FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Sheue-Yann Cheng

Research Profile

Chemicals & Drugs

Living Beings

Physiology

Disorders

Anatomy

Concepts & Ideas

Molecular Sequence Data

Co-author Network

Publications

TOP 3
Won Gu Kim; Sheue-Yann Cheng
Thyroid hormone receptors and cancer.
Laura Fozzatti; Anthony N Hollenberg; Dong Wook Kim; Jeong Won Park; Mark C Willingham; Sheue-Yann Cheng
Nuclear receptor corepressor (NCOR1) regulates in vivo actions of a mutated thyroid hormone receptor α.
Won Gu Kim; Lisa Zhang; Xuguang Zhu; Electron Kebebew; Dong Wook Kim; Sheue-Yann Cheng
Reactivation of the silenced thyroid hormone receptor β gene expression delays thyroid tumor progression.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Sheue-Yann Cheng (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Won Gu Kim; Sheue-Yann Cheng
Thyroid hormone receptors and cancer.
Biochimica et biophysica acta 2013;1830(7):3928-36.
2013: Laura Fozzatti; Anthony N Hollenberg; Dong Wook Kim; Jeong Won Park; Mark C Willingham; Sheue-Yann Cheng
Nuclear receptor corepressor (NCOR1) regulates in vivo actions of a mutated thyroid hormone receptor α.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(19):7850-5.
2013: Won Gu Kim; Lisa Zhang; Xuguang Zhu; Electron Kebebew; Dong Wook Kim; Sheue-Yann Cheng
Reactivation of the silenced thyroid hormone receptor β gene expression delays thyroid tumor progression.
Endocrinology 2013;154(1):25-35.
2012: Li Zhao; Xuguang Zhu; Laura Fozzatti; Mark Willingham; Jeong Won Park; Sheue-Yann Cheng
Role of TSH in the spontaneous development of asymmetrical thyroid carcinoma in mice with a targeted mutation in a single allele of the thyroid hormone-β receptor.
Endocrinology 2012;153(10):5090-100.
2012: Rudy Bonavia; Webster K Cavenee; Sheue-Yann Cheng; P Hadwiger; M M Inda; Motoo Nagane; Dinah W Y Sah; P Tan; S Vandenberg; Frank B Furnari
EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway.
Oncogene 2012;31(36):4054-66.
2012: Rohit Anthony Sinha; Robert D Stevens; Scott A Summers; Boon-Huat Bay; Sheue-Yann Cheng; Mitchell A Lazar; Christopher B Newgard; Martin L Privalsky; Mobin M Siddique; Seo-Hee You; Jin Zhou; Xuguang Zhu; Paul M Yen
Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.
The Journal of clinical investigation 2012;122(7):2428-38.
2012: E Sandra Chocron; Lily Dong; Deborah Holstein; Jamal A Ibdah; Nuttawut Saelim; Naomi L Sayre; Xuguang Zhu; Sheue-Yann Cheng; James D Lechleiter
The trifunctional protein mediates thyroid hormone receptor-dependent stimulation of mitochondria metabolism.
Molecular endocrinology (Baltimore, Md.) 2012;26(7):1117-28.
2012: Patrick J O'Shea; Robert L Walker; Sheue-Yann Cheng; Sean Davis; Dong Wook Kim; John G Logan; Paul S Meltzer; Graham R Williams
Advanced bone formation in mice with a dominant-negative mutation in the thyroid hormone receptor β gene due to activation of Wnt/β-catenin protein signaling.
The Journal of biological chemistry 2012;287(21):17812-22.
2012: C Lu; Mark C Willingham; X Zhu; Sheue-Yann Cheng
Activation of tumor cell proliferation by thyroid hormone in a mouse model of follicular thyroid carcinoma.
Oncogene 2012;31(16):2007-16.
2012: Won Gu Kim; Changxue Lu; Jeong Won Park; Mark C Willingham; Laura Fozzatti; Celine J Guigon; Sheue-Yann Cheng
SKI-606, an Src inhibitor, reduces tumor growth, invasion, and distant metastasis in a mouse model of thyroid cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(5):1281-90.
2012: Emily A Cordas; Arturo Hernandez; Masahiro Kaneshige; Lily Ng; Sheue-Yann Cheng; Douglas Forrest
Thyroid hormone receptors control developmental maturation of the middle ear and the size of the ossicular bones.
Endocrinology 2012;153(3):1548-60.
2012: Dong Wook Kim; Mark Willingham; Li Zhao; John Hanover; Sheue-Yann Cheng
Thyroid hormone receptor β suppresses SV40-mediated tumorigenesis via novel nongenomic actions.
American journal of cancer research 2012;2(5):606-19.
2012: Xuguang Zhu; Sheue-Yann Cheng
Modeling follicular thyroid cancer for future therapies.
American journal of cancer research 2012;2(2):130-40.
2011: Laura Fozzatti; Oksana Gavrilova; Anthony N Hollenberg; Dong Wook Kim; Changxue Lu; Jeong Won Park; Mark C Willingham; Inna Astapova; Sheue-Yann Cheng
Resistance to thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1).
