; Shinobu Imagawa; Ken Haruma; Kazuaki Chayama
Host factors contributing to the discovery of gastric cancer after successful eradication therapy of Helicobacter pylori: preliminary report.
Journal of gastroenterology and hepatology 2007;22(4):571-6.
2007: Akira Fukumoto; Noriaki Manabe; Shinji Tanaka; Toshiki Yamaguchi; Yoshiaki Matsumoto; Kazuaki Chayama
Usefulness of EUS with double-balloon enteroscopy for diagnosis of small-bowel diseases.
Gastrointestinal endoscopy 2007;65(3):412-20.
2007: Toru Hiyama; Masaharu Yoshihara; Keitaro Matsuo; Hiroaki Kusunoki; Tomoari Kamada; Masanori Ito; Shinji Tanaka; Nobuo Nishi; Kazuaki Chayama; Ken Haruma
Meta-analysis of the effects of prokinetic agents in patients with functional dyspepsia.
Journal of gastroenterology and hepatology 2007;22(3):304-10.
2007: Kensuke Noma; Chikara Goto; Kenji Nishioka; Daisuke Jitsuiki; Takashi Umemura; Keiko Ueda; Masashi Kimura; Keigo Nakagawa; Tetsuya Oshima; Kazuaki Chayama; Masao Yoshizumi; James K Liao; Yukihito Higashi
Roles of rho-associated kinase and oxidative stress in the pathogenesis of aortic stiffness.
Journal of the American College of Cardiology 2007;49(6):698-705.
2007: Shinji Tanaka; Shiro Oka; Kazuaki Chayama
[Application of colonoscopy for patients with colonic adenoma--evaluation of the treatment efficacy and follow-up study].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2007;96(2):271-6.
2007: Shigeru Kimura; Shinji Tanaka; Hiroaki Kusunoki; Yasuhiko Kitadai; Masaharu Sumii; Susumu Tazuma; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Cavernous hemangioma in the ascending colon treated by endoscopic mucosal resection.
Journal of gastroenterology and hepatology 2007;22(2):280-1.
2007: Chiemi Noguchi; Nobuhiko Hiraga; Nami Mori; Masataka Tsuge; Michio Imamura; Shoichi Takahashi; Yoshifumi Fujimoto; Hidenori Ochi; Hiromi Abe; Toshiro Maekawa; Hiromi Yatsuji; Kotaro Shirakawa; Akifumi Takaori-Kondo; Kazuaki Chayama
Dual effect of APOBEC3G on Hepatitis B virus.
The Journal of general virology 2007;88(Pt 2):432-40.
2007: Michiyo Kodama; Yasuhiko Kitadai; Masanori Ito; Hirohisa Kai; Hiroshi Masuda; Shinji Tanaka; Masaharu Yoshihara; Kingo Fujimura; Kazuaki Chayama
Immune response to CagA protein is associated with improved platelet count after Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura.
Helicobacter 2007;12(1):36-42.
2007: Kenji Nishioka; Keigo Nakagawa; Takashi Umemura; Daisuke Jitsuiki; Keiko Ueda; Chikara Goto; Kazuaki Chayama; Masao Yoshizumi; Yukihito Higashi
Carvedilol improves endothelium-dependent vasodilation in patients with dilated cardiomyopathy.
Heart (British Cardiac Society) 2007;93(2):247-8.
2007: Kiminori Uka; Hiroshi Aikata; Shintaro Takaki; Hiroo Shirakawa; Soo Cheol Jeong; Keitaro Yamashina; Akira Hiramatsu; Hideaki Kodama; Shoichi Takahashi; Kazuaki Chayama
Clinical features and prognosis of patients with extrahepatic metastases from hepatocellular carcinoma.
World journal of gastroenterology : WJG 2007;13(3):414-20.
2007: Shintaro Takaki; Yoshiiku Kawakami; Michio Imamura; Hiroshi Aikata; Shoichi Takahashi; Hiroto Ishihara; Keiji Tsuji; Shiomi Aimitsu; Hiroiku Kawakami; Toshio Nakanishi; Mikiya Kitamoto; Takashi Moriya; Kenichi Satoh; Kazuaki Chayama
Eicosapentaenoic acid could permit maintenance of the original ribavirin dose in chronic hepatitis C virus patients during the first 12 weeks of combination therapy with pegylated interferon-alpha and ribavirin. A prospective randomized controlled trial.
Intervirology 2007;50(6):439-46.
2007: Hideaki Kodama; Hiroshi Aikata; Kiminori Uka; Shintaro Takaki; Nami Mori; Koji Waki; Soo Cheol Jeong; Yoshiiku Kawakami; Hiroo Shirakawa; Shoichi Takahashi; Naoyuki Toyota; Katsuhide Ito; Kazuaki Chayama
Efficacy of percutaneous cementoplasty for bone metastasis from hepatocellular carcinoma.
Oncology 2007;72(5-6):285-92.
2007: Xue Fei Xie; Masanori Ito; Masaharu Sumii; Shinji Tanaka; Masaharu Yoshihara; Kazuaki Chayama
Helicobacter pylori-associated gastritis is related to babA2 expression without heterogeneity of the 3' region of the cagA genotype in gastric biopsy specimens.
Pathobiology : journal of immunopathology, molecular and cellular biology 2007;74(5):309-16.
2007: Yoshio Katamura; Hiroshi Aikata; Takahiro Azakami; Tomokazu Kawaoka; Kiminori Uka; Keitaro Yamashina; Shintaro Takaki; Hideaki Kodama; Jeong Soo Cheol; Akira Hiramatsu; Michio Imamura; Yoshiiku Kawakami; Shoichi Takahashi; Naoyuki Toyota; Katsuhide Ito; Kazuaki Chayama
Balloon-occluded retrograde transvenous obliteration for portal-systemic encephalopathy due to superior mesenteric-caval shunt via the right gonadal vein.
Internal medicine (Tokyo, Japan) 2007;46(17):1479-80.
2007: Miwa Miyoshi; Yukiko Nakano; Takemasa Sakaguchi; Hiroshi Ogi; Noboru Oda; Kazuyoshi Suenari; Katsuhiro Kiyotani; Ryoji Ozono; Tetsuya Oshima; Tetsuya Yoshida; Kazuaki Chayama
Gene delivery of paraoxonase-1 inhibits neointimal hyperplasia after arterial balloon-injury in rabbits fed a high-fat diet.
Hypertension research : official journal of the Japanese Society of Hypertension 2007;30(1):85-91.
2007: Yukiko Nakano; Satoshi Tashiro; Eiji Kinoshita; Emiko Kinoshita-Kikuta; Sou Takenaka; Miwa Miyoshi; Hiroshi Ogi; Eiichiro Sakoda; Noboru Oda; Kazuyoshi Suenari; Yukiji Tonouchi; Tomokazu Okimoto; Yukoh Hirai; Fumiharu Miura; Kazuko Yamaoka; Tohru Koike; Kazuaki Chayama
Non-SCN5A related Brugada syndromes: verification of normal splicing and trafficking of SCN5A without exonic mutations.
Annals of human genetics 2007;71(Pt 1):8-17.
2007: Akira Tari; Yasuhiko Kitadai; Masaharu Sumii; Atsunori Sasaki; Hiroshi Tani; Sinji Tanaka; Kazuaki Chayama
Basis of decreased risk of gastric cancer in severe atrophic gastritis with eradication of Helicobacter pylori.
Digestive diseases and sciences 2007;52(1):232-9.
2007: Iwao Kaneko; Shinji Tanaka; Shiro Oka; Toru Kawamura; Toru Hiyama; Masanori Ito; Masaharu Yoshihara; Fumio Shimamoto; Kazuaki Chayama
Lymphatic vessel density at the site of deepest penetration as a predictor of lymph node metastasis in submucosal colorectal cancer.
Diseases of the colon and rectum 2007;50(1):13-21.
2006: Toru Hiyama; Masaharu Yoshihara; Shinji Tanaka; Yuji Urabe; Yoshihiko Ikegami; Tatsuma Fukuhara; Kazuaki Chayama
Defensive medicine practices among gastroenterologists in Japan.
World journal of gastroenterology : WJG 2006;12(47):7671-5.
2006: Shiro Oka; Shinji Tanaka; Iwao Kaneko; Ritsuo Mouri; Mayuko Hirata; Toru Kawamura; Masaharu Yoshihara; Kazuaki Chayama
Advantage of endoscopic submucosal dissection compared with EMR for early gastric cancer.
Gastrointestinal endoscopy 2006;64(6):877-83.
2006: Takashi Umemura; Keiko Ueda; Kenji Nishioka; Takayuki Hidaka; Hiroaki Takemoto; Shuji Nakamura; Daisuke Jitsuiki; Junko Soga; Chikara Goto; Kazuaki Chayama; Masao Yoshizumi; Yukihito Higashi
Effects of acute administration of caffeine on vascular function.
The American journal of cardiology 2006;98(11):1538-41.
2006: Y Matsumoto; Noriaki Manabe; Shinji Tanaka; Akira Fukumoto; Toshiki Yamaguchi; Masaru Shimamoto; Madoka Nakao; Yutaka Mitsuoka; Kazuaki Chayama
Small-intestinal Peutz-Jeghers polyps resected by endoscopic polypectomy with double-balloon enteroscopy and removal confirmed by ultrasonography.
Digestive diseases and sciences 2006;51(12):2337-40.
2006: Songde Cho; Yasuhiko Kitadai; Shigeto Yoshida; Shinji Tanaka; Masaharu Yoshihara; Kazuhiro Yoshida; Kazuaki Chayama
Genetic and pathologic characteristics of gastrointestinal stromal tumors in extragastric lesions.
International journal of molecular medicine 2006;18(6):1067-71.
2006: Waka Ohishi; Saeko Fujiwara; Gen Suzuki; Takeshi Kishi; Misae Sora; Shinsuke Matsuura; Masayuki Hakoda; Yoshimi Tatsukawa; Michiko Yamada; Kazuaki Chayama
Feasibility of freeze-dried sera for serological and molecular biological detection of hepatitis B and C viruses.
Journal of clinical microbiology 2006;44(12):4593-5.
2006: Toru Hiyama; Shinji Tanaka; Masaharu Yoshihara; Tatsuma Fukuhara; Shinichi Mukai; Kazuaki Chayama
Medical malpractice litigation related to gastrointestinal endoscopy in Japan: a two-decade review of civil court cases.
World journal of gastroenterology : WJG 2006;12(42):6857-60.
2006: Hideki Miyata; Kenichi Kuwahara; Shinichirou Sugiyama; Tomohiro Iiboshi; Masahiro Serikawa; Kensou Kobayashi; Bunjirou Noma; Masahide Iwasa; Hiroshi Itsuki; Tamito Sasaki; Yoshiaki Murakami; Kazuaki Chayama
[A case of pancreatic solid-pseudopapillary tumor without cystic component in an elderly man].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2006;103(11):1288-95.
2006: Hiromi Yatsuji; Chiemi Noguchi; Nobuhiko Hiraga; Nami Mori; Masataka Tsuge; Michio Imamura; Shoichi Takahashi; Eiji Iwao; Yoshifumi Fujimoto; Hidenori Ochi; Hiromi Abe; Toshiro Maekawa; Chise Tateno; Katsutoshi Yoshizato; Fumitaka Suzuki; Hiromitsu Kumada; Kazuaki Chayama
Emergence of a novel lamivudine-resistant hepatitis B virus variant with a substitution outside the YMDD motif.
Antimicrobial agents and chemotherapy 2006;50(11):3867-74.
2006: Shiro Oka; Shinji Tanaka; Iwao Kaneko; Ritsuo Mouri; Mayuko Hirata; Hiroyuki Kanao; Toru Kawamura; Shigeto Yoshida; Masaharu Yoshihara; Kazuaki Chayama
Endoscopic submucosal dissection for residual/local recurrence of early gastric cancer after endoscopic mucosal resection.
Endoscopy 2006;38(10):996-1000.
2006: Masahiro Serikawa; Tamito Sasaki; Yoshifumi Fujimoto; Kenichi Kuwahara; Kazuaki Chayama
Management of intraductal papillary-mucinous neoplasm of the pancreas: treatment strategy based on morphologic classification.
Journal of clinical gastroenterology 2006;40(9):856-62.
2006: Takashi Umemura; Kenji Nishioka; Akira Igarashi; Yukio Kato; Mitsuo Ochi; Kazuaki Chayama; Masao Yoshizumi; Yukihito Higashi
Autologous bone marrow mononuclear cell implantation induces angiogenesis and bone regeneration in a patient with compartment syndrome.
Circulation journal : official journal of the Japanese Circulation Society 2006;70(10):1362-4.
2006: Shinji Tanaka; Tonya Kaltenbach; Kazuaki Chayama; Roy Soetikno
High-magnification colonoscopy (with videos).
Gastrointestinal endoscopy 2006;64(4):604-13.
2006: Hideyuki Shima; Toru Hiyama; Shinji Tanaka; Masaharu Yoshihara; Koji Arihiro; Kazuaki Chayama
Genetic progression and divergence in superficial esophageal squamous cell carcinoma by loss of heterozygosity analysis.
Oncology reports 2006;16(4):685-91.
2006: Akira Hiramatsu; Bin Gotoh; Yutaka Fujii; Tetsuya Yoshida; Kazuaki Chayama; Takemasa Sakaguchi
Suppression of interferon-related promoter activation by hepatitis C virus proteins expressed in cultured cells.
Hiroshima journal of medical sciences 2006;55(3):71-7.
2006: Shogo Sasao; Toru Hiyama; Shinji Tanaka; Shinichi Mukai; Masaharu Yoshihara; Kazuaki Chayama
Medical malpractice litigation in gastroenterological practice in Japan: a 22-yr review of civil court cases.
The American journal of gastroenterology 2006;101(9):1951-3.
2006: Toshiya Kobuke; Susumu Tazuma; Hideyuki Hyogo; Kazuaki Chayama
A Ligand for peroxisome proliferator-activated receptor gamma inhibits human cholangiocarcinoma cell growth: potential molecular targeting strategy for cholangioma.
Digestive diseases and sciences 2006;51(9):1650-7.
2006: Yoshitaka Ueno; Shinji Tanaka; Hiroyuki Kanao; Kyoko Yoshioka; Tsuyoshi Hatakeyama; Masaru Shimamoto; Yoshihiro Miyanaka; Toru Hiyama; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Kazuaki Chayama
A case of Crohn's disease with hydronephrosis caused by ureteropelvic junction obstruction.
European journal of gastroenterology & hepatology 2006;18(9):1015-8.
2006: Yasuo Egi; Sunjin Kim; Masanori Ito; Shinji Tanaka; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Helicobacter pylori infection is the major risk factor for gastric inflammation in the cardia.
Digestive diseases and sciences 2006;51(9):1582-8.
2006: Yoshitaka Nabeshima; Susumu Tazuma; Keishi Kanno; Hideyuki Hyogo; Masaru Iwai; Masatsugu Horiuchi; Kazuaki Chayama
Anti-fibrogenic function of angiotensin II type 2 receptor in CCl4-induced liver fibrosis.
Biochemical and biophysical research communications 2006;346(3):658-64.
2006: Takuya Umehara; masayuki sudoh; Fumihiko Yasui; Chiho Matsuda; Yukiko Hayashi; Kazuaki Chayama; Michinori Kohara
Serine palmitoyltransferase inhibitor suppresses HCV replication in a mouse model.
Biochemical and biophysical research communications 2006;346(1):67-73.
2006: Kayoko Kunihiro; Noriaki Manabe; Jiro Hata; Daisuke Kamino; Madoka Nakao; Yutaka Mitsuoka; Shinji Tanaka; Kazuaki Chayama
Gastrointestinal stromal tumor in jejunum: diagnosis using contrast-enhanced ultrasonography and double-balloon enteroscopy.
Digestive diseases and sciences 2006;51(7):1236-40.
2006: Michio Imamura; Kazuaki Chayama
[HCV-HBV infection].
Nihon rinsho. Japanese journal of clinical medicine 2006;64(7):1310-3.
2006: Noriaki Manabe; Shinji Tanaka; Akira Fukumoto; Madoka Nakao; Daisuke Kamino; Kazuaki Chayama
Double-balloon enteroscopy in patients with GI bleeding of obscure origin.
Gastrointestinal endoscopy 2006;64(1):135-40.
2006: Shogo Sasao; Toru Hiyama; Shinji Tanaka; Masaharu Yoshihara; Wataru Yasui; Kazuaki Chayama
Clinicopathologic and genetic characteristics of gastric cancer in young male and female patients.
