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Tai Chen

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Kun-Chun Chiang; Jun-Te Hsu; Yi-Yin Jan; Horng-Heng Juang; Shyh-Chuan Jwo; Atsushi Kittaka; Masashi Takano; Chun-Te Wu; Chun-Nan Yeh; Ta-Sen Yeh; Huang-Yang Chen; Tai C Chen
Evaluation of the potential therapeutic role of a new generation of vitamin D analog, MART-10, in human pancreatic cancer cells in vitro and in vivo.
Kun-Chun Chiang; Tai C Chen
The Anti-cancer Actions of Vitamin D.
Kaori Yasuda; Masashi Takano; Tai C Chen; Shinichi Ikushiro; Masaki Kamakura; Atsushi Kittaka; Miho Ohta; Nozomi Saito; Toshiyuki Sakaki
Human cytochrome P450-dependent differential metabolism among three 2α-substituted-1α,25-dihydroxyvitamin D(3) analogs.

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All Publications

2013: Kun-Chun Chiang; Jun-Te Hsu; Yi-Yin Jan; Horng-Heng Juang; Shyh-Chuan Jwo; Atsushi Kittaka; Masashi Takano; Chun-Te Wu; Chun-Nan Yeh; Ta-Sen Yeh; Huang-Yang Chen; Tai C Chen
Evaluation of the potential therapeutic role of a new generation of vitamin D analog, MART-10, in human pancreatic cancer cells in vitro and in vivo.
Cell cycle (Georgetown, Tex.) 2013;12(8):1316-25.
2013: Kun-Chun Chiang; Tai C Chen
The Anti-cancer Actions of Vitamin D.
Anti-cancer agents in medicinal chemistry 2013;13(1):126-39.
2013: Kaori Yasuda; Masashi Takano; Tai C Chen; Shinichi Ikushiro; Masaki Kamakura; Atsushi Kittaka; Miho Ohta; Nozomi Saito; Toshiyuki Sakaki
Human cytochrome P450-dependent differential metabolism among three 2α-substituted-1α,25-dihydroxyvitamin D(3) analogs.
The Journal of steroid biochemistry and molecular biology 2013;133():84-92.
2012: Atsushi Kittaka; Toshiyuki Sakaki; Daisuke Sawada; Masashi Takano; Akihiro Yoshida; Kun-Chun Chiang; Tai C Chen
Potent 19-norvitamin D analogs for prostate and liver cancer therapy.
Future medicinal chemistry 2012;4(16):2049-65.
2012: Anne Merewood; Tai C Chen; Xena Grossman; Michael F Holick; Jeff Mathieu; Supriya D Mehta; howard bauchner
Vitamin D status among 4-month-old infants in New England: a prospective cohort study.
Journal of human lactation : official journal of International Lactation Consultant Association 2012;28(2):159-66.
2012: Nirali S Desai; Jennifer K Frediani; Gautam Hebbar; Iagor Kalandadze; Russell R Kempker; Maia Kipiani; Veriko Mirtskhulava; Memorie M Nichols; Ekaterine Sanikidze; Shabnam Seydafkan; Nilay Sutaria; Henry M Blumberg; Tai C Chen; Nestani Tukvadze; Thomas R Ziegler; Vin Tangpricha
Effects of sunlight and diet on vitamin D status of pulmonary tuberculosis patients in Tbilisi, Georgia.
Nutrition (Burbank, Los Angeles County, Calif.) 2012;28(4):362-6.
2012: Kun-Chun Chiang; Jun-Te Hsu; Horng-Heng Juang; Atsushi Kittaka; Jong-Hwei S Pang; Shih-Che Shen; Li-Jen Su; Masashi Takano; Chun-Nan Yeh; Ta-Sen Yeh; Shin-Cheh Chen; Tai C Chen
MART-10, a New Generation of Vitamin D Analog, Is More Potent than 1α,25-Dihydroxyvitamin D(3) in Inhibiting Cell Proliferation and Inducing Apoptosis in ER+ MCF-7 Breast Cancer Cells.
Evidence-based complementary and alternative medicine : eCAM 2012;2012():310872.
2012: Daisuke Sawada; Ken-ichiro Takagi; Kazuya Takenouchi; Yuya Tsukuda; Kaori Yasuda; Tai C Chen; G Satyanarayana Reddy; Hiroshi Saito; Toshiyuki Sakaki; Atsushi Kittaka
Synthesis and biological activities of 1α,4α,25- and 1α,4β,25-trihydroxyvitamin D(3) and their metabolism by human CYP24A1 and UDP-glucuronosyltransferase.