Proceedings of the National Academy of Sciences of the United States of America 2011;108(42):17462-7.
2011: Changxue Lu; Sheue-Yann Cheng
Extranuclear signaling of mutated thyroid hormone receptors in promoting metastatic spread in thyroid carcinogenesis.
Steroids 2011;76(9):885-91.
2011: Céline J Guigon; D W Kim; Mark C Willingham; Sheue-Yann Cheng
Mutation of thyroid hormone receptor-β in mice predisposes to the development of mammary tumors.
Oncogene 2011;30(30):3381-90.
2011: Laura Fozzatti; Changxue Lu; Dong-Wook Kim; Sheue-Yann Cheng
Differential recruitment of nuclear coregulators directs the isoform-dependent action of mutant thyroid hormone receptors.
Molecular endocrinology (Baltimore, Md.) 2011;25(6):908-21.
2011: XG Zhu; Michael L Goodson; Dong Wook Kim; Martin L Privalsky; Sheue-Yann Cheng
NCoR1 regulates thyroid hormone receptor isoform-dependent adipogenesis.
Journal of molecular endocrinology 2011;46(3):233-44.
2011: Joseph H Antin; Andrew E Aplin; Sheue-Yann Cheng; Vincent L Cryns; Michael R Emmert-Buck; Dengshun Wang
American journal of cancer research: editorial board (2011).
American journal of cancer research 2011;1(6):817-22.
2011: Jerome M Hershman; Sheue-Yann Cheng; Andrew G Gianoukakis
Update in thyroidology 2010.
The Journal of clinical endocrinology and metabolism 2011;96(1):9-14.
2010: Céline J Guigon; Dong Wook Kim; Xuguang Zhu; Li Zhao; Sheue-Yann Cheng
Tumor suppressor action of liganded thyroid hormone receptor beta by direct repression of beta-catenin gene expression.
Endocrinology 2010;151(11):5528-36.
2010: Maite Jauregui-Osoro; Kavitha Sunassee; Amanda J Weeks; David J Berry; Rowena L Paul; Marcel Cleij; Jasvinder Paul Banga; Michael J O'Doherty; Paul K Marsden; Susan E M Clarke; James R Ballinger; Istvan Szanda; Sheue-Yann Cheng; Philip J Blower
Synthesis and biological evaluation of [(18)F]tetrafluoroborate: a PET imaging agent for thyroid disease and reporter gene imaging of the sodium/iodide symporter.
European journal of nuclear medicine and molecular imaging 2010;37(11):2108-16.
2010: Xuguang Zhu; Sheue-Yann Cheng
New insights into regulation of lipid metabolism by thyroid hormone.
Current opinion in endocrinology, diabetes, and obesity 2010;17(5):408-13.
2010: Céline J Guigon; Laura Fozzatti; Changxue Lu; Mark C Willingham; Sheue-Yann Cheng
Inhibition of mTORC1 signaling reduces tumor growth but does not prevent cancer progression in a mouse model of thyroid cancer.
Carcinogenesis 2010;31(7):1284-91.
2010: Yue Huang; Celine J Guigon; Jun Fan; Sheue-Yann Cheng; Guo-Zhang Zhu
Pituitary homeobox 2 (PITX2) promotes thyroid carcinogenesis by activation of cyclin D2.
Cell cycle (Georgetown, Tex.) 2010;9(7):1333-41.
2010: Changxue Lu; Li Zhao; Hao Ying; Mark C Willingham; Sheue-Yann Cheng
Growth activation alone is not sufficient to cause metastatic thyroid cancer in a mouse model of follicular thyroid carcinoma.
Endocrinology 2010;151(4):1929-39.
2010: Alok Mishra; Xu-Guang Zhu; Kai Ge; Sheue-Yann Cheng
Adipogenesis is differentially impaired by thyroid hormone receptor mutant isoforms.
Journal of molecular endocrinology 2010;44(4):247-55.
2010: X-G Zhu; Li Zhao; Mark C Willingham; Sheue-Yann Cheng
Thyroid hormone receptors are tumor suppressors in a mouse model of metastatic follicular thyroid carcinoma.
Oncogene 2010;29(13):1909-19.
2010: Sheue-Yann Cheng; Jack L Leonard; Paul J Davis
Molecular aspects of thyroid hormone actions.
Endocrine reviews 2010;31(2):139-70.
2010: Changxue Lu; Sheue-Yann Cheng
Thyroid hormone receptors regulate adipogenesis and carcinogenesis via crosstalk signaling with peroxisome proliferator-activated receptors.
Journal of molecular endocrinology 2010;44(3):143-54.
2010: Miriam O Ribeiro; Suzy Bianco; Masahiro Kaneshige; James J Schultz; Sheue-Yann Cheng; Antonio Bianco; Gregory A Brent
Expression of uncoupling protein 1 in mouse brown adipose tissue is thyroid hormone receptor-beta isoform specific and required for adaptive thermogenesis.
Endocrinology 2010;151(1):432-40.