Oncology reports 2006;16(1):11-5.
2006: Daisuke Kamino; Jiro Hata; Ken Haruma; Noriaki Manabe; Shinji Tanaka; Kazuaki Chayama
Real-time visualization and quantitation of canine gastric mucosal blood flow by contrast-enhanced ultrasonography.
Scandinavian journal of gastroenterology 2006;41(7):856-61.
2006: Takehiko Ochiumi; Yasuhiko Kitadai; Shinji Tanaka; Morihisa Akagi; Masaharu Yoshihara; Kazuaki Chayama
Neuropilin-1 is involved in regulation of apoptosis and migration of human colon cancer.
International journal of oncology 2006;29(1):105-16.
2006: Haruna Yokomichi; Keiji Tsuji; Yuzo Hayashi; Mayumi Kaneko; Koichi Nakadoi; Yuki Ishida; Takayasu Kuwabara; Takako Tsumuna; Tomonori Sumida; Shinji Nagata; Hiroaki Ohgoshi; Sanshiro Uraki; Tohru Hidaka; Kazuaki Chayama
A case of multiple hepatic peribiliary cysts which contributed to the obstructive jaundice and led to liver failure at the young man with von Recklinghausen's disease.
Hepatology research : the official journal of the Japan Society of Hepatology 2006;35(3):222-7.
2006: Songde Cho; Yasuhiko Kitadai; Shigeto Yoshida; Shinji Tanaka; Masaharu Yoshihara; Kazuhiro Yoshida; Kazuaki Chayama
Deletion of the KIT gene is associated with liver metastasis and poor prognosis in patients with gastrointestinal stromal tumor in the stomach.
International journal of oncology 2006;28(6):1361-7.
2006: Yukihito Higashi; Shota Sasaki; Keigo Nakagawa; Masashi Kimura; Kensuke Noma; Keiko Hara; Daisuke Jitsuiki; Chikara Goto; Tetsuya Oshima; Kazuaki Chayama; Masao Yoshizumi
Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production.
Atherosclerosis 2006;186(2):390-5.
2006: Sunjin Kim; Masanori Ito; Ken Haruma; Yasuo Egi; Hiroyuki Ueda; Shinji Tanaka; Kazuaki Chayama
Surface structure of antral gastric mucosa represents the status of histologic gastritis: fundamental evidence for the evaluation of antral gastritis by magnifying endoscopy.
Journal of gastroenterology and hepatology 2006;21(5):837-41.
2006: T Yamaguchi; Noriaki Manabe; Jiro Hata; Shinji Tanaka; Ken Haruma; Kazuaki Chayama
The usefulness of transabdominal ultrasound for the diagnosis of lower gastrointestinal bleeding.
Alimentary pharmacology & therapeutics 2006;23(8):1267-72.
2006: Yukihito Higashi; Kenji Nishioka; Takashi Umemura; Kazuaki Chayama; Masao Yoshizumi
Oxidative stress, endothelial function and angiogenesis induced by cell therapy and gene therapy.
Current pharmaceutical biotechnology 2006;7(2):109-16.
2006: Hiroyuki Ueda; Masanori Ito; Shinji Tanaka; Shiro Oka; Shunsuke Takata; Shinobu Imagawa; Xue Fei Xie; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
The effect of Helicobacter pylori eradication therapy on gastric ulcer healing after endoscopic mucosal resection.
Journal of clinical gastroenterology 2006;40(4):293-6.
2006: Hideki Miyata; Tamito Sasaki; Kenichi Kuwahara; Masahiro Serikawa; Kazuaki Chayama
The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines.
International journal of oncology 2006;28(4):915-21.
2006: Shinji Tanaka; Ken Haruma; Masaharu Yoshihara; Goro Kajiyama; Kazuya Kira; Harunobu Amagase; Kazuaki Chayama
Aged garlic extract has potential suppressive effect on colorectal adenomas in humans.
The Journal of nutrition 2006;136(3 Suppl):821S-826S.
2006: Roy Soetikno; Shai Friedland; Tonya Kaltenbach; Kazuaki Chayama; Shinji Tanaka
Nonpolypoid (flat and depressed) colorectal neoplasms.
Gastroenterology 2006;130(2):566-76; quiz 588-9.
2006: Keitaro Yamashina; Hideki Yamamoto; Kazuaki Chayama; Koichi Nakajima; Akira Kikuchi
Suppression of STAT3 activity by Duplin, which is a negative regulator of the Wnt signal.
Journal of biochemistry 2006;139(2):305-14.
2006: Eiji Tanaka; Akihiro Matsumoto; Fumitaka Suzuki; Mariko Kobayashi; Masashi Mizokami; Yasuhito Tanaka; Takeshi Okanoue; Masahito Minami; Kazuaki Chayama; Michio Imamura; Hiroshi Yatsuhashi; Shinya Nagaoka; Hiroshi Yotsuyanagi; Sumio Kawata; Tatsuji Kimura; Noboru Maki; Shiro Iino; Kendo Kiyosawa
Measurement of hepatitis B virus core-related antigen is valuable for identifying patients who are at low risk of lamivudine resistance.
Liver international : official journal of the International Association for the Study of the Liver 2006;26(1):90-6.
2006: Masanori Ito; Shinji Tanaka; Tomoari Kamada; Ken Haruma; Kazuaki Chayama
Causal role of Helicobacter pylori infection and eradication therapy in gastric carcinogenesis.
World journal of gastroenterology : WJG 2006;12(1):10-6.
2006: Yukihito Higashi; Daisuke Jitsuiki; Kazuaki Chayama; Masao Yoshizumi
Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for treatment of cardiovascular diseases.
Recent patents on cardiovascular drug discovery 2006;1(1):85-93.
2006: Lan Ni; Hiroki Teragawa; Kentaro Ueda; Hiroaki Takemoto; Takayuki Hidaka; Kenji Nishioka; Junko Soga; Noboru Oda; Yukiko Nakano; Tetsuji Shingu; Kazuaki Chayama
Successive, rapid recurrences of in-stent restenoses in a woman with angina pectoris.
Internal medicine (Tokyo, Japan) 2006;45(19):1093-6.
2006: Kazuhiro Kose; Toru Hiyama; Shinji Tanaka; Masaharu Yoshihara; Wataru Yasui; Kazuaki Chayama
Nuclear and mitochondrial DNA microsatellite instability in gastrointestinal stromal tumors.
Pathobiology : journal of immunopathology, molecular and cellular biology 2006;73(2):93-7.
2006: Hiroshi Kohno; Shiomi Aimitsu; Mikiya Kitamoto; Yasuyuki Aisaka; Hiroiku Kawakami; Kazuaki Chayama
Prolonged negative HCV-RNA status led to a good outcome in chronic hepatitis C patients with genotype 1b and super-high viral load.
Intervirology 2006;49(6):362-9.
2006: Keiko Arataki; Hiromitsu Kumada; Kiyomi Toyota; Waka Ohishi; Shoichi Takahashi; Susumu Tazuma; Kazuaki Chayama
Evolution of hepatitis C virus quasispecies during ribavirin and interferon-alpha-2b combination therapy and interferon-alpha-2b monotherapy.
Intervirology 2006;49(6):352-61.
2006: Hiroyuki Ueda; Masanori Ito; Hidetaka Eguchi; Shinji Tanaka; Masaharu Yoshihara; Ken Haruma; Masanori Hatakeyama; Kazuaki Chayama
Development of a novel method to detect Helicobacter pylori cagA genotype from paraffin-embedded materials: comparison between patients with duodenal ulcer and gastric cancer in young Japanese.
Digestion 2006;73(1):47-53.
2006: Tomoari Kamada; Kuniaki Sugiu; Jiro Hata; Hiroaki Kusunoki; Hiroshige Hamada; Soichiro Kido; Yuichi Nagashima; Yuzuru Kawamura; Shinji Tanaka; Kazuaki Chayama; Ken Haruma
Evaluation of endoscopic and histological findings in Helicobacter pylori-positive Japanese young adults.
Journal of gastroenterology and hepatology 2006;21(1 Pt 2):258-61.
2006: Bunjirou Noma; Tamito Sasaki; Masahiro Serikawa; Kenichi Kuwahara; Kazuaki Chayama
[Management of diagnosis for biliary tract cancer].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 1():426-30.
2005: Masayuki Katsumoto; Tetsuji Shingu; Rieko Kuwashima; Atsunori Nakata; Shuichi Nomura; Kazuaki Chayama
Biphasic effect of HMG-CoA reductase inhibitor, pitavastatin, on vascular endothelial cells and angiogenesis.
Circulation journal : official journal of the Japanese Circulation Society 2005;69(12):1547-55.
2005: Daisuke Komichi; Susumu Tazuma; Tomoji Nishioka; Hideyuki Hyogo; Kazuaki Chayama
Glycochenodeoxycholate plays a carcinogenic role in immortalized mouse cholangiocytes via oxidative DNA damage.
Free radical biology & medicine 2005;39(11):1418-27.
2005: Kensuke Noma; Chikara Goto; Kenji Nishioka; Keiko Hara; Masashi Kimura; Takashi Umemura; Daisuke Jitsuiki; Keigo Nakagawa; Tetsuya Oshima; Kazuaki Chayama; Masao Yoshizumi; Yukihito Higashi
Smoking, endothelial function, and Rho-kinase in humans.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(12):2630-5.
2005: Tsuyoshi Kuroda; Yasuhiko Kitadai; Shinji Tanaka; Xiaoqin Yang; Naofumi Mukaida; Masaharu Yoshihara; Kazuaki Chayama
Monocyte chemoattractant protein-1 transfection induces angiogenesis and tumorigenesis of gastric carcinoma in nude mice via macrophage recruitment.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(21):7629-36.
2005: Masataka Tsuge; Nobuhiko Hiraga; Hideki Takaishi; Chiemi Noguchi; Hiromi Oga; Michio Imamura; Shoichi Takahashi; Eiji Iwao; Yoshifumi Fujimoto; Hidenori Ochi; Kazuaki Chayama; Chise Tateno; Katsutoshi Yoshizato
Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus.
Hepatology (Baltimore, Md.) 2005;42(5):1046-54.
2005: Kazuhiro Kose; Toru Hiyama; Shinji Tanaka; Masaharu Yoshihara; Wataru Yasui; Kazuaki Chayama
Somatic mutations of mitochondrial DNA in digestive tract cancers.
Journal of gastroenterology and hepatology 2005;20(11):1679-84.
2005: Eiji Kinoshita; Emiko Kinoshita-Kikuta; Hirokazu Kojima; Yukiko Nakano; Kazuaki Chayama; Tohru Koike
Reliable and cost-effective screening of inherited heterozygosity by Zn2+-cyclen polyacrylamide gel electrophoresis.
Clinical chemistry 2005;51(11):2195-8.
2005: Narimasa Miho; Takafumi Ishida; Noriko Kuwaba; Mari Ishida; Keiko Shimote-Abe; Kumiko Tabuchi; Tetsuya Oshima; Masao Yoshizumi; Kazuaki Chayama
Role of the JNK pathway in thrombin-induced ICAM-1 expression in endothelial cells.
Cardiovascular research 2005;68(2):289-98.
2005: Hiroki Teragawa; Kentaro Ueda; Keiji Matsuda; Masashi Kimura; Yukihito Higashi; Tetsuya Oshima; Masao Yoshizumi; Kazuaki Chayama
Relationship between endothelial function in the coronary and brachial arteries.
Clinical cardiology 2005;28(10):460-6.
2005: Yoshihiro Numata; Susumu Tazuma; Yoshitaka Ueno; Tomoji Nishioka; Hideyuki Hyogo; Kazuaki Chayama
Therapeutic effect of repeated natural killer T cell stimulation in mouse cholangitis complicated by colitis.
Digestive diseases and sciences 2005;50(10):1844-51.
2005: Kentaro Ueda; Hiroki Teragawa; Masashi Kimura; Keiji Matsuda; Yukihito Higashi; Togo Yamagata; Tetsuya Oshima; Masao Yoshizumi; Kazuaki Chayama
Adrenomedullin causes coronary vasodilation in humans: effects of inhibition of nitric oxide synthesis.
Journal of cardiovascular pharmacology 2005;46(4):534-9.
2005: Masataka Tsuge; Ryuji Hamamoto; Fábio Pittella Silva; Yozo Ohnishi; Kazuaki Chayama; Naoyuki Kamatani; Yoichi Furukawa; Yusuke Nakamura
A variable number of tandem repeats polymorphism in an E2F-1 binding element in the 5' flanking region of SMYD3 is a risk factor for human cancers.
Nature genetics 2005;37(10):1104-7.
2005: Shinji Nagata; Shinji Tanaka; Masanori Ito; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Cardiac glands hyperplastic polyp of the stomach.
Journal of gastroenterology and hepatology 2005;20(9):1461-3.
2005: S Yoshida; Shinji Tanaka; Kayoko Kunihiro; Yutaka Mitsuoka; M Hara; Y Kitadai; Jiro Hata; M Yoshihara; Ken Haruma; N Hayakawa; Kazuaki Chayama
Diagnostic ability of high-frequency ultrasound probe sonography in staging early gastric cancer, especially for submucosal invasion.
Abdominal imaging 2005;30(5):518-23.
2005: Seiji Onogawa; Yasuhiko Kitadai; Toru Amioka; Michiyo Kodama; Songde Cho; Tsuyoshi Kuroda; Takehiko Ochiumi; Shigeru Kimura; Toshio Kuwai; Shinji Tanaka; Kazuaki Chayama
Expression of vascular endothelial growth factor (VEGF)-C and VEGF-D in early gastric carcinoma: correlation with clinicopathological parameters.
Cancer letters 2005;226(1):85-90.
2005: Masanori Ito; Shinji Tanaka; Sunjin Kim; Kazumasa Tahara; Yuzuru Kawamura; Masaharu Sumii; Yoshihiko Takehara; Kozo Hayashi; Eiichi Okamoto; Masaki Kunihiro; Toshiro Kunita; Shinobu Imagawa; Shunsuke Takata; Hiroyuki Ueda; Yasuo Egi; Toru Hiyama; Yoshitaka Ueno; Yasuhiko Kitadai; Masaharu Yoshihara; Kazuaki Chayama
A combination of the Helicobacter pylori stool antigen test and urea breath test is useful for clinical evaluation of eradication therapy: a multicenter study.
Journal of gastroenterology and hepatology 2005;20(8):1241-5.
2005: Shoichi Takahashi; Kazuaki Chayama
Integration of hepatitis B virus DNA and hepatocellular carcinoma.
Journal of gastroenterology and hepatology 2005;20(8):1141-2.
2005: Toshiki Yamaguchi; Noriaki Manabe; Shinji Tanaka; Akira Fukumoto; Masaru Shimamoto; Madoka Nakao; Daisuke Kamino; Kazuaki Chayama
Multiple carcinoid tumors of the ileum preoperatively diagnosed by enteroscopy with the double-balloon technique.
Gastrointestinal endoscopy 2005;62(2):315-8.
2005: Atsushi Yamaguchi; Susumu Tazuma; Tomoji Nishioka; Waka Ohishi; Hideyuki Hyogo; Shuichi Nomura; Kazuaki Chayama
Hepatitis C virus core protein modulates fatty acid metabolism and thereby causes lipid accumulation in the liver.
Digestive diseases and sciences 2005;50(7):1361-71.
2005: Yasuhiko Kitadai; Michiyo Kodama; Songde Cho; Tsuyoshi Kuroda; Takehiko Ochiumi; Shigeru Kimura; Shinji Tanaka; Shunji Matsumura; Wataru Yasui; Kazuaki Chayama
Quantitative analysis of lymphangiogenic markers for predicting metastasis of human gastric carcinoma to lymph nodes.
International journal of cancer. Journal international du cancer 2005;115(3):388-92.
2005: Tomoari Kamada; Jiro Hata; Hiroaki Kusunoki; Kuniaki Sugiu; Masanori Ito; Shinji Tanaka; Yuzuru Kawamura; Kazuaki Chayama; Ken Haruma
Effect of long-term half-dose famotidine therapy on corpus gastritis in peptic ulcer disease.
Alimentary pharmacology & therapeutics 2005;21 Suppl 2():99-104.
2005: Tomoari Kamada; Jiro Hata; Hiroaki Kusunoki; Soichiro Kido; H Hamada; R Aoki; T Nishida; K Komoto; H Todo; M Sumioka; T Tanimoto; E Sanuki; Koji Sumii; H Ogoshi; T Hidaka; Q Dongmei; Kazuaki Chayama; Ken Haruma
Effect of famotidine on recurrent bleeding after successful endoscopic treatment of bleeding peptic ulcer.
