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Guang Chen

Research Profile

Disorders

Bipolar Disorder

Chemicals & Drugs

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TOP 3
Oz Malkesman; Husseini K Manji; Kazu Nakazawa; Gregory Rompala; Tyson Tragon; Gang Wang; W Scott Young; Carlos A Zarate; Daniel R Austin; Zhenzhong Cui; Anahita B Hamidi; Guang Chen
Acute D-serine treatment produces antidepressant-like effects in rodents.
Oz Malkesman; D R Austin; Guang Chen; Ioline D Henter; M Pellecchia; J C Reed; T Tragon; Husseini K Manji
Targeting the BH3-interacting domain death agonist to develop mechanistically unique antidepressants.
Dhaval Nanavati; Daniel R Austin; Lisa A Catapano; Guang Chen; Ayse Dosemeci; David Luckenbaugh; Husseini K Manji; Sanford P Markey
The effects of chronic treatment with mood stabilizers on the rat hippocampal post-synaptic density proteome.

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All Publications

2012: Oz Malkesman; Husseini K Manji; Kazu Nakazawa; Gregory Rompala; Tyson Tragon; Gang Wang; W Scott Young; Carlos A Zarate; Daniel R Austin; Zhenzhong Cui; Anahita B Hamidi; Guang Chen
Acute D-serine treatment produces antidepressant-like effects in rodents.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2012;15(8):1135-48.
2012: Oz Malkesman; D R Austin; Guang Chen; Ioline D Henter; M Pellecchia; J C Reed; T Tragon; Husseini K Manji
Targeting the BH3-interacting domain death agonist to develop mechanistically unique antidepressants.
Molecular psychiatry 2012;17(8):770-80.
2011: Dhaval Nanavati; Daniel R Austin; Lisa A Catapano; Guang Chen; Ayse Dosemeci; David Luckenbaugh; Husseini K Manji; Sanford P Markey
The effects of chronic treatment with mood stabilizers on the rat hippocampal post-synaptic density proteome.
Journal of neurochemistry 2011;119(3):617-29.
2011: Joshua G Hunsberger; Rodrigo Machado-Vieira; Daniel R Austin; Guang Chen; De-Maw Chuang; John C Reed; Carlos Zarate; Husseini K Manji
Bax inhibitor 1, a modulator of calcium homeostasis, confers affective resilience.
Brain research 2011;1403():19-27.
2011: Thomas K Creson; Husseini K Manji; Joseph McCammon; Galit Shaltiel; Jürgen Wess; Daniel R Austin; Guang Chen
Lithium treatment attenuates muscarinic M(1) receptor dysfunction.
Bipolar disorders 2011;13(3):238-49.
2011: Peixiong Yuan; Tyson Tragon; Menghang Xia; Christopher A Leclair; Amanda P Skoumbourdis; Wei Zheng; Craig J Thomas; Ruili Huang; Christopher P Austin; Guang Chen; Xavier Guitart
Phosphodiesterase 4 inhibitors enhance sexual pleasure-seeking activity in rodents.
Pharmacology, biochemistry, and behavior 2011;98(3):349-55.
2011: Rodrigo Machado-Vieira; Natalia B Pivovarova; Ruslan I Stanika; Peixiong Yuan; Yun Wang; Rulun Zhou; Carlos A Zarate; Wayne C Drevets; Christine A Brantner; Amber Baum; Gonzalo Laje; Francis McMajon; Guang Chen; Jing Du; Husseini K Manji; S Brian Andrews
The Bcl-2 gene polymorphism rs956572AA increases inositol 1,4,5-trisphosphate receptor-mediated endoplasmic reticulum calcium release in subjects with bipolar disorder.
Biological psychiatry 2011;69(4):344-52.
2010: Guang Chen; Ioline D Henter; Husseini K Manji
Translational research in bipolar disorder: emerging insights from genetically based models.
Molecular psychiatry 2010;15(9):883-95.
2010: Peixiong Yuan; Rulun Zhou; Yun Wang; Xiaoxia Li; Jianling Li; Guang Chen; Xavier Guitart; Husseini K Manji
Altered levels of extracellular signal-regulated kinase signaling proteins in postmortem frontal cortex of individuals with mood disorders and schizophrenia.
