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Pei-Jer Chen

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Tung-Hung Su; Te-Tien Ting; Tai-Chung Tseng; Chi-Ling Chen; Pei-Jer Chen; Jia-Horng Kao; Chen-Hua Liu; Chun-Jen Liu; Ding-Shinn Chen
Serum microRNA-122 level correlates with virologic responses to pegylated interferon therapy in chronic hepatitis C.
Biao Liu; Di Liu; Jing Liu; Min Wang; Xiaowen Wang; Dongliang Yang; Dianyuan Zhao; Pei-Jer Chen; Fuchu He; Li Tang
Liver sinusoidal endothelial cell lectin inhibits CTL-dependent virus clearance in mouse models of viral hepatitis.
Hong-Yuan Hsu; Yung-Ming Jeng; Yen-Hsuan Ni; Jia-Feng Wu; Mei-Hwei Chang; Huey-Ling Chen; Cheng-Lun Chiang; Pei-Jer Chen
Long-term follow-up of children with postnatal immunoprophylaxis failure who were infected with hepatitis B virus surface antigen gene mutant.

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2013: Tung-Hung Su; Te-Tien Ting; Tai-Chung Tseng; Chi-Ling Chen; Pei-Jer Chen; Jia-Horng Kao; Chen-Hua Liu; Chun-Jen Liu; Ding-Shinn Chen
Serum microRNA-122 level correlates with virologic responses to pegylated interferon therapy in chronic hepatitis C.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(19):7844-9.
2013: Biao Liu; Di Liu; Jing Liu; Min Wang; Xiaowen Wang; Dongliang Yang; Dianyuan Zhao; Pei-Jer Chen; Fuchu He; Li Tang
Liver sinusoidal endothelial cell lectin inhibits CTL-dependent virus clearance in mouse models of viral hepatitis.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(8):4185-95.
2013: Hong-Yuan Hsu; Yung-Ming Jeng; Yen-Hsuan Ni; Jia-Feng Wu; Mei-Hwei Chang; Huey-Ling Chen; Cheng-Lun Chiang; Pei-Jer Chen
Long-term follow-up of children with postnatal immunoprophylaxis failure who were infected with hepatitis B virus surface antigen gene mutant.
The Journal of infectious diseases 2013;207(7):1047-57.
2013: Wei-Hsiang Lin; Aisuke Nii; Wan-Jen Yang; Kun-Huei Yeh; Shiou-Hwei Yeh; Stanley Shi-Chung Chang; Toshiyoshi Fujiwara; Pei-Jer Chen
Telomerase-specific oncolytic adenoviral therapy for orthotopic hepatocellular carcinoma in HBx transgenic mice.
International journal of cancer. Journal international du cancer 2013;132(6):1451-62.
2013: Joong-Won Park; Ronnie T Poon; Chee-Kiat Tan; Tawesak Tanwandee; Gaojun Teng; Deepak Amarapurkar; Yee Chao; Pei-Jer Chen; Jean-Francois H Geschwind; Khean-Lee Goh; Kwang-Hyub Han; Masatoshi Kudo; Han Chu Lee; Rheun-Chuan Lee; Laurentius A Lesmana; Ho Yeong Lim; Seung Woon Paik; Ann-Lii Cheng
Consensus recommendations and review by an International Expert Panel on Interventions in Hepatocellular Carcinoma (EPOIHCC).
Liver international : official journal of the International Association for the Study of the Liver 2013;33(3):327-37.
2013: Hung-Chih Yang; Ming-Lung Yu; Chi-Ling Chen; Ding-Shinn Chen; Pei-Jer Chen; Wan-Long Chuang; Chia-Yen Dai; Chen-Hua Liu; Chun-Jen Liu; Cheng-Yuan Peng; Yueh-Chi Shen; Tung-Hung Su; Tai-Chung Tseng; Jia-Horng Kao
Distinct evolution and predictive value of hepatitis B virus precore and basal core promoter mutations in interferon-induced hepatitis B e antigen seroconversion.
Hepatology (Baltimore, Md.) 2013;57(3):934-43.
2013: Yi-Chun Yeh; Pei-Jer Chen; Mei-Shu Lai
Antiviral therapy and hepatitis B virus-related hepatocellular carcinoma recurrence.
JAMA : the journal of the American Medical Association 2013;309(8):765-6.
2013: Kuen-Feng Chen; Pei-Jer Chen; Hui-Ling Chen; Pei-Yi Chu; Kimihisa Ichikawa; Chun-Yu Liu; Chung-Wai Shiau; Wei-Tien Tai; Ann-Lii Cheng
Sorafenib and its derivative SC-49 sensitize hepatocellular carcinoma cells to CS-1008, a humanized anti-TNFRSF10B (DR5) antibody.
British journal of pharmacology 2013;168(3):658-72.
2013: Tai-Chung Tseng; Chia-Chi Wang; Hung-Chih Yang; Stephanie Fang-Tzu Kuo; Chi-Ling Chen; Ding-Shinn Chen; Pei-Jer Chen; Cheng-An Hsu; Chen-Hua Liu; Chun-Jen Liu; Tung-Hung Su; Jia-Horng Kao
Serum hepatitis B surface antigen levels help predict disease progression in patients with low hepatitis B virus loads.
Hepatology (Baltimore, Md.) 2013;57(2):441-50.
2013: Han Chong Toh; Peter Ansell; Dawn M Carlson; Brian I Carr; Pei-Jer Chen; Barry Dowell; Sharlene Gill; Jennifer J Knox; Evelyn M McKeegan; Michelle Pedersen; Jiang Qian; Qin Qin; Justin L Ricker; Frank Scappaticci; Wei Peng Yong
Phase 2 trial of linifanib (ABT-869) in patients with unresectable or metastatic hepatocellular carcinoma.
Cancer 2013;119(2):380-7.
2013: Yixin Chen; Tong Cheng; Shengxiang Ge; Delei He; Chuan Li; James Wai-Kuo Shih; Jun Zhang; Qinjian Zhao; Pei-Jer Chen; Ningshao Xia
Antigenic analysis of divergent genotypes human Enterovirus 71 viruses by a panel of neutralizing monoclonal antibodies: current genotyping of EV71 does not reflect their antigenicity.
Vaccine 2013;31(2):425-30.
2013: Charles Balabaud; Wesal R Al-Rabih; Pei-Jer Chen; Kimberley Evason; Linda Ferrell; Juan C Hernandez-Prera; Shiu-Feng Huang; Brigitte Le Bail; Thomas Longerich; Young Nyun Park; Alberto Quaglia; Peter Schirmacher; Christine Sempoux; Swan N Thung; Michael Torbenson; Aileen Wee; Matthew M Yeh; Shiou-Hwei Yeh; Jessica Zucman-Rossi; Paulette Bioulac-Sage
Focal Nodular Hyperplasia and Hepatocellular Adenoma around the World Viewed through the Scope of the Immunopathological Classification.
International journal of hepatology 2013;2013():268625.
2013: Chen-Chi Wu; Wei-Shiung Yang; Pei-Jer Chen; Chuan-Jen Hsu; YH Lin; Ying-Chang Lu; Pei-Lung Chen
Application of massively parallel sequencing to genetic diagnosis in multiplex families with idiopathic sensorineural hearing impairment.
PloS one 2013;8(2):e57369.
2013: Tung-Hung Su; Tai-Chung Tseng; Hung-Chih Yang; Chi-Ling Chen; Pei-Jer Chen; Jia-Horng Kao; Chen-Hua Liu; Chun-Jen Liu; Ding-Shinn Chen
Longitudinal change of HBsAg in HBeAg-negative patients with genotype B or C infection.
PloS one 2013;8(2):e55916.
2013: Ting-Shuo Huang; Li-Mei Lin; Chia-Ying Lo; Yu-Chiau Shyu; Shin-Sheng Yuan; Huang-Yang Chen; Pei-Jer Chen
Effect of parenteral selenium supplementation in critically ill patients: a systematic review and meta-analysis.
PloS one 2013;8(1):e54431.
2013: Pei-Jer Chen; T-C Wu
One step closer to an experimental infection system for Hepatitis B Virus? --- the identification of sodium taurocholate cotransporting peptide as a viral receptor.
Cell & bioscience 2013;3(1):2.
2013: Quan Yuan; Jun Zhang; Yan Yan; Ding-Shinn Chen; Pei-Jer Chen; Sheng-xiang Ge; Cheng-Hao Huang; Jia-Horng Kao; Zhuo Li; Chun-Jen Liu; Ping-Guo Liu; Cheng-Yuan Peng; Liu-Wei Song; Ying-Bin Wang; Ning-Shao Xia
Quantitative hepatitis B core antibody level may help predict treatment response in chronic hepatitis B patients.
Gut 2013;62(1):182-4.
2012: Chun-Yi Lu; Pei-Lan Shao; Ning-Shao Xia; Luan-Yin Chang; Pei-Jer Chen; Li-Min Huang
A highly specific ELISA for diagnosis of 2009 influenza A (H1N1) virus infections.
Journal of the Formosan Medical Association = Taiwan yi zhi 2012;111(12):693-7.
2012: Wei-Liang Shih; Hung-Chuen Chang; Pei-Jer Chen; Shou-Dong Lee; Yun-Fan Liaw; Chih-Lin Lin; Shi-Ming Lin; Chun-Jen Liu; Ming-Whei Yu
Influences of tobacco and alcohol use on hepatocellular carcinoma survival.
International journal of cancer. Journal international du cancer 2012;131(11):2612-21.
2012: Tai-Chung Tseng; Chia-Chi Wang; Hung-Chih Yang; Chi-Ling Chen; Ding-Shinn Chen; Pei-Jer Chen; Stephanie Fang-Tzu Kuo; Chen-Hua Liu; Chun-Jen Liu; Tung-Hung Su; Jia-Horng Kao
Young chronic hepatitis B patients with nucleos(t)ide analogue-induced hepatitis B e antigen seroconversion have a higher risk of HBV reactivation.
The Journal of infectious diseases 2012;206(10):1521-31.
2012: Jung-Chen Su; Wei-Tien Tai; Kuen-Feng Chen; Pei-Jer Chen; Wei-Lin Chen; Jui-Wen Huang; Inki Kim; Chun-Yu Liu; Chung-Wai Shiau
Synthesis and biological activity of obatoclax derivatives as novel and potent SHP-1 agonists.
European journal of medicinal chemistry 2012;56():127-33.
2012: Jia-Horng Kao; Chun-Jen Liu; Ding-Shinn Chen; Pei-Jer Chen; Guey-Mei Jow; Bing-Fang Chen
Fine mapping of hepatitis B virus pre-S deletion and its association with hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver 2012;32(9):1373-81.
2012: Cheng-Hao Huang; Ping-Guo Liu; Chang-Rong Chen; Pei-Jer Chen; Yi-Xin Chen; Sheng-xiang Ge; Yu Xue; Shiou-Hwei Yeh; Hai Yu; Quan Yuan; Jun Zhang; Ya-Li Zhang; Qing-Bing Zheng; Ning-Shao Xia
Influence of mutations in hepatitis B virus surface protein on viral antigenicity and phenotype in occult HBV strains from blood donors.
Journal of hepatology 2012;57(4):720-9.
2012: Kuen-Feng Chen; Pei-Jer Chen; Cheng-Yi Hsu; Jui-Wen Huang; InKi Kim; Chun-Yu Liu; Wei-Tien Tai; Chung-Wai Shiau
Blockade of STAT3 activation by sorafenib derivatives through enhancing SHP-1 phosphatase activity.
European journal of medicinal chemistry 2012;55():220-7.
2012: Yi-Jiun Lin; Hui-Lin Wu; Ding-Shinn Chen; Pei-Jer Chen
Hepatitis B virus nucleocapsid but not free core antigen controls viral clearance in mice.
Journal of virology 2012;86(17):9266-73.
2012: Nezam H Afdhal; Angelo Andriulli; Andres Brainsky; Fiona Campbell; Pei-Jer Chen; Edoardo G Giannini; Kwang-Hyub Han; Denise Hyde; Lennox Jeffers; Jin-Woo Lee; John McHutchison; Aftab Mohsin; Ghias Tayyab; Dickens Theodore
Eltrombopag before procedures in patients with cirrhosis and thrombocytopenia.
The New England journal of medicine 2012;367(8):716-24.
2012: Kuen-Feng Chen; Pei-Jer Chen; Jing-Ping Lin; Chun-Yu Liu; Chung-Wai Shiau; Wei-Tien Tai; Hui-Chuan Yu; Ann-Lii Cheng
Inhibition of Bcl-2 improves effect of LCL161, a SMAC mimetic, in hepatocellular carcinoma cells.
Biochemical pharmacology 2012;84(3):268-77.
2012: Po-Jen Chen; Hsuan-Cheng Huang; Chen-Ching Lin; Wan-Hsin Liu; Shiou-Hwei Yeh; Chi-Ling Chen; Ding-Shinn Chen; Pei-Jer Chen
Androgen pathway stimulates microRNA-216a transcription to suppress the tumor suppressor in lung cancer-1 gene in early hepatocarcinogenesis.
Hepatology (Baltimore, Md.) 2012;56(2):632-43.
2012: Ming-Jen Lin; Pei-Jer Chen; Ming-Ching Luoh
HBeAg(+) and sex ratio of offspring: evidence form Taiwan's three million newborns.
American journal of human biology : the official journal of the Human Biology Council 2012;24(4):541-4.
2012: Tai-Chung Tseng; Chia-Chi Wang; Hung-Chih Yang; Chi-Ling Chen; Ding-Shinn Chen; Pei-Jer Chen; Stephanie Fang-Tzu Kuo; Chen-Hua Liu; Chun-Jen Liu; Tung-Hung Su; Jia-Horng Kao
High levels of hepatitis B surface antigen increase risk of hepatocellular carcinoma in patients with low HBV load.
Gastroenterology 2012;142(5):1140-1149.e3; quiz e13-4.
2012: Sheng-Han Wang; Ning-Shao Xia; Kun-Huei Yeh; Shiou-Hwei Yeh; Quan Yuan; Ding-Shinn Chen; Wei-Hsiang Lin; Pei-Jer Chen
Estrogen receptor α represses transcription of HBV genes via interaction with hepatocyte nuclear factor 4α.
Gastroenterology 2012;142(4):989-998.e4.
2012: Kuen-Feng Chen; Pei-Jer Chen; Kimihisa Ichikawa; Chun-Yu Liu; Wei-Tien Tai; Hui-Ling Chen; Ann-Lii Cheng
Dovitinib sensitizes hepatocellular carcinoma cells to TRAIL and tigatuzumab, a novel anti-DR5 antibody, through SHP-1-dependent inhibition of STAT3.
Biochemical pharmacology 2012;83(6):769-77.
2012: Wang-Huei Sheng; Sui-Yuan Chang; Mao-Yuan Chen; Pei-Jer Chen; Szu-Min Hsieh; Chien-Ching Hung; Jia-Horng Kao; Chun-Jen Liu; Shan-Chwen Chang
Differential clinical and virologic impact of hepatitis B virus genotypes B and C on HIV-coinfected patients receiving lamivudine-containing highly active antiretroviral therapy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2012;54(4):548-55.
2012: Wei-Tien Tai; Pei-Jer Chen; Ann-Lii Cheng; Ching-Huai Ko; Mai-Wei Lin; Chun-Yu Liu; Chung-Wai Shiau; Kuen-Feng Chen
Dovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3.
Molecular cancer therapeutics 2012;11(2):452-63.
2012: Suzhen Jiang; W Li; Xiaojun Li; Malcolm A McCrae; Yongfeng Wang; Chunhui Xu; Ziwei Yang; Jiangbo Zhang; Hui Zhuang; Pei-Jer Chen; Xiangmei Chen; Jinlin Hou; Fengmin Lu
Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis.
PloS one 2012;7(9):e40363.
2012: Chen-Hua Liu; Chun-Jen Liu; Tung-Hung Su; Tai-Chung Tseng; Sheng-Shun Yang; Ding-Shinn Chen; Jun-Herng Chen; Pei-Jer Chen; Cheng-Chao Liang; Chih-Lin Lin; Jou-Wei Lin; Jia-Horng Kao
Interleukin 28B genetic polymorphisms play a minor role in identifying optimal treatment duration in HCV genotype 1 slow responders to pegylated interferon plus ribavirin.
Antiviral therapy 2012;17(6):1059-67.
2012: Horng-Tay Tzeng; Lieping Chen; Pei-Jer Chen; Hsiu-Jung Liao; Yi-Jiun Lin; Hwei-Fang Tsai; Ping-Ning Hsu
PD-1 blockage reverses immune dysfunction and hepatitis B viral persistence in a mouse animal model.
PloS one 2012;7(6):e39179.
2012: Chen-Hua Liu; Chun-Jen Liu; Tung-Hung Su; Tai-Chung Tseng; Sheng-Shun Yang; Ding-Shinn Chen; Jun-Herng Chen; Pei-Jer Chen; Shih-Jer Hsu; Cheng-Chao Liang; Chih-Lin Lin; Jou-Wei Lin; Jia-Horng Kao
Interleukin 28B genetic polymorphisms and viral factors help identify HCV genotype-1 patients who benefit from 24-week pegylated interferon plus ribavirin therapy.
Antiviral therapy 2012;17(3):477-84.
2012: Chia-Chieh Hsiao; Wan-Hsin Liu; Jeng-You Wu; Juliana Chang; Pei-Jer Chen; Shih-Yun Han; Shiou-Hwei Yeh
High-resolution melting and real-time PCR for quantification and detection of drug-resistant HBV mutants in a single amplicon.
Antiviral therapy 2012;17(2):291-303.
2012: Li-Tzong Chen; Miin-Fu Chen; Pei-Jer Chen; Yaw-Sen Chen; Chin-Fu Hsiao; Long-Bin Jeng; Po-Huang Lee; Wei-Chen Lee; Lung-An Li; Deng-Yn Lin; Wing-Yui Lui; King-Tong Mok; Jacqueline Whang-Peng; Cheng-Chung Wu; Gar-Yang Chau; Chao-Long Chen
Long-term results of a randomized, observation-controlled, phase III trial of adjuvant interferon Alfa-2b in hepatocellular carcinoma after curative resection.
Annals of surgery 2012;255(1):8-17.
2011: Er-Yea Wang; Kun-Huei Yeh; Shiou-Hwei Yeh; Pei-Jer Chen; Wei-Chih Chen; Hsiang-Po Huang; Yung-Ming Jeng; Wei-Hsiang Lin; Ting-Fen Tsai; Ding-Shinn Chen
Depletion of β-catenin from mature hepatocytes of mice promotes expansion of hepatic progenitor cells and tumor development.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(45):18384-9.
2011: Yu-Yun Shao; Pei-Jer Chen; Yea-Hui Ding; Chih-Hung Hsu; Chien-Chung Huang; Ying-Hui Lee; Zhong-Zhe Lin; Ann-Lii Cheng
Impact of baseline hepatitis B viral DNA levels on survival of patients with advanced hepatocellular carcinoma.
Anticancer research 2011;31(11):4007-11.
2011: Thomas Yau; A Benjamin Suttle; Pierre Chan; Pei-Jer Chen; C Martin Curtis; Mohammed M Dar; Jennifer Gauvin; Jeffrey P Hodge; Philip S Murphy; Ronnie T Poon
Phase I dose-finding study of pazopanib in hepatocellular carcinoma: evaluation of early efficacy, pharmacokinetics, and pharmacodynamics.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(21):6914-23.