Alimentary pharmacology & therapeutics 2005;21 Suppl 2():73-8.
2005: Keishi Kanno; Susumu Tazuma; Tomoji Nishioka; Hideyuki Hyogo; Kazuaki Chayama
Angiotensin II participates in hepatic inflammation and fibrosis through MCP-1 expression.
Digestive diseases and sciences 2005;50(5):942-8.
2005: Tomoari Kamada; Jiro Hata; Kuniaki Sugiu; Hiroaki Kusunoki; Masanori Ito; Shinji Tanaka; K Inoue; Yuzuru Kawamura; Kazuaki Chayama; Ken Haruma
Clinical features of gastric cancer discovered after successful eradication of Helicobacter pylori: results from a 9-year prospective follow-up study in Japan.
Alimentary pharmacology & therapeutics 2005;21(9):1121-6.
2005: Yukihito Higashi; Kazuaki Chayama; Masao Yoshizumi
Angiotensin II type I receptor blocker and endothelial function in humans: role of nitric oxide and oxidative stress.
Current medicinal chemistry. Cardiovascular and hematological agents 2005;3(2):133-48.
2005: Keiko Ueda; Chikara Goto; Daisuke Jitsuiki; Takashi Umemura; Kenji Nishioka; Masashi Kimura; Kensuke Noma; Keigo Nakagawa; Tetsuya Oshima; Masao Yoshizumi; Kazuaki Chayama; Yukihito Higashi
The nicorandil-induced vasodilation in humans is inhibited by miconazole.
Journal of cardiovascular pharmacology 2005;45(4):290-4.
2005: Hirohisa Kai; Yasuhiko Kitadai; Michiyo Kodama; Songde Cho; Tsuyoshi Kuroda; Masanori Ito; Shinji Tanaka; Yasukazu Ohmoto; Kazuaki Chayama
Involvement of proinflammatory cytokines IL-1beta and IL-6 in progression of human gastric carcinoma.
Anticancer research 2005;25(2A):709-13.
2005: Daisuke Komichi; Susumu Tazuma; Tomoji Nishioka; Hideyuki Hyogo; Kazuaki Chayama
A nuclear receptor ligand down-regulates cytosolic phospholipase A2 expression to reduce bile acid-induced cyclooxygenase 2 activity in cholangiocytes: implications of anticarcinogenic action of farnesoid X receptor agonists.
Digestive diseases and sciences 2005;50(3):514-24.
2005: Shinichiro Sugiyama; Shosei Kishida; Kazuaki Chayama; Shinya Koyama; Akira Kikuchi
Ubiquitin-interacting motifs of Epsin are involved in the regulation of insulin-dependent endocytosis.
Journal of biochemistry 2005;137(3):355-64.
2005: Masanori Ito; Shinji Tanaka; Shunsuke Takata; Shiro Oka; Shinobu Imagawa; Hiroyuki Ueda; Yasuo Egi; Yasuhiko Kitadai; W Yasui; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Morphological changes in human gastric tumours after eradication therapy of Helicobacter pylori in a short-term follow-up.
Alimentary pharmacology & therapeutics 2005;21(5):559-66.
2005: Chiemi Noguchi; Hiromi Ishino; Masataka Tsuge; Yoshifumi Fujimoto; Michio Imamura; Shoichi Takahashi; Kazuaki Chayama
G to A hypermutation of hepatitis B virus.
Hepatology (Baltimore, Md.) 2005;41(3):626-33.
2005: Tomoji Nishioka; Hideyuki Hyogo; Yoshihiro Numata; Atsushi Yamaguchi; Toshiya Kobuke; Daisuke Komichi; Michihiro Nonaka; Motoki Inoue; Yoshitaka Nabeshima; Mami Ogi; Keiko Iwamoto; Tomokazu Ishitobi; Takeyoshi Ajima; Kazuaki Chayama; Susumu Tazuma
A nuclear receptor-mediated choleretic action of fibrates is associated with enhanced canalicular membrane fluidity and transporter activity mediating bile acid-independent bile secretion.
Journal of atherosclerosis and thrombosis 2005;12(4):211-7.
2005: Hideyuki Shima; Toru Hiyama; Shinji Tanaka; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Koji Arihiro; Kazuaki Chayama
Loss of heterozygosity on chromosome 10p14-p15 in colorectal carcinoma.
Pathobiology : journal of immunopathology, molecular and cellular biology 2005;72(4):220-4.
2005: Shigeru Kimura; Yasuhiko Kitadai; Toshio Kuwai; Shinji Tanaka; Jun Hihara; Kazuhiro Yoshida; Tetsuya Toge; Kazuaki Chayama
Expression of p53 protein in esophageal squamous cell carcinoma: relation to hypoxia-inducible factor-1alpha, angiogenesis and apoptosis.
Pathobiology : journal of immunopathology, molecular and cellular biology 2005;72(4):179-85.
2005: Hideharu Okanobu; Jiro Hata; Ken Haruma; Yutaka Mitsuoka; Kayoko Kunihiro; Noriaki Manabe; Shinji Tanaka; Kazuaki Chayama
A classification system of echogenicity for gastrointestinal neoplasms.
Digestion 2005;72(1):8-12.
2005: Yoshitaka Ueno; Shinji Tanaka; Masaru Shimamoto; Yoshihiro Miyanaka; Toru Hiyama; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Masaharu Sumii; Kazuaki Chayama
Infliximab therapy for Crohn's disease in a patient with chronic hepatitis B.
Digestive diseases and sciences 2005;50(1):163-6.
2005: Tomoari Kamada; Jiro Hata; Hiroaki Kusunoki; Masanori Ito; S Tanaka; Y Kawamura; Kazuaki Chayama; Ken Haruma
Eradication of Helicobacter pylori increases the incidence of hyperlipidaemia and obesity in peptic ulcer patients.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2005;37(1):39-43.
2005: Yoshitaka Ueno; Shinji Tanaka; Masaharu Sumii; Sachiko Miyake; Susumu Tazuma; Masaru Taniguchi; Takashi Yamamura; Kazuaki Chayama
Single dose of OCH improves mucosal T helper type 1/T helper type 2 cytokine balance and prevents experimental colitis in the presence of valpha14 natural killer T cells in mice.
Inflammatory bowel diseases 2005;11(1):35-41.
2005: Michio Imamura; Tadashi Ogawa; Yasuyuki Sasaguri; Kazuaki Chayama; Hikaru Ueno
Suppression of macrophage infiltration inhibits activation of hepatic stellate cells and liver fibrogenesis in rats.
Gastroenterology 2005;128(1):138-46.
2005: Yasuhito Tanaka; Kousuke Hanada; Etsuro Orito; Yoshihiro Akahane; Kazuaki Chayama; Hiroshi Yoshizawa; Michio Sata; Nobuo Ohta; Yuzo Miyakawa; Takashi Gojobori; Masashi Mizokami
Molecular evolutionary analyses implicate injection treatment for schistosomiasis in the initial hepatitis C epidemics in Japan.
Journal of hepatology 2005;42(1):47-53.
2005: Hiroaki Sanada; Yukihito Higashi; Chikara Goto; Kazuaki Chayama; Masao Yoshizumi; Taijiro Sueda
Vascular function in patients with lower extremity peripheral arterial disease: a comparison of functions in upper and lower extremities.
Atherosclerosis 2005;178(1):179-85.
2005: Shunji Matsumura; Naohide Oue; Hirofumi Nakayama; Yasuhiko Kitadai; Kazuhiro Yoshida; Yoshiyuki Yamaguchi; Kazue Imai; Kei Nakachi; Keisuke Matsusaki; Kazuaki Chayama; Wataru Yasui
A single nucleotide polymorphism in the MMP-9 promoter affects tumor progression and invasive phenotype of gastric cancer.
Journal of cancer research and clinical oncology 2005;131(1):19-25.
2004: Yasuhiro Oshimo; Kazuya Kuraoka; Hirofumi Nakayama; Yasuhiko Kitadai; Kazuhiro Yoshida; Kazuaki Chayama; Wataru Yasui
Epigenetic inactivation of SOCS-1 by CpG island hypermethylation in human gastric carcinoma.
International journal of cancer. Journal international du cancer 2004;112(6):1003-9.
2004: Shinji Tanaka; Ken Haruma; Masaki Kunihiro; Shinji Nagata; Yasuhiko Kitadai; Noriaki Manabe; Masaharu Sumii; Masaharu Yoshihara; Goro Kajiyama; Kazuaki Chayama
Effects of aged garlic extract (AGE) on colorectal adenomas: a double-blinded study.
Hiroshima journal of medical sciences 2004;53(3-4):39-45.
2004: Masaki Kunihiro; Shinji Tanaka; Masaharu Sumii; Yoshitaka Ueno; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Magnifying colonoscopic features of ulcerative colitis reflect histologic inflammation.
Inflammatory bowel diseases 2004;10(6):737-44.
2004: Mikio Tsuda; Mitsuhiro Sanada; Yukihito Higashi; Yoshiko Hara; Ichiro Kodama; Kazuaki Chayama; Masao Yoshizumi; Koso Ohama
Apolipoprotein E phenotype affects the malondialdehyde-modified LDL concentration and forearm endothelial function in postmenopausal women.
Clinical endocrinology 2004;61(5):619-25.
2004: Toshio Kuwai; Yasuhiko Kitadai; Shinji Tanaka; Tsuyoshi Kuroda; Takehiko Ochiumi; Shunji Matsumura; Naohide Oue; Wataru Yasui; Mika Kaneyasu; Keiji Tanimoto; Masahiko Nishiyama; Kazuaki Chayama
Single nucleotide polymorphism in the hypoxia-inducible factor-1alpha gene in colorectal carcinoma.
Oncology reports 2004;12(5):1033-7.
2004: Daisuke Jitsuiki; Yukihito Higashi; Chikara Goto; Masashi Kimura; Kensuke Noma; Keiko Hara; Keigo Nakagawa; Tetsuya Oshima; Kazuaki Chayama; Masao Yoshizumi
Effect of edaravone, a novel free radical scavenger, on endothelium-dependent vasodilation in smokers.
The American journal of cardiology 2004;94(8):1070-3.
2004: Kazuhiko Tsuboi; Susumu Tazuma; Tomoji Nishioka; Kazuaki Chayama
Partial characterization of cytoprotective mechanisms of lecithin against bile salt-induced bile duct damage.
Journal of gastroenterology 2004;39(10):955-60.
2004: Tomotaka Tanaka; Keiji Tanimoto; Keiko Otani; Kenichi Satoh; Megu Ohtaki; Kazuhiro Yoshida; Tetsuya Toge; Hiroshi Yahata; Shinji Tanaka; Kazuaki Chayama; Yasushi Okazaki; Yoshihide Hayashizaki; Keiko Hiyama; Masahiko Nishiyama
Concise prediction models of anticancer efficacy of 8 drugs using expression data from 12 selected genes.
International journal of cancer. Journal international du cancer 2004;111(4):617-26.
2004: Fumiharu Miura; Hidekazu Hirao; Yukiko Nakano; Hiroki Teragawa; Tetsuji Shingu; Kazuaki Chayama
Improvement of atrial signal-averaged electrocardiographic abnormalities after radiofrequency catheter ablation in persistent atrial flutter.
Japanese heart journal 2004;45(5):761-70.
2004: Masataka Tsuge; Kazuaki Chayama
[Detection of hepatitis B core antibody (including IgM and IgA class antibodies)].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 8():129-33.
2004: Noriaki Manabe; Shinji Tanaka; Atsunori Sasaki; Jiro Hata; Ken Haruma; Kazuaki Chayama
[Differential diagnosis of GERD].
Nihon rinsho. Japanese journal of clinical medicine 2004;62(8):1492-7.
2004: Shigeru Kimura; Yasuhiko Kitadai; Shinji Tanaka; Toshio Kuwai; Jun Hihara; Kazuhiro Yoshida; Tetsuya Toge; Kazuaki Chayama
Expression of hypoxia-inducible factor (HIF)-1alpha is associated with vascular endothelial growth factor expression and tumour angiogenesis in human oesophageal squamous cell carcinoma.
European journal of cancer (Oxford, England : 1990) 2004;40(12):1904-12.
2004: Hideyuki Shima; Toru Hiyama; Shinji Tanaka; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Koji Arihiro; Ken Haruma; Kazuaki Chayama
Frequent loss of heterozygosity on chromosome 10p14-p15 in esophageal dysplasia and squamous cell carcinoma.
Oncology reports 2004;12(2):333-7.
2004: Yoshihiro Numata; Susumu Tazuma; Tomoji Nishioka; Yoshitaka Ueno; Kazuaki Chayama
Immune response in mouse experimental cholangitis associated with colitis induced by dextran sulfate sodium.
Journal of gastroenterology and hepatology 2004;19(8):910-5.
2004: Waka Ohishi; Kazuaki Chayama
[Detection of hepatitis C virus RNA].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 7(Pt 1):214-8.
2004: Tomoji Nishioka; Kazuaki Chayama
[Mechanism of HCV cell entry mediated by envelope and receptor proteins].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 7(Pt 1):195-8.
2004: Toru Hiyama; Shinji Tanaka; Masaharu Yoshihara; Shogo Sasao; Kazuhiro Kose; Hideyuki Shima; Handan Tuncel; Yoshitaka Ueno; Masanori Ito; Yasuhiko Kitadai; Wataru Yasui; Ken Haruma; Kazuaki Chayama
Chromosomal and microsatellite instability in sporadic gastric cancer.
Journal of gastroenterology and hepatology 2004;19(7):756-60.
2004: Hiroki Teragawa; Yukihiro Fukuda; Keiji Matsuda; Keiko Ueda; Yukihito Higashi; T Oshima; Masao Yoshizumi; Kazuaki Chayama
Relation between C reactive protein concentrations and coronary microvascular endothelial function.
Heart (British Cardiac Society) 2004;90(7):750-4.
2004: Seiji Onogawa; Yasuhiko Kitadai; Shinji Tanaka; Toshio Kuwai; Tsuyoshi Kuroda; Kazuaki Chayama
Regulation of vascular endothelial growth factor (VEGF)-C and VEGF-D expression by the organ microenvironment in human colon carcinoma.
European journal of cancer (Oxford, England : 1990) 2004;40(10):1604-9.
2004: Masateru Murakami; Tamito Sasaki; Souichirou Yamasaki; Kenichi Kuwahara; Hideki Miyata; Kazuaki Chayama
Induction of apoptosis by ionizing radiation and CI-1033 in HuCCT-1 cells.
Biochemical and biophysical research communications 2004;319(1):114-9.
2004: H Kai; Masanori Ito; Yasuhiko Kitadai; Shinji Tanaka; Ken Haruma; Kazuaki Chayama
Chronic gastritis with expression of inducible nitric oxide synthase is associated with high expression of interleukin-6 and hypergastrinaemia.
Alimentary pharmacology & therapeutics 2004;19(12):1309-14.
2004: Yasuhiro Oshimo; Naohide Oue; Yoshitsugu Mitani; Hirofumi Nakayama; Yasuhiko Kitadai; Kazuhiro Yoshida; Kazuaki Chayama; Wataru Yasui
Frequent epigenetic inactivation of RIZ1 by promoter hypermethylation in human gastric carcinoma.
International journal of cancer. Journal international du cancer 2004;110(2):212-8.
2004: Shigeto Yoshida; Shinji Tanaka; Daisuke Kamino; Madoka Nakao; Shiro Oka; Yasuhiko Kitadai; Norihiko Hayakawa; Ken Haruma; Kazuaki Chayama
Initial experience with catheter probe US when using a multibending endoscope.
Gastrointestinal endoscopy 2004;59(7):889-94.
2004: Masateru Murakami; Tamito Sasaki; Hideki Miyata; Souichirou Yamasaki; Kenichi Kuwahara; Kazuaki Chayama
Fas and Fas ligand: Expression and soluble circulating levels in bile duct carcinoma.
Oncology reports 2004;11(6):1183-6.
2004: Shinji Tanaka; Shiro Oka; Kazuaki Chayama
[Advances of an internal treatment for early colorectal carcinoma].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2004;101(5):486-94.
2004: Shunji Matsumura; Naohide Oue; Yasuhiko Kitadai; Kazuaki Chayama; Kazuhiro Yoshida; Yoshiyuki Yamaguchi; Tetsuya Toge; Kazue Imai; Kei Nakachi; Wataru Yasui
A single nucleotide polymorphism in the MMP-1 promoter is correlated with histological differentiation of gastric cancer.
Journal of cancer research and clinical oncology 2004;130(5):259-65.