Chemical & pharmaceutical bulletin 2012;60(10):1343-6.
2012: Yasuo Ido; Fan Lan; Lionel Breton; Jose M Cacicedo; Tai C Chen; Albert Duranton; Neil B Ruderman
Acute activation of AMP-activated protein kinase prevents H2O2-induced premature senescence in primary human keratinocytes.
PloS one 2012;7(4):e35092.
2011: Kun-Chun Chiang; Horng-Heng Juang; Atsushi Kittaka; Jim-ming Lee; Masashi Takano; Chun-Nan Yeh; Huang-Yang Chen; Miin-Fu Chen; Tai C Chen
19-Nor-2α-(3-hydroxypropyl)-1α,25-dihydroxyvitamin D3 (MART-10) is a potent cell growth regulator with enhanced chemotherapeutic potency in liver cancer cells.
Steroids 2011;76(13):1513-9.
2011: Rita L Seger; Richard M Seger; Thomas O Carpenter; Robert C Causey; Tai C Chen; Randal A Cross; Caren M Gundberg; William A Halteman; Michael F Holick; Walter J Jakubas; Duane H Keisler; Clifford J Rosen; Frederick A Servello
Investigating the mechanism for maintaining eucalcemia despite immobility and anuria in the hibernating American black bear (Ursus americanus).
Bone 2011;49(6):1205-12.
2011: Diego Iglesias-Gato; Toshimasa Itoh; Lan Jiang; Atsushi Kittaka; Nathan K LeBrasseur; Gunnar Norstedt; Toshiyuki Sakaki; Keiko Yamamoto; Shasha Zheng; John N Flanagan; Tai C Chen
Substitution at carbon 2 of 19-nor-1α,25-dihydroxyvitamin D3 with 3-hydroxypropyl group generates an analogue with enhanced chemotherapeutic potency in PC-3 prostate cancer cells.
The Journal of steroid biochemistry and molecular biology 2011;127(3-5):269-75.
2011: Kun-Chun Chiang; Chun-Nan Yeh; Miin-Fu Chen; Tai C Chen
Hepatocellular carcinoma and vitamin D: a review.
Journal of gastroenterology and hepatology 2011;26(11):1597-603.
2011: Francis A Farraye; R Biancuzzo; A B Boulanger; Tai C Chen; Klea Dendrinos; H Nimitphong; Arthur F Stucchi; A Tanennbaum; A Vijjeswarapu; Michael F Holick
Use of a novel vitamin D bioavailability test demonstrates that vitamin D absorption is decreased in patients with quiescent Crohn's disease.
Inflammatory bowel diseases 2011;17(10):2116-21.
2011: Eiji Munetsuna; Sachie Nakabayashi; Miho Ohta; Midori A Arai; Tai C Chen; Shin-ichi Ikushiro; Masaki Kamakura; Rie Kawanami; Atsushi Kittaka; Kaori Yasuda; Toshiyuki Sakaki
Mechanism of the anti-proliferative action of 25-hydroxy-19-nor-vitamin D(3) in human prostate cells.
Journal of molecular endocrinology 2011;47(2):209-18.
2011: Kumaravel Rajakumar; Michael F Holick; Kwonho Jeong; Charity G Moore; Tai C Chen; Flora Olabopo; Mary Ann Haralam; Anita Nucci; Stephen B Thomas; Susan L Greenspan
Impact of season and diet on vitamin D status of African American and Caucasian children.
Clinical pediatrics 2011;50(6):493-502.
2011: Joseph J Lamb; Michael F Holick; Robert H Lerman; Veera R Konda; Deanna M Minich; Anuradha Desai; Tai C Chen; Melissa Austin; Jacob Kornberg; Jyh-Lurn Chang; Alex Hsi; Jeffrey S Bland; Matthew L Tripp
Nutritional supplementation of hop rho iso-alpha acids, berberine, vitamin D₃, and vitamin K₁ produces a favorable bone biomarker profile supporting healthy bone metabolism in postmenopausal women with metabolic syndrome.
Nutrition research (New York, N.Y.) 2011;31(5):347-55.