2011: Wan-Hsin Liu; Shiou-Hwei Yeh; Pei-Jer Chen
Role of microRNAs in hepatitis B virus replication and pathogenesis.
Biochimica et biophysica acta 2011;1809(11-12):678-85.
2011: Wei-Tien Tai; Pei-Jer Chen; Ann-Lii Cheng; Hsiang-Po Huang; Jui-Wen Huang; Chung-Wai Shiau; Kuen-Feng Chen
Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma.
Journal of hepatology 2011;55(5):1041-8.
2011: C-J Liu; T-C Tseng; Z-L Wang; C-H Liu; C-L Chen; D-S Chen; Pei-Jer Chen; T-C Chen; H-R Cheng; J-H Kao
Effects of hepatitis B virus precore and basal core promoter mutations on the expression of viral antigens: genotype B vs C.
Journal of viral hepatitis 2011;18(10):e482-90.
2011: Yone-Han Mah; Ming-Yang Lai; Chen-Hua Liu; Chun-Jen Liu; Ding-Shinn Chen; Pei-Jer Chen; Ching-Sheng Hsu; Jia-Horng Kao
Serum p53 gene polymorphisms and severity of hepatitis B or C-related chronic liver diseases in Taiwan.
Hepatology international 2011;5(3):814-21.
2011: Tai-Chung Tseng; Chia-Chi Wang; Chun-Jen Liu; Tung-Hung Su; Chi-Ling Chen; Ding-Shinn Chen; Pei-Jer Chen; Jia-Horng Kao
Serum hepatitis B surface antigen levels predict surface antigen loss in hepatitis B e antigen seroconverters.
Gastroenterology 2011;141(2):517-25, 525.e1-2.
2011: Dasheng Lee; Shiou-Hwei Yeh; Pei-Jer Chen; Wen Pin Chou; Ping Hei Chen
DNA detection using commercial mobile phones.
Biosensors & bioelectronics 2011;26(11):4349-54.
2011: Kuen-Feng Chen; Pei-Jer Chen; Wei-Lin Chen; Ann-Lii Cheng; Cheng-Yi Hsu; Jui-Wen Huang; Wei-Tien Tai; Chung-Wai Shiau
Sorafenib derivatives induce apoptosis through inhibition of STAT3 independent of Raf.
European journal of medicinal chemistry 2011;46(7):2845-51.
2011: Hwai-I Yang; Man-Fung Yuen; Sang-Hoon Ahn; Henry Lik-Yuen Chan; Chien-Jen Chen; Pei-Jer Chen; Kwang-Hyub Han; Do-Young Kim; Wai-Kay Seto; Vincent Wai-Sun Wong
Risk estimation for hepatocellular carcinoma in chronic hepatitis B (REACH-B): development and validation of a predictive score.
The lancet oncology 2011;12(6):568-74.
2011: Chen-Hua Liu; Cheng-Chao Liang; Kai-Wen Huang; Chun-Jen Liu; Shih-I Chen; Jou-Wei Lin; Peir-Haur Hung; Hung-Bin Tsai; Ming-Yang Lai; Pei-Jer Chen; Jun-Herng Chen; Ding-Shinn Chen; Jia-Horng Kao
Transient elastography to assess hepatic fibrosis in hemodialysis chronic hepatitis C patients.
Clinical journal of the American Society of Nephrology : CJASN 2011;6(5):1057-65.
2011: Kuen-Feng Chen; Hui-Chuan Yu; Chun-Yu Liu; Hui-Ju Chen; Yi-Ching Chen; Duen-Ren Hou; Pei-Jer Chen; Ann-Lii Cheng
Bortezomib sensitizes HCC cells to CS-1008, an antihuman death receptor 5 antibody, through the inhibition of CIP2A.
Molecular cancer therapeutics 2011;10(5):892-901.
2011: Kuen-Feng Chen; Hui-Ling Chen; Wei-Tien Tai; Wen-Chi Feng; Chih-Hung Hsu; Pei-Jer Chen; Ann-Lii Cheng
Activation of phosphatidylinositol 3-kinase/Akt signaling pathway mediates acquired resistance to sorafenib in hepatocellular carcinoma cells.
The Journal of pharmacology and experimental therapeutics 2011;337(1):155-61.
2011: Ching-Sheng Hsu; Shih-Jer Hsu; Hung-Chia Chen; Tai-Chung Tseng; Chen-Hua Liu; Wei-Fang Niu; Jenher Jeng; Chun-Jen Liu; Ming-Yang Lai; Pei-Jer Chen; Jia-Horng Kao; Ding-Shinn Chen
Association of IL28B gene variations with mathematical modeling of viral kinetics in chronic hepatitis C patients with IFN plus ribavirin therapy.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(9):3719-24.
2011: T-H Su; Pei-Jer Chen; Tze-Chien Chen; H-R Cheng; L Li; Kuo-Sin Lin; Jia-Horng Kao; Ding-Shinn Chen; Chun-Jen Liu
The clinical significance of occult hepatitis B transfusion in Taiwan--a look-back study.
Transfusion medicine (Oxford, England) 2011;21(1):33-41.
2011: Ji-Rong Yang; Chun-Hui Su; Ho-Sheng Wu; Feng-Yee Chang; Pei-Jer Chen; Li-Ching Hsu; Yuan-Pin Huang; Yu-Cheng Lin; Ming-Tsan Liu
New variants and age shift to high fatality groups contribute to severe successive waves in the 2009 influenza pandemic in Taiwan.
PloS one 2011;6(11):e28288.
2011: Tai-Chung Tseng; Sheng-Shun Yang; Ming-Lung Yu; Ding-Shinn Chen; Pei-Jer Chen; Ching-Sheng Hsu; Yi-Wen Huang; Stephanie Fang-Tzu Kuo; Chih-Lin Lin; Chen-Hua Liu; Chun-Jen Liu; Corinna Jen-Hui Pan; Chien-Wei Su; Jia-Horng Kao
Effect of host and viral factors on hepatitis B e antigen-positive chronic hepatitis B patients receiving pegylated interferon-α-2a therapy.
Antiviral therapy 2011;16(5):629-37.
2011: Ying-Chang Lu; Wen-Sheng Shen; Jau-Min Wong; Chen-Chi Wu; Ting-Hua Yang; Te-Huei Yeh; I-Shing Yu; Qing Chang; Pei-Jer Chen; Shu-Wha Lin; Xi Lin; Chuan-Jen Hsu
Establishment of a knock-in mouse model with the SLC26A4 c.919-2A>G mutation and characterization of its pathology.
PloS one 2011;6(7):e22150.
2011: Ming-Lun Yeh; Ming-Lung Yu; Pei-Jer Chen; Wan-Long Chuang; Chia-Yen Dai; Tsung-Hui Hu; Jee-Fu Huang; Chao-Hung Hung; Jia-Horng Kao; Chuan-Mo Lee; Zu-Yau Lin; Chun-Jen Liu; Sheng-Nan Lu; Jing-Houng Wang; Ding-Shinn Chen
Long-term effect of interferon plus ribavirin on hepatitis B surface antigen seroclearance in patients dually infected with hepatitis B and C viruses.
PloS one 2011;6(6):e20752.
2011: Shih-Jer Hsu; Ching-Sheng Hsu; Chen-Hua Liu; Chun-Jen Liu; Chi-Ling Chen; Pei-Jer Chen; Ding-Shinn Chen; Jia-Horng Kao
HCV core gene polymorphisms correlate with liver fibrosis but not sustained virological response in patients with genotype 1 infection.
Antiviral therapy 2011;16(2):227-35.
2011: Wen Pin Chou; Ping Hei Chen; Ming Miao; Long Sheng Kuo; Shiou-Hwei Yeh; Pei-Jer Chen
Rapid DNA amplification in a capillary tube by natural convection with a single isothermal heater.
BioTechniques 2011;50(1):52-7.
2011: Hsuan-Hao Huang; Wei-Liang Shih; Yi-Hsiu Li; Chih-Feng Wu; Pei-Jer Chen; Chih-Lin Lin; Chun-Jen Liu; Yun-Fan Liaw; Shi-Ming Lin; Shou-Dong Lee; Ming-Whei Yu
Hepatitis B viraemia: its heritability and association with common genetic variation in the interferon gamma signalling pathway.
Gut 2011;60(1):99-107.
2010: Kuen-Feng Chen; C-Y Liu; Y-C Lin; H-C Yu; T-H Liu; D-R Hou; Pei-Jer Chen; Ann-Lii Cheng
CIP2A mediates effects of bortezomib on phospho-Akt and apoptosis in hepatocellular carcinoma cells.
Oncogene 2010;29(47):6257-66.
2010: Kuen-Feng Chen; Wei-Tien Tai; Tsung-Hao Liu; Hsiang-Po Huang; Yu-Chin Lin; Chung-Wai Shiau; Pui-Kai Li; Pei-Jer Chen; Ann-Lii Cheng
Sorafenib overcomes TRAIL resistance of hepatocellular carcinoma cells through the inhibition of STAT3.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(21):5189-99.
2010: Pei-Jer Chen; Junji Furuse; Kwang-Hyub Han; Chiun Hsu; Ho-Yeong Lim; Hanlim Moon; Shukui Qin; Sheng-Long Ye; Ee-Min Yeoh; Winnie Yeo
Issues and controversies of hepatocellular carcinoma-targeted therapy clinical trials in Asia: experts' opinion.
Liver international : official journal of the International Association for the Study of the Liver 2010;30(10):1427-38.
2010: Mei-Hsuan Lee; Hwai-I Yang; Sheng-Nan Lu; Chin-Lan Jen; Shiou-Hwei Yeh; Chun-Jen Liu; Pei-Jer Chen; San-Lin You; Li-Yu Wang; Wei J Chen; Chien-Jen Chen
Hepatitis C virus seromarkers and subsequent risk of hepatocellular carcinoma: long-term predictors from a community-based cohort study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(30):4587-93.
2010: Chen-Hua Liu; Cheng-Chao Liang; Chun-Jen Liu; Jou-Wei Lin; Shih-I Chen; Peir-Haur Hung; Hung-Bin Tsai; Ming-Yang Lai; Pei-Jer Chen; Ding-Shinn Chen; Jia-Horng Kao
Pegylated interferon alfa-2a monotherapy for hemodialysis patients with acute hepatitis C.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2010;51(5):541-9.
2010: Kai-Wen Huang; Hui-Lin Wu; Hsiu-Lin Lin; Po-Chin Liang; Pei-Jer Chen; Shih-Hui Chen; Hsin-I Lee; Pei-Yi Su; Wen-Hsuan Wu; Po-Huang Lee; Lih-Hwa Hwang; Ding-Shinn Chen
Combining antiangiogenic therapy with immunotherapy exerts better therapeutical effects on large tumors in a woodchuck hepatoma model.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(33):14769-74.
2010: Shiou-Hwei Yeh; Pei-Jer Chen
Gender disparity of hepatocellular carcinoma: the roles of sex hormones.
Oncology 2010;78 Suppl 1():172-9.
2010: Ming-Lung Yu; Chuan-Mo Lee; Wan-Long Chuang; Sheng-Nan Lu; Chia-Yen Dai; Jee-Fu Huang; Zu-Yau Lin; Tsung-Hui Hu; Chien-Hung Chen; Chao-Hung Hung; Jin-Houng Wang; Chi-Ling Chen; Jia-Horng Kao; Ming-Yang Lai; Chen-Hua Liu; Tung-Hung Su; Shun-Sheng Wu; Li-Ying Liao; Hsing-Tao Kuo; You-Chen Chao; Shui-Yi Tung; Sien-Sing Yang; Pei-Jer Chen; Chun-Jen Liu; Ding-Shinn Chen
HBsAg profiles in patients receiving peginterferon alfa-2a plus ribavirin for the treatment of dual chronic infection with hepatitis B and C viruses.
The Journal of infectious diseases 2010;202(1):86-92.
2010: Chih-Hung Hsu; Ying-Chun Shen; Zhong-Zhe Lin; Pei-Jer Chen; Yu-Yun Shao; Yea-Hui Ding; Chiun Hsu; Ann-Lii Cheng
Phase II study of combining sorafenib with metronomic tegafur/uracil for advanced hepatocellular carcinoma.
Journal of hepatology 2010;53(1):126-31.
2010: Chen-Hua Liu; Cheng-Chao Liang; Chun-Jen Liu; Shih-Jer Hsu; Jou-Wei Lin; Shih-I Chen; Peir-Haur Hung; Hung-Bin Tsai; Ming-Yang Lai; Pei-Jer Chen; Jun-Herng Chen; Ding-Shinn Chen; Jia-Horng Kao
The ratio of aminotransferase to platelets is a useful index for predicting hepatic fibrosis in hemodialysis patients with chronic hepatitis C.
Kidney international 2010;78(1):103-9.
2010: Yi-Jiun Lin; Li-Rung Huang; Hung-Chih Yang; Horng-Tay Tzeng; Ping-Ning Hsu; Hui-Lin Wu; Pei-Jer Chen; Ding-Shinn Chen
Hepatitis B virus core antigen determines viral persistence in a C57BL/6 mouse model.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(20):9340-5.
2010: Hwai-I Yang; Morris Sherman; Jun Su; Pei-Jer Chen; Yun-Fan Liaw; Uchenna H Iloeje; Chien-Jen Chen
Nomograms for risk of hepatocellular carcinoma in patients with chronic hepatitis B virus infection.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(14):2437-44.
2010: Ching-Sheng Hsu; Chen-Hua Liu; Chun-Jen Liu; Shih-Jer Hsu; Chi-Ling Chen; Juey-Jen Hwang; Ming-Yang Lai; Pei-Jer Chen; Ding-Shinn Chen; Jia-Horng Kao
Association of metabolic profiles with hepatic fibrosis in chronic hepatitis C patients with genotype 1 or 2 infection.
Journal of gastroenterology and hepatology 2010;25(5):970-7.
2010: Hong-Yuan Hsu; Mei-Hwei Chang; Yen-Hsuan Ni; Cheng-Lun Chiang; Huey-Ling Chen; Wu Jia-Feng; Pei-Jer Chen
No increase in prevalence of hepatitis B surface antigen mutant in a population of children and adolescents who were fully covered by universal infant immunization.
The Journal of infectious diseases 2010;201(8):1192-200.
2010: Hurng-Yi Wang; Ming-Hung Chien; Hsiang-Po Huang; Hsiao-Chi Chang; Chung-Che Wu; Pei-Jer Chen; Mei-Hwei Chang; Ding-Shinn Chen
Distinct hepatitis B virus dynamics in the immunotolerant and early immunoclearance phases.
Journal of virology 2010;84(7):3454-63.
2010: Dasheng Lee; Pei-Jer Chen; Gwo-Bin Lee
The evolution of real-time PCR machines to real-time PCR chips.
Biosensors & bioelectronics 2010;25(7):1820-4.
2010: Shiao-Ya Hong; Pei-Jer Chen
Phosphorylation of serine 177 of the small hepatitis delta antigen regulates viral antigenomic RNA replication by interacting with the processive RNA polymerase II.
Journal of virology 2010;84(3):1430-8.
2010: Tung-Hung Su; Ching-Sheng Hsu; Chi-Ling Chen; Chen-Hua Liu; Yi-Wen Huang; Tai-Chung Tseng; Chun-Jen Liu; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen; Jia-Horng Kao
Serum hepatitis B surface antigen concentration correlates with HBV DNA level in patients with chronic hepatitis B.
Antiviral therapy 2010;15(8):1133-9.
2010: Ching-Sheng Hsu; Chia-Chi Wang; Pin-Chao Wang; Hans Hsienhong Lin; Tai-Chung Tseng; Chien-Hwa Chen; Wei-Chih Su; Chun-Jen Liu; Chi-Ling Chen; Ming-Yang Lai; Pei-Jer Chen; Ding-Shinn Chen; Jia-Horng Kao
Increased incidence of gastroesophageal reflux disease in patients with chronic hepatitis B virus infection.
Hepatology international 2010;4(3):585-93.
2010: Winnie Yeo; Pei-Jer Chen; Junji Furuse; Kwang-Hyub Han; Chiun Hsu; Ho-Yeong Lim; Hanlim Moon; Shukui Qin; Ee-Min Yeoh; Sheng-Long Ye
Eastern Asian expert panel opinion: designing clinical trials of molecular targeted therapy for hepatocellular carcinoma.
BMC cancer 2010;10():620.
2010: Jia-Horng Kao; Pei-Jer Chen; Ding-Shinn Chen
Recent advances in the research of hepatitis B virus-related hepatocellular carcinoma: epidemiologic and molecular biological aspects.
Advances in cancer research 2010;108():21-72.
2010: Masao Omata; Laurentius A Lesmana; Ryosuke Tateishi; Pei-Jer Chen; Shi-Ming Lin; Haruhiko Yoshida; Masatoshi Kudo; Jeong Min Lee; Byung Ihn Choi; Ronnie T P Poon; Shuichiro Shiina; Ann-Lii Cheng; Ji-Dong Jia; Shuntaro Obi; Kwang-Hyub Han; Wasim Jafri; Pierce Chow; Seng Gee Lim; Yogesh K Chawla; Unggul Budihusodo; Rino A Gani; C Rinaldi Lesmana; Terawan Agus Putranto; Yun-Fan Liaw; Shiv Kumar Sarin
Asian Pacific Association for the Study of the Liver consensus recommendations on hepatocellular carcinoma.
Hepatology international 2010;4(2):439-74.
2010: Sang Hoon Ahn; Henry L Y Chan; Pei-Jer Chen; Jun Cheng; Mahesh K Goenka; Jinlin Hou; Seng Gee Lim; Masao Omata; Teerha Piratvisuth; Qing Xie; Hyung Joon Yim; Man-Fung Yuen
Chronic hepatitis B: whom to treat and for how long? Propositions, challenges, and future directions.
Hepatology international 2010;4(1):386-95.
2010: Yu-Hsun Chiu; Chen-Chi Wu; Ying-Chang Lu; Pei-Jer Chen; Wen-Yuan Lee; Alyssa Yan-Zhen Liu; Chuan-Jen Hsu
Mutations in the OTOF gene in Taiwanese patients with auditory neuropathy.
Audiology & neuro-otology 2010;15(6):364-74.
2010: Hai Yu; Quan Yuan; Sheng-Xiang Ge; Hurng-Yi Wang; Ya-Li Zhang; Qing-Rui Chen; Jun Zhang; Pei-Jer Chen; Ning-Shao Xia
Molecular and phylogenetic analyses suggest an additional hepatitis B virus genotype "I".
PloS one 2010;5(2):e9297.
2010: Kuen-Feng Chen; Hui-Chuan Yu; Tsung-Hao Liu; Shoei-Sheng Lee; Pei-Jer Chen; Ann-Lii Cheng
Synergistic interactions between sorafenib and bortezomib in hepatocellular carcinoma involve PP2A-dependent Akt inactivation.
Journal of hepatology 2010;52(1):88-95.
2010: Y-W Huang; Y-T Liao; W Chen; C-L Chen; J-T Hu; C-J Liu; M-Y Lai; Pei-Jer Chen; Ding-Shinn Chen; S-S Yang; J-H Kao
Vitamin D receptor gene polymorphisms and distinct clinical phenotypes of hepatitis B carriers in Taiwan.
Genes and immunity 2010;11(1):87-93.
