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Edson Albuquerque

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Edson X Albuquerque; Robert Schwarcz
Kynurenic acid as an antagonist of α7 nicotinic acetylcholine receptors in the brain: facts and challenges.
Jyotirmoy Banerjee; Manickavasagom Alkondon; Edson X Albuquerque
Kynurenic acid inhibits glutamatergic transmission to CA1 pyramidal neurons via α7 nAChR-dependent and -independent mechanisms.
Jyotirmoy Banerjee; Edna F R Pereira; Manickavasagom Alkondon; Edson X Albuquerque
Regulation of GABAergic inputs to CA1 pyramidal neurons by nicotinic receptors and kynurenic acid.

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All Publications

2013: Edson X Albuquerque; Robert Schwarcz
Kynurenic acid as an antagonist of α7 nicotinic acetylcholine receptors in the brain: facts and challenges.
Biochemical pharmacology 2013;85(8):1027-32.
2012: Jyotirmoy Banerjee; Manickavasagom Alkondon; Edson X Albuquerque
Kynurenic acid inhibits glutamatergic transmission to CA1 pyramidal neurons via α7 nAChR-dependent and -independent mechanisms.
Biochemical pharmacology 2012;84(8):1078-87.
2012: Jyotirmoy Banerjee; Edna F R Pereira; Manickavasagom Alkondon; Edson X Albuquerque
Regulation of GABAergic inputs to CA1 pyramidal neurons by nicotinic receptors and kynurenic acid.
The Journal of pharmacology and experimental therapeutics 2012;341(2):500-9.
2011: Jacek A Mamczarz; Edna F R Pereira; Girish S Kulkarni; Edson X Albuquerque
Galantamine counteracts development of learning impairment in guinea pigs exposed to the organophosphorus poison soman: clinical significance.
Neurotoxicology 2011;32(6):785-98.
2011: Manickavasagom Alkondon; Edna F R Pereira; Edson X Albuquerque
Endogenous activation of nAChRs and NMDA receptors contributes to the excitability of CA1 stratum radiatum interneurons in rat hippocampal slices: effects of kynurenic acid.
Biochemical pharmacology 2011;82(8):842-51.
2011: Manickavasagom Alkondon; Edna F R Pereira; Howard M Eisenberg; YASUSHI KAJII; Robert Schwarcz; Edson X Albuquerque
Age dependency of inhibition of alpha7 nicotinic receptors and tonically active N-methyl-D-aspartate receptors by endogenously produced kynurenic acid in the brain.
The Journal of pharmacology and experimental therapeutics 2011;337(3):572-82.
2010: Jürgen Ludwig; Anja Höffle-Maas; Marek Samochocki; Edgar Luttmann; Edson X Albuquerque; Gregor Fels; Alfred Maelicke
Localization by site-directed mutagenesis of a galantamine binding site on α7 nicotinic acetylcholine receptor extracellular domain.
Journal of receptor and signal transduction research 2010;30(6):469-83.
2010: Elena A Alexandrova; Yasco Aracava; Edna F R Pereira; Edson X Albuquerque
Pretreatment of Guinea pigs with galantamine prevents immediate and delayed effects of soman on inhibitory synaptic transmission in the hippocampus.
The Journal of pharmacology and experimental therapeutics 2010;334(3):1051-8.
2010: Michelle C Potter; Gregory I Elmer; Richard Bergeron; Edson X Albuquerque; Paolo Guidetti; Hui-Qiu Wu; Robert Schwarcz
Reduction of endogenous kynurenic acid formation enhances extracellular glutamate, hippocampal plasticity, and cognitive behavior.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010;35(8):1734-42.
2010: Jacek A Mamczarz; Edna F R Pereira; Yasco Aracava; Michael Adler; Edson X Albuquerque
An acute exposure to a sub-lethal dose of soman triggers anxiety-related behavior in guinea pigs: interactions with acute restraint.
Neurotoxicology 2010;31(1):77-84.
2010: Rao P Gullapalli; Yasco Aracava; Jiachen Zhuo; Edward Helal Neto; Jiazheng Wang; George Makris; Istvan Merchenthaler; Edna F R Pereira; Edson X Albuquerque
Magnetic resonance imaging reveals that galantamine prevents structural brain damage induced by an acute exposure of guinea pigs to soman.
Neurotoxicology 2010;31(1):67-76.
2010: Edna F R Pereira; Yasco Aracava; Manickavasagom Alkondon; Miriam Akkerman; Istvan Merchenthaler; Edson X Albuquerque
Molecular and cellular actions of galantamine: clinical implications for treatment of organophosphorus poisoning.
Journal of molecular neuroscience : MN 2010;40(1-2):196-203.
2010: Hui-Qiu Wu; Edna F R Pereira; John P Bruno; Roberto Pellicciari; Edson X Albuquerque; Robert Schwarcz
The astrocyte-derived alpha7 nicotinic receptor antagonist kynurenic acid controls extracellular glutamate levels in the prefrontal cortex.
Journal of molecular neuroscience : MN 2010;40(1-2):204-10.
2009: Yasco Aracava; Edna F R Pereira; Miriam Akkerman; Michael Adler; Edson X Albuquerque
Effectiveness of donepezil, rivastigmine, and (+/-)huperzine A in counteracting the acute toxicity of organophosphorus nerve agents: comparison with galantamine.
The Journal of pharmacology and experimental therapeutics 2009;331(3):1014-24.
2009: William P Fawcett; Yasco Aracava; Michael Adler; Edna F R Pereira; Edson X Albuquerque
Acute toxicity of organophosphorus compounds in guinea pigs is sex- and age-dependent and cannot be solely accounted for by acetylcholinesterase inhibition.
The Journal of pharmacology and experimental therapeutics 2009;328(2):516-24.
2009: Edson X Albuquerque; Edna F R Pereira; Manickavasagom Alkondon; Scott W Rogers
Mammalian nicotinic acetylcholine receptors: from structure to function.
Physiological reviews 2009;89(1):73-120.
2009: Manickavasagom Alkondon; Yasco Aracava; Edna F R Pereira; Edson X Albuquerque
A single in vivo application of cholinesterase inhibitors has neuron type-specific effects on nicotinic receptor activity in guinea pig hippocampus.
The Journal of pharmacology and experimental therapeutics 2009;328(1):69-82.
2007: Manickavasagom Alkondon; Edna F R Pereira; Edson X Albuquerque
Age-dependent changes in the functional expression of two nicotinic receptor subtypes in CA1 stratum radiatum interneurons in the rat hippocampus.
Biochemical pharmacology 2007;74(8):1134-44.
2007: Cristiane Lopes; Edna F R Pereira; Hui-Qiu Wu; Puranik Purushottamachar; Vincent Njar; Robert Schwarcz; Edson X Albuquerque
Competitive antagonism between the nicotinic allosteric potentiating ligand galantamine and kynurenic acid at alpha7* nicotinic receptors.
The Journal of pharmacology and experimental therapeutics 2007;322(1):48-58.
2007: Manickavasagom Alkondon; Edna F R Pereira; Michelle C Potter; Frederick C Kauffman; Robert Schwarcz; Edson X Albuquerque
Strain-specific nicotinic modulation of glutamatergic transmission in the CA1 field of the rat hippocampus: August Copenhagen Irish versus Sprague-Dawley.
Journal of neurophysiology 2007;97(2):1163-70.
2007: Paolo Guidetti; Gloria E Hoffman; Miguel Melendez-Ferro; Edson X Albuquerque; Robert Schwarcz
Astrocytic localization of kynurenine aminotransferase II in the rat brain visualized by immunocytochemistry.
Glia 2007;55(1):78-92.
2006: Hélio R Santos; Helizane S Ribeiro; Pedro Setti-Perdigão; Edson X Albuquerque; Newton G Castro
The magnitude of alpha7 nicotinic receptor currents in rat hippocampal neurons is dependent upon GABAergic activity and depolarization.
The Journal of pharmacology and experimental therapeutics 2006;319(1):376-85.
2006: Edson X Albuquerque; Edna F R Pereira; Yasco Aracava; William P Fawcett; Maristela Oliveira; William R Randall; Tracey A Hamilton; Robert K Kan; James A Romano; Michael Adler
Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(35):13220-5.
2006: Manickavasagom Alkondon; Edson X Albuquerque
Subtype-specific inhibition of nicotinic acetylcholine receptors by choline: a regulatory pathway.
The Journal of pharmacology and experimental therapeutics 2006;318(1):268-75.
2006: Rodica V Popa; Edna F R Pereira; Cristiane Lopes; Alfred Maelicke; Edson X Albuquerque
The N-butylcarbamate derivative of galantamine acts as an allosteric potentiating ligand on alpha7 nicotinic receptors in hippocampal neurons: clinical implications for treatment of Alzheimer's disease.
Journal of molecular neuroscience : MN 2006;30(1-2):227-32.
2005: Manickavasagom Alkondon; Edson X Albuquerque
Nicotinic receptor subtypes in rat hippocampal slices are differentially sensitive to desensitization and early in vivo functional up-regulation by nicotine and to block by bupropion.
The Journal of pharmacology and experimental therapeutics 2005;313(2):740-50.
2005: Arash Rassoulpour; Hui-Qiu Wu; Edson X Albuquerque; Robert Schwarcz
Prolonged nicotine administration results in biphasic, brain-specific changes in kynurenate levels in the rat.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(4):697-704.
2005: Yasco Aracava; Edna F R Pereira; Alfred Maelicke; Edson X Albuquerque
Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-aspartate receptors in rat hippocampal neurons.
The Journal of pharmacology and experimental therapeutics 2005;312(3):1195-205.
2004: Maria F M Braga; Edna F R Pereira; Arpad Mike; Edson X Albuquerque
Pb2+ via protein kinase C inhibits nicotinic cholinergic modulation of synaptic transmission in the hippocampus.
The Journal of pharmacology and experimental therapeutics 2004;311(2):700-10.
2004: Manickavasagom Alkondon; Edna F R Pereira; Ping Yu; Emerson Z Arruda; Luis E F Almeida; Paolo Guidetti; William P Fawcett; Michael T Sapko; William R Randall; Robert Schwarcz; Danilo A Tagle; Edson X Albuquerque
Targeted deletion of the kynurenine aminotransferase ii gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via alpha7 nicotinic receptors in the hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(19):4635-48.
2004: Luis E F Almeida; Edna F R Pereira; Adriana L Camara; Alfred Maelicke; Edson X Albuquerque
Sensitivity of neuronal nicotinic acetylcholine receptors to the opiate antagonists naltrexone and naloxone: receptor blockade and up-regulation.
Bioorganic & medicinal chemistry letters 2004;14(8):1879-87.
2004: Hélio R Santos; Wagner M Cintra; Yasco Aracava; Carla Mendes Maciel; Newton G Castro; Edson X Albuquerque
Spine density and dendritic branching pattern of hippocampal CA1 pyramidal neurons in neonatal rats chronically exposed to the organophosphate paraoxon.
Neurotoxicology 2004;25(3):481-94.
2004: Manickavasagom Alkondon; Edson X Albuquerque
The nicotinic acetylcholine receptor subtypes and their function in the hippocampus and cerebral cortex.
Progress in brain research 2004;145():109-20.
2003: Ricardo Menegatti; Anna C Cunha; Vitor F Ferreira; Edna F R Perreira; Ahmed El-Nabawi; Amira T Eldefrawi; Edson X Albuquerque; Gilda Neves; S M K Rates; Carlos A M Fraga; Eliezer J Barreiro
Design, synthesis and pharmacological profile of novel dopamine D2 receptor ligands.
