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Chris Cheeseman

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Melinda Wuest; Brendan J Trayner; Tina N Grant; Hans-Soenke Jans; John R Mercer; David Murray; Frederick G West; Alexander J B McEwan; Frank Wuest; Chris I Cheeseman
Radiopharmacological evaluation of 6-deoxy-6-[18F]fluoro-D-fructose as a radiotracer for PET imaging of GLUT5 in breast cancer.
Brendan J Trayner; Tina N Grant; Frederick G West; Chris I Cheeseman
Synthesis and characterization of 6-deoxy-6-fluoro-D-fructose as a potential compound for imaging breast cancer with PET.
Andrei Manolescu; Robert Augustin; Kelle H Moley; Chris I Cheeseman
A highly conserved hydrophobic motif in the exofacial vestibule of fructose transporting SLC2A proteins acts as a critical determinant of their substrate selectivity.

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All Publications

2011: Melinda Wuest; Brendan J Trayner; Tina N Grant; Hans-Soenke Jans; John R Mercer; David Murray; Frederick G West; Alexander J B McEwan; Frank Wuest; Chris I Cheeseman
Radiopharmacological evaluation of 6-deoxy-6-[18F]fluoro-D-fructose as a radiotracer for PET imaging of GLUT5 in breast cancer.
Nuclear medicine and biology 2011;38(4):461-75.
2009: Brendan J Trayner; Tina N Grant; Frederick G West; Chris I Cheeseman
Synthesis and characterization of 6-deoxy-6-fluoro-D-fructose as a potential compound for imaging breast cancer with PET.
Bioorganic & medicinal chemistry 2009;17(15):5488-95.
2007: Andrei Manolescu; Robert Augustin; Kelle H Moley; Chris I Cheeseman
A highly conserved hydrophobic motif in the exofacial vestibule of fructose transporting SLC2A proteins acts as a critical determinant of their substrate selectivity.
Molecular membrane biology 2007;24(5-6):455-63.
2007: Andrei Manolescu; Kate Witkowska; Adam Kinnaird; Tara Cessford; Chris I Cheeseman
Facilitated hexose transporters: new perspectives on form and function.
Physiology (Bethesda, Md.) 2007;22():234-40.
2006: Chris I Cheeseman; Debbie O'Neill
Isolation of intestinal brush-border membranes.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] 2006;Chapter 3():Unit 3.21.
2006: Chithra Keembiyehetty; Robert Augustin; Mary O Carayannopoulos; Sarah Steer; Andrei Manolescu; Chris I Cheeseman; Kelle H Moley
Mouse glucose transporter 9 splice variants are expressed in adult liver and kidney and are up-regulated in diabetes.
Molecular endocrinology (Baltimore, Md.) 2006;20(3):686-97.
2005: Andrei Manolescu; Alexis M Salas-Burgos; Jorge Fischbarg; Chris I Cheeseman
Identification of a hydrophobic residue as a key determinant of fructose transport by the facilitative hexose transporter SLC2A7 (GLUT7).
The Journal of biological chemistry 2005;280(52):42978-83.
2005: Andrea Scheepers; Stefan Schmidt; Andrei Manolescu; Chris I Cheeseman; Andreas Bell; Claudia Zahn; Hans-Georg Joost; Annette Schürmann
Characterization of the human SLC2A11 (GLUT11) gene: alternative promoter usage, function, expression, and subcellular distribution of three isoforms, and lack of mouse orthologue.
Molecular membrane biology 2005;22(4):339-51.
2005: Qiang Li; Nicolas Montalbetti; Patrick Y Shen; Xiao-Qing Dai; Chris I Cheeseman; Edward Karpinski; Guanqing Wu; Horacio F Cantiello; Xing-Zhen Chen
Alpha-actinin associates with polycystin-2 and regulates its channel activity.
Human molecular genetics 2005;14(12):1587-603.
2004: Qiang Li; Andrei Manolescu; Mabel W L Ritzel; Sylvia Yao; Melissa D Slugoski; James D Young; Xing-Zhen Chen; Chris I Cheeseman
Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(1):G236-42.
2004: Ni T Lam; Anthony T Cheung; Michael J Riedel; Peter E Light; Chris I Cheeseman; Timothy J Kieffer
Leptin reduces glucose transport and cellular ATP levels in INS-1 beta-cells.
Journal of molecular endocrinology 2004;32(2):415-24.
