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Kazuo Chihara

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Taiki Maki; Shiho Nakanishi; Yutaka Takahashi; Daisuke Yamamoto; Kazuo Chihara; Genzo Iguchi; Keiji Iida; Hidesuke Kaji; Yasuhiko Okimura
Branched-chain amino acids reduce hindlimb suspension-induced muscle atrophy and protein levels of atrogin-1 and MuRF1 in rats.
Kenji Sekiguchi; Fumio Kanda; Nobuo Kohara; Shigeru Mitsui; Kazuo Chihara
Fibrillation potentials of denervated rat skeletal muscle are associated with expression of cardiac-type voltage-gated sodium channel isoform Nav1.5.
Hitoshi Nishizawa; Yasuhiko Okimura; Yasushi Seo; Kentaro Suda; Michiko Takahashi; Masaaki Yamamoto; Yoshihiko Yano; Kazuo Chihara; Hidenori Fukuoka; Yoshitake Hayashi; Genzo Iguchi; Hidesuke Kaji; Riko Kitazawa; Sohei Kitazawa; Masafumi Koga; Ayumi Murawaki; Yutaka Takahashi
Nonalcoholic fatty liver disease in adult hypopituitary patients with GH deficiency and the impact of GH replacement therapy.

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2012: Taiki Maki; Shiho Nakanishi; Yutaka Takahashi; Daisuke Yamamoto; Kazuo Chihara; Genzo Iguchi; Keiji Iida; Hidesuke Kaji; Yasuhiko Okimura
Branched-chain amino acids reduce hindlimb suspension-induced muscle atrophy and protein levels of atrogin-1 and MuRF1 in rats.
Nutrition research (New York, N.Y.) 2012;32(9):676-83.
2012: Kenji Sekiguchi; Fumio Kanda; Nobuo Kohara; Shigeru Mitsui; Kazuo Chihara
Fibrillation potentials of denervated rat skeletal muscle are associated with expression of cardiac-type voltage-gated sodium channel isoform Nav1.5.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 2012;123(8):1650-5.
2012: Hitoshi Nishizawa; Yasuhiko Okimura; Yasushi Seo; Kentaro Suda; Michiko Takahashi; Masaaki Yamamoto; Yoshihiko Yano; Kazuo Chihara; Hidenori Fukuoka; Yoshitake Hayashi; Genzo Iguchi; Hidesuke Kaji; Riko Kitazawa; Sohei Kitazawa; Masafumi Koga; Ayumi Murawaki; Yutaka Takahashi
Nonalcoholic fatty liver disease in adult hypopituitary patients with GH deficiency and the impact of GH replacement therapy.
European journal of endocrinology / European Federation of Endocrine Societies 2012;167(1):67-74.
2011: Anastasia-Evi Handayaningsih; Genzo Iguchi; Hidenori Fukuoka; Hitoshi Nishizawa; Michiko Takahashi; Masaaki Yamamoto; Elizabeth-Henny Herningtyas; Yasuhiko Okimura; Hidesuke Kaji; Kazuo Chihara; Susumu Seino; Yutaka Takahashi
Reactive oxygen species play an essential role in IGF-I signaling and IGF-I-induced myocyte hypertrophy in C2C12 myocytes.
Endocrinology 2011;152(3):912-21.
2011: Masaaki Yamamoto; Genzo Iguchi; Ryoko Takeno; Yasuhiko Okimura; Toshiaki Sano; Michiko Takahashi; Hitoshi Nishizawa; Anastasia Evi Handayaningshi; Hidenori Fukuoka; Maya Tobita; Takatoshi Saitoh; Katsuyoshi Tojo; Atsuko Mokubo; Akio Morinobu; Keiji Iida; Hidesuke Kaji; Susumu Seino; Kazuo Chihara; Yutaka Takahashi
Adult combined GH, prolactin, and TSH deficiency associated with circulating PIT-1 antibody in humans.
The Journal of clinical investigation 2011;121(1):113-9.
2010: Hiromi Shibahara; Nobuko Ikeshita; Yuka Sugiyama; Keizo Toda; Daisuke Yamamoto; Elizabeth Henny Herningtyas; Taiki Maki; Eriko Kubota; Genzo Iguchi; Keiji Iida; Yutaka Takahashi; Hidesuke Kaji; Kazuo Chihara; Yasuhiko Okimura
W194XProp1 and S156insTProp1, both of which have intact DNA-binding domain, show a different DNA-binding activity to the Prop1-binding element in human Pit-1 gene.
