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Nanhua Chen

Research Profile

Chemicals & Drugs

Physiology

Disorders

Falciparum Malaria

Genes & Molecular Sequences

Concepts & Ideas

Molecular Sequence Data

Procedures

Reverse Transcriptase Polymerase Chain Reaction

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Publications

TOP 3
Franka Teuscher; Michelle L Gatton; Nanhua Chen; Jennifer Peters; Dennis E Kyle; Qin Cheng
Artemisinin‐induced dormancy in plasmodium falciparum: duration, recovery rates, and implications in treatment failure.
Nanhua Chen; Marina Chavchich; Jennifer M Peters; Dennis E Kyle; Michelle L Gatton; Qin Cheng
Deamplification of pfmdr1-containing amplicon on chromosome 5 in Plasmodium falciparum is associated with reduced resistance to artelinic acid in vitro.
Marina Chavchich; Lucia Gerena; Jennifer Peters; Nanhua Chen; Qin Cheng; Dennis E Kyle
Role of pfmdr1 amplification and expression in induction of resistance to artemisinin derivatives in Plasmodium falciparum.

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All Publications

2010: Franka Teuscher; Michelle L Gatton; Nanhua Chen; Jennifer Peters; Dennis E Kyle; Qin Cheng
Artemisinin‐induced dormancy in plasmodium falciparum: duration, recovery rates, and implications in treatment failure.
The Journal of infectious diseases 2010;202(9):1362-8.
2010: Nanhua Chen; Marina Chavchich; Jennifer M Peters; Dennis E Kyle; Michelle L Gatton; Qin Cheng
Deamplification of pfmdr1-containing amplicon on chromosome 5 in Plasmodium falciparum is associated with reduced resistance to artelinic acid in vitro.
Antimicrobial agents and chemotherapy 2010;54(8):3395-401.
2010: Marina Chavchich; Lucia Gerena; Jennifer Peters; Nanhua Chen; Qin Cheng; Dennis E Kyle
Role of pfmdr1 amplification and expression in induction of resistance to artemisinin derivatives in Plasmodium falciparum.
Antimicrobial agents and chemotherapy 2010;54(6):2455-64.
2010: Joanne Baker; Mei-Fong Ho; Anita Pelecanos; Michelle L Gatton; Nanhua Chen; Salim Abdullah; Audrey Albertini; Frederic Ariey; John Barnwell; David Bell; Jane Cunningham; Djibrine Djalle; Diego F Echeverry; Dionicia Gamboa; Jeffery Hii; Myat Phone Kyaw; Jennifer Luchavez; Christopher Membi; Didier Menard; Claribel Murillo; Sina Nhem; Bernhards Ogutu; Pamela Onyor; Wellington Oyibo; Shan Qing Wang; James McCarthy; Qin Cheng
Global sequence variation in the histidine-rich proteins 2 and 3 of Plasmodium falciparum: implications for the performance of malaria rapid diagnostic tests.
Malaria journal 2010;9():129.
2009: Jacqueline A Upcroft; Kenia G Krauer; Anita G Burgess; Linda A Dunn; Nanhua Chen; Peter Upcroft
Sequence map of the 3-Mb Giardia duodenalis assemblage A chromosome.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2009;17(8):1001-14.
2008: Nanhua Chen; Qi Gao; Shanqing Wang; Guangze Wang; Michelle L Gatton; Qin Cheng
No genetic bottleneck in Plasmodium falciparum wild-type Pfcrt alleles reemerging in Hainan Island, China, following high-level chloroquine resistance.
Antimicrobial agents and chemotherapy 2008;52(1):345-7.
2007: Nanhua Chen; Alyson Auliff; Karl Rieckmann; Michelle L Gatton; Qin Cheng
Relapses of Plasmodium vivax infection result from clonal hypnozoites activated at predetermined intervals.
The Journal of infectious diseases 2007;195(7):934-41.
2006: Alyson Auliff; Danny W Wilson; Bruce Russell; Qi Gao; Nanhua Chen; Le Ngoc Anh; Jason Maguire; David Bell; Michael T O'Neil; Qin Cheng