Bioorganic & medicinal chemistry 2003;11(22):4807-13.
2003: Manickavasagom Alkondon; Edna F R Pereira; Edson X Albuquerque
NMDA and AMPA receptors contribute to the nicotinic cholinergic excitation of CA1 interneurons in the rat hippocampus.
Journal of neurophysiology 2003;90(3):1613-25.
2003: Marek Samochocki; Anja Höffle; Andreas Fehrenbacher; Ruth Jostock; Jürgen Ludwig; Claudia Christner; Martin Radina; Marion Zerlin; Christoph Ullmer; Edna F R Pereira; Hermann Lübbert; Edson X Albuquerque; Alfred Maelicke
Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors.
The Journal of pharmacology and experimental therapeutics 2003;305(3):1024-36.
2003: Mariton D Santos; Edna F R Pereira; Yasco Aracava; Newton G Castro; William P Fawcett; William R Randall; Edson X Albuquerque
Low concentrations of pyridostigmine prevent soman-induced inhibition of GABAergic transmission in the central nervous system: involvement of muscarinic receptors.
The Journal of pharmacology and experimental therapeutics 2003;304(1):254-65.
2002: Edna F R Pereira; Corey Hilmas; Mariton D Santos; Manickavasagom Alkondon; Alfred Maelicke; Edson X Albuquerque
Unconventional ligands and modulators of nicotinic receptors.
Journal of neurobiology 2002;53(4):479-500.
2002: Mariton D Santos; Manickavasagom Alkondon; Edna F R Pereira; Yasco Aracava; Howard M Eisenberg; Alfred Maelicke; Edson X Albuquerque
The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system.
Molecular pharmacology 2002;61(5):1222-34.
2002: Manickavasagom Alkondon; Edson X Albuquerque
A non-alpha7 nicotinic acetylcholine receptor modulates excitatory input to hippocampal CA1 interneurons.
Journal of neurophysiology 2002;87(3):1651-4.
2002: M R Priel; Edson X Albuquerque
Short-term effects of pilocarpine on rat hippocampal neurons in culture.
Epilepsia 2002;43 Suppl 5():40-6.
2001: Manickavasagom Alkondon; Edson X Albuquerque
Nicotinic acetylcholine receptor alpha7 and alpha4beta2 subtypes differentially control GABAergic input to CA1 neurons in rat hippocampus.
Journal of neurophysiology 2001;86(6):3043-55.
2001: Y Wang; Edna F R Pereira; AD Maus; Norma Ostlie; D Navaneetham; S Lei; Edson X Albuquerque; Bianca M Conti-Fine
Human bronchial epithelial and endothelial cells express alpha7 nicotinic acetylcholine receptors.
Molecular pharmacology 2001;60(6):1201-9.
2001: Hugo Gonzalez-Serratos; Ruzhang Chang; Edna F R Pereira; Newton G Castro; Yasco Aracava; P A Melo; Patricia C Lima; Carlos A M Fraga; Eliezer J Barreiro; Edson X Albuquerque
A novel thienylhydrazone, (2-thienylidene)3,4-methylenedioxybenzoylhydrazine, increases inotropism and decreases fatigue of skeletal muscle.
The Journal of pharmacology and experimental therapeutics 2001;299(2):558-66.
2001: C Hilmas; Edna F R Pereira; Manickavasagom Alkondon; Arash Rassoulpour; Robert Schwarcz; Edson X Albuquerque
The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(19):7463-73.
2001: Edson X Albuquerque; Mariton D Santos; Manickavasagom Alkondon; Edna F R Pereira; Alfred Maelicke
Modulation of nicotinic receptor activity in the central nervous system: a novel approach to the treatment of Alzheimer disease.
Alzheimer disease and associated disorders 2001;15 Suppl 1():S19-25.
2001: Paulo A Melo; Noelson M V Silva; Flávia V Brito; Camilla D Buarque; D V de Souza; Verônica Pinto Rodrigues; E S Poças; François Noël; Edson X Albuquerque; Paulo R R Costa
Synthesis and preliminary pharmacological evaluation of coumestans with different patterns of oxygenation.
Bioorganic & medicinal chemistry letters 2001;11(3):283-6.
2001: Alfred Maelicke; Marek Samochocki; Ruth Jostock; A Fehrenbacher; Jürgen Ludwig; Edson X Albuquerque; Marion Zerlin
Allosteric sensitization of nicotinic receptors by galantamine, a new treatment strategy for Alzheimer's disease.
Biological psychiatry 2001;49(3):279-88.
2000: Arpad Mike; Newton G Castro; Edson X Albuquerque
Choline and acetylcholine have similar kinetic properties of activation and desensitization on the alpha7 nicotinic receptors in rat hippocampal neurons.
Brain research 2000;882(1-2):155-68.
2000: Luis E F Almeida; Edna F R Pereira; Manickavasagom Alkondon; William P Fawcett; William R Randall; Edson X Albuquerque
The opioid antagonist naltrexone inhibits activity and alters expression of alpha7 and alpha4beta2 nicotinic receptors in hippocampal neurons: implications for smoking cessation programs.
Neuropharmacology 2000;39(13):2740-55.
2000: Manickavasagom Alkondon; Edna F R Pereira; Luis E F Almeida; William R Randall; Edson X Albuquerque
Nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in CA1 interneurons of rat hippocampus.
Neuropharmacology 2000;39(13):2726-39.
2000: Arpad Mike; Edna F R Pereira; Edson X Albuquerque
Ca(2+)-sensitive inhibition by Pb(2+) of alpha7-containing nicotinic acetylcholine receptors in hippocampal neurons.
Brain research 2000;873(1):112-23.
2000: Alfred Maelicke; André Schrattenholz; Marek Samochocki; Martin Radina; Edson X Albuquerque
Allosterically potentiating ligands of nicotinic receptors as a treatment strategy for Alzheimer's disease.
Behavioural brain research 2000;113(1-2):199-206.
2000: Edson X Albuquerque; Edna F R Pereira; Arpad Mike; Howard M Eisenberg; Alfred Maelicke; Manickavasagom Alkondon
Neuronal nicotinic receptors in synaptic functions in humans and rats: physiological and clinical relevance.
Behavioural brain research 2000;113(1-2):131-41.
2000: Alfred Maelicke; Edson X Albuquerque
Allosteric modulation of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer's disease.
European journal of pharmacology 2000;393(1-3):165-70.
2000: Manickavasagom Alkondon; Maria F M Braga; Edna F R Pereira; Alfred Maelicke; Edson X Albuquerque
alpha7 nicotinic acetylcholine receptors and modulation of gabaergic synaptic transmission in the hippocampus.
European journal of pharmacology 2000;393(1-3):59-67.
2000: Marek Samochocki; Marion Zerlin; Ruth Jostock; Paul J Groot-Kormelink; Walter Luyten; Edson X Albuquerque; Alfred Maelicke
Galantamine is an allosterically potentiating ligand of the human alpha4/beta2 nAChR.
Acta neurologica Scandinavica. Supplementum 2000;176():68-73.
2000: Manickavasagom Alkondon; Edna F R Pereira; Howard M Eisenberg; Edson X Albuquerque
Nicotinic receptor activation in human cerebral cortical interneurons: a mechanism for inhibition and disinhibition of neuronal networks.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(1):66-75.
1999: SR Chebabo; Mariton D Santos; Edson X Albuquerque
The organophosphate sarin, at low concentrations, inhibits the evoked release of GABA in rat hippocampal slices.
Neurotoxicology 1999;20(6):871-82.
1999: ES Rocha; Mariton D Santos; SR Chebabo; Yasco Aracava; Edson X Albuquerque
Low concentrations of the organophosphate VX affect spontaneous and evoked transmitter release from hippocampal neurons: toxicological relevance of cholinesterase-independent actions.
Toxicology and applied pharmacology 1999;159(1):31-40.
1999: U Fischer; S Reinhardt; Edson X Albuquerque; Alfred Maelicke
Expression of functional alpha7 nicotinic acetylcholine receptor during mammalian muscle development and denervation.
The European journal of neuroscience 1999;11(8):2856-64.
1999: Andrea Wevers; LM Monteggia; S Nowacki; Wilhelm Bloch; Ulrich Schütz; Jon Lindstrom; Edna F R Pereira; Howard M Eisenberg; Ezio Giacobini; Rob A I de Vos; Ernst N H Jansen Steur; Alfred Maelicke; Edson X Albuquerque; Hannsjörg Schröder
Expression of nicotinic acetylcholine receptor subunits in the cerebral cortex in Alzheimer's disease: histotopographical correlation with amyloid plaques and hyperphosphorylated-tau protein.
The European journal of neuroscience 1999;11(7):2551-65.
1999: Ronald J. Lukas; Jean-Pierre Changeux; N Le Novère; Edson X Albuquerque; David J K Balfour; D K Berg; D Bertrand; V A Chiappinelli; P B Clarke; A C Collins; J A Dani; Sharon R Grady; K J Kellar; Jon M Lindstrom; M J Marks; Maryka Quik; P W Taylor; S Wonnacott
International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits.
Pharmacological reviews 1999;51(2):397-401.
1999: Maria F M Braga; Edna F R Pereira; Edson X Albuquerque
Nanomolar concentrations of lead inhibit glutamatergic and GABAergic transmission in hippocampal neurons.
Brain research 1999;826(1):22-34.
1999: Maria F M Braga; Edna F R Pereira; M Marchioro; Edson X Albuquerque
Lead increases tetrodotoxin-insensitive spontaneous release of glutamate and GABA from hippocampal neurons.
Brain research 1999;826(1):10-21.
1999: Manickavasagom Alkondon; Edna F R Pereira; Howard M Eisenberg; Edson X Albuquerque
Choline and selective antagonists identify two subtypes of nicotinic acetylcholine receptors that modulate GABA release from CA1 interneurons in rat hippocampal slices.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(7):2693-705.
1998: Edson X Albuquerque; Edna F R Pereira; Maria F M Braga; H Matsubayashi; Manickavasagom Alkondon
Neuronal nicotinic receptors modulate synaptic function in the hippocampus and are sensitive to blockade by the convulsant strychnine and by the anti-Parkinson drug amantadine.
Toxicology letters 1998;102-103():211-8.
1998: Manickavasagom Alkondon; Edna F R Pereira; Edson X Albuquerque
alpha-bungarotoxin- and methyllycaconitine-sensitive nicotinic receptors mediate fast synaptic transmission in interneurons of rat hippocampal slices.
Brain research 1998;810(1-2):257-63.
1998: AD Maus; Edna F R Pereira; Peter I Karachunski; RM Horton; D Navaneetham; KD Macklin; WS Cortes; Edson X Albuquerque; Bianca M Conti-Fine
Human and rodent bronchial epithelial cells express functional nicotinic acetylcholine receptors.
Molecular pharmacology 1998;54(5):779-88.
1998: KD Macklin; AD Maus; Edna F R Pereira; Edson X Albuquerque; Bianca M Conti-Fine
Human vascular endothelial cells express functional nicotinic acetylcholine receptors.
The Journal of pharmacology and experimental therapeutics 1998;287(1):435-9.
1998: Edson X Albuquerque; Edna F R Pereira; Maria F M Braga; Manickavasagom Alkondon
Contribution of nicotinic receptors to the function of synapses in the central nervous system: the action of choline as a selective agonist of alpha 7 receptors.
