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Ambrose Cheung
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18
Manna, Adhar
13
Bayer, Arnold
10
Fischetti, Vincent
10
Yeaman, Michael
8
Van Wamel, Willem
8
Xiong, Yan-Qiong
6
Donegan, Niles
4
Gresham, Hattie
4
Nast, Cynthia
4
Heinrichs, Jon
4
Sullam, Paul
3
Ingavale, Susham
3
Jarry, Todd
3
Chien, Y
2
Cheng, Genhong
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All Publications
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2009: Cheung Ambrose L; Yang Soo-Jin; Bayer Arnold S; Xiong Yan Q
Disparity in the in vitro versus in vivo regulation of fibronectin-binding proteins by 2 global regulators, saeRS and sigB, in Staphylococcus aureus.
The Journal of infectious diseases 2009;200(9):1371-4.
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2009: Lauderdale Katherine J; Boles Blaise R; Cheung Ambrose L; Horswill Alexander R
Interconnections between Sigma B, agr, and proteolytic activity in Staphylococcus aureus biofilm maturation.
Infection and immunity 2009;77(4):1623-35.
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2009: Donegan Niles P; Cheung Ambrose L
Regulation of the mazEF toxin-antitoxin module in Staphylococcus aureus and its impact on sigB expression.
Journal of bacteriology 2009;191(8):2795-805.
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2009: Fu Zhibiao; Tamber Sandeep; Memmi Guido; Donegan Niles P; Cheung Ambrose L
Overexpression of MazFsa in Staphylococcus aureus induces bacteriostasis by selectively targeting mRNAs for cleavage.
Journal of bacteriology 2009;191(7):2051-9.
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2009: Trotonda María Pilar; Xiong Yan Q; Memmi Guido; Bayer Arnold S; Cheung Ambrose L
Role of mgrA and sarA in methicillin-resistant Staphylococcus aureus autolysis and resistance to cell wall-active antibiotics.
The Journal of infectious diseases 2009;199(2):209-18.
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2008: Peterson M Michal; Mack Jessica L; Hall Pamela R; Alsup Anny A; Alexander Susan M; Sully Erin K; Sawires Youhanna S; Cheung Ambrose L; Otto Michael; Gresham Hattie D
Apolipoprotein B Is an innate barrier against invasive Staphylococcus aureus infection.
Cell host & microbe 2008;4(6):555-66.
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2008: von Köckritz-Blickwede Maren; Rohde Manfred; Oehmcke Sonja; Miller Lloyd S; Cheung Ambrose L; Herwald Heiko; Foster Simon; Medina Eva
Immunological mechanisms underlying the genetic predisposition to severe Staphylococcus aureus infection in the mouse model.
The American journal of pathology 2008;173(6):1657-68.
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2008: Trotonda María Pilar; Tamber Sandeep; Memmi Guido; Cheung Ambrose L
MgrA represses biofilm formation in Staphylococcus aureus.
Infection and immunity 2008;76(12):5645-54.
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2008: Jarry Todd M; Memmi Guido; Cheung Ambrose L
The expression of alpha-haemolysin is required for Staphylococcus aureus phagosomal escape after internalization in CFT-1 cells.
Cellular microbiology 2008;10(9):1801-14.
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2008: Kim Min-Ho; Liu Wei; Borjesson Dori L; Curry Fitz-Roy E; Miller Lloyd S; Cheung Ambrose L; Liu Fu-Tong; Isseroff R Rivkah; Simon Scott I
Dynamics of neutrophil infiltration during cutaneous wound healing and infection using fluorescence imaging.
The Journal of investigative dermatology 2008;128(7):1812-20.
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2008: Shanks Robert M Q; Meehl Michael A; Brothers Kimberly M; Martinez Raquel M; Donegan Niles P; Graber Martha L; Cheung Ambrose L; O'Toole George A
Genetic evidence for an alternative citrate-dependent biofilm formation pathway in Staphylococcus aureus that is dependent on fibronectin binding proteins and the GraRS two-component regulatory system.
