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Nan Chiang

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Jesmond Dalli; Nicos A Petasis; Jeremy W Winkler; Hildur Arnardottir; Chien-Yee C Cheng; Nan Chiang; Romain A Colas; Charles N Serhan
Resolvin D3 and aspirin-triggered resolvin D3 are potent immunoresolvents.
Li Gao; Nan Chiang; Dan Faibish; Gabrielle Fredman; Bruno S Herrera; Charles N Serhan; Thomas E Van Dyke; Robert Gyurko
Resolvin E1 and chemokine-like receptor 1 mediate bone preservation.
Sriram Krishnamoorthy; Antonio Recchiuti; Nan Chiang; Gabrielle Fredman; Charles N Serhan
Resolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs.

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All Publications

2013: Jesmond Dalli; Nicos A Petasis; Jeremy W Winkler; Hildur Arnardottir; Chien-Yee C Cheng; Nan Chiang; Romain A Colas; Charles N Serhan
Resolvin D3 and aspirin-triggered resolvin D3 are potent immunoresolvents.
Chemistry & biology 2013;20(2):188-201.
2013: Li Gao; Nan Chiang; Dan Faibish; Gabrielle Fredman; Bruno S Herrera; Charles N Serhan; Thomas E Van Dyke; Robert Gyurko
Resolvin E1 and chemokine-like receptor 1 mediate bone preservation.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(2):689-94.
2012: Sriram Krishnamoorthy; Antonio Recchiuti; Nan Chiang; Gabrielle Fredman; Charles N Serhan
Resolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs.
The American journal of pathology 2012;180(5):2018-27.
2012: Nan Chiang; Gabrielle Fredman; Sungwhan F Oh; Birgitta A Schmidt; Fredrik Bäckhed; Thad Vickery; Charles N Serhan
Infection regulates pro-resolving mediators that lower antibiotic requirements.
Nature 2012;484(7395):524-8.
2011: Rong Yang; Nan Chiang; Sungwhan F Oh; Charles N Serhan
Metabolomics-lipidomics of eicosanoids and docosanoids generated by phagocytes.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2011;Chapter 14():Unit 14.26.
2011: Charles N Serhan; Sriram Krishnamoorthy; Antonio Recchiuti; Nan Chiang
Novel anti-inflammatory--pro-resolving mediators and their receptors.
Current topics in medicinal chemistry 2011;11(6):629-47.
2010: Sriram Krishnamoorthy; Antonio Recchiuti; Nan Chiang; Stephanie Yacoubian; Chih-Hao Lee; Rong Yang; Nicos A Petasis; Charles N Serhan
Resolvin D1 binds human phagocytes with evidence for proresolving receptors.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(4):1660-5.
2009: Yiping Jin; Makoto Arita; Qiang Zhang; Daniel R Saban; Sunil K Chauhan; Nan Chiang; Charles N Serhan; Reza Dana
Anti-angiogenesis effect of the novel anti-inflammatory and pro-resolving lipid mediators.
Investigative ophthalmology & visual science 2009;50(10):4743-52.
2008: Maria Dona; Gabrielle Fredman; Jan M Schwab; Nan Chiang; Makoto Arita; Ahmad Goodarzi; Guiying Cheng; Ulrich H von Andrian; Charles N Serhan
Resolvin E1, an EPA-derived mediator in whole blood, selectively counterregulates leukocytes and platelets.
Blood 2008;112(3):848-55.
2008: Charles N Serhan; Nan Chiang; Thomas E Van Dyke
Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators.
Nature reviews. Immunology 2008;8(5):349-61.
2008: Charles N Serhan; Nan Chiang
Endogenous pro-resolving and anti-inflammatory lipid mediators: a new pharmacologic genus.
British journal of pharmacology 2008;153 Suppl 1():S200-15.
2008: Nan Chiang; Jan M Schwab; Gabrielle Fredman; Kie Kasuga; Simon Gelman; Charles N Serhan
Anesthetics impact the resolution of inflammation.
PloS one 2008;3(4):e1879.
2007: Jan M Schwab; Nan Chiang; Makoto Arita; Charles N Serhan
Resolvin E1 and protectin D1 activate inflammation-resolution programmes.