Molecular and cellular endocrinology 2010;323(2):167-71.
2010: Hidenori Fukuoka; Keiji Iida; Hitoshi Nishizawa; Mari Imanaka; Ryoko Takeno; Genzo Iguchi; Michiko Takahashi; Yasuhiko Okimura; Hidesuke Kaji; Kazuo Chihara; Yutaka Takahashi
IGF-I stimulates reactive oxygen species (ROS) production and inhibits insulin-dependent glucose uptake via ROS in 3T3-L1 adipocytes.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2010;20(3):212-9.
2010: Kazuo Chihara; Kenji Fujieda; Akira Shimatsu; Takami Miki; Katsuhiko Tachibana
Dose-dependent changes in body composition during growth hormone (GH) treatment in Japanese patients with adult GH deficiency: a randomized, placebo-controlled trial.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2010;20(3):205-11.
2010: Daisuke Yamamoto; Taiki Maki; Elizabeth Henny Herningtyas; Nobuko Ikeshita; Hiromi Shibahara; Yuka Sugiyama; Shiho Nakanishi; Keiji Iida; Genzo Iguchi; Yutaka Takahashi; Hidesuke Kaji; Kazuo Chihara; Yasuhiko Okimura
Branched-chain amino acids protect against dexamethasone-induced soleus muscle atrophy in rats.
Muscle & nerve 2010;41(6):819-27.
2009: Yoshifumi Inoue; Lucie Canaff; Geoffrey N Hendy; Itoko Hisa; Toshitsugu Sugimoto; Kazuo Chihara; Hiroshi Kaji
Role of Smad3, acting independently of transforming growth factor-beta, in the early induction of Wnt-beta-catenin signaling by parathyroid hormone in mouse osteoblastic cells.
Journal of cellular biochemistry 2009;108(1):285-94.
2009: Keiji Iida; Yutaka Takahashi; Hidesuke Kaji; Yasuhiko Okimura; O Nose; Kazuo Chihara
Difference between Japanese and Caucasian populations in the allelic frequency of growth hormone receptor polymorphisms.
Journal of pediatric endocrinology & metabolism : JPEM 2009;22(1):41-6.
2008: Nobuko Ikeshita; Mayuko Kawagishi; Hiromi Shibahara; Keizo Toda; Tomoe Yamashita; Daisuke Yamamoto; Yuka Sugiyama; Genzo Iguchi; Keiji Iida; Yutaka Takahashi; Hidesuke Kaji; Kazuo Chihara; Yasuhiko Okimura
Identification and analysis of prophet of Pit-1-binding sites in human Pit-1 gene.
Endocrinology 2008;149(11):5491-9.
2008: Hiroshi Kaji; Junko Naito; Yoshihisa Inoue; Hideaki Sowa; Toshitsugu Sugimoto; Kazuo Chihara
Statin suppresses apoptosis in osteoblastic cells: role of transforming growth factor-beta-Smad3 pathway.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2008;40(11):746-51.
2008: Elizabeth Henny Herningtyas; Yasuhiko Okimura; Anastasia Evi Handayaningsih; Daisuke Yamamoto; Taiki Maki; Keiji Iida; Yutaka Takahashi; Hidesuke Kaji; Kazuo Chihara
Branched-chain amino acids and arginine suppress MaFbx/atrogin-1 mRNA expression via mTOR pathway in C2C12 cell line.
Biochimica et biophysica acta 2008;1780(10):1115-20.
2008: Kazuo Chihara; Yuzuru Kato; Akira Shimatsu; Toshiaki Tanaka; Hitoshi Kohno
Efficacy and safety of individualized growth hormone treatment in adult Japanese patients with growth hormone deficiency.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2008;18(5):394-403.
2008: Kazuo Chihara; Yuzuru Kato; Hitoshi Kohno; Koji Takano; Toshiaki Tanaka; Akira Teramoto; Akira Shimatsu
Safety and efficacy of growth hormone (GH) during extended treatment of adult Japanese patients with GH deficiency (GHD).
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2008;18(4):307-17.