Journal of physiology, Paris 1998;92(3-4):309-16.
1998: H Matsubayashi; Manickavasagom Alkondon; Edna F R Pereira; K L Swanson; Edson X Albuquerque
Strychnine: a potent competitive antagonist of alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal neurons.
The Journal of pharmacology and experimental therapeutics 1998;284(3):904-13.
1998: ES Rocha; SR Chebabo; Mariton D Santos; Yasco Aracava; Edson X Albuquerque
An analysis of low level doses of cholinesterase inhibitors in cultured neurons and hippocampal slices of rats.
Drug and chemical toxicology 1998;21 Suppl 1():191-200.
1997: Manickavasagom Alkondon; Edna F R Pereira; WS Cortes; Alfred Maelicke; Edson X Albuquerque
Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons.
The European journal of neuroscience 1997;9(12):2734-42.
1997: Manickavasagom Alkondon; Edna F R Pereira; C T Barbosa; Edson X Albuquerque
Neuronal nicotinic acetylcholine receptor activation modulates gamma-aminobutyric acid release from CA1 neurons of rat hippocampal slices.
The Journal of pharmacology and experimental therapeutics 1997;283(3):1396-411.
1997: H Matsubayashi; K L Swanson; Edson X Albuquerque
Amantadine inhibits nicotinic acetylcholine receptor function in hippocampal neurons.
The Journal of pharmacology and experimental therapeutics 1997;281(2):834-44.
1997: Edson X Albuquerque; Manickavasagom Alkondon; Edna F R Pereira; Newton G Castro; André Schrattenholz; C T Barbosa; R Bonfante-Cabarcas; Yasco Aracava; Howard M Eisenberg; Alfred Maelicke
Properties of neuronal nicotinic acetylcholine receptors: pharmacological characterization and modulation of synaptic function.
The Journal of pharmacology and experimental therapeutics 1997;280(3):1117-36.
1997: Edson X Albuquerque; Edna F R Pereira; Manickavasagom Alkondon; André Schrattenholz; Alfred Maelicke
Nicotinic acetylcholine receptors on hippocampal neurons: distribution on the neuronal surface and modulation of receptor activity.
Journal of receptor and signal transduction research 1997;17(1-3):243-66.
1997: Alfred Maelicke; T Coban; A Storch; André Schrattenholz; Edna F R Pereira; Edson X Albuquerque
Allosteric modulation of Torpedo nicotinic acetylcholine receptor ion channel activity by noncompetitive agonists.
Journal of receptor and signal transduction research 1997;17(1-3):11-28.
1996: Manickavasagom Alkondon; Edna F R Pereira; Edson X Albuquerque
Mapping the location of functional nicotinic and gamma-aminobutyric acidA receptors on hippocampal neurons.
The Journal of pharmacology and experimental therapeutics 1996;279(3):1491-506.
1996: M Marchioro; K L Swanson; Yasco Aracava; Edson X Albuquerque
Glycine and calcium-dependent effects of lead on N-methyl-D-aspartate receptor function in rat hippocampal neurons.
The Journal of pharmacology and experimental therapeutics 1996;279(1):143-53.
1996: Edna F R Pereira; Manickavasagom Alkondon; J M McIntosh; Edson X Albuquerque
Alpha-conotoxin-ImI: a competitive antagonist at alpha-bungarotoxin-sensitive neuronal nicotinic receptors in hippocampal neurons.
The Journal of pharmacology and experimental therapeutics 1996;278(3):1472-83.
1996: Manickavasagom Alkondon; E S Rocha; Alfred Maelicke; Edson X Albuquerque
Diversity of nicotinic acetylcholine receptors in rat brain. V. alpha-Bungarotoxin-sensitive nicotinic receptors in olfactory bulb neurons and presynaptic modulation of glutamate release.
The Journal of pharmacology and experimental therapeutics 1996;278(3):1460-71.
1996: E S Rocha; K L Swanson; Yasco Aracava; J E Goolsby; Alfred Maelicke; Edson X Albuquerque
Paraoxon: cholinesterase-independent stimulation of transmitter release and selective block of ligand-gated ion channels in cultured hippocampal neurons.
The Journal of pharmacology and experimental therapeutics 1996;278(3):1175-87.
1996: C T Barbosa; Manickavasagom Alkondon; Yasco Aracava; Alfred Maelicke; Edson X Albuquerque
Ligand-gated ion channels in acutely dissociated rat hippocampal neurons with long dendrites.
Neuroscience letters 1996;210(3):177-80.
1996: R Bonfante-Cabarcas; K L Swanson; Manickavasagom Alkondon; Edson X Albuquerque
Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. IV. Regulation by external Ca++ of alpha-bungarotoxin-sensitive receptor function and of rectification induced by internal Mg++.
The Journal of pharmacology and experimental therapeutics 1996;277(1):432-44.
1996: Edson X Albuquerque; Edna F R Pereira; R Bonfante-Cabarcas; M Marchioro; H Matsubayashi; Manickavasagom Alkondon; Alfred Maelicke
Nicotinic acetylcholine receptors on hippocampal neurons: cell compartment-specific expression and modulatory control of channel activity.
Progress in brain research 1996;109():111-24.
1996: André Schrattenholz; Edna F R Pereira; U Roth; K H Weber; Edson X Albuquerque; Alfred Maelicke
Agonist responses of neuronal nicotinic acetylcholine receptors are potentiated by a novel class of allosterically acting ligands.
Molecular pharmacology 1996;49(1):1-6.
1995: Sergei A Grando; R M Horton; Edna F R Pereira; Brenda M Diethelm-Okita; P M George; Edson X Albuquerque; Bianca M Conti-Fine
A nicotinic acetylcholine receptor regulating cell adhesion and motility is expressed in human keratinocytes.
The Journal of investigative dermatology 1995;105(6):774-81.
1995: Manickavasagom Alkondon; Edson X Albuquerque
Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. III. Agonist actions of the novel alkaloid epibatidine and analysis of type II current.
The Journal of pharmacology and experimental therapeutics 1995;274(2):771-82.
1995: K Ishihara; Manickavasagom Alkondon; J G Montes; Edson X Albuquerque
Nicotinic responses in acutely dissociated rat hippocampal neurons and the selective blockade of fast-desensitizing nicotinic currents by lead.
The Journal of pharmacology and experimental therapeutics 1995;273(3):1471-82.
1995: K Ishihara; Manickavasagom Alkondon; J G Montes; Edson X Albuquerque
Ontogenically related properties of N-methyl-D-aspartate receptors in rat hippocampal neurons and the age-specific sensitivity of developing neurons to lead.
The Journal of pharmacology and experimental therapeutics 1995;273(3):1459-70.
1995: Edson X Albuquerque; Edna F R Pereira; Newton G Castro; Manickavasagom Alkondon; S Reinhardt; H Schröder; Alfred Maelicke
Nicotinic receptor function in the mammalian central nervous system.
Annals of the New York Academy of Sciences 1995;757():48-72.
1995: Newton G Castro; Edson X Albuquerque
alpha-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability.
Biophysical journal 1995;68(2):516-24.
1995: Alfred Maelicke; André Schrattenholz; A Storch; B Schroder; O Gutbrod; C Methfessel; K H Weber; Edna F R Pereira; Manickavasagom Alkondon; Edson X Albuquerque
Noncompetitive agonism at nicotinic acetylcholine receptors; functional significance for CNS signal transduction.
Journal of receptor and signal transduction research 1995;15(1-4):333-53.
1994: Manickavasagom Alkondon; S Reinhardt; C Lobron; B Hermsen; Alfred Maelicke; Edson X Albuquerque
Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. II. The rundown and inward rectification of agonist-elicited whole-cell currents and identification of receptor subunits by in situ hybridization.
The Journal of pharmacology and experimental therapeutics 1994;271(1):494-506.
1994: Edna F R Pereira; Manickavasagom Alkondon; S Reinhardt; Alfred Maelicke; X Peng; J Lindstrom; P Whiting; Edson X Albuquerque
Physostigmine and galanthamine: probes for a novel binding site on the alpha 4 beta 2 subtype of neuronal nicotinic acetylcholine receptors stably expressed in fibroblast cells.
The Journal of pharmacology and experimental therapeutics 1994;270(2):768-78.
1994: Manickavasagom Alkondon; Edson X Albuquerque
Presence of alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat olfactory bulb neurons.
Neuroscience letters 1994;176(2):152-6.
1994: M E Nelson; Edson X Albuquerque
9-Aminoacridines act at a site different from that for Mg2+ in blockade of the N-methyl-D-aspartate receptor channel.
Molecular pharmacology 1994;46(1):151-60.
1994: André Schrattenholz; U Roth; A Schuhen; H J Schäfer; Jasminka Godovac-Zimmermann; Edson X Albuquerque; Alfred Maelicke
Identification of purine binding sites on Torpedo acetylcholine receptor.
Journal of receptor research 1994;14(3-4):197-208.
1994: Alberto Costa; Edson X Albuquerque
Dynamics of the actions of tetrahydro-9-aminoacridine and 9-aminoacridine on glutamatergic currents: concentration-jump studies in cultured rat hippocampal neurons.
The Journal of pharmacology and experimental therapeutics 1994;268(1):503-14.
1993: Newton G Castro; Edson X Albuquerque
Brief-lifetime, fast-inactivating ion channels account for the alpha-bungarotoxin-sensitive nicotinic response in hippocampal neurons.
Neuroscience letters 1993;164(1-2):137-40.
1993: André Schrattenholz; Jasminka Godovac-Zimmermann; H J Schäfer; Edson X Albuquerque; Alfred Maelicke
Photoaffinity labeling of Torpedo acetylcholine receptor by physostigmine.
European journal of biochemistry / FEBS 1993;216(2):671-7.
1993: Alfred Maelicke; T Coban; André Schrattenholz; B Schröder; S Reinhardt-Maelicke; A Storch; Jasminka Godovac-Zimmermann; C Methfessel; Edna F R Pereira; Edson X Albuquerque
Physostigmine and neuromuscular transmission.
Annals of the New York Academy of Sciences 1993;681():140-54.
1993: Edna F R Pereira; S Reinhardt-Maelicke; André Schrattenholz; Alfred Maelicke; Edson X Albuquerque
Identification and functional characterization of a new agonist site on nicotinic acetylcholine receptors of cultured hippocampal neurons.
The Journal of pharmacology and experimental therapeutics 1993;265(3):1474-91.
1993: Manickavasagom Alkondon; Edson X Albuquerque
Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes.
The Journal of pharmacology and experimental therapeutics 1993;265(3):1455-73.
1993: P Thomas; M Stephens; G Wilkie; M Amar; George Lunt; P Whiting; T Gallagher; Edna F R Pereira; Manickavasagom Alkondon; Edson X Albuquerque
(+)-Anatoxin-a is a potent agonist at neuronal nicotinic acetylcholine receptors.
Journal of neurochemistry 1993;60(6):2308-11.
1993: Janine L Good; R K Khurana; RF Mayer; Wagner M Cintra; Edson X Albuquerque
Pathophysiological studies of neuromuscular function in subacute organophosphate poisoning induced by phosmet.
Journal of neurology, neurosurgery, and psychiatry 1993;56(3):290-4.
1993: I N Cestari; Edson X Albuquerque; David R Burt
A PCR shortcut to oocyte expression.
BioTechniques 1993;14(3):404-7.