2004: Kayoko Kunihiro; Jiro Hata; Ken Haruma; Noriaki Manabe; Shinji Tanaka; Kazuaki Chayama
Sonographic detection of longitudinal ulcers in Crohn disease.
Scandinavian journal of gastroenterology 2004;39(4):322-6.
2004: S Kim; K Harum; Masanori Ito; Shinji Tanaka; Masaharu Yoshihara; Kazuaki Chayama
Magnifying gastroendoscopy for diagnosis of histologic gastritis in the gastric antrum.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2004;36(4):286-91.
2004: Waka Ohishi; Hiroo Shirakawa; Yoshiiku Kawakami; Sonoko Kimura; Masaya Kamiyasu; Susumu Tazuma; Toshio Nakanishi; Kazuaki Chayama
Identification of rare polymerase variants of hepatitis B virus using a two-stage PCR with peptide nucleic acid clamping.
Journal of medical virology 2004;72(4):558-65.
2004: Yukihito Higashi; Masashi Kimura; Keiko Hara; Kensuke Noma; Daisuke Jitsuiki; Keigo Nakagawa; Tetsuya Oshima; Kazuaki Chayama; Taijiro Sueda; Chikara Goto; Hiroaki Matsubara; Toyoaki Murohara; Masao Yoshizumi
Autologous bone-marrow mononuclear cell implantation improves endothelium-dependent vasodilation in patients with limb ischemia.
Circulation 2004;109(10):1215-8.
2004: Yukiko Nakano; Shumpei Niida; Keigo Dote; Sou Takenaka; Hidekazu Hirao; Fumiharu Miura; Mari Ishida; Tetsuji Shingu; Taijiro Sueda; Masao Yoshizumi; Kazuaki Chayama
Matrix metalloproteinase-9 contributes to human atrial remodeling during atrial fibrillation.
Journal of the American College of Cardiology 2004;43(5):818-25.
2004: Takehiko Ochiumi; Shinji Tanaka; Shiro Oka; Toru Hiyama; Masanori Ito; Yasuhiko Kitadai; Ken Haruma; Kazuaki Chayama
Clinical significance of angiopoietin-2 expression at the deepest invasive tumor site of advanced colorectal carcinoma.
International journal of oncology 2004;24(3):539-47.
2004: Toshio Kuwai; Yasuhiko Kitadai; Shinji Tanaka; Toru Hiyama; Keiji Tanimoto; Kazuaki Chayama
Mutation of the von Hippel-Lindau (VHL) gene in human colorectal carcinoma: association with cytoplasmic accumulation of hypoxia-inducible factor (HIF)-1alpha.
Cancer science 2004;95(2):149-53.
2004: Shiro Oka; Shinji Tanaka; Toru Hiyama; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Clinicopathologic and endoscopic features of colorectal serrated adenoma: differences between polypoid and superficial types.
Gastrointestinal endoscopy 2004;59(2):213-9.
2004: Yasuhiko Kitadai; Seiji Onogawa; Toshio Kuwai; Shunji Matsumura; Hiroshige Hamada; Masanori Ito; Shinji Tanaka; Masaharu Yoshihara; Kazuaki Chayama
Angiogenic switch occurs during the precancerous stage of human esophageal squamous cell carcinoma.
Oncology reports 2004;11(2):315-9.
2004: Atsunori Sasaki; Yasuhiko Kitadai; Masanori Ito; Shinji Tanaka; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Mucin phenotype and background mucosa of intramucosal differentiated-type adenocarcinoma of the stomach.
Oncology 2004;66(5):379-87.
2004: Hiroshi Masuda; Toru Hiyama; Masaharu Yoshihara; Shinji Tanaka; Ken Haruma; Kazuaki Chayama
Characteristics and trends of clarithromycin-resistant Helicobacter pylori isolates in Japan over a decade.
Pathobiology : journal of immunopathology, molecular and cellular biology 2004;71(3):159-63.
2004: Yasuhiro Oshimo; Naohide Oue; Yoshitsugu Mitani; Hirofumi Nakayama; Yasuhiko Kitadai; Kazuhiro Yoshida; Yoshiaki Ito; Kazuaki Chayama; Wataru Yasui
Frequent loss of RUNX3 expression by promoter hypermethylation in gastric carcinoma.
Pathobiology : journal of immunopathology, molecular and cellular biology 2004;71(3):137-43.
2004: Seiji Onogawa; Yasuhiko Kitadai; Shinji Tanaka; Toshio Kuwai; Shigeru Kimura; Kazuaki Chayama
Expression of VEGF-C and VEGF-D at the invasive edge correlates with lymph node metastasis and prognosis of patients with colorectal carcinoma.
Cancer science 2004;95(1):32-9.
2004: Kenichi Kuwahara; Tamito Sasaki; Kensou Kobayashi; Bunjirou Noma; Masahiro Serikawa; Tomohiro Iiboshi; Hideki Miyata; Yukio Kuwada; Masateru Murakami; Souichirou Yamasaki; Ken-Ichi Kariya; Kenji Morinaka; Kazuaki Chayama
Gemcitabine suppresses malignant ascites of human pancreatic cancer: correlation with VEGF expression in ascites.
Oncology reports 2004;11(1):73-80.
2004: Toru Amioka; Yasuhiko Kitadai; Toru Hiyama; Shinji Tanaka; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Expression of human telomerase reverse transcriptase mRNA in esophageal cancers and precancerous lesions.
Oncology reports 2004;11(1):51-5.
2003: Keiji Matsuda; Hiroki Teragawa; Yukihiro Fukuda; Kentaro Ueda; Yukihito Higashi; Kenya Sakai; Fumiharu Miura; Hidekazu Hirao; Togo Yamagata; Masao Yoshizumi; Kazuaki Chayama
Response of the left anterior descending coronary artery to acetylcholine in patients with chest pain and angiographically normal coronary arteries.
The American journal of cardiology 2003;92(12):1394-8.
2003: Mari Ishida; Takafumi Ishida; Hidekatsu Nakashima; Narimasa Miho; Kiyoshi Miyagawa; Kazuaki Chayama; Tetsuya Oshima; Masayuki Kambe; Masao Yoshizumi
Mnk1 is required for angiotensin II-induced protein synthesis in vascular smooth muscle cells.
Circulation research 2003;93(12):1218-24.
2003: Daisuke Komichi; Susumu Tazuma; Tomoji Nishioka; Hideyuki Hyogo; Mizuho Une; Kazuaki Chayama
Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes.
Digestive diseases and sciences 2003;48(12):2315-22.
2003: Yasuhiro Oshimo; Hirofumi Nakayama; Reiko Ito; Yasuhiko Kitadai; Kazuhiro Yoshida; Kazuaki Chayama; Wataru Yasui
Promoter methylation of cyclin D2 gene in gastric carcinoma.
International journal of oncology 2003;23(6):1663-70.
2003: Yasuhiko Kitadai; Atsunori Sasaki; Masanori Ito; Shinji Tanaka; Naohide Oue; Wataru Yasui; Miki Aihara; Kenichi Imagawa; Ken Haruma; Kazuaki Chayama
Helicobacter pylori infection influences expression of genes related to angiogenesis and invasion in human gastric carcinoma cells.
Biochemical and biophysical research communications 2003;311(4):809-14.
2003: Shiro Oka; Shinji Tanaka; Shinji Nagata; Toru Hiyama; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Clinicopathologic features and endoscopic resection of early primary nonampullary duodenal carcinoma.
Journal of clinical gastroenterology 2003;37(5):381-6.
2003: Toru Hiyama; Shinji Tanaka; Hideyuki Shima; Kazuhiro Kose; Handan Tuncel; Masanori Ito; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Somatic mutation in mitochondrial DNA and nuclear microsatellite instability in gastric cancer.
Oncology reports 2003;10(6):1837-41.
2003: Atsushi Ueda; Ryoji Ozono; Tetsuya Oshima; Ai Yano; Masayuki Kambe; Yasuhiro Teranishi; Motoya Katsuki; Kazuaki Chayama
Disruption of the type 2 dopamine receptor gene causes a sodium-dependent increase in blood pressure in mice.
American journal of hypertension 2003;16(10):853-8.
2003: Toru Hiyama; Shinji Tanaka; Hiroshi Masuda; Hideyuki Shima; Kazuhiro Kose; Handan Tuncel; Masanori Ito; Yasuhiko Kitadai; Masaharu Sumii; Naomi Uemura; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Prevalence of Helicobacter pylori resistance to clarithromycin and metronidazole determined by 23S ribosomal RNA and rdxA gene analyses in Hiroshima, Japan.
Journal of gastroenterology and hepatology 2003;18(10):1202-7.
2003: Toshio Kuwai; Shinji Tanaka; Eijiro Kaio; Toru Hiyama; Masanori Ito; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Clinical significance of Fhit expression in development of colorectal carcinoma of various macroscopic types.
International journal of molecular medicine 2003;12(4):437-42.
2003: Eijiro Kaio; Shinji Tanaka; Shiro Oka; Toru Hiyama; Yasuhiko Kitadai; Ken Haruma; Kazuaki Chayama
Clinical significance of thrombospondin-1 expression in relation to vascular endothelial growth factor and interleukin-10 expression at the deepest invasive tumor site of advanced colorectal carcinoma.
International journal of oncology 2003;23(4):901-11.
2003: Shunji Matsumura; Naohide Oue; Reiko Ito; Hirofumi Nakayama; Yasuhiko Kitadai; Hiroshi Yokozaki; Kazuaki Chayama; Wataru Yasui
The promoter methylation status of the DNA repair gene O6-methylguanine-DNA methyltransferase in ulcerative colitis.
Virchows Archiv : an international journal of pathology 2003;443(4):518-23.
2003: Shinji Tanaka; Shinji Nagata; Shiro Oka; Toshio Kuwai; Tadamasa Tamura; Kazuaki Chayama
[Treatment of colorectal carcinoma having submucosal invasion].
Nihon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 7():286-90.
2003: Shiro Oka; Shinji Tanaka; Kazuaki Chayama
[Management of treatment in nodule-aggregating colorectal cancer].
Nihon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 7():139-44.
2003: Akira Tari; Kanji Kodama; Masaharu Sumii; Hiroshi Tani; Koji Sumii; Kazuaki Chayama
Does intragastric nitrite concentration reflect gastric carcinogenesis in Japanese Helicobacter pylori-infected patients?
Digestive diseases and sciences 2003;48(9):1730-6.
2003: Hiroshi Masuda; Toru Hiyama; Masaharu Yoshihara; Shinji Tanaka; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Necessity of multiple gastric biopsies from different sites for detection of clarithromycin-resistant Helicobacter pylori strains.
Scandinavian journal of gastroenterology 2003;38(9):942-6.
2003: Kanji Kodama; Koji Sumii; Masanori Kawano; Tamako Kido; Keiko Nojima; Masaharu Sumii; Ken Haruma; Masaharu Yoshihara; Kazuaki Chayama
Gastric juice nitrite and vitamin C in patients with gastric cancer and atrophic gastritis: is low acidity solely responsible for cancer risk?
European journal of gastroenterology & hepatology 2003;15(9):987-93.
2003: Toru Hiyama; Shinji Tanaka; Hiroshi Masuda; Hideyuki Shima; Kazuhiro Kose; Handan Tuncel; Masanori Ito; Yasuhiko Kitadai; Masaharu Sumii; Naomi Uemura; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
p53 expression, K-ras gene mutation and microsatellite instability in gastric B-cell lymphomas.
Journal of gastroenterology and hepatology 2003;18(9):1047-53.
2003: Toru Hiyama; Shinji Tanaka; Hideyuki Shima; Kazuhiro Kose; Yasuhiko Kitadai; Masanori Ito; Masaharu Sumii; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Frequent loss of heterozygosity on chromosome 10p15, a putative telomerase repressor/senescence gene locus, in gastric cancer.
Oncology reports 2003;10(5):1297-9.
2003: Masateru Murakami; Tamito Sasaki; Yukio Kuwada; Souichirou Yamasaki; Kenichi Kuwahara; Kazuaki Chayama
Prognostic value of p53 and Ki-67 expression in resected or biopsy specimens of bile duct carcinoma.
Oncology reports 2003;10(5):1091-6.
2003: Keishi Kanno; Susumu Tazuma; Kazuaki Chayama
AT1A-deficient mice show less severe progression of liver fibrosis induced by CCl(4).
Biochemical and biophysical research communications 2003;308(1):177-83.
2003: Chikara Goto; Yukihito Higashi; Masashi Kimura; Kensuke Noma; Keiko Hara; Keigo Nakagawa; Mitsutoshi Kawamura; Kazuaki Chayama; Masao Yoshizumi; Isao Nara
Effect of different intensities of exercise on endothelium-dependent vasodilation in humans: role of endothelium-dependent nitric oxide and oxidative stress.
Circulation 2003;108(5):530-5.
2003: Waka Ohishi; Mikiya Kitamoto; Hiroshi Aikata; Koji Kamada; Yoshiiku Kawakami; H Ishihara; Masaya Kamiyasu; Toshio Nakanishi; Susumu Tazuma; Kazuaki Chayama
Impact of aging on the development of hepatocellular carcinoma in patients with hepatitis C virus infection in Japan.
Scandinavian journal of gastroenterology 2003;38(8):894-900.
2003: Hiroki Teragawa; Yukihiro Fukuda; Keiji Matsuda; Hidekazu Hirao; Yukihito Higashi; Togo Yamagata; Tetsuya Oshima; Hideo Matsuura; Kazuaki Chayama
Myocardial bridging increases the risk of coronary spasm.
Clinical cardiology 2003;26(8):377-83.
2003: Toru Hiyama; Shinji Tanaka; Hideyuki Shima; Kazuhiro Kose; Yasuhiko Kitadai; Masanori Ito; Masaharu Sumii; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Somatic mutation of mitochondrial DNA in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer.
International journal of molecular medicine 2003;12(2):169-74.
2003: Yukihito Higashi; Satoshi Sasaki; Keigo Nakagawa; Masashi Kimura; Kensuke Noma; Shota Sasaki; Keiko Hara; Hideo Matsuura; Chikara Goto; Tetsuya Oshima; Kazuaki Chayama; Masao Yoshizumi
Low body mass index is a risk factor for impaired endothelium-dependent vasodilation in humans: role of nitric oxide and oxidative stress.
Journal of the American College of Cardiology 2003;42(2):256-63.
2003: Tamako Kido; Koji Sumii; Masanori Kawano; Masaharu Sumii; Masaharu Yoshihara; Kazuaki Chayama
Food deprivation enhances somatostatin and somatostatin receptor subtype expression in rat colon.
Regulatory peptides 2003;114(2-3):167-73.
2003: Nobuyuki Asada; Yoshiharu Tanaka; Yasutaka Hayashido; Shigeaki Toratani; Mikio Kan; Mikiya Kitamoto; Toshio Nakanishi; Goro Kajiyama; Kazuaki Chayama; Tetsuji Okamoto
Expression of fibroblast growth factor receptor genes in human hepatoma-derived cell lines.
In vitro cellular & developmental biology. Animal 2003;39(7):321-8.
2003: Masanori Ito; Shinji Tanaka; Sunjin Kim; Toshio Kuwai; Norimasa Matsutani; Tomoari Kamada; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
The specific expression of hypoxia inducible factor-1alpha in human gastric mucosa induced by nonsteroidal anti-inflammatory drugs.
Alimentary pharmacology & therapeutics 2003;18 Suppl 1():90-8.
2003: Ryoji Takahashi; Shinji Tanaka; Toru Hiyama; Masanori Ito; Yasuhiko Kitadai; Masaharu Sumii; Ken Haruma; Kazuaki Chayama
Hypoxia-inducible factor-1alpha expression and angiogenesis in gastrointestinal stromal tumor of the stomach.
Oncology reports 2003;10(4):797-802.
2003: Junko Tanaka; Hiromitsu Kumada; Kenji Ikeda; Kazuaki Chayama; Masaaki Mizui; Kunihiko Hino; Keiko Katayama; Junko Kumagai; Yutaka Komiya; Yuzo Miyakawa; Hiroshi Yoshizawa
Natural histories of hepatitis C virus infection in men and women simulated by the Markov model.
Journal of medical virology 2003;70(3):378-86.
2003: Atsunori Sasaki; Ken Haruma; Noriaki Manabe; Shinji Tanaka; Masaharu Yoshihara; Kazuaki Chayama
Long-term observation of reflux oesophagitis developing after Helicobacter pylori eradication therapy.
Alimentary pharmacology & therapeutics 2003;17(12):1529-34.