2011: Kumaravel Rajakumar; Javier de las Heras; Tai C Chen; SoJung Lee; Michael F Holick; Silva A Arslanian
Vitamin D status, adiposity, and lipids in black American and Caucasian children.
The Journal of clinical endocrinology and metabolism 2011;96(5):1560-7.
2011: Andrzej Slominski; Tae-Kang Kim; Zorica Janjetovic; Robert Tuckey; Radoslaw Bieniek; Junming Yue; Wei Li; Jianjun Chen; Minh N Nguyen; Edith K Y Tang; Duane Miller; Tai C Chen; Michael Holick
20-Hydroxyvitamin D2 is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells.
American journal of physiology. Cell physiology 2011;300(3):C526-41.
2011: Tai C Chen; Atsushi Kittaka
Novel vitamin d analogs for prostate cancer therapy.
ISRN urology 2011;2011():301490.
2010: Debra A Schmidt; Diane Mulkerin; Daniel R Boehm; Mark R Ellersieck; Zhiren Lu; Matthew Campbell; Tai C Chen; Michael F Holick
Quantifying the vitamin D3 synthesizing potential of UVB lamps at specific distances over time.
Zoo biology 2010;29(6):741-52.
2010: Keiko Hayashi; Kaori Yasuda; Hiroshi Sugimoto; Shin-ichi Ikushiro; Masaki Kamakura; Atsushi Kittaka; Ronald L Horst; Tai C Chen; Miho Ohta; Yoshitsugu Shiro; Toshiyuki Sakaki
Three-step hydroxylation of vitamin D3 by a genetically engineered CYP105A1: enzymes and catalysis.
The FEBS journal 2010;277(19):3999-4009.
2010: A Ghosh; N E Joo; Tai C Chen; Yvonne L Kapila
Proapoptotic fibronectin fragment induces the degradation of ubiquitinated p53 via proteasomes in periodontal ligament cells.
Journal of periodontal research 2010;45(4):481-7.
2010: Daphne Carlson-Bremer; Terry M Norton; KV Gilardi; Ellen S Dierenfeld; Brad Winn; Felicia J Sanders; Carolyn Cray; Marcie Oliva; Tai C Chen; Samantha E Gibbs; Maria S Sepúlveda; Christine K Johnson
Health assessment of American Oystercatchers (Haematopus palliatus palliatus) in Georgia and South Carolina.
Journal of wildlife diseases 2010;46(3):772-80.
2010: Yanbin Dong; Norman Pollock; Inger Susanne Stallmann-Jorgensen; Bernard Gutin; Ling Lan; Tai C Chen; Daniel Keeton; Karen Petty; Michael F Holick; Haidong Zhu
Low 25-hydroxyvitamin D levels in adolescents: race, season, adiposity, physical activity, and fitness.
Pediatrics 2010;125(6):1104-11.
2010: Rachael M Biancuzzo; Azzie Young; Douglass Bibuld; Mona H Cai; Michael R Winter; Ellen K Klein; Allen Ameri; Richard Reitz; Wael Salameh; Tai C Chen; Michael F Holick
Fortification of orange juice with vitamin D(2) or vitamin D(3) is as effective as an oral supplement in maintaining vitamin D status in adults.
The American journal of clinical nutrition 2010;91(6):1621-6.
2010: Michael F Holick; Joseph J Lamb; Robert H Lerman; Veera R Konda; Gary Darland; Deanna M Minich; Anuradha Desai; Tai C Chen; Melissa Austin; Jacob Kornberg; Jyh-Lurn Chang; Alex Hsi; Jeffrey S Bland; Matthew L Tripp
Hop rho iso-alpha acids, berberine, vitamin D3 and vitamin K1 favorably impact biomarkers of bone turnover in postmenopausal women in a 14-week trial.
Journal of bone and mineral metabolism 2010;28(3):342-50.
2010: Anne Merewood; Supriya D Mehta; Xena Grossman; Tai C Chen; Jeffrey S Mathieu; Michael F Holick; howard bauchner
Widespread vitamin D deficiency in urban Massachusetts newborns and their mothers.
Pediatrics 2010;125(4):640-7.
2010: Prakash Chandra; sukhdeep basra; Tai C Chen; Vin Tangpricha
Alterations in Lipids and Adipocyte Hormones in Female-to-Male Transsexuals.
International journal of endocrinology 2010;2010():.