2010: Chen-Chi Wu; Ying-Chang Lu; Pei-Jer Chen; Po-Lin Yeh; Yi-Nin Su; Wuh-Liang Hwu; Chuan-Jen Hsu
Phenotypic analyses and mutation screening of the SLC26A4 and FOXI1 genes in 101 Taiwanese families with bilateral nonsyndromic enlarged vestibular aqueduct (DFNB4) or Pendred syndrome.
Audiology & neuro-otology 2010;15(1):57-66.
2009: Chen-Chi Wu; Ying-Chang Lu; Pei-Jer Chen; Alyssa Yan-Zhen Liu; Wuh-Liang Hwu; Chuan-Jen Hsu
Application of SNaPshot multiplex assays for simultaneous multigene mutation screening in patients with idiopathic sensorineural hearing impairment.
The Laryngoscope 2009;119(12):2411-6.
2009: Chun-Jen Liu; Pei-Jer Chen; Ding-Shinn Chen
Dual chronic hepatitis B virus and hepatitis C virus infection.
Hepatology international 2009;3(4):517-25.
2009: Chia Hung Chou; Pei-Jer Chen; Yung-Ming Jeng; Ann-Lii Cheng; Li-Rung Huang; Jason Chia-Hsien Cheng
Synergistic effect of radiation and interleukin-6 on hepatitis B virus reactivation in liver through STAT3 signaling pathway.
International journal of radiation oncology, biology, physics 2009;75(5):1545-52.
2009: Fang-Tzy Wu; S Y Liang; K C Tsao; C G Huang; C Y Lin; J S Lin; C Y Su; H L Eng; Jyh-Yuan Yang; Pei-Jer Chen; C F Yang
Hospital-based surveillance and molecular epidemiology of rotavirus infection in Taiwan, 2005-2007.
Vaccine 2009;27 Suppl 5():F50-4.
2009: Sheng-Han Wang; Shiou-Hwei Yeh; Wei-Hsiang Lin; Hurng-Yi Wang; Ding-Shinn Chen; Pei-Jer Chen
Identification of androgen response elements in the enhancer I of hepatitis B virus: a mechanism for sex disparity in chronic hepatitis B.
Hepatology (Baltimore, Md.) 2009;50(5):1392-402.
2009: S-T Chen; Y-H Ni; Pei-Jer Chen; H-L Chen; Y-M Jeng; M-Y Lu; Wu Jia-Feng; H-Y Hsu; M-H Chang
Low viraemia at enrollment in children with chronic hepatitis C favours spontaneous viral clearance.
Journal of viral hepatitis 2009;16(11):796-801.
2009: Wei-Liang Shih; Ming-Whei Yu; Pei-Jer Chen; Tzyy-choou Wu; Chih-Lin Lin; Chun-Jen Liu; Shi-Ming Lin; Dar-In Tai; Shou-Dong Lee; Yun-Fan Liaw
Evidence for association with hepatocellular carcinoma at the PAPSS1 locus on chromosome 4q25 in a family-based study.
European journal of human genetics : EJHG 2009;17(10):1250-9.
2009: Chiun Hsu; Shu-Chen Wei; Ann-Lii Cheng; Pei-Jer Chen
Strategies to prevent hepatitis B virus reactivation in patients receiving immunosuppressive therapy.
Hepatology (Baltimore, Md.) 2009;50(2):654-5.
2009: Chiun Hsu; Ann-Lii Cheng; Pei-Jer Chen
Lamivudine and hepatitis B reactivation.
Annals of internal medicine 2009;151(2):141; author reply 141-2.
2009: Ju-Fang Chang; Pei-Jer Chen; Daniel Y Sze; Tony Reid; David Bartlett; David H Kirn; Ta-Chiang Liu
Oncolytic virotherapy for advanced liver tumours.
Journal of cellular and molecular medicine 2009;13(7):1238-47.
2009: Chun-Jen Liu; Pei-Jer Chen; Ming-Yang Lai; Chen-Hua Liu; Chi-Lin Chen; Jia-Horng Kao; Ding-Shinn Chen
High serum adiponectin correlates with advanced liver disease in patients with chronic hepatitis B virus infection.
Hepatology international 2009;3(2):364-70.
2009: Chien-Shu Chen; Chun-Tang Chiou; Grace Shiahuy Chen; Sheng-Chia Chen; Chih-Yung Hu; Wei-Kuang Chi; YD Chu; Lih-Hwa Hwang; Pei-Jer Chen; Ding-Shinn Chen; Shwu-Huey Liaw; Ji-Wang Chern
Structure-based discovery of triphenylmethane derivatives as inhibitors of hepatitis C virus helicase.
Journal of medicinal chemistry 2009;52(9):2716-23.
2009: Chun-Jen Liu; Po-Huang Lee; Deng-Yn Lin; Cheng-Chung Wu; Long-Bin Jeng; Pin-Wen Lin; King-Tong Mok; Wei-Chen Lee; Hong-Zen Yeh; Ming-Chih Ho; Sheng-Shun Yang; Ching-Chih Lee; Ming-Chin Yu; Rey-Heng Hu; Cheng-Yuan Peng; Kuan-Lang Lai; Stanley Shi-Chung Chang; Pei-Jer Chen
Heparanase inhibitor PI-88 as adjuvant therapy for hepatocellular carcinoma after curative resection: a randomized phase II trial for safety and optimal dosage.
Journal of hepatology 2009;50(5):958-68.
2009: Wan-Jen Yang; Ching-Ju Chang; Shiou-Hwei Yeh; Wei-Hsiang Lin; Sheng-Han Wang; Ting-Fen Tsai; Ding-Shinn Chen; Pei-Jer Chen
Hepatitis B virus X protein enhances the transcriptional activity of the androgen receptor through c-Src and glycogen synthase kinase-3beta kinase pathways.
Hepatology (Baltimore, Md.) 2009;49(5):1515-24.
2009: Kuen-Feng Chen; Pei-Yen Yeh; Chiun Hsu; Chih-Hung Hsu; Yen-Shen Lu; Hsing-Pang Hsieh; Pei-Jer Chen; Ann-Lii Cheng
Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway.
The Journal of biological chemistry 2009;284(17):11121-33.
2009: Yi-Wen Huang; Chung-Yi Hu; Chi-Lin Chen; Ya-Tang Liao; Chun-Jen Liu; Ming-Yang Lai; Pei-Jer Chen; Sien-Sing Yang; Jui-Ting Hu; Ding-Shinn Chen; Jia-Horng Kao
Human leukocyte antigen-DRB1*1101 correlates with less severe hepatitis in Taiwanese male carriers of hepatitis B virus.
Journal of medical virology 2009;81(4):588-93.
2009: Liang-Ju Chien; Jung-Hao Wang; Tsung-Min Hsieh; Ping-Hei Chen; Pei-Jer Chen; Da-Sheng Lee; Ching-Hsing Luo; Gwo-Bin Lee
A micro circulating PCR chip using a suction-type membrane for fluidic transport.
Biomedical microdevices 2009;11(2):359-67.
2009: LH Tseng; Barry Storer; Effie W Petersdorf; Ming-Tseh Lin; Jason W Chien; Bryan M Grogan; Mari Malkki; Pei-Jer Chen; Lue Ping Zhao; Paul J Martin; John A Hansen
IL10 and IL10 receptor gene variation and outcomes after unrelated and related hematopoietic cell transplantation.
Transplantation 2009;87(5):704-10.
2009: Ching-Sheng Hsu; Chen-Hua Liu; Chun-Jen Liu; Chia-Chi Wang; Chi-Ling Chen; Ming-Yang Lai; Pei-Jer Chen; Ding-Shinn Chen; Jia-Horng Kao
Association of lipid profiles with hepatitis C viral load in chronic hepatitis C patients with genotype 1 or 2 infection.
The American journal of gastroenterology 2009;104(3):598-604.
2009: Wen-Chan Huang; Li-Min Huang; I-Shou Chang; Luan-Yin Chang; Bor-Luen Chiang; Pei-Jer Chen; Mei-Hwan Wu; Hung-Chi Lue; Chun-Yun Lee
Epidemiologic features of Kawasaki disease in Taiwan, 2003-2006.
Pediatrics 2009;123(3):e401-5.
2009: Chun-Jen Liu; Yung-Ming Jeng; Chi-Lin Chen; Huei-Ru Cheng; Pei-Jer Chen; Ting-Chi Chen; Chen-Hua Liu; Ming-Yang Lai; Ding-Shinn Chen; Jia-Horng Kao
Hepatitis B virus basal core promoter mutation and DNA load correlate with expression of hepatitis B core antigen in patients with chronic hepatitis B.
The Journal of infectious diseases 2009;199(5):742-9.
2009: Chia-Hsin Wu; Shiou-Hwei Yeh; Yeou-Guang Tsay; Ya-Hsiung Shieh; Chuan-Liang Kao; Yen-Shun Chen; Sheng-Han Wang; Ti-Jung Kuo; Ding-Shinn Chen; Pei-Jer Chen
Glycogen synthase kinase-3 regulates the phosphorylation of severe acute respiratory syndrome coronavirus nucleocapsid protein and viral replication.
The Journal of biological chemistry 2009;284(8):5229-39.
2009: Chun-Jen Liu; Wan-Long Chuang; Chuan-Mo Lee; Ming-Lung Yu; Sheng-Nan Lu; Shun-Sheng Wu; Li-Ying Liao; Chi-Ling Chen; Hsing-Tao Kuo; You-Chen Chao; Shui-Yi Tung; Sien-Sing Yang; Jia-Horng Kao; Chen-Hua Liu; Wei-Wen Su; Chih-Lin Lin; Yung-Ming Jeng; Pei-Jer Chen; Ding-Shinn Chen
Peginterferon alfa-2a plus ribavirin for the treatment of dual chronic infection with hepatitis B and C viruses.
Gastroenterology 2009;136(2):496-504.e3.
2009: Wan-Hsin Liu; Shiou-Hwei Yeh; Cho-Chun Lu; Sung-Liang Yu; Hsuan-Yu Chen; Chien-Yu Lin; Ding-Shinn Chen; Pei-Jer Chen
MicroRNA-18a prevents estrogen receptor-alpha expression, promoting proliferation of hepatocellular carcinoma cells.
Gastroenterology 2009;136(2):683-93.
2009: Ting-Hui Hsieh; Tai-Chung Tseng; Chun-Jen Liu; Ming-Yang Lai; Pei-Jer Chen; Hsin-Ling Hsieh; Ding-Shinn Chen; Jia-Horng Kao
Hepatitis B virus genotype B has an earlier emergence of lamivudine resistance than genotype C.
Antiviral therapy 2009;14(8):1157-63.
2009: Tai-Chung Tseng; Chun-Jen Liu; Chia-Chi Wang; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen; Jia-Horng Kao
Association of baseline viral factors with response to lamivudine therapy in chronic hepatitis B patients with high serum alanine aminotransferase levels.
Antiviral therapy 2009;14(2):203-10.
2009: Ching-Sheng Hsu; Chen-Hua Liu; Chun-Jen Liu; Chi-Ling Chen; Ming-Yang Lai; Pei-Jer Chen; Ding-Shinn Chen; Jia-Horng Kao
Factors affecting early viral load decline of Asian chronic hepatitis C patients receiving pegylated interferon plus ribavirin therapy.
Antiviral therapy 2009;14(1):45-54.
2009: Chun-Jen Liu; Y-J Huang; Hui-Ling Chen; H-T Lin; H-L Lin; Min-Liang Kuo; J-L Huang; Ding-Shinn Chen; Pei-Jer Chen; Hua-Lin Wu
Characterization of interleukin 8 in woodchucks with chronic hepatitis B and hepatocellular carcinoma.
Genes and immunity 2009;10(1):27-36.
2008: Ya-Hui Tsai; Wan-Fen Kuang; Tsai-Yi Lu; Jia-Horng Kao; Ming-Yang Lai; Chun-Jen Liu; Pei-Jer Chen; Lih-Hwa Hwang
The non-structural 5A protein of hepatitis C virus exhibits genotypic differences in interferon antagonism.
Journal of hepatology 2008;49(6):899-907.
2008: Chen-Hua Liu; Chun-Jen Liu; Chih-Lin Lin; Cheng-Chao Liang; Shih-Jer Hsu; Sheng-Shun Yang; Ching-Sheng Hsu; Tai-Chung Tseng; Chia-Chi Wang; Ming-Yang Lai; Jun-Herng Chen; Pei-Jer Chen; Ding-Shinn Chen; Jia-Horng Kao
Pegylated interferon-alpha-2a plus ribavirin for treatment-naive Asian patients with hepatitis C virus genotype 1 infection: a multicenter, randomized controlled trial.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008;47(10):1260-9.
2008: Yuan-Pin Huang; Tsuey-Li Lin; Chuan-Yi Kuo; Miao-Wen Lin; Ching-Yuan Yao; Hui-Wen Liao; Li-Ching Hsu; Chen-Fu Yang; Jyh-Yuan Yang; Pei-Jer Chen; Ho-Sheng Wu
The circulation of subgenogroups B5 and C5 of enterovirus 71 in Taiwan from 2006 to 2007.
Virus research 2008;137(2):206-12.
2008: Hong-Yuan Hsu; Hsiu-Yuan Tsai; Tzee-Chung Wu; Cheng-Lun Chiang; Yen-Hsuan Ni; Pei-Jer Chen; Mei-Hwei Chang
Interferon-alpha treatment in children and young adults with chronic hepatitis B: a long-term follow-up study in Taiwan.
Liver international : official journal of the International Association for the Study of the Liver 2008;28(9):1288-97.
2008: Ping-Huei Tseng; Chun-Jen Liu; Jia-Horng Kao; Chia-Tung Shun; Pei-Jer Chen; Ding-Shinn Chen
Disease progression in a patient with nonalcoholic steatohepatitis.
Journal of the Formosan Medical Association = Taiwan yi zhi 2008;107(10):816-21.
2008: Tung-Hung Su; Chun-Jen Liu; Pei-Jer Chen; Ding-Shinn Chen; Jia-Horng Kao
Acute fatty liver of pregnancy with concurrent acute hepatitis B virus infection.
The American journal of gastroenterology 2008;103(10):2663-5.
2008: Yen-Shun Chen; Wen-Hung Huang; Shiao-Ya Hong; Yeou-Guang Tsay; Pei-Jer Chen
ERK1/2-mediated phosphorylation of small hepatitis delta antigen at serine 177 enhances hepatitis delta virus antigenomic RNA replication.
Journal of virology 2008;82(19):9345-58.
2008: Hwai-I Yang; Shiou-Hwei Yeh; Pei-Jer Chen; Uchenna H Iloeje; Chin-Lan Jen; Jun Su; Li-Yu Wang; Sheng-Nan Lu; San-Lin You; Ding-Shinn Chen; Yun-Fan Liaw; Chien-Jen Chen
Associations between hepatitis B virus genotype and mutants and the risk of hepatocellular carcinoma.
Journal of the National Cancer Institute 2008;100(16):1134-43.
2008: Tai-Chung Tseng; Chun-Jen Liu; Chia-Chi Wang; Pei-Jer Chen; Ming-Yang Lai; Jia-Horng Kao; Ding-Shinn Chen
A higher alanine aminotransferase level correlates with earlier hepatitis B e antigen seroconversion in lamivudine-treated chronic hepatitis B patients.
Liver international : official journal of the International Association for the Study of the Liver 2008;28(7):1034-41.
2008: Ken N Kuo; Tsann-Long Hwang; Pei-Jer Chen
Physician-scientist: attitude of graduates of clinical medicine graduate schools.
Journal of the Formosan Medical Association = Taiwan yi zhi 2008;107(7):519-26.
2008: Chi-Ling Chen; Hwai-I Yang; Wei-Shiung Yang; Chun-Jen Liu; Pei-Jer Chen; San-Lin You; Li-Yu Wang; Chien-An Sun; Sheng-Nan Lu; Ding-Shin Chen; Chien-Jen Chen
Metabolic factors and risk of hepatocellular carcinoma by chronic hepatitis B/C infection: a follow-up study in Taiwan.
Gastroenterology 2008;135(1):111-21.
2008: Chen-Hua Liu; Shih-Jer Hsu; Cheng-Chao Liang; Feng-Chiao Tsai; Jou-Wei Lin; Chun-Jen Liu; Pei-Ming Yang; Ming-Yang Lai; Pei-Jer Chen; Jun-Herng Chen; Jia-Horng Kao; Ding-Shinn Chen
Esophageal varices: noninvasive diagnosis with duplex Doppler US in patients with compensated cirrhosis.
Radiology 2008;248(1):132-9.
2008: Ching-Sheng Hsu; Chun-Jen Liu; Chen-Hua Liu; Chi-Ling Chen; Ming-Yang Lai; Pei-Jer Chen; Ding-Shinn Chen; Jia-Horng Kao
Metabolic profiles in patients with chronic hepatitis C: a case-control study.
Hepatology international 2008;2(2):250-7.
2008: Lei Li; Pei-Jer Chen; Ming-Hung Chen; Kin-Fu Chak; Kuo-Sin Lin; Su-Jen Lin Tsai
A pilot study for screening blood donors in Taiwan by nucleic acid amplification technology: detecting occult hepatitis B virus infections and closing the serologic window period for hepatitis C virus.
Transfusion 2008;48(6):1198-206.
2008: Chun-Yi Lu; Yen-Hsuan Ni; Bor-Luen Chiang; Pei-Jer Chen; Mei-Hwei Chang; Luan-Yin Chang; Ih-Jen Su; Hsu-Sung Kuo; Li-Min Huang; Ding-Shinn Chen; Chin-Yun Lee
Humoral and cellular immune responses to a hepatitis B vaccine booster 15-18 years after neonatal immunization.
The Journal of infectious diseases 2008;197(10):1419-26.
2008: Pei-Jer Chen; Y Hwang; Cherry Guan-Ju Lin; Ying-Jye Wu; Lawrence Shih-Hsin Wu
The genetic differences with whole genome linkage disequilibrium mapping between responder and non-responder in interferon-alpha and ribavirin combined therapy for chronic hepatitis C patients.
International journal of immunogenetics 2008;35(2):153-7.
2008: Jhih-Wei Jian; Guang-Wu Chen; Cheng-Tsung Lai; Li-Ching Hsu; Pei-Jer Chen; Steve Hsu-Sung Kuo; Ho-Sheng Wu; Shin-Ru Shih
Genetic and epidemiological analysis of influenza virus epidemics in Taiwan during 2003 to 2006.
Journal of clinical microbiology 2008;46(4):1426-34.
2008: C-H Liu; C-C Liang; Jou-Wei Lin; S-I Chen; Hung-Bin Tsai; C-S Chang; P-H Hung; Jia-Horng Kao; Chun-Jen Liu; Ming-Yang Lai; J-H Chen; Pei-Jer Chen; J-H Kao; Ding-Shinn Chen
Pegylated interferon alpha-2a versus standard interferon alpha-2a for treatment-naive dialysis patients with chronic hepatitis C: a randomised study.
Gut 2008;57(4):525-30.
2008: Yi-Wen Huang; Chih-Lin Lin; Pei-Jer Chen; Ming-Yang Lai; Jia-Horng Kao; Ding-Shinn Chen
Hepatitis B viral genotype in Taiwanese patients with acute hepatitis B.
Hepato-gastroenterology 2008;55(82-83):633-5.
2008: Chen-Chi Wu; Yi-Chin Lee; Pei-Jer Chen; Chuan-Jen Hsu
Predominance of genetic diagnosis and imaging results as predictors in determining the speech perception performance outcome after cochlear implantation in children.