Infection and immunity 2008;76(6):2469-77.
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2008: Cheung Ambrose L; Nishina Koren; Manna Adhar C
SarA of Staphylococcus aureus binds to the sarA promoter to regulate gene expression.
Journal of bacteriology 2008;190(6):2239-43.
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2008: Cheung Ambrose L; Nishina Koren A; Trotonda Maria Pilar; Tamber Sandeep
The SarA protein family of Staphylococcus aureus.
The international journal of biochemistry & cell biology 2008;40(3):355-61.
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2007: Fu Zhibiao; Donegan Niles P; Memmi Guido; Cheung Ambrose L
Characterization of MazFSa, an endoribonuclease from Staphylococcus aureus.
Journal of bacteriology 2007;189(24):8871-9.
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2007: Miller Lloyd S; Pietras Eric M; Uricchio Lawrence H; Hirano Kathleen; Rao Shyam; Lin Heping; O'Connell Ryan M; Iwakura Yoichiro; Cheung Ambrose L; Cheng Genhong; Modlin Robert L
Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(10):6933-42.
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2007: Kielian Tammy; Esen Nilufer; Liu Shuliang; Phulwani Nirmal K; Syed Mohsin M; Phillips Napoleon; Nishina Koren; Cheung Ambrose L; Schwartzman Joseph D; Ruhe Jorg J
Minocycline modulates neuroinflammation independently of its antimicrobial activity in staphylococcus aureus-induced brain abscess.
The American journal of pathology 2007;171(4):1199-214.
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2007: Sedlacek Martin; Gemery John M; Cheung Ambrose L; Bayer Arnold S; Remillard Brian D
Aspirin treatment is associated with a significantly decreased risk of Staphylococcus aureus bacteremia in hemodialysis patients with tunneled catheters.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2007;49(3):401-8.
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2007: Cheung Ambrose L; Bayles Kenneth W
Tissue culture assays used to analyze invasion by Staphylococcus aureus.
Current protocols in microbiology 2007;Chapter 9():Unit 9C.4.
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2007: Cheung Ambrose L
Isolation and culture of human umbilical vein endothelial cells (HUVEC).
Current protocols in microbiology 2007;Appendix 4():Appendix 4B.
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2006: Xiong Yan Q; Willard Julie; Yeaman Michael R; Cheung Ambrose L; Bayer Arnold S
Regulation of Staphylococcus aureus alpha-toxin gene (hla) expression by agr, sarA, and sae in vitro and in experimental infective endocarditis.
The Journal of infectious diseases 2006;194(9):1267-75.
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2006: Manna Adhar C; Cheung Ambrose L
Expression of SarX, a negative regulator of agr and exoprotein synthesis, is activated by MgrA in Staphylococcus aureus.
Journal of bacteriology 2006;188(12):4288-99.
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2006: Manna Adhar C; Cheung Ambrose L
Transcriptional regulation of the agr locus and the identification of DNA binding residues of the global regulatory protein SarR in Staphylococcus aureus.
Molecular microbiology 2006;60(5):1289-301.
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2006: Jarry Todd M; Cheung Ambrose L
Staphylococcus aureus escapes more efficiently from the phagosome of a cystic fibrosis bronchial epithelial cell line than from its normal counterpart.
Infection and immunity 2006;74(5):2568-77.
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2006: Liu Yingfang; Manna Adhar C; Pan Cheol-Ho; Kriksunov Irina A; Thiel Daniel J; Cheung Ambrose L; Zhang Gongyi
Structural and function analyses of the global regulatory protein SarA from Staphylococcus aureus.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2392-7.
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2006: Miller Lloyd S; O'Connell Ryan M; Gutierrez Miguel A; Pietras Eric M; Shahangian Arash; Gross Catherine E; Thirumala Ajaykumar; Cheung Ambrose L; Cheng Genhong; Modlin Robert L
MyD88 mediates neutrophil recruitment initiated by IL-1R but not TLR2 activation in immunity against Staphylococcus aureus.