2002: Chris I Cheeseman
Intestinal hexose absorption: transcellular or paracellular fluxes.
The Journal of physiology 2002;544(Pt 2):336.
2002: Anita Au; Alina Gupta; Paul Schembri; Chris I Cheeseman
Rapid insertion of GLUT2 into the rat jejunal brush-border membrane promoted by glucagon-like peptide 2.
The Biochemical journal 2002;367(Pt 1):247-54.
1998: Feng-Qi Zhao; Erasmus Okine; Chris I Cheeseman; S P Shirazi-Beechey; John J Kennelly
Glucose transporter gene expression in lactating bovine gastrointestinal tract.
Journal of animal science 1998;76(11):2921-9.
1998: Chris I Cheeseman; D O'Neill
Basolateral D-glucose transport activity along the crypt-villus axis in rat jejunum and upregulation induced by gastric inhibitory peptide and glucagon-like peptide-2.
Experimental physiology 1998;83(5):605-16.
1998: A J Hirsh; Chris I Cheeseman
Cholecystokinin decreases intestinal hexose absorption by a parallel reduction in SGLT1 abundance in the brush-border membrane.
The Journal of biological chemistry 1998;273(23):14545-9.
1998: Sylvia Y M Yao; WR Muzyka; John Elliott; Chris I Cheeseman; James D Young
Cloning and functional expression of a cDNA from rat jejunal epithelium encoding a protein (4F2hc) with system y+L amino acid transport activity.
The Biochemical journal 1998;330 ( Pt 2)():745-52.
1998: Sylvia Y M Yao; WR Muzyka; Carol E Cass; Chris I Cheeseman; James D Young
Evidence that the transport-related proteins BAT and 4F2hc are not specific for amino acids: induction of Na+-dependent uridine and pyruvate transport activity by recombinant BAT and 4F2hc expressed in Xenopus oocytes.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1998;76(5):859-65.
1997: Chris I Cheeseman
Upregulation of SGLT-1 transport activity in rat jejunum induced by GLP-2 infusion in vivo.
The American journal of physiology 1997;273(6 Pt 2):R1965-71.
1997: A J Hirsh; Sylvia Y M Yao; James D Young; Chris I Cheeseman
Inhibition of glucose absorption in the rat jejunum: a novel action of alpha-D-glucosidase inhibitors.
Gastroenterology 1997;113(1):205-11.
1996: A J Hirsh; R Tsang; S Kammila; Chris I Cheeseman
Effect of cholecystokinin and related peptides on jejunal transepithelial hexose transport in the Sprague-Dawley rat.
The American journal of physiology 1996;271(5 Pt 1):G755-61.
1996: Chris I Cheeseman; R Tsang
The effect of GIP and glucagon-like peptides on intestinal basolateral membrane hexose transport.
The American journal of physiology 1996;271(3 Pt 1):G477-82.
1996: Monika Keelan; Chris I Cheeseman; M Thomas Clandinin; Alan B R Thomson
Intestinal morphology and transport after ileal resection in rat is modified by dietary fatty acids.
Clinical and investigative medicine. Médecine clinique et experimentale 1996;19(2):63-70.
1994: Alan B R Thomson; Chris I Cheeseman; Monika Keelan; R Fedorak; M Thomas Clandinin
Crypt cell production rate, enterocyte turnover time and appearance of transport along the jejunal villus of the rat.
Biochimica et biophysica acta 1994;1191(1):197-204.
1994: R Tsang; Ziliang Ao; Chris I Cheeseman
Influence of vascular and luminal hexoses on rat intestinal basolateral glucose transport.
Canadian journal of physiology and pharmacology 1994;72(4):317-26.
1994: Sylvia Y M Yao; W R Muzyka; John Elliott; Chris I Cheeseman; James D Young
Poly(A)+ RNA from the mucosa of rat jejunum induces novel Na(+)-dependent and Na(+)-independent leucine transport activities in in oocytes of Xenopus laevis.
Molecular membrane biology 1994;11(2):109-18.
1994: Chris I Cheeseman; S Shariff; D O'Neill
Evidence for a lactate-anion exchanger in the rat jejunal basolateral membrane.
Gastroenterology 1994;106(3):559-66.
1993: Chris I Cheeseman
GLUT2 is the transporter for fructose across the rat intestinal basolateral membrane.
Gastroenterology 1993;105(4):1050-6.