Journal of affective disorders 2010;124(1-2):164-9.
2010: Guang Chen; Ioline D Henter; Husseini K Manji
Presynaptic glutamatergic dysfunction in bipolar disorder.
Biological psychiatry 2010;67(11):1007-9.
2010: Oz Malkesman; Maria Luisa Scattoni; Daniel Paredes; Tyson Tragon; Brandon Pearson; Galit Shaltiel; Guang Chen; Jacqueline N Crawley; Husseini K Manji
The female urine sniffing test: a novel approach for assessing reward-seeking behavior in rodents.
Biological psychiatry 2010;67(9):864-71.
2009: Rulun Zhou; Andrew Holmes; Jing Du; Oz Malkesman; Peixiong Yuan; Yun Wang; Patricia Damschroder-Williams; Guang Chen; Xavier Guitart; Husseini K Manji
Genome-wide gene expression profiling in GluR1 knockout mice: key role of the calcium signaling pathway in glutamatergically mediated hippocampal transmission.
The European journal of neuroscience 2009;30(12):2318-26.
2009: Guang Chen; Ioline D Henter; Husseini K Manji
A role for PKC in mediating stress-induced prefrontal cortical structural plasticity and cognitive function.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(42):17613-4.
2009: Giacomo Salvadore; Allison C Nugent; Guang Chen; Nirmala Akula; Peixiong Yuan; Dara M Cannon; Carlos A Zarate; Francis McMajon; Husseini K Manji; Wayne C Drevets
Bcl-2 polymorphism influences gray matter volume in the ventral striatum in healthy humans.
Biological psychiatry 2009;66(8):804-7.
2009: Joshua G Hunsberger; Daniel R Austin; Guang Chen; Husseini K Manji
Cellular mechanisms underlying affective resiliency: the role of glucocorticoid receptor- and mitochondrially-mediated plasticity.
Brain research 2009;1293():76-84.
2009: Thomas K Creson; Yanlei Hao; Sharon Engel; Yi Shen; Anahita Hamidi; Min Zhuo; Husseini K Manji; Guang Chen
The anterior cingulate ERK pathway contributes to regulation of behavioral excitement and hedonic activity.
Bipolar disorders 2009;11(4):339-50.
2009: Peixiong Yuan; Giacomo Salvadore; Xiaoxia Li; Lei Zhang; Jing Du; Guang Chen; Husseini K Manji
Valproate activates the Notch3/c-FLIP signaling cascade: a strategy to attenuate white matter hyperintensities in bipolar disorder in late life?
Bipolar disorders 2009;11(3):256-69.
2009: Oz Malkesman; Daniel R Austin; Guang Chen; Husseini K Manji
Reverse translational strategies for developing animal models of bipolar disorder.
Disease models & mechanisms 2009;2(5-6):238-45.
2009: Rulun Zhou; Peixiong Yuan; Yun Wang; Joshua G Hunsberger; Abdel Elkahloun; Yanling Wei; Patricia Damschroder-Williams; Jing Du; Guang Chen; Husseini K Manji
Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(6):1395-405.
2009: Oz Malkesman; Daniel S Pine; Tyson Tragon; Daniel R Austin; Ioline D Henter; Guang Chen; Husseini K Manji
Animal models of suicide-trait-related behaviors.
Trends in pharmacological sciences 2009;30(4):165-73.
2009: S R Engel; T K Creson; Y Hao; Yong Shen; Sungho Maeng; T Nekrasova; Gary Landreth; Husseini K Manji; Guang Chen
The extracellular signal-regulated kinase pathway contributes to the control of behavioral excitement.
Molecular psychiatry 2009;14(4):448-61.
2009: Joshua Hunsberger; Daniel R Austin; Ioline D Henter; Guang Chen
The neurotrophic and neuroprotective effects of psychotropic agents.
Dialogues in clinical neuroscience 2009;11(3):333-48.