Immunity 2006;24(1):79-91.
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2006: Bayer Arnold S; McNamara Peter; Yeaman Michael R; Lucindo Natalie; Jones Tiffanny; Cheung Ambrose L; Sahl Hans-Georg; Proctor Richard A
Transposon disruption of the complex I NADH oxidoreductase gene (snoD) in Staphylococcus aureus is associated with reduced susceptibility to the microbicidal activity of thrombin-induced platelet microbicidal protein 1.
Journal of bacteriology 2006;188(1):211-22.
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2005: Trotonda María Pilar; Manna Adhar C; Cheung Ambrose L; Lasa Iñigo; Penadés José R
SarA positively controls bap-dependent biofilm formation in Staphylococcus aureus.
Journal of bacteriology 2005;187(16):5790-8.
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2005: Shanks Robert M Q; Donegan Niles P; Graber Martha L; Buckingham Sarah E; Zegans Michael E; Cheung Ambrose L; O'Toole George A
Heparin stimulates Staphylococcus aureus biofilm formation.
Infection and immunity 2005;73(8):4596-606.
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2005: Haslinger-Löffler Bettina; Kahl Barbara C; Grundmeier Matthias; Strangfeld Katrin; Wagner Britta; Fischer Ute; Cheung Ambrose L; Peters Georg; Schulze-Osthoff Klaus; Sinha Bhanu
Multiple virulence factors are required for Staphylococcus aureus-induced apoptosis in endothelial cells.
Cellular microbiology 2005;7(8):1087-97.
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2005: Cheung Ambrose L; Manna Adhar C
Role of the distal sarA promoters in SarA expression in Staphylococcus aureus.
Infection and immunity 2005;73(7):4391-4.
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2005: Kahl Barbara C; Belling Gunnar; Becker Petra; Chatterjee Indranil; Wardecki Katrin; Hilgert Karin; Cheung Ambrose L; Peters Georg; Herrmann Mathias
Thymidine-dependent Staphylococcus aureus small-colony variants are associated with extensive alterations in regulator and virulence gene expression profiles.
Infection and immunity 2005;73(7):4119-26.
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2005: Tormo María Angeles; Martí Miguel; Valle Jaione; Manna Adhar C; Cheung Ambrose L; Lasa Iñigo; Penadés José R
SarA is an essential positive regulator of Staphylococcus epidermidis biofilm development.
Journal of bacteriology 2005;187(7):2348-56.
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2005: Ingavale Susham; van Wamel Willem; Luong Thanh T; Lee Chia Y; Cheung Ambrose L
Rat/MgrA, a regulator of autolysis, is a regulator of virulence genes in Staphylococcus aureus.
Infection and immunity 2005;73(3):1423-31.
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2004: Rothfork Jacob M; Timmins Graham S; Harris Michael N; Chen Xian; Lusis Aldons J; Otto Michael; Cheung Ambrose L; Gresham Hattie D
Inactivation of a bacterial virulence pheromone by phagocyte-derived oxidants: new role for the NADPH oxidase in host defense.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(38):13867-72.
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2004: Manna Adhar C; Ingavale Susham S; Maloney MaryBeth; van Wamel Willem; Cheung Ambrose L
Identification of sarV (SA2062), a new transcriptional regulator, is repressed by SarA and MgrA (SA0641) and involved in the regulation of autolysis in Staphylococcus aureus.
Journal of bacteriology 2004;186(16):5267-80.
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2004: Xiong Yan-Qiong; Bayer Arnold S; Yeaman Michael R; Van Wamel Willem; Manna Adhar C; Cheung Ambrose L
Impacts of sarA and agr in Staphylococcus aureus strain Newman on fibronectin-binding protein A gene expression and fibronectin adherence capacity in vitro and in experimental infective endocarditis.