2008: Yutaka Takahashi; Keiji Iida; Ryoko Takeno; Riko Kitazawa; Sohei Kitazawa; Hidetsuna Kitamura; Yoshio Fujioka; Hiroyuki Yamada; Fumio Kanda; Shigeo Ohta; Kiyomi Nishimaki; Masayo Fujimoto; Takeshi Kondo; Genzo Iguchi; Kentaro Takahashi; Hidesuke Kaji; Yasuhiko Okimura; Kazuo Chihara
Hepatic failure and enhanced oxidative stress in mitochondrial diabetes.
Endocrine journal 2008;55(3):509-14.
2008: Keiji Iida; Kandai Nozu; Yutaka Takahashi; Yasuhiko Okimura; Hidesuke Kaji; Masafumi Matsuo; Kazuo Chihara
Characterization of a splicing abnormality in Gitelman syndrome.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2008;51(6):1077-8.
2008: Michiko Takahashi; Yutaka Takahashi; Kenichi Takahashi; Fyodor N Zolotaryov; Kyoung Su Hong; Riko Kitazawa; Keiji Iida; Yasuhiko Okimura; Hidesuke Kaji; Sohei Kitazawa; Masato Kasuga; Kazuo Chihara
Chemerin enhances insulin signaling and potentiates insulin-stimulated glucose uptake in 3T3-L1 adipocytes.
FEBS letters 2008;582(5):573-8.
2008: Hiroshi Kaji; Mika Yamauchi; Kazuo Chihara; Toshitsugu Sugimoto
Glucocorticoid excess affects cortical bone geometry in premenopausal, but not postmenopausal, women.
Calcified tissue international 2008;82(3):182-90.
2008: Takashi Yamane; Akira Hashiramoto; Yasushi Tanaka; Ken Tsumiyama; Yasushi Miura; Kazuko Shiozawa; Kazuo Chihara; Shunichi Shiozawa
Easy and accurate diagnosis of rheumatoid arthritis using anti-cyclic citrullinated peptide 2 antibody, swollen joint count, and C-reactive protein/rheumatoid factor.
The Journal of rheumatology 2008;35(3):414-20.
2008: Yoshifumi Inoue; Hiroshi Kaji; Itoko Hisa; Takako Tobimatsu; Junko Naito; Mei-Fway Iu; Toshitsugu Sugimoto; Kazuo Chihara
Vitamin D status affects osteopenia in postmenopausal patients with primary hyperparathyroidism.
Endocrine journal 2008;55(1):57-65.
2008: Daisuke Yamamoto; Nobuko Ikeshita; Takako Matsubara; Hiromitsu Tasaki; Elizabeth Henny Herningtyas; Keizo Toda; Keiji Iida; Yutaka Takahashi; Hidesuke Kaji; Kazuo Chihara; Yasuhiko Okimura
GHRP-2, a GHS-R agonist, directly acts on myocytes to attenuate the dexamethasone-induced expressions of muscle-specific ubiquitin ligases, Atrogin-1 and MuRF1.
Life sciences 2008;82(9-10):460-6.
2008: Keizo Toda; Daisuke Yamamoto; Mariko Fumoto; Nobuko Ikeshita; Elizabeth Henny Herningtyas; Keiji Iida; Yutaka Takahashi; Hiroshi Kaji; Kazuo Chihara; Yasuhiko Okimura
Involvement of mPOU (Brn-5), a class VI POU protein, in the gene expression of Pit-1 as well as PRL.
Molecular and cellular endocrinology 2008;280(1-2):20-9.
2008: Mari Imanaka; Keiji Iida; Ayumi Murawaki; Hitoshi Nishizawa; Hidenori Fukuoka; Ryoko Takeno; Yutaka Takahashi; Yasuhiko Okimura; Hidesuke Kaji; Kazuo Chihara
Growth hormone stimulates mechano growth factor expression and activates myoblast transformation in C2C12 cells.
The Kobe journal of medical sciences 2008;54(1):E46-54.
2008: Hidenori Fukuoka; Yutaka Takahashi; Keiji Iida; Takumi Kudo; Hitoshi Nishizawa; Mari Imanaka; Ryoko Takeno; Genzo Iguchi; Kentaro Takahashi; Yasuhiko Okimura; Hidesuke Kaji; Kazuo Chihara
Low serum IGF-I/GH ratio is associated with abnormal glucose tolerance in acromegaly.
