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Manyin Chen

Research Profile

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Mei Sun; George J Wells; Ran Yan; Youan Liu; Mark Moon; Maral Ouzounian; Manyin Chen; Geoffrey de Couto; Masahiro Fukuoka; Anthony Gramolini; Guohua Li; Peter P Liu
Cathepsin-L ameliorates cardiac hypertrophy through activation of the autophagy-lysosomal dependent protein processing pathways.
Jing Lu; Ai-Bing Wang; Xiang Wei; Ling Yan; Qinglin Yang; Ran Zhang; Shu-Min Zhang; Yan Zhang; Xue Hai Zhu; Zhou-Yan Bian; Manyin Chen; Yingjie Chen; Ding-Sheng Jiang; Chen Liu; Peter P Liu; Hongliang Li
Interferon regulatory factor 3 is a negative regulator of pathological cardiac hypertrophy.
Marcelo Cypel; Marc De Perrot; Manyin Chen; Tiago Machuca; Andrew Pierre; Lianne G Singer; Thomas K Waddell; Kazuhiro Yasufuku; Jonathan C Yeung; Shaf Keshavjee
Experience with the first 50 ex vivo lung perfusions in clinical transplantation.

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All Publications

2013: Mei Sun; George J Wells; Ran Yan; Youan Liu; Mark Moon; Maral Ouzounian; Manyin Chen; Geoffrey de Couto; Masahiro Fukuoka; Anthony Gramolini; Guohua Li; Peter P Liu
Cathepsin-L ameliorates cardiac hypertrophy through activation of the autophagy-lysosomal dependent protein processing pathways.
Journal of the American Heart Association 2013;2(2):e000191.
2013: Jing Lu; Ai-Bing Wang; Xiang Wei; Ling Yan; Qinglin Yang; Ran Zhang; Shu-Min Zhang; Yan Zhang; Xue Hai Zhu; Zhou-Yan Bian; Manyin Chen; Yingjie Chen; Ding-Sheng Jiang; Chen Liu; Peter P Liu; Hongliang Li
Interferon regulatory factor 3 is a negative regulator of pathological cardiac hypertrophy.
Basic research in cardiology 2013;108(2):326.
2012: Marcelo Cypel; Marc De Perrot; Manyin Chen; Tiago Machuca; Andrew Pierre; Lianne G Singer; Thomas K Waddell; Kazuhiro Yasufuku; Jonathan C Yeung; Shaf Keshavjee
Experience with the first 50 ex vivo lung perfusions in clinical transplantation.
The Journal of thoracic and cardiovascular surgery 2012;144(5):1200-6.
2012: Jonathan C Yeung; Riccardo Bonato; Manyin Chen; Douglas J Cook; Marcelo Cypel; Terumoto Koike; Mingyao Liu; Tiago N Machuca; Masaaki Sato; Arthur S Slutsky; Thomas K Waddell; Shaf Keshavjee
Physiologic assessment of the ex vivo donor lung for transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2012;31(10):1120-6.
2012: Zhou-Yan Bian; Manyin Chen; Yingjie Chen; Shan Deng; John Fassett; Jinghua Feng; You-Wen He; Ding-Sheng Jiang; Chen Liu; Peter P Liu; Qi-Zhu Tang; Xiang Wei; Ling Yan; Qinglin Yang; Lian-Feng Zhang; Yan Zhang; Hongliang Li
Disruption of mindin exacerbates cardiac hypertrophy and fibrosis.
Journal of molecular medicine (Berlin, Germany) 2012;90(8):895-910.
2011: Ling Yan; Qinglin Yang; Lian-Feng Zhang; Yan Zhang; Chen Liu; Peter P Liu; Qi-Zhu Tang; Ai-Bing Wang; Xiang Wei; Xue Bai; Zhou-Yan Bian; Manyin Chen; Yingjie Chen; John Fassett; Jinghua Feng; You-Wen He; Hongliang Li
Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3β and TGF-β1-Smad signalling.