2010: Andrzej T Slominski; Zorica Janjetovic; Brian E Fuller; Michal Zmijewski; Robert Tuckey; Minh N Nguyen; Trevor W Sweatman; Wei Li; Jordan K Zjawiony; Duane Miller; Tai C Chen; Gerard Lozanski; Michael F Holick
Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity.
PloS one 2010;5(3):e9907.
2009: Kun-Chun Chiang; Kelly S Persons; Nawfal W Istfan; Michael F Holick; Tai C Chen
Fish oil enhances the antiproliferative effect of 1alpha,25-dihydroxyvitamin D3 on liver cancer cells.
Anticancer research 2009;29(9):3591-6.
2009: Atsushi Kittaka; Hideki Hara; Masashi Takano; Daisuke Sawada; Midori A Arai; Kenichiro Takagi; Takayuki Chida; Yoshifumi Harada; Hiroshi Saito; Kazuya Takenouchi; Seiichi Ishizuka; Keiko Hayashi; Shinichi Ikushiro; Toshiyuki Sakaki; Takayuki Sugiura; Tai C Chen
Synthesis and biological activities of 14-epi-MART-10 and 14-epi-MART-11: implications for cancer and osteoporosis treatment.
Anticancer research 2009;29(9):3563-9.
2009: John N Flanagan; Shasha Zheng; Kun-Chun Chiang; Atsushi Kittaka; Toshiyuki Sakaki; Sachie Nakabayashi; Xiansi Zhao; Remco A Spanjaard; Kelly S Persons; Jeffrey S Mathieu; Michael F Holick; Tai C Chen
Evaluation of 19-nor-2alpha-(3-hydroxypropyl)-1alpha,25-dihydroxyvitamin D3 as a therapeutic agent for androgen-dependent prostate cancer.
Anticancer research 2009;29(9):3547-53.
2009: Carine M Lenders; Henry A Feldman; Emily von Scheven; Anne Merewood; Carol Sweeney; Darrell M Wilson; Phillip D K Lee; Stephanie H Abrams; Stephen E Gitelman; Marcia S Wertz; William J Klish; George A Taylor; Tai C Chen; Michael F Holick
Relation of body fat indexes to vitamin D status and deficiency among obese adolescents.
The American journal of clinical nutrition 2009;90(3):459-67.
2009: Kun-Chun Chiang; Tai C Chen
Vitamin D for the prevention and treatment of pancreatic cancer.
World journal of gastroenterology : WJG 2009;15(27):3349-54.
2009: Michele Miller; Tai C Chen; Michael F Holick; Susan Mikota; Ellen Dierenfeld
Serum concentrations of calcium, phosphorus, and 25-hydroxyvitamin d in captive African elephants (Loxodonta africana).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 2009;40(2):302-5.
2009: Kristopher B Karsten; Gary W Ferguson; Tai C Chen; Michael F Holick
Panther chameleons, Furcifer pardalis, behaviorally regulate optimal exposure to UV depending on dietary vitamin D3 status.
Physiological and biochemical zoology : PBZ 2009;82(3):218-25.
2009: Anne Merewood; Supriya D Mehta; Tai C Chen; Howard Bauchner; Michael F Holick
Association between vitamin D deficiency and primary cesarean section.
The Journal of clinical endocrinology and metabolism 2009;94(3):940-5.
2009: Gordon Klein; David N Herndon; Tai C Chen; Gabriela Kulp; Michael F Holick
Standard multivitamin supplementation does not improve vitamin D insufficiency after burns.
Journal of bone and mineral metabolism 2009;27(4):502-6.
2008: Linda A Linday; Richard D Shindledecker; Jay N Dolitsky; Tai C Chen; Michael F Holick
Plasma 25-hydroxyvitamin D levels in young children undergoing placement of tympanostomy tubes.
The Annals of otology, rhinology, and laryngology 2008;117(10):740-4.
2008: Tai C Chen
25-Hydroxyvitamin D-1 alpha-hydroxylase (CYP27B1) is a new class of tumor suppressor in the prostate.
Anticancer research 2008;28(4A):2015-7.
2008: Lilin Wang; Kelly S Persons; Dan Jamieson; John N Flanagan; Hui H Hsu; Michael F Holick; Zhijun Luo; Toshi Sakaki; N Urushino; Douglas V Faller; Tai C Chen
Prostate 25-hydroxyvitamin D-1alpha-hydroxylase is up-regulated by suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor.