1993: Edna F R Pereira; Manickavasagom Alkondon; T Tano; Newton G Castro; M M Fróes-Ferrão; R Rozental; R S Aronstam; André Schrattenholz; Alfred Maelicke; Edson X Albuquerque
A novel agonist binding site on nicotinic acetylcholine receptors.
Journal of receptor research 1993;13(1-4):413-36.
1993: André Schrattenholz; T Coban; B Schröder; K O Okonjo; J Kuhlmann; Edna F R Pereira; Edson X Albuquerque; Alfred Maelicke
Biochemical characterization of a novel channel-activating site on nicotinic acetylcholine receptors.
Journal of receptor research 1993;13(1-4):393-412.
1992: H Ujihara; Edson X Albuquerque
Developmental change of the inhibition by lead of NMDA-activated currents in cultured hippocampal neurons.
The Journal of pharmacology and experimental therapeutics 1992;263(2):868-75.
1992: H Ujihara; Edson X Albuquerque
Ontogeny of N-methyl-D-aspartate-induced current in cultured hippocampal neurons.
The Journal of pharmacology and experimental therapeutics 1992;263(2):859-67.
1992: K L Swanson; Edson X Albuquerque
Progress in understanding the nicotinic acetylcholine receptor function at central and peripheral nervous system synapses through toxin interactions.
Maryland medical journal (Baltimore, Md. : 1985) 1992;41(7):623-31.
1992: Manickavasagom Alkondon; Edna F R Pereira; Susan Wonnacott; Edson X Albuquerque
Blockade of nicotinic currents in hippocampal neurons defines methyllycaconitine as a potent and specific receptor antagonist.
Molecular pharmacology 1992;41(4):802-8.
1992: Edna F R Pereira; Yasco Aracava; R S Aronstam; Eliezer J Barreiro; Edson X Albuquerque
Pyrazole, an alcohol dehydrogenase inhibitor, has dual effects on N-methyl-D-aspartate receptors of hippocampal pyramidal cells: agonist and noncompetitive antagonist.
The Journal of pharmacology and experimental therapeutics 1992;261(1):331-40.
1992: Ian P Stolerman; Edson X Albuquerque; H S Garcha
Behavioural effects of anatoxin, a potent nicotinic agonist, in rats.
Neuropharmacology 1992;31(3):311-4.
1992: Susan Wonnacott; K L Swanson; Edson X Albuquerque; N J Huby; P Thompson; T Gallagher
Homoanatoxin: a potent analogue of anatoxin-A.
Biochemical pharmacology 1992;43(3):419-23.
1992: Michael Adler; Sharad S Deshpande; R E Foster; D M Maxwell; Edson X Albuquerque
Effects of subacute pyridostigmine administration on mammalian skeletal muscle function.
Journal of applied toxicology : JAT 1992;12(1):25-33.
1991: V K Reddy; S S Deshpande; Wagner M Cintra; G T Scoble; Edson X Albuquerque
Effectiveness of oximes 2-PAM and HI-6 in recovery of muscle function depressed by organophosphate agents in the rat hemidiaphragm: an in vitro study.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1991;17(4):746-60.
1991: Susan Wonnacott; S Jackman; K L Swanson; H Rapoport; Edson X Albuquerque
Nicotinic pharmacology of anatoxin analogs. II. Side chain structure-activity relationships at neuronal nicotinic ligand binding sites.
The Journal of pharmacology and experimental therapeutics 1991;259(1):387-91.
1991: K L Swanson; R S Aronstam; Susan Wonnacott; H Rapoport; Edson X Albuquerque
Nicotinic pharmacology of anatoxin analogs. I. Side chain structure-activity relationships at peripheral agonist and noncompetitive antagonist sites.
The Journal of pharmacology and experimental therapeutics 1991;259(1):377-86.
1991: M Kawabuchi; Wagner M Cintra; S S Deshpande; Edson X Albuquerque
Morphological and electrophysiological study of distal motor nerve fiber degeneration and sprouting after irreversible cholinesterase inhibition.
Synapse (New York, N.Y.) 1991;8(3):218-28.
1991: Manickavasagom Alkondon; Edson X Albuquerque
Initial characterization of the nicotinic acetylcholine receptors in rat hippocampal neurons.
Journal of receptor research 1991;11(6):1001-21.
1991: Edson X Albuquerque; Alberto Costa; Manickavasagom Alkondon; K P Shaw; A S Ramoa; Yasco Aracava
Functional properties of the nicotinic and glutamatergic receptors.
Journal of receptor research 1991;11(1-4):603-25.
1991: Yasco Aracava; M M Fróes-Ferrão; Edna F R Pereira; Edson X Albuquerque
Sensitivity of N-methyl-D-aspartate (NMDA) and nicotinic acetylcholine receptors to ethanol and pyrazole.
Annals of the New York Academy of Sciences 1991;625():451-72.
1990: Manickavasagom Alkondon; Edson X Albuquerque
alpha-Cobratoxin blocks the nicotinic acetylcholine receptor in rat hippocampal neurons.
European journal of pharmacology 1990;191(3):505-6.
1990: A S Ramoa; Manickavasagom Alkondon; Yasco Aracava; J Irons; George Lunt; S S Deshpande; Susan Wonnacott; R S Aronstam; Edson X Albuquerque
The anticonvulsant MK-801 interacts with peripheral and central nicotinic acetylcholine receptor ion channels.
The Journal of pharmacology and experimental therapeutics 1990;254(1):71-82.
1990: Manickavasagom Alkondon; Alberto Costa; V Radhakrishnan; R S Aronstam; Edson X Albuquerque
Selective blockade of NMDA-activated channel currents may be implicated in learning deficits caused by lead.
FEBS letters 1990;261(1):124-30.
1990: P Kofuji; Yasco Aracava; K L Swanson; R S Aronstam; H Rapoport; Edson X Albuquerque
Activation and blockade of the acetylcholine receptor-ion channel by the agonists (+)-anatoxin-a, the N-methyl derivative and the enantiomer.
The Journal of pharmacology and experimental therapeutics 1990;252(2):517-25.
1990: Alberto Costa; K L Swanson; Yasco Aracava; R S Aronstam; Edson X Albuquerque
Molecular effects of dimethylanatoxin on the peripheral nicotinic acetylcholine receptor.
The Journal of pharmacology and experimental therapeutics 1990;252(2):507-16.
1989: R Rozental; Yasco Aracava; G T Scoble; K L Swanson; Susan Wonnacott; Edson X Albuquerque
Agonist recognition site of the peripheral acetylcholine receptor ion channel complex differentiates the enantiomers of nicotine.
The Journal of pharmacology and experimental therapeutics 1989;251(2):395-404.
1989: Manickavasagom Alkondon; Edson X Albuquerque
The nonoxime bispyridinium compound SAD-128 alters the kinetic properties of the nicotinic acetylcholine receptor ion channel: a possible mechanism for antidotal effects.
The Journal of pharmacology and experimental therapeutics 1989;250(3):842-52.
1989: M T Lima-Landman; Edson X Albuquerque
Ethanol potentiates and blocks NMDA-activated single-channel currents in rat hippocampal pyramidal cells.
FEBS letters 1989;247(1):61-7.
1989: R Rozental; G T Scoble; Edson X Albuquerque; M Idriss; S Sherby; David B Sattelle; K Nakanishi; K Konno; Amira T Eldefrawi; ME Eldefrawi
Allosteric inhibition of nicotinic acetylcholine receptors of vertebrates and insects by philanthotoxin.
The Journal of pharmacology and experimental therapeutics 1989;249(1):123-30.
1989: K L Swanson; Yasco Aracava; F J Sardina; H Rapoport; R S Aronstam; Edson X Albuquerque
N-methylanatoxinol isomers: derivatives of the agonist (+)-anatoxin-a block the nicotinic acetylcholine receptor ion channel.
Molecular pharmacology 1989;35(2):223-31.
1989: M Kawabuchi; A F Boyne; S S Deshpande; Edson X Albuquerque
The reversible carbamate, (-)physostigmine, reduces the size of synaptic end plate lesions induced by sarin, an irreversible organophosphate.
Toxicology and applied pharmacology 1989;97(1):98-106.
1988: A S Ramoa; Edson X Albuquerque
Phencyclidine and some of its analogues have distinct effects on NMDA receptors of rat hippocampal neurons.
FEBS letters 1988;235(1-2):156-62.
1988: Manickavasagom Alkondon; K S Rao; Edson X Albuquerque
Acetylcholinesterase reactivators modify the functional properties of the nicotinic acetylcholine receptor ion channel.
The Journal of pharmacology and experimental therapeutics 1988;245(2):543-56.
1988: R S Aronstam; M W Edwards; J W Daly; Edson X Albuquerque
Interactions of piperidine derivatives with the nicotinic cholinergic receptor complex from Torpedo electric organ.
Neurochemical research 1988;13(2):171-6.
1988: D R Macallan; George Lunt; Susan Wonnacott; K L Swanson; H Rapoport; Edson X Albuquerque
Methyllycaconitine and (+)-anatoxin-a differentiate between nicotinic receptors in vertebrate and invertebrate nervous systems.
FEBS letters 1988;226(2):357-63.
1988: M Kawabuchi; A F Boyne; S S Deshpande; Wagner M Cintra; Arnold Brossi; Edson X Albuquerque
Enantiomer (+)physostigmine prevents organophosphate-induced subjunctional damage at the neuromuscular synapse by a mechanism not related to cholinesterase carbamylation.
Synapse (New York, N.Y.) 1988;2(2):139-47.
1988: Edson X Albuquerque; Yasco Aracava; Wagner M Cintra; Arnold Brossi; B Schönenberger; S S Deshpande
Structure-activity relationship of reversible cholinesterase inhibitors: activation, channel blockade and stereospecificity of the nicotinic acetylcholine receptor-ion channel complex.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1988;21(6):1173-96.
1988: Edson X Albuquerque; J W Daly; Jordan E Warnick
Macromolecular sites for specific neurotoxins and drugs on chemosensitive synapses and electrical excitation in biological membranes.
Ion channels 1988;1():95-162.
1987: L G Aguayo; Edson X Albuquerque
Phencyclidine blocks two potassium currents in spinal neurons in cell culture.
Brain research 1987;436(1):9-17.
1987: K L Swanson; Edson X Albuquerque
Nicotinic acetylcholine receptor ion channel blockade by cocaine: the mechanism of synaptic action.
The Journal of pharmacology and experimental therapeutics 1987;243(3):1202-10.
1987: K S Rao; Jordan E Warnick; J W Daly; Edson X Albuquerque
Pharmacology of the alkaloid pumiliotoxin-B. II. Possible involvement of calcium and sodium-dependent processes in nerve and skeletal muscle.
The Journal of pharmacology and experimental therapeutics 1987;243(2):775-83.
1987: Yasco Aracava; S S Deshpande; K L Swanson; H Rapoport; Susan Wonnacott; George Lunt; Edson X Albuquerque
Nicotinic acetylcholine receptors in cultured neurons from the hippocampus and brain stem of the rat characterized by single channel recording.
FEBS letters 1987;222(1):63-70.
1987: L Oliveira; B W Madsen; N Kapai; S M Sherby; K L Swanson; ME Eldefrawi; Edson X Albuquerque
Interaction of narcotic antagonist naltrexone with nicotinic acetylcholine receptor.
European journal of pharmacology 1987;140(3):331-42.
1987: Charles N Allen; Edson X Albuquerque
Conductance properties of GABA-activated chloride currents recorded from cultured hippocampal neurons.