1993: C M Harvey; W R Muzyka; Sylvia Y M Yao; Chris I Cheeseman; James D Young
Expression of rat intestinal L-lysine transport systems in isolated oocytes of Xenopus laevis.
The American journal of physiology 1993;265(1 Pt 1):G99-106.
1992: Chris I Cheeseman
Role of intestinal basolateral membrane in absorption of nutrients.
The American journal of physiology 1992;263(3 Pt 2):R482-8.
1992: Bruce K Rubin; Chris I Cheeseman; S Gourishankar; M King
Is there a seasonal variation in mucus transport and nutrient absorption in the leopard frog?
Canadian journal of physiology and pharmacology 1992;70(4):442-6.
1992: Monika Keelan; K Walker; Chris I Cheeseman; Alan B R Thomson
Two weeks of oral synthetic E2 prostaglandin (Enprostil) improves the intestinal morphological but not the absorptive response in the rat to abdominal irradiation.
Digestion 1992;53(1-2):101-7.
1991: Richard N Fedorak; Chris I Cheeseman; Alan B R Thomson; V M Porter
Altered glucose carrier expression: mechanism of intestinal adaptation during streptozocin-induced diabetes in rats.
The American journal of physiology 1991;261(4 Pt 1):G585-91.
1990: C W Lee; Chris I Cheeseman; S M Jarvis
Transport characteristics of renal brush border Na(+)- and K(+)-dependent uridine carriers.
The American journal of physiology 1990;258(5 Pt 2):F1203-10.
1989: Monika Keelan; Alan B R Thomson; M Thomas Clandinin; Michele M Tavernini; K Walker; Chris I Cheeseman
Effect of oral enprostil, a synthetic prostaglandin E2, on intestinal brush border membrane lipid composition following abdominal irradiation in the rat.
Clinical and investigative medicine. Médecine clinique et experimentale 1989;12(6):350-6.
1989: Alan B R Thomson; Monika Keelan; M Thomas Clandinin; Michele M Tavernini; T Lam; K Walker; Chris I Cheeseman
Lack of protective effect of oral enprostil, a synthetic prostaglandin E2, on intestinal transport and morphology following abdominal irradiation in the rat.
Canadian journal of physiology and pharmacology 1989;67(10):1351-6.
1989: Chris I Cheeseman; D D Maenz
Rapid regulation of D-glucose transport in basolateral membrane of rat jejunum.
The American journal of physiology 1989;256(5 Pt 1):G878-83.
1989: Alan B R Thomson; Monika Keelan; T Lam; Chris I Cheeseman; K Walker; M Thomas Clandinin
Saturated fatty acid diet prevents radiation-associated decline in intestinal uptake.
The American journal of physiology 1989;256(1 Pt 1):G178-87.
1988: C W Lee; Chris I Cheeseman; S M Jarvis
Na+- and K+-dependent uridine transport in rat renal brush-border membrane vesicles.
Biochimica et biophysica acta 1988;942(1):139-49.
1988: Alan B R Thomson; Monika Keelan; M Thomas Clandinin; Ray V Rajotte; Chris I Cheeseman; K Walker
Use of polyunsaturated fatty acid diet to treat the enhanced intestinal uptake of lipids in streptozotocin diabetic rats.
Clinical and investigative medicine. Médecine clinique et experimentale 1988;11(1):57-61.
1987: Alan B R Thomson; Monika Keelan; M Thomas Clandinin; Ray V Rajotte; Chris I Cheeseman; K Walker
Treatment of the enhanced intestinal uptake of glucose in diabetic rats with a polyunsaturated fatty acid diet.
Biochimica et biophysica acta 1987;905(2):426-34.
1987: K Lawless; D Maenz; Chris I Cheeseman
Is leucine an allosteric modulator of the lysine transporter in the intestinal basolateral membrane?
The American journal of physiology 1987;253(5 Pt 1):G637-42.
1987: S Davies; D D Maenz; Chris I Cheeseman
A novel imino-acid carrier in the enterocyte basolateral membrane.
Biochimica et biophysica acta 1987;896(2):247-55.
1987: D D Maenz; Chris I Cheeseman
The Na+-independent D-glucose transporter in the enterocyte basolateral membrane: orientation and cytochalasin B binding characteristics.
The Journal of membrane biology 1987;97(3):259-66.
1986: D D Maenz; Chris I Cheeseman
Effect of hyperglycemia on D-glucose transport across the brush-border and basolateral membrane of rat small intestine.
Biochimica et biophysica acta 1986;860(2):277-85.