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Yi-Ming Chiang

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Chun-Jun Guo; James F Sanchez; Kenneth S Bruno; Shu-Ling Chang; Yi-Ming Chiang; Hsu-Hua Yeh; Clay C C Wang
Biosynthetic Pathway for the Epipolythiodioxopiperazine Acetylaranotin in Aspergillus terreus Revealed by Genome-Based Deletion Analysis.
Shu-Lin Chang; Yi-Ming Chiang; Tung-Kung Wu; Hsu-Hua Yeh; Clay C C Wang
Reconstitution of the early steps of gliotoxin biosynthesis in Aspergillus nidulans reveals the role of the monooxygenase GliC.
Hsu-Hua Yeh; Tung-Kung Wu; Kenneth S Bruno; Shu-Lin Chang; Yi-Ming Chiang; Berl R Oakley; Clay C C Wang
Engineering fungal nonreducing polyketide synthase by heterologous expression and domain swapping.

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All Publications

2013: Chun-Jun Guo; James F Sanchez; Kenneth S Bruno; Shu-Ling Chang; Yi-Ming Chiang; Hsu-Hua Yeh; Clay C C Wang
Biosynthetic Pathway for the Epipolythiodioxopiperazine Acetylaranotin in Aspergillus terreus Revealed by Genome-Based Deletion Analysis.
Journal of the American Chemical Society 2013;135(19):7205-13.
2013: Shu-Lin Chang; Yi-Ming Chiang; Tung-Kung Wu; Hsu-Hua Yeh; Clay C C Wang
Reconstitution of the early steps of gliotoxin biosynthesis in Aspergillus nidulans reveals the role of the monooxygenase GliC.
Bioorganic & medicinal chemistry letters 2013;23(7):2155-7.
2013: Hsu-Hua Yeh; Tung-Kung Wu; Kenneth S Bruno; Shu-Lin Chang; Yi-Ming Chiang; Berl R Oakley; Clay C C Wang
Engineering fungal nonreducing polyketide synthase by heterologous expression and domain swapping.
Organic letters 2013;15(4):756-9.
2012: Chun-Jun Guo; Benjamin P Knox; Kuan-Han Lee; Hsien-Chun Lo; Berl R Oakley; James F Sanchez; Kenneth S Bruno; Yi-Ming Chiang; Clay C C Wang
Molecular genetic characterization of a cluster in A. terreus for biosynthesis of the meroterpenoid terretonin.
Organic letters 2012;14(22):5684-7.
2012: Hsu-Hua Yeh; Tung-Kung Wu; Manmeet Ahuja; Kenneth S Bruno; Yi-Ming Chiang; Ruth Entwistle; Kuan-Han Lee; Berl R Oakley; Clay C C Wang
Molecular genetic analysis reveals that a nonribosomal peptide synthetase-like (NRPS-like) gene in Aspergillus nidulans is responsible for microperfuranone biosynthesis.
Applied microbiology and biotechnology 2012;96(3):739-48.
2007: Shu-Lin Chang; Yi-Ming Chiang; Cicero Lee-Tian Chang; Hsu-Hua Yeh; Lie-Fen Shyur; Yueh-Hsiung Kuo; Tung-Kung Wu; Wen-Chin Yang
Flavonoids, centaurein and centaureidin, from Bidens pilosa, stimulate IFN-gamma expression.
Journal of ethnopharmacology 2007;112(2):232-6.
2007: Li-Wha Wu; Yi-Ming Chiang; Hsiao-Ching Chuang; Chiu-Ping Lo; Kai-Ying Yang; Sheng-Yang Wang; Lie-Fen Shyur
A novel polyacetylene significantly inhibits angiogenesis and promotes apoptosis in human endothelial cells through activation of the CDK inhibitors and caspase-7.
Planta medica 2007;73(7):655-61.
2007: Cicero Lee-Tian Chang; Shu-Lin Chang; Yi-Mei Lee; Yi-Ming Chiang; Da-Yung Chuang; Hui-Kai Kuo; Wen-Chin Yang
Cytopiloyne, a polyacetylenic glucoside, prevents type 1 diabetes in nonobese diabetic mice.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(11):6984-93.
2007: Yi-Ming Chiang; Cicero Lee-Tian Chang; Shu-Lin Chang; Wen-Chin Yang; Lie-Fen Shyur
Cytopiloyne, a novel polyacetylenic glucoside from Bidens pilosa, functions as a T helper cell modulator.
Journal of ethnopharmacology 2007;110(3):532-8.
2007: Shu-Lin Chang; Hsu-Hua Yeh; Yu-Shiun Lin; Yi-Ming Chiang; Tung-Kung Wu; Wen-Chin Yang
The effect of centaurein on interferon-gamma expression and Listeria infection in mice.
Toxicology and applied pharmacology 2007;219(1):54-61.
2005: Yi-Ming Chiang; Chiu-Ping Lo; Yi-Ping Chen; Sheng-Yang Wang; Ning-Sun Yang; Yueh-Hsiung Kuo; Lie-Fen Shyur
Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin.
British journal of pharmacology 2005;146(3):352-63.
2005: Yi-Ming Chiang; Jang-Yang Chang; Ching-Chuan Kuo; Chi-Yen Chang; Yueh-Hsiung Kuo
Cytotoxic triterpenes from the aerial roots of Ficus microcarpa.
Phytochemistry 2005;66(4):495-501.
2005: Cicero Lee-Tian Chang; Hui-Kai Kuo; Shu-Lin Chang; Yi-Ming Chiang; Tsung-Han Lee; Wen-Mein Wu; Lie-Fen Shyur; Wen-Chin Yang
The distinct effects of a butanol fraction of Bidens pilosa plant extract on the development of Th1-mediated diabetes and Th2-mediated airway inflammation in mice.
Journal of biomedical science 2005;12(1):79-89.
2004: Yi-Ming Chiang; Da-Yung Chuang; Sheng-Yang Wang; Yueh-Hsiung Kuo; Pi-Wen Tsai; Lie-Fen Shyur
Metabolite profiling and chemopreventive bioactivity of plant extracts from Bidens pilosa.
Journal of ethnopharmacology 2004;95(2-3):409-19.
2004: Li-Wha Wu; Yi-Ming Chiang; Hsiao-Ching Chuang; Sheng-Yang Wang; Ga-Wen Yang; Ya-Huey Chen; Ling-Ya Lai; Lie-Fen Shyur
Polyacetylenes function as anti-angiogenic agents.
Pharmaceutical research 2004;21(11):2112-9.
2004: Shu-Lin Chang; Cicero Lee-Tian Chang; Yi-Ming Chiang; Rong-Hong Hsieh; Chii-Ruey Tzeng; Tung-Kung Wu; Huey-Kang Sytwu; Lie-Fen Shyur; Wen-Chin Yang
Polyacetylenic compounds and butanol fraction from Bidens pilosa can modulate the differentiation of helper T cells and prevent autoimmune diabetes in non-obese diabetic mice.
Planta medica 2004;70(11):1045-51.