Brain research 1987;410(1):159-63.
1987: C Rapier; Susan Wonnacott; George Lunt; Edson X Albuquerque
The neurotoxin histrionicotoxin interacts with the putative ion channel of the nicotinic acetylcholine receptors in the central nervous system.
FEBS letters 1987;212(2):292-6.
1987: Yasco Aracava; S S Deshpande; D L Rickett; Arnold Brossi; B Schönenberger; Edson X Albuquerque
The molecular basis of anticholinesterase actions on nicotinic and glutamatergic synapses.
Annals of the New York Academy of Sciences 1987;505():226-55.
1987: K S Rao; Yasco Aracava; D L Rickett; Edson X Albuquerque
Noncompetitive blockade of the nicotinic acetylcholine receptor-ion channel complex by an irreversible cholinesterase inhibitor.
The Journal of pharmacology and experimental therapeutics 1987;240(1):337-44.
1986: L G Aguayo; Edson X Albuquerque
Blockade and recovery of the acetylcholine receptor produced by a thienyl analog of phencyclidine: influence of voltage, temperature, frequency of stimulation and conditioning pulse duration.
The Journal of pharmacology and experimental therapeutics 1986;239(1):25-31.
1986: L G Aguayo; Edson X Albuquerque
Effects of phencyclidine and its analogs on the end-plate current of the neuromuscular junction.
The Journal of pharmacology and experimental therapeutics 1986;239(1):15-24.
1986: M K Idriss; L G Aguayo; D L Rickett; Edson X Albuquerque
Organophosphate and carbamate compounds have pre- and postjunctional effects at the insect glutamatergic synapse.
The Journal of pharmacology and experimental therapeutics 1986;239(1):279-85.
1986: R S Aronstam; J W Daly; T F Spande; T K Narayanan; Edson X Albuquerque
Interaction of gephyrotoxin and indolizidine alkaloids with the nicotinic acetylcholine receptor-ion channel complex of Torpedo electroplax.
Neurochemical research 1986;11(8):1227-40.
1986: PM Sokolove; Edson X Albuquerque; F C Kauffman; T F Spande; J W Daly
Phenolic antioxidants: potent inhibitors of the (Ca2+ + Mg2+)-ATPase of sarcoplasmic reticulum.
FEBS letters 1986;203(2):121-6.
1986: L G Aguayo; B Witkop; Edson X Albuquerque
Voltage- and time-dependent effects of phencyclidines on the endplate current arise from open and closed channel blockade.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(10):3523-7.
1986: Edson X Albuquerque; S S Deshpande; Yasco Aracava; Manickavasagom Alkondon; J W Daly
A possible involvement of cyclic AMP in the expression of desensitization of the nicotinic acetylcholine receptor. A study with forskolin and its analogs.
FEBS letters 1986;199(1):113-20.
1986: S S Deshpande; G B Viana; F C Kauffman; D L Rickett; Edson X Albuquerque
Effectiveness of physostigmine as a pretreatment drug for protection of rats from organophosphate poisoning.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1986;6(3):566-77.
1986: K L Swanson; Charles N Allen; R S Aronstam; H Rapoport; Edson X Albuquerque
Molecular mechanisms of the potent and stereospecific nicotinic receptor agonist (+)-anatoxin-a.
Molecular pharmacology 1986;29(3):250-7.
1986: Charles N Allen; Edson X Albuquerque
Characteristics of acetylcholine-activated channels of innervated and chronically denervated skeletal muscles.
Experimental neurology 1986;91(3):532-45.
1985: Edson X Albuquerque; S S Deshpande; M Kawabuchi; Yasco Aracava; M Idriss; D L Rickett; A F Boyne
Multiple actions of anticholinesterase agents on chemosensitive synapses: molecular basis for prophylaxis and treatment of organophosphate poisoning.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1985;5(6 Pt 2):S182-203.
1985: K P Shaw; Yasco Aracava; A Akaike; J W Daly; D L Rickett; Edson X Albuquerque
The reversible cholinesterase inhibitor physostigmine has channel-blocking and agonist effects on the acetylcholine receptor-ion channel complex.
Molecular pharmacology 1985;28(6):527-38.
1985: M Idriss; Edson X Albuquerque
Phencyclidine (PCP) blocks glutamate-activated postsynaptic currents.
FEBS letters 1985;189(1):150-6.
1985: R S Aronstam; C T King; Edson X Albuquerque; J W Daly; D M Feigl
Binding of [3H]perhydrohistrionicotoxin and [3H]phencyclidine to the nicotinic receptor-ion channel complex of Torpedo electroplax. Inhibition by histrionicotoxins and derivatives.
Biochemical pharmacology 1985;34(17):3037-47.
1985: W A Varanda; Yasco Aracava; S M Sherby; W G VanMeter; ME Eldefrawi; Edson X Albuquerque
The acetylcholine receptor of the neuromuscular junction recognizes mecamylamine as a noncompetitive antagonist.
Molecular pharmacology 1985;28(2):128-37.
1985: C K Meshul; A F Boyne; S S Deshpande; Edson X Albuquerque
Comparison of the ultrastructural myopathy induced by anticholinesterase agents at the end plates of rat soleus and extensor muscles.
Experimental neurology 1985;89(1):96-114.
1985: B W Madsen; Edson X Albuquerque
The narcotic antagonist naltrexone has a biphasic effect on the nicotinic acetylcholine receptor.
FEBS letters 1985;182(1):20-4.
1985: S M Sherby; Amira T Eldefrawi; Edson X Albuquerque; ME Eldefrawi
Comparison of the actions of carbamate anticholinesterases on the nicotinic acetylcholine receptor.
Molecular pharmacology 1985;27(3):343-8.
1985: C E Spivak; Edson X Albuquerque
Triphenylmethylphosphonium blocks the nicotinic acetylcholine receptor noncompetitively.
Molecular pharmacology 1985;27(2):246-55.
1984: S P Yeagle; Edson X Albuquerque
Reinnervation of normal and dystrophic skeletal muscle.
Experimental neurology 1984;86(1):1-17.
1984: Yasco Aracava; Edson X Albuquerque
Meproadifen enhances activation and desensitization of the acetylcholine receptor-ionic channel complex (AChR): single channel studies.
FEBS letters 1984;174(2):267-74.
1984: Yasco Aracava; S R Ikeda; J W Daly; Neville Brookes; Edson X Albuquerque
Interactions of bupivacaine with ionic channels of the nicotinic receptor. Analysis of single-channel currents.
Molecular pharmacology 1984;26(2):304-13.
1984: S R Ikeda; R S Aronstam; J W Daly; Yasco Aracava; Edson X Albuquerque
Interactions of bupivacaine with ionic channels of the nicotinic receptor. Electrophysiological and biochemical studies.
Molecular pharmacology 1984;26(2):293-303.
1984: MA Maleque; K Takahashi; B Witkop; Arnold Brossi; Edson X Albuquerque
A study of the novel synthetic analog (+/-)-depentylperhydrohistrionicotoxin on the nicotinic receptor-ion channel complex.
The Journal of pharmacology and experimental therapeutics 1984;230(3):619-26.
1984: C Souccar; W A Varanda; R S Aronstam; J W Daly; Edson X Albuquerque
Interactions of gephyrotoxin with the acetylcholine receptor-ionic channel complex. II. Enhancement of desensitization.
Molecular pharmacology 1984;25(3):395-400.
1984: C Souccar; W A Varanda; J W Daly; Edson X Albuquerque
Interactions of gephyrotoxin with the acetylcholine receptor-ionic channel complex. I. Blockade of the ionic channel.
Molecular pharmacology 1984;25(3):384-94.
1984: Esam E El-Fakahany; Amira T Eldefrawi; D L Murphy; L G Aguayo; D J Triggle; Edson X Albuquerque; ME Eldefrawi
Interactions of phencyclidine with crayfish muscle membranes. Sensitivity to calcium channel antagonists and other drugs.
Molecular pharmacology 1984;25(3):369-78.
1984: C S Hudson; S S Deshpande; Edson X Albuquerque
Consequences of axonal transport blockade by batrachotoxin on mammalian neuromuscular junction. III. An ultrastructural study.
Brain research 1984;296(2):319-32.
1984: Edson X Albuquerque; A Akaike; K P Shaw; D L Rickett
The interaction of anticholinesterase agents with the acetylcholine receptor-ionic channel complex.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1984;4(2 Pt 2):S27-33.
1984: MA Maleque; Arnold Brossi; B Witkop; S A Godleski; Edson X Albuquerque
Interaction of analogs of histrionicotoxin with the acetylcholine receptor ionic channel complex and membrane excitability.
The Journal of pharmacology and experimental therapeutics 1984;229(1):72-9.
1984: G J Pascuzzo; A Akaike; MA Maleque; K P Shaw; R S Aronstam; D L Rickett; Edson X Albuquerque
The nature of the interactions of pyridostigmine with the nicotinic acetylcholine receptor-ionic channel complex. I. Agonist, desensitizing, and binding properties.
Molecular pharmacology 1984;25(1):92-101.
1984: A Akaike; S R Ikeda; Neville Brookes; G J Pascuzzo; D L Rickett; Edson X Albuquerque
The nature of the interactions of pyridostigmine with the nicotinic acetylcholine receptor-ionic channel complex. II. Patch clamp studies.
Molecular pharmacology 1984;25(1):102-12.
1984: L G Aguayo; HAREL WEINSTEIN; S Maayani; S D Glick; Jordan E Warnick; Edson X Albuquerque
Discriminant effects of behaviorally active and inactive analogs of phencyclidine on membrane electrical excitability.
The Journal of pharmacology and experimental therapeutics 1984;228(1):80-7.
1984: Jordan E Warnick; MA Maleque; Edson X Albuquerque
Interaction of bicyclo-octane analogs of amantadine with ionic channels of the nicotinic acetylcholine receptor and electrically excitable membrane.
The Journal of pharmacology and experimental therapeutics 1984;228(1):73-9.
1984: Charles N Allen; A Akaike; Edson X Albuquerque
The frog interosseal muscle fiber as a new model for patch clamp studies of chemosensitive- and voltage-sensitive ion channels: actions of acetylcholine and batrachotoxin.
Journal de physiologie 1984;79(4):338-43.
1983: C E Spivak; MA Maleque; K Takahashi; Arnold Brossi; Edson X Albuquerque
The ionic channel of the nicotinic acetylcholine receptor is unable to differentiate between the optical antipodes of perhydrohistrionicotoxin.
FEBS letters 1983;163(2):189-93.
1983: M Kalia; S S Deshpande; Thomas B Ducker; Edson X Albuquerque
Evaluation of regeneration of nerve and reinnervation of skeletal muscle in the hibernating ground squirrel.
Experimental neurology 1983;81(2):407-25.
1983: Edson X Albuquerque; L G Aguayo; Jordan E Warnick; R K Ickowicz; Mordecai P Blaustein
Interactions of phencyclidine with ion channels of nerve and muscle: behavioral implications.
Federation proceedings 1983;42(9):2584-9.
1983: C E Spivak; J Waters; B Witkop; Edson X Albuquerque
Potencies and channel properties induced by semirigid agonists at frog nicotinic acetylcholine receptors.
Molecular pharmacology 1983;23(2):337-43.
1983: Jonathan Carp; R S Aronstam; B Witkop; Edson X Albuquerque
Electrophysiological and biochemical studies on enhancement of desensitization by phenothiazine neuroleptics.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(1):310-4.
