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Tatyana Chernova

Research Profile

Chemicals & Drugs

Living Beings

Physiology

Lymphocyte Activation

Anatomy

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Publications

TOP 3
Yvette E Latchman; Spencer C Liang; Yin Wu; Tatyana Chernova; Raymond A Sobel; Martina Klemm; Vijay K Kuchroo; Gordon J Freeman; Arlene H Sharpe
PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells.
Nancy Rodig; Timothy Ryan; Jessica A Allen; Hong Pang; Nir Grabie; Tatyana Chernova; Edward Greenfield; Spencer C Liang; Arlene H Sharpe; Andrew H Lichtman; Gordon J Freeman
Endothelial expression of PD-L1 and PD-L2 down-regulates CD8+ T cell activation and cytolysis.
Michael J Eppihimer; Jason Gunn; Gordon J Freeman; Edward Greenfield; Tatyana Chernova; Jamie Erickson; John P Leonard
Expression and regulation of the PD-L1 immunoinhibitory molecule on microvascular endothelial cells.

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2004: Yvette E Latchman; Spencer C Liang; Yin Wu; Tatyana Chernova; Raymond A Sobel; Martina Klemm; Vijay K Kuchroo; Gordon J Freeman; Arlene H Sharpe
PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(29):10691-6.
2003: Nancy Rodig; Timothy Ryan; Jessica A Allen; Hong Pang; Nir Grabie; Tatyana Chernova; Edward Greenfield; Spencer C Liang; Arlene H Sharpe; Andrew H Lichtman; Gordon J Freeman
Endothelial expression of PD-L1 and PD-L2 down-regulates CD8+ T cell activation and cytolysis.
European journal of immunology 2003;33(11):3117-26.
2002: Michael J Eppihimer; Jason Gunn; Gordon J Freeman; Edward Greenfield; Tatyana Chernova; Jamie Erickson; John P Leonard
Expression and regulation of the PD-L1 immunoinhibitory molecule on microvascular endothelial cells.
Microcirculation (New York, N.Y. : 1994) 2002;9(2):133-45.
2002: Laurent Monney; Catherine A Sabatos; Jason L Gaglia; Akemi Ryu; Hanspeter Waldner; Tatyana Chernova; Stephen Manning; Edward Greenfield; Anthony J Coyle; Raymond A Sobel; Gordon J Freeman; Vijay K Kuchroo
Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease.
Nature 2002;415(6871):536-41.
2001: Yvette E Latchman; Clive R Wood; Tatyana Chernova; Divya Chaudhary; M Borde; Irina Chernova; Yoshiko Iwai; AJ Long; Julia A Brown; R Nunes; Edward Greenfield; K Bourque; Vassiliki A Boussiotis; Laura L Carter; Beatriz M Carreno; N Malenkovich; H Nishimura; T Okazaki; Tasuku Honjo; Arlene H Sharpe; Gordon J Freeman
PD-L2 is a second ligand for PD-1 and inhibits T cell activation.
Nature immunology 2001;2(3):261-8.
2001: Alexander J McAdam; Rebecca J Greenwald; M A Levin; Tatyana Chernova; N Malenkovich; Vincent Ling; Gordon J Freeman; Arlene H Sharpe
ICOS is critical for CD40-mediated antibody class switching.
Nature 2001;409(6816):102-5.
2000: Alexander J McAdam; Tammy T Chang; A E Lumelsky; Edward Greenfield; Vassiliki A Boussiotis; Jonathan S Duke-Cohan; Tatyana Chernova; N Malenkovich; Claudia Jabs; Vijay K Kuchroo; Vincent Ling; Mary Collins; Arlene H Sharpe; Gordon J Freeman
Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(9):5035-40.
2000: Gordon J Freeman; AJ Long; Yoshiko Iwai; K Bourque; Tatyana Chernova; H Nishimura; Lori Fitz; N Malenkovich; T Okazaki; Michael C Byrne; Heidi F Horton; Lynette A Fouser; LauraL Carter; Vincent Ling; M R Bowman; Beatriz M Carreno; Mary Collins; Clive R Wood; Tasuku Honjo
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation.
The Journal of experimental medicine 2000;192(7):1027-34.