Archives of pediatrics & adolescent medicine 2008;162(3):269-76.
2008: Chiun Hsu; Chao A Hsiung; Ih-Jen Su; Wei-Shou Hwang; Ming-Chung Wang; Sheng-Fung Lin; Tseng-Hsi Lin; Hui-Hua Hsiao; Ji-Hsiung Young; Ming-Chih Chang; Yu-Min Liao; Chi-Cheng Li; Hung-Bo Wu; Hwei-Fang Tien; Tsu-Yi Chao; Tsang-Wu Liu; Ann-Lii Cheng; Pei-Jer Chen
A revisit of prophylactic lamivudine for chemotherapy-associated hepatitis B reactivation in non-Hodgkin's lymphoma: a randomized trial.
Hepatology (Baltimore, Md.) 2008;47(3):844-53.
2008: Alexander Tan; Shiou-Hwie Yeh; Chun-Jen Liu; Claudia Cheung; Pei-Jer Chen
Viral hepatocarcinogenesis: from infection to cancer.
Liver international : official journal of the International Association for the Study of the Liver 2008;28(2):175-88.
2008: Ching-Sheng Hsu; Chun-Jen Liu; Chen-Hua Liu; Chia-Chi Wang; Chi-Ling Chen; Ming-Yang Lai; Pei-Jer Chen; Jia-Horng Kao; Ding-Shinn Chen
High hepatitis C viral load is associated with insulin resistance in patients with chronic hepatitis C.
Liver international : official journal of the International Association for the Study of the Liver 2008;28(2):271-7.
2008: Jhih-Wei Jian; Cheng-Tsung Lai; Chuan-Yi Kuo; Steve Hsu-Sung Kuo; Li-Ching Hsu; Pei-Jer Chen; Ho-Sheng Wu; Ming-Tsan Liu
Genetic analysis and evaluation of the reassortment of influenza B viruses isolated in Taiwan during the 2004-2005 and 2006-2007 epidemics.
Virus research 2008;131(2):243-9.
2008: Yi-Hsien Shih; Shiou-Hwei Yeh; Pei-Jer Chen; Wen-Pin Chou; Hurng-Yi Wang; Chun-Jen Liu; Su-Feng Lu; Ding-Shinn Chen
Hepatitis B virus quantification and detection of YMDD mutants in a single reaction by real-time PCR and annealing curve analysis.
Antiviral therapy 2008;13(4):469-80.
2008: Chen-Chi Wu; Pei-Jer Chen; Yu-Hsun Chiu; Ying-Chang Lu; Ming-Chueh Wu; Chuan-Jen Hsu
Prospective mutation screening of three common deafness genes in a large Taiwanese Cohort with idiopathic bilateral sensorineural hearing impairment reveals a difference in the results between families from hospitals and those from rehabilitation facilities.
Audiology & neuro-otology 2008;13(3):172-81.
2008: Wen-Hung Huang; Yen-Shun Chen; Pei-Jer Chen
Nucleolar targeting of hepatitis delta antigen abolishes its ability to initiate viral antigenomic RNA replication.
Journal of virology 2008;82(2):692-9.
2008: Y-C Chou; Ming-Whei Yu; C-F Wu; Shi-Yi Yang; Chih-Lin Lin; Chun-Jen Liu; Wei-Liang Shih; Pei-Jer Chen; Yun-Fan Liaw; Chien-Jen Chen
Temporal relationship between hepatitis B virus enhancer II/basal core promoter sequence variation and risk of hepatocellular carcinoma.
Gut 2008;57(1):91-7.
2007: Wang-Huei Sheng; Jia-Horng Kao; Pei-Jer Chen; Li-Min Huang; Sui-Yuan Chang; Hsin-Yun Sun; Chien-Ching Hung; Mao-Yuan Chen; Shan-Chwen Chang
Evolution of hepatitis B serological markers in HIV-infected patients receiving highly active antiretroviral therapy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007;45(9):1221-9.
2007: Chih-Lin Lin; Chun-Jen Liu; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen; Jia-Horng Kao
High prevalence of occult hepatitis B virus infection in Taiwanese intravenous drug users.
Journal of medical virology 2007;79(11):1674-8.
2007: Chen-Hua Liu; Shih-Jer Hsu; Jou-Wei Lin; Juey-Jen Hwang; Chun-Jen Liu; Pei-Ming Yang; Ming-Yang Lai; Pei-Jer Chen; Jun-Herng Chen; Jia-Horng Kao; Ding-Shinn Chen
Noninvasive diagnosis of hepatic fibrosis in patients with chronic hepatitis C by splenic Doppler impedance index.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2007;5(10):1199-1206.e1.
2007: Sean D Sullivan; David L Veenstra; Pei-Jer Chen; Ting-Tsung Chang; Wan-Long Chuang; Chiaming Tsai; Kavita Patel
Cost-effectiveness of peginterferon alpha-2a compared to lamivudine treatment in patients with hepatitis B e antigen positive chronic hepatitis B in Taiwan.
Journal of gastroenterology and hepatology 2007;22(9):1494-9.
2007: Tai-Chung Tseng; Chun-Jen Liu; Pei-Jer Chen; Ming-Yang Lai; Chih-Lin Lin; Jia-Horng Kao; Ding-Shinn Chen
Subgenotypes of hepatitis B virus genotype C do not correlate with disease progression of chronic hepatitis B in Taiwan.
Liver international : official journal of the International Association for the Study of the Liver 2007;27(7):983-8.
2007: Chih-Lin Lin; Chen-Hua Liu; Wendy Chen; Wen-Ling Huang; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen; Jia-Horng Kao
Association of pre-S deletion mutant of hepatitis B virus with risk of hepatocellular carcinoma.
Journal of gastroenterology and hepatology 2007;22(7):1098-103.
2007: Yen-Hsuan Ni; Mei-Hwei Chang; Pei-Jer Chen; Keh-Sung Tsai; Hong-Yuan Hsu; Huey-Ling Chen; Daw-Jen Tsuei; Ding-Shinn Chen
Viremia profiles in children with chronic hepatitis B virus infection and spontaneous e antigen seroconversion.
Gastroenterology 2007;132(7):2340-5.
2007: Deepak Amarapurkar; Estsuko Hashimoto; Laurentius A Lesmana; Jose Sollano; Pei-Jer Chen; Khean-Lee Goh
How common is non-alcoholic fatty liver disease in the Asia-Pacific region and are there local differences?
Journal of gastroenterology and hepatology 2007;22(6):788-93.
2007: Chen-Chi Wu; Yu-Hsun Chiu; Pei-Jer Chen; Chuan-Jen Hsu
Prevalence and clinical features of the mitochondrial m.1555A>G mutation in Taiwanese patients with idiopathic sensorineural hearing loss and association of haplogroup F with low penetrance in three families.
Ear and hearing 2007;28(3):332-42.
2007: Chih-Lin Lin; Li-Ying Liao; Chun-Jen Liu; Ming-Whei Yu; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen; Jia-Horng Kao
Hepatitis B viral factors in HBeAg-negative carriers with persistently normal serum alanine aminotransferase levels.
Hepatology (Baltimore, Md.) 2007;45(5):1193-8.
2007: Masaji Okada; Yoshinobu Okuno; Satomi Hashimoto; Yoko Kita; Noriko Kanamaru; Yasuko Nishida; Yoshie Tsunai; Ruriko Inoue; Hitoshi Nakatani; Reiko Fukamizu; Yumi Namie; Junko Yamada; Kyoko Takao; Ritsuko Asai; Ryoko Asaki; Tetsuo Kase; Yuji Takemoto; Shigeto Yoshida; J S M Peiris; Pei-Jer Chen; Naoki Yamamoto; Tatsuji Nomura; Isao Ishida; Shigeru Morikawa; Masato Tashiro; Mitsunori Sakatani
Development of vaccines and passive immunotherapy against SARS corona virus using SCID-PBL/hu mouse models.
Vaccine 2007;25(16):3038-40.
2007: Shiou-Hwei Yeh; Chi-Ming Chiu; Chi-Ling Chen; Shu-Fen Lu; Hey-Chi Hsu; Ding-Shinn Chen; Pei-Jer Chen
Somatic mutations at the trinucleotide repeats of androgen receptor gene in male hepatocellular carcinoma.
International journal of cancer. Journal international du cancer 2007;120(8):1610-7.
2007: Wang-Huei Sheng; Chien-Ching Hung; Jia-Horng Kao; Sui-Yuan Chang; Mao-Yuan Chen; Szu-Min Hsieh; Pei-Jer Chen; Shan-Chwen Chang
Impact of hepatitis D virus infection on the long-term outcomes of patients with hepatitis B virus and HIV coinfection in the era of highly active antiretroviral therapy: a matched cohort study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007;44(7):988-95.
2007: Chi-Ming Chiu; Shiou-Hwei Yeh; Pei-Jer Chen; Ti-Jung Kuo; Ching-Ju Chang; Po-Jen Chen; Wan-Jen Yang; Ding-Shinn Chen
Hepatitis B virus X protein enhances androgen receptor-responsive gene expression depending on androgen level.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(8):2571-8.
2007: Wang-Huei Sheng; Chien-Ching Hung; Ruei-Jiuan Wu; Jann-Tay Wang; Pei-Jer Chen; Shan-Chwen Chang; Jia-Horng Kao
Clinical impact of GB virus C viremia on patients with HIV type 1 infection in the era of highly active antiretroviral therapy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007;44(4):584-90.
2007: Chia Hung Chou; Pei-Jer Chen; Po-Huang Lee; Ann-Lii Cheng; Hui-Chen Hsu; Jason Chia-Hsien Cheng
Radiation-induced hepatitis B virus reactivation in liver mediated by the bystander effect from irradiated endothelial cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(3):851-7.
2007: Kao-Lang Liu; Ming-Chih Ho; Pei-Jer Chen
Ectopic liver with hepatocellular carcinoma in the peritoneum.
AJR. American journal of roentgenology 2007;188(2):W206-7.
2007: Ching-Sheng Hsu; Chun-Jen Liu; Ming-Yang Lai; Pei-Jer Chen; Jia-Horng Kao; Ding-Shinn Chen
Early viral kinetics during treatment of chronic hepatitis C virus infection with pegylated interferon alpha plus ribavirin in Taiwan.
Intervirology 2007;50(4):310-5.
2007: C-L Lin; J-D Chen; C-J Liu; P-H Lee; Pei-Jer Chen; M-Y Lai; Jia-Horng Kao; Ding-Shinn Chen
Clinicopathological differences between hepatitis B viral genotype B- and C-related resectable hepatocellular carcinoma.
Journal of viral hepatitis 2007;14(1):64-9.
2007: Wen-Hui Su; Chuan-Chuan Chao; Shiou-Hwei Yeh; Ding-Shinn Chen; Pei-Jer Chen; Yuh-Shan Jou
OncoDB.HCC: an integrated oncogenomic database of hepatocellular carcinoma revealed aberrant cancer target genes and loci.
Nucleic acids research 2007;35(Database issue):D727-31.
2006: Pei-Jer Chen
Genetic mutation in hepatic adenoma: seeing is believing.
Journal of hepatology 2006;45(6):767-9.
2006: Li-Rung Huang; Hui-Lin Wu; Pei-Jer Chen; Ding-Shinn Chen
An immunocompetent mouse model for the tolerance of human chronic hepatitis B virus infection.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(47):17862-7.
2006: Ting-Hui Hsieh; Chun-Jen Liu; Ding-Shinn Chen; Pei-Jer Chen
Natural course and treatment of hepatitis D virus infection.
Journal of the Formosan Medical Association = Taiwan yi zhi 2006;105(11):869-81.
2006: Her-Shyong Shiah; Yee Chao; Li-Tzong Chen; Tzy-Jyun Yao; Jin-Ding Huang; Jang-Yang Chang; Pei-Jer Chen; Tsai-Rong Chuang; Yung-Hsin Chin; Jacqueline Whang-Peng; Tsang-Wu Liu
Phase I and pharmacokinetic study of oral thalidomide in patients with advanced hepatocellular carcinoma.
Cancer chemotherapy and pharmacology 2006;58(5):654-64.
2006: Chun-Jen Liu; Pei-Jer Chen; Ming-Yang Lai; Feng-Yi Lin; Tzusan Wang; Jia-Horng Kao; Ding-Shinn Chen
Viral factors correlate with hepatitis B e antigen seroconverson in patients with chronic hepatitis B.
Liver international : official journal of the International Association for the Study of the Liver 2006;26(8):949-55.
2006: Chien-Hung Chen; Guan-Tarn Huang; Pei-Ming Yang; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen; Jung-Der Wang; Jin-Chuan Sheu
Hepatitis B- and C-related hepatocellular carcinomas yield different clinical features and prognosis.
European journal of cancer (Oxford, England : 1990) 2006;42(15):2524-9.
2006: Chun-Jen Liu; Bing-Fang Chen; Pei-Jer Chen; Ming-Yang Lai; Wen-Ling Huang; Jia-Horng Kao; Ding-Shinn Chen
Role of hepatitis B virus precore/core promoter mutations and serum viral load on noncirrhotic hepatocellular carcinoma: a case-control study.
The Journal of infectious diseases 2006;194(5):594-9.
2006: Yuchi Hwang; Ellson Y Chen; Z John Gu; Wan-Long Chuang; Ming-Lung Yu; Ming-Yang Lai; You-Chen Chao; Chuan-Mo Lee; Jing-Houng Wang; Chia-Yen Dai; Monica Shian-Jy Bey; Ya-Tang Liao; Pei-Jer Chen; Ding-Shinn Chen
Genetic predisposition of responsiveness to therapy for chronic hepatitis C.
Pharmacogenomics 2006;7(5):697-709.
2006: Chun-Jen Liu; Jia-Horng Kao; Pei-Jer Chen; T-C Chen; F-Y Lin; Ming-Yang Lai; Ding-Shinn Chen
Overlap lamivudine treatment in patients with chronic hepatitis B receiving adefovir for lamivudine-resistant viral mutants.
Journal of viral hepatitis 2006;13(6):387-95.
2006: Wei-Liang Shih; Ming-Whei Yu; Pei-Jer Chen; Shiou-Hwei Yeh; Men-Tzung Lo; H-C Chang; Yun-Fan Liaw; Shi-Ming Lin; Chun-Jen Liu; Shou-Dong Lee; Chih-Lin Lin; Chuhsing Kate Hsiao; Shi-Yi Yang; Chien-Jen Chen
Localization of a susceptibility locus for hepatocellular carcinoma to chromosome 4q in a hepatitis B hyperendemic area.
Oncogene 2006;25(22):3219-24.
2006: Chun-Jen Liu; Ding-Shinn Chen; Pei-Jer Chen
Epidemiology of HBV infection in Asian blood donors: emphasis on occult HBV infection and the role of NAT.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2006;36 Suppl 1():S33-44.
2006: Yi-Wen Huang; Chih-Lin Lin; Pei-Jer Chen; Ming-Yang Lai; Jia-Horng Kao; Ding-Shinn Chen
Higher cut-off index value of immunoglobulin M antibody to hepatitis B core antigen in Taiwanese patients with hepatitis B.
Journal of gastroenterology and hepatology 2006;21(5):859-62.
2006: Chun-Jen Liu; Bing-Fang Chen; Pei-Jer Chen; Ming-Yang Lai; Wen-Ling Huang; Jia-Horng Kao; Ding-Shinn Chen
Role of hepatitis B viral load and basal core promoter mutation in hepatocellular carcinoma in hepatitis B carriers.
The Journal of infectious diseases 2006;193(9):1258-65.
2006: Bing-Fang Chen; Chun-Jen Liu; Guey-Mei Jow; Pei-Jer Chen; Jia-Horng Kao; Ding-Shinn Chen
High prevalence and mapping of pre-S deletion in hepatitis B virus carriers with progressive liver diseases.
Gastroenterology 2006;130(4):1153-68.
2006: Chun-Jen Liu; Ming-Yang Lai; You-Chen Chao; Li-Ying Liao; Sien-Sing Yang; Tun-Jen Hsiao; Tsai-Yuan Hsieh; Chih-Lin Lin; Jui-Ting Hu; Chi-Ling Chen; Pei-Jer Chen; Jia-Horng Kao; Ding-Shinn Chen
Interferon alpha-2b with and without ribavirin in the treatment of hepatitis B e antigen-positive chronic hepatitis B: a randomized study.
Hepatology (Baltimore, Md.) 2006;43(4):742-9.
2006: Shiou-Hwei Yeh; Dai-Chen Wu; Ching-Yi Tsai; Ti-Jung Kuo; Wei-Che Yu; Yuan-Shau Chang; Chi-Ling Chen; Ching-Fang Chang; Ding-Shinn Chen; Pei-Jer Chen
Genetic characterization of fas-associated phosphatase-1 as a putative tumor suppressor gene on chromosome 4q21.3 in hepatocellular carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(4):1097-108.
2006: LH Tseng; Ming-Tseh Lin; Wen-Yi Shau; W-C Lin; F-Y Chang; K-L Chien; John A Hansen; D-S Chen; Pei-Jer Chen
Correlation of interleukin-10 gene haplotype with hepatocellular carcinoma in Taiwan.
Tissue antigens 2006;67(2):127-33.
2006: Luan-Yin Chang; Bor-Luen Chiang; Chuan-Liang Kao; Mei-Hwan Wu; Pei-Jer Chen; Ben Berkhout; Hui-Ching Yang; Li-Min Huang
Lack of association between infection with a novel human coronavirus (HCoV), HCoV-NH, and Kawasaki disease in Taiwan.
The Journal of infectious diseases 2006;193(2):283-6.
2006: Masaji Okada; Yuji Takemoto; Yoshinobu Okuno; Satomi Hashimoto; Yukari Fukunaga; Takao Tanaka; Yoko Kita; Sachiko Kuwayama; Yumiko Muraki; Noriko Kanamaru; Hiroko Takai; Chika Okada; Yayoi Sakaguchi; Izumi Furukawa; Kyoko Yamada; Miwa Izumiya; Shigeto Yoshida; Makoto Matsumoto; Tetsuo Kase; J S M Peiris; Daphne E Demello; Pei-Jer Chen; Naoki Yamamoto; Yoshiyuki Yoshinaka; Tatsuji Nomura; Isao Ishida; Shigeru Morikawa; Masato Tashiro; Mitsunori Sakatani
Development of vaccines and passive immunotherapy against SARS coronavirus using mouse and SCID-PBL/hu mouse models.
Advances in experimental medicine and biology 2006;581():561-6.
2006: Pei-Jer Chen; Cherry Guan-Ju Lin; Felicia Yi-Fang Lin; Ellson Chen; Lawrence Shih-Hsin Wu
Genetic structural differences between responders and non-responders to interferon therapy for chronic hepatitis-B patients.
Journal of human genetics 2006;51(11):984-91.
2006: Wen-Hung Huang; C W Chen; Hui-Lin Wu; Pei-Jer Chen
Post-translational modification of delta antigen of hepatitis D virus.
Current topics in microbiology and immunology 2006;307():91-112.
2006: Bing-Fang Chen; Chun-Jen Liu; Guey-Mei Jow; Pei-Jer Chen; Jia-Horng Kao; Ding-Shinn Chen
Evolution of Hepatitis B virus in an acute hepatitis B patient co-infected with genotypes B and C.
The Journal of general virology 2006;87(Pt 1):39-49.