2009: Sheue-Yann Cheng; Matthew D Ringel
Frontiers in thyroid cancer: December 2009.
Thyroid : official journal of the American Thyroid Association 2009;19(12):1297-8.
2009: Celine J Guigon; Sheue-Yann Cheng
Novel non-genomic signaling of thyroid hormone receptors in thyroid carcinogenesis.
Molecular and cellular endocrinology 2009;308(1-2):63-9.
2009: Fumihiko Furuya; Changxue Lu; Celine J Guigon; Sheue-Yann Cheng
Nongenomic activation of phosphatidylinositol 3-kinase signaling by thyroid hormone receptors.
Steroids 2009;74(7):628-34.
2009: Céline J Guigon; Sheue-Yann Cheng
Novel oncogenic actions of TRbeta mutants in tumorigenesis.
IUBMB life 2009;61(5):528-36.
2009: Osamu Araki; Hao Ying; XG Zhu; Mark C Willingham; Sheue-Yann Cheng
Distinct dysregulation of lipid metabolism by unliganded thyroid hormone receptor isoforms.
Molecular endocrinology (Baltimore, Md.) 2009;23(3):308-15.
2009: Céline J Guigon; Li Zhao; Mark C Willingham; Sheue-Yann Cheng
PTEN deficiency accelerates tumour progression in a mouse model of thyroid cancer.
Oncogene 2009;28(4):509-17.
2008: Aleksandra Glogowska; Janette Pyka; Astrid Kehlen; Marek Los; Paul Perumal; Ekkehard Weber; Sheue-Yann Cheng; Cuong Hoang-Vu; Thomas Klonisch
The cytoplasmic domain of proEGF negatively regulates motility and elastinolytic activity in thyroid carcinoma cells.
Neoplasia (New York, N.Y.) 2008;10(10):1120-30.
2008: Céline J Guigon; Li Zhao; Changxue Lu; Mark C Willingham; Sheue-Yann Cheng
Regulation of beta-catenin by a novel nongenomic action of thyroid hormone beta receptor.
Molecular and cellular biology 2008;28(14):4598-608.
2008: Changxue Lu; Mark C Willingham; Fumihiko Furuya; Sheue-Yann Cheng
Activation of phosphatidylinositol 3-kinase signaling promotes aberrant pituitary growth in a mouse model of thyroid-stimulating hormone-secreting pituitary tumors.
Endocrinology 2008;149(7):3339-45.
2008: Hao Ying; Mark C Willingham; Sheue-Yann Cheng
The steroid receptor coactivator-3 is a tumor promoter in a mouse model of thyroid cancer.
Oncogene 2008;27(6):823-30.
2007: Patrick J O'Shea; Céline J Guigon; Graham R Williams; Sheue-Yann Cheng
Regulation of fibroblast growth factor receptor-1 (FGFR1) by thyroid hormone: identification of a thyroid hormone response element in the murine Fgfr1 promoter.
Endocrinology 2007;148(12):5966-76.
2007: Fumihiko Furuya; Changxue Lu; Mark C Willingham; Sheue-Yann Cheng
Inhibition of phosphatidylinositol 3-kinase delays tumor progression and blocks metastatic spread in a mouse model of thyroid cancer.
Carcinogenesis 2007;28(12):2451-8.
2007: Fumihiko Furuya; Céline J Guigon; Li Zhao; Changxue Lu; John Hanover; Sheue-Yann Cheng
Nuclear receptor corepressor is a novel regulator of phosphatidylinositol 3-kinase signaling.
Molecular and cellular biology 2007;27(17):6116-26.
2007: Caroline S Kim; Hao Ying; Mark C Willingham; Sheue-Yann Cheng
The pituitary tumor-transforming gene promotes angiogenesis in a mouse model of follicular thyroid cancer.
Carcinogenesis 2007;28(5):932-9.
2007: Hao Ying; Osamu Araki; Fumihiko Furuya; Yasuhito Kato; Sheue-Yann Cheng
Impaired adipogenesis caused by a mutated thyroid hormone alpha1 receptor.
Molecular and cellular biology 2007;27(6):2359-71.
2007: Caroline S Kim; Fumihiko Furuya; Hao Ying; Yasuhito Kato; John Hanover; Sheue-Yann Cheng
Gelsolin: a novel thyroid hormone receptor-beta interacting protein that modulates tumor progression in a mouse model of follicular thyroid cancer.
Endocrinology 2007;148(3):1306-12.
2007: Fumihiko Furuya; Hao Ying; Li Zhao; Sheue-Yann Cheng
Novel functions of thyroid hormone receptor mutants: beyond nucleus-initiated transcription.
Steroids 2007;72(2):171-9.
2006: Hao Ying; Fumihiko Furuya; Li Zhao; Osamu Araki; Brian L West; John Hanover; Mark C Willingham; Sheue-Yann Cheng
Aberrant accumulation of PTTG1 induced by a mutated thyroid hormone beta receptor inhibits mitotic progression.
The Journal of clinical investigation 2006;116(11):2972-84.