2009: Joshua G Hunsberger; Daniel R Austin; Guang Chen; Husseini K Manji
MicroRNAs in mental health: from biological underpinnings to potential therapies.
Neuromolecular medicine 2009;11(3):173-82.
2008: G Shaltiel; Sungho Maeng; O Malkesman; Brandon Pearson; Robert Schloesser; T Tragon; Michael A Rogawski; M Gasior; David Luckenbaugh; Guang Chen; Husseini K Manji
Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania.
Molecular psychiatry 2008;13(9):858-72.
2008: Lukas Pezawas; Andreas Meyer-Lindenberg; A L Goldman; Beth A Verchinski; Guang Chen; Bhaskar S Kolachana; Michael Egan; Venkata S Mattay; Ahmad R Hariri; Daniel R Weinberger
Evidence of biologic epistasis between BDNF and SLC6A4 and implications for depression.
Molecular psychiatry 2008;13(7):709-16.
2008: Sungho Maeng; Joshua G Hunsberger; Brandon Pearson; Peixiong Yuan; Yun Wang; Yanling Wei; Joseph McCammon; Robert Schloesser; Rulun Zhou; Jing Du; Guang Chen; Bruce McEwen; John C Reed; Husseini K Manji
BAG1 plays a critical role in regulating recovery from both manic-like and depression-like behavioral impairments.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(25):8766-71.
2008: Martin J Lan; Peixiong Yuan; Guang Chen; Husseini K Manji
Neuronal peroxisome proliferator-activated receptor gamma signaling: regulation by mood-stabilizer valproate.
Journal of molecular neuroscience : MN 2008;35(2):225-34.
2008: Todd D Gould; Kelley C O'Donnell; Alyssa M Picchini; Eliot R Dow; Guang Chen; Husseini K Manji
Generation and behavioral characterization of beta-catenin forebrain-specific conditional knock-out mice.
Behavioural brain research 2008;189(1):117-25.
2008: Todd D Gould; Kelley C O'Donnell; Eliot R Dow; Jing Du; Guang Chen; Husseini K Manji
Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test.
Neuropharmacology 2008;54(3):577-87.
2008: Sungho Maeng; Carlos A Zarate; Jing Du; Robert Schloesser; Joseph McCammon; Guang Chen; Husseini K Manji
Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors.
Biological psychiatry 2008;63(4):349-52.
2008: Jing Du; Thomas K Creson; Long-Jun Wu; Ming Ren; Neil A Gray; Cynthia Falke; Yanling Wei; Yun Wang; Rayah Blumenthal; Rodrigo Machado-Vieira; Peixiong Yuan; Guang Chen; Min Zhuo; Husseini K Manji
The role of hippocampal GluR1 and GluR2 receptors in manic-like behavior.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(1):68-79.
2007: Todd D Gould; Eliot R Dow; Kelley C O'Donnell; Guang Chen; Husseini K Manji
Targeting signal transduction pathways in the treatment of mood disorders: recent insights into the relevance of the Wnt pathway.
CNS & neurological disorders drug targets 2007;6(3):193-204.
2007: Galit Shaltiel; Guang Chen; Husseini K Manji
Neurotrophic signaling cascades in the pathophysiology and treatment of bipolar disorder.
Current opinion in pharmacology 2007;7(1):22-6.
2007: Robert Schloesser; Guang Chen; Husseini K Manji
Neurogenesis and neuroenhancement in the pathophysiology and treatment of bipolar disorder.
International review of neurobiology 2007;77():143-78.
2006: Guang Chen; Husseini K Manji
The extracellular signal-regulated kinase pathway: an emerging promising target for mood stabilizers.
Current opinion in psychiatry 2006;19(3):313-23.
2005: Rulun Zhou; Neil A Gray; Peixiong Yuan; Xiaoxia Li; Jingshan Chen; Guang Chen; Patricia Damschroder-Williams; Jing Du; Lei Zhang; Husseini K Manji
The anti-apoptotic, glucocorticoid receptor cochaperone protein BAG-1 is a long-term target for the actions of mood stabilizers.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(18):4493-502.