Cardiovascular research 2011;92(1):85-94.
2011: Mei Sun; Manyin Chen; Youan Liu; Masahiro Fukuoka; Kim Zhou; Guohua Li; Fayez Dawood; Anthony Gramolini; Peter P Liu
Cathepsin-L contributes to cardiac repair and remodelling post-infarction.
Cardiovascular research 2011;89(2):374-83.
2010: Hongliang Li; Qi-Zhu Tang; Chen Liu; Mark Moon; Manyin Chen; Ling Yan; Zhou-Yan Bian; Yan Zhang; Ai-Bing Wang; Mai P Nghiem; Peter P Liu
Cellular FLICE-inhibitory protein protects against cardiac remodeling induced by angiotensin II in mice.
Hypertension 2010;56(6):1109-17.
2010: J He; Shuben Li; Wenlong Shao; Daoyuan Wang; Manyin Chen; W Yin; Wei Wang; Yingying Gu; Baoliang Zhong
Activated carbon nanoparticles or methylene blue as tracer during video-assisted thoracic surgery for lung cancer can help pathologist find the detected lymph nodes.
Journal of surgical oncology 2010;102(6):676-82.
2010: He Huang; Qi-Zhu Tang; Ai-Bing Wang; Manyin Chen; Ling Yan; Chen Liu; Hong Jiang; Qinglin Yang; Zhou-Yan Bian; Xue Bai; Li-Hua Zhu; Lang Wang; Hongliang Li
Tumor suppressor A20 protects against cardiac hypertrophy and fibrosis by blocking transforming growth factor-beta-activated kinase 1-dependent signaling.
Hypertension 2010;56(2):232-9.
2010: Yu Shi; Masahiro Fukuoka; Guohua Li; Youan Liu; Manyin Chen; Michael Konviser; Xin Chen; Mary Anne Opavsky; Peter P Liu
Regulatory T cells protect mice against coxsackievirus-induced myocarditis through the transforming growth factor beta-coxsackie-adenovirus receptor pathway.
Circulation 2010;121(24):2624-34.
2010: Manyin Chen; Wenlong Shao; Jianxing He; Daoyuan Wang
Role of pemetrexed and platinums combination in patients with non-small cell lung cancer.
Current drug targets 2010;11(1):29-36.
2009: J He; Shuben Li; Jun Liu; Yuan Qiu; Wenlong Shao; Hanzhang Chen; Manyin Chen; Wei Wang; Daoyuan Wang
Feasibility Of Administering Adjuvant Chemotherapy Of Pemetrexed Followed By Pemetrexed/oxaliplatin Immediately Post-VATS In Patients With Completely Resected NSCLC.
Journal of thoracic disease 2009;1(1):55-62.
2009: Jianxing He; Shuben Li; Wenlong Shao; Manyin Chen; Yingying Gu; Daoyuan Wang; Weiqiang Yin; Steven Tucker
Surgical Management Of 3 Cases With Huge Tracheoesophageal Fistula With Esophagus Segment in situ As Replacement Of The Posterior Membranous Wall Of The Trachea.
Journal of thoracic disease 2009;1(1):39-45.
2009: Yuichiro Maekawa; Nobuo Mizue; Annie Chan; Yu Shi; Youan Liu; Steven Dawood; Manyin Chen; Fayez Dawood; Geoffrey de Couto; Guo Hua Li; Nobutaka Suzuki; Wen-Chen Yeh; Anthony Gramolini; Jeffrey A Medin; Peter P Liu
Survival and cardiac remodeling after myocardial infarction are critically dependent on the host innate immune interleukin-1 receptor-associated kinase-4 signaling: a regulator of bone marrow-derived dendritic cells.
Circulation 2009;120(14):1401-14.
2009: Jianxing He; Manyin Chen; Wenlong Shao; Daoyuan Wang
Surgical management of huge tracheo-oesophageal fistula with oesophagus segment in situ as replacement of the posterior membranous wall of the trachea.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2009;36(3):600-2.