2006: Yukio Hiroi; Hyung-Hwan Kim; Hao Ying; Fumihiko Furuya; Zhihong Huang; Tommaso Simoncini; Kensuke Noma; Kojiro Ueki; Ngoc-Ha Nguyen; Thomas S Scanlan; Michael A Moskowitz; Sheue-Yann Cheng; James K Liao
Rapid nongenomic actions of thyroid hormone.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(38):14104-9.
2006: Y Kato; Hao Ying; Li Zhao; Fumihiko Furuya; Osamu Araki; Mark C Willingham; Sheue-Yann Cheng
PPARgamma insufficiency promotes follicular thyroid carcinogenesis via activation of the nuclear factor-kappaB signaling pathway.
Oncogene 2006;25(19):2736-47.
2006: William B Siesser; Jiali Zhao; L R Miller; Sheue-Yann Cheng; Michael P McDonald
Transgenic mice expressing a human mutant beta1 thyroid receptor are hyperactive, impulsive, and inattentive.
Genes, brain, and behavior 2006;5(3):282-97.
2006: Fumihiko Furuya; John Hanover; Sheue-Yann Cheng
Activation of phosphatidylinositol 3-kinase signaling by a mutant thyroid hormone beta receptor.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(6):1780-5.
2006: Patrick J O'Shea; J H Duncan Bassett; Sheue-Yann Cheng; Graham R Williams
Characterization of skeletal phenotypes of TRalpha1 and TRbeta mutant mice: implications for tissue thyroid status and T3 target gene expression.
Nuclear receptor signaling 2006;4():e011.
2005: Joanna C Barnard; Allan J Williams; Bénédicte Rabier; Olivier Chassande; Jacques Samarut; Sheue-Yann Cheng; J H Duncan Bassett; Graham R Williams
Thyroid hormones regulate fibroblast growth factor receptor signaling during chondrogenesis.
Endocrinology 2005;146(12):5568-80.
2005: Patrick J O'Shea; J H Duncan Bassett; Srividya Sriskantharajah; Hao Ying; Sheue-Yann Cheng; Graham R Williams
Contrasting skeletal phenotypes in mice with an identical mutation targeted to thyroid hormone receptor alpha1 or beta.
Molecular endocrinology (Baltimore, Md.) 2005;19(12):3045-59.
2005: Osamu Araki; Hao Ying; Fumihiko Furuya; Xuguang Zhu; Sheue-Yann Cheng
Thyroid hormone receptor beta mutants: Dominant negative regulators of peroxisome proliferator-activated receptor gamma action.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(45):16251-6.
2005: Caroline S Kim; Vasily Vasko; Yasuhito Kato; Michael J Kruhlak; Motoyasu Saji; Sheue-Yann Cheng; Matthew D Ringel
AKT activation promotes metastasis in a mouse model of follicular thyroid carcinoma.
Endocrinology 2005;146(10):4456-63.
2005: William B Siesser; Sheue-Yann Cheng; Michael P McDonald
Hyperactivity, impaired learning on a vigilance task, and a differential response to methylphenidate in the TRbetaPV knock-in mouse.
Psychopharmacology 2005;181(4):653-63.
2005: Hao Ying; Fumihiko Furuya; Mark C Willingham; Jianming Xu; Bert W O'Malley; Sheue-Yann Cheng
Dual functions of the steroid hormone receptor coactivator 3 in modulating resistance to thyroid hormone.
Molecular and cellular biology 2005;25(17):7687-95.
2005: Drazen Zimonjic; Yasuhito Kato; Hao Ying; Nicholas C Popescu; Sheue-Yann Cheng
Chromosomal aberrations in cell lines derived from thyroid tumors spontaneously developed in TRbetaPV/PV mice.
Cancer genetics and cytogenetics 2005;161(2):104-9.
2005: Sheue-Yann Cheng
Isoform-dependent actions of thyroid hormone nuclear receptors: lessons from knockin mutant mice.
Steroids 2005;70(5-7):450-4.
2005: Sheue-Yann Cheng
Thyroid hormone receptor mutations and disease: beyond thyroid hormone resistance.
Trends in endocrinology and metabolism: TEM 2005;16(4):176-82.
2005: Ann Marie Zavacki; Hao Ying; Marcelo A Christoffolete; Goele Aerts; Edward C So; John W Harney; Sheue-Yann Cheng; P Reed Larsen; Antonio Bianco
Type 1 iodothyronine deiodinase is a sensitive marker of peripheral thyroid status in the mouse.
Endocrinology 2005;146(3):1568-75.
2005: Hiroko Furumoto; Hao Ying; Gadisetti V R Chandramouli; Li Zhao; Robert L Walker; Paul S Meltzer; Mark C Willingham; Sheue-Yann Cheng
An unliganded thyroid hormone beta receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis.
Molecular and cellular biology 2005;25(1):124-35.
2004: Takanori Esaki; Hideyo Suzuki; Michelle Cook; Kazuaki Shimoji; Sheue-Yann Cheng; Louis Sokoloff; Jacques Nunez
Cardiac glucose utilization in mice with mutated alpha- and beta-thyroid hormone receptors.
American journal of physiology. Endocrinology and metabolism 2004;287(6):E1149-53.