Hormone research 2008;69(3):165-71.
2008: Hiroshi Kaji; Mika Yamauchi; Kazuo Chihara; Toshitsugu Sugimoto
Relationship between endogenous parathyroid hormone and bone metabolism/geometry in female patients treated with glucocorticoid.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2008;40(1):60-5.
2007: Michiko Takahashi; Yutaka Takahashi; Kenichi Takahashi; Fyodor N Zolotaryov; Kyoung Su Hong; Keiji Iida; Yasuhiko Okimura; Hiroshi Kaji; Kazuo Chihara
CXCL14 enhances insulin-dependent glucose uptake in adipocytes and is related to high-fat diet-induced obesity.
Biochemical and biophysical research communications 2007;364(4):1037-42.
2007: Kazuo Chihara; Akira Shimatsu; Naomi Hizuka; Toshiaki Tanaka; Yoshiki Seino; Yuzuru Katofor
A simple diagnostic test using GH-releasing peptide-2 in adult GH deficiency.
European journal of endocrinology / European Federation of Endocrine Societies 2007;157(1):19-27.
2007: Yutaka Takahashi; Keiji Iida; Kentaro Takahashi; Shiro Yoshioka; Hidenori Fukuoka; Ryoko Takeno; Mari Imanaka; Hitoshi Nishizawa; Michiko Takahashi; Yasushi Seo; Yoshitake Hayashi; Takuma Kondo; Yasuhiko Okimura; Hiroshi Kaji; Riko Kitazawa; Sohei Kitazawa; Kazuo Chihara
Growth hormone reverses nonalcoholic steatohepatitis in a patient with adult growth hormone deficiency.
Gastroenterology 2007;132(3):938-43.
2007: Daisuke Yamamoto; Nobuko Ikeshita; Rie Daito; Elizabeth Henny Herningtyas; Keizo Toda; Kentaro Takahashi; Keiji Iida; Yutaka Takahashi; Hiroshi Kaji; Kazuo Chihara; Yasuhiko Okimura
Neither intravenous nor intracerebroventricular administration of obestatin affects the secretion of GH, PRL, TSH and ACTH in rats.
Regulatory peptides 2007;138(2-3):141-4.
2007: Mari Imanaka; Keiji Iida; Hitoshi Nishizawa; Hidenori Fukuoka; Ryoko Takeno; Kentaro Takahashi; Hiroshi Kaji; Yutaka Takahashi; Yasuhiko Okimura; Hiroshi Kaji; Yasuo Imanishi; Kazuo Chihara
McCune-Albright syndrome with acromegaly and fibrous dysplasia associated with the GNAS gene mutation identified by sensitive PNA-clamping method.
Internal medicine (Tokyo, Japan) 2007;46(18):1577-83.
2006: Mari Imanaka; Keiji Iida; Kentaro Takahashi; Kazuo Tsuji; Hitoshi Nishizawa; Hidenori Fukuoka; Ryoko Takeno; Yutaka Takahashi; Yasuhiko Okimura; Hiroshi Kaji; Kazuo Chihara
The N131S mutation in the von Hippel-Lindau gene in a Japanese family with pheochromocytoma and hemangioblastomas.
Endocrine journal 2006;53(6):819-27.
2006: Kazuo Chihara; Akira Shimatsu; Yuzuru Kato; Hitoshi Kohno; Toshiaki Tanaka; Kazue Takano; Minoru Irie
Growth hormone (GH) effects on central fat accumulation in adult Japanese GH deficient patients: 6-month fixed-dose effects persist during second 6-month individualized-dose phase.
Endocrine journal 2006;53(6):853-8.
2006: Hiroshi Kaji; Junko Naito; Hideaki Sowa; Toshitsugu Sugimoto; Kazuo Chihara
Serum soluble factors induce the proliferation, alkaline phosphatase activity and transforming growth factor-beta signal in osteoblastic cells in the patient with hepatitis C-associated osteosclerosis.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2006;114(10):599-604.
2006: Hiroshi Kaji; Junko Naito; Hideaki Sowa; Toshitsugu Sugimoto; Kazuo Chihara
Smad3 differently affects osteoblast differentiation depending upon its differentiation stage.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2006;38(11):740-5.
2006: Yasuhiko Okimura; Kazuo Chihara
[Diagnosis and therapy for pituitary tumors].