Nature 2007;447(7146):869-74.
2007: Makoto Arita; Taisuke Ohira; Yee-Ping Sun; Siva Elangovan; Nan Chiang; Charles N Serhan
Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(6):3912-7.
2006: Nan Chiang; Charles N Serhan; Sven-Erik Dahlén; Jeffrey M Drazen; Douglas W P Hay; G Enrico Rovati; Takao Shimizu; Takehiko Yokomizo; Charles Brink
The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo.
Pharmacological reviews 2006;58(3):463-87.
2006: Hatice Hasturk; Alpdogan Kantarci; Taisuke Ohira; M Arita; N Ebrahimi; Nan Chiang; Nicos A Petasis; Bruce D Levy; Charles N Serhan; Thomas E Van Dyke
RvE1 protects from local inflammation and osteoclast- mediated bone destruction in periodontitis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(2):401-3.
2006: Nan Chiang; Shelley Hurwitz; Paul M Ridker; Charles N Serhan
Aspirin has a gender-dependent impact on antiinflammatory 15-epi-lipoxin A4 formation: a randomized human trial.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(2):e14-7.
2005: Gerard Bannenberg; Nan Chiang; Amiram Ariel; Makoto Arita; Eric Tjonahen; Katherine Gotlinger; Song Hong; Charles N Serhan
Molecular circuits of resolution: formation and actions of resolvins and protectins.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(7):4345-55.
2005: Makoto Arita; Francesca Bianchini; Julio Aliberti; Alan Sher; Nan Chiang; Song Hong; Rong Yang; Nicos A Petasis; Charles N Serhan
Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1.
The Journal of experimental medicine 2005;201(5):713-22.
2004: Nan Chiang; Charles N Serhan
Aspirin triggers formation of anti-inflammatory mediators: New mechanism for an old drug.
Discovery medicine 2004;4(24):470-5.
2004: Nan Chiang; Edmund A Bermudez; Paul M Ridker; Shelley Hurwitz; Charles N Serhan
Aspirin triggers antiinflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(42):15178-83.
2003: Victor L Marcheselli; Song Hong; Walter J Lukiw; Xiao Hua Tian; Karsten Gronert; Alberto Musto; Mattie Hardy; Juan M Gimenez; Nan Chiang; Charles N Serhan; Nicolas G Bazan
Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression.
The Journal of biological chemistry 2003;278(44):43807-17.
2003: Amiram Ariel; Nan Chiang; Makoto Arita; Nicos A Petasis; Charles N Serhan
Aspirin-triggered lipoxin A4 and B4 analogs block extracellular signal-regulated kinase-dependent TNF-alpha secretion from human T cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(12):6266-72.
2003: Nan Chiang; Tomoko Takano; Makoto Arita; Shiro Watanabe; Charles N Serhan
A novel rat lipoxin A4 receptor that is conserved in structure and function.
British journal of pharmacology 2003;139(1):89-98.
2002: Mauro Perretti; Nan Chiang; Mylinh La; Iolanda M Fierro; Stefano Marullo; Stephen J Getting; Egle Solito; Charles N Serhan
Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor.
Nature medicine 2002;8(11):1296-302.
2002: Charles N Serhan; Nan Chiang
Lipid-derived mediators in endogenous anti-inflammation and resolution: lipoxins and aspirin-triggered 15-epi-lipoxins.
TheScientificWorldJournal 2002;2():169-204.
2001: Charles N Serhan; Iolanda M Fierro; Nan Chiang; M Pouliot
Cutting edge: nociceptin stimulates neutrophil chemotaxis and recruitment: inhibition by aspirin-triggered-15-epi-lipoxin A4.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(6):3650-4.
2001: Karsten Gronert; T Martinsson-Niskanen; S Ravasi; Nan Chiang; Charles N Serhan
Selectivity of recombinant human leukotriene D(4), leukotriene B(4), and lipoxin A(4) receptors with aspirin-triggered 15-epi-LXA(4) and regulation of vascular and inflammatory responses.
The American journal of pathology 2001;158(1):3-9.
