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Ceshi Chen

Research Profile

Chemicals & Drugs

Anatomy

Disorders

Physiology

Living Beings

Mouse

Procedures

Transplantation, Heterologous

Co-author Network

Publications

TOP 3
Yi Li; Zehua Wang; Junran Zhang; Jing Zhang; Dong Zhao; Zhongmei Zhou; Hui Chen; Wenlin Chen; Xi Chen; Hongmin Li; Ceshi Chen
The HECTD3 E3 ubiquitin ligase suppresses cisplatin-induced apoptosis via stabilizing MALT1.
Xu Zhi; Zhongmei Zhou; Wenlin Chen; Rong Liu; Chunyan Wang; Zehua Wang; Dong Zhao; Ceshi Chen
E3 ubiquitin ligase RNF126 promotes cancer cell proliferation by targeting the tumor suppressor p21 for ubiquitin-mediated degradation.
Xu Zhi; Zhongmei Zhou; Rong Liu; Dong Zhao; Ceshi Chen
YAP promotes breast cell proliferation and survival partially through stabilizing the KLF5 transcription factor.

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All Publications

2013: Yi Li; Zehua Wang; Junran Zhang; Jing Zhang; Dong Zhao; Zhongmei Zhou; Hui Chen; Wenlin Chen; Xi Chen; Hongmin Li; Ceshi Chen
The HECTD3 E3 ubiquitin ligase suppresses cisplatin-induced apoptosis via stabilizing MALT1.
Neoplasia (New York, N.Y.) 2013;15(1):39-48.
2013: Xu Zhi; Zhongmei Zhou; Wenlin Chen; Rong Liu; Chunyan Wang; Zehua Wang; Dong Zhao; Ceshi Chen
E3 ubiquitin ligase RNF126 promotes cancer cell proliferation by targeting the tumor suppressor p21 for ubiquitin-mediated degradation.
Cancer research 2013;73(1):385-94.
2012: Xu Zhi; Zhongmei Zhou; Rong Liu; Dong Zhao; Ceshi Chen
YAP promotes breast cell proliferation and survival partially through stabilizing the KLF5 transcription factor.
The American journal of pathology 2012;180(6):2452-61.
2012: Xu Zhi; Ceshi Chen
WWP1: a versatile ubiquitin E3 ligase in signaling and diseases.
Cellular and molecular life sciences : CMLS 2012;69(9):1425-34.
2012: Kristina Subik; Ping Tang; Chengyu Wu; Brendan Boyce; Ceshi Chen; Di Chen; David Hicks; Qianqian Liang; Linda Schiffhauer; Lei Shu; Lianping Xing
The ubiquitin E3 ligase WWP1 decreases CXCL12-mediated MDA231 breast cancer cell migration and bone metastasis.
Bone 2012;50(4):813-23.
2012: Zhongmei Zhou; Rong Liu; Ceshi Chen
The WWP1 ubiquitin E3 ligase increases TRAIL resistance in breast cancer.
International journal of cancer. Journal international du cancer 2012;130(7):1504-10.
2011: Rong Liu; Dong Zhao; Zhongmei Zhou; Ceshi Chen
The induction of KLF5 transcription factor by progesterone contributes to progesterone-induced breast cancer cell proliferation and dedifferentiation.
Molecular endocrinology (Baltimore, Md.) 2011;25(7):1137-44.
2011: Rong Liu; Zhongmei Zhou; Jian Huang; Ceshi Chen
PMEPA1 promotes androgen receptor-negative prostate cell proliferation through suppressing the Smad3/4-c-Myc-p21 Cip1 signaling pathway.
The Journal of pathology 2011;223(5):683-94.
2010: Jaya Dasgupta; Supriya Kar; Rong Liu; Joy Joseph; Balaraman Kalyanaraman; S James Remington; Ceshi Chen; J Andres Melendez
Reactive oxygen species control senescence-associated matrix metalloproteinase-1 through c-Jun-N-terminal kinase.
Journal of cellular physiology 2010;225(1):52-62.
2010: Dong Zhao; Han-Qiu Zheng; Zhongmei Zhou; Ceshi Chen
The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation.
Cancer research 2010;70(11):4728-38.
2010: Ceshi Chen
Regulation of Krüpple-like factor 5 by targeted protein degradation.
Methods in molecular biology (Clifton, N.J.) 2010;647():267-77.
2009: H-Q Zheng; Z Zhou; J Huang; L Chaudhury; J-T Dong; Ceshi Chen
Krüppel-like factor 5 promotes breast cell proliferation partially through upregulating the transcription of fibroblast growth factor binding protein 1.
Oncogene 2009;28(42):3702-13.
2009: Y Li; Z Zhou; M Alimandi; Ceshi Chen
WW domain containing E3 ubiquitin protein ligase 1 targets the full-length ErbB4 for ubiquitin-mediated degradation in breast cancer.
