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John Alderete

Research Profile

Chemicals & Drugs

Physiology

Cell Adhesion

Anatomy

Disorders

Trichomonas Vaginitis

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Molecular Sequence Data

Genes & Molecular Sequences

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Publications

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Jennifer R Stark; Gregory Judson; John F Alderete; Vasanthakrishna Mundodi; Ashwini S Kucknoor; Edward L Giovannucci; Elizabeth A Platz; Siobhan Sutcliffe; Katja Fall; Tobias Kurth; Jing Ma; Meir J Stampfer; Lorelei A Mucci
Prospective study of Trichomonas vaginalis infection and prostate cancer incidence and mortality: Physicians' Health Study.
A Lama; Ashwini S Kucknoor; Vasanthakrishna Mundodi; John F Alderete
Glyceraldehyde-3-phosphate dehydrogenase is a surface-associated, fibronectin-binding protein of Trichomonas vaginalis.
Ashwini S Kucknoor; Vasanthakrishna Mundodi; John F Alderete
Genetic identity and differential gene expression between Trichomonas vaginalis and Trichomonas tenax.

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All Publications

2009: Jennifer R Stark; Gregory Judson; John F Alderete; Vasanthakrishna Mundodi; Ashwini S Kucknoor; Edward L Giovannucci; Elizabeth A Platz; Siobhan Sutcliffe; Katja Fall; Tobias Kurth; Jing Ma; Meir J Stampfer; Lorelei A Mucci
Prospective study of Trichomonas vaginalis infection and prostate cancer incidence and mortality: Physicians' Health Study.
Journal of the National Cancer Institute 2009;101(20):1406-11.
2009: A Lama; Ashwini S Kucknoor; Vasanthakrishna Mundodi; John F Alderete
Glyceraldehyde-3-phosphate dehydrogenase is a surface-associated, fibronectin-binding protein of Trichomonas vaginalis.
Infection and immunity 2009;77(7):2703-11.
2009: Ashwini S Kucknoor; Vasanthakrishna Mundodi; John F Alderete
Genetic identity and differential gene expression between Trichomonas vaginalis and Trichomonas tenax.
BMC microbiology 2009;9():58.
2008: Vasanthakrishna Mundodi; Ashwini S Kucknoor; John F Alderete
Immunogenic and plasminogen-binding surface-associated alpha-enolase of Trichomonas vaginalis.
Infection and immunity 2008;76(2):523-31.
2008: Muriel Mazet; Marie Diogon; John F Alderete; Christian P Vivarès; Frédéric Delbac
First molecular characterisation of hydrogenosomes in the protozoan parasite Histomonas meleagridis.
International journal for parasitology 2008;38(2):177-90.
2008: María Elizbeth Alvarez-Sánchez; Bertha Isabel Carvajal-Gamez; Eduardo Solano-González; Máximo Martínez-Benitez; Ana F Garcia; John F Alderete; Rossana Arroyo
Polyamine depletion down-regulates expression of the Trichomonas vaginalis cytotoxic CP65, a 65-kDa cysteine proteinase involved in cellular damage.
The international journal of biochemistry & cell biology 2008;40(11):2442-51.
2007: Ashwini S Kucknoor; Vasanthakrishna Mundodi; John F Alderete
The proteins secreted by Trichomonas vaginalis and vaginal epithelial cell response to secreted and episomally expressed AP65.
Cellular microbiology 2007;9(11):2586-97.
2007: Ana F Garcia; John F Alderete
Characterization of the Trichomonas vaginalis surface-associated AP65 and binding domain interacting with trichomonads and host cells.
BMC microbiology 2007;7():116.
2007: Vasanthakrishna Mundodi; Ashwini S Kucknoor; John F Alderete
Antisense RNA decreases AP33 gene expression and cytoadherence by T. vaginalis.
BMC microbiology 2007;7():64.
2006: Siobhan Sutcliffe; Edward Giovannucci; John F Alderete; Te-Hung Chang; Charlotte A Gaydos; Jonathan M Zenilman; Angelo M DeMarzo; Walter C Willett; Elizabeth A Platz
Plasma antibodies against Trichomonas vaginalis and subsequent risk of prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(5):939-45.
2006: Vasanthakrishna Mundodi; Ashwini S Kucknoor; Te-Hung Chang; John F Alderete
A novel surface protein of Trichomonas vaginalis is regulated independently by low iron and contact with vaginal epithelial cells.
