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Elena Chertova

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Gregory Q Del Prete; Ronald C Desrosiers; Luis D Giavedoni; Dan H Barouch; Elena Chertova; Jeffrey D Lifson; Preston A Marx; Christopher J Miller; Laura Newman; David H O'Connor; Kelli Oswald; Ranajit Pal; Laura M Parodi; Michael Piatak; Carolyn Reid; James D Roser; Matthew Scarlotta; Brandon F Keele
Comparative characterization of transfection- and infection-derived simian immunodeficiency virus challenge stocks for in vivo nonhuman primate studies.
Cristina Bergamaschi; Elena Chertova; Barbara K Felber; Candido Alicea; Rachel Kelly Beach; Jenifer Bear; Margherita Rosati; STEVEN ROSENBERG; Raymond Sowder; George Pavlakis
Circulating IL-15 exists as heterodimeric complex with soluble IL-15Rα in human and mouse serum.
Gregory Q Del Prete; Jacob D Estes; Xing Pei Hao; Mary F Kearney; Brandon F Keele; Vineet N KewalRamani; Abigail Lara; Kyeongeun Lee; Rhonda Macallister; Kunio Nagashima; Vinay K Pathak; James D Roser; Jeremy Smedley; Jon Spindler; Charles M Trubey; Ann Wiegand; Julian W Bess; Chawaree Chaipan; Elena Chertova; John M Coffin; Jeffrey D Lifson
Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques.

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All Publications

2013: Gregory Q Del Prete; Ronald C Desrosiers; Luis D Giavedoni; Dan H Barouch; Elena Chertova; Jeffrey D Lifson; Preston A Marx; Christopher J Miller; Laura Newman; David H O'Connor; Kelli Oswald; Ranajit Pal; Laura M Parodi; Michael Piatak; Carolyn Reid; James D Roser; Matthew Scarlotta; Brandon F Keele
Comparative characterization of transfection- and infection-derived simian immunodeficiency virus challenge stocks for in vivo nonhuman primate studies.
Journal of virology 2013;87(8):4584-95.
2012: Cristina Bergamaschi; Elena Chertova; Barbara K Felber; Candido Alicea; Rachel Kelly Beach; Jenifer Bear; Margherita Rosati; STEVEN ROSENBERG; Raymond Sowder; George Pavlakis
Circulating IL-15 exists as heterodimeric complex with soluble IL-15Rα in human and mouse serum.
Blood 2012;120(1):e1-8.
2012: Gregory Q Del Prete; Jacob D Estes; Xing Pei Hao; Mary F Kearney; Brandon F Keele; Vineet N KewalRamani; Abigail Lara; Kyeongeun Lee; Rhonda Macallister; Kunio Nagashima; Vinay K Pathak; James D Roser; Jeremy Smedley; Jon Spindler; Charles M Trubey; Ann Wiegand; Julian W Bess; Chawaree Chaipan; Elena Chertova; John M Coffin; Jeffrey D Lifson
Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques.
Journal of virology 2012;86(6):3152-66.
2010: Abdul A Waheed; Sherimay Ablan; Raymond C Sowder; James D Roser; Carl P Schaffner; Elena Chertova; Eric O Freed
Effect of mutations in the human immunodeficiency virus type 1 protease on cleavage of the gp41 cytoplasmic tail.
Journal of virology 2010;84(6):3121-6.
2008: Ping Zhu; Hanspeter Winkler; Elena Chertova; Kenneth A Taylor; Kenneth H Roux
Cryoelectron tomography of HIV-1 envelope spikes: further evidence for tripod-like legs.
PLoS pathogens 2008;4(11):e1000203.
2008: Jacob T Minang; Matthew T Trivett; Lori V Coren; Eugene V Barsov; Michael Piatak; Oleg Chertov; Elena Chertova; David E Ott; Claes Ohlen
The Mamu B 17-restricted SIV Nef IW9 to TW9 mutation abrogates correct epitope processing and presentation without loss of replicative fitness.
Virology 2008;375(1):307-14.
2007: Lori V Coren; James A Thomas; Elena Chertova; Raymond C Sowder; Tracy D Gagliardi; Robert J Gorelick; David E Ott
Mutational analysis of the C-terminal gag cleavage sites in human immunodeficiency virus type 1.
Journal of virology 2007;81(18):10047-54.
2007: Abdul A Waheed; Sherimay Ablan; James D Roser; Raymond C Sowder; Carl P Schaffner; Elena Chertova; Eric O Freed
HIV-1 escape from the entry-inhibiting effects of a cholesterol-binding compound via cleavage of gp41 by the viral protease.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(20):8467-71.
2007: Hongzhan Xu; Elena Chertova; Jianbo Chen; David E Ott; James D Roser; Wei-Shau Hu; Vinay K Pathak
Stoichiometry of the antiviral protein APOBEC3G in HIV-1 virions.