Anticancer research 2008;28(4A):2009-13.
2008: Laura D Carbone; E William Rosenberg; Elizabeth A Tolley; Michael F Holick; Thomas A Hughes; Mitchell A Watsky; Karen D Barrow; Tai C Chen; Nathaniel Wilkin; Syamal K Bhattacharya; John C Dowdy; Robert M Sayre; Karl T Weber
25-Hydroxyvitamin D, cholesterol, and ultraviolet irradiation.
Metabolism: clinical and experimental 2008;57(6):741-8.
2008: Michael F Holick; Tai C Chen
Vitamin D deficiency: a worldwide problem with health consequences.
The American journal of clinical nutrition 2008;87(4):1080S-6S.
2008: Adeboye H Adewoye; Tai C Chen; Qianli Ma; Lillian McMahon; Jeff Mathieu; Alan O Malabanan; Martin H Steinberg; Michael F Holick
Sickle cell bone disease: response to vitamin D and calcium.
American journal of hematology 2008;83(4):271-4.
2008: Michael F Holick; Rachael M Biancuzzo; Tai C Chen; Ellen K Klein; Azzie Young; Douglass Bibuld; Richard Reitz; Wael Salameh; Allen Ameri; Andrew D Tannenbaum
Vitamin D2 is as effective as vitamin D3 in maintaining circulating concentrations of 25-hydroxyvitamin D.
The Journal of clinical endocrinology and metabolism 2008;93(3):677-81.
2008: Marian T Hannan; Heather J Litman; Andre Araujo; Christine E McLennan; Robert R McLean; John B McKinlay; Tai C Chen; Michael F Holick
Serum 25-hydroxyvitamin D and bone mineral density in a racially and ethnically diverse group of men.
The Journal of clinical endocrinology and metabolism 2008;93(1):40-6.
2007: Michael F Holick; Tai C Chen; Zhiren Lu; Edward Sauter
Vitamin D and skin physiology: a D-lightful story.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007;22 Suppl 2():V28-33.
2007: Prakash Chandra; Linda L Wolfenden; Thomas R Ziegler; Junqiang Tian; Menghua Luo; Arlene A Stecenko; Tai C Chen; Michael F Holick; Vin Tangpricha
Treatment of vitamin D deficiency with UV light in patients with malabsorption syndromes: a case series.
Photodermatology, photoimmunology & photomedicine 2007;23(5):179-85.
2007: Naoko Urushino; Sachie Nakabayashi; Midori A Arai; Atsushi Kittaka; Tai C Chen; Keiko Yamamoto; Keiko Hayashi; Shigeaki Kato; Miho Ohta; Masaki Kamakura; Shin-ichi Ikushiro; Toshiyuki Sakaki
Kinetic studies of 25-hydroxy-19-nor-vitamin D3 and 1 alpha,25-dihydroxy-19-nor-vitamin D3 hydroxylation by CYP27B1 and CYP24A1.
Drug metabolism and disposition: the biological fate of chemicals 2007;35(9):1482-8.
2007: Midori A Arai; Ken-ichi Takeyama; Saya Ito; Shigeaki Kato; Tai C Chen; Atsushi Kittaka
High-throughput system for analyzing ligand-induced cofactor recruitment by vitamin D receptor.
Bioconjugate chemistry 2007;18(3):614-20.
2007: Tai C Chen; Farhad Chimeh; Zhiren Lu; Jeffrey Mathieu; Kelly S Person; Anqi Zhang; Nathan Kohn; Stephen Martinello; Roger Berkowitz; Michael F Holick
Factors that influence the cutaneous synthesis and dietary sources of vitamin D.
Archives of biochemistry and biophysics 2007;460(2):213-7.
2007: Zhiren Lu; Tai C Chen; A Zhang; Kelly S Persons; N Kohn; R Berkowitz; S Martinello; Michael F Holick
An evaluation of the vitamin D3 content in fish: Is the vitamin D content adequate to satisfy the dietary requirement for vitamin D?
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):642-4.
2007: Atsushi Kittaka; Nozomi Saito; Shinobu Honzawa; Kazuya Takenouchi; Seiichi Ishizuka; Tai C Chen; Sara Peleg; Shigeaki Kato; Midori A Arai
Creative synthesis of novel vitamin D analogs for health and disease.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):269-76.