2004: Yanlei Hao; Thomas Creson; Lei Zhang; Pipeng Li; Fu Du; Peixiong Yuan; Todd D Gould; Husseini K Manji; Guang Chen
Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(29):6590-9.
2004: Haim Einat; Guang Chen; Husseini K Manji
[Possible involvement of protein kinase C in the pathophysiology and treatment of bipolar disorder].
Harefuah 2004;143(6):420-5, 462.
2004: Yanlei Hao; Anthony Basile; Guang Chen; Lei Zhang
Glutamate-induced over-expression of GAD is down-regulated by acetyl-L-carnitine in rat islet cells.
Endocrine research 2004;30(1):107-16.
2004: Todd D Gould; Guang Chen; Husseini K Manji
In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2004;29(1):32-8.
2003: Haim Einat; Husseini K Manji; Todd D Gould; Jing Du; Guang Chen
Possible involvement of the ERK signaling cascade in bipolar disorder: behavioral leads from the study of mutant mice.
Drug news & perspectives 2003;16(7):453-63.
2003: Haim Einat; Peixiong Yuan; Todd D Gould; Jianling Li; JianHua Du; Lei Zhang; Husseini K Manji; Guang Chen
The role of the extracellular signal-regulated kinase signaling pathway in mood modulation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(19):7311-6.
2003: Jianling Li; Todd D Gould; Peixiong Yuan; Husseini K Manji; Guang Chen
Post-mortem interval effects on the phosphorylation of signaling proteins.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(6):1017-25.
2003: Xizhong Huang; Da-Yu Wu; Guang Chen; Husseini K Manji; Dong Feng Chen
Support of retinal ganglion cell survival and axon regeneration by lithium through a Bcl-2-dependent mechanism.
Investigative ophthalmology & visual science 2003;44(1):347-54.
2002: Husseini K Manji; Guang Chen
PKC, MAP kinases and the bcl-2 family of proteins as long-term targets for mood stabilizers.
Molecular psychiatry 2002;7 Suppl 1():S46-56.
2001: PX Yuan; LD Huang; YM Jiang; J Silvio Gutkind; Husseini K Manji; Guang Chen
The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth.
The Journal of biological chemistry 2001;276(34):31674-83.
2001: Husseini K Manji; Gregory Moore; Guang Chen
Bipolar disorder: leads from the molecular and cellular mechanisms of action of mood stabilizers.
The British journal of psychiatry. Supplement 2001;41():s107-19.
2001: Guang Chen; LD Huang; W Z Zeng; H K Manji
Mood stabilizers regulate cytoprotective and mRNA-binding proteins in the brain: long-term effects on cell survival and transcript stability.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2001;4(1):47-64.
2000: Husseini K Manji; Guang Chen
Post-receptor signaling pathways in the pathophysiology and treatment of mood disorders.
Current psychiatry reports 2000;2(6):479-89.
2000: Husseini K Manji; Gregory Moore; G Rajkowska; Guang Chen
Neuroplasticity and cellular resilience in mood disorders.
Molecular psychiatry 2000;5(6):578-93.
2000: Husseini K Manji; Gregory Moore; Guang Chen
Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic-depressive illness.
Biological psychiatry 2000;48(8):740-54.
2000: Gregory Moore; JM Bebchuk; Ian B Wilds; Guang Chen; Husseini K Manji; H K Menji
Lithium-induced increase in human brain grey matter.
Lancet 2000;356(9237):1241-2.
2000: Guang Chen; G Rajkowska; F Du; Navid Seraji-Bozorgzad; Husseini K Manji
Enhancement of hippocampal neurogenesis by lithium.
Journal of neurochemistry 2000;75(4):1729-34.
2000: Guang Chen; M I Masana; Husseini K Manji
Lithium regulates PKC-mediated intracellular cross-talk and gene expression in the CNS in vivo.
Bipolar disorders 2000;2(3 Pt 2):217-36.
2000: Jair C Soares; Guang Chen; CS Dippold; Kelly Forster Wells; Ellen Frank; David J Kupfer; Husseini K Manji; ALAN MALLINGER
Concurrent measures of protein kinase C and phosphoinositides in lithium-treated bipolar patients and healthy individuals: a preliminary study.