1982: S S Deshpande; E C Hall-Craggs; Edson X Albuquerque
Electrophysiological and morphological investigation of bupivacaine-induced myopathy and terminal sprouting in the rat.
Experimental neurology 1982;78(3):740-64.
1982: MA Maleque; C Souccar; jonathan cohen; Edson X Albuquerque
Meproadifen reaction with the ionic channel of the acetylcholine receptor: potentiation of agonist-induced desensitization at the frog neuromuscular junction.
Molecular pharmacology 1982;22(3):636-47.
1982: Jordan E Warnick; P J Jessup; L E Overman; ME Eldefrawi; Y Nimit; J W Daly; Edson X Albuquerque
Pumiliotoxin-C and synthetic analogues. A new class of nicotinic antagonists.
Molecular pharmacology 1982;22(3):565-73.
1982: K Takahashi; Arthur E Jacobson; C P Mak; B Witkop; Arnold Brossi; Edson X Albuquerque; Jordan E Warnick; MA Maleque; A Bavoso; J V Silverton
(+/-)-2-Depentylperhydrohistrionicotoxin: a new probe for a regulatory site on the nicotinic acetylcholine receptor-channel.
Journal of medicinal chemistry 1982;25(8):919-25.
1982: Jordan E Warnick; MA Maleque; N Bakry; Amira T Eldefrawi; Edson X Albuquerque
Structure-activity relationships of amantadine. I. Interaction of the N-alkyl analogues with the ionic channels of the nicotinic acetylcholine receptor and electrically excitable membrane.
Molecular pharmacology 1982;22(1):82-93.
1982: L G Aguayo; Jordan E Warnick; S Maayani; S D Glick; HAREL WEINSTEIN; Edson X Albuquerque
Site of action of phencyclidine. IV. Interaction of phencyclidine and its analogues on ionic channels of the electrically excitable membrane and nicotinic receptor: implications for behavioral effects.
Molecular pharmacology 1982;21(3):637-47.
1982: C E Spivak; MA Maleque; A C Oliveira; L M Masukawa; T Tokuyama; J W Daly; Edson X Albuquerque
Actions of the histrionicotoxins at the ion channel of the nicotinic acetylcholine receptor and at the voltage-sensitive ion channels of muscle membranes.
Molecular pharmacology 1982;21(2):351-61.
1982: S R Max; S S Deshpande; Edson X Albuquerque
Neural regulation of muscle glucose 6-phosphate dehydrogenase: effect of batrachotoxin and tetrodotoxin.
Journal of neurochemistry 1982;38(2):386-91.
1982: N Shaker; Amira T Eldefrawi; L G Aguayo; Jordan E Warnick; Edson X Albuquerque; ME Eldefrawi
Interactions of d-tubocurarine with the nicotinic acetylcholine receptor/channel molecule.
The Journal of pharmacology and experimental therapeutics 1982;220(1):172-7.
1981: L Guth; Charles P Barrett; E J Donati; S S Deshpande; Edson X Albuquerque
Histopathological reactions an axonal regeneration in the transected spinal cord of Hibernating squirrels.
The Journal of comparative neurology 1981;203(2):297-308.
1981: MA Maleque; Jordan E Warnick; Edson X Albuquerque
The mechanism and site of action of ketamine on skeletal muscle.
The Journal of pharmacology and experimental therapeutics 1981;219(3):638-45.
1981: Edson X Albuquerque; L G Aguayo; Jordan E Warnick; HAREL WEINSTEIN; S D Glick; S Maayani; R K Ickowicz; Mordecai P Blaustein
The behavioral effects of phencyclidines may be due to their blockade of potassium channels.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(12):7792-6.
1981: S S Deshpande; R J Boegman; Edson X Albuquerque
Consequences of axonal transport blockade by batrachotoxin on mammalian neuromuscular junction. II. Late pre- and postsynaptic changes.
Brain research 1981;225(1):115-29.
1981: ME Eldefrawi; N Shaker; N A Mansour; Jordan E Warnick; Edson X Albuquerque
Detection of nicotinic cholinergic transmission in Malapterurus electricus electroplax.
Life sciences 1981;29(10):1033-7.
1981: R Tamburini; Edson X Albuquerque; J W Daly; F C Kauffman
Inhibition of calcium-dependent ATPase from sarcoplasmic reticulum by a new class of indolizidine alkaloids, pumiliotoxins A, B, and 251D.
Journal of neurochemistry 1981;37(3):775-80.
1981: L G Aguayo; B Pazhenchevsky; J W Daly; Edson X Albuquerque
The ionic channel of the acetylcholine receptor. Regulation by sites outside and inside the cell membrane which are sensitive to quaternary ligands.
Molecular pharmacology 1981;20(2):345-55.
1981: G G Schofield; B Witkop; Jordan E Warnick; Edson X Albuquerque
Differentiation of the open and closed states of the ionic channels of nicotinic acetylcholine receptors by tricyclic antidepressants.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(8):5240-4.
1981: L Guth; V F Kemerer; T A Samaras; Jordan E Warnick; Edson X Albuquerque
The roles of disuse and loss of neurotrophic function in denervation atrophy of skeletal muscle.
Experimental neurology 1981;73(1):20-36.
1981: John E Rash; C S Hudson; W F Graham; RF Mayer; Jordan E Warnick; Edson X Albuquerque
Freeze fracture studies of human neuromuscular junctions. Membrane alterations observed in myasthenia gravis.
Laboratory investigation; a journal of technical methods and pathology 1981;44(6):519-30.
1981: G G Schofield; Jordan E Warnick; Edson X Albuquerque
Elucidation of the mechanism and site of action of quinuclidinyl benzilate (QNB) on the electrical excitability and chemosensitivity of the frog sartorius muscle.
Cellular and molecular neurobiology 1981;1(2):209-30.
1981: ME Eldefrawi; Jordan E Warnick; G G Schofield; Edson X Albuquerque; Amira T Eldefrawi
Interaction of imipramine with the ionic channel of the acetylcholine receptor of motor endplate and electric organ.
Biochemical pharmacology 1981;30(11):1391-4.
1981: Edson X Albuquerque; Jordan E Warnick; MA Maleque; F C Kauffman; R Tamburini; Y Nimit; J W Daly
The pharmacology of pumiliotoxin-B. I. Interaction with calcium sites in the sarcoplasmic reticulum of skeletal muscle.
Molecular pharmacology 1981;19(3):411-24.
1981: R S Aronstam; Amira T Eldefrawi; I N Pessah; J W Daly; Edson X Albuquerque; ME Eldefrawi
Regulation of [3H]perhydrohistrionicotoxin binding to Torpedo ocellata electroplax by effectors of the acetylcholine receptor.
The Journal of biological chemistry 1981;256(6):2843-50.
1981: G B Brown; S C Tieszen; J W Daly; Jordan E Warnick; Edson X Albuquerque
Batrachotoxinin-A 20-alpha-benzoate: a new radioactive ligand for voltage sensitive sodium channels.
Cellular and molecular neurobiology 1981;1(1):19-40.
1981: John E Rash; C S Hudson; Edson X Albuquerque; ME Eldefrawi; RF Mayer; W F Graham; T J Johnson; F D Giddings
Freeze-fracture, labelled-replica, and electrophysiological studies of junctional fold destruction in myasthenia gravis and experimental autoimmune myasthenia gravis.
Annals of the New York Academy of Sciences 1981;377():38-60.
1981: Edson X Albuquerque; Jordan E Warnick; RF Mayer; Amira T Eldefrawi; ME Eldefrawi
Recent advances in the molecular mechanisms of human and animal models of myasthenia gravis.
Annals of the New York Academy of Sciences 1981;377():496-518.
1981: J C Matthews; Jordan E Warnick; Edson X Albuquerque; ME Eldefrawi
Characterization of the electrogenic sodium channel from rat brain membranes using neurotoxin-dependent 22Na uptake.
Membrane biochemistry 1981;4(2):71-104.
1980: ME Eldefrawi; Amira T Eldefrawi; R S Aronstam; MA Maleque; Jordan E Warnick; Edson X Albuquerque
[3H]Phencyclidine: a probe for the ionic channel of the nicotinic receptor.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(12):7458-62.
1980: C E Spivak; B Witkop; Edson X Albuquerque
Anatoxin-a: a novel, potent agonist at the nicotinic receptor.
Molecular pharmacology 1980;18(3):384-94.
1980: S S Deshpande; Jordan E Warnick; L Guth; Edson X Albuquerque
Quantal release of acetylcholine does not regulate the resting membrane potential of mammalian skeletal muscle: evidence from in vivo experiments.
Experimental neurology 1980;70(1):122-37.
1980: R S Aronstam; ME Eldefrawi; Amira T Eldefrawi; Edson X Albuquerque; K F Jim; D J Triggle
Sites of action of phencyclidine. III. Interactions with muscarinic receptors.
Molecular pharmacology 1980;18(2):179-84.
1980: M C Tsai; Edson X Albuquerque; R S Aronstam; Amira T Eldefrawi; ME Eldefrawi; D J Triggle
Sites of action of phencyclidine. I. Effects on the electrical excitability and chemosensitive properties of the neuromuscular junction of skeletal muscle.
Molecular pharmacology 1980;18(2):159-66.
1980: Edson X Albuquerque; M C Tsai; R S Aronstam; Amira T Eldefrawi; ME Eldefrawi
Sites of action of phencyclidine. II. Interaction with the ionic channel of the nicotinic receptor.
Molecular pharmacology 1980;18(2):167-78.
1980: J W Daly; C W Myers; Jordan E Warnick; Edson X Albuquerque
Levels of batrachotoxin and lack of sensitivity to its action in poison-dart frogs (Phyllobates).
Science (New York, N.Y.) 1980;208(4450):1383-5.
1980: L Guth; E Richman; Charles P Barrett; Jordan E Warnick; Edson X Albuquerque
The mechanism by which degenerating peripheral nerve produces extrajunctional acetylcholine sensitivity in mammalian skeletal muscle.
Experimental neurology 1980;68(3):465-76.
1980: R J Boegman; Edson X Albuquerque
Axonal transport of cholinergic enzymes in the sciatic nerve of the hibernating and nonhibernating ground squirrel.
Experimental neurology 1980;68(3):521-30.
1980: R J Boegman; Edson X Albuquerque
Axonal transport in rats rendered paraplegic following a single subarachnoid injection of either batrachotoxin or 6-aminonicotinamide into the spinal cord.
Journal of neurobiology 1980;11(3):283-90.
1980: R J Boegman; S S Deshpande; Edson X Albuquerque
Consequences of axonal transport blockade induced by batrachotoxin on mammalian neuromuscular junction I. Early pre- and postsynaptic changes.
Brain research 1980;187(1):183-96.
1980: ME Eldefrawi; R S Aronstam; N M Bakry; Amira T Eldefrawi; Edson X Albuquerque
Activation, inactivation, and desensitization of acetylcholine receptor channel complex detected by binding of perhydrohistrionicotoxin.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(4):2309-13.
1980: Amira T Eldefrawi; N M Bakry; ME Eldefrawi; M C Tsai; Edson X Albuquerque
Nereistoxin interaction with the acetylcholine receptor-ionic channel complex.
Molecular pharmacology 1980;17(2):172-9.
1980: L Guth; S Smith; E J Donati; Edson X Albuquerque
Induction of intramuscular collateral nerve sprouting by neurally applied colchicine.