2003: Kuniharu Nakai; Susumu Tazuma; Tomoji Nishioka; Kazuaki Chayama
Inhibition of cholesterol crystallization under bilirubin deconjugation: partial characterization of mechanisms whereby infected bile accelerates pigment stone formation.
Biochimica et biophysica acta 2003;1632(1-3):48-54.
2003: Toshio Kuwai; Yasuhiko Kitadai; Shinji Tanaka; Seiji Onogawa; Norimasa Matsutani; Eijiro Kaio; Masanori Ito; Kazuaki Chayama
Expression of hypoxia-inducible factor-1alpha is associated with tumor vascularization in human colorectal carcinoma.
International journal of cancer. Journal international du cancer 2003;105(2):176-81.
2003: Masaki Miyamoto; Ken Haruma; Masaharu Yoshihara; Toru Hiyama; Masaaki Sumioka; Takashi Nishisaka; Shinji Tanaka; Kazuaki Chayama
Nodular gastritis in adults is caused by Helicobacter pylori infection.
Digestive diseases and sciences 2003;48(5):968-75.
2003: Kenichi Kuwahara; Tamito Sasaki; Yukio Kuwada; Masateru Murakami; Souichirou Yamasaki; Kazuaki Chayama
Expressions of angiogenic factors in pancreatic ductal carcinoma: a correlative study with clinicopathologic parameters and patient survival.
Pancreas 2003;26(4):344-9.
2003: Masashi Kimura; Yukihito Higashi; Keiko Hara; Kensuke Noma; Satoshi Sasaki; Keigo Nakagawa; Chikara Goto; Tetsuya Oshima; Masao Yoshizumi; Kazuaki Chayama
PDE5 inhibitor sildenafil citrate augments endothelium-dependent vasodilation in smokers.
Hypertension 2003;41(5):1106-10.
2003: Kensuke Noma; Yukihito Higashi; Daisuke Jitsuiki; Keiko Hara; Masashi Kimura; Keigo Nakagawa; Chikara Goto; Tetsuya Oshima; Masao Yoshizumi; Kazuaki Chayama
Smoking activates rho-kinase in smooth muscle cells of forearm vasculature in humans.
Hypertension 2003;41(5):1102-5.
2003: Mitsuhiro Sanada; Yukihito Higashi; Keigo Nakagawa; Ichiro Kodama; Mikio Tsuda; Nobutaka Nagai; Kazuaki Chayama; Koso Ohama
Comparison of forearm endothelial function between premenopausal and postmenopausal women with or without hypercholesterolemia.
Maturitas 2003;44(4):307-15.
2003: Tomoari Kamada; Ken Haruma; Hiroaki Kusunoki; Masaki Miyamoto; Masanori Ito; Yasuhiko Kitadai; Masaharu Yoshihara; Kazuaki Chayama; Kazumasa Tahara; Yuzuru Kawamura
Significance of an exaggerated meal-stimulated gastrin response in pathogenesis of Helicobacter pylori-negative duodenal ulcer.
Digestive diseases and sciences 2003;48(4):644-51.
2003: Hideyuki Shima; Shinji Tanaka; Toshio Kuwai; Toru Hiyama; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Minute depressed colon cancer with submucosal invasion.
Gastrointestinal endoscopy 2003;57(4):564-5.
2003: Masahiro Ohta; Yasuhiko Kitadai; Shinji Tanaka; Masaharu Yoshihara; Wataru Yasui; Naofumi Mukaida; Ken Haruma; Kazuaki Chayama
Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human gastric carcinomas.
International journal of oncology 2003;22(4):773-8.
2003: Yukio Kuwada; Tamito Sasaki; Kenji Morinaka; Yasuhiko Kitadai; Naofumi Mukaida; Kazuaki Chayama
Potential involvement of IL-8 and its receptors in the invasiveness of pancreatic cancer cells.
International journal of oncology 2003;22(4):765-71.
2003: Koji Yoshida; Shuichi Ueno; Toshiyasu Iwao; Souichirou Yamasaki; Akira Tsuchida; Ken Ohmine; Ruri Ohki; Young Lim Choi; Koji Koinuma; Tomoaki Wada; Jun Ota; Yoshihiro Yamashita; Kazuaki Chayama; Kazuhiro Sato; Hiroyuki Mano
Screening of genes specifically activated in the pancreatic juice ductal cells from the patients with pancreatic ductal carcinoma.
Cancer science 2003;94(3):263-70.
2003: Mitsuhiro Sanada; Yukihito Higashi; Keigo Nakagawa; Mikio Tsuda; Ichiro Kodama; Masashi Kimura; Kazuaki Chayama; Koso Ohama
A comparison of low-dose and standard-dose oral estrogen on forearm endothelial function in early postmenopausal women.
The Journal of clinical endocrinology and metabolism 2003;88(3):1303-9.
2003: Hideharu Okanobu; Jiro Hata; Ken Haruma; Mutsuhiro Hara; Kenjiro Nakamura; Shinji Tanaka; Kazuaki Chayama
Giant gastric folds: differential diagnosis at US.
Radiology 2003;226(3):686-90.
2003: Waka Ohishi; Kazuaki Chayama
[Hepatitis D virus infection].
Nihon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 2():245-8.
2003: Takashi Noda; Wataru Shimizu; Kouichi Tanaka; Kazuaki Chayama
Prominent J wave and ST segment elevation: serial electrocardiographic changes in accidental hypothermia.
Journal of cardiovascular electrophysiology 2003;14(2):223.
2003: Noriaki Manabe; Ken Haruma; Jiro Hata; K Nakamura; Shinji Tanaka; Kazuaki Chayama
Autonomic nerve dysfunction is closely associated with the abnormalities of esophageal motility in reflux esophagitis.
Scandinavian journal of gastroenterology 2003;38(2):159-63.
2003: Atsunori Sasaki; Yasuhiko Kitadai; Masanori Ito; Masaharu Sumii; Shinji Tanaka; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Helicobacter pylori infection influences tumor growth of human gastric carcinomas.
Scandinavian journal of gastroenterology 2003;38(2):153-8.
2003: Keiji Matsuda; Hiroki Teragawa; Yukihiro Fukuda; Keigo Nakagawa; Yukihito Higashi; Kazuaki Chayama
Leptin causes nitric-oxide independent coronary artery vasodilation in humans.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26(2):147-52.
2003: Seiji Onogawa; Shinji Tanaka; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Small rectal carcinoid with lymph node metastasis diagnosed prior to treatment.
European journal of gastroenterology & hepatology 2003;15(2):195-7.
2003: Susumu Tazuma; Tomoji Nishioka; Hidenori Ochi; Hideyuki Hyogo; Yasushi Sunami; Kuniharu Nakai; Kazuhiko Tsuboi; Yasumasa Asamoto; Minoru Sakomoto; Yoshihiro Numata; Keishi Kanno; Atsushi Yamaguchi; Toshiya Kobuke; Daisuke Komichi; Yoshihiro Nonaka; Kazuaki Chayama
Impaired gallbladder mucosal function in aged gallstone patients suppresses gallstone recurrence after successful extracorporeal shockwave lithotripsy.
Journal of gastroenterology and hepatology 2003;18(2):157-61.
2003: Waka Ohishi; Kazuaki Chayama
Rare quasispecies in the YMDD motif of hepatitis B virus detected by polymerase chain reaction with peptide nucleic acid clamping.
Intervirology 2003;46(6):355-61.
2003: Makoto Sanomura; Shinji Tanaka; Masanori Ito; Kazuaki Chayama
Depressed-type, early duodenal carcinoma (carcinoma in situ) treated by endoscopic mucosal resection.
Journal of gastroenterology 2003;38(8):813-5.
2003: Masaki Miyamoto; Ken Haruma; Masaharu Yoshihara; Masaaki Sumioka; Tomoari Kamada; Masanori Ito; Hiroshi Masuda; Takashi Nishisaka; Shinji Tanaka; Kazuaki Chayama
Isolated granulomatous gastritis successfully treated by Helicobacter pylori eradication: a possible association between granulomatous gastritis and Helicobacter pylori.
Journal of gastroenterology 2003;38(4):371-5.
2003: Kuninushi Kiyohira; Masaharu Yoshihara; Masanori Ito; Ken Haruma; Shinji Tanaka; Kazuaki Chayama
Serum pepsinogen concentration as a marker of Helicobacter pyloriinfection and the histologic grade of gastritis; evaluation of gastric mucosa by serum pepsinogen levels.
Journal of gastroenterology 2003;38(4):332-8.
2003: Ryoji Takahashi; Shinji Tanaka; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Expression of vascular endothelial growth factor and angiogenesis in gastrointestinal stromal tumor of the stomach.
Oncology 2003;64(3):266-74.
2003: Toru Hiyama; Shinji Tanaka; Ken Haruma; Kazuaki Chayama
[The roles of H. pylori infection and K-ras gene mutation in gastric carcinogenesis].
Nihon rinsho. Japanese journal of clinical medicine 2003;61(1):46-9.
2003: Satoshi Kurisu; Ryoji Ozono; Tetsuya Oshima; Masayuki Kambe; Takafumi Ishida; Hiroshi Sugino; Hideo Matsuura; Kazuaki Chayama; Yasuhiro Teranishi; Osamu Iba; Katsuya Amano; Hiroaki Matsubara
Cardiac angiotensin II type 2 receptor activates the kinin/NO system and inhibits fibrosis.
Hypertension 2003;41(1):99-107.
2003: Eijiro Kaio; Shinji Tanaka; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Clinical significance of angiogenic factor expression at the deepest invasive site of advanced colorectal carcinoma.
Oncology 2003;64(1):61-73.
2002: Yukihito Higashi; Keigo Nakagawa; Masashi Kimura; Kensuke Noma; Keiko Hara; Satoshi Sasaki; Chikara Goto; Tetsuya Oshima; Kazuaki Chayama; Masao Yoshizumi
Circadian variation of blood pressure and endothelial function in patients with essential hypertension:a comparison of dippers and non-dippers.
Journal of the American College of Cardiology 2002;40(11):2039-43.
2002: Hiroki Teragawa; Hideo Matsuura; Kazuaki Chayama; Tetsuya Oshima
Mechanisms responsible for vasodilation upon magnesium infusion in vivo: clinical evidence.
Magnesium research : official organ of the International Society for the Development of Research on Magnesium 2002;15(3-4):241-6.
2002: Yukiko Nakano; Takafumi Ishida; Ryoji Ozono; Hideo Matsuura; Yuji Yamamoto; Masayuki Kambe; Kazuaki Chayama; Tetsuya Oshima
A frameshift mutation of beta subunit of epithelial sodium channel in a case of isolated Liddle syndrome.
Journal of hypertension 2002;20(12):2379-82.
2002: Masahiro Ohta; Yasuhiko Kitadai; Shinji Tanaka; Masaharu Yoshihara; Wataru Yasui; Naofumi Mukaida; Ken Haruma; Kazuaki Chayama
Monocyte chemoattractant protein-1 expression correlates with macrophage infiltration and tumor vascularity in human esophageal squamous cell carcinomas.
International journal of cancer. Journal international du cancer 2002;102(3):220-4.
2002: M Miyamoto; Ken Haruma; Masaharu Yoshihara; Masaaki Sumioka; Takashi Nishisaka; Shinji Tanaka; K Inoue; Kazuaki Chayama
Five cases of nodular gastritis and gastric cancer: a possible association between nodular gastritis and gastric cancer.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2002;34(11):819-20.
2002: Yousuke Kawasaki; Akira Tsuchida; Tamito Sasaki; Souichirou Yamasaki; Yukio Kuwada; Masateru Murakami; Kazuaki Chayama
Irsogladine malate up-regulates gap junctional intercellular communication between pancreatic cancer cells via PKA pathway.
Pancreas 2002;25(4):373-7.
2002: Hiroki Teragawa; Yukihiro Fukuda; Keiji Matsuda; Yukihito Higashi; Togo Yamagata; Hideo Matsuura; Kazuaki Chayama
Effect of alcohol consumption on endothelial function in men with coronary artery disease.
Atherosclerosis 2002;165(1):145-52.
2002: S Oka; Shinji Tanaka; Toru Hiyama; Yasuhiko Kitadai; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Human telomerase reverse transcriptase, p53 and Ki-67 expression and apoptosis in colorectal serrated adenoma.
Scandinavian journal of gastroenterology 2002;37(10):1194-200.
2002: Mitsuhiro Sanada; Yukihito Higashi; Keigo Nakagawa; Mikio Tsuda; Ichiro Kodama; Masashi Kimura; Kazuaki Chayama; Koso Ohama
Hormone replacement effects on endothelial function measured in the forearm resistance artery in normocholesterolemic and hypercholesterolemic postmenopausal women.
The Journal of clinical endocrinology and metabolism 2002;87(10):4634-41.
2002: Kenya Sakai; Togo Yamagata; Hiroki Teragawa; Hideo Matsuura; Kazuaki Chayama
Nicorandil-induced preconditioning as evidenced by troponin T measurements after coronary angioplasty in patients with stable angina pectoris.
Japanese heart journal 2002;43(5):443-53.
2002: Koji Kamada; Mikiya Kitamoto; Hiroshi Aikata; Yoshiiku Kawakami; Hirotaka Kono; Michio Imamura; Toshio Nakanishi; Kazuaki Chayama
Combination of transcatheter arterial chemoembolization using cisplatin-lipiodol suspension and percutaneous ethanol injection for treatment of advanced small hepatocellular carcinoma.
American journal of surgery 2002;184(3):284-90.
2002: Mitsuhiro Sanada; Yukihito Higashi; Keigo Nakagawa; Mikio Tsuda; Ichiro Kodama; Nobutaka Nagai; Kazuaki Chayama; Koso Ohama
Combination therapy of low-dose medroxyprogesterone acetate and oral estrogen does not affect endothelial function in the forearms of postmenopausal women.
Menopause (New York, N.Y.) 2002;9(5):360-6.
2002: Shinji Tanaka; Shinji Nagata; Shiro Oka; Toshio Kuwai; Tadamasa Tamura; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Ken Haruma; Kazuaki Chayama
Determining depth of invasion by VN pit pattern analysis in submucosal colorectal carcinoma.
Oncology reports 2002;9(5):1005-8.
2002: Noriaki Manabe; Masaharu Yoshihara; Atsunori Sasaki; Shinji Tanaka; Ken Haruma; Kazuaki Chayama
Clinical characteristics and natural history of patients with low-grade reflux esophagitis.
Journal of gastroenterology and hepatology 2002;17(9):949-54.
2002: Masanori Ito; Ken Haruma; Tomoari Kamada; M Mihara; Sunjin Kim; Yasuhiko Kitadai; Masaharu Sumii; Shinji Tanaka; Masaharu Yoshihara; Kazuaki Chayama
Helicobacter pylori eradication therapy improves atrophic gastritis and intestinal metaplasia: a 5-year prospective study of patients with atrophic gastritis.
Alimentary pharmacology & therapeutics 2002;16(8):1449-56.
2002: Shinji Nagata; Shinji Tanaka; Ken Haruma; Yasuhiko Kitadai; Masaharu Yoshihara; Fumio Shimamoto; Kazuaki Chayama
Advanced colorectal carcinoma smaller than 10 mm in maximum diameter with special reference to clinicopathologic and molecular features: a report of 3 cases.
Gastrointestinal endoscopy 2002;56(2):299-303.
2002: Toru Hiyama; Shinji Tanaka; Yasuhiko Kitadai; Masanori Ito; Masaharu Sumii; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
p53 Codon 72 polymorphism in gastric cancer susceptibility in patients with Helicobacter pylori-associated chronic gastritis.
International journal of cancer. Journal international du cancer 2002;100(3):304-8.
2002: Kenya Sakai; Togo Yamagata; Hiroki Teragawa; Hideo Matsuura; Kazuaki Chayama
Preconditioning effect during coronary angioplasty in patients with stable angina pectoris.
Internal medicine (Tokyo, Japan) 2002;41(7):509-15.
2002: T Amioka; Yasuhiko Kitadai; Shinji Tanaka; Ken Haruma; Masaharu Yoshihara; Wataru Yasui; Kazuaki Chayama
Vascular endothelial growth factor-C expression predicts lymph node metastasis of human gastric carcinomas invading the submucosa.
European journal of cancer (Oxford, England : 1990) 2002;38(10):1413-9.
2002: Yukihito Higashi; Shota Sasaki; Keigo Nakagawa; Hideo Matsuura; Tetsuya Oshima; Kazuaki Chayama
Endothelial function and oxidative stress in renovascular hypertension.
The New England journal of medicine 2002;346(25):1954-62.