No shinkei geka. Neurological surgery 2006;34(11):1083-92.
2006: Kazuo Chihara; Yuzuru Kato; Kazue Takano; Akira Shimatsu; Hitoshi Kohno; Toshiaki Tanaka; Minoru Irie
Effect of growth hormone treatment on trunk fat accumulation in adult GH-deficient Japanese patients: a randomised, placebo-controlled trial.
Current medical research and opinion 2006;22(10):1973-9.
2006: Kentaro Takahashi; Keiji Iida; Kazuo Chihara
[Von Hippel-Lindau disease].
Nihon rinsho. Japanese journal of clinical medicine 2006;Suppl 3():351-4.
2006: Junko Naito; Hiroshi Kaji; Hideaki Sowa; Riko Kitazawa; Sohei Kitazawa; Toshihiko Tsukada; Geoffrey N Hendy; Toshitsugu Sugimoto; Kazuo Chihara
Expression and functional analysis of menin in a multiple endocrine neoplasia type 1 (MEN1) patient with somatic loss of heterozygosity in chromosome 11q13 and unidentified germline mutation of the MEN1 gene.
Endocrine 2006;29(3):485-90.
2006: Hiroshi Kaji; Rikako Nomura; Mika Yamauchi; Kazuo Chihara; Toshitsugu Sugimoto
The usefulness of bone metabolic indices for the prediction of changes in bone mineral density after parathyroidectomy in patients with primary hyperparathyroidism.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2006;38(6):411-6.
2006: Takako Tobimatsu; Hiroshi Kaji; Hideaki Sowa; Junko Naito; Lucie Canaff; Geoffrey N Hendy; Toshitsugu Sugimoto; Kazuo Chihara
Parathyroid hormone increases beta-catenin levels through Smad3 in mouse osteoblastic cells.
Endocrinology 2006;147(5):2583-90.
2006: Kazuo Chihara; Yuzuru Kato; Hitoshi Kohno; Kazue Takano; Toshiaki Tanaka; Akira Teramoto; Akira Shimatsu
Efficacy and safety of growth hormone (GH) in the treatment of adult Japanese patients with GH deficiency: a randomised, placebo-controlled study.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2006;16(2):132-42.
2006: Toshiko Sakuma; Yoshitake Hayashi; Naoki Kanomata; Tohru Murayama; Toshimitsu Matsui; Kazuyoshi Kajimoto; Keisuke Hanioka; Kazuo Chihara; Sakan Maeda
Histological and cytogenetic characterization of bone marrow in relation to prognosis and diagnosis of myelodysplastic syndromes.
Pathology international 2006;56(4):191-9.
2006: Shiro Yoshioka; Yutaka Takahashi; Yasuhiko Okimura; Kentaro Takahashi; Genzo Iguchi; Keiji Iida; Hiroshi Kaji; Kazuo Chihara
Gene expression profile in the heart of spontaneous dwarf rat: in vivo effects of growth hormone.
Biochemical and biophysical research communications 2006;341(1):88-93.
2006: Hiroshi Kaji; Mika Yamauchi; Kazuo Chihara; Toshitsugu Sugimoto
The threshold of bone mineral density for vertebral fracture in female patients with glucocorticoid-induced osteoporosis.
Endocrine journal 2006;53(1):27-34.
2006: Hiroshi Kaji; Mei-Fway Iu; Junko Naito; Toshitsugu Sugimoto; Kazuo Chihara
A case of primary hyperparathyroidism with marked changes in bone mineral density and geometry after parathyroidectomy.
Journal of bone and mineral metabolism 2006;24(4):349-52.
2006: Kentaro Takahashi; Keiji Iida; Yasuhiko Okimura; Yutaka Takahashi; Junko Naito; Shinichiro Nishikawa; Seizo Kadowaki; Genzo Iguchi; Hiroshi Kaji; Kazuo Chihara
A novel mutation in the von Hippel-Lindau tumor suppressor gene identified in a Japanese family with pheochromocytoma and hepatic hemangioma.
Internal medicine (Tokyo, Japan) 2006;45(5):265-9.
2006: Hiroshi Kaji; Takako Tobimatsu; Junko Naito; Mei-Fway Iu; Mika Yamauchi; Toshitsugu Sugimoto; Kazuo Chihara
Body composition and vertebral fracture risk in female patients treated with glucocorticoid.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2006;17(4):627-33.