Infection and immunity 2004;72(3):1832-6.
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2004: Bisognano Carmelo; Kelley William L; Estoppey Tristan; Francois Patrice; Schrenzel Jacques; Li Dongmei; Lew Daniel P; Hooper David C; Cheung Ambrose L; Vaudaux Pierre
A recA-LexA-dependent pathway mediates ciprofloxacin-induced fibronectin binding in Staphylococcus aureus.
The Journal of biological chemistry 2004;279(10):9064-71.
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2004: Cheung Ambrose L; Bayer Arnold S; Zhang Gongyi; Gresham Hattie; Xiong Yan-Qiong
Regulation of virulence determinants in vitro and in vivo in Staphylococcus aureus.
FEMS immunology and medical microbiology 2004;40(1):1-9.
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2003: Rothfork Jacob M; Dessus-Babus Sophie; Van Wamel Willem J B; Cheung Ambrose L; Gresham Hattie D
Fibrinogen depletion attenuates Staphyloccocus aureus infection by preventing density-dependent virulence gene up-regulation.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(10):5389-95.
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2003: Schmidt Katherine A; Manna Adhar C; Cheung Ambrose L
SarT influences sarS expression in Staphylococcus aureus.
Infection and immunity 2003;71(9):5139-48.
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2003: Kupferwasser Leon Iri; Yeaman Michael R; Nast Cynthia C; Kupferwasser Deborah; Xiong Yan-Qiong; Palma Marco; Cheung Ambrose L; Bayer Arnold S
Salicylic acid attenuates virulence in endovascular infections by targeting global regulatory pathways in Staphylococcus aureus.
The Journal of clinical investigation 2003;112(2):222-33.
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2003: Li Ronggui; Manna Adhar C; Dai Shaodong; Cheung Ambrose L; Zhang Gongyi
Crystal structure of the SarS protein from Staphylococcus aureus.
Journal of bacteriology 2003;185(14):4219-25.
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2003: Ingavale S S; Van Wamel W; Cheung A L
Characterization of RAT, an autolysis regulator in Staphylococcus aureus.
Molecular microbiology 2003;48(6):1451-66.
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2003: Manna Adhar C; Cheung Ambrose L
sarU, a sarA homolog, is repressed by SarT and regulates virulence genes in Staphylococcus aureus.
Infection and immunity 2003;71(1):343-53.
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2002: Xiong Yan-Qiong; Van Wamel William; Nast Cynthia C; Yeaman Michael R; Cheung Ambrose L; Bayer Arnold S
Activation and transcriptional interaction between agr RNAII and RNAIII in Staphylococcus aureus in vitro and in an experimental endocarditis model.
The Journal of infectious diseases 2002;186(5):668-77.
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2002: van Wamel Willem; Xiong Yan-Qiong; Bayer Arnold S; Yeaman Michael R; Nast Cynthia C; Cheung Ambrose L
Regulation of Staphylococcus aureus type 5 capsular polysaccharides by agr and sarA in vitro and in an experimental endocarditis model.
Microbial pathogenesis 2002;33(2):73-9.
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2002: Cheung Ambrose L; Zhang Gongyi
Global regulation of virulence determinants in Staphylococcus aureus by the SarA protein family.
Frontiers in bioscience : a journal and virtual library 2002;7():d1825-42.
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2001: Palma M; Cheung A L
sigma(B) activity in Staphylococcus aureus is controlled by RsbU and an additional factor(s) during bacterial growth.
Infection and immunity 2001;69(12):7858-65.
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2001: Bateman B T; Donegan N P; Jarry T M; Palma M; Cheung A L
Evaluation of a tetracycline-inducible promoter in Staphylococcus aureus in vitro and in vivo and its application in demonstrating the role of sigB in microcolony formation.
Infection and immunity 2001;69(12):7851-7.