BMC microbiology 2006;6():6.
2005: Ashwini S Kucknoor; Vasanthakrishna Mundodi; John F Alderete
Adherence to human vaginal epithelial cells signals for increased expression of Trichomonas vaginalis genes.
Infection and immunity 2005;73(10):6472-8.
2005: Rodrigo Furtado Madeiro da Costa; Wanderley de Souza; Marlene Benchimol; John F Alderete; Jose Andres Morgado-Diaz
Trichomonas vaginalis perturbs the junctional complex in epithelial cells.
Cell research 2005;15(9):704-16.
2005: Ashwini S Kucknoor; Vasanthakrishna Mundodi; John F Alderete
Trichomonas vaginalis adherence mediates differential gene expression in human vaginal epithelial cells.
Cellular microbiology 2005;7(6):887-97.
2005: Ana F Garcia; Marlene Benchimol; John F Alderete
Trichomonas vaginalis polyamine metabolism is linked to host cell adherence and cytotoxicity.
Infection and immunity 2005;73(5):2602-10.
2005: Ashwini S Kucknoor; Vasanthakrishna Mundodi; John F Alderete
Heterologous expression in Tritrichomonas foetus of functional Trichomonas vaginalis AP65 adhesin.
BMC molecular biology 2005;6():5.
2004: Vasanthakrishna Mundodi; Ashwini S Kucknoor; D J Klumpp; Te-Hung Chang; John F Alderete
Silencing the ap65 gene reduces adherence to vaginal epithelial cells by Trichomonas vaginalis.
Molecular microbiology 2004;53(4):1099-108.
2004: John F Alderete; J Nguyen; Vasanthakrishna Mundodi; Michael W Lehker
Heme-iron increases levels of AP65-mediated adherence by Trichomonas vaginalis.
Microbial pathogenesis 2004;36(5):263-71.
2003: Ana F Garcia; Te-Hung Chang; Marlene Benchimol; David Jichael Klumpp; Michael W Lehker; John F Alderete
Iron and contact with host cells induce expression of adhesins on surface of Trichomonas vaginalis.
Molecular microbiology 2003;47(5):1207-24.
2003: John F Alderete; Karen A Wendel; Anne M Rompalo; Emily J Erbelding; Marlene Benchimol; Te-Hung Chang
Trichomonas vaginalis: evaluating capsid proteins of dsRNA viruses and the dsRNA virus within patients attending a sexually transmitted disease clinic.
Experimental parasitology 2003;103(1-2):44-50.
2002: Marlene Benchimol; TH Chang; John F Alderete
Visualization of new virus-like-particles in Trichomonas vaginalis.
Tissue & cell 2002;34(6):406-15.
2002: Marlene Benchimol; TH Chang; John F Alderete
Trichomonas vaginalis: observation of coexistence of multiple viruses in the same isolate.
FEMS microbiology letters 2002;215(2):197-201.
2002: Marlene Benchimol; Sandra Monteiro; TH Chang; John F Alderete
Virus in Trichomonas--an ultrastructural study.
Parasitology international 2002;51(3):293-8.
2002: John F Alderete; Marlene Benchimol; Michael W Lehker; ML Crouch
The complex fibronectin--Trichomonas vaginalis interactions and Trichomonosis.
Parasitology international 2002;51(3):285-92.
2002: Karen A Wendel; Anne M Rompalo; Emily J Erbelding; Te-Hung Chang; John F Alderete
Double-stranded RNA viral infection of Trichomonas vaginalis infecting patients attending a sexually transmitted diseases clinic.
The Journal of infectious diseases 2002;186(4):558-61.
2001: Marlene Benchimol; Karla Consort Ribeiro; Rafael Meyer Mariante; John F Alderete
Structure and division of the Golgi complex in Trichomonas vaginalis and Tritrichomonas foetus.
European journal of cell biology 2001;80(9):593-607.
2001: ML Crouch; Marlene Benchimol; John F Alderete
Binding of fibronectin by Trichomonas vaginalis is influenced by iron and calcium.
Microbial pathogenesis 2001;31(3):131-44.
2001: John F Alderete; K W Millsap; Michael W Lehker; Marlene Benchimol
Enzymes on microbial pathogens and Trichomonas vaginalis: molecular mimicry and functional diversity.
Cellular microbiology 2001;3(6):359-70.
2001: M V Crouch; John F Alderete
Trichomonas vaginalis has two fibronectin-like iron-regulated genes.
Archives of medical research 2001;32(2):102-7.
1999: Michael W Lehker; John F Alderete
Resolution of six chromosomes of Trichomonas vaginalis and conservation of size and number among isolates.
The Journal of parasitology 1999;85(5):976-9.