Experimental neurology 1980;67(3):513-23.
1980: Edson X Albuquerque; M C Tsai; R S Aronstam; B Witkop; Amira T Eldefrawi; ME Eldefrawi
Phencyclidine interactions with the ionic channel of the acetylcholine receptor and electrogenic membrane.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(2):1224-8.
1980: L Guth; Edson X Albuquerque; S S Deshpande; Charles P Barrett; E J Donati; Jordan E Warnick
Ineffectiveness of enzyme therapy on regeneration in the transected spinal cord of the rat.
Journal of neurosurgery 1980;52(1):73-86.
1980: Edson X Albuquerque; M Adler; C E Spivak; L Aguayo
Mechanism of nicotinic channel activation and blockade.
Annals of the New York Academy of Sciences 1980;358():204-38.
1980: Edson X Albuquerque; Jordan E Warnick; L Guth
Spinal cord regeneration and paraplegia.
Progress in clinical and biological research 1980;39():41-62.
1979: Edson X Albuquerque; P W Gage; A C Oliveira
Differential effect of perhydrohistrionicotoxin on 'intrinsic' and 'extrinsic' end-plate responses.
The Journal of physiology 1979;297(0):423-42.
1979: J C Matthews; Edson X Albuquerque; ME Eldefrawi
Influence of batrachotoxin, veratridine, grayanotoxin 1 and tetrodotoxin on uptake of Na-22 by rat brain membrane preparations.
Life sciences 1979;25(19):1651-8.
1979: T N Tiedt; Edson X Albuquerque; N M Bakry; ME Eldefrawi; Amira T Eldefrawi
Voltage- and time-dependent actions of piperocaine on the ion channel of the acetylcholine receptor.
Molecular pharmacology 1979;16(3):909-21.
1979: Edson X Albuquerque; Amira T Eldefrawi; A C Oliveira; D S Copio; ME Eldefrawi
Myasthenia gravis animal model: quantitative analysis of the efficiency of pre- and postjunctional regions of intercostal muscles in rabbits immunized with Torpedo acetylcholine receptor.
Experimental neurology 1979;66(1):109-22.
1979: M C Tsai; A C Oliveira; Edson X Albuquerque; ME Eldefrawi; Amira T Eldefrawi
Mode of action of quinacrine on the acetylcholine receptor ionic channel complex.
Molecular pharmacology 1979;16(2):382-92.
1979: Y Mano; K Mano; RF Mayer; S S Deshpande; Edson X Albuquerque
Effects of paraplegia produced by intrathecal 6-aminonicotinamide on motor units in the rat.
Experimental neurology 1979;65(2):435-56.
1979: M Adler; A C Oliveira; Edson X Albuquerque; N A Mansour; Amira T Eldefrawi
Reaction of tetraethylammonium with the open and closed conformations of the acetylcholine receptor ionic channel complex.
The Journal of general physiology 1979;74(1):129-52.
1979: Jordan E Warnick; Edson X Albuquerque
Changes in genotypic expression, development, and the effects of chronic penicillamine treatment on the electrical properties of the posterior latissimus dorsi muscle in two lines of normal and dystrophic chickens.
Experimental neurology 1979;63(1):135-62.
1979: Edson X Albuquerque; A C Oliveira
Physiological studies on the ionic channel of nicotinic neuromuscular synapses.
Advances in cytopharmacology 1979;3():197-211.
1979: M Adler; A C Oliveira; ME Eldefrawi; Amira T Eldefrawi; Edson X Albuquerque
Tetraethylammonium: voltage-dependent action on endplate conductance and inhibition of ligand binding to postsynaptic proteins.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(1):531-5.
1979: Jordan E Warnick; F J Lebeda; Edson X Albuquerque
Junctional and extrajunctional aspects of inherited muscular dystrophy in chickens: development and pharmacology.
Annals of the New York Academy of Sciences 1979;317():263-84.
1978: ME Eldefrawi; Amira T Eldefrawi; N A Mansour; J W Daly; B Witkop; Edson X Albuquerque
Acetylcholine receptor and ionic channel of Torpedo electroplax: binding of perhydrohistrionicotoxin to membrane and solubilized preparations.
Biochemistry 1978;17(25):5474-84.
1978: Jordan E Warnick; Edson X Albuquerque
Models of paraplegia in animals: trophic relationships.
Federation proceedings 1978;37(14):2811-7.
1978: F C Kauffman; S S Deshpande; Edson X Albuquerque
Biochemical alterations in denervated skeletal muscle and transected sciatic nerve in the hibernating ground squirrel.
Experimental neurology 1978;62(2):335-46.
1978: Edson X Albuquerque; S S Deshpande; L Guth
Physiological properties of the innervated and denervated neuromuscular junction of hibernating and nonhibernating ground squirrels.
Experimental neurology 1978;62(2):347-73.
1978: L M Masukawa; Edson X Albuquerque
Voltage- and time-dependent action of histrionicotoxin on the endplate current of the frog muscle.
The Journal of general physiology 1978;72(3):351-67.
1978: M C Tsai; N A Mansour; Amira T Eldefrawi; ME Eldefrawi; Edson X Albuquerque
Mechanism of action of amantadine on neuromuscular transmission.
Molecular pharmacology 1978;14(5):787-803.
1978: C S Hudson; J E Rash; T N Tiedt; Edson X Albuquerque
Neostigmine-induced alterations at the mammalian neuromuscular junction. II. Ultrastructure.
The Journal of pharmacology and experimental therapeutics 1978;205(2):340-56.
1978: M Adler; Edson X Albuquerque; F J Lebeda
Kinetic analysis of end plate currents altered by atropine and scopolamine.
Molecular pharmacology 1978;14(3):514-29.
1978: T N Tiedt; Edson X Albuquerque; C S Hudson; J E Rash
Neostigmine-induced alterations at the mammalian neuromuscular junction. I. Muscle contraction and electrophysiology.
The Journal of pharmacology and experimental therapeutics 1978;205(2):326-39.
1978: Edson X Albuquerque; P W Gage
Differential effects of perhydrohistrionicotoxin on neurally and iontophoretically evoked endplate currents.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(3):1596-9.
1978: Edson X Albuquerque; Amira T Eldefrawi; ME Eldefrawi; N A Mansour; M C Tsai
Amantadine: neuromuscular blockade by suppression of ionic conductance of the acetylcholine receptor.
Science (New York, N.Y.) 1978;199(4330):788-90.
1978: J Grossie; Edson X Albuquerque
Extensor muscle responses to triamcinolone.
Experimental neurology 1978;58(3):435-45.
1978: JH Garcia; S S Deshpande; R S Pence; Edson X Albuquerque
Spinal myelopathy induced by subarachnoid batrachotoxin: ultrastructure and electrophysiology.
Brain research 1978;140(1):75-87.
1978: S S Deshpande; Edson X Albuquerque; F C Kauffman; L Guth
Physiological, biochemical and histological changes in skeletal muscle, neuromuscular junction and spinal cord of rats rendered paraplegic by subarachnoidal administration of 6-aminonicotinamide.
Brain research 1978;140(1):89-109.
1978: J M Sarvey; Edson X Albuquerque; Amira T Eldefrawi; ME Eldefrawi
Effects of alpha-bungarotoxin and reversible cholinergic ligands on normal and denervated mammalian skeletal muscle.
Membrane biochemistry 1978;1(1-2):131-57.
1978: D L Garrison; Edson X Albuquerque; Jordan E Warnick; J W Daly; B Witkop
Antagonism of carbamylcholine-induced depolarization by batrachotoxin and veratridine.
Molecular pharmacology 1978;14(1):111-21.
1978: L Guth; Edson X Albuquerque
The neurotrophic regulation of resting membrane potential and extrajunctional acetylcholine sensitivity in mammalian skeletal muscle.
Physiologia Bohemoslovaca 1978;27(5):401-14.
1977: T N Tiedt; Edson X Albuquerque; L Guth
Degenerating nerve fiber products do not alter physiological properties of adjacent innervated skeletal muscle fibers.
Science (New York, N.Y.) 1977;198(4319):839-41.
1977: RF Mayer; Edson X Albuquerque
Neuromuscular transmission in myasthenia.
Lancet 1977;2(8045):976-7.
1977: Jordan E Warnick; Edson X Albuquerque; L Guth
The demonstration of neurotrophic function by application of colchicine or vinblastine to the peripheral nerve.
Experimental neurology 1977;57(2):622-36.
1977: S R Max; S S Deshpande; Edson X Albuquerque
Neural regulation of muscle acetylcholinsterase: effects of batrachotoxin and 6-aminonicotinamide.
Brain research 1977;130(1):101-7.
1977: Amira T Eldefrawi; ME Eldefrawi; Edson X Albuquerque; A C Oliveira; N Mansour; M Adler; J W Daly; G B Brown; W Burgermeister; B Witkop
Perhydrohistrionicotoxin: a potential ligand for the ion conductance modulator of the acetylcholine receptor.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(5):2172-6.
1977: J O Dolly; Edson X Albuquerque; J Sarvey; B Mallick; E A Barnard
Binding of perhydro-histrionicotoxin to the postsynaptic membrane of skeletal muscle in relation to its blockage of acetylcholine-induced depolarization.
Molecular pharmacology 1977;13(1):1-14.
1977: RF Mayer; Edson X Albuquerque; J E Rash; C S Hudson
Neuromusclar junction and myasthenic crisis.
Transactions of the American Neurological Association 1977;102():100-4.
1976: J E Rash; Edson X Albuquerque; C S Hudson; RF Mayer; J R Satterfield
Studies of human myasthenia gravis: electrophysiological and ultrastructural evidence compatible with antibody attachment to acetylcholine receptor complex.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(12):4584-8.
1976: S S Deshpande; Edson X Albuquerque; L Guth
Neurotrophic regulation of prejunctional and postjunctional membrane at the mammalian motor endplate.
Experimental neurology 1976;53(1):151-65.
1976: Jordan E Warnick; Edson X Albuquerque; C R Diniz
Electrophysiological observations on the action of the purified scorpion venom, tityustoxin, on nerve and skeletal muscle of the rat.
The Journal of pharmacology and experimental therapeutics 1976;198(1):155-67.
1976: Edson X Albuquerque; J E Rash; RF Mayer; J R Satterfield
An electrophysiological and morphological study of the neuromuscular junction in patients with myasthenia gravis.
Experimental neurology 1976;51(3):536-63.
1976: G S Shotzberger; Edson X Albuquerque; J W Daly
The effects of batrachotoxin on cat papillary muscle.
The Journal of pharmacology and experimental therapeutics 1976;196(2):433-44.
1976: M Adler; Edson X Albuquerque
An analysis of the action of atropine and scopolamine on the end-plate current of frog sartorius muscle.
The Journal of pharmacology and experimental therapeutics 1976;196(2):360-72.
1976: Edson X Albuquerque; Neville Brookes; R Onur; Jordan E Warnick
Kinetics of interaction of batrachotoxin and tetrodotoxin on rat diaphragm muscle.
Molecular pharmacology 1976;12(1):82-91.
1976: F C Kauffman; Edson X Albuquerque; Jordan E Warnick; S R Max
Effect of vinblastine on neural regulation of metabolism in rat skeletal muscle.
Experimental neurology 1976;50(1):60-6.
1976: Edson X Albuquerque; F J Lebeda; S H Appel; R Almon; F C Kauffman; RF Mayer; T Narahashi; J Z Yeh
Effects of normal and myasthenic serum factors on innervated and chronically denervated mammalian muscles.