2000: Charles N Serhan; Clary B Clish; J Brannon; Sean P Colgan; Karsten Gronert; Nan Chiang
Anti-microinflammatory lipid signals generated from dietary N-3 fatty acids via cyclooxygenase-2 and transcellular processing: a novel mechanism for NSAID and N-3 PUFA therapeutic actions.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2000;51(4 Pt 1):643-54.
2000: Charles N Serhan; Clary B Clish; J Brannon; Sean P Colgan; Nan Chiang; Karsten Gronert
Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing.
The Journal of experimental medicine 2000;192(8):1197-204.
2000: Clary B Clish; Bruce D Levy; Nan Chiang; Hsin-Hsiung Tai; Charles N Serhan
Oxidoreductases in lipoxin A4 metabolic inactivation: a novel role for 15-onoprostaglandin 13-reductase/leukotriene B4 12-hydroxydehydrogenase in inflammation.
The Journal of biological chemistry 2000;275(33):25372-80.
2000: Marek Sanak; Bruce D Levy; Clary B Clish; Nan Chiang; Karsten Gronert; Lucyna Mastalerz; Charles N Serhan; Andrew Szczeklik
Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2000;16(1):44-9.
2000: Nan Chiang; Iolanda M Fierro; Karsten Gronert; Charles N Serhan
Activation of lipoxin A(4) receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation.
The Journal of experimental medicine 2000;191(7):1197-208.
2000: Charles N Serhan; Tomoko Takano; Nan Chiang; Karsten Gronert; Clary B Clish
Formation of endogenous "antiinflammatory" lipid mediators by transcellular biosynthesis. Lipoxins and aspirin-triggered lipoxins inhibit neutrophil recruitment and vascular permeability.
American journal of respiratory and critical care medicine 2000;161(2 Pt 2):S95-S101.
2000: Charles N Serhan; Bruce D Levy; Clary B Clish; Karsten Gronert; Nan Chiang
Lipoxins, aspirin-triggered 15-epi-lipoxin stable analogs and their receptors in anti-inflammation: a window for therapeutic opportunity.
Ernst Schering Research Foundation workshop 2000;(31):143-85.
1999: Nan Chiang; Karsten Gronert; Clary B Clish; J A O'Brien; Mason W Freeman; Charles N Serhan
Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion.
The Journal of clinical investigation 1999;104(3):309-16.
1999: Charles N Serhan; Tomoko Takano; Karsten Gronert; Nan Chiang; Clary B Clish
Lipoxin and aspirin-triggered 15-epi-lipoxin cellular interactions anti-inflammatory lipid mediators.
Clinical chemistry and laboratory medicine : CCLM / FESCC 1999;37(3):299-309.
1998: Nan Chiang; Tomoko Takano; Clary B Clish; Nicos A Petasis; Hsin-Hsiung Tai; Charles N Serhan
Aspirin-triggered 15-epi-lipoxin A4 (ATL) generation by human leukocytes and murine peritonitis exudates: development of a specific 15-epi-LXA4 ELISA.
The Journal of pharmacology and experimental therapeutics 1998;287(2):779-90.
1998: Nan Chiang; Hsin-Hsiung Tai
The role of N-glycosylation of human thromboxane A2 receptor in ligand binding.
Archives of biochemistry and biophysics 1998;352(2):207-13.
1997: MF Taylor; M Wang; AK Bhattacharyya; Nan Chiang; Hsin-Hsiung Tai; Delwood C Collins
Expression of rat steroid 5 alpha-reductase (isozyme-1) in Spodoptera frugiperda, SF21, insect cells: expression of rat steroid 5 alpha-reductase.
Steroids 1997;62(4):373-8.
1997: Hsin-Hsiung Tai; C Huang; Nan Chiang
Structure and function of prostanoid receptors as revealed by site-directed mutagenesis.
Advances in experimental medicine and biology 1997;407():205-9.
1996: Nan Chiang; W M Kan; Hsin-Hsiung Tai
Site-directed mutagenesis of cysteinyl and serine residues of human thromboxane A2 receptor in insect cells.
Archives of biochemistry and biophysics 1996;334(1):9-17.