1999: ML Crouch; John F Alderete
Trichomonas vaginalis interactions with fibronectin and laminin.
Microbiology (Reading, England) 1999;145 ( Pt 10)():2835-43.
1999: Oxana Musatovova; John F Alderete
The Trichomonas vaginalis phenotypically varying P270 immunogen is highly conserved except for numbers of repeated elements.
Microbial pathogenesis 1999;27(2):93-104.
1999: John F Alderete
Iron modulates phenotypic variation and phosphorylation of P270 in double-stranded RNA virus-infected Trichomonas vaginalis.
Infection and immunity 1999;67(8):4298-302.
1998: JA Engbring; John F Alderete
Characterization of Trichomonas vaginalis AP33 adhesin and cell surface interactive domains.
Microbiology (Reading, England) 1998;144 ( Pt 11)():3011-8.
1998: JA Engbring; John F Alderete
Three genes encode distinct AP33 proteins involved in Trichomonas vaginalis cytoadherence.
Molecular microbiology 1998;28(2):305-13.
1998: Oxana Musatovova; John F Alderete
Molecular analysis of the gene encoding the immunodominant phenotypically varying P270 protein of Trichomonas vaginalis.
Microbial pathogenesis 1998;24(4):223-39.
1998: John F Alderete; JA Engbring; C M Lauriano; J L O'Brien
Only two of the Trichomonas vaginalis triplet AP51 adhesins are regulated by iron.
Microbial pathogenesis 1998;24(1):1-16.
1997: John F Alderete; Daniele Provenzano
The vagina has reducing environment sufficient for activation of Trichomonas vaginalis cysteine proteinases.
Genitourinary medicine 1997;73(4):291-6.
1997: Daniele Provenzano; A Khoshnan; John F Alderete
Involvement of dsRNA virus in the protein composition and growth kinetics of host Trichomonas vaginalis.
Archives of virology 1997;142(5):939-52.
1996: J L O'Brien; C M Lauriano; John F Alderete
Molecular characterization of a third malic enzyme-like AP65 adhesin gene of Trichomonas vaginalis.
Microbial pathogenesis 1996;20(6):335-49.
1996: J A Engbring; J L O'Brien; John F Alderete
Trichomonas vaginalis adhesin proteins display molecular mimicry to metabolic enzymes.
Advances in experimental medicine and biology 1996;408():207-23.
1995: A Khoshnan; John F Alderete
Characterization of double-stranded RNA satellites associated with the Trichomonas vaginalis virus.
Journal of virology 1995;69(11):6892-7.
1995: Daniele Provenzano; John F Alderete
Analysis of human immunoglobulin-degrading cysteine proteinases of Trichomonas vaginalis.
Infection and immunity 1995;63(9):3388-95.
1995: John F Alderete; Daniele Provenzano; Michael W Lehker
Iron mediates Trichomonas vaginalis resistance to complement lysis.
Microbial pathogenesis 1995;19(2):93-103.
1995: John F Alderete; J L O'Brien; Rossana Arroyo; J A Engbring; Oxana Musatovova; O Lopez; C Lauriano; J Nguyen
Cloning and molecular characterization of two genes encoding adhesion proteins involved in Trichomonas vaginalis cytoadherence.
Molecular microbiology 1995;17(1):69-83.
1995: Rossana Arroyo; John F Alderete
Two Trichomonas vaginalis surface proteinases bind to host epithelial cells and are related to levels of cytoadherence and cytotoxicity.
Archives of medical research 1995;26(3):279-85.
1995: Rossana Arroyo; J Engbring; J Nguyen; Oxana Musatovova; O López; C Lauriano; John F Alderete
Characterization of cDNAs encoding adhesin proteins involved in trichomonas vaginalis cytoadherence.
Archives of medical research 1995;26(4):361-9.
1995: John F Alderete; Rossana Arroyo; Michael W Lehker
Analysis for adhesins and specific cytoadhesion of Trichomonas vaginalis.
Methods in enzymology 1995;253():407-14.
1994: A Khoshnan; Daniele Provenzano; John F Alderete
Unique double-stranded RNAs associated with the Trichomonas vaginalis virus are synthesized by viral RNA-dependent RNA polymerase.
Journal of virology 1994;68(11):7108-14.
1994: A Khoshnan; John F Alderete
Trichomonas vaginalis with a double-stranded RNA virus has upregulated levels of phenotypically variable immunogen mRNA.
Journal of virology 1994;68(6):4035-8.
1994: John F Alderete; Rossana Arroyo; Michael W Lehker