Psychiatry research 2000;95(2):109-18.
2000: Gregory Moore; JM Bebchuk; KA Hasanat; Guang Chen; Navid Seraji-Bozorgzad; Ian B Wilds; Michael W Faulk; S Koch; Debra Glitz; Libby Jolkovsky; Husseini K Manji
Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2's neurotrophic effects?
Biological psychiatry 2000;48(1):1-8.
2000: Husseini K Manji; Gregory Moore; Guang Chen
Lithium up-regulates the cytoprotective protein Bcl-2 in the CNS in vivo: a role for neurotrophic and neuroprotective effects in manic depressive illness.
The Journal of clinical psychiatry 2000;61 Suppl 9():82-96.
1999: Husseini K Manji; R McNamara; Guang Chen; RH Lenox
Signalling pathways in the brain: cellular transduction of mood stabilisation in the treatment of manic-depressive illness.
The Australian and New Zealand journal of psychiatry 1999;33 Suppl():S65-83.
1999: Peixiong Yuan; Guang Chen; Husseini K Manji
Lithium activates the c-Jun NH2-terminal kinases in vitro and in the CNS in vivo.
Journal of neurochemistry 1999;73(6):2299-309.
1999: Husseini K Manji; Gregory Moore; Guang Chen
Lithium at 50: have the neuroprotective effects of this unique cation been overlooked?
Biological psychiatry 1999;46(7):929-40.
1999: Guang Chen; KA Hasanat; JM Bebchuk; Gregory Moore; Debra Glitz; Husseini K Manji
Regulation of signal transduction pathways and gene expression by mood stabilizers and antidepressants.
Psychosomatic medicine 1999;61(5):599-617.
1999: Guang Chen; LD Huang; YM Jiang; Husseini K Manji
The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3.
Journal of neurochemistry 1999;72(3):1327-30.
1999: Guang Chen; W Z Zeng; PX Yuan; LD Huang; YM Jiang; Z H Zhao; Husseini K Manji
The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS.
Journal of neurochemistry 1999;72(2):879-82.
1999: Guang Chen; PX Yuan; YM Jiang; LD Huang; Husseini K Manji
Valproate robustly enhances AP-1 mediated gene expression.
Brain research. Molecular brain research 1999;64(1):52-8.
1999: Husseini K Manji; JM Bebchuk; Gregory Moore; Debra Glitz; KA Hasanat; Guang Chen
Modulation of CNS signal transduction pathways and gene expression by mood-stabilizing agents: therapeutic implications.
The Journal of clinical psychiatry 1999;60 Suppl 2():27-39; discussion 40-1, 113-6.
1998: PX Yuan; Guang Chen; LD Huang; Husseini K Manji
Lithium stimulates gene expression through the AP-1 transcription factor pathway.
Brain research. Molecular brain research 1998;58(1-2):225-30.
1998: Guang Chen; PX Yuan; YM Jiang; LD Huang; Husseini K Manji
Lithium increases tyrosine hydroxylase levels both in vivo and in vitro.
Journal of neurochemistry 1998;70(4):1768-71.
1997: Guang Chen; Peixiong Yuan; D B Hawver; W Z Potter; Husseini K Manji
Increase in AP-1 transcription factor DNA binding activity by valproic acid.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1997;16(3):238-45.
1997: P B Mitchell; Husseini K Manji; Guang Chen; Libby Jolkovsky; E Smith-Jackson; Kirk D Denicoff; M Schmidt; W Z Potter
High levels of Gs alpha in platelets of euthymic patients with bipolar affective disorder.
The American journal of psychiatry 1997;154(2):218-23.
1997: Husseini K Manji; Guang Chen; W Potter; Thomas R Kosten
Guanine nucleotide binding proteins in opioid-dependent patients.
Biological psychiatry 1997;41(2):130-4.
1996: Guang Chen; B Pan; D B Hawver; Clinton Wright; William Z Potter; Husseini K Manji
Attenuation of cyclic AMP production by carbamazepine.
Journal of neurochemistry 1996;67(5):2079-86.