2004: Yasuhito Kato; Hao Ying; Mark C Willingham; Sheue-Yann Cheng
A tumor suppressor role for thyroid hormone beta receptor in a mouse model of thyroid carcinogenesis.
Endocrinology 2004;145(10):4430-8.
2004: Sheue-Yann Cheng
Abnormalities of nuclear receptors in thyroid cancer.
Cancer treatment and research 2004;122():165-78.
2004: Lance D Miller; Peter McPhie; Hideyo Suzuki; Yasuhito Kato; Edison Liu; Sheue-Yann Cheng
Multi-tissue gene-expression analysis in a mouse model of thyroid hormone resistance.
Genome biology 2004;5(5):R31.
2003: Sheue-Yann Cheng
Thyroid hormone receptor mutations in cancer.
Molecular and cellular endocrinology 2003;213(1):23-30.
2003: Eric A Swanson; Bernd Gloss; Darrell D Belke; Masahiro Kaneshige; Sheue-Yann Cheng; Wolfgang H Dillmann
Cardiac expression and function of thyroid hormone receptor beta and its PV mutant.
Endocrinology 2003;144(11):4820-5.
2003: Hao Ying; Hideyo Suzuki; Li Zhao; Mark C Willingham; Paul Meltzer; Sheue-Yann Cheng
Mutant thyroid hormone receptor beta represses the expression and transcriptional activity of peroxisome proliferator-activated receptor gamma during thyroid carcinogenesis.
Cancer research 2003;63(17):5274-80.
2003: Yuji Kamiya; Xiao-Yong Zhang; Hao Ying; Yusuhito Kato; Mark C Willingham; Jianming Xu; Bert W O'Malley; Sheue-Yann Cheng
Modulation by steroid receptor coactivator-1 of target-tissue responsiveness in resistance to thyroid hormone.
Endocrinology 2003;144(9):4144-53.
2003: Takanori Esaki; Hideyo Suzuki; Michelle Cook; Kazuaki Shimoji; Sheue-Yann Cheng; Louis Sokoloff; Jacques Nunez
Functional activation of cerebral metabolism in mice with mutated thyroid hormone nuclear receptors.
Endocrinology 2003;144(9):4117-22.
2003: Hao Ying; Hideyo Suzuki; Hiroko Furumoto; Robert Walker; Paul Meltzer; Mark C Willingham; Sheue-Yann Cheng
Alterations in genomic profiles during tumor progression in a mouse model of follicular thyroid carcinoma.
Carcinogenesis 2003;24(9):1467-79.
2003: Hideyo Suzuki; Sheue-Yann Cheng
Compensatory role of thyroid hormone receptor (TR) alpha 1 in resistance to thyroid hormone: study in mice with a targeted mutation in the TR beta gene and deficient in TR alpha 1.
Molecular endocrinology (Baltimore, Md.) 2003;17(8):1647-55.
2003: Patrick J O'Shea; Clare B Harvey; Hideyo Suzuki; Masahiro Kaneshige; Kumiko Kaneshige; Sheue-Yann Cheng; Graham R Williams
A thyrotoxic skeletal phenotype of advanced bone formation in mice with resistance to thyroid hormone.
Molecular endocrinology (Baltimore, Md.) 2003;17(7):1410-24.
2003: Hideyo Suzuki; X-Y Zhang; D Forrest; Mark C Willingham; Sheue-Yann Cheng
Marked potentiation of the dominant negative action of a mutant thyroid hormone receptor beta in mice by the ablation of one wild-type beta allele.
Molecular endocrinology (Baltimore, Md.) 2003;17(5):895-907.
2002: Hideyo Suzuki; Mark C Willingham; Sheue-Yann Cheng
Mice with a mutation in the thyroid hormone receptor beta gene spontaneously develop thyroid carcinoma: a mouse model of thyroid carcinogenesis.
Thyroid : official journal of the American Thyroid Association 2002;12(11):963-9.
2002: Andrew J Griffith; Yvonne M Szymko; Masahiro Kaneshige; Rafael E Quiñónez; Kumiko Kaneshige; Kasey A Heintz; Mary Ann Mastroianni; Matthew W Kelley; Sheue-Yann Cheng
Knock-in mouse model for resistance to thyroid hormone (RTH): an RTH mutation in the thyroid hormone receptor beta gene disrupts cochlear morphogenesis.
Journal of the Association for Research in Otolaryngology : JARO 2002;3(3):279-88.
2002: Xiao-Yong Zhang; Masahiro Kaneshige; Yuji Kamiya; Kumiko Kaneshige; Peter McPhie; Sheue-Yann Cheng
Differential expression of thyroid hormone receptor isoforms dictates the dominant negative activity of mutant Beta receptor.
Molecular endocrinology (Baltimore, Md.) 2002;16(9):2077-92.
2002: Huei-Min Lin; Li Zhao; Sheue-Yann Cheng
Cyclin D1 Is a Ligand-independent Co-repressor for Thyroid Hormone Receptors.
The Journal of biological chemistry 2002;277(32):28733-41.