2006: Chun-Jen Liu; Shyh-Chyi Lo; Jia-Horng Kao; Ping-Tsung Tseng; Ming-Yang Lai; Yen-Hsuan Ni; Shiou-Hwei Yeh; Pei-Jer Chen; Ding-Shinn Chen
Transmission of occult hepatitis B virus by transfusion to adult and pediatric recipients in Taiwan.
Journal of hepatology 2006;44(1):39-46.
2005: Chih-Lin Lin; Jia-Horng Kao; Bing-Fang Chen; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Application of hepatitis B virus genotyping and phylogenetic analysis in intrafamilial transmission of hepatitis B virus.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005;41(11):1576-81.
2005: Chun-Chieh Chen; Shi-Yi Yang; Chun-Jen Liu; Chih-Lin Lin; Yun-Fan Liaw; Shi-Ming Lin; Shou-Dong Lee; Pei-Jer Chen; Chien-Jen Chen; Ming-Whei Yu
Association of cytokine and DNA repair gene polymorphisms with hepatitis B-related hepatocellular carcinoma.
International journal of epidemiology 2005;34(6):1310-8.
2005: Ming-Tseh Lin; Barry Storer; Paul J Martin; LH Tseng; Bryan Grogan; Pei-Jer Chen; Lue Ping Zhao; John A Hansen
Genetic variation in the IL-10 pathway modulates severity of acute graft-versus-host disease following hematopoietic cell transplantation: synergism between IL-10 genotype of patient and IL-10 receptor beta genotype of donor.
Blood 2005;106(12):3995-4001.
2005: Chun-Jen Liu; Jyh-Ming Liou; Ding-Shinn Chen; Pei-Jer Chen
Natural course and treatment of dual hepatitis B virus and hepatitis C virus infections.
Journal of the Formosan Medical Association = Taiwan yi zhi 2005;104(11):783-91.
2005: Chian-Feng Chen; Shiou-Hwei Yeh; Ding-Shinn Chen; Pei-Jer Chen; Yuh-Shan Jou
Molecular genetic evidence supporting a novel human hepatocellular carcinoma tumor suppressor locus at 13q12.11.
Genes, chromosomes & cancer 2005;44(3):320-8.
2005: Chen-Fu Yang; Hour-Young Chen; Jaume Jorba; Hui-Chih Sun; Su-Ju Yang; Hsiang-Chi Lee; Yhu-Chering Huang; Tzou-Yien Lin; Pei-Jer Chen; Hiroyuki Shimizu; Yorihiro Nishimura; Andi Utama; Mark A Pallansch; Tatsuo Miyamura; Olen M Kew; Jyh-Yuan Yang
Intratypic recombination among lineages of type 1 vaccine-derived poliovirus emerging during chronic infection of an immunodeficient patient.
Journal of virology 2005;79(20):12623-34.
2005: Kuen-Tyng Lin; Shiou-Hwei Yeh; Ding-Shinn Chen; Pei-Jer Chen; Yuh-Shan Jou
Epigenetic activation of alpha4, beta2 and beta6 integrins involved in cell migration in trichostatin A-treated Hep3B cells.
Journal of biomedical science 2005;12(5):803-13.
2005: Wen-Pin Su; Chi-Chung Wen; Chao A Hsiung; Ih-Jen Su; Ann-Lii Cheng; Ming-Chih Chang; Chao-Jung Tsao; Woei-Yau Kao; Wu-Ching Uen; Chiun Hsu; Chih-Hung Hsu; Yen-Shen Lu; Hwei-Fang Tien; Tsu-Yi Chao; Li-Tzong Chen; Jacqueline Whang-Peng; Pei-Jer Chen
Long-term hepatic consequences of chemotherapy-related HBV reactivation in lymphoma patients.
World journal of gastroenterology : WJG 2005;11(34):5283-8.
2005: Yen-Hsuan Ni; Fu-Chen Huang; Tzee-Chung Wu; Man-Shan Kong; Yung-Ming Jeng; Pei-Jer Chen; Daw-Jen Tsuei; Huey-Ling Chen; Hong-Yuan Hsu; Mei-Hwei Chang
Lamivudine treatment in maternally transmitted chronic hepatitis B virus infection patients.
Pediatrics international : official journal of the Japan Pediatric Society 2005;47(4):372-7.
2005: Shih-Jer Hsu; Ping-Huei Tseng; Pei-Jer Chen
Trichuris suis therapy for ulcerative colitis: nonresponsive patients may need anti-helminth therapy.
Gastroenterology 2005;129(2):768-9; author reply 769.
2005: Jin-Ying Lu; Lee-Ming Chuang; Wei-Shiung Yang; Tong-Yuan Tai; Ming-Yang Lai; Pei-Jer Chen; Jia-Horng Kao; Cha-Ze Lee; Hsuan-Shu Lee
Adiponectin levels among patients with chronic hepatitis B and C infections and in response to IFN-alpha therapy.
Liver international : official journal of the International Association for the Study of the Liver 2005;25(4):752-9.
2005: Chun-Jen Liu; Pei-Jer Chen; Yung-Ming Jeng; Wen-Ling Huang; Wei-Shiung Yang; Ming-Yang Lai; Jia-Horng Kao; Ding-Shinn Chen
Serum adiponectin correlates with viral characteristics but not histologic features in patients with chronic hepatitis C.
Journal of hepatology 2005;43(2):235-42.
2005: Guan-Tarn Huang; Po-Huang Lee; Yuk-Ming Tsang; Ming-Yang Lai; Pei-Ming Yang; Rey-Heng Hu; Pei-Jer Chen; Jia-Horng Kao; Jin-Chuan Sheu; Cha-Ze Lee; Ding-Shinn Chen
Percutaneous ethanol injection versus surgical resection for the treatment of small hepatocellular carcinoma: a prospective study.
Annals of surgery 2005;242(1):36-42.
2005: Chen-Chi Wu; Pei-Jer Chen; Chuan-Jen Hsu
Specificity of SLC26A4 mutations in the pathogenesis of inner ear malformations.
Audiology & neuro-otology 2005;10(4):234-42.
2005: Chen-Chi Wu; Te-Huei Yeh; Pei-Jer Chen; Chuan-Jen Hsu
Prevalent SLC26A4 mutations in patients with enlarged vestibular aqueduct and/or Mondini dysplasia: a unique spectrum of mutations in Taiwan, including a frequent founder mutation.
The Laryngoscope 2005;115(6):1060-4.
2005: Chih-Lin Lin; Li-Ying Liao; Chaur-Shine Wang; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen; Jia-Horng Kao
Basal core-promoter mutant of hepatitis B virus and progression of liver disease in hepatitis B e antigen-negative chronic hepatitis B.
Liver international : official journal of the International Association for the Study of the Liver 2005;25(3):564-70.
2005: Ting-Hui Hsieh; Jia-Horng Kao; Ming-Yang Lai; Pei-Jer Chen; Ding-Shinn Chen
Successful treatment with peginterferon and ribavirin in a patient with acute hepatitis C evolving into chronicity.
Journal of the Formosan Medical Association = Taiwan yi zhi 2005;104(5):354-8.
2005: I-Jung Liu; Pei-Jer Chen; Shiou-Hwei Yeh; Yu-Ping Chiang; Li-Min Huang; Ming-Fu Chang; Shey-Ying Chen; Pan-Chyr Yang; Shan-Chwen Chang; Wei-Kung Wang
Immunofluorescence assay for detection of the nucleocapsid antigen of the severe acute respiratory syndrome (SARS)-associated coronavirus in cells derived from throat wash samples of patients with SARS.
Journal of clinical microbiology 2005;43(5):2444-8.
2005: Shin-Ru Shih; Guang-Wu Chen; Ching-Chun Yang; Weng-Zhi Yang; Ding-Ping Liu; Jih-Hui Lin; Shu-Chun Chiu; Haur-Young Chen; Kuo-Chien Tsao; Chung-Guei Huang; Ya-Ling Huang; Chee-Keng Mok; Chi-Jene Chen; Tzou-Yien Lin; Jen-Ren Wang; Chuan-Liang Kao; Kwei-Hsian Lin; Li-Kuang Chen; Hock-Liew Eng; Yung-Ching Liu; Po-Yen Chen; Jen-Shiou Lin; Jen-Hsien Wang; Cheng-Wen Lin; Yu-Jiun Chan; Jang-Jih Lu; Chao A Hsiung; Pei-Jer Chen; Ih-Jen Su
Laboratory-based surveillance and molecular epidemiology of influenza virus in Taiwan.
Journal of clinical microbiology 2005;43(4):1651-61.
2005: Yone-Han Mah; Jia-Horng Kao; Chun-Jen Liu; Chi-Ling Chen; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Prevalence and clinical implications of HFE gene mutations (C282Y and H63D) in patients with chronic hepatitis B and C in Taiwan.
Liver international : official journal of the International Association for the Study of the Liver 2005;25(2):214-9.
2005: Masaji Okada; Yuji Takemoto; Yoshinobu Okuno; Satomi Hashimoto; Shigeto Yoshida; Yukari Fukunaga; Takao Tanaka; Yoko Kita; Sachiko Kuwayama; Yumiko Muraki; Noriko Kanamaru; Hiroko Takai; Chika Okada; Yayoi Sakaguchi; Izumi Furukawa; Kyoko Yamada; Makoto Matsumoto; Tetsuo Kase; Daphne E Demello; J S M Peiris; Pei-Jer Chen; Naoki Yamamoto; Yoshiyuki Yoshinaka; Tatsuji Nomura; Isao Ishida; Shigeru Morikawa; Masato Tashiro; Mitsunori Sakatani
The development of vaccines against SARS corona virus in mice and SCID-PBL/hu mice.
Vaccine 2005;23(17-18):2269-72.
2005: Hui-Lin Wu; Li-Rung Huang; Chuan-Chuan Huang; Hsiao-Lei Lai; Chun-Jen Liu; Yu-Tzu Huang; Yun-Wei Hsu; Cheng-Yi Lu; Ding-Shinn Chen; Pei-Jer Chen
RNA interference-mediated control of hepatitis B virus and emergence of resistant mutant.
Gastroenterology 2005;128(3):708-16.
2005: Ming-Whei Yu; Shiou-Hwei Yeh; Pei-Jer Chen; Yun-Fan Liaw; Chih-Lin Lin; Chun-Jen Liu; Wei-Liang Shih; Jia-Horng Kao; Ding-Shinn Chen; Chien-Jen Chen
Hepatitis B virus genotype and DNA level and hepatocellular carcinoma: a prospective study in men.
Journal of the National Cancer Institute 2005;97(4):265-72.
2005: Chun-Jen Liu; Yung-Ming Jeng; Pei-Jer Chen; Ming-Yang Lai; Hung-Chih Yang; Wen-Ling Huang; Jia-Horng Kao; Ding-Shinn Chen
Influence of metabolic syndrome, viral genotype and antiviral therapy on superimposed fatty liver disease in chronic hepatitis C.
Antiviral therapy 2005;10(3):405-15.
2005: Chen-Chi Wu; Yuh-Shyang Chen; Pei-Jer Chen; Chuan-Jen Hsu
Common clinical features of children with enlarged vestibular aqueduct and Mondini dysplasia.
The Laryngoscope 2005;115(1):132-7.
2004: Chun-Jen Liu; Wen-Ling Huang; Pei-Jer Chen; Ming-Yang Lai; Jia-Horng Kao; Ding-Shinn Chen
End-of-treatment virologic response does not predict relapse after lamivudine treatment for chronic hepatitis B.
World journal of gastroenterology : WJG 2004;10(24):3574-8.
2004: Chun-Jen Liu; Pei-Jer Chen; Ming-Yang Lai; Ting-Chih Chen; Hurng-Yi Wang; Wen-Ling Huang; Jia-Horng Kao; Ding-Shinn Chen
Lack of interferon sensitivity-determining region in the genome of hepatitis B virus genotype Ba.
Antiviral therapy 2004;9(6):895-903.
2004: Po-Ren Hsueh; Li-Min Huang; Pei-Jer Chen; Chuan-Liang Kao; Pan-Chyr Yang
Chronological evolution of IgM, IgA, IgG and neutralisation antibodies after infection with SARS-associated coronavirus.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2004;10(12):1062-6.
2004: Luan-Yin Chang; I-Shou Chang; Chun-Yi Lu; Bor-Luen Chiang; Chin-Yun Lee; Pei-Jer Chen; Jann-Tay Wang; Hong-Nerng Ho; Ding-Shinn Chen; Li-Min Huang
Epidemiologic features of Kawasaki disease in Taiwan, 1996-2002.
Pediatrics 2004;114(6):e678-82.
2004: Bing-Fang Chen; Pei-Jer Chen; Guey-Mei Jow; Erwin Sablon; Chun-Jen Liu; Ding-Shinn Chen; Jia-Horng Kao
High prevalence of mixed genotype infections in hepatitis B virus infected intravenous drug users.
Journal of medical virology 2004;74(4):536-42.
2004: Shiou-Hwei Yeh; Ching-Yi Tsai; Jia-Horng Kao; Chun-Jen Liu; Ti-Jung Kuo; Ming-Wei Lin; Wen-Ling Huang; Shu-Fen Lu; Jane Jih; Ding-Shinn Chen; Pei-Jer Chen
Quantification and genotyping of hepatitis B virus in a single reaction by real-time PCR and melting curve analysis.
Journal of hepatology 2004;41(4):659-66.
2004: Shiou-Hwei Yeh; Ming-Wei Lin; Shu-Fen Lu; Dai-Chen Wu; Shih-Feng Tsai; Ching-Yi Tsai; Ming-Yang Lai; Hey-Chi Hsu; Ding-Shinn Chen; Pei-Jer Chen
Allelic loss of chromosome 4q21 approximately 23 associates with hepatitis B virus-related hepatocarcinogenesis and elevated alpha-fetoprotein.
Hepatology (Baltimore, Md.) 2004;40(4):847-54.
2004: Chun-Jen Liu; Pei-Jer Chen; Ming-Yang Lai; Jia-Horng Kao; Ding-Shinn Chen
Evolution of precore/core promoter mutations in hepatitis B carriers with hepatitis B e antigen seroreversion.
Journal of medical virology 2004;74(2):237-45.
2004: Chia-Jung Hsieh; Tae Woo Kim; Chien-Fu Hung; Jeremy Juang; Michelle Moniz; David A K Boyd; Liangmei He; Pei-Jer Chen; Chien-Hung Chen; Tzyy-choou Wu
Enhancement of vaccinia vaccine potency by linkage of tumor antigen gene to gene encoding calreticulin.
Vaccine 2004;22(29-30):3993-4001.
2004: Cheng-Wen Lin; Chang-Hai Tsai; Fuu-Jen Tsai; Pei-Jer Chen; Chien-Chen Lai; Lei Wan; Hua-Hao Chiu; Kuan-Hsun Lin
Characterization of trans- and cis-cleavage activity of the SARS coronavirus 3CLpro protease: basis for the in vitro screening of anti-SARS drugs.
FEBS letters 2004;574(1-3):131-7.
2004: Chih-Hung Hsu; Hui-Chen Hsu; Hui-Ling Chen; Ming Gao; Pei-Yen Yeh; Pei-Jer Chen; Ann-Lii Cheng
Doxorubicin activates hepatitis B virus (HBV) replication in HBV-harboring hepatoblastoma cells. A possible novel mechanism of HBV reactivation in HBV carriers receiving systemic chemotherapy.
Anticancer research 2004;24(5A):3035-40.
2004: Chun-Jen Liu; Jia-Horng Kao; Hurng-Yi Wang; Ming-Yang Lai; Ting-Chih Chen; Pei-Jer Chen; Ding-Shinn Chen
Origin of serum hepatitis B virus in acute exacerbation: comparison with HBV in the liver and from other exacerbation.
Hepatology (Baltimore, Md.) 2004;40(2):310-17.
2004: Shiou-Hwei Yeh; Jia-Horng Kao; Pei-Jer Chen
Heterogeneity of hereditary persistence of alpha-fetoprotein.
Gastroenterology 2004;127(2):687; author reply 688.
2004: Wei-Kung Wang; Shey-Ying Chen; I-Jung Liu; Yee-Chun Chen; Hui-Ling Chen; Chao-Fu Yang; Pei-Jer Chen; Shiou-Hwei Yeh; Chuan-Liang Kao; Li-Min Huang; Po-Ren Hsueh; Jann-Tay Wang; Wang-Huei Sheng; Chi-Tai Fang; Chien-Ching Hung; Szu-Min Hsieh; Chan-Ping Su; Wen-Chu Chiang; Jyh-Yuan Yang; Jih-Hui Lin; Szu-Chia Hsieh; Hsien-Ping Hu; Yu-Ping Chiang; Jann-Tay Wang; Pan-Chyr Yang; Shan-Chwen Chang
Detection of SARS-associated coronavirus in throat wash and saliva in early diagnosis.
Emerging infectious diseases 2004;10(7):1213-9.
2004: Chun-Jen Liu; Pei-Jer Chen; Ding-Shinn Chen
A forgotten population with chronic hepatitis C infection: subjects coinfected with hepatitis B virus.
Hepatology (Baltimore, Md.) 2004;40(1):266; author reply 267-8.
2004: Li-Rung Huang; Chi-Ming Chiu; Shiou-Hwei Yeh; Wen-Hung Huang; Po-Ren Hsueh; Wen-Zieh Yang; Jyh-Yuan Yang; Ih-Jen Su; Shan-Chwen Chang; Pei-Jer Chen
Evaluation of antibody responses against SARS coronaviral nucleocapsid or spike proteins by immunoblotting or ELISA.
Journal of medical virology 2004;73(3):338-46.
2004: Wei-Tien Chang; Chuan-Liang Kao; Ming-Ya Chung; Shyr-Chyr Chen; Shou-Ju Lin; Wen-Chu Chiang; Shey-Ying Chen; Chan-Ping Su; Po-Ren Hsueh; Wen-Jone Chen; Pei-Jer Chen; Pan-Chyr Yang
SARS exposure and emergency department workers.
Emerging infectious diseases 2004;10(6):1117-9.
2004: Jeong Won Kim; Chien-Fu Hung; Jeremy Juang; Liangmei He; Tae Woo Kim; Deborah K Armstrong; Sara I Pai; Pei-Jer Chen; Cheng-Tao Lin; David A K Boyd; Tzyy-choou Wu
Comparison of HPV DNA vaccines employing intracellular targeting strategies.
Gene therapy 2004;11(12):1011-8.
2004: Yee-Chun Chen; Pei-Jer Chen; Shan-Chwen Chang; Chuan-Liang Kao; Shiou-Hwa Wang; Li-Hua Wang; Pan-Chyr Yang
Infection control and SARS transmission among healthcare workers, Taiwan.
Emerging infectious diseases 2004;10(5):895-8.
2004: Yuh-Shan Jou; Chih-Shia Lee; Ya-Hui Chang; Chin-Fu Hsiao; Chian-Feng Chen; Chuan-Chuan Chao; Lawrence S H Wu; Shiou-Hwei Yeh; Ding-Shinn Chen; Pei-Jer Chen
Clustering of minimal deleted regions reveals distinct genetic pathways of human hepatocellular carcinoma.
Cancer research 2004;64(9):3030-6.