Oncogene 2009;28(33):2948-58.
2009: Jin-Tang Dong; Ceshi Chen
Essential role of KLF5 transcription factor in cell proliferation and differentiation and its implications for human diseases.
Cellular and molecular life sciences : CMLS 2009;66(16):2691-706.
2009: Rong Liu; Han-Qiu Zheng; Zhongmei Zhou; Jin-Tang Dong; Ceshi Chen
KLF5 promotes breast cell survival partially through fibroblast growth factor-binding protein 1-pERK-mediated dual specificity MKP-1 protein phosphorylation and stabilization.
The Journal of biological chemistry 2009;284(25):16791-8.
2009: Ceshi Chen; Zhongmei Zhou; Christine E Sheehan; Elzbieta Slodkowska; Christopher B Sheehan; Ann Boguniewicz; Jeffrey S Ross
Overexpression of WWP1 is associated with the estrogen receptor and insulin-like growth factor receptor 1 in breast carcinoma.
International journal of cancer. Journal international du cancer 2009;124(12):2829-36.
2008: Y Li; Z Zhou; Ceshi Chen
WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis.
Cell death and differentiation 2008;15(12):1941-51.
2008: Ceshi Chen; Z Zhou; R Liu; Y Li; P B Azmi; A K Seth
The WW domain containing E3 ubiquitin protein ligase 1 upregulates ErbB2 and EGFR through RING finger protein 11.
Oncogene 2008;27(54):6845-55.
2007: Ceshi Chen; Lydia E Matesic
The Nedd4-like family of E3 ubiquitin ligases and cancer.
Cancer metastasis reviews 2007;26(3-4):587-604.
2007: Ceshi Chen; Zhongmei Zhou; Jeffrey S Ross; Wei Zhou; Jin-Tang Dong
The amplified WWP1 gene is a potential molecular target in breast cancer.
International journal of cancer. Journal international du cancer 2007;121(1):80-87.
2007: Ceshi Chen; Xiaodong Sun; Peng Guo; Xue-Yuan Dong; P Sethi; Wei Zhou; Zhongmei Zhou; John Petros; Henry F Frierson; Robert L Vessella; A Atfi; Jin-Tang Dong
Ubiquitin E3 ligase WWP1 as an oncogenic factor in human prostate cancer.
Oncogene 2007;26(16):2386-94.
2007: Ceshi Chen; Zhongmei Zhou; Peng Guo; Jin-Tang Dong
Proteasomal degradation of the KLF5 transcription factor through a ubiquitin-independent pathway.
FEBS letters 2007;581(6):1124-30.
2007: Xiaodong Sun; Yingfa Zhou; Kristen B Otto; Mingrong Wang; Ceshi Chen; Wei Zhou; Krithika Subramanian; Paula M Vertino; Jin-Tang Dong
Infrequent mutation of ATBF1 in human breast cancer.
Journal of cancer research and clinical oncology 2007;133(2):103-5.
2006: Ceshi Chen; Arun K Seth; Andrew E. Aplin
Genetic and expression aberrations of E3 ubiquitin ligases in human breast cancer.
Molecular cancer research : MCR 2006;4(10):695-707.
2006: Xue-Yuan Dong; Ceshi Chen; Xiaodong Sun; Peng Guo; Robert L Vessella; Ruo-Xiang Wang; Leland W K Chung; Wei Zhou; Jin-Tang Dong
FOXO1A is a candidate for the 13q14 tumor suppressor gene inhibiting androgen receptor signaling in prostate cancer.
Cancer research 2006;66(14):6998-7006.
2006: Diansheng Zhong; Aki Morikawa; Lizheng Guo; Cecile G Colpaert; Li Xiong; Aziza Nassar; Ceshi Chen; Neil Lamb; Jin-Tang Dong; Wei Zhou
Homozygous deletion of SMAD4 in breast cancer cell lines and invasive ductal carcinomas.
Cancer biology & therapy 2006;5(6):601-7.
2006: Ningxi Zhu; Lubing Gu; Harry W Findley; Ceshi Chen; Jin-Tang Dong; Lily Yang; Muxiang Zhou
KLF5 Interacts with p53 in regulating survivin expression in acute lymphoblastic leukemia.
The Journal of biological chemistry 2006;281(21):14711-8.
2006: Xiaodong Sun; Ceshi Chen; Robert L Vessella; Jin-Tang Dong
Microsatellite instability and mismatch repair target gene mutations in cell lines and xenografts of prostate cancer.
The Prostate 2006;66(6):660-6.
2006: Ceshi Chen; Michael S Benjamin; Xiaodong Sun; Kristen B Otto; Peng Guo; Xue-Yuan Dong; Yongde Bao; Zhongmei Zhou; Xiaohong Cheng; Jonathan W Simons; Jin-Tang Dong
KLF5 promotes cell proliferation and tumorigenesis through gene regulation and the TSU-Pr1 human bladder cancer cell line.
