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Lili Chen

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Yu Zhang; Mingyue Zheng; Jing Chen; Lili Chen; Lihong Hu; Chenjing Li; Hong Shen; Xu Shen; Xin-Gang Yao; Jiming Ye; Haitao Zhang; Hualiang Jiang
(+)-Rutamarin as a dual inducer of both GLUT4 translocation and expression efficiently ameliorates glucose homeostasis in insulin-resistant mice.
Kuifeng Wang; Qi Wang; Jing Chen; Lili Chen; Hualiang Jiang; Xu Shen
Crystal structure and enzymatic characterization of thymidylate synthase X from Helicobacter pylori strain SS1.
Haitao Zhang; Jing Chen; Lili Chen; Hualiang Jiang; Xu Shen
Structural basis for retinoic X receptor repression on the tetramer.

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2012: Yu Zhang; Mingyue Zheng; Jing Chen; Lili Chen; Lihong Hu; Chenjing Li; Hong Shen; Xu Shen; Xin-Gang Yao; Jiming Ye; Haitao Zhang; Hualiang Jiang
(+)-Rutamarin as a dual inducer of both GLUT4 translocation and expression efficiently ameliorates glucose homeostasis in insulin-resistant mice.
PloS one 2012;7(2):e31811.
2011: Kuifeng Wang; Qi Wang; Jing Chen; Lili Chen; Hualiang Jiang; Xu Shen
Crystal structure and enzymatic characterization of thymidylate synthase X from Helicobacter pylori strain SS1.
Protein science : a publication of the Protein Society 2011;20(8):1398-410.
2011: Haitao Zhang; Jing Chen; Lili Chen; Hualiang Jiang; Xu Shen
Structural basis for retinoic X receptor repression on the tetramer.
The Journal of biological chemistry 2011;286(28):24593-8.
2011: Haitao Zhang; Li Li; Lili Chen; Lihong Hu; Hualiang Jiang; Xu Shen
Structure basis of bigelovin as a selective RXR agonist with a distinct binding mode.
Journal of molecular biology 2011;407(1):13-20.
2011: Haitao Zhang; Rong Zhou; Li Li; Jing Chen; Lili Chen; Chenjing Li; Hong Ding; Liang Yu; Lihong Hu; Hualiang Jiang; Xu Shen
Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor.
The Journal of biological chemistry 2011;286(3):1868-75.
2011: Haitao Zhang; Xing Xu; Jing Chen; Lili Chen; Lihong Hu; Hualiang Jiang; Xu Shen
Molecular determinants of magnolol targeting both RXRα and PPARγ.
PloS one 2011;6(11):e28253.
2010: Qiong Liu; Lili Chen; Lihong Hu; Yuewei Guo; Xu Shen
Small molecules from natural sources, targeting signaling pathways in diabetes.
Biochimica et biophysica acta 2010;1799(10-12):854-65.
2010: Qiong Liu; Yu Zhang; Zhonghui Lin; Hong Shen; Lili Chen; Lihong Hu; Hualiang Jiang; Xu Shen
Danshen extract 15,16-dihydrotanshinone I functions as a potential modulator against metabolic syndrome through multi-target pathways.
The Journal of steroid biochemistry and molecular biology 2010;120(4-5):155-63.
2010: Yu Feng; Xiao Ding; Tao Chen; Lili Chen; Fang Liu; Xu Jia; Xiaomin Luo; Xu Shen; Kaixian Chen; Hualiang Jiang; Hui Wang; Hong Liu; Dongxiang Liu
Design, synthesis, and interaction study of quinazoline-2(1H)-thione derivatives as novel potential Bcl-xL inhibitors.
Journal of medicinal chemistry 2010;53(9):3465-79.
2008: Hong Shen; Yu Zhang; Hong Ding; Xu Wang; Lili Chen; Hualiang Jiang; Xu Shen
Farnesoid X receptor induces GLUT4 expression through FXR response element in the GLUT4 promoter.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2008;22(1-4):1-14.
2008: Yunhua Kong; Dalei Wu; Haiyun Bai; Cong Han; Jing Chen; Lili Chen; Lihong Hu; Hualiang Jiang; Xu Shen
Enzymatic characterization and inhibitor discovery of a new cystathionine {gamma}-synthase from Helicobacter pylori.
Journal of biochemistry 2008;143(1):59-68.
2007: Cong Han; Zhang Jian; Lili Chen; Kaixian Chen; Xu Shen; Hualiang Jiang
Discovery of Helicobacter pylori shikimate kinase inhibitors: bioassay and molecular modeling.
Bioorganic & medicinal chemistry 2007;15(2):656-62.
2006: Lili Chen; Shuai Chen; Chunshan Gui; Jianhua Shen; Xu Shen; Hualiang Jiang
Discovering severe acute respiratory syndrome coronavirus 3CL protease inhibitors: virtual screening, surface plasmon resonance, and fluorescence resonance energy transfer assays.
Journal of biomolecular screening 2006;11(8):915-21.
2006: Cong Han; Lirui Wang; Kunqian Yu; Lili Chen; Lihong Hu; Kaixian Chen; Hualiang Jiang; Xu Shen
Biochemical characterization and inhibitor discovery of shikimate dehydrogenase from Helicobacter pylori.
The FEBS journal 2006;273(20):4682-92.
2006: Shuai Chen; Haibin Luo; Lili Chen; Jing Chen; Jianhua Shen; Weiliang Zhu; Kaixian Chen; Xu Shen; Hualiang Jiang
An overall picture of SARS coronavirus (SARS-CoV) genome-encoded major proteins: structures, functions and drug development.
Current pharmaceutical design 2006;12(35):4539-53.
2005: Lili Chen; Chunshan Gui; Xiaomin Luo; Qingang Yang; Stephan Günther; Elke Scandella; Christian Drosten; Donglu Bai; Xichang He; Burkhard Ludewig; Jing Chen; Haibin Luo; Yiming Yang; Yifu Yang; Jianping Zou; Volker Thiel; Kaixian Chen; Jianhua Shen; Xu Shen; Hualiang Jiang
Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro.
Journal of virology 2005;79(11):7095-103.
2005: Changying Yu; Chunshan Gui; Haibin Luo; Lili Chen; Liang Zhang; Hao Yu; Sheng Yang; Weihong Jiang; Jianhua Shen; Xu Shen; Hualiang Jiang
Folding of the SARS coronavirus spike glycoprotein immunological fragment (SARS_S1b): thermodynamic and kinetic investigation correlating with three-dimensional structural modeling.
Biochemistry 2005;44(5):1453-63.
2005: Shuai Chen; Lili Chen; Jinzhi Tan; Jing Chen; Li Du; Tao Sun; Jianhua Shen; Kaixian Chen; Hualiang Jiang; Xu Shen
Severe acute respiratory syndrome coronavirus 3C-like proteinase N terminus is indispensable for proteolytic activity but not for enzyme dimerization. Biochemical and thermodynamic investigation in conjunction with molecular dynamics simulations.
The Journal of biological chemistry 2005;280(1):164-73.