2004: Tae Woo Kim; Jin Hyup Lee; Chien-Fu Hung; Shiwen Peng; Richard B S Roden; Mei-Cheng Wang; Raphael P Viscidi; Ya-Chea Tsai; Liangmei He; Pei-Jer Chen; David A K Boyd; Tzyy-choou Wu
Generation and characterization of DNA vaccines targeting the nucleocapsid protein of severe acute respiratory syndrome coronavirus.
Journal of virology 2004;78(9):4638-45.
2004: Bing-Fang Chen; Jia-Horng Kao; Chun-Jen Liu; Ding-Shinn Chen; Pei-Jer Chen
Genotypic dominance and novel recombinations in HBV genotype B and C co-infected intravenous drug users.
Journal of medical virology 2004;73(1):13-22.
2004: Wan-Fen Kuang; Yu-Chieh Lin; François Jean; Yu-Wen Huang; Chun-Ling Tai; Ding-Shinn Chen; Pei-Jer Chen; Lih-Hwa Hwang
Hepatitis C virus NS3 RNA helicase activity is modulated by the two domains of NS3 and NS4A.
Biochemical and biophysical research communications 2004;317(1):211-7.
2004: Chun-Jen Liu; Jia-Horng Kao; Ming-Yang Lai; Pei-Jer Chen; Ding-Shinn Chen
Precore/core promoter mutations and genotypes of hepatitis B virus in chronic hepatitis B patients with fulminant or subfulminant hepatitis.
Journal of medical virology 2004;72(4):545-50.
2004: Jhy-Shrian Huang; Chuan-Chuan Chao; Teh-Li Su; Shiou-Hwei Yeh; Ding-Shinn Chen; Chiung-Tong Chen; Pei-Jer Chen; Yuh-Shan Jou
Diverse cellular transformation capability of overexpressed genes in human hepatocellular carcinoma.
Biochemical and biophysical research communications 2004;315(4):950-8.
2004: Po-Ren Hsueh; Pei-Jer Chen; Cheng-Hsiang Hsiao; Shiou-Hwei Yeh; Wern-Cherng Cheng; Jiun-Ling Wang; Bor-Luen Chiang; Shan-Chwen Chang; Feng-Yee Chang; Wing-Wai Wong; Chuan-Liang Kao; Pan-Chyr Yang
Patient data, early SARS epidemic, Taiwan.
Emerging infectious diseases 2004;10(3):489-93.
2004: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Hepatitis B virus genotypes and spontaneous hepatitis B e antigen seroconversion in Taiwanese hepatitis B carriers.
Journal of medical virology 2004;72(3):363-9.
2004: Shiou-Hwei Yeh; Hurng-Yi Wang; Ching-Yi Tsai; Chuan-Liang Kao; Jyh-Yuan Yang; Hwan-Wun Liu; Ih-Jen Su; Shih-Feng Tsai; Ding-Shinn Chen; Pei-Jer Chen
Characterization of severe acute respiratory syndrome coronavirus genomes in Taiwan: molecular epidemiology and genome evolution.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(8):2542-7.
2004: Jung-Jung Mu; Yeou-Guang Tsay; Li-Jung Juan; Tsai-Feng Fu; Wen-Hung Huang; Ding-Shinn Chen; Pei-Jer Chen
The small delta antigen of hepatitis delta virus is an acetylated protein and acetylation of lysine 72 may influence its cellular localization and viral RNA synthesis.
Virology 2004;319(1):60-70.
2004: Chih-Lin Lin; Li-Ying Liao; Chaur-Shine Wang; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen; Jia-Horng Kao
Evolution of hepatitis B virus precore/basal core promoter gene in HBeAg-positive chronic hepatitis B patients receiving lamivudine therapy.
Liver international : official journal of the International Association for the Study of the Liver 2004;24(1):9-15.
2004: Tae Woo Kim; Chien-Fu Hung; Jeong Won Kim; Jeremy Juang; Pei-Jer Chen; Liangmei He; David A K Boyd; Tzyy-choou Wu
Vaccination with a DNA vaccine encoding herpes simplex virus type 1 VP22 linked to antigen generates long-term antigen-specific CD8-positive memory T cells and protective immunity.
Human gene therapy 2004;15(2):167-77.
2004: Jin-De Chen; Chun-Jen Liu; Po-Huang Lee; Pei-Jer Chen; Ming-Yang Lai; Jia-Horng Kao; Ding-Shinn Chen
Hepatitis B genotypes correlate with tumor recurrence after curative resection of hepatocellular carcinoma.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2004;2(1):64-71.
2004: Ren-Shiang Lee; Shih-Jer Hsu; Li-Rung Huang; Hui-Lin Wu; Shiou-Lin Lin; Ding-Shinn Chen; Pei-Jer Chen
Induction of humoral and cellular immune responses to hepatitis delta virus through DNA immunization in BALB/c mice.
Methods in molecular medicine 2004;96():111-28.
2003: Ming-Tseh Lin; Barry Storer; Paul J Martin; LH Tseng; Ted Gooley; Pei-Jer Chen; John A Hansen
Relation of an interleukin-10 promoter polymorphism to graft-versus-host disease and survival after hematopoietic-cell transplantation.
The New England journal of medicine 2003;349(23):2201-10.
2003: Ming-Whei Yu; Hung-Chuen Chang; Shun-Chiao Chang; Yun-Fan Liaw; Shi-Ming Lin; Chun-Jen Liu; Shou-Dong Lee; Chih-Lin Lin; Pei-Jer Chen; Shee-Chan Lin; Chien-Jen Chen
Role of reproductive factors in hepatocellular carcinoma: Impact on hepatitis B- and C-related risk.
Hepatology (Baltimore, Md.) 2003;38(6):1393-400.
2003: Chi-Tai Fang; Pei-Jer Chen; Mao-Yuan Chen; Chien-Ching Hung; Shan-Chwen Chang; An-Lung Chang; Ding-Shinn Chen
Dynamics of plasma hepatitis B virus levels after highly active antiretroviral therapy in patients with HIV infection.
Journal of hepatology 2003;39(6):1028-35.
2003: Ming-Whei Yu; Shi-Yi Yang; I-Jen Pan Castle; Chih-Lin Lin; Chun-Jen Liu; Yun-Fan Liaw; Shi-Ming Lin; Pei-Jer Chen; Shou-Dong Lee; Chien-Jen Chen
Polymorphisms in XRCC1 and glutathione S-transferase genes and hepatitis B-related hepatocellular carcinoma.
Journal of the National Cancer Institute 2003;95(19):1485-8.
2003: Po-Ren Hsueh; Cheng-Hsiang Hsiao; Shiou-Hwei Yeh; Wei-Kung Wang; Pei-Jer Chen; Jann-Tay Wang; Shan-Chwen Chang; Chuan-Liang Kao; Pan-Chyr Yang
Microbiologic characteristics, serologic responses, and clinical manifestations in severe acute respiratory syndrome, Taiwan.
Emerging infectious diseases 2003;9(9):1163-7.
2003: Tong-Yuan Tai; Jin-Ying Lu; Chi-Ling Chen; Ming-Yang Lai; Pei-Jer Chen; Jia-Horng Kao; Cha-Ze Lee; H-S Lee; Lee-Ming Chuang; Yung-Ming Jeng
Interferon-alpha reduces insulin resistance and beta-cell secretion in responders among patients with chronic hepatitis B and C.
The Journal of endocrinology 2003;178(3):457-65.
2003: Shiou-Hwei Yeh; Ding-Shinn Chen; Pei-Jer Chen
A prospect for pharmacogenomics in the interferon therapy of chronic viral hepatitis.
The Journal of antimicrobial chemotherapy 2003;52(2):149-51.
2003: Chun-Jen Liu; Pei-Jer Chen; Wen-Yi Shau; Jia-Horng Kao; Ming-Yang Lai; Ding-Shinn Chen
Clinical aspects and outcomes of volunteer blood donors testing positive for hepatitis-C virus infection in Taiwan: a prospective study.
Liver international : official journal of the International Association for the Study of the Liver 2003;23(3):148-55.
2003: Ann-Lii Cheng; Chao A Hsiung; Ih-Jen Su; Pei-Jer Chen; Ming-Chih Chang; Chao-Jung Tsao; Woei-Yau Kao; Wu-Ching Uen; Chih-Hung Hsu; Hwei-Fang Tien; Tsu-Yi Chao; Li-Tzong Chen; Jacqueline Whang-Peng
Steroid-free chemotherapy decreases risk of hepatitis B virus (HBV) reactivation in HBV-carriers with lymphoma.
Hepatology (Baltimore, Md.) 2003;37(6):1320-8.
2003: Kuo-Feng Tai; Pei-Jer Chen; Ding-Shinn Chen; Lih-Hwa Hwang
Concurrent delivery of GM-CSF and endostatin genes by a single adenoviral vector provides a synergistic effect on the treatment of orthotopic liver tumors.
The journal of gene medicine 2003;5(5):386-98.
2003: Chun-Jen Liu; Pei-Jer Chen; Ming-Yang Lai; Jia-Horng Kao; Yung-Ming Jeng; Ding-Shinn Chen
Ribavirin and interferon is effective for hepatitis C virus clearance in hepatitis B and C dually infected patients.
Hepatology (Baltimore, Md.) 2003;37(3):568-76.
2003: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Basal core promoter mutations of hepatitis B virus increase the risk of hepatocellular carcinoma in hepatitis B carriers.
Gastroenterology 2003;124(2):327-34.
2003: Jia-Horng Kao; Wendy Chen; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
SEN virus infection in patients with chronic hepatitis C: preferential coinfection with hepatitis C genotype 2a and no effect on response to therapy with interferon plus ribavirin.
The Journal of infectious diseases 2003;187(2):307-10.
2003: Chun-Jen Liu; Pei-Jer Chen; Ming-Yang Lai; Jia-Horng Kao; Ching-Fung Chang; Hui-Lin Wu; Wen-Yi Shau; Ding-Shinn Chen
A prospective study characterizing full-length hepatitis B virus genomes during acute exacerbation.
Gastroenterology 2003;124(1):80-90.
2002: Jann-Tay Wang; Cha-Ze Lee; Pei-Jer Chen; Teh-Hong Wang; Ding-Shinn Chen
Transfusion-transmitted HBV infection in an endemic area: the necessity of more sensitive screening for HBV carriers.
Transfusion 2002;42(12):1592-7.
2002: Jennifer K King; Shiou-Hwei Yeh; Ming-Wei Lin; Chun-Jen Liu; Ming-Yang Lai; Jia-Horng Kao; Ding-Shinn Chen; Pei-Jer Chen
Genetic polymorphisms in interferon pathway and response to interferon treatment in hepatitis B patients: A pilot study.
Hepatology (Baltimore, Md.) 2002;36(6):1416-24.
2002: Daw-Jen Tsuei; Mei-Hwei Chang; Pei-Jer Chen; Tsuey-Ying Hsu; Yen-Hsuan Ni
Characterization of integration patterns and flanking cellular sequences of hepatitis B virus in childhood hepatocellular carcinomas.
Journal of medical virology 2002;68(4):513-21.
2002: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Occult hepatitis B virus infection and clinical outcomes of patients with chronic hepatitis C.
Journal of clinical microbiology 2002;40(11):4068-71.
2002: Ming-Whei Yu; Hung-Chuen Chang; Pei-Jer Chen; Chun-Jen Liu; Yun-Fan Liaw; Shi-Ming Lin; Shou-Dong Lee; Shee-Chan Lin; Chih-Lin Lin; Chien-Jen Chen
Increased risk for hepatitis B-related liver cirrhosis in relatives of patients with hepatocellular carcinoma in northern Taiwan.
International journal of epidemiology 2002;31(5):1008-15.
2002: Ya-Wen Chen; Yung-Ming Jeng; Shiou-Hwei Yeh; Pei-Jer Chen
P53 gene and Wnt signaling in benign neoplasms: beta-catenin mutations in hepatic adenoma but not in focal nodular hyperplasia.
Hepatology (Baltimore, Md.) 2002;36(4 Pt 1):927-35.
2002: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Sequence analysis of pre-S/surface and pre-core/core promoter genes of hepatitis B virus in chronic hepatitis C patients with occult HBV infection.
Journal of medical virology 2002;68(2):216-20.
2002: Yann-Jang Chen; Pei-Jer Chen; Mei-Chi Lee; Shiou-Hwei Yeh; Ming-Ta Hsu; Chi-Hung Lin
Chromosomal analysis of hepatic adenoma and focal nodular hyperplasia by comparative genomic hybridization.
Genes, chromosomes & cancer 2002;35(2):138-43.
2002: LH Tseng; Pei-Jer Chen; Ming-Tseh Lin; Kentner Singleton; Emily G Martin; Ai-Hsin Yen; Paul J Martin; John A Hansen
Simultaneous genotyping of single nucleotide polymorphisms in the IL-1 gene complex by multiplex polymerase chain reaction-restriction fragment length polymorphism.
Journal of immunological methods 2002;267(2):151-6.
2002: Chi-Wu Chen; Yeou-Guang Tsay; Hui-Lin Wu; Chi-Hua Lee; Ding-Shinn Chen; Pei-Jer Chen
The double-stranded RNA-activated kinase, PKR, can phosphorylate hepatitis D virus small delta antigen at functional serine and threonine residues.
The Journal of biological chemistry 2002;277(36):33058-67.
2002: Chun-Jen Liu; Jia-Horng Kao; Wen-Yi Shau; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Naturally occurring hepatitis B surface gene variants in chronic hepatitis B virus infection: correlation with viral serotypes and clinical stages of liver disease.
Journal of medical virology 2002;68(1):50-9.
2002: Shiou-Hwei Yeh; Ching-Fung Chang; Wen-Yi Shau; Ya-Wen Chen; Hey-Chi Hsu; Po-Huang Lee; Ding-Shinn Chen; Pei-Jer Chen
Dominance of functional androgen receptor allele with longer CAG repeat in hepatitis B virus-related female hepatocarcinogenesis.
Cancer research 2002;62(15):4346-51.
2002: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Hepatitis D virus genotypes in intravenous drug users in taiwan: decreasing prevalence and lack of correlation with hepatitis B virus genotypes.
Journal of clinical microbiology 2002;40(8):3047-9.
2002: Hwai-I Yang; Sheng-Nan Lu; Yun-Fan Liaw; San-Lin You; Chien-An Sun; Li-Yu Wang; Chuhsing Kate Hsiao; Pei-Jer Chen; Ding-Shinn Chen; Chien-Jen Chen
Hepatitis B e antigen and the risk of hepatocellular carcinoma.
The New England journal of medicine 2002;347(3):168-74.
2002: Ming-Whei Yu; Yu-Ching Yang; Shi-Yi Yang; Hung-Chuen Chang; Yun-Fan Liaw; Shi-Ming Lin; Chun-Jen Liu; Shou-Dong Lee; Chih-Lin Lin; Pei-Jer Chen; Shee-Chan Lin; Chien-Jen Chen
Androgen receptor exon 1 CAG repeat length and risk of hepatocellular carcinoma in women.
Hepatology (Baltimore, Md.) 2002;36(1):156-63.
2002: Chee-Huan Pan; Pei-Ming Yang; Lih-Hwa Hwang; Shing-F Kao; Pei-Jer Chen; Bor-Luen Chiang; Ding-Shinn Chen
T-cell antigenic determinants within hepatitis C virus nonstructural protein 3 and cytokine production profiles in hepatitis C.
Journal of viral hepatitis 2002;9(4):258-64.
2002: LH Tseng; Pei-Jer Chen; Ming-Tseh Lin; Kentner Singleton; Emily G Martin; A-H Yen; Sou-Ming Chuang; Paul J Martin; John A Hansen
Simultaneous genotyping of single nucleotide polymorphisms in the IL-6, IL-10, TNFalpha and TNFbeta genes.
Tissue antigens 2002;59(4):280-6.
2002: Jenq-Yuh Ko; Tso-Ching Lee; Chin-Fu Hsiao; Guan-Lu Lin; Sang-Hue Yen; Kuang Y Chen; Chao A Hsiung; Pei-Jer Chen; Mow-Ming Hsu; Yuh-Shan Jou
Definition of three minimal deleted regions by comprehensive allelotyping and mutational screening of FHIT,p16(INK4A), and p19(ARF) genes in nasopharyngeal carcinoma.
Cancer 2002;94(7):1987-96.
2002: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Genotypes and clinical phenotypes of hepatitis B virus in patients with chronic hepatitis B virus infection.
Journal of clinical microbiology 2002;40(4):1207-9.
2002: C J Liu; J H Kao; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Molecular epidemiology of hepatitis B viral serotypes and genotypes in taiwan.
Journal of biomedical science 2002;9(2):166-70.
2002: Jia-Horng Kao; Wendy Chen; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Prevalence and implication of a newly identified infectious agent (SEN virus) in Taiwan.
The Journal of infectious diseases 2002;185(3):389-92.
2002: Chih-Lin Lin; Li-Ying Liao; Chun-Jen Liu; Pei-Jer Chen; Ming-Yang Lai; Jia-Horng Kao; Ding-Shinn Chen
Hepatitis B genotypes and precore/basal core promoter mutants in HBeAg-negative chronic hepatitis B.
Journal of gastroenterology 2002;37(4):283-7.
2002: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Clinical and virological aspects of blood donors infected with hepatitis B virus genotypes B and C.
Journal of clinical microbiology 2002;40(1):22-5.
2001: Jia-Horng Kao; Ming-Yang Lai; Pei-Jer Chen; Ding-Shinn Chen
Probable reinfection with hepatitis C virus in a chronic hepatitis C patient with a sustained response to combination therapy.
Journal of the Formosan Medical Association = Taiwan yi zhi 2001;100(12):824-8.
2001: SH Fang; Ming-Yang Lai; Lih-Hwa Hwang; Pei-Ming Yang; Pei-Jer Chen; Bor-Luen Chiang; Ding-Shinn Chen
Ribavirin enhances interferon-gamma levels in patients with chronic hepatitis C treated with interferon-alpha.
Journal of biomedical science 2001;8(6):484-91.
2001: H L Wu; Pei-Jer Chen; H K Lin; R S Lee; H L Lin; Chun-Jen Liu; P J Lee; J J Lee; Ding-Shinn Chen
Molecular cloning and expression of woodchuck granulocyte-macrophage colony stimulating factor.
Journal of medical virology 2001;65(3):567-75.
2001: Jia-Horng Kao; Ming-Yang Lai; Pei-Jer Chen; Y M Cheng; Ding-Shinn Chen
Prolonged interferon treatment after combination interferon and ribavirin therapy in patients with chronic hepatitis C: a clinical trial of interferon relapsers and non-responders.
Journal of the Formosan Medical Association = Taiwan yi zhi 2001;100(10):662-7.
2001: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Acute exacerbations of chronic hepatitis B are rarely associated with superinfection of hepatitis B virus.
Hepatology (Baltimore, Md.) 2001;34(4 Pt 1):817-23.
2001: Jung-Jung Mu; Ding-Shinn Chen; Pei-Jer Chen
The conserved serine 177 in the delta antigen of hepatitis delta virus is one putative phosphorylation site and is required for efficient viral RNA replication.
Journal of virology 2001;75(19):9087-95.
2001: Chun-Jen Liu; Ming-Yang Lai; Po-Huang Lee; Nai-Kuan Chou; Shu-Hsun Chu; Pei-Jer Chen; Jia-Horng Kao; Y M Jen; Ding-Shinn Chen
Lamivudine treatment for hepatitis B reactivation in HBsAg carriers after organ transplantation: a 4-year experience.