Virology 2007;360(2):247-56.
2006: Elena Chertova; Oleg Chertov; Lori V Coren; James D Roser; Charles M Trubey; Julian W Bess; Raymond C Sowder; Eugene V Barsov; Brian L Hood; Robert J Fisher; Kunio Nagashima; Thomas P Conrads; Timothy D Veenstra; Jeffrey D Lifson; David E Ott
Proteomic and biochemical analysis of purified human immunodeficiency virus type 1 produced from infected monocyte-derived macrophages.
Journal of virology 2006;80(18):9039-52.
2006: Ping Zhu; Jun Liu; Julian W Bess; Elena Chertova; Jeffrey D Lifson; Henry Grisé; Gilad A Ofek; Kenneth A Taylor; Kenneth H Roux
Distribution and three-dimensional structure of AIDS virus envelope spikes.
Nature 2006;441(7095):847-52.
2005: Yossef Raviv; Mathias Viard; Julian W Bess; Elena Chertova; Robert Blumenthal
Inactivation of retroviruses with preservation of structural integrity by targeting the hydrophobic domain of the viral envelope.
Journal of virology 2005;79(19):12394-400.
2005: Mark K Louder; Anna Sambor; Elena Chertova; Tai Hunte; Sarah Barrett; Fallon Ojong; eric sanders-buell; Susan Zolla-Pazner; Francine E McCutchan; James D Roser; Dana Gabuzda; Jeffrey D Lifson; John R Mascola
HIV-1 envelope pseudotyped viral vectors and infectious molecular clones expressing the same envelope glycoprotein have a similar neutralization phenotype, but culture in peripheral blood mononuclear cells is associated with decreased neutralization sensitivity.
Virology 2005;339(2):226-38.
2005: David R Morcock; James A Thomas; Tracy D Gagliardi; Robert J Gorelick; James D Roser; Elena Chertova; Julian W Bess; David E Ott; Quentin J Sattentau; Ines Frank; Melissa Pope; Jeffrey D Lifson; Louis E. Henderson; Bruce J Crise
Elimination of retroviral infectivity by N-ethylmaleimide with preservation of functional envelope glycoproteins.
Journal of virology 2005;79(3):1533-42.
2004: Jeffrey D Lifson; Jeffrey L Rossio; Michael Piatak; Julian W Bess; Elena Chertova; Douglas K Schneider; Vicky J Coalter; Barbara Poore; Rebecca F Kiser; Robert J Imming; Anthony J Scarzello; Louis E. Henderson; W Gregory Alvord; Vanessa M Hirsch; Raoul E Benveniste; Larry O Arthur
Evaluation of the safety, immunogenicity, and protective efficacy of whole inactivated simian immunodeficiency virus (SIV) vaccines with conformationally and functionally intact envelope glycoproteins.
AIDS research and human retroviruses 2004;20(7):772-87.
2003: Ping Zhu; Elena Chertova; Julian W Bess; Jeffrey D Lifson; Larry O Arthur; Jun Liu; Kenneth A Taylor; Kenneth H Roux
Electron tomography analysis of envelope glycoprotein trimers on HIV and simian immunodeficiency virus virions.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(26):15812-7.
2003: Charles M Trubey; Elena Chertova; Lori V Coren; Joanne M Hilburn; Catherine V Hixson; Kunio Nagashima; Jeffrey D Lifson; David E Ott
Quantitation of HLA class II protein incorporated into human immunodeficiency type 1 virions purified by anti-CD45 immunoaffinity depletion of microvesicles.
Journal of virology 2003;77(23):12699-709.
2003: David Raymond Graham; Elena Chertova; Joanne M Hilburn; Larry O Arthur; James E K Hildreth
Cholesterol depletion of human immunodeficiency virus type 1 and simian immunodeficiency virus with beta-cyclodextrin inactivates and permeabilizes the virions: evidence for virion-associated lipid rafts.
Journal of virology 2003;77(15):8237-48.
2003: Nathan C Gaddis; Elena Chertova; Ann M Sheehy; Louis E. Henderson; Michael H Malim
Comprehensive investigation of the molecular defect in vif-deficient human immunodeficiency virus type 1 virions.
Journal of virology 2003;77(10):5810-20.
2003: David E Ott; Lori V Coren; Elena Chertova; Tracy D Gagliardi; Kunio Nagashima; Raymond C Sowder; Dexter Poon; Robert J Gorelick
Elimination of protease activity restores efficient virion production to a human immunodeficiency virus type 1 nucleocapsid deletion mutant.
Journal of virology 2003;77(10):5547-56.
2003: Elena Chertova; Bruce J Crise; David R Morcock; Julian W Bess; Louis E. Henderson; Jeffrey D Lifson
Sites, mechanism of action and lack of reversibility of primate lentivirus inactivation by preferential covalent modification of virion internal proteins.