2002: Monika Puzianowska-Kuznicka; Agnieszka Krystyniak; Agnieszka Madej; Sheue-Yann Cheng; Janusz Nauman
Functionally impaired TR mutants are present in thyroid papillary cancer.
The Journal of clinical endocrinology and metabolism 2002;87(3):1120-8.
2002: Kwang-Huei Lin; Won-Jing Wang; Yi-Hsin Wu; Sheue-Yann Cheng
Activation of antimetastatic Nm23-H1 gene expression by estrogen and its alpha-receptor.
Endocrinology 2002;143(2):467-75.
2002: Yuji Kamiya; Monika Puzianowska-Kuznicka; Peter McPhie; Janusz Nauman; Sheue-Yann Cheng; Alicja Nauman
Expression of mutant thyroid hormone nuclear receptors is associated with human renal clear cell carcinoma.
Carcinogenesis 2002;23(1):25-33.
2001: Huei-Min Lin; Masahiro Kaneshige; Ling Zhao; X Zhang; John Hanover; Sheue-Yann Cheng
An isoform of branched-chain aminotransferase is a novel co-repressor for thyroid hormone nuclear receptors.
The Journal of biological chemistry 2001;276(51):48196-205.
2001: L D Miller; KS Park; Qingbin M Guo; Nawal W Alkharouf; Renae L Malek; Norman H Lee; Edison Liu; Sheue-Yann Cheng
Silencing of Wnt signaling and activation of multiple metabolic pathways in response to thyroid hormone-stimulated cell proliferation.
Molecular and cellular biology 2001;21(19):6626-39.
2001: Yoshiaki Itoh; Takanori Esaki; M Kaneshige; Hideyo Suzuki; Michelle Cook; Louis Sokoloff; Sheue-Yann Cheng; Jacques Nunez
Brain glucose utilization in mice with a targeted mutation in the thyroid hormone alpha or beta receptor gene.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(17):9913-8.
2000: XG Zhu; KS Park; Masahiro Kaneshige; MK Bhat; Q Zhu; C N Mariash; Peter McPhie; Sheue-Yann Cheng
The orphan nuclear receptor Ear-2 is a negative coregulator for thyroid hormone nuclear receptor function.
Molecular and cellular biology 2000;20(7):2604-18.
2000: Sheue-Yann Cheng
Multiple mechanisms for regulation of the transcriptional activity of thyroid hormone receptors.
Reviews in endocrine & metabolic disorders 2000;1(1-2):9-18.
1999: XG Zhu; Masahiro Kaneshige; A F Parlow; E Chen; R D Hunziker; M P McDonald; Sheue-Yann Cheng
Expression of the mutant thyroid hormone receptor PV in the pituitary of transgenic mice leads to weight reduction.
Thyroid : official journal of the American Thyroid Association 1999;9(11):1137-45.
1999: G Barrera-Hernandez; K S Park; A Dace; Qimin Zhan; Sheue-Yann Cheng
Thyroid hormone-induced cell proliferation in GC cells is mediated by changes in G1 cyclin/cyclin-dependent kinase levels and activity.
Endocrinology 1999;140(11):5267-74.
1999: MK Bhat; A Dace; Sheue-Yann Cheng
Tissue-specific differential repression of gene expression by a dominant negative mutant of thyroid hormone beta1 receptor.
Thyroid : official journal of the American Thyroid Association 1999;9(4):411-8.
1998: MP McDonald; R Wong; G Goldstein; Bruce D Weintraub; Sheue-Yann Cheng; Jacqueline N Crawley
Hyperactivity and learning deficits in transgenic mice bearing a human mutant thyroid hormone beta1 receptor gene.
Learning & memory (Cold Spring Harbor, N.Y.) 1998;5(4-5):289-301.
1998: G Barrera-Hernandez; Qimin Zhan; R Wong; Sheue-Yann Cheng
Thyroid hormone receptor is a negative regulator in p53-mediated signaling pathways.
DNA and cell biology 1998;17(9):743-50.
1997: Kwang-Huei Lin; XG Zhu; H C Hsu; S L Chen; HY Shieh; Szu-Tah Chen; Peter McPhie; Sheue-Yann Cheng
Dominant negative activity of mutant thyroid hormone alpha1 receptors from patients with hepatocellular carcinoma.
Endocrinology 1997;138(12):5308-15.
1997: Y T Ting; Sheue-Yann Cheng
Hormone-activated phosphorylation of human beta1 thyroid hormone nuclear receptor.
Thyroid : official journal of the American Thyroid Association 1997;7(3):463-9.
1997: XG Zhu; Peter McPhie; Kwang-Huei Lin; Sheue-Yann Cheng
The differential hormone-dependent transcriptional activation of thyroid hormone receptor isoforms is mediated by interplay of their domains.
The Journal of biological chemistry 1997;272(14):9048-54.
1997: XG Zhu; Peter McPhie; Sheue-Yann Cheng
Differential sensitivity of thyroid hormone receptor isoform homodimers and mutant heterodimers to hormone-induced dissociation from deoxyribonucleic acid: its role in dominant negative action.