2005: Hiroshi Kaji; Rieko Kosaka; Mika Yamauchi; Kaoru Kuno; Kazuo Chihara; Toshitsugu Sugimoto
Effects of age, grip strength and smoking on forearm volumetric bone mineral density and bone geometry by peripheral quantitative computed tomography: comparisons between female and male.
Endocrine journal 2005;52(6):659-66.
2005: Norinaga Urahama; Mitsuhiro Ito; Akiko Sada; Kimikazu Yakushijin; Katsuya Yamamoto; Atsuo Okamura; Kentaro Minagawa; Akio Hato; Kazuo Chihara; Robert G Roeder; Toshimitsu Matsui
The role of transcriptional coactivator TRAP220 in myelomonocytic differentiation.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(12):1127-37.
2005: Nobuya Maeda; Fumio Kanda; Shiho Okuda; Hiroyuki Ishihara; Kazuo Chihara
Transforming growth factor-beta enhances connective tissue growth factor expression in L6 rat skeletal myotubes.
Neuromuscular disorders : NMD 2005;15(11):790-3.
2005: Keiji Iida; Yutaka Takahashi; Kazuo Chihara
[Growth disorders caused by mutations of GH-1 or GH receptor gene].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 10():594-601.
2005: Hiroshi Kaji; Kazuo Chihara
[Significance of GH as a regulator of bone metabolism].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 10():551-4.
2005: Hiroshi Kaji; Masanori Kanatani; Toshitsugu Sugimoto; Kazuo Chihara
Statins modulate the levels of osteoprotegerin/receptor activator of NFkappaB ligand mRNA in mouse bone-cell cultures.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2005;37(10):589-92.
2005: Hiroshi Kaji; Mika Yamauchi; Kazuo Chihara; Toshitsugu Sugimoto
The threshold of bone mineral density for vertebral fractures in female patients with primary hyperparathyroidism.
European journal of endocrinology / European Federation of Endocrine Societies 2005;153(3):373-8.
2005: Kazuo Chihara; Ekaterina Koledova; Akira Shimatsu; Yuzuru Kato; Hitoshi Kohno; Toshiaki Tanaka; Akira Teramoto; Peter C Bates; Andrea F Attanasio
An individualized GH dose regimen for long-term GH treatment in Japanese patients with adult GH deficiency.
European journal of endocrinology / European Federation of Endocrine Societies 2005;153(1):57-65.
2005: Mei-Fway Iu; Hiroshi Kaji; Hideaki Sowa; Junko Naito; Toshitsugu Sugimoto; Kazuo Chihara
Dexamethasone suppresses Smad3 pathway in osteoblastic cells.
The Journal of endocrinology 2005;185(1):131-8.
2005: Miki Murata; Yasushi Miura; Akira Hashiramoto; Hitomi Kitamura; Hiroki Kawasaki; Kazuko Shiozawa; Shinichi Yoshiya; Hisamitsu Baba; Kazuo Chihara; Shunichi Shiozawa
Heat shock protein 90 is required for increased DNA binding activity of activator protein-1, a heterodimer of Fos/JunD, in rheumatoid synovial cells under inflammatory stimuli.
International journal of molecular medicine 2005;15(4):649-53.
2005: Junko Naito; Hiroshi Kaji; Hideaki Sowa; Geoffrey N Hendy; Toshitsugu Sugimoto; Kazuo Chihara
Menin suppresses osteoblast differentiation by antagonizing the AP-1 factor, JunD.
The Journal of biological chemistry 2005;280(6):4785-91.
2005: Kimikazu Yakushijin; Toshimitsu Matsui; Atsuo Okamura; Katsuya Yamamoto; Mitsuhiro Ito; Kazuo Chihara
Successful treatment with defibrotide for sinusoidal obstruction syndrome after hematopoietic stem cell transplantation.
The Kobe journal of medical sciences 2005;51(3-4):55-65.
2005: Mei-Fway Iu; Hiroshi Kaji; Junko Naito; Hideaki Sowa; Toshitsugu Sugimoto; Kazuo Chihara
Low-dose parathyroid hormone and estrogen reverse alkaline phosphatase activity suppressed by dexamethasone in mouse osteoblastic cells.