2007: Nawfal W Istfan; K S Person; Michael F Holick; Tai C Chen
1alpha,25-Dihydroxyvitamin D and fish oil synergistically inhibit G1/S-phase transition in prostate cancer cells.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):726-30.
2007: Tai C Chen; Kelly S Persons; S Zheng; J Mathieu; Michael F Holick; Y F Lee; B Bao; M A Arai; Atsushi Kittaka
Evaluation of C-2-substituted 19-nor-1alpha,25-dihydroxyvitamin D3 analogs as therapeutic agents for prostate cancer.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):717-20.
2007: Kerry E Broe; Tai C Chen; Janice Weinberg; Heike A Bischoff-Ferrari; Michael F Holick; Douglas P Kiel
A higher dose of vitamin d reduces the risk of falls in nursing home residents: a randomized, multiple-dose study.
Journal of the American Geriatrics Society 2007;55(2):234-9.
2007: Joyce M Lee; Jessica R Smith; Barbara L Philipp; Tai C Chen; Jeffrey Mathieu; Michael F Holick
Vitamin D deficiency in a healthy group of mothers and newborn infants.
Clinical pediatrics 2007;46(1):42-4.
2006: Michael Friedrich; Dagmar Diesing; Tim Cordes; Dorothea Fischer; Stefanie Becker; Tai C Chen; John N Flanagan; Vin Tangpricha; Ingrid Gherson; Michael F Holick; Jörg Reichrath
Analysis of 25-hydroxyvitamin D3-1alpha-hydroxylase in normal and malignant breast tissue.
Anticancer research 2006;26(4A):2615-20.
2006: John N Flanagan; Michael V Young; Kelly S Persons; Lilin Wang; Jeffrey S Mathieu; Lyman W Whitlatch; Michael F Holick; Tai C Chen
Vitamin D metabolism in human prostate cells: implications for prostate cancer chemoprevention by vitamin D.
Anticancer research 2006;26(4A):2567-72.
2006: Leonid M Shinchuk; Leslie Morse; Nadia Huancahuari; Seth M Arum; Tai C Chen; Michael F Holick
Vitamin D deficiency and osteoporosis in rehabilitation inpatients.
Archives of physical medicine and rehabilitation 2006;87(7):904-8.
2005: Vin Tangpricha; Catherine Spina; Min Yao; Tai C Chen; M Michael Wolfe; Michael F Holick
Vitamin D deficiency enhances the growth of MC-26 colon cancer xenografts in Balb/c mice.
The Journal of nutrition 2005;135(10):2350-4.
2005: Jan C Ramer; Roberto Maria; Tim Reichard; Peter J Tolson; Tai C Chen; Michael F Holick
Vitamin D status of wild Ricord's iguanas (Cyclura ricordii) and captive and wild rhinoceros iguanas (Cyclura cornuta cornuta) in the Dominican Republic.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 2005;36(2):188-91.
2005: Susan S Sullivan; Clifford J Rosen; William A Halteman; Tai C Chen; Michael F Holick
Adolescent girls in Maine are at risk for vitamin D insufficiency.
Journal of the American Dietetic Association 2005;105(6):971-4.
2005: Gary W Ferguson; William H Gehrmann; Kristopher B Karsten; Allan J Landwer; Elliott N Carman; Tai C Chen; Michael F Holick
Ultraviolet exposure and vitamin D synthesis in a sun-dwelling and a shade-dwelling species of Anolis: are there adaptations for lower ultraviolet B and dietary vitamin D3 availability in the shade?
Physiological and biochemical zoology : PBZ 2005;78(2):193-200.
2004: Vin Tangpricha; Adrian Turner; Catherine Spina; Sheila Decastro; Tai C Chen; Michael F Holick
Tanning is associated with optimal vitamin D status (serum 25-hydroxyvitamin D concentration) and higher bone mineral density.
The American journal of clinical nutrition 2004;80(6):1645-9.
2004: Narasimha Swamy; Tai C Chen; Sara Peleg; Puneet Dhawan; Sylvia Christakos; LaMonica V Stewart; Nancy L Weigel; Rajendra Mehta; Michael F Holick; Rahul Ray
Inhibition of proliferation and induction of apoptosis by 25-hydroxyvitamin D3-3beta-(2)-Bromoacetate, a nontoxic and vitamin D receptor-alkylating analog of 25-hydroxyvitamin D3 in prostate cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(23):8018-27.