Amino acid mutations in Plasmodium vivax DHFR and DHPS from several geographical regions and susceptibility to antifolate drugs.
The American journal of tropical medicine and hygiene 2006;75(4):617-21.
2006: Elizabeth V Fowler; Marina Chavchich; Nanhua Chen; Jennifer M Peters; Dennis E Kyle; Michelle L Gatton; Qin Cheng
Physical linkage to drug resistance genes results in conservation of var genes among West Pacific Plasmodium falciparum isolates.
The Journal of infectious diseases 2006;194(7):939-48.
2006: Michelle L Gatton; Jennifer M Peters; Karryn Gresty; Elizabeth V Fowler; Nanhua Chen; Qin Cheng
Detection sensitivity and quantitation of Plasmodium falciparum var gene transcripts by real-time RT-PCR in comparison with conventional RT-PCR.
The American journal of tropical medicine and hygiene 2006;75(2):212-8.
2005: Nanhua Chen; Danny W Wilson; Cielo Pasay; David Bell; Laura B Martin; Dennis Kyle; Qin Cheng
Origin and dissemination of chloroquine-resistant Plasmodium falciparum with mutant pfcrt alleles in the Philippines.
Antimicrobial agents and chemotherapy 2005;49(5):2102-5.
2004: Michael L J Korsinczky; Katja Fischer; Nanhua Chen; Joanne Baker; Karl H Rieckmann; Qin Cheng
Sulfadoxine resistance in Plasmodium vivax is associated with a specific amino acid in dihydropteroate synthase at the putative sulfadoxine-binding site.
Antimicrobial agents and chemotherapy 2004;48(6):2214-22.
2003: Nanhua Chen; Dennis E Kyle; Cielo Pasay; Elizabeth V Fowler; Joanne Baker; Jennifer M Peters; Qin Cheng
pfcrt Allelic types with two novel amino acid mutations in chloroquine-resistant Plasmodium falciparum isolates from the Philippines.
Antimicrobial agents and chemotherapy 2003;47(11):3500-5.
2002: Jennifer Peters; Elizabeth V Fowler; Michelle L Gatton; Nanhua Chen; Allan Saul; Qin Cheng
High diversity and rapid changeover of expressed var genes during the acute phase of Plasmodium falciparum infections in human volunteers.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10689-94.
2002: Jennifer M Peters; Nanhua Chen; Michelle L Gatton; Michael L J Korsinczky; Elizabeth V Fowler; Sergio Manzetti; Allan Saul; Qin Cheng
Mutations in cytochrome b resulting in atovaquone resistance are associated with loss of fitness in Plasmodium falciparum.
Antimicrobial agents and chemotherapy 2002;46(8):2435-41.
2002: Nanhua Chen; Joanne Baker; Nadine Ezard; Matthew Burns; Michael D Edstein; Qin Cheng
Short report: Molecular evaluation of the efficacy of chloroquine treatment of uncomplicated Plasmodium falciparum malaria in East Timor.
The American journal of tropical medicine and hygiene 2002;67(1):64-6.
2002: Elizabeth V Fowler; Jennifer M Peters; Michelle L Gatton; Nanhua Chen; Qin Cheng
Genetic diversity of the DBLalpha region in Plasmodium falciparum var genes among Asia-Pacific isolates.
Molecular and biochemical parasitology 2002;120(1):117-26.
2001: Nanhua Chen; Bruce Russell; J Staley; Barbara M Kotecka; Peter Nasveld; Qin Cheng
Sequence polymorphisms in pfcrt are strongly associated with chloroquine resistance in Plasmodium falciparum.
The Journal of infectious diseases 2001;183(10):1543-5.
2000: Michael L J Korsinczky; Nanhua Chen; Barbara M Kotecka; Allan Saul; Karl H Rieckmann; Qin Cheng
Mutations in Plasmodium falciparum cytochrome b that are associated with atovaquone resistance are located at a putative drug-binding site.
Antimicrobial agents and chemotherapy 2000;44(8):2100-8.