Journal of gastroenterology and hepatology 2001;16(9):1001-8.
2001: Chun-Jen Liu; Pei-Jer Chen; Ming-Yang Lai; Jia-Horng Kao; Ding-Shinn Chen
Hepatitis B virus variants in patients receiving lamivudine treatment with breakthrough hepatitis evaluated by serial viral loads and full-length viral sequences.
Hepatology (Baltimore, Md.) 2001;34(3):583-9.
2001: Shiou-Hwei Yeh; Pei-Jer Chen; Wen-Yi Shau; Ya-Wen Chen; Po-Huang Lee; J T Chen; Ding-Shinn Chen
Chromosomal allelic imbalance evolving from liver cirrhosis to hepatocellular carcinoma.
Gastroenterology 2001;121(3):699-709.
2001: LH Tseng; Pei-Jer Chen; Ming-Tseh Lin; Wen-Yi Shau; S M Chaung; Paul J Martin; John A Hansen
Single nucleotide polymorphisms in intron 2 of the human interleukin-1 receptor antagonist (IL-1Ra) gene: further definition of the IL-1 beta and IL-1Ra polymorphisms in North American Caucasians and Taiwanese Chinese.
Tissue antigens 2001;57(4):318-24.
2000: Ming-Whei Yu; S W Cheng; M W Lin; Shi-Yi Yang; Yun-Fan Liaw; Hong-Chiang Chang; Tun-Jen Hsiao; Shi-Ming Lin; Shou-Dong Lee; Pei-Jer Chen; Chun-Jen Liu; Chien-Jen Chen
Androgen-receptor gene CAG repeats, plasma testosterone levels, and risk of hepatitis B-related hepatocellular carcinoma.
Journal of the National Cancer Institute 2000;92(24):2023-8.
2000: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Efficacy of consensus interferon in the treatment of chronic hepatitis C.
Journal of gastroenterology and hepatology 2000;15(12):1418-23.
2000: Jia-Horng Kao; NH Wu; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Hepatitis B genotypes and the response to interferon therapy.
Journal of hepatology 2000;33(6):998-1002.
2000: Mao-Hsien Wang; Chen-Tu Wu; Chien-Ching Hung; Ja-Der Liang; Pei-Jer Chen
Hepatic leiomyomatous neoplasm associated with Epstein Barr virus infection in an adult with acquired immunodeficiency syndrome.
Journal of the Formosan Medical Association = Taiwan yi zhi 2000;99(11):873-5.
2000: Chun-Jen Liu; Jia-Horng Kao; Wendy Chen; R J Tsai; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Interspousal transmission of TT virus: low efficiency and lack of apparent risk factors.
Journal of gastroenterology and hepatology 2000;15(11):1287-91.
2000: Ming-Whei Yu; C I Pai; Shi-Yi Yang; Tun-Jen Hsiao; Hong-Chiang Chang; Shi-Ming Lin; Yun-Fan Liaw; Pei-Jer Chen; Chien-Jen Chen
Role of N-acetyltransferase polymorphisms in hepatitis B related hepatocellular carcinoma: impact of smoking on risk.
Gut 2000;47(5):703-9.
2000: Yann-Jang Chen; Shiou-Hwei Yeh; J T Chen; C C Wu; Ming-Ta Hsu; Shih-Feng Tsai; Pei-Jer Chen; Chi Hong Lin
Chromosomal changes and clonality relationship between primary and recurrent hepatocellular carcinoma.
Gastroenterology 2000;119(2):431-40.
2000: Ming-Whei Yu; Hong-Chiang Chang; Yun-Fan Liaw; Shi-Ming Lin; Shou-Dong Lee; Chun-Jen Liu; Pei-Jer Chen; Tun-Jen Hsiao; Po-Huang Lee; Chien-Jen Chen
Familial risk of hepatocellular carcinoma among chronic hepatitis B carriers and their relatives.
Journal of the National Cancer Institute 2000;92(14):1159-64.
2000: Jia-Horng Kao; Chun-Jen Liu; Pei-Jer Chen; Wendy Chen; Ming-Yang Lai; Ding-Shinn Chen
Low incidence of hepatitis C virus transmission between spouses: a prospective study.
Journal of gastroenterology and hepatology 2000;15(4):391-5.
2000: Jia-Horng Kao; Wendy Chen; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
TT virus infection in patients with chronic hepatitis B or C: influence on clinical, histological and virological features.
Journal of medical virology 2000;60(4):387-92.
2000: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B.
Gastroenterology 2000;118(3):554-9.
2000: S F Tsai; Pei-Jer Chen
Impact of human genome research on medicine--the initial Taiwan experience.
Journal of the Formosan Medical Association = Taiwan yi zhi 2000;99(2):107-15.
1999: Jung-Jung Mu; Hui-Lin Wu; B L Chiang; R P Chang; Ding-Shinn Chen; Pei-Jer Chen
Characterization of the phosphorylated forms and the phosphorylated residues of hepatitis delta virus delta antigens.
Journal of virology 1999;73(12):10540-5.
1999: Jia-Horng Kao; Wendy Chen; SC Hsiang; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Prevalence and implication of TT virus infection: minimal role in patients with non-A-E hepatitis in Taiwan.
Journal of medical virology 1999;59(3):307-12.
1999: Yen-Hsuan Ni; Hong-Yuan Hsu; Pei-Jer Chen; Mei-Hwei Chang
Protamine enhances the efficiency of liposome-mediated gene transfer in a cultured human hepatoma cell line.
Journal of the Formosan Medical Association = Taiwan yi zhi 1999;98(8):562-6.
1999: C Chen; Y M Tsang; Po-Ren Hsueh; G T Huang; Pei-Ming Yang; J C Sheu; Ming-Yang Lai; Pei-Jer Chen; Ding-Shinn Chen
Bacterial infections associated with hepatic arteriography and transarterial embolization for hepatocellular carcinoma: a prospective study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1999;29(1):161-6.
1999: Yann-Jang Chen; J Y Ko; Pei-Jer Chen; Chih-Hung Shu; Ming-Ta Hsu; Shih-Feng Tsai; Chi Hong Lin
Chromosomal aberrations in nasopharyngeal carcinoma analyzed by comparative genomic hybridization.
Genes, chromosomes & cancer 1999;25(2):169-75.
1999: Yen-Hsuan Ni; Mei-Hwei Chang; Pei-Jer Chen; Hong-Yuan Hsu; Tung-Wu Lu; K H Lin; D T Lin
Decreased diversity of hepatitis C virus quasispecies during bone marrow transplantation.
Journal of medical virology 1999;58(2):132-8.
1999: Jia-Horng Kao; M Wood; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Comparison of two methods for quantification of hepatitis B viral DNA.
Journal of gastroenterology and hepatology 1999;14(5):423-6.
1999: Chun-Jen Liu; Jia-Horng Kao; Ming-Yang Lai; Pei-Jer Chen; J S Chu; Wendy Chen; Ding-Shinn Chen
Minimal role of GB virus-C/hepatitis G virus in fulminant and subfulminant hepatitis in Taiwan.
Journal of gastroenterology and hepatology 1999;14(4):352-7.
1999: Pu Ou-Yang; Bor-Luen Chiang; Lih-Hwa Hwang; Y G Chen; Pei-Ming Yang; Wei-Kuang Chi; Pei-Jer Chen; Ding-Shinn Chen
Characterization of monoclonal antibodies against hepatitis C virus nonstructural protein 3: different antigenic determinants from human B cells.
Journal of medical virology 1999;57(4):345-50.
1999: Jia-Horng Kao; Wendy Chen; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Liver and peripheral blood mononuclear cells are not major sites for GB virus-C/hepatitis G virus replication.
Archives of virology 1999;144(11):2173-83.
1999: Y G Chang; Pei-Jer Chen; Chien-Ching Hung; Mao-Yuan Chen; Ming-Yang Lai; Ding-Shinn Chen
Opportunistic hepatic infections in AIDS patients with fever of unknown origin.
Journal of the Formosan Medical Association = Taiwan yi zhi 1999;98(1):5-10.
1998: Jia-Horng Kao; Ming-Yang Lai; Wendy Chen; Pei-Jer Chen; Ding-Shinn Chen
Efficacy of ribavirin plus interferon alpha on viraemia of GB virus-C/hepatitis G virus: comparison with interferon alpha alone.
Journal of gastroenterology and hepatology 1998;13(12):1249-53.
1998: Hui-Ling Chen; H L Wu; C C Fon; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Long-term culture of hepatocytes from human adults.
Journal of biomedical science 1998;5(6):435-40.
1998: J L Tang; Hwei-Fang Tien; MT Lin; Pei-Jer Chen; Yee-Chun Chen
P53 mutation in advanced stage of primary myelodysplastic syndrome.
Anticancer research 1998;18(5B):3757-61.
1998: Bor-Luen Chiang; Pei-Ming Yang; Lih-Hwa Hwang; J M Wang; S F Kao; Chee-Huan Pan; Wei-Kuang Chi; Pei-Jer Chen; Ding-Shinn Chen
Establishment and characterization of NS3 protein-specific T-cell clones from a patient with chronic hepatitis C.
Journal of biomedical science 1998;5(4):290-6.
1998: Mei-Hwei Chang; Hong-Yuan Hsu; Yen-Hsuan Ni; Keh-Sung Tsai; Ping-Ing Lee; Pei-Jer Chen; Y L Hsu; Ding-Shinn Chen
Precore stop codon mutant in chronic hepatitis B virus infection in children: its relation to hepatitis B e seroconversion and maternal hepatitis B surface antigen.
Journal of hepatology 1998;28(6):915-22.
1998: Ho-Hsiung Lin; Jia-Horng Kao; Kuei-Ying Yeh; D P Liu; Mei-Hwei Chang; Pei-Jer Chen; Ding-Shinn Chen
Mother-to-infant transmission of GB virus C/hepatitis G virus: the role of high-titered maternal viremia and mode of delivery.
The Journal of infectious diseases 1998;177(5):1202-6.
1998: J L Tang; Hwei-Fang Tien; MT Lin; Pei-Jer Chen; Yee-Chun Chen
Frequent p53 mutation in relapsed acute lymphoblastic leukemia with cytogenetic instability: a longitudinal analysis.
Anticancer research 1998;18(2B):1273-8.
1998: Hsuan-Shu Lee; A-Mei Huang; Guan-Tarn Huang; Pei-Ming Yang; Pei-Jer Chen; Jin-Chuan Sheu; Ming-Yang Lai; Sheng-Chung Lee; Chen-Kung Chou; Ding-Shinn Chen
Hepatocyte growth factor stimulates the growth and activates mitogen-activated protein kinase in human hepatoma cells.
Journal of biomedical science 1998;5(3):180-4.
1998: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; Wendy Chen; Ding-Shinn Chen
Effects of GB virus-C/hepatitis G virus on hepatitis B and C viremia in multiple hepatitis virus infections.
Archives of virology 1998;143(4):797-802.
1997: H W Wang; Hui-Lin Wu; Ding-Shinn Chen; Pei-Jer Chen
Identification of the functional regions required for hepatitis D virus replication and transcription by linker-scanning mutagenesis of viral genome.
Virology 1997;239(1):119-31.
1997: Jia-Horng Kao; Chun-Jen Liu; Pei-Jer Chen; Wendy Chen; SC Hsiang; Ming-Yang Lai; Ding-Shinn Chen
Interspousal transmission of GB virus-C/hepatitis G virus: a comparison with hepatitis C virus.
Journal of medical virology 1997;53(4):348-53.
1997: Huey-Ling Chen; Mei-Hwei Chang; Yen-Hsuan Ni; Hong-Yuan Hsu; Jia-Horng Kao; Pei-Jer Chen
Hepatitis G virus infection in normal and prospectively followed posttransfusion children.
Pediatric research 1997;42(6):784-7.
1997: Pei-Jer Chen; Hui-Lin Wu; C J Wang; J H Chia; Ding-Shinn Chen
Molecular biology of hepatitis D virus: research and potential for application.
Journal of gastroenterology and hepatology 1997;12(9-10):S188-92.
1997: Jia-Horng Kao; Ming-Yang Lai; Pei-Jer Chen; Ding-Shinn Chen
Immunoglobulin M antibody response to hepatitis C virus core protein in patients with chronic hepatitis C.
Journal of the Formosan Medical Association = Taiwan yi zhi 1997;96(10):825-8.
1997: Hui-Lin Wu; Pei-Jer Chen; Jung-Jung Mu; Wei-Kuang Chi; T L Kao; Lih-Hwa Hwang; Ding-Shinn Chen
Assembly of hepatitis delta virus-like empty particles in yeast.
Virology 1997;236(2):374-81.
1997: Jia-Horng Kao; Wendy Chen; Pei-Jer Chen; Ming-Yang Lai; R Y Lin; Ding-Shinn Chen
GB virus-C/hepatitis G virus infection in prostitutes: possible role of sexual transmission.
Journal of medical virology 1997;52(4):381-4.
1997: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; T H Wang; Ding-Shinn Chen
Positive and negative strand of hepatitis C virus RNA sequences in peripheral blood mononuclear cells in patients with chronic hepatitis C: no correlation with viral genotypes 1b, 2a, and 2b.
Journal of medical virology 1997;52(3):270-4.
1997: Yen-Hsuan Ni; Mei-Hwei Chang; Pei-Jer Chen; Hans Hsienhong Lin; Hong-Yuan Hsu
Evolution of hepatitis C virus quasispecies in mothers and infants infected through mother-to-infant transmission.
Journal of hepatology 1997;26(5):967-74.
1997: Woei Tsay; Y M Lee; Sheng-Chung Lee; Ming-Ching Shen; Pei-Jer Chen
Synergistic transactivation of HNF-1alpha, HNF-3, and NF-I contributes to the activation of the liver-specific protein C gene.
DNA and cell biology 1997;16(5):569-77.
1997: Chun-Jen Liu; Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; Tsui-Lien Mao; Teh-Hong Wang; Ding-Shinn Chen
Benign recurrent intrahepatic cholestasis.
Journal of the Formosan Medical Association = Taiwan yi zhi 1997;96(5):370-3.
1997: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; Wendy Chen; D P Liu; Jann-Tay Wang; Ming-Ching Shen; Ding-Shinn Chen
GB virus-C/hepatitis G virus infection in an area endemic for viral hepatitis, chronic liver disease, and liver cancer.
Gastroenterology 1997;112(4):1265-70.
1997: Jia-Horng Kao; Pei-Jer Chen; Wendy Chen; SC Hsiang; Ming-Yang Lai; Ding-Shinn Chen
Amplification of GB virus-C/hepatitis G virus RNA with primers from different regions of the viral genome.
Journal of medical virology 1997;51(4):284-9.
1996: Jia-Horng Kao; Ming-Yang Lai; Pei-Jer Chen; Lih-Hwa Hwang; Ding-Shinn Chen
Serum hepatitis C virus titers in the progression of type C chronic liver disease. With special emphasis on patients with type 1b infection.
Journal of clinical gastroenterology 1996;23(4):280-3.
1996: Jia-Horng Kao; Pei-Jer Chen; J T Wang; Pei-Ming Yang; Ming-Yang Lai; Teh-Hong Wang; Ding-Shinn Chen
Superinfection by homotypic virus in hepatitis C virus carriers: studies on patients with post-transfusion hepatitis.
Journal of medical virology 1996;50(4):303-8.
1996: Ming-Yang Lai; Jia-Horng Kao; Pei-Ming Yang; J T Wang; Pei-Jer Chen; K W Chan; Jan-Show Chu; Ding-Shinn Chen
Long-term efficacy of ribavirin plus interferon alfa in the treatment of chronic hepatitis C.
Gastroenterology 1996;111(5):1307-12.
1996: Jia-Horng Kao; Y T Hwang; Pei-Jer Chen; Pei-Ming Yang; Ming-Yang Lai; Teh-Hong Wang; Ding-Shinn Chen
Transmission of hepatitis C virus between spouses: the important role of exposure duration.
The American journal of gastroenterology 1996;91(10):2087-90.
1996: M T Lin; Y C Yang; Pei-Jer Chen; J I Tang; LH Tseng; C W Wang; Yee-Chun Chen
Subtyping of human T-lymphotropic virus type I by amplification of long terminal repeat sequences and restriction fragment length polymorphism analysis in carriers with multiple transfusions.
Annals of hematology 1996;73(3):127-34.
1996: J T Wang; F C Tsai; Cha-Ze Lee; Pei-Jer Chen; Jin-Chuan Sheu; Teh-Hong Wang; Ding-Shinn Chen
A prospective study of transfusion-transmitted GB virus C infection: similar frequency but different clinical presentation compared with hepatitis C virus.
Blood 1996;88(5):1881-6.
1996: Y T Hwang; Pei-Jer Chen; Jia-Horng Kao; T D Wang; H H Wang; Jan-Show Chu; I J Su; Ding-Shinn Chen
Rapid hepatic failure associated with a contracted liver mimicking cirrhosis in a case of nasopharyngeal carcinoma with liver metastasis.
Liver 1996;16(4):283-7.
1996: Jia-Horng Kao; Pei-Jer Chen; S C Hsiang; Wendy Chen; Ding-Shinn Chen
Phylogenetic analysis of GB virus C: comparison of isolates from Africa, North America, and Taiwan.
The Journal of infectious diseases 1996;174(2):410-3.
1996: Lih-Hwa Hwang; Pei-Ming Yang; Ming-Yang Lai; Bor-Luen Chiang; Jia-Horng Kao; J T Wang; S Y Lee; H M Chian; Wei-Kuang Chi; Y D Chu; Pei-Jer Chen; Ding-Shinn Chen
Identification of humoral antigenic determinants in the hepatitis C virus NS3 protein.
The Journal of infectious diseases 1996;174(1):173-6.
1996: Jia-Horng Kao; Pei-Jer Chen; Pei-Ming Yang; Ming-Yang Lai; Teh-Hong Wang; Ding-Shinn Chen
Absence of extensive genetic heterogeneity of hepatitis C virus in antibody-negative chronic hepatitis C.
Journal of medical virology 1996;49(2):87-90.
1996: Ho-Hsiung Lin; Jia-Horng Kao; M Mizokami; Su-Cheng Huang; Pei-Jer Chen; Ding-Shinn Chen
Serotypes, genotypes and levels of hepatitis C viremia in pregnant women in Taiwan.
Journal of the Formosan Medical Association = Taiwan yi zhi 1996;95(6):429-34.
1996: C J Wang; S Y Sung; Ding-Shinn Chen; Pei-Jer Chen
N-linked glycosylation of hepatitis B surface antigens is involved but not essential in the assembly of hepatitis delta virus.
Virology 1996;220(1):28-36.
1996: Jia-Horng Kao; Ho-Hsiung Lin; Pei-Jer Chen; Ming-Yang Lai; Teh-Hong Wang; M Mizokami; Ding-Shinn Chen
Serotyping of hepatitis C virus in chronic type C hepatitis in Taiwan: correlation with genotypes.
Journal of gastroenterology 1996;31(2):224-7.
1996: Jia-Horng Kao; Ming-Yang Lai; Pei-Jer Chen; Lih-Hwa Hwang; Wendy Chen; Ding-Shinn Chen
Clinical significance of serum hepatitis C virus titers in patients with chronic type C hepatitis.
The American journal of gastroenterology 1996;91(3):506-10.
1996: Yen-Hsuan Ni; Mei-Hwei Chang; K H Lin; Pei-Jer Chen; Dong-Tsamn Lin; Hong-Yuan Hsu; Ding-Shinn Chen
Hepatitis C viral infection in thalassemic children: clinical and molecular studies.