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2001: Schmidt K A; Manna A C; Gill S; Cheung A L
SarT, a repressor of alpha-hemolysin in Staphylococcus aureus.
Infection and immunity 2001;69(8):4749-58.
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2001: Cheung A L; Schmidt K; Bateman B; Manna A C
SarS, a SarA homolog repressible by agr, is an activator of protein A synthesis in Staphylococcus aureus.
Infection and immunity 2001;69(4):2448-55.
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2001: Manna A; Cheung A L
Characterization of sarR, a modulator of sar expression in Staphylococcus aureus.
Infection and immunity 2001;69(2):885-96.
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2000: Kahl B C; Goulian M; van Wamel W; Herrmann M; Simon S M; Kaplan G; Peters G; Cheung A L
Staphylococcus aureus RN6390 replicates and induces apoptosis in a pulmonary epithelial cell line.
Infection and immunity 2000;68(9):5385-92.
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2000: Gresham H D; Lowrance J H; Caver T E; Wilson B S; Cheung A L; Lindberg F P
Survival of Staphylococcus aureus inside neutrophils contributes to infection.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(7):3713-22.
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1999: Chien Y; Manna A C; Projan S J; Cheung A L
SarA, a global regulator of virulence determinants in Staphylococcus aureus, binds to a conserved motif essential for sar-dependent gene regulation.
The Journal of biological chemistry 1999;274(52):37169-76.
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1999: Cheung A L; Chien Y T; Bayer A S
Hyperproduction of alpha-hemolysin in a sigB mutant is associated with elevated SarA expression in Staphylococcus aureus.
Infection and immunity 1999;67(3):1331-7.
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1998: Chien Y; Manna A C; Cheung A L
SarA level is a determinant of agr activation in Staphylococcus aureus.
Molecular microbiology 1998;30(5):991-1001.
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1998: Cheung A L; Nast C C; Bayer A S
Selective activation of sar promoters with the use of green fluorescent protein transcriptional fusions as the detection system in the rabbit endocarditis model.
Infection and immunity 1998;66(12):5988-93.
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1998: Manna A C; Bayer M G; Cheung A L
Transcriptional analysis of different promoters in the sar locus in Staphylococcus aureus.
Journal of bacteriology 1998;180(15):3828-36.
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1998: Gillaspy A F; Lee C Y; Sau S; Cheung A L; Smeltzer M S
Factors affecting the collagen binding capacity of Staphylococcus aureus.
Infection and immunity 1998;66(7):3170-8.
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1998: Fluckiger U; Wolz C; Cheung A L
Characterization of a sar homolog of Staphylococcus epidermidis.
Infection and immunity 1998;66(6):2871-8.
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1998: Chien Y; Cheung A L
Molecular interactions between two global regulators, sar and agr, in Staphylococcus aureus.
The Journal of biological chemistry 1998;273(5):2645-52.
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1997: Cheung A L; Bayer M G; Heinrichs J H
sar Genetic determinants necessary for transcription of RNAII and RNAIII in the agr locus of Staphylococcus aureus.
Journal of bacteriology 1997;179(12):3963-71.
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1997: Cheung A L; Eberhardt K; Heinrichs J H
Regulation of protein A synthesis by the sar and agr loci of Staphylococcus aureus.
Infection and immunity 1997;65(6):2243-9.
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1996: Sullam P M; Bayer A S; Foss W M; Cheung A L
Diminished platelet binding in vitro by Staphylococcus aureus is associated with reduced virulence in a rabbit model of infective endocarditis.
Infection and immunity 1996;64(12):4915-21.
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1996: Wolz C; McDevitt D; Foster T J; Cheung A L
Influence of agr on fibrinogen binding in Staphylococcus aureus Newman.
Infection and immunity 1996;64(8):3142-7.
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1996: Bayer M G; Heinrichs J H; Cheung A L
The molecular architecture of the sar locus in Staphylococcus aureus.