Identification of fibronectin as a receptor for bacterial cytoadherence.
Methods in enzymology 1994;236():318-33.
1993: A Khoshnan; John F Alderete
Multiple double-stranded RNA segments are associated with virus particles infecting Trichomonas vaginalis.
Journal of virology 1993;67(12):6950-5.
1993: Rossana Arroyo; Arturo González-Robles; Adolfo Martínez-Palomo; John F Alderete
Signalling of Trichomonas vaginalis for amoeboid transformation and adhesion synthesis follows cytoadherence.
Molecular microbiology 1993;7(2):299-309.
1992: P Bózner; A Gombosová; M Valent; P Demes; John F Alderete
Proteinases of Trichomonas vaginalis: antibody response in patients with urogenital trichomoniasis.
Parasitology 1992;105 ( Pt 3)():387-91.
1992: Rossana Arroyo; J Engbring; John F Alderete
Molecular basis of host epithelial cell recognition by Trichomonas vaginalis.
Molecular microbiology 1992;6(7):853-62.
1992: John F Alderete; Rossana Arroyo; D C Dailey; J Engbring; M A Khoshnan; Michael W Lehker; J McKay
Molecular analysis of Trichomonas vaginalis surface protein repertoires.
Molecular and cell biology of human diseases series 1992;1():173-202.
1992: Michael W Lehker; John F Alderete
Iron regulates growth of Trichomonas vaginalis and the expression of immunogenic trichomonad proteins.
Molecular microbiology 1992;6(1):123-32.
1991: John F Alderete; E Newton; C Dennis; K A Neale
The vagina of women infected with Trichomonas vaginalis has numerous proteinases and antibody to trichomonad proteinases.
Genitourinary medicine 1991;67(6):469-74.
1991: John F Alderete; E Newton; C Dennis; K A Neale
Antibody in sera of patients infected with Trichomonas vaginalis is to trichomonad proteinases.
Genitourinary medicine 1991;67(4):331-4.
1991: Michael W Lehker; Rossana Arroyo; John F Alderete
The regulation by iron of the synthesis of adhesins and cytoadherence levels in the protozoan Trichomonas vaginalis.
The Journal of experimental medicine 1991;174(2):311-8.
1991: John F Alderete; E Newton; C Dennis; J Engbring; K A Neale
Vaginal antibody of patients with trichomoniasis is to a prominent surface immunogen of Trichomonas vaginalis.
Genitourinary medicine 1991;67(3):220-5.
1991: D C Dailey; John F Alderete
The phenotypically variable surface protein of Trichomonas vaginalis has a single, tandemly repeated immunodominant epitope.
Infection and immunity 1991;59(6):2083-8.
1990: D C Dailey; T H Chang; John F Alderete
Characterization of Trichomonas vaginalis haemolysis.
Parasitology 1990;101 Pt 2():171-5.
1990: Michael W Lehker; John F Alderete
Properties of Trichomonas vaginalis grown under chemostat controlled growth conditions.
Genitourinary medicine 1990;66(3):193-9.
1990: Michael W Lehker; T H Chang; D C Dailey; John F Alderete
Specific erythrocyte binding is an additional nutrient acquisition system for Trichomonas vaginalis.
The Journal of experimental medicine 1990;171(6):2165-70.
1990: K A Neale; John F Alderete
Analysis of the proteinases of representative Trichomonas vaginalis isolates.
Infection and immunity 1990;58(1):157-62.
1989: Rossana Arroyo; John F Alderete
Trichomonas vaginalis surface proteinase activity is necessary for parasite adherence to epithelial cells.
Infection and immunity 1989;57(10):2991-7.
1989: John F Alderete; K A Neale
Relatedness of structures of a major immunogen in Trichomonas vaginalis isolates.
Infection and immunity 1989;57(6):1849-53.
1989: John F Alderete; Joel Baseman
Serum lipoprotein binding by Treponema pallidum: possible role for proteoglycans.
Genitourinary medicine 1989;65(3):177-82.
1988: John F Alderete; K M Peterson; Joel Baseman
Affinities of Treponema pallidum for human lactoferrin and transferrin.
Genitourinary medicine 1988;64(6):359-63.
1988: John F Alderete; P Demeś; A Gombosova; M Valent; M Fabusová; A Jánoska; J Stefanovic; Rossana Arroyo
Specific parasitism of purified vaginal epithelial cells by Trichomonas vaginalis.
Infection and immunity 1988;56(10):2558-62.
1988: John F Alderete