2004: Adrian Turner; Tai C Chen; Thomas W Barber; Alan O Malabanan; Michael F Holick; Vin Tangpricha
Testosterone increases bone mineral density in female-to-male transsexuals: a case series of 15 subjects.
Clinical endocrinology 2004;61(5):560-6.
2004: Gary G Schwartz; Dawn Eads; Anuradha Rao; Scott D Cramer; Mark C Willingham; Tai C Chen; Daniel P Jamieson; Lilin Wang; Kerry L Burnstein; Michael F Holick; Constantinos Koumenis
Pancreatic cancer cells express 25-hydroxyvitamin D-1 alpha-hydroxylase and their proliferation is inhibited by the prohormone 25-hydroxyvitamin D3.
Carcinogenesis 2004;25(6):1015-26.
2004: Michael V Young; Gary G Schwartz; Lilin Wang; Daniel P Jamieson; Lyman W Whitlatch; John N Flanagan; Bal Lokeshwar; Michael F Holick; Tai C Chen
The prostate 25-hydroxyvitamin D-1 alpha-hydroxylase is not influenced by parathyroid hormone and calcium: implications for prostate cancer chemoprevention by vitamin D.
Carcinogenesis 2004;25(6):967-71.
2004: Vin Tangpricha; Natalia A Colon; Heema Kaul; Shirley L Wang; Sheila Decastro; Rita A Blanchard; Tai C Chen; Michael F Holick
Prevalence of vitamin D deficiency in patients attending an outpatient cancer care clinic in Boston.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2004;10(3):292-3.
2004: Lilin Wang; John N Flanagan; Lyman W Whitlatch; Daniel P Jamieson; Michael F Holick; Tai C Chen
Regulation of 25-hydroxyvitamin D-1alpha-hydroxylase by epidermal growth factor in prostate cells.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):127-30.
2004: Gordon Klein; Tai C Chen; Michael F Holick; Craig B Langman; Heather Price; Mario M Celis; David N Herndon
Synthesis of vitamin D in skin after burns.
Lancet 2004;363(9405):291-2.
2003: Tai C Chen; Michael F Holick
Vitamin D and prostate cancer prevention and treatment.
Trends in endocrinology and metabolism: TEM 2003;14(9):423-30.
2003: Narasimha Swamy; Kelly S Persons; Tai C Chen; Rahul Ray
1alpha,25-Dihydroxyvitamin D3-3beta-(2)-bromoacetate, an affinity labeling derivative of 1alpha,25-dihydroxyvitamin D3 displays strong antiproliferative and cytotoxic behavior in prostate cancer cells.
Journal of cellular biochemistry 2003;89(5):909-16.
2003: Vin Tangpricha; Polyxeni Koutkia; Suzanne M Rieke; Tai C Chen; Alberto A Perez; Michael F Holick
Fortification of orange juice with vitamin D: a novel approach for enhancing vitamin D nutritional health.
The American journal of clinical nutrition 2003;77(6):1478-83.
2003: Joshua Safer; Tara M Crawford; Lisa M Fraser; Michael Hoa; Swapna Ray; Tai C Chen; Kelly S Persons; Michael F Holick
Thyroid hormone action on skin: diverging effects of topical versus intraperitoneal administration.
Thyroid : official journal of the American Thyroid Association 2003;13(2):159-65.
2003: Tai C Chen; Lilin Wang; Lyman W Whitlatch; John N Flanagan; Michael F Holick
Prostatic 25-hydroxyvitamin D-1alpha-hydroxylase and its implication in prostate cancer.
Journal of cellular biochemistry 2003;88(2):315-22.
2003: Tai C Chen; Michael F Holick; Bal Lokeshwar; Kerry L Burnstein; Gary G Schwartz
Evaluation of vitamin D analogs as therapeutic agents for prostate cancer.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2003;164():273-88.
2003: Lilin Wang; Lyman W Whitlatch; John N Flanagan; Michael F Holick; Tai C Chen
Vitamin D autocrine system and prostate cancer.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2003;164():223-37.
2003: John N Flanagan; Lilin Wang; Vin Tangpricha; Jörg Reichrath; Tai C Chen; Michael F Holick
Regulation of the 25-hydroxyvitamin D-1alpha-hydroxylase gene and its splice variant.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2003;164():157-67.