Journal of bacteriology 1996;178(15):4563-70.
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1996: Heinrichs J H; Bayer M G; Cheung A L
Characterization of the sar locus and its interaction with agr in Staphylococcus aureus.
Journal of bacteriology 1996;178(2):418-23.
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1995: Bayer A S; Sullam P M; Ramos M; Li C; Cheung A L; Yeaman M R
Staphylococcus aureus induces platelet aggregation via a fibrinogen-dependent mechanism which is independent of principal platelet glycoprotein IIb/IIIa fibrinogen-binding domains.
Infection and immunity 1995;63(9):3634-41.
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1995: Cheung A L; Wolz C; Yeaman M R; Bayer A S
Insertional inactivation of a chromosomal locus that modulates expression of potential virulence determinants in Staphylococcus aureus.
Journal of bacteriology 1995;177(11):3220-6.
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1994: Ren K; Bannan J D; Pancholi V; Cheung A L; Robbins J C; Fischetti V A; Zabriskie J B
Characterization and biological properties of a new staphylococcal exotoxin.
The Journal of experimental medicine 1994;180(5):1675-83.
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1994: Cheung A L; Eberhardt K J; Chung E; Yeaman M R; Sullam P M; Ramos M; Bayer A S
Diminished virulence of a sar-/agr- mutant of Staphylococcus aureus in the rabbit model of endocarditis.
The Journal of clinical investigation 1994;94(5):1815-22.
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1994: Cheung A L; Eberhardt K J; Fischetti V A
A method to isolate RNA from gram-positive bacteria and mycobacteria.
Analytical biochemistry 1994;222(2):511-4.
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1994: Cheung A L; Projan S J
Cloning and sequencing of sarA of Staphylococcus aureus, a gene required for the expression of agr.
Journal of bacteriology 1994;176(13):4168-72.
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1994: Cheung A L; Yeaman M R; Sullam P M; Witt M D; Bayer A S
Role of the sar locus of Staphylococcus aureus in induction of endocarditis in rabbits.
Infection and immunity 1994;62(5):1719-25.
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1994: Cheung A L; Ying P
Regulation of alpha- and beta-hemolysins by the sar locus of Staphylococcus aureus.
Journal of bacteriology 1994;176(3):580-5.
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1992: Cheung A L; Koomey J M; Butler C A; Projan S J; Fischetti V A
Regulation of exoprotein expression in Staphylococcus aureus by a locus (sar) distinct from agr.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(14):6462-6.
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1991: Cheung A L; Koomey J M; Lee S; Jaffe E A; Fischetti V A
Recombinant human tumor necrosis factor alpha promotes adherence of Staphylococcus aureus to cultured human endothelial cells.
Infection and immunity 1991;59(10):3827-31.
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1991: Cheung A L; Krishnan M; Jaffe E A; Fischetti V A
Fibrinogen acts as a bridging molecule in the adherence of Staphylococcus aureus to cultured human endothelial cells.
The Journal of clinical investigation 1991;87(6):2236-45.
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1991: Cheung A L; Fischetti V A
The role of fibrinogen in mediating staphylococcal adherence to fibers.
The Journal of surgical research 1991;50(2):150-5.
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1991: Cheung A L; Ying P; Fischetti V A
A method to detect proteinase activity using unprocessed X-ray films.
Analytical biochemistry 1991;193(1):20-3.
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1990: Cheung A L; Fischetti V A
The role of fibrinogen in staphylococcal adherence to catheters in vitro.
The Journal of infectious diseases 1990;161(6):1177-86.
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1989: Cheung A L; Fischetti V A
Role of surface proteins in staphylococcal adherence to fibers in vitro.
The Journal of clinical investigation 1989;83(6):2041-9.
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1988: Cheung A L; Fischetti V A
Variation in the expression of cell wall proteins of Staphylococcus aureus grown on solid and liquid media.
Infection and immunity 1988;56(5):1061-5.
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