2009: Jianxing He; Xin Xu; Manyin Chen; Shuben Li; Weiqiang Yin; Susheng Wang; Yingying Gu
Novel method to repair tracheal defect by pectoralis major myocutaneous flap.
The Annals of thoracic surgery 2009;88(1):288-91.
2009: Guo Hua Li; Yu Shi; Yu Chen; Mei Sun; Sawsan Sader; Yuichiro Maekawa; Sara Arab; Fayez Dawood; Manyin Chen; Geoffrey De Couto; Youan Liu; Masahiro Fukuoka; Stanley Yang; Ming Da Shi; Lorrie A Kirshenbaum; Christopher A McCulloch; Peter Liu
Gelsolin regulates cardiac remodeling after myocardial infarction through DNase I-mediated apoptosis.
Circulation research 2009;104(7):896-904.
2009: Koji Higuchi; Bilal Ayach; Takeya SATO; Manyin Chen; Sean P Devine; Vanessa I Rasaiah; Fayez Dawood; Teruyuki Yanagisawa; Chuwa Tei; Toshihiro Takenaka; Peter P Liu; Jeffrey A Medin
Direct injection of kit ligand-2 lentivirus improves cardiac repair and rescues mice post-myocardial infarction.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(2):262-8.
2008: Hongliang Li; Chen Liu; Geoffrey de Couto; Maral Ouzounian; Mei Sun; Ai-Bing Wang; Yue Huang; Cheng-Wei He; Yu Shi; Xin Chen; Mai P Nghiem; Youan Liu; Manyin Chen; Fayez Dawood; Masahiro Fukuoka; Yuichiro Maekawa; Liyong Zhang; Andrew Leask; Asish K Ghosh; Lorrie A Kirshenbaum; Peter P Liu
Curcumin prevents and reverses murine cardiac hypertrophy.
The Journal of clinical investigation 2008;118(3):879-93.
2007: Keiji Kuba; Liyong Zhang; Yumiko Imai; Sara Arab; Manyin Chen; Yuichiro Maekawa; Michael Leschnik; Andreas Leibbrandt; Mato Markovic; Mato Makovic; Julia Schwaighofer; Nadine Beetz; Renata Musialek; G Greg Neely; Vukoslav Komnenovic; Ursula Kolm; Bernhard Metzler; Romeo Ricci; Hiromitsu Hara; Arabella Meixner; Mai Nghiem; Xin Chen; Fayez Dawood; Kit Man Wong; Renu Sarao; Eva Cukerman; Akinori Kimura; Lutz Hein; Johann G Thalhammer; Peter P Liu; Josef M Penninger
Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload.
Circulation research 2007;101(4):e32-42.
2007: Mei Sun; Manyin Chen; Fayez Dawood; Urszula Zurawska; Jeff Y Li; Thomas Parker; Zamaneh Kassiri; Lorrie A Kirshenbaum; Malcolm Arnold; Rama Khokha; Peter P Liu
Tumor necrosis factor-alpha mediates cardiac remodeling and ventricular dysfunction after pressure overload state.
Circulation 2007;115(11):1398-407.
2006: Makoto Yoshimitsu; Koji Higuchi; Fayez Dawood; Vanessa I Rasaiah; Bilal Ayach; Manyin Chen; Peter Liu; Jeffrey A Medin
Correction of cardiac abnormalities in fabry mice by direct intraventricular injection of a recombinant lentiviral vector that engineers expression of alpha-galactosidase A.
Circulation journal : official journal of the Japanese Circulation Society 2006;70(11):1503-8.
2006: Bilal Ayach; Makoto Yoshimitsu; Fayez Dawood; Mei Sun; Sara Arab; Manyin Chen; Koji Higuchi; Christopher Siatskas; Paul Lee; Hilda Lim; Jane Zhang; Eva Cukerman; William L Stanford; Jeffrey A Medin; Peter P Liu
Stem cell factor receptor induces progenitor and natural killer cell-mediated cardiac survival and repair after myocardial infarction.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2304-9.