2003: Gary W Ferguson; William H Gehrmann; Kristopher B Karsten; Stephen H Hammack; Michele McRae; Tai C Chen; Nancy P Lung; Michael F Holick
Do panther chameleons bask to regulate endogenous vitamin D3 production?
Physiological and biochemical zoology : PBZ 2003;76(1):52-9.
2003: Robert P Heaney; K Michael Davies; Tai C Chen; Michael F Holick; M Janet Barger-Lux
Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol.
The American journal of clinical nutrition 2003;77(1):204-10.
2002: Lyman W Whitlatch; Michael V Young; Gary G Schwartz; John N Flanagan; Kerry L Burnstein; Bal Lokeshwar; Edwin S Rich; Michael F Holick; Tai C Chen
25-Hydroxyvitamin D-1alpha-hydroxylase activity is diminished in human prostate cancer cells and is enhanced by gene transfer.
The Journal of steroid biochemistry and molecular biology 2002;81(2):135-40.
2002: Vin Tangpricha; Elizabeth N Pearce; Tai C Chen; Michael F Holick
Vitamin D insufficiency among free-living healthy young adults.
The American journal of medicine 2002;112(8):659-62.
2002: Marcus Clauss; David A Jessup; Edward B Norkus; Tai C Chen; Michael F Holick; Wolf Jürgen Streich; Ellen S Dierenfeld
Fat soluble vitamins in blood and tissues of free-ranging and captive rhinoceros.
Journal of wildlife diseases 2002;38(2):402-13.
2002: Ursula Bechert; Jack Mortenson; Ellen S Dierenfeld; Peter Cheeke; Mark Keller; Michael Holick; Tai C Chen; Quinton Rogers
Diet composition and blood values of captive cheetahs (Acinonyx jubatus) fed either supplemented meat or commercial food preparations.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 2002;33(1):16-28.
2001: Polyxeni Koutkia; Zhiren Lu; Tai C Chen; Michael F Holick
Treatment of vitamin D deficiency due to Crohn's disease with tanning bed ultraviolet B radiation.
Gastroenterology 2001;121(6):1485-8.
2001: John N Flanagan; Lyman W Whitlatch; Tai C Chen; X H Zhu; M T Holick; X F Kong; Michael F Holick
Enhancing 1 alpha-hydroxylase activity with the 25-hydroxyvitamin D-1 alpha-hydroxylase gene in cultured human keratinocytes and mouse skin.
The Journal of investigative dermatology 2001;116(6):910-4.
2001: Vin Tangpricha; John N Flanagan; Lyman W Whitlatch; C C Tseng; Tai C Chen; P R Holt; Martin Lipkin; Michael F Holick
25-hydroxyvitamin D-1alpha-hydroxylase in normal and malignant colon tissue.
Lancet 2001;357(9269):1673-4.
2000: Tai C Chen; Kelly S Persons; Zhiren Lu; J S Mathieu; Michael F Holick
An evaluation of the biologic activity and vitamin D receptor binding affinity of the photoisomers of vitamin D3 and previtamin D3.
The Journal of nutritional biochemistry 2000;11(5):267-72.
2000: E T Obi-Tabot; X Q Tian; Tai C Chen; Michael F Holick
A human skin equivalent model that mimics the photoproduction of vitamin D3 in human skin.
In vitro cellular & developmental biology. Animal 2000;36(3):201-4.
2000: Tai C Chen; Gary G Schwartz; Kerry L Burnstein; Bal Lokeshwar; Michael F Holick
The in vitro evaluation of 25-hydroxyvitamin D3 and 19-nor-1alpha,25-dihydroxyvitamin D2 as therapeutic agents for prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(3):901-8.
1998: Gary G Schwartz; Lyman W Whitlatch; Tai C Chen; Bal Lokeshwar; Michael F Holick
Human prostate cells synthesize 1,25-dihydroxyvitamin D3 from 25-hydroxyvitamin D3.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1998;7(5):391-5.
1998: M Janet Barger-Lux; Robert P Heaney; S Dowell; Tai C Chen; Michael F Holick
Vitamin D and its major metabolites: serum levels after graded oral dosing in healthy men.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 1998;8(3):222-30.
1997: Robert P Heaney; M Janet Barger-Lux; M Susan Dowell; Tai C Chen; Michael F Holick
Calcium absorptive effects of vitamin D and its major metabolites.
The Journal of clinical endocrinology and metabolism 1997;82(12):4111-6.