Alternating phenotypic expression of two classes of Trichomonas vaginalis surface markers.
Reviews of infectious diseases 1988;10 Suppl 2():S408-12.
1988: John F Alderete
Does lactobacillus vaccine for trichomoniasis, Solco Trichovac, induce antibody reactive with Trichomonas vaginalis?
Genitourinary medicine 1988;64(2):118-23.
1988: John F Alderete; G E Garza
Identification and properties of Trichomonas vaginalis proteins involved in cytadherence.
Infection and immunity 1988;56(1):28-33.
1987: K Peterson; Joel Baseman; John F Alderete
Molecular cloning of Treponema pallidum outer envelope fibronectin binding proteins, P1 and P2.
Genitourinary medicine 1987;63(6):355-60.
1987: K M Peterson; Joel Baseman; John F Alderete
Cloning structural genes for Treponema pallidum immunogens and characterisation of recombinant treponemal surface protein, P2 (P2 star).
Genitourinary medicine 1987;63(5):289-96.
1987: John F Alderete; P Demĕs; A Gombosová; M Valent; A Yánoska; H Fabusová; L Kasmala; G E Garza; E C Metcalfe
Phenotypes and protein-epitope phenotypic variation among fresh isolates of Trichomonas vaginalis.
Infection and immunity 1987;55(5):1037-41.
1986: K M Peterson; Joel Baseman; John F Alderete
Isolation of a Treponema pallidum gene encoding immunodominant outer envelope protein P6, which reacts with sera from patients at different stages of syphilis.
The Journal of experimental medicine 1986;164(4):1160-70.
1986: John F Alderete; L Kasmala
Monoclonal antibody to a major glycoprotein immunogen mediates differential complement-independent lysis of Trichomonas vaginalis.
Infection and immunity 1986;53(3):697-9.
1986: John F Alderete; L Kasmala; E Metcalfe; G E Garza
Phenotypic variation and diversity among Trichomonas vaginalis isolates and correlation of phenotype with trichomonal virulence determinants.
Infection and immunity 1986;53(2):285-93.
1986: John F Alderete; L Suprun-Brown; L Kasmala
Monoclonal antibody to a major surface glycoprotein immunogen differentiates isolates and subpopulations of Trichomonas vaginalis.
Infection and immunity 1986;52(1):70-5.
1986: John F Alderete; G Garza; J Smith; M Spence
Trichomonas vaginalis: electrophoretic analysis and heterogeneity among isolates due to high-molecular-weight trichomonad proteins.
Experimental parasitology 1986;61(2):244-51.
1985: John F Alderete; G E Garza
Specific nature of Trichomonas vaginalis parasitism of host cell surfaces.
Infection and immunity 1985;50(3):701-8.
1985: John F Alderete; L Suprun-Brown; L Kasmala; J Smith; M Spence
Heterogeneity of Trichomonas vaginalis and discrimination among trichomonal isolates and subpopulations with sera of patients and experimentally infected mice.
Infection and immunity 1985;49(3):463-8.
1984: K M Peterson; John F Alderete
Trichomonas vaginalis is dependent on uptake and degradation of human low density lipoproteins.
The Journal of experimental medicine 1984;160(5):1261-72.
1984: John F Alderete; G E Garza
Soluble Trichomonas vaginalis antigens in cell-free culture supernatants.
Molecular and biochemical parasitology 1984;13(2):147-58.
1984: K M Peterson; John F Alderete
Iron uptake and increased intracellular enzyme activity follow host lactoferrin binding by Trichomonas vaginalis receptors.
The Journal of experimental medicine 1984;160(2):398-410.
1984: K M Peterson; John F Alderete
Selective acquisition of plasma proteins by Trichomonas vaginalis and human lipoproteins as a growth requirement for this species.
Molecular and biochemical parasitology 1984;12(1):37-48.
1983: K M Peterson; Joel Baseman; John F Alderete
Treponema pallidum receptor binding proteins interact with fibronectin.
The Journal of experimental medicine 1983;157(6):1958-70.
1983: K M Peterson; John F Alderete
Acquisition of alpha 1-Antitrypsin by a pathogenic strain of Trichomonas vaginalis.
Infection and immunity 1983;40(2):640-6.
1982: K M Peterson; John F Alderete
Host plasma proteins on the surface of pathogenic Trichomonas vaginalis.
Infection and immunity 1982;37(2):755-62.