Current molecular medicine 2003;3(3):265-72.
2002: Jeffrey D Lifson; Michael Piatak; Jeffrey L Rossio; Julian W Bess; Elena Chertova; D Schneider; Rebecca F Kiser; Vicky J Coalter; Barbara Poore; Robert J Imming; R C Desrosiers; Louis E. Henderson; Larry O Arthur
Whole inactivated SIV virion vaccines with functional envelope glycoproteins: safety, immunogenicity, and activity against intrarectal challenge.
Journal of medical primatology 2002;31(4-5):205-16.
2002: Elena Chertova; Julian W Bess; Bruce J Crise; Raymond C Sowder II; Terra M Schaden; Joanne M Hilburn; James A Hoxie; Raoul E Benveniste; Jeffrey D Lifson; Louis E. Henderson; Larry O Arthur
Envelope glycoprotein incorporation, not shedding of surface envelope glycoprotein (gp120/SU), Is the primary determinant of SU content of purified human immunodeficiency virus type 1 and simian immunodeficiency virus.
Journal of virology 2002;76(11):5315-25.
2002: Dexter Poon; Elena Chertova; David E Ott
Human immunodeficiency virus type 1 preferentially encapsidates genomic RNAs that encode Pr55(Gag): functional linkage between translation and RNA packaging.
Virology 2002;293(2):368-78.
2001: Igor A Topol; C McGrath; Elena Chertova; CO Dasenbrock; William R LaCourse; M A Eissenstat; Stanley K Burt; Louis E. Henderson; Jose R Casas-Finet
Experimental determination and calculations of redox potential descriptors of compounds directed against retroviral zinc fingers: Implications for rational drug design.
Protein science : a publication of the Protein Society 2001;10(7):1434-45.
2001: MARK ESSER; Julian W Bess; K Suryanarayana; Elena Chertova; D Marti; M Carrington; Larry O Arthur; Jeffrey D Lifson
Partial activation and induction of apoptosis in CD4(+) and CD8(+) T lymphocytes by conformationally authentic noninfectious human immunodeficiency virus type 1.
Journal of virology 2001;75(3):1152-64.
2001: JL Yovandich; Elena Chertova; Bradley P Kane; Tracy D Gagliardi; Julian W Bess; Raymond C Sowder; Louis E. Henderson; Robert J Gorelick
Alteration of zinc-binding residues of simian immunodeficiency virus p8(NC) results in subtle differences in gag processing and virion maturation associated with degradative loss of mutant NC.
Journal of virology 2001;75(1):115-24.
2000: David E Ott; Lori V Coren; Elena Chertova; Tracy D Gagliardi; Ulrich Schubert
Ubiquitination of HIV-1 and MuLV Gag.
Virology 2000;278(1):111-21.
2000: Ulrich Schubert; David E Ott; Elena Chertova; Reinhold Welker; Uwe Tessmer; Michael F Princiotta; Jack R Bennink; H G Krausslich; jon yewdell
Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(24):13057-62.
1999: David E Ott; Elena Chertova; L K Busch; Lori V Coren; Tracy D Gagliardi; Donald G Johnson
Mutational analysis of the hydrophobic tail of the human immunodeficiency virus type 1 p6(Gag) protein produces a mutant that fails to package its envelope protein.
Journal of virology 1999;73(1):19-28.
1998: Elena Chertova; Bradley P Kane; C McGrath; Donald G Johnson; Raymond C Sowder; Larry O Arthur; Louis E. Henderson
Probing the topography of HIV-1 nucleocapsid protein with the alkylating agent N-ethylmaleimide.
Biochemistry 1998;37(51):17890-7.
1998: Larry O Arthur; Julian W Bess; Elena Chertova; Jeffrey L Rossio; MARK ESSER; Raoul E Benveniste; Louis E. Henderson; Jeffrey D Lifson
Chemical inactivation of retroviral infectivity by targeting nucleocapsid protein zinc fingers: a candidate SIV vaccine.
AIDS research and human retroviruses 1998;14 Suppl 3():S311-9.
1998: Jeffrey L Rossio; MARK ESSER; K Suryanarayana; Douglas K Schneider; Julian W Bess; GM Vasquez; TA Wiltrout; Elena Chertova; M K Grimes; Quentin J Sattentau; Larry O Arthur; Louis E. Henderson; Jeffrey D Lifson
Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins.
Journal of virology 1998;72(10):7992-8001.
1996: David E Ott; Lori V Coren; Bradley P Kane; L K Busch; Donald G Johnson; Raymond C Sowder; Elena Chertova; Larry O Arthur; Louis E. Henderson
Cytoskeletal proteins inside human immunodeficiency virus type 1 virions.
Journal of virology 1996;70(11):7734-43.