2002: Noriaki Manabe; Ken Haruma; Jiro Hata; Hiroaki Kusunoki; Shigeto Yoshida; K Futagami; Shinji Tanaka; Kazuaki Chayama
Evaluation of esophageal motility by endosonography using a miniature ultrasonographic probe in patients with reflux esophagitis.
Scandinavian journal of gastroenterology 2002;37(6):674-8.
2002: S Aoki; Ken Haruma; Hiroaki Kusunoki; Jiro Hata; M Hara; Shigeto Yoshida; Shinji Tanaka; Kazuaki Chayama
Evaluation of gastric emptying measured with the 13C-octanoic acid breath test in patients with functional dyspepsia: comparison with ultrasonography.
Scandinavian journal of gastroenterology 2002;37(6):662-6.
2002: Hideharu Okanobu; Jiro Hata; Ken Haruma; S Matsumura; Shigeto Yoshida; Yasuhiko Kitadai; Shinji Tanaka; Kazuaki Chayama
Preoperative assessment of gastric cancer vascularity by flash echo imaging.
Scandinavian journal of gastroenterology 2002;37(5):608-12.
2002: Masanori Ito; Ken Haruma; Shunji Kaya; Hirohisa Kai; Hiroshi Masuda; Masahiro Ohta; Masaharu Sumii; Shinji Tanaka; Masaharu Yoshihara; Kazuaki Chayama
Implication of anti-parietal cell antibody levels in gastrointestinal diseases, including gastric carcinogenesis.
Digestive diseases and sciences 2002;47(5):1080-5.
2002: Yukihito Higashi; Satoshi Sasaki; Keigo Nakagawa; Masashi Kimura; Shota Sasaki; Kensuke Noma; Keiko Hara; Hideo Matsuura; Chikara Goto; Tetsuya Oshima; Kazuaki Chayama
Severity of hypertension affects improved resistance artery endothelial function by angiotensin-converting enzyme inhibition.
Journal of cardiovascular pharmacology 2002;39(5):668-76.
2002: Mikiya Kitamoto; Michio Imamura; Koji Kamada; Hiroshi Aikata; Yoshiiku Kawakami; Akiko Matsumoto; Yoshika Kurihara; Hirotaka Kono; Hiroo Shirakawa; Toshio Nakanishi; Katsuhide Ito; Kazuaki Chayama
Balloon-occluded retrograde transvenous obliteration of gastric fundal varices with hemorrhage.
AJR. American journal of roentgenology 2002;178(5):1167-74.
2002: Seiji Onogawa; Shinji Tanaka; Shiro Oka; Masao Morihara; Yasuhiko Kitadai; Masaharu Sumii; Masaharu Yoshihara; Fumio Shimamoto; Ken Haruma; Kazuaki Chayama
Clinical significance of angiogenesis in rectal carcinoid tumors.
Oncology reports 2002;9(3):489-94.
2002: Ken Haruma; Masanori Ito; S Kido; Noriaki Manabe; Yasuhiko Kitadai; M Sumii; S Tanaka; Masaharu Yoshihara; Kazuaki Chayama
Long-term rebamipide therapy improves Helicobacter pylori-associated chronic gastritis.
Digestive diseases and sciences 2002;47(4):862-7.
2002: Yukihito Higashi; Shota Sasaki; Keigo Nakagawa; Yukihiro Fukuda; Hideo Matsuura; Tetsuya Oshima; Kazuaki Chayama
Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals.
American journal of hypertension 2002;15(4 Pt 1):326-32.
2002: Shota Sasaki; Yukihito Higashi; Keigo Nakagawa; Masashi Kimura; Kensuke Noma; Satoshi Sasaki; Keiko Hara; Hideo Matsuura; Chikara Goto; Tetsuya Oshima; Kazuaki Chayama
A low-calorie diet improves endothelium-dependent vasodilation in obese patients with essential hypertension.
American journal of hypertension 2002;15(4 Pt 1):302-9.
2002: Masaki Miyamoto; Ken Haruma; Toru Hiyama; Tomoari Kamada; Hiroshi Masuda; Fumio Shimamoto; Kazuhiko Inoue; Kazuaki Chayama
High incidence of B-cell monoclonality in follicular gastritis: a possible association between follicular gastritis and MALT lymphoma.
Virchows Archiv : an international journal of pathology 2002;440(4):376-80.
2002: Kenya Sakai; Togo Yamagata; Hiroki Teragawa; Hideo Matsuura; Kazuaki Chayama
Nicorandil enhances myocardial tolerance to ischemia without progressive collateral recruitment during coronary angioplasty.
Circulation journal : official journal of the Japanese Circulation Society 2002;66(4):317-22.
2002: Keigo Nakagawa; Yukihito Higashi; Shota Sasaki; Tetsuya Oshima; Hideo Matsuura; Kazuaki Chayama
Leptin causes vasodilation in humans.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(2):161-5.
2002: Masanori Ito; Ken Haruma; Shunji Kaya; Tomoari Kamada; Sunjin Kim; Atsunori Sasaki; Masaharu Sumii; Shinji Tanaka; Masaharu Yoshihara; Kazuaki Chayama
Role of anti-parietal cell antibody in Helicobacter pylori-associated atrophic gastritis: evaluation in a country of high prevalence of atrophic gastritis.
Scandinavian journal of gastroenterology 2002;37(3):287-93.
2002: Masaru Nakamura; Ken Haruma; Tomoari Kamada; Mitsuhiro Mihara; Masaharu Yoshihara; Masaaki Sumioka; Toshiyuki Fukuhara; Kazuaki Chayama
Cigarette smoking promotes atrophic gastritis in Helicobacter pylori-positive subjects.
Digestive diseases and sciences 2002;47(3):675-81.
2002: Yukihiro Fukuda; Hiroki Teragawa; Keiji Matsuda; Togo Yamagata; Hideo Matsuura; Kazuaki Chayama
Tetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolaemia.
Heart (British Cardiac Society) 2002;87(3):264-9.
2002: Yukiko Nakano; Tetsuya Oshima; Ryoji Ozono; Atsushi Ueda; Yasuo Oue; Hideo Matsuura; Mitsuhiro Sanada; Koso Ohama; Kazuaki Chayama; Masayuki Kambe
Estrogen replacement suppresses function of thrombin stimulated platelets by inhibiting Ca(2+) influx and raising cyclic adenosine monophosphate.
Cardiovascular research 2002;53(3):634-41.
2002: Minoru Sakomoto; Susumu Tazuma; Kazuaki Chayama
Less hydrophobic phosphatidylcholine species simplify biliary vesicle morphology, but induce bile metastability with a broad spectrum of crystal forms.
The Biochemical journal 2002;362(Pt 1):105-12.
2002: Toru Hiyama; Ken Haruma; Yasuhiko Kitadai; Hiroshi Masuda; Masaki Miyamoto; Shinji Tanaka; Masaharu Yoshihara; Fumio Shimamoto; Kazuaki Chayama
K-ras mutation in helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer.
International journal of cancer. Journal international du cancer 2002;97(5):562-6.
2002: Kanji Kodama; Koji Sumii; Masanori Kawano; Tamako Kido; Keiko Nojima; Masaharu Sumii; Ken Haruma; Masaharu Yoshihara; Kazuaki Chayama
Helicobacter pylori infection increases serum nitrate and nitrite more prominently than serum pepsinogens.
Helicobacter 2002;7(1):9-13.
2002: Masanori Ito; Ken Haruma; Shunji Kaya; Tomoari Kamada; Sunjin Kim; Atsunori Sasaki; Masaharu Sumii; Shinji Tanaka; Masaharu Yoshihara; Siegfried Wagner; Kazuaki Chayama
Serological comparison of serum pepsinogen and anti-parietal cell antibody levels between Japanese and German patients.
European journal of gastroenterology & hepatology 2002;14(2):123-7.
2002: Tomoari Kamada; Kazuaki Chayama; Ken Haruma; Masaharu Yoshihara; Masanori Ito; Yasuhiko Kitadai; Yuzuru Kawamura
[Non-ulcer dyspepsia and H. pylori].
Nihon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 2():774-8.
2002: Tomoari Kamada; Kazuaki Chayama; Ken Haruma; Masaharu Yoshihara; Masanori Ito; Yasuhiko Kitadai; Yuzuru Kawamura
[The analysis of the recurrence ulcer after H. pylori eradication].
Nihon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 2():501-5.
2002: Yukihito Higashi; Satoshi Sasaki; Keigo Nakagawa; Masashi Kimura; Shota Sasaki; Kensuke Noma; Hideo Matsuura; Keiko Hara; Chikara Goto; Tetsuya Oshima; Kazuaki Chayama
Excess norepinephrine impairs both endothelium-dependent and -independent vasodilation in patients with pheochromocytoma.
Hypertension 2002;39(2 Pt 2):513-8.
2002: Masanori Ito; Shinji Tanaka; Masaharu Yoshihara; Kazuaki Chayama; Ken Haruma
Single administration of ecabet sodium diminishes the level of delta-13CO2 in urea breath test.
Journal of gastroenterology 2002;37(8):674-5.
2002: Kazuaki Chayama
Management of chronic hepatitis C and prevention of hepatocellular carcinoma.
Journal of gastroenterology 2002;37 Suppl 13():69-73.
2002: Yukihiro Fukuda; Hiroki Teragawa; Keiji Matsuda; Togo Yamagata; Hideo Matsuura; Kazuaki Chayama
Tetrahydrobiopterin improves coronary endothelial function, but does not prevent coronary spasm in patients with vasospastic angina.
Circulation journal : official journal of the Japanese Circulation Society 2002;66(1):58-62.
2002: Akira Furudoi; Shinji Tanaka; Ken Haruma; Yasuhiko Kitadai; Masaharu Yoshihara; Kazuaki Chayama; Fumio Shimamoto
Clinical significance of vascular endothelial growth factor C expression and angiogenesis at the deepest invasive site of advanced colorectal carcinoma.
Oncology 2002;62(2):157-66.
2002: Yukihito Higashi; Kazuaki Chayama
Renal endothelial dysfunction and hypertension.
Journal of diabetes and its complications 2002;16(1):103-7.
2002: Susumu Tazuma; Kazuaki Chayama
[Hepatitis C].
Nihon rinsho. Japanese journal of clinical medicine 2002;60 Suppl 1():213-9.
2001: Kuniharu Nakai; Susumu Tazuma; H Ochi; Kazuaki Chayama
Does bilirubin play a role in the pathogenesis of both cholesterol and pigment gallstone formation? Direct and indirect influences of bilirubin on bile lithogenicity.
Biochimica et biophysica acta 2001;1534(2-3):78-84.
2001: Hiroki Teragawa; M Kato; J Kurokawa; Togo Yamagata; Hideo Matsuura; Kazuaki Chayama
Endothelial dysfunction is an independent factor responsible for vasospastic angina.
Clinical science (London, England : 1979) 2001;101(6):707-13.
2001: E Miyoshi; Ken Haruma; Toru Hiyama; Shinji Tanaka; Masaharu Yoshihara; Fumio Shimamoto; Kazuaki Chayama
Microsatellite instability is a genetic marker for the development of multiple gastric cancers.
International journal of cancer. Journal international du cancer 2001;95(6):350-3.
2001: Hiroki Teragawa; M Kato; J Kurokawa; Togo Yamagata; Hideo Matsuura; Kazuaki Chayama
Usefulness of flow-mediated dilation of the brachial artery and/or the intima-media thickness of the carotid artery in predicting coronary narrowing in patients suspected of having coronary artery disease.
The American journal of cardiology 2001;88(10):1147-51.
2001: Yukihito Higashi; S Sasaki; Keigo Nakagawa; Masashi Kimura; Kensuke Noma; Satoshi Sasaki; Keiko Hara; Hideo Matsuura; Kazuaki Chayama; Tetsuya Oshima
Sodium chloride loading does not alter endothelium-dependent vasodilation of forearm vasculature in either salt-sensitive or salt-resistant patients with essential hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension 2001;24(6):711-6.
2001: K Futagami; Jiro Hata; Ken Haruma; N Yamashita; Shigeto Yoshida; Shinji Tanaka; Kazuaki Chayama
Extracorporeal ultrasound is an effective diagnostic alternative to endoscopic ultrasound for gastric submucosal tumours.
Scandinavian journal of gastroenterology 2001;36(11):1222-6.
2001: Yasumasa Asamoto; Susumu Tazuma; Hidenori Ochi; Kazuaki Chayama; Hidenori Suzuki
Bile-salt hydrophobicity is a key factor regulating rat liver plasma-membrane communication: relation to bilayer structure, fluidity and transporter expression and function.
The Biochemical journal 2001;359(Pt 3):605-10.
2001: Yukiko Nakano; Tetsuya Oshima; Satoshi Sasaki; Yukihito Higashi; Ryoji Ozono; Sou Takenaka; Fumiharu Miura; Hidekazu Hirao; Hideo Matsuura; Kazuaki Chayama; Masayuki Kambe
Calorie restriction reduced blood pressure in obesity hypertensives by improvement of autonomic nerve activity and insulin sensitivity.
Journal of cardiovascular pharmacology 2001;38 Suppl 1():S69-74.
2001: Yukihito Higashi; Satoshi Sasaki; Keigo Nakagawa; Hideo Matsuura; Kazuaki Chayama; Tetsuya Oshima
Effect of obesity on endothelium-dependent, nitric oxide-mediated vasodilation in normotensive individuals and patients with essential hypertension.
American journal of hypertension 2001;14(10):1038-45.
2001: S Nagata; Shinji Tanaka; Ken Haruma; Yasuhiko Kitadai; Masaharu Yoshihara; Fumio Shimamoto; Nobuoki Kohno; Kazuaki Chayama
MUC1 and cathepsin D expression in early colorectal carcinoma showing V type pit pattern.
International journal of oncology 2001;19(4):665-72.
2001: X Chen; Ken Haruma; Tomoari Kamada; N Hartori; Masaharu Yoshihara; Yasuhiko Kitadai; Shinji Tanaka; Koji Sumii; Kazuaki Chayama
A low 13C-urea breath test value is associated with increased risk of gastric cancer.
Journal of gastroenterology 2001;36(9):601-5.
2001: Norimasa Matsutani; Hiroshi Yokozaki; Eiichi Tahara; Hidetoshi Tahara; Hiroki Kuniyasu; Ken Haruma; Kazuaki Chayama; Wataru Yasui; E Tahara
Expression of telomeric repeat binding factor 1 and 2 and TRF1-interacting nuclear protein 2 in human gastric carcinomas.
International journal of oncology 2001;19(3):507-12.
2001: Yasuhiko Kitadai; Toru Amioka; Ken Haruma; Shinji Tanaka; Masaharu Yoshihara; K Sumii; Norimasa Matsutani; Wataru Yasui; Kazuaki Chayama
Clinicopathological significance of vascular endothelial growth factor (VEGF)-C in human esophageal squamous cell carcinomas.
International journal of cancer. Journal international du cancer 2001;93(5):662-6.
2001: S Kido; Yasuhiko Kitadai; N Hattori; Ken Haruma; T Kido; M Ohta; Shinji Tanaka; Masaharu Yoshihara; K Sumii; Y Ohmoto; Kazuaki Chayama
Interleukin 8 and vascular endothelial growth factor -- prognostic factors in human gastric carcinomas?
European journal of cancer (Oxford, England : 1990) 2001;37(12):1482-7.
2001: Toru Hiyama; Ken Haruma; Yasuhiko Kitadai; Hiroshi Masuda; Masaki Miyamoto; Masanori Ito; Tomoari Kamada; Shinji Tanaka; Naomi Uemura; Masaharu Yoshihara; Koji Sumii; Fumio Shimamoto; Kazuaki Chayama
Clinicopathological features of gastric mucosa-associated lymphoid tissue lymphoma: a comparison with diffuse large B-cell lymphoma without a mucosa-associated lymphoid tissue lymphoma component.
Journal of gastroenterology and hepatology 2001;16(7):734-9.
2001: Shinji Tanaka; Ken Haruma; Shiro Oka; R Takahashi; Masaki Kunihiro; Yasuhiko Kitadai; Masaharu Yoshihara; Fumio Shimamoto; Kazuaki Chayama
Clinicopathologic features and endoscopic treatment of superficially spreading colorectal neoplasms larger than 20 mm.
Gastrointestinal endoscopy 2001;54(1):62-6.
2001: N Murachima; Kenji Ikeda; Masahiro Kobayashi; Satoshi Saitoh; Kazuaki Chayama; Akihito Tsubota; Yoshiyuki Suzuki; Fumitaka Suzuki; Yasuji Arase; Hiromitsu Kumada
Incidence of the appearance of the red color sign on esophageal varices and its predictive factors: long-term observations of 359 patients with cirrhosis.