Endocrinology 1997;138(4):1456-63.
1996: Kwang-Huei Lin; XG Zhu; H Y Shieh; H C Hsu; S T Chen; Peter McPhie; Sheue-Yann Cheng
Identification of naturally occurring dominant negative mutants of thyroid hormone alpha 1 and beta 1 receptors in a human hepatocellular carcinoma cell line.
Endocrinology 1996;137(10):4073-81.
1996: N Yap; C L Yu; Sheue-Yann Cheng
Modulation of the transcriptional activity of thyroid hormone receptors by the tumor suppressor p53.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):4273-7.
1996: XG Zhu; C L Yu; Peter McPhie; R Wong; Sheue-Yann Cheng
Understanding the molecular mechanism of dominant negative action of mutant thyroid hormone beta 1-receptors: the important role of the wild-type/mutant receptor heterodimer.
Endocrinology 1996;137(2):712-21.
1995: MK Bhat; Peter McPhie; Y T Ting; XG Zhu; Sheue-Yann Cheng
Structure of the carboxy-terminal region of thyroid hormone nuclear receptors and its possible role in hormone-dependent intermolecular interactions.
Biochemistry 1995;34(33):10591-9.
1995: MK Bhat; Peter McPhie; Sheue-Yann Cheng
Interaction of thyroid hormone nuclear receptor with antibody: characterization of the thyroid hormone binding site.
Biochemical and biophysical research communications 1995;210(2):464-71.
1995: R Wong; X G Zhu; M A Pineda; Sheue-Yann Cheng; Bruce D Weintraub
Cell type-dependent modulation of the dominant negative action of human mutant thyroid hormone beta 1 receptors.
Molecular medicine (Cambridge, Mass.) 1995;1(3):306-19.
1995: S C Meier-Heusler; X Zhu; Cristiana E Juge-Aubry; Agnès Pernin; Albert G Burger; Sheue-Yann Cheng; Christoph A Meier
Modulation of thyroid hormone action by mutant thyroid hormone receptors, c-erbA alpha 2 and peroxisome proliferator-activated receptor: evidence for different mechanisms of inhibition.
Molecular and cellular endocrinology 1995;107(1):55-66.
1994: MK Bhat; K Ashizawa; Sheue-Yann Cheng
Phosphorylation enhances the target gene sequence-dependent dimerization of thyroid hormone receptor with retinoid X receptor.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(17):7927-31.
1994: Sheue-Yann Cheng; S C Ransom; Peter McPhie; MK Bhat; A James Mixson; B D Wintraub
Analysis of the binding of 3,3',5-triiodo-L-thyronine and its analogues to mutant human beta 1 thyroid hormone receptors: a model of the hormone binding site.
Biochemistry 1994;33(14):4319-26.
1993: Christoph A Meier; C Parkison; A Chen; K Ashizawa; S C Meier-Heusler; P Muchmore; Sheue-Yann Cheng; Bruce D Weintraub
Interaction of human beta 1 thyroid hormone receptor and its mutants with DNA and retinoid X receptor beta. T3 response element-dependent dominant negative potency.
The Journal of clinical investigation 1993;92(4):1986-93.
1993: J B Park; K Ashizawa; C Parkison; Sheue-Yann Cheng
One-step immunoaffinity purification of human beta 1 thyroid hormone receptor with DNA and hormone binding activity.
Journal of biochemical and biophysical methods 1993;27(2):95-103.
1993: MK Bhat; C Parkison; Peter McPhie; C M Liang; Sheue-Yann Cheng
Conformational changes of human beta 1 thyroid hormone receptor induced by binding of 3,3',5-triiodo-L-thyronine.
Biochemical and biophysical research communications 1993;195(1):385-92.
1993: Peter McPhie; C Parkison; B K Lee; Sheue-Yann Cheng
Structure of the hormone binding domain of human beta 1 thyroid hormone nuclear receptor: is it an alpha/beta barrel?
Biochemistry 1993;32(29):7460-5.
1992: K Ashizawa; Sheue-Yann Cheng
Regulation of thyroid hormone receptor-mediated transcription by a cytosol protein.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(19):9277-81.
1992: K H Lin; K Ashizawa; Sheue-Yann Cheng
Phosphorylation stimulates the transcriptional activity of the human beta 1 thyroid hormone nuclear receptor.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7737-41.
1992: K Ashizawa; Sheue-Yann Cheng
A sensitive and rapid in situ immunoassay to quantitatively determine the cellular antigens in intact cultured cells.
Journal of biochemical and biophysical methods 1992;24(3-4):297-307.
1992: K Ashizawa; T Fukuda; Sheue-Yann Cheng
Transcriptional stimulation by thyroid hormone of a cytosolic thyroid hormone binding protein which is homologous to a subunit of pyruvate kinase M1.
Biochemistry 1992;31(10):2774-8.
1991: K H Lin; Sheue-Yann Cheng
An efficient method to purify active eukaryotic proteins from the inclusion bodies in Escherichia coli.
BioTechniques 1991;11(6):748, 750, 752-3.