Annals of the New York Academy of Sciences 1976;274():475-92.
1975: S R Max; Edson X Albuquerque
Neurotrophic regulation of acetylcholinesterase in regenerating skeletal muscle.
Experimental neurology 1975;49(3):852-7.
1975: E A Barnard; J O Dolly; C W Porter; Edson X Albuquerque
The acetylcholine receptor and the ionic conductance modulation system of skeletal muscle.
Experimental neurology 1975;48(1):1-28.
1975: A J Lapa; Edson X Albuquerque; J M Sarvey; J Daly; B Witkop
Effects of histrionicotoxin on the chemosensitive and electrical properties of skeletal muscle.
Experimental neurology 1975;47(3):558-80.
1975: F J Lebeda; Edson X Albuquerque
Membrane cable properties of normal and dystrophic chicken muscle fibers.
Experimental neurology 1975;47(3):544-57.
1975: J J McArdle; Edson X Albuquerque
Effects of ouabain on denervated and dystrophic muscles of the mouse.
Experimental neurology 1975;47(2):353-6.
1975: Jordan E Warnick; Edson X Albuquerque; R Onur; S E Jansson; J Daly; T Tokuyama; B Witkop
The pharmacology of batrachotoxin. VII. Structure-activity relationships and the effects of pH.
The Journal of pharmacology and experimental therapeutics 1975;193(1):232-45.
1974: F C Kauffman; Jordan E Warnick; Edson X Albuquerque
Uptake of [3H]colchicine from silastic implants by mammalian nerves and muscles.
Experimental neurology 1974;44(3):404-16.
1974: Edson X Albuquerque; E A Barnard; C W Porter; Jordan E Warnick
The density of acetylcholine receptors and their sensitivity in the postsynaptic membrane of muscle endplates.
Proceedings of the National Academy of Sciences of the United States of America 1974;71(7):2818-22.
1974: S E Jansson; Edson X Albuquerque; J Daly
The pharmacology of batrachotoxin. VI. Effects on the mammalian motor nerve terminal.
The Journal of pharmacology and experimental therapeutics 1974;189(2):525-37.
1974: A J Lapa; Edson X Albuquerque; J Daly
An electrophysiological study of the effects of D-tubocurarine, atropine, and alpha-bungarotoxin on the cholinergic receptor in innervated and chronically denervated mammalian skeletal muscles.
Experimental neurology 1974;43(2):375-98.
1974: Edson X Albuquerque; K Kuba; J Daly
Effect of histrionicotoxin on the ionic conductance modulator of the cholinergic receptor: a quantitative analysis of the end-plate current.
The Journal of pharmacology and experimental therapeutics 1974;189(2):513-24.
1974: K Kuba; Edson X Albuquerque; J Daly; E A Barnard
A study of the irreversible cholinesterase inhibitor, diisopropylfluorophosphate, on time course of end-plate currents in frog sartorius muscle.
The Journal of pharmacology and experimental therapeutics 1974;189(2):499-512.
1974: T H Chiu; A J Lapa; E A Barnard; Edson X Albuquerque
Binding of D-tubocurarine and alpha-bungarotoxin in normal and denervated mouse muscles.
Experimental neurology 1974;43(2):399-413.
1974: F J Lebeda; Jordan E Warnick; Edson X Albuquerque
Electrical and chemosensitive properties of normal and dystrophic chicken muscles.
Experimental neurology 1974;43(1):21-37.
1974: Edson X Albuquerque; Jordan E Warnick; F M Sansone; R Onur
Trophic functions of the neuron. 3. Mechanisms of neurotrophic interactions. The effects of vinblastine and colchicine on neural regulation of muscle.
Annals of the New York Academy of Sciences 1974;228(0):224-43.
1973: K Kuba; Edson X Albuquerque; E A Barnard
Diisopropylfluorophosphate: suppression of ionic conductance of the cholinergic receptor.
Science (New York, N.Y.) 1973;181(4102):853-6.
1973: M Sasa; B P Avner; Edson X Albuquerque
Actions of beta-blocking agents on membrane excitability of the lobster giant axon.
European journal of pharmacology 1973;23(1):97-103.
1973: Edson X Albuquerque; E A Barnard; S E Jansson; J Wieckowski
Occupancy of the cholinergic receptors in relation to changes in the endplate potential.
Life sciences 1973;12(12):545-52.
1973: Edson X Albuquerque; E A Barnard; T H Chiu; A J Lapa; J O Dolly; S E Jansson; J Daly; B Witkop
Acetylcholine receptor and ion conductance modulator sites at the murine neuromuscular junction: evidence from specific toxin reactions.
Proceedings of the National Academy of Sciences of the United States of America 1973;70(3):949-53.
1973: Edson X Albuquerque; I Seyama; T Narahashi
Characterization of batrachotoxin-induced depolarization of the squid giant axons.
The Journal of pharmacology and experimental therapeutics 1973;184(2):308-14.
1973: Edson X Albuquerque; Jordan E Warnick; F M Sansone; J Daly
The pharmacology of batrachotoxin. V. A comparative study of membrane properties and the effect of batrachotoxin on sartorius muscles of the frogs Phyllobates aurotaenia and Rana pipiens.
The Journal of pharmacology and experimental therapeutics 1973;184(2):315-29.
1973: J J McArdle; Edson X Albuquerque
A study of the reinnervation of fast and slow mammalian muscles.
The Journal of general physiology 1973;61(1):1-23.
1972: Edson X Albuquerque; Jordan E Warnick; J R Tasse; F M Sansone
Effects of vinblastine and colchicine on neural regulation of the fast and slow skeletal muscles of the rat.
Experimental neurology 1972;37(3):607-34.
1972: J Daly; Edson X Albuquerque; F C Kauffman; F Oesch
Effects of batrachotoxin on electroplax Na + -K + -ATPase and levels of ATP in rat muscle.
Journal of neurochemistry 1972;19(12):2829-33.
1972: Edson X Albuquerque
The mode of action of batrachotoxin.
Federation proceedings 1972;31(3):1133-8.
1972: Edson X Albuquerque; M Sasa; J M Sarvey
Batrachotoxin has no effect on the electrogenic membranes of lobster and crayfish muscles.
Life sciences. Pt. 1: Physiology and pharmacology 1972;11(7):357-63.
1972: Edson X Albuquerque; Jordan E Warnick
The pharmacology of batrachotoxin. IV. Interaction with tetrodotoxin on innervated and chronically denervated rat skeletal muscle.
The Journal of pharmacology and experimental therapeutics 1972;180(3):683-97.
1971: Edson X Albuquerque; M Sasa; B P Avner
Possible site of action of batrachotoxin.
Nature: New biology 1971;234(46):93-5.
1971: T Narahashi; Edson X Albuquerque; T Deguchi
Effects of batrachotoxin on membrane potential and conductance of squid giant axons.
The Journal of general physiology 1971;58(1):54-70.
1971: Edson X Albuquerque; Jordan E Warnick
Electrophysiological observations in normal and dystrophic chicken muscles.
Science (New York, N.Y.) 1971;172(3989):1260-3.
1971: Edson X Albuquerque; J W Daly; B Witkop
Batrachotoxin: chemistry and pharmacology.
Science (New York, N.Y.) 1971;172(3987):995-1002.
1971: P M Hogan; Edson X Albuquerque
The pharmacology of batrachotoxin. 3. Effect on the heart Purkinje fibers.
The Journal of pharmacology and experimental therapeutics 1971;176(3):529-37.
1971: Edson X Albuquerque; Jordan E Warnick; F M Sansone
The pharmacology of batrachotoxin. II. Effect on electrical properties of the mammalian nerve and skeletal muscle membranes.
The Journal of pharmacology and experimental therapeutics 1971;176(3):511-28.
1971: Jordan E Warnick; Edson X Albuquerque; F M Sansone
The pharmacology of batrachotoxin. I. Effects on the contractile mechanism and on neuromuscular transmission of mammalian skeletal muscle.
The Journal of pharmacology and experimental therapeutics 1971;176(3):497-510.
1971: T Narahashi; T Deguchi; Edson X Albuquerque
Effects of batrachotoxin on nerve membrane potential and conductances.
Nature: New biology 1971;229(7):221-2.
1971: Edson X Albuquerque; F T Schuh; F C Kauffman
Early membrane depolarization of the fast mammalian muscle after denervation.
Pflügers Archiv : European journal of physiology 1971;328(1):36-50.
1970: S O Kayaalp; Edson X Albuquerque; Jordan E Warnick
Ganglionic and cardiac actions of batrachotoxin.
European journal of pharmacology 1970;12(1):10-8.
1970: F C Kauffman; Edson X Albuquerque
Effect of ischemia and denervation on metabolism of fast and slow mammalian skeletal muscle.
Experimental neurology 1970;28(1):46-63.
1970: Edson X Albuquerque; R J McIsaac
Fast and slow mammalian muscles after denervation.
Experimental neurology 1970;26(1):183-202.
1969: Edson X Albuquerque; R J McIsaac
Early development of acetylcholine receptors on fast and slow mammalian skeletal muscle.
Life sciences 1969;8(7):409-16.
1969: Edson X Albuquerque; S H Chung; D Ottoson
The action of tetrodotoxin on the frog's isolated muscle spindle.
Acta physiologica Scandinavica 1969;75(3):301-12.
1968: Edson X Albuquerque; Barry L Whitsel; C M Smith
Patterns of muscle spindle afferent stimulation by alkylammonium compounds.
The Journal of pharmacology and experimental therapeutics 1968;164(1):191-201.
1968: Edson X Albuquerque; S Thesleff
A comparative study of membrane properties of innervated and chronically denervated fast and slow skeletal muscles of the rat.
Acta physiologica Scandinavica 1968;73(4):471-80.
1968: Edson X Albuquerque; M D Sokoll; B Sonesson; S Thesleff
Studies on the nature of the cholinergic receptor.
European journal of pharmacology 1968;4(1):40-6.
1968: Edson X Albuquerque; S Thesleff
The effect of calcium on the skeletal muscle membrane after treatment with phospholipase C.
Acta physiologica Scandinavica 1968;72(3):310-21.
1968: Edson X Albuquerque; W Grampp
Effects of tetrodotoxin on the slowly adapting stretch receptor neurone of lobster.
The Journal of physiology 1968;195(1):141-56.
1968: Edson X Albuquerque; S Thesleff
Effects of phospholipase A and lysolecithin on some electrical properties of the muscle membrane.
Acta physiologica Scandinavica 1968;72(1):248-52.
1967: C M Smith; Edson X Albuquerque
Differences in the tubocurarine antagonism of the activation of muscle spindle afferents by siccinylcholine, acetylcholine and nicotine.
The Journal of pharmacology and experimental therapeutics 1967;156(3):573-84.
1967: Edson X Albuquerque; S Thesleff
Influence of phospholipase C on some electrical properties of the skeletal muscle membrane.
The Journal of physiology 1967;190(1):123-37.
1965: Edson X Albuquerque; C M Smith
Stimulation of muscle spindle afferents by DMPP.
The Journal of pharmacology and experimental therapeutics 1965;149(3):320-8.
1964: Edson X Albuquerque; C M SMITH
SPECIFICITY OF EXCITATION OF MUSCLE SPINDLE AFFERENTS BY CHOLINERGIC SUBSTANCES.
The Journal of pharmacology and experimental therapeutics 1964;146():344-53.