Journal of gastroenterology 2001;36(6):368-74.
2001: Susumu Tazuma; K Horikawa; Hidenori Ochi; Tomoji Nishioka; Yasushi Sunami; S Yasumiba; Yasumasa Asamoto; Kazuhiko Tsuboi; Kuniharu Nakai; Minoru Sakomoto; Keishi Kanno; Atsushi Yamaguchi; Yoshihiro Numata; Kazuaki Chayama
Dose-dependent conjugation of sulfobromophthalein and hepatic transit time in bile fistula rats: role of the microtubule-dependent vesicle pathway.
Digestive diseases and sciences 2001;46(6):1285-9.
2001: Toru Hiyama; Ken Haruma; Yasuhiko Kitadai; Masanori Ito; Hiroshi Masuda; Masaki Miyamoto; Shinji Tanaka; Masaharu Yoshihara; Koji Sumii; Fumio Shimamoto; Kazuaki Chayama
Helicobacter pylori eradication therapy for high-grade mucosa-associated lymphoid tissue lymphomas of the stomach with analysis of p53 and K-ras alteration and microsatellite instability.
International journal of oncology 2001;18(6):1207-12.
2001: Yasushi Sunami; Susumu Tazuma; Kazuaki Chayama
Is a role of phospholipase A(2) in cholesterol gallstone formation phospholipid species-dependent?
Biochimica et biophysica acta 2001;1532(1-2):51-9.
2001: Masanori Ito; Ken Haruma; T Kamada; Yasuhiko Kitadai; T Hidaka; T Tsuda; H Komatsu; T Fukuhara; Masaharu Yoshihara; Kazuaki Chayama
Reduction in the incidence of Helicobacter pylori-associated carcinoma in Japanese young adults.
Oncology reports 2001;8(3):633-6.
2001: Yoshinori Fujimoto; T Sasaki; A Tsuchida; Kazuaki Chayama
Angiotensin II type 1 receptor expression in human pancreatic cancer and growth inhibition by angiotensin II type 1 receptor antagonist.
FEBS letters 2001;495(3):197-200.
2001: Kenji Ikeda; Satoshi Saitoh; Masahiro Kobayashi; Yoshiyuki Suzuki; Fumitaka Suzuki; Akihito Tsubota; Yasuji Arase; N Murashima; Kazuaki Chayama; Hiromitsu Kumada
Long-term interferon therapy for 1 year or longer reduces the hepatocellular carcinogenesis rate in patients with liver cirrhosis caused by hepatitis C virus: a pilot study.
Journal of gastroenterology and hepatology 2001;16(4):406-15.
2001: Fumitaka Suzuki; Kazuaki Chayama; Akihito Tsubota; Norio Akuta; Takashi Someya; Masahiro Kobayashi; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Twice-daily administration of interferon-beta for chronic hepatitis C is not superior to a once-daily regimen.
Journal of gastroenterology 2001;36(4):242-7.
2001: S Yasumiba; Susumu Tazuma; Hidenori Ochi; Kazuaki Chayama; Goro Kajiyama
Cyclosporin A reduces canalicular membrane fluidity and regulates transporter function in rats.
The Biochemical journal 2001;354(Pt 3):591-6.
2001: Toru Hiyama; Ken Haruma; Yasuhiko Kitadai; Masanori Ito; Hiroshi Masuda; Masaki Miyamoto; Shinji Tanaka; Masaharu Yoshihara; Koji Sumii; Fumio Shimamoto; Kazuaki Chayama
Microsatellite instability at D18S61 is associated with no regression of gastric mucosa-associated lymphoid tissue lymphoma after Helicobacter pylori eradication.
Oncology reports 2001;8(2):293-7.
2001: Toru Hiyama; Ken Haruma; Yasuhiko Kitadai; Masanori Ito; Hiroshi Masuda; Masaki Miyamoto; Shinji Tanaka; Masaharu Yoshihara; Koji Sumii; Fumio Shimamoto; Kazuaki Chayama
c-myc gene mutation in gastric mucosa-associated lymphoid tissue (MALT) lymphoma and diffuse large B-cell lymphoma.
Oncology reports 2001;8(2):289-92.
2001: Akihito Tsubota; Yasuji Arase; Satoshi Saitoh; Masahiro Kobayashi; Yoshiyuki Suzuki; Fumitaka Suzuki; Kazuaki Chayama; N Murashima; Kenji Ikeda; M Kobayashi; Hiromitsu Kumada
Lamivudine therapy for spontaneously occurring severe acute exacerbation in chronic hepatitis B virus infection: a preliminary study.
The American journal of gastroenterology 2001;96(2):557-62.
2001: Yukihito Higashi; Mitsuhiro Sanada; Satoshi Sasaki; Keigo Nakagawa; Chikara Goto; Hideo Matsuura; Koso Ohama; Kazuaki Chayama; Tetsuya Oshima
Effect of estrogen replacement therapy on endothelial function in peripheral resistance arteries in normotensive and hypertensive postmenopausal women.
Hypertension 2001;37(2 Pt 2):651-7.
2001: Takashi Someya; Yoshiyuki Suzuki; Yasuji Arase; Masahiro Kobayashi; Fumitaka Suzuki; Akihito Tsubota; Satoshi Saitoh; Kazuaki Chayama; N Murashima; Kenji Ikeda; Hiromitsu Kumada
Interferon therapy for flare-up of hepatitis B virus infection after emergence of lamivudine-induced YMDD motif mutant.
Journal of gastroenterology 2001;36(2):133-6.
2001: Tamito Sasaki; Y Fujimoto; Akira Tsuchida; Yousuke Kawasaki; Yukio Kuwada; Kazuaki Chayama
Activation of peroxisome proliferator-activated receptor gamma inhibits the growth of human pancreatic cancer.
Pathobiology : journal of immunopathology, molecular and cellular biology 2001;69(5):258-65.
2001: Norimasa Matsutani; Hiroshi Yokozaki; E Tahara; Hidetoshi Tahara; Hiroki Kuniyasu; Yasuhiko Kitadai; Ken Haruma; Kazuaki Chayama; Eiichi Tahara; Wataru Yasui
Expression of MRE11 complex (MRE11, RAD50, NBS1) and hRap1 and its relation with telomere regulation, telomerase activity in human gastric carcinomas.
Pathobiology : journal of immunopathology, molecular and cellular biology 2001;69(4):219-24.
2001: Fumitaka Suzuki; Kazuaki Chayama; Akihito Tsubota; Norio Akuta; Takashi Someya; Masahiro Kobayashi; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; Hiromitsu Kumada
Pathogenic significance and organic virus levels in patients infected with TT virus.
Intervirology 2001;44(5):291-7.
2000: Kazuaki Chayama; Fumitaka Suzuki; Akihito Tsubota; Masahiro Kobayashi; Yasuji Arase; Satoshi Saitoh; Yoshiyuki Suzuki; N Murashima; Kenji Ikeda; N Takahashi; M Kinoshita; Hiromitsu Kumada
Association of amino acid sequence in the PKR-eIF2 phosphorylation homology domain and response to interferon therapy.
Hepatology (Baltimore, Md.) 2000;32(5):1138-44.
2000: Kenji Ikeda; Yasuji Arase; Satoshi Saitoh; Masahiro Kobayashi; Yoshiyuki Suzuki; Fumitaka Suzuki; Akihito Tsubota; Kazuaki Chayama; N Murashima; Hiromitsu Kumada
Interferon beta prevents recurrence of hepatocellular carcinoma after complete resection or ablation of the primary tumor-A prospective randomized study of hepatitis C virus-related liver cancer.
Hepatology (Baltimore, Md.) 2000;32(2):228-32.
2000: Masahiro Kobayashi; Kenji Ikeda; Satoshi Saitoh; Fumitaka Suzuki; Akihito Tsubota; Yoshiyuki Suzuki; Yasuji Arase; N Murashima; Kazuaki Chayama; Hiromitsu Kumada
Incidence of primary cholangiocellular carcinoma of the liver in japanese patients with hepatitis C virus-related cirrhosis.
Cancer 2000;88(11):2471-7.
2000: M Kobyashi; Kazuaki Chayama; Yasuji Arase; Akihito Tsubota; Satoshi Saitoh; Yoshiyuki Suzuki; Masahiro Kobayashi; N Murashima; Kenji Ikeda; M Hagiwara; R Hashimoto; M Nakagawa; M Matsuda; Hiromitsu Kumada
Progressive and sufficient decrease of hepatitis B core antibody can predict the disappearance of hepatitis B virus DNA in Japanese patients with hepatitis B surface antigen clearance.
Journal of gastroenterology 2000;35(10):753-7.
2000: Masahiro Kobayashi; Kenji Ikeda; Norio Akuta; Takashi Someya; Fumitaka Suzuki; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; Kazuaki Chayama; Hiromitsu Kumada
Relationship between five-year histological outcome and serial changes in serum alanine aminotransferase in patients with biochemical and virological relapse after interferon treatment for chronic hepatitis C.
Intervirology 2000;43(3):174-9.
2000: Yasuji Arase; Kenji Ikeda; Kazuaki Chayama; N Murashima; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; M Kobayashi; Fumitaka Suzuki; Hiromitsu Kumada
Increased response rate to interferon therapy after a second course in hepatitis C patients who show relapse after the initial course.
Journal of gastroenterology 2000;35(8):607-12.
2000: Kenji Ikeda; Satoshi Saitoh; Masahiro Kobayashi; Yoshiyuki Suzuki; Fumitaka Suzuki; Akihito Tsubota; Yasuji Arase; Kazuaki Chayama; N Murashima; Hiromitsu Kumada
Hepatic vascular side effects of styrene maleic acid neocarzinostatin in the treatment of hepatocellular carcinoma.
Journal of gastroenterology 2000;35(5):353-60.
2000: Yasuji Arase; Kenji Ikeda; Kazuaki Chayama; N Murashima; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; M Kobayashi; Fumitaka Suzuki; Hiromitsu Kumada
Fluctuation patterns of HCV-RNA serum level in patients with chronic hepatitis C.
Journal of gastroenterology 2000;35(3):221-5.
1999: Yasuji Arase; Kenji Ikeda; N Murashima; Kazuaki Chayama; Akihito Tsubota; I Koida; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; M Kobayashi; Hiromitsu Kumada
Time course of histological changes in patients with a sustained biochemical and virological response to corticosteroid withdrawal therapy for chronic hepatitis B.
The American journal of gastroenterology 1999;94(11):3304-9.
1999: Yasuji Arase; Kenji Ikeda; Kazuaki Chayama; N Murashima; Akihito Tsubota; I Nakamura; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; M Kobayashi; M Kobayashi; Hiromitsu Kumada
Clinical and virological features of chronic hepatitis C carriers with normal alanine aminotransferase levels despite positive serum HCV-RNA after interferon therapy.
Journal of gastroenterology 1999;34(5):594-9.
1999: Akihito Tsubota; Hiromitsu Kumada; Yasuji Arase; Kazuaki Chayama; Satoshi Saitoh; Kenji Ikeda; Masahiro Kobayashi; Yoshiyuki Suzuki; N Murashima
Combined ursodeoxycholic acid and glycyrrhizin therapy for chronic hepatitis C virus infection: a randomized controlled trial in 170 patients.
European journal of gastroenterology & hepatology 1999;11(10):1077-83.
1999: Y Hoshida; S Saitoh; N Murashima; A Ogawa; Yasuji Arase; M Kobayashi; Y Suzuki; A Tsubota; Kazuaki Chayama; Kenji Ikeda; H Kumada
Vaginal variceal hemorrhage in a patient with primary biliary cirrhosis: a case successfully treated by balloon-occluded retrograde transvenous obliteration.
The American journal of gastroenterology 1999;94(10):3081-3.
1999: M Hashimoto; Kazuaki Chayama; Masahiro Kobayashi; Akihito Tsubota; Yasuji Arase; Satoshi Saitoh; Yoshiyuki Suzuki; Kenji Ikeda; M Matsuda; H Koike; M Kobayashi; H Handa; Hiromitsu Kumada
Fluctuations of hepatitis C virus load are not related to amino acid substitutions in hypervariable region 1 and interferon sensitivity determining region.
Journal of medical virology 1999;58(3):247-55.
1999: Yasuji Arase; Kenji Ikeda; Kazuaki Chayama; N Murashima; Akihito Tsubota; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; M Kobayashi; M Kobayashi; Hiromitsu Kumada
Efficacy and changes of the nonstructural 5A GENE by prolonged interferon therapy for patients with hepatitis C virus genotype 1b and a high level of serum HCV-RNA.
Internal medicine (Tokyo, Japan) 1999;38(6):461-6.
1999: Masahiro Kobayashi; Kazuaki Chayama; Yasuji Arase; M Kobayashi; Akihito Tsubota; Yoshiyuki Suzuki; I Koida; Satoshi Saitoh; N Murashima; Kenji Ikeda; H Koike; M Hashimoto; M Kobayashi; Hiromitsu Kumada
Prevalence of TT virus before and after blood transfusion in patients with chronic liver disease treated surgically for hepatocellular carcinoma.
Journal of gastroenterology and hepatology 1999;14(4):358-63.
1999: Kenji Ikeda; Satoshi Saitoh; Yasuji Arase; Kazuaki Chayama; Yoshiyuki Suzuki; Masahiro Kobayashi; Akihito Tsubota; I Nakamura; N Murashima; Hiromitsu Kumada; M Kawanishi
Effect of interferon therapy on hepatocellular carcinogenesis in patients with chronic hepatitis type C: A long-term observation study of 1,643 patients using statistical bias correction with proportional hazard analysis.
Hepatology (Baltimore, Md.) 1999;29(4):1124-30.
1999: Kazuaki Chayama; Masahiro Kobayashi; Akihito Tsubota; M Kobayashi; Yasuji Arase; Yoshiyuki Suzuki; Satoshi Saitoh; N Murashima; Kenji Ikeda; K Okamoto; M Hashimoto; M Matsuda; H Koike; M Kobayashi; Hiromitsu Kumada
Susceptibility of TT virus to interferon therapy.
The Journal of general virology 1999;80 ( Pt 3)():631-4.
1999: Y Hoshida; Kenji Ikeda; S Saito; Masahiro Kobayashi; M Kobayashi; Yoshiyuki Suzuki; Akihito Tsubota; I Koida; Yasuji Arase; N Murashima; Kazuaki Chayama; Hiromitsu Kumada
[The efficacy and prognosis of transcatheter chemoembolization for hepatocellular carcinoma in the elderly].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1999;96(2):142-6.
1998: Kenji Ikeda; Satoshi Saitoh; Yoshiyuki Suzuki; Masahiro Kobayashi; Akihito Tsubota; I Koida; M Kobayashi; Yasuji Arase; Kazuaki Chayama; N Murashima; Hiromitsu Kumada
Relationship of angiographic finding with neovascular structure detected by immunohistochemical staining of alpha-smooth muscle actin in small hepatocellular carcinoma.
Journal of gastroenterology and hepatology 1998;13(12):1266-73.
1998: Akihito Tsubota; Hiromitsu Kumada; K Takaki; Kazuaki Chayama; Masahiro Kobayashi; M Kobayashi; Yoshiyuki Suzuki; Satoshi Saitoh; Yasuji Arase; N Murashima; Kenji Ikeda
Deletions in the hepatitis B virus core gene may influence the clinical outcome in hepatitis B e antigen-positive asymptomatic healthy carriers.
Journal of medical virology 1998;56(4):287-93.
1998: Yasuji Arase; Kenji Ikeda; N Murashima; Kazuaki Chayama; Akihito Tsubota; I Koida; Yoshiyuki Suzuki; Satoshi Saitoh; Masahiro Kobayashi; M Kobayashi; M Kobayashi; Hiromitsu Kumada
Glomerulonephritis in autopsy cases with hepatitis C virus infection.
Internal medicine (Tokyo, Japan) 1998;37(10):836-40.
1998: Masahiro Kobayashi; Kazuaki Chayama; M Fukuda; Akihito Tsubota; Yoshiyuki Suzuki; Yasuji Arase; I Koida; Satoshi Saitoh; N Murashima; Kenji Ikeda; H Koike; M Hashimoto; Y Miyano; M Kobayashi; Hiromitsu Kumada
Biochemical and histological features of hepatitis G virus infection.
Journal of gastroenterology and hepatology 1998;13(8):767-72.