Pediatric research 1996;39(2):323-8.
1996: M T Lin; Yee-Chun Chen; Pei-Jer Chen; Y C Yang; J L Tang; J M Wu; Shuang-En Chuang; Czau-Siung Yang
Envelope gene sequences of human T-lymphotropic virus type 1 in Taiwan.
Archives of virology 1996;141(2):219-29.
1996: Jia-Horng Kao; Ming-Yang Lai; Y T Hwang; Pei-Ming Yang; Pei-Jer Chen; Jin-Chuan Sheu; Teh-Hong Wang; H C Hsu; Ding-Shinn Chen
Chronic hepatitis C without anti-hepatitis C antibodies by second-generation assay. A clinicopathologic study and demonstration of the usefulness of a third-generation assay.
Digestive diseases and sciences 1996;41(1):161-5.
1996: S H Yeh; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Allelic loss on chromosomes 4q and 16q in hepatocellular carcinoma: association with elevated alpha-fetoprotein production.
Gastroenterology 1996;110(1):184-92.
1995: Ho-Hsiung Lin; Jia-Horng Kao; Su-Cheng Huang; TY Lee; Pei-Jer Chen; Ding-Shinn Chen
Prevalence, genotypes and antibody titer of hepatitis C virus in pregnant women in Taiwan.
Journal of obstetrics and gynaecology (Tokyo, Japan) 1995;21(6):557-62.
1995: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; P M Yang; J C Sheu; Teh-Hong Wang; Ding-Shinn Chen
Genotypes of hepatitis C virus in Taiwan and the progression of liver disease.
Journal of clinical gastroenterology 1995;21(3):233-7.
1995: Cha-Ze Lee; Pei-Jer Chen; Ding-Shinn Chen
Large hepatitis delta antigen in packaging and replication inhibition: role of the carboxyl-terminal 19 amino acids and amino-terminal sequences.
Journal of virology 1995;69(9):5332-6.
1995: Pei-Ming Yang; Lih-Hwa Hwang; Ming-Yang Lai; W L Huang; Y D Chu; Wei-Kuang Chi; Bor-Luen Chiang; Jia-Horng Kao; Pei-Jer Chen; Ding-Shinn Chen
Prominent proliferative response of peripheral blood mononuclear cells to a recombinant non-structural (NS3) protein of hepatitis C virus in patients with chronic hepatitis C.
Clinical and experimental immunology 1995;101(2):272-7.
1995: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; Teh-Hong Wang; Ding-Shinn Chen
Quasispecies of hepatitis C virus and genetic drift of the hypervariable region in chronic type C hepatitis.
The Journal of infectious diseases 1995;172(1):261-4.
1995: Shwu-Bin Lin; S S Huang; Kong-Bung Choo; Pei-Jer Chen; Lo-Chun Au
Inhibition of alpha-fetoprotein production in a hepatoma cell line by antisense oligonucleotide analogues.
Journal of biochemistry 1995;117(5):1100-4.
1995: Hong-Yuan Hsu; Mei-Hwei Chang; C Y Lee; K H Hsieh; Yen-Hsuan Ni; Pei-Jer Chen; Ding-Shinn Chen
Precore mutant of hepatitis B virus in childhood fulminant hepatitis B: an infrequent association.
The Journal of infectious diseases 1995;171(4):776-81.
1995: Ho-Hsiung Lin; Jia-Horng Kao; Hong-Yuan Hsu; Yen-Hsuan Ni; Mei-Hwei Chang; Su-Cheng Huang; Lih-Hwa Hwang; Pei-Jer Chen; Ding-Shinn Chen
Absence of infection in breast-fed infants born to hepatitis C virus-infected mothers.
The Journal of pediatrics 1995;126(4):589-91.
1995: Jia-Horng Kao; Pei-Ming Yang; Ming-Yang Lai; Pei-Jer Chen; Teh-Hong Wang; Ding-Shinn Chen
Evaluation of third-generation hepatitis C antibody assay in chronic hepatitis C and chronic non-B, non-C hepatitis.
Viral immunology 1995;8(3):135-9.
1995: C C Wang; Lih-Hwa Hwang; Pei-Ming Yang; Bor-Luen Chiang; Pei-Jer Chen; Ding-Shinn Chen
Unbiased usage of T-cell receptor beta variable region genes in peripheral blood cells of hepatitis C patients: no correlation with superantigen effect.
Journal of medical virology 1995;45(1):24-8.
1994: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; Pei-Ming Yang; Jin-Chuan Sheu; Teh-Hong Wang; Ding-Shinn Chen
Mixed infections of hepatitis C virus as a factor in acute exacerbations of chronic type C hepatitis.
The Journal of infectious diseases 1994;170(5):1128-33.
1994: C H Chen; Pei-Jer Chen; Jan-Show Chu; K H Yeh; Ming-Yang Lai; Ding-Shinn Chen
Fibrosing cholestatic hepatitis in a hepatitis B surface antigen carrier after renal transplantation.
Gastroenterology 1994;107(5):1514-8.
1994: Hui-Wu Wang; Pei-Jer Chen; Cha-Ze Lee; Hui-Lin Wu; Ding-Shinn Chen
Packaging of hepatitis delta virus RNA via the RNA-binding domain of hepatitis delta antigens: different roles for the small and large delta antigens.
Journal of virology 1994;68(10):6363-71.
1994: Mei-Hwei Chang; Yen-Hsuan Ni; Lih-Hwa Hwang; K H Lin; Ho-Hsiung Lin; Pei-Jer Chen; C Y Lee; Ding-Shinn Chen
Long term clinical and virologic outcome of primary hepatitis C virus infection in children: a prospective study.
The Pediatric infectious disease journal 1994;13(9):769-73.
1994: Sun-Lung Tsai; Pei-Jer Chen; Lih-Hwa Hwang; Jia-Horng Kao; J H Huang; T H Chang; Ding-Shinn Chen
Immune response to a hepatitis C virus nonstructural protein in chronic hepatitis C virus infection.
Journal of hepatology 1994;21(3):403-11.
1994: Jia-Horng Kao; Sun-Lung Tsai; Pei-Jer Chen; Pei-Ming Yang; Jin-Chuan Sheu; Ming-Yang Lai; Hey-Chi Hsu; J L Sung; Teh-Hong Wang; Ding-Shinn Chen
A clinicopathologic study of chronic non-A, non-B (type C) hepatitis in Taiwan: comparison between posttransfusion and sporadic patients.
Journal of hepatology 1994;21(2):244-9.
1994: J T Wang; M T Lin; Pei-Jer Chen; Jin-Chuan Sheu; J T Lin; Teh-Hong Wang; Ding-Shinn Chen
Transfusion-transmitted human T-cell lymphotropic virus type I infection in Taiwan: a true risk and occasional coinfection with hepatitis C virus shown in a prospective study.
Blood 1994;84(3):934-40.
1994: Ho-Hsiung Lin; Hong-Yuan Hsu; TY Lee; Rhong-Phong Hsieh; Pei-Jer Chen; Ding-Shinn Chen
Age-specific prevalence of hepatitis B surface and e antigenemia in pregnant women in Taiwan.
Asia-Oceania journal of obstetrics and gynaecology / AOFOG 1994;20(2):141-5.
1994: Yen-Hsuan Ni; Mei-Hwei Chang; Hung-Chi Lue; Hong-Yuan Hsu; M J Wang; Pei-Jer Chen; Ding-Shinn Chen
Posttransfusion hepatitis C virus infection in children.
The Journal of pediatrics 1994;124(5 Pt 1):709-13.
1994: Yen-Hsuan Ni; Ho-Hsiung Lin; Pei-Jer Chen; Hong-Yuan Hsu; Ding-Shinn Chen; Mei-Hwei Chang
Temporal profile of hepatitis C virus antibody and genome in infants born to mothers infected with hepatitis C virus but without human immunodeficiency virus coinfection.
Journal of hepatology 1994;20(5):641-5.
1994: Ho-Hsiung Lin; Jia-Horng Kao; Hong-Yuan Hsu; Yen-Hsuan Ni; S H Yeh; Lih-Hwa Hwang; Mei-Hwei Chang; S C Hwang; Pei-Jer Chen; Ding-Shinn Chen
Possible role of high-titer maternal viremia in perinatal transmission of hepatitis C virus.
The Journal of infectious diseases 1994;169(3):638-41.
1994: Ho-Hsiung Lin; Hong-Yuan Hsu; TY Lee; Jia-Horng Kao; Pei-Jer Chen; Ding-Shinn Chen
Hepatitis C virus infection in pregnant women: detection by different anti-HCV immunoassays and serum HCV-RNA.
Asia-Oceania journal of obstetrics and gynaecology / AOFOG 1994;20(1):13-8.
1994: Cha-Ze Lee; Pei-Jer Chen; M M Lai; Ding-Shinn Chen
Isoprenylation of large hepatitis delta antigen is necessary but not sufficient for hepatitis delta virus assembly.
Virology 1994;199(1):169-75.
1993: F P Tai; Pei-Jer Chen; F J Chang; Ding-Shinn Chen
Hepatitis delta virus cDNA monomer can be used in transfection experiments to initiate viral RNA replication.
Virology 1993;197(1):137-42.
1993: Jia-Horng Kao; Pei-Jer Chen; Ming-Yang Lai; Ding-Shinn Chen
Superinfection of heterologous hepatitis C virus in a patient with chronic type C hepatitis.
Gastroenterology 1993;105(2):583-7.
1993: Ho-Hsiung Lin; Hong-Yuan Hsu; Mei-Hwei Chang; Pei-Jer Chen; Ding-Shinn Chen
Hepatitis B virus in the colostra of HBeAg-positive carrier mothers.
Journal of pediatric gastroenterology and nutrition 1993;17(2):207-10.
1993: Pei-Jer Chen; Lih-Hwa Hwang; L Y Chang; Jia-Horng Kao; Ding-Shinn Chen
Immunoglobulin M antibodies against hepatitis C virus antigens: significance and applications.
Gastroenterologia Japonica 1993;28 Suppl 5():67-70.
1993: Pei-Jer Chen; W J Lai; C J Wang; Ding-Shinn Chen
Hepatitis B surface antigen and large-form hepatitis delta antigen in HDV assembly: a further study.
Progress in clinical and biological research 1993;382():29-34.
1992: Jih-Luh Tang; S H Yeh; Pei-Jer Chen; M T Lin; Hwei-Fang Tien; Yee-Chun Chen
Inactivation of the retinoblastoma gene in acute myelogenous leukaemia.
British journal of haematology 1992;82(3):502-7.
1992: Jia-Horng Kao; Pei-Jer Chen; Pei-Ming Yang; Ming-Yang Lai; Jin-Chuan Sheu; Teh-Hong Wang; Ding-Shinn Chen
Intrafamilial transmission of hepatitis C virus: the important role of infections between spouses.
The Journal of infectious diseases 1992;166(4):900-3.
1992: Ho-Hsiung Lin; Hong-Yuan Hsu; Mei-Hwei Chang; J T Wang; Pei-Jer Chen; Ding-Shinn Chen
Correlation between ELISA and recombinant immunoblot assay in serum samples positive for anti-HCV.
Journal of the Formosan Medical Association = Taiwan yi zhi 1992;91(7):729-30.
1992: Pei-Jer Chen; J T Wang; Lih-Hwa Hwang; Y H Yang; C L Hsieh; Jia-Horng Kao; Jin-Chuan Sheu; Ming-Yang Lai; Teh-Hong Wang; Ding-Shinn Chen
Transient immunoglobulin M antibody response to hepatitis C virus capsid antigen in posttransfusion hepatitis C: putative serological marker for acute viral infection.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(13):5971-5.
1992: Hong-Yuan Hsu; Mei-Hwei Chang; K H Hsieh; C Y Lee; Ho-Hsiung Lin; Lih-Hwa Hwang; Pei-Jer Chen; Ding-Shinn Chen
Cellular immune response to HBcAg in mother-to-infant transmission of hepatitis B virus.
Hepatology (Baltimore, Md.) 1992;15(5):770-6.
1992: Pei-Jer Chen; F L Chang; C J Wang; C J Lin; S Y Sung; Ding-Shinn Chen
Functional study of hepatitis delta virus large antigen in packaging and replication inhibition: role of the amino-terminal leucine zipper.
Journal of virology 1992;66(5):2853-9.
1992: Pei-Jer Chen; M H Lin; K F Tai; P C Liu; C J Lin; Ding-Shinn Chen
The Taiwanese hepatitis C virus genome: sequence determination and mapping the 5' termini of viral genomic and antigenomic RNA.
Virology 1992;188(1):102-13.
1992: Sun-Lung Tsai; Pei-Jer Chen; Ming-Yang Lai; Pei-Ming Yang; J L Sung; J H Huang; Lih-Hwa Hwang; T H Chang; Ding-Shinn Chen
Acute exacerbations of chronic type B hepatitis are accompanied by increased T cell responses to hepatitis B core and e antigens. Implications for hepatitis B e antigen seroconversion.
The Journal of clinical investigation 1992;89(1):87-96.
1991: Hui-Lin Wu; Pei-Jer Chen; M H Lin; Ding-Shinn Chen
Temporal aspects of major viral transcript expression in Hep G2 cells transfected with cloned hepatitis B virus DNA: with emphasis on the X transcript.
Virology 1991;185(2):644-51.
1991: Ho-Hsiung Lin; Hong-Yuan Hsu; Mei-Hwei Chang; K F Hong; Y C Young; TY Lee; Pei-Jer Chen; Ding-Shinn Chen
Low prevalence of hepatitis C virus and infrequent perinatal or spouse infections in pregnant women in Taiwan.
Journal of medical virology 1991;35(4):237-40.
1991: C J Wang; Pei-Jer Chen; J C Wu; D Patel; Ding-Shinn Chen
Small-form hepatitis B surface antigen is sufficient to help in the assembly of hepatitis delta virus-like particles.
Journal of virology 1991;65(12):6630-6.
1991: F L Chang; Pei-Jer Chen; S J Tu; C J Wang; Ding-Shinn Chen
The large form of hepatitis delta antigen is crucial for assembly of hepatitis delta virus.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8490-4.
1991: Ding-Shinn Chen; J T Wang; Pei-Jer Chen; T H Wang; J L Sung
Hepatitis C virus infection in Taiwan.
Gastroenterologia Japonica 1991;26 Suppl 3():164-6.
1991: Pei-Jer Chen; M H Lin; S J Tu; Ding-Shinn Chen
Isolation of a complementary DNA fragment of hepatitis C virus in Taiwan revealed significant sequence variations compared with other isolates.
Hepatology (Baltimore, Md.) 1991;14(1):73-8.
1991: Ho-Hsiung Lin; Rhong-Phong Hsieh; C Y Wang; Pei-Jer Chen; Ding-Shinn Chen
Prevalence of antibody to hepatitis C virus in pregnant Taiwanese.
Journal of the Formosan Medical Association = Taiwan yi zhi 1991;90(5):476-9.
1991: Hui-Lin Wu; Pei-Jer Chen; S J Tu; M H Lin; M Y Lai; Ding-Shinn Chen
Characterization and genetic analysis of alternatively spliced transcripts of hepatitis B virus in infected human liver tissues and transfected HepG2 cells.
Journal of virology 1991;65(4):1680-6.
1991: Ding-Shinn Chen; Ming-Yang Lai; Pei-Jer Chen; J C Sheu; Pei-Ming Yang; J L Sung
Hepatitis D virus infection in a hyperendemic area of chronic hepatitis B virus infection: the Taiwan experience.
Progress in clinical and biological research 1991;364():75-80.
1990: Yee-Chun Chen; Pei-Jer Chen; S H Yeh; Hwei-Fang Tien; Chiu-Hwa Wang; Jih-Luh Tang; Ruey-Long Hong
Deletion of the human retinoblastoma gene in primary leukemias.
Blood 1990;76(10):2060-4.
1990: Ping-Ing Lee; Mei-Hwei Chang; C Y Lee; Hong-Yuan Hsu; J S Chen; Pei-Jer Chen; Ding-Shinn Chen
Changes of serum hepatitis B virus DNA and aminotransferase levels during the course of chronic hepatitis B virus infection in children.
Hepatology (Baltimore, Md.) 1990;12(4 Pt 1):657-60.
1990: Ding-Shinn Chen; G C Kuo; J L Sung; Ming-Yang Lai; Jin-Chuan Sheu; Pei-Jer Chen; Pei-Ming Yang; H M Hsu; M H Chang; Chien-Jen Chen
Hepatitis C virus infection in an area hyperendemic for hepatitis B and chronic liver disease: the Taiwan experience.
The Journal of infectious diseases 1990;162(4):817-22.
1990: Ming-Yang Lai; Pei-Jer Chen; P M Yang; J C Sheu; J L Sung; Ding-Shinn Chen
Identification and characterization of intrahepatic hepatitis B virus DNA in HBsAg-seronegative patients with chronic liver disease and hepatocellular carcinoma in Taiwan.
Hepatology (Baltimore, Md.) 1990;12(3 Pt 1):575-81.
1990: Pei-Jer Chen; Mark Yen-Ping Kuo; M L Chen; S J Tu; M N Chiu; Hui-Lin Wu; H C Hsu; Ding-Shinn Chen
Continuous expression and replication of the hepatitis delta virus genome in Hep G2 hepatoblastoma cells transfected with cloned viral DNA.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(14):5253-7.
1989: Pei-Jer Chen; Pei-Ming Yang; C R Chen; Ding-Shinn Chen
Characterization of the transcripts of hepatitis D and B viruses in infected human livers.
The Journal of infectious diseases 1989;160(6):944-7.
1989: Pei-Jer Chen; C R Chen; J L Sung; Ding-Shinn Chen
Identification of a doubly spliced viral transcript joining the separated domains for putative protease and reverse transcriptase of hepatitis B virus.
Journal of virology 1989;63(10):4165-71.
1989: Ho-Hsiung Lin; Pei-Jer Chen; Ding-Shinn Chen; J L Sung; K H Yang; Y C Young; Y S Liou; Y P Chen; TY Lee
Postpartum subsidence of hepatitis B viral replication in HBeAg-positive carrier mothers.
Journal of medical virology 1989;29(1):1-6.
1989: Pei-Jer Chen; Ding-Shinn Chen; Ming-Yang Lai; Mei-Hwei Chang; Guan-Tarn Huang; Pei-Ming Yang; Jin-Chuan Sheu; S C Lee; Hey-Chi Hsu; J L Sung
Clonal origin of recurrent hepatocellular carcinomas.
Gastroenterology 1989;96(2 Pt 1):527-9.
1988: Pei-Jer Chen; Ding-Shinn Chen; C R Chen; Y Y Chen; H M Chen; Ming-Yang Lai; J L Sung
Delta infection in asymptomatic carriers of hepatitis B surface antigen: low prevalence of delta activity and effective suppression of hepatitis B virus replication.
Hepatology (Baltimore, Md.) 1988;8(5):1121-4.
1988: Ming-Yang Lai; Ding-Shinn Chen; Pei-Jer Chen; S C Lee; Jin-Chuan Sheu; Guan-Tarn Huang; T C Wei; C S Lee; S C Yu; H C Hsu
Status of hepatitis B virus DNA in hepatocellular carcinoma: a study based on paired tumor and nontumor liver tissues.
Journal of medical virology 1988;25(3):249-58.