1996: Husseini K Manji; Y Bersudsky; Guang Chen; R H Belmaker; William Z Potter
Modulation of protein kinase C isozymes and substrates by lithium: the role of myo-inositol.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1996;15(4):370-81.
1996: Guang Chen; Husseini K Manji; Clinton Wright; D B Hawver; William Z Potter
Effects of valproic acid on beta-adrenergic receptors, G-proteins, and adenylyl cyclase in rat C6 glioma cells.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1996;15(3):271-80.
1996: Murray B Stein; Guang Chen; W Z Potter; Husseini K Manji
G-protein level quantification in platelets and leukocytes from patients with panic disorder.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1996;15(2):180-6.
1996: Husseini K Manji; Guang Chen; J K Hsiao; E D Risby; M I Masana; William Z Potter
Regulation of signal transduction pathways by mood-stabilizing agents: implications for the delayed onset of therapeutic efficacy.
The Journal of clinical psychiatry 1996;57 Suppl 13():34-46; discussion 47-8.
1995: K Suyama; K Saito; Guang Chen; B S Pan; Husseini K Manji; William Z Potter
Alterations in cyclic AMP generation and G protein subunits following transient ischemia in gerbil hippocampus.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1995;15(5):877-85.
1995: Husseini K Manji; Guang Chen; H Shimon; J K Hsiao; William Z Potter; R H Belmaker
Guanine nucleotide-binding proteins in bipolar affective disorder. Effects of long-term lithium treatment.
Archives of general psychiatry 1995;52(2):135-44.
1995: I W Chung; Y S Kim; J S Ahn; H S Lee; Guang Chen; Husseini K Manji; W Z Potter; DAVID PICKAR
Pharmacologic profile of natural products used to treat psychotic illnesses.
Psychopharmacology bulletin 1995;31(1):139-45.
1994: Guang Chen; Husseini K Manji; D B Hawver; Clinton Wright; William Z Potter
Chronic sodium valproate selectively decreases protein kinase C alpha and epsilon in vitro.
Journal of neurochemistry 1994;63(6):2361-4.
1993: Husseini K Manji; René Etcheberrigaray; Guang Chen; J L Olds
Lithium decreases membrane-associated protein kinase C in hippocampus: selectivity for the alpha isozyme.
Journal of neurochemistry 1993;61(6):2303-10.
1993: S E Molchan; Husseini K Manji; Guang Chen; L Dou; John Timothy Little; W Z Potter; Trey Sunderland
Effects of chronic lithium treatment on platelet PKC isozymes in Alzheimer's and elderly control subjects.
Neuroscience letters 1993;162(1-2):187-91.
1992: Husseini K Manji; Guang Chen; JOSE BITRAN; F Gusovsky; William Z Potter
Idazoxan down-regulates beta-adrenoceptors on C6 glioma cells in vitro.
European journal of pharmacology 1992;227(3):275-82.
1992: J K Hsiao; Husseini K Manji; Guang Chen; J A Bitran; E D Risby; William Z Potter
Lithium administration modulates platelet Gi in humans.
Life sciences 1992;50(3):227-33.
1992: Husseini K Manji; E D Risby; J K Hsiao; Guang Chen; William Z Potter
Effects of lithium on signal transduction in humans.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():608A-609A.
1991: Husseini K Manji; Guang Chen; J A Bitran; F Gusovsky; William Z Potter
Chronic exposure of C6 glioma cells to desipramine desensitizes beta-adrenoceptors, but increases KL/KH ratio.
European journal of pharmacology 1991;206(2):159-62.
1991: Husseini K Manji; J A Bitran; M I Masana; Guang Chen; J K Hsiao; E D Risby; M V Rudorfer; William Z Potter
Signal transduction modulation by lithium: cell culture, cerebral microdialysis and human studies.
Psychopharmacology bulletin 1991;27(3):199-208.
1991: Husseini K Manji; Guang Chen; J A Bitran; William Z Potter
Down-regulation of beta receptors by desipramine in vitro involves PKC/phospholipase A2.
Psychopharmacology bulletin 1991;27(3):247-53.