1998: Kenji Ikeda; Satoshi Saitoh; Yoshiyuki Suzuki; Masahiro Kobayashi; Akihito Tsubota; I Koida; Yasuji Arase; M Fukuda; Kazuaki Chayama; N Murashima; Hiromitsu Kumada
Disease progression and hepatocellular carcinogenesis in patients with chronic viral hepatitis: a prospective observation of 2215 patients.
Journal of hepatology 1998;28(6):930-8.
1998: Kazuaki Chayama; Yoshiyuki Suzuki; Masahiro Kobayashi; M Kobayashi; Akihito Tsubota; M Hashimoto; Y Miyano; H Koike; M Kobayashi; I Koida; Yasuji Arase; Satoshi Saitoh; N Murashima; Kenji Ikeda; Hiromitsu Kumada
Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy.
Hepatology (Baltimore, Md.) 1998;27(6):1711-6.
1998: M Fukuda; Kazuaki Chayama; Akihito Tsubota; Masahiro Kobayashi; M Hashimoto; Y Miyano; H Koike; M Kobayashi; I Koida; Yasuji Arase; Satoshi Saitoh; N Murashima; Kenji Ikeda; Hiromitsu Kumada
Predictive factors in eradicating hepatitis C virus using a relatively small dose of interferon.
Journal of gastroenterology and hepatology 1998;13(4):412-8.
1998: Masahiro Kobayashi; Hiromitsu Kumada; Yasuji Arase; Kazuaki Chayama; M Kobayashi; Akihito Tsubota; I Koida; Satoshi Saitoh; Yoshiyuki Suzuki; N Murashima; Kenji Ikeda; Y Miyano; K Mizoshita; M Matsuda; H Koike; M Hashimoto
Usefulness of hepatitis C virus RNA counts by second generation HCV bDNA-probe in chronic hepatitis C based on the HCV genotype.
Journal of gastroenterology 1998;33(2):223-8.
1998: Kenji Ikeda; Satoshi Saitoh; Yoshiyuki Suzuki; Masahiro Kobayashi; Akihito Tsubota; M Fukuda; I Koida; Yasuji Arase; Kazuaki Chayama; N Murashima; Hiromitsu Kumada
Interferon decreases hepatocellular carcinogenesis in patients with cirrhosis caused by the hepatitis B virus: a pilot study.
Cancer 1998;82(5):827-35.
1997: Kenji Ikeda; Satoshi Saitoh; Yoshiyuki Suzuki; Akihito Tsubota; I Koida; Masahiro Kobayashi; Yasuji Arase; Kazuaki Chayama; N Murashima; Hiromitsu Kumada
Effect of arterial administration of a high molecular weight anti-tumor agent, styrene maleic acid neocarzinostatin, for multiple small liver cancer--a pilot study.
Journal of gastroenterology 1997;32(4):513-20.
1997: Akihito Tsubota; Hiromitsu Kumada; Kazuaki Chayama; Yasuji Arase; Satoshi Saitoh; I Koida; Yoshiyuki Suzuki; Masahiro Kobayashi; N Murashima; Kenji Ikeda
Time course of histological changes in patients with a sustained biochemical and virological response to interferon-alpha therapy for chronic hepatitis C virus infection.
Journal of hepatology 1997;27(1):49-55.
1997: T Nakamura; Satoshi Saitoh; Kenji Ikeda; Masahiro Kobayashi; Yoshiyuki Suzuki; Akihito Tsubota; I Koida; Yasuji Arase; Kazuaki Chayama; N Murashima; Hiromitsu Kumada
[Cranial MRI in the patients with chronic liver disease (CLD)].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1997;94(3):157-62.
1997: Kazuaki Chayama; Akihito Tsubota; Masahiro Kobayashi; K Okamoto; M Hashimoto; Y Miyano; H Koike; M Kobayashi; I Koida; Yasuji Arase; Satoshi Saitoh; Yoshiyuki Suzuki; N Murashima; Kenji Ikeda; Hiromitsu Kumada
Pretreatment virus load and multiple amino acid substitutions in the interferon sensitivity-determining region predict the outcome of interferon treatment in patients with chronic genotype 1b hepatitis C virus infection.
Hepatology (Baltimore, Md.) 1997;25(3):745-9.
1996: Kenji Ikeda; Kazuaki Chayama; Satoshi Saitoh; I Koida; Y Suzuki; A Tsubota; M Kobayashi; Yasuji Arase; N Murashima; H Kumada
Hepatitis C virus subtype 3b infection in a hospital in Japan: epidemiological study.
Journal of gastroenterology 1996;31(6):801-5.
1996: A Tsubota; H Kumada; Kazuaki Chayama; Yasuji Arase; Satoshi Saitoh; I Koida; N Murashima; Y Suzuki; M Kobayashi; K Takagi; M Kobayashi; Kenji Ikeda
Relationship between pretreatment viremia level and response to interferon-alpha therapy in chronic hepatitis C differs in viral type 1 and 2 infections.
Digestive diseases and sciences 1996;41(10):1925-32.
1996: Yasuji Arase; Kazuaki Chayama; A Tsubota; N Murashima; Y Suzuki; I Koida; M Kobayashi; S Saitoh; Kenji Ikeda; H Kumada; M Kobayashi; H Suzuki
A randomized, double-blind, controlled trial of natural interferon-beta therapy for e-antigen-negative chronic hepatitis B patients with abnormal transaminase levels.
Journal of gastroenterology 1996;31(4):559-64.
1996: Kazuaki Chayama; A Tsubota; M Kobayashi; M Hashimoto; Y Miyano; H Koike; M Kobayashi; I Koida; Yasuji Arase; Satoshi Saitoh; N Murashima; Kenji Ikeda; H Kumada
A pilot study of corticosteroid priming for lymphoblastoid interferon alfa in patients with chronic hepatitis C.
Hepatology (Baltimore, Md.) 1996;23(5):953-7.
1995: Kazuaki Chayama; A Tsubota; Yasuji Arase; Satoshi Saitoh; Kenji Ikeda; T Matsumoto; M Hashimoto; M Kobayashi; M Kanda; T Morinaga
Genotype, slow decrease in virus titer during interferon treatment and high degree of sequence variability of hypervariable region are indicative of poor response to interferon treatment in patients with chronic hepatitis type C.
Journal of hepatology 1995;23(6):648-53.
1995: Kazuaki Chayama
[Detection of hepatitis B core antigen and antibody].
Nihon rinsho. Japanese journal of clinical medicine 1995;53 Suppl(Pt 2):253-7.
1995: Satoshi Saitoh; Kenji Ikeda; I Koida; Y Suzuki; M Kobayashi; A Tsubota; Yasuji Arase; Kazuaki Chayama; N Murashima; H Kumada
Diagnosis of hepatocellular carcinoma by concanavalin A affinity electrophoresis of serum alpha-fetoprotein.
Cancer 1995;76(7):1139-44.
1995: Kazuaki Chayama
[Nucleotide sequence substitutions of hepatitis C virus].
Nihon rinsho. Japanese journal of clinical medicine 1995;53 Suppl(Pt 1):657-61.
1995: Kazuaki Chayama
[Genotyping of hepatitis C virus by polymerase chain reaction with a mixed primer set derived from nucleotide sequences of NS5 region].
Nihon rinsho. Japanese journal of clinical medicine 1995;53 Suppl(Pt 1):321-5.
1995: Kazuaki Chayama
[Detection of hepatitis C virus RNA with reverse transcription-nested polymerase chain reaction].
Nihon rinsho. Japanese journal of clinical medicine 1995;53 Suppl(Pt 1):276-80.
1995: Satoshi Saitoh; Kenji Ikeda; I Koida; A Tsubota; Yasuji Arase; Kazuaki Chayama; H Kumada
Serial hemodynamic measurements in well-differentiated hepatocellular carcinomas.
Hepatology (Baltimore, Md.) 1995;21(6):1530-4.
1995: Kenji Ikeda; S Saitoh; I Koida; A Tsubota; Yasuji Arase; Kazuaki Chayama; H Kumada
A prospective randomized evaluation of a compound of tegafur and uracil as an adjuvant chemotherapy for hepatocellular carcinoma treated with transcatheter arterial chemoembolization.
American journal of clinical oncology 1995;18(3):204-10.
1995: Kazuaki Chayama; M Kobayashi; A Tsubota; I Koida; Yasuji Arase; Satoshi Saitoh; Kenji Ikeda; H Kumada
Molecular analysis of intraspousal transmission of hepatitis C virus.
Journal of hepatology 1995;22(4):431-9.
1994: Kazuaki Chayama; A Tsubota; I Koida; Yasuji Arase; Satoshi Saitoh; Kenji Ikeda; H Kumada
Nucleotide sequence of hepatitis C virus (type 3b) isolated from a Japanese patient with chronic hepatitis C.
The Journal of general virology 1994;75 ( Pt 12)():3623-8.
1994: Satoshi Saitoh; Kenji Ikeda; I Koida; A Tsubota; Yasuji Arase; Kazuaki Chayama; H Kumada
Serum des-gamma-carboxyprothrombin concentration determined by the avidin-biotin complex method in small hepatocellular carcinomas.
Cancer 1994;74(11):2918-23.
1994: M Kobayashi; H Kumada; Kazuaki Chayama; Yasuji Arase; S Saitou; A Tsubota; I Koida; Kenji Ikeda; M Hashimoto; S Iwasaki
Prevalence of HCV genotype among patients with chronic liver diseases in the Tokyo metropolitan area.
Journal of gastroenterology 1994;29(5):583-7.
1994: Satoshi Saitoh; Kenji Ikeda; I Koida; A Tsubota; Yasuji Arase; Kazuaki Chayama; H Kumada
Small hepatocellular carcinoma: evaluation of portal blood flow with CT during arterial portography performed with balloon occlusion of the hepatic artery.
Radiology 1994;193(1):67-70.
1994: S Saito; Kenji Ikeda; I Koida; A Tsubota; Yasuji Arase; Kazuaki Chayama; M Kanda; M Kobayashi; H Kumada
[The diagnosis of hepatocellular carcinoma determined by pattern of AFP bands separated by Con A affinity electrophoresis].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1994;91(8):1301-8.
1994: Kenji Ikeda; Satoshi Saitoh; I Koida; A Tsubota; Yasuji Arase; Kazuaki Chayama; H Kumada
Imaging diagnosis of small hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 1994;20(1 Pt 1):82-7.
1994: Kazuaki Chayama
[Serial amino acid sequence change in the hypervariable region of hepatitis C virus].
Nihon rinsho. Japanese journal of clinical medicine 1994;52(7):1716-20.
1994: Yasuji Arase; H Kumada; Kazuaki Chayama; A Tsubota; I Koida; Kenji Ikeda; Satoshi Saitoh; T Matsumoto; M Kobayashi
Interferon retreatment of nonresponders with HCV-RNA-positive chronic hepatitis C.
Journal of gastroenterology 1994;29(3):299-304.
1994: A Tsubota; Kazuaki Chayama; Kenji Ikeda; A Yasuji; I Koida; Satoshi Saitoh; M Hashimoto; S Iwasaki; M Kobayashi; K Hiromitsu
Factors predictive of response to interferon-alpha therapy in hepatitis C virus infection.
Hepatology (Baltimore, Md.) 1994;19(5):1088-94.
1994: Kazuaki Chayama; Yasuji Arase; I Koida; A Tsubota; Satoshi Saitoh; Kenji Ikeda; T Matsumoto; M Kanda; S Iwasaki; M Kobayashi
Antiviral effect of lymphoblastoid interferon-alpha on hepatitis C virus in patients with chronic hepatitis type C.
Journal of gastroenterology and hepatology 1994;9(2):128-33.
1993: A Tsubota; Kazuaki Chayama; Yasuji Arase; I Koida; Satoshi Saitoh; Kenji Ikeda; S Iwasaki; T Matsumoto; M Kobayashi; H Kumada
Factors useful in predicting the response to interferon therapy in chronic hepatitis C.
Journal of gastroenterology and hepatology 1993;8(6):535-9.
1993: Kenji Ikeda; Satoshi Saitoh; I Koida; Yasuji Arase; A Tsubota; Kazuaki Chayama; H Kumada; M Kawanishi
A multivariate analysis of risk factors for hepatocellular carcinogenesis: a prospective observation of 795 patients with viral and alcoholic cirrhosis.
Hepatology (Baltimore, Md.) 1993;18(1):47-53.
1993: Kenji Ikeda; Satoshi Saitoh; I Koida; A Tsubota; Yasuji Arase; Kazuaki Chayama; H Kumada
Diagnosis and follow-up of small hepatocellular carcinoma with selective intraarterial digital subtraction angiography.
Hepatology (Baltimore, Md.) 1993;17(6):1003-7.
1993: Kazuaki Chayama; A Tsubota; Yasuji Arase; Satoshi Saitoh; Kenji Ikeda; T Matsumoto; Y Sakai; M Kobayashi; T Morinaga; H Kumada
Effect of lymphoblastoid alfa-interferon in patients with chronic hepatitis C having different genotypic subtype of hepatitis C virus.
Gastroenterologia Japonica 1993;28 Suppl 5():45-7.
1993: Kazuaki Chayama; A Tsubota; Yasuji Arase; Satoshi Saitoh; I Koida; Kenji Ikeda; T Matsumoto; M Kobayashi; S Iwasaki; S Koyama
Genotypic subtyping of hepatitis C virus.
Journal of gastroenterology and hepatology 1993;8(2):150-6.
1993: Kenji Ikeda; Satoshi Saitoh; A Tsubota; Yasuji Arase; Kazuaki Chayama; H Kumada; G Watanabe; M Tsurumaru
Risk factors for tumor recurrence and prognosis after curative resection of hepatocellular carcinoma.
Cancer 1993;71(1):19-25.
1992: Yasuji Arase; H Kumada; Kazuaki Chayama; A Tsubota; Kenji Ikeda; Satoshi Saitoh; Y Sakai; T Matsumoto; M Kobayashi
Alanine aminotransferase and HCV-RNA responses following interferon therapy of HCV-RNA positive chronic hepatitis.
Gastroenterologia Japonica 1992;27(5):646-51.
1992: T Matsumoto; Kazuaki Chayama; H Kumada
[Detection of hepatitis C virus RNA with nested polymerase chain reaction by a single tube method].
Nihon rinsho. Japanese journal of clinical medicine 1992;50 Suppl():274-8.
1991: Kenji Ikeda; H Kumada; Satoshi Saitoh; Yasuji Arase; Kazuaki Chayama
Effect of repeated transcatheter arterial embolization on the survival time in patients with hepatocellular carcinoma. An analysis by the Cox proportional hazard model.
Cancer 1991;68(10):2150-4.
1991: Kazuaki Chayama; Yasuji Arase; S Saito; Kenji Ikeda; H Kumada; T Matsumoto; M Kobayashi; Y Sakai; T Morinaga
[Clinical features and viral markers in patients with chronic hepatitis positive for both HBs antigen and anti-C-100 antibody].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1991;88(9):2113-8.
1991: Kazuaki Chayama; Satoshi Saitoh; Yasuji Arase; Kenji Ikeda; T Matsumoto; Y Sakai; M Kobayashi; M Unakami; T Morinaga; H Kumada
Effect of interferon administration on serum hepatitis C virus RNA in patients with chronic hepatitis C.
Hepatology (Baltimore, Md.) 1991;13(6):1040-3.
1989: Kenji Ikeda; H Kumada; Yasuji Arase; Kazuaki Chayama; Satoshi Saitoh; H Komeichi; A Yoshiba; M Irimoto
[Remission state and five-year survival after transcatheter arterial embolization therapy in patients with hepatocellular carcinoma].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1989;86(9):2215-22.
1989: Satoshi Saitoh; H Kumada; Kenji Ikeda; Kazuaki Chayama; Yasuji Arase; A Yoshiba; M Unakami
[Seven cases of acute exacerbation accompanied with icterus and ascites in chronic type B hepatitis].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1989;86(2):261-4.
1988: Kenji Ikeda; H Kumada; Yasuji Arase; Kazuaki Chayama; T Gunji; A Yoshiba; M Irimoto
[Risk factors for side effects of long-term administration of 5-fluorouracil derivatives in patients with hepatocellular carcinoma associated with liver cirrhosis--relationship with serum concentration of anti-tumor agents and side effect].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1988;85(11):2411-9.
1987: Kenji Ikeda; H Kumada; Yasuji Arase; I Nakamura; Kazuaki Chayama; N Murashima; K Takeuchi; M Nakajima; A Yoshiba; M Irimoto
[Effects and side effects of long-term administration of oral antitumor agents in patients with hepatocellular carcinoma--especially, relation to aggravation of liver function].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 1987;84(10):2377-85.