1991: K Ashizawa; M C Willingham; C M Liang; Sheue-Yann Cheng
In vivo regulation of monomer-tetramer conversion of pyruvate kinase subtype M2 by glucose is mediated via fructose 1,6-bisphosphate.
The Journal of biological chemistry 1991;266(25):16842-6.
1991: C Parkison; K Ashizawa; Peter McPhie; K H Lin; Sheue-Yann Cheng
The monomer of pyruvate kinase, subtype M1, is both a kinase and a cytosolic thyroid hormone binding protein.
Biochemical and biophysical research communications 1991;179(1):668-74.
1991: K Ashizawa; Peter McPhie; K H Lin; Sheue-Yann Cheng
An in vitro novel mechanism of regulating the activity of pyruvate kinase M2 by thyroid hormone and fructose 1, 6-bisphosphate.
Biochemistry 1991;30(29):7105-11.
1991: K H Lin; M C Willingham; C M Liang; Sheue-Yann Cheng
Intracellular distribution of the endogenous and transfected beta form of thyroid hormone nuclear receptor visualized by the use of domain-specific monoclonal antibodies.
Endocrinology 1991;128(5):2601-9.
1991: K H Lin; C Parkison; Peter McPhie; Sheue-Yann Cheng
An essential role of domain D in the hormone-binding activity of human beta 1 thyroid hormone nuclear receptor.
Molecular endocrinology (Baltimore, Md.) 1991;5(4):485-92.
1991: K H Lin; Sheue-Yann Cheng
Zn+2 induces reversible cross-linking of human placental thyroid hormone nuclear receptor with no effect on hormone binding.
Biochemical and biophysical research communications 1991;175(1):250-5.
1990: N C Popescu; Sheue-Yann Cheng
Chromosomal localization of the gene for a human cytosolic thyroid hormone binding protein homologous to the subunit of pyruvate kinase, subtype M2.
Somatic cell and molecular genetics 1990;16(6):593-8.
1990: K H Lin; T Fukuda; Sheue-Yann Cheng
Hormone and DNA binding activity of a purified human thyroid hormone nuclear receptor expressed in Escherichia coli.
The Journal of biological chemistry 1990;265(9):5161-5.
1989: H Kato; T Velu; Sheue-Yann Cheng
High level expression of p55, a thyroid hormone binding protein which is homologous to protein disulfide isomerase in a retroviral vector.
Biochemical and biophysical research communications 1989;164(1):238-44.
1989: H Kato; T Fukuda; C Parkison; Peter McPhie; Sheue-Yann Cheng
Cytosolic thyroid hormone-binding protein is a monomer of pyruvate kinase.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(20):7861-5.
1989: C Parkison; H Kato; Sheue-Yann Cheng
The nucleotide sequence of a full length cDNA encoding rat pituitary pyruvate kinase.
Nucleic acids research 1989;17(17):7106.
1989: C Parkison; Sheue-Yann Cheng
A convenient method to increase the number of readable bases in DNA sequencing.
BioTechniques 1989;7(8):828-9.
1989: T Obata; T Fukuda; M C Willingham; C M Liang; Sheue-Yann Cheng
A cytoplasmic thyroid hormone binding protein: characterization using monoclonal antibodies.
Biochemistry 1989;28(2):617-23.
1988: T Fukuda; M C Willingham; Sheue-Yann Cheng
Antipeptide antibodies recognize c-erbA and a related protein in human A431 carcinoma cells.
Endocrinology 1988;123(6):2646-52.
1988: T Obata; Sheue-Yann Cheng
Strip-comb dot immunobinding: a rapid, easy and sensitive method to screen monoclonal antibodies.
BioTechniques 1988;6(4):299-303.
1988: N C Popescu; Sheue-Yann Cheng; Ira Pastan
Chromosomal localization of the gene for a human thyroid hormone-binding protein.
American journal of human genetics 1988;42(4):560-4.
1988: T Obata; T Fukuda; Sheue-Yann Cheng
Antibodies against the human cellular 3,3',5-triiodo-L-thyronine-binding protein (p 58).
FEBS letters 1988;230(1-2):9-12.
1988: Q H Gong; T Fukuda; C Parkison; Sheue-Yann Cheng
Nucleotide sequence of a full-length cDNA clone encoding a mouse cellular thyroid hormone binding protein (p55) that is homologous to protein disulfide isomerase and the beta-subunit of prolyl-4-hydroxylase.
Nucleic acids research 1988;16(3):1203.
1988: T Obata; S Kitagawa; Q H Gong; Ira Pastan; Sheue-Yann Cheng
Thyroid hormone down-regulates p55, a thyroid hormone-binding protein that is homologous to protein disulfide isomerase and the beta-subunit of prolyl-4-hydroxylase.
The Journal of biological chemistry 1988;263(2):782-5.
1987: Sheue-Yann Cheng; Q H Gong; C Parkison; E A Robinson; E Appella; G T Merlino; Ira Pastan
The nucleotide sequence of a human cellular thyroid hormone binding protein present in endoplasmic reticulum.
The Journal of biological chemistry 1987;262(23):11221-7.