International journal of cancer. Journal international du cancer 2006;118(6):1346-55.
2005: Ceshi Chen; Xiaodong Sun; Peng Guo; Xue-Yuan Dong; Pooja Sethi; Xiaohong Cheng; Jun Zhou; Junxiu Ling; Jonathan W Simons; Jerry B Lingrel; Jin-Tang Dong
Human Kruppel-like factor 5 is a target of the E3 ubiquitin ligase WWP1 for proteolysis in epithelial cells.
The Journal of biological chemistry 2005;280(50):41553-61.
2005: Ceshi Chen; Xiaodong Sun; Qimei Ran; Keith Wilkinson; Thomas J Murphy; Jonathan W Simons; Jin-Tang Dong
Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and untransformed epithelial cells.
Oncogene 2005;24(20):3319-27.
2005: Xiaodong Sun; Henry F Frierson; Ceshi Chen; Changling Li; Qimei Ran; Kristen B Otto; Brandi L Cantarel; Brandi M Cantarel; Robert L Vessella; Allen C Gao; John Petros; Yutaka Miura; Jonathan W Simons; Jin-Tang Dong
Frequent somatic mutations of the transcription factor ATBF1 in human prostate cancer.
Nature genetics 2005;37(4):407-12.
2004: Ceshi Chen; Yingfa Zhou; Zhongmei Zhou; Xiaodong Sun; Kristen B Otto; Rosalie M Uht; Jin-Tang Dong
Regulation of KLF5 involves the Sp1 transcription factor in human epithelial cells.
Gene 2004;330():133-42.
2003: Ceshi Chen; Hina V Bhalala; Robert L Vessella; Jin-Tang Dong
KLF5 is frequently deleted and down-regulated but rarely mutated in prostate cancer.
The Prostate 2003;55(2):81-8.
2003: Ceshi Chen; Eija-Riitta Hyytinen; Xiaodong Sun; Heikki Helin; Pasi A Koivisto; Henry F Frierson; Robert L Vessella; Jin-Tang Dong
Deletion, mutation, and loss of expression of KLF6 in human prostate cancer.
The American journal of pathology 2003;162(4):1349-54.
2002: Ceshi Chen; Hina V Bhalala; Hui Qiao; Jin-Tang Dong
A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer.
Oncogene 2002;21(43):6567-72.
2002: Eija-Riitta Hyytinen; Rega Saadut; Ceshi Chen; Lindsay Paull; Pasi A Koivisto; Robert L Vessella; Henry F Frierson; Jin-Tang Dong
Defining the region(s) of deletion at 6q16-q22 in human prostate cancer.
Genes, chromosomes & cancer 2002;34(3):306-12.
2001: Ceshi Chen; Henry F Frierson; P F Haggerty; Dan Theodorescu; C W Gregory; Jin-Tang Dong
An 800-kb region of deletion at 13q14 in human prostate and other carcinomas.
Genomics 2001;77(3):135-44.
2001: Ceshi Chen; W W Brabham; B G Stultz; Henry F Frierson; J C Barrett; C L Sawyers; John T Isaacs; Jin-Tang Dong
Defining a common region of deletion at 13q21 in human cancers.
Genes, chromosomes & cancer 2001;31(4):333-44.
2000: F Chen; Ceshi Chen; Y Li; G Yin
[Studies on gene knocking out of 2-keto aldose reductases from Erwinia sp. SCB125].
Wei sheng wu xue bao = Acta microbiologica Sinica 2000;40(5):475-81.
2000: Jin-Tang Dong; Ceshi Chen; B G Stultz; John T Isaacs; Henry F Frierson
Deletion at 13q21 is associated with aggressive prostate cancers.
Cancer research 2000;60(14):3880-3.
2000: M Li; Ceshi Chen; D Wang
[Gene cloning and expression of prolyl endopeptidase from Aeromonas punctata].
Wei sheng wu xue bao = Acta microbiologica Sinica 2000;40(3):277-83.
1998: Ceshi Chen; G Yin
[Cloning and expression in E. coli of 2,5-DKG reductase I from Corynebacterium].
Wei sheng wu xue bao = Acta microbiologica Sinica 1998;38(6):435-40.
1998: M Li; Ceshi Chen; Q Pu; S Chen
Production of human recombinant bone morphogenetic protein-2A by high density culture of Escherichia coli with stationary dissolved oxygen fed-batch condition.
Chinese journal of biotechnology 1998;14(3):157-63.
1998: H Xu; C Gao; H Liu; F Deng; H Pan; Ceshi Chen
Downstream technique study of human tumor necrosis factor alpha and its mutant.
Chinese journal of biotechnology 1998;14(2):109-15.
1997: L Pan; J Chen; Ceshi Chen
Cloning and sequence analysis of the 5'-flanking region of goat beta-lactoglobulin gene.
Chinese journal of biotechnology 1997;13(2):79-83.