Journal of bone and mineral metabolism 2005;23(6):450-5.
2004: Kenji Sekiguchi; Fumio Kanda; KENICHI OISHI; Hirotoshi Hamaguchi; Kenichiro Nakazawa; Nobuya Maeda; Hiroyuki Ishihara; Kazuo Chihara
HLA typing in focal myositis.
Journal of the neurological sciences 2004;227(1):21-5.
2004: Hirotoshi Hamaguchi; Fumio Kanda; Ichiro Imafuku; Masanari Kunimoto; Kazuo Chihara
Effect of contrast material (Levovist) infusion on peak systolic velocity in middle cerebral artery using transcranial color-coded duplex sonography.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2004;13(6):267-70.
2004: Takako Tobimatsu; Hiroshi Kaji; Junko Naito; Mei-Fway Iu; Rikako Nomura; Hideaki Sowa; Mika Yamauchi; Toshitsugu Sugimoto; Kazuo Chihara; Toshihiko Tsukada
[Case Report No.143: one case of multiple endosecretory-adenomatosis accompanied with ventricula ependymoma].
Clinical calcium 2004;14(10):150-3.
2004: Shiho Okuda; Fumio Kanda; Kunihiko Kawamoto; Kazuo Chihara
Subacute bulbar palsy as the initial sign of follicular thyroid cancer.
Internal medicine (Tokyo, Japan) 2004;43(10):997-9.
2004: Q Chen; Hiroshi Kaji; Masanori Kanatani; Toshitsugu Sugimoto; Kazuo Chihara
Testosterone increases osteoprotegerin mRNA expression in mouse osteoblast cells.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2004;36(10):674-8.
2004: Ryoko Takeno; Yasuhiko Okimura; Genzo Iguchi; Masahiko Kishimoto; Takumi Kudo; Kentaro Takahashi; Yutaka Takahashi; Hiroshi Kaji; Masakazu Ohno; Hajime Ikuta; Yoshikazu Kuroda; Tetsuji Obara; Hiroshi Hosoda; Kenji Kangawa; Kazuo Chihara
Intravenous administration of ghrelin stimulates growth hormone secretion in vagotomized patients as well as normal subjects.
European journal of endocrinology / European Federation of Endocrine Societies 2004;151(4):447-50.
2004: Masanori Kanatani; Toshitsugu Sugimoto; Hideaki Sowa; Tatsuya Kobayashi; Michiko Kanzawa; Kazuo Chihara
Thyroid hormone stimulates osteoclast differentiation by a mechanism independent of RANKL-RANK interaction.
Journal of cellular physiology 2004;201(1):17-25.
2004: Hideaki Sowa; Hiroshi Kaji; Geoffrey N Hendy; Lucie Canaff; Toshihisa Komori; Toshitsugu Sugimoto; Kazuo Chihara
Menin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2.
The Journal of biological chemistry 2004;279(39):40267-75.
2004: Yasuhiko Okimura; Kazuo Chihara
[Ghrelin receptor and its signal transduction].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 9():332-5.
2004: K Iida; M Hanafusa; I Maekawa; T Kudo; K Takahashi; Shiro Yoshioka; Masahiko Kishimoto; Genzo Iguchi; T Tsukamoto; Yasuhiko Okimura; Hiroshi Kaji; Kazuo Chihara
A novel splice site mutation of the thiazide-sensitive NaCl cotransporter gene in a Japanese patient with Gitelman syndrome.
Clinical nephrology 2004;62(3):180-4.
2004: Kazuo Chihara; Ekaterina Koledova; Akira Shimatsu; Yuzuru Kato; Hitoshi Kohno; Toshiaki Tanaka; Akira Teramoto; Peter C Bates; Andrea F Attanasio
Adult GH deficiency in Japanese patients: effects of GH treatment in a randomised, placebo-controlled trial.
European journal of endocrinology / European Federation of Endocrine Societies 2004;151(3):343-50.
2004: Enas Atef Al Naggar; Fumio Kanda; Shiho Okuda; Nobuya Maeda; Ken-Ichiro Nakazawa; KENICHI OISHI; Kenji Sekiguchi; Hiroyuki Ishihara; Kazuo Chihara
Focal myositis in monozygotic twins.
Internal medicine (Tokyo, Japan) 2004;43(7):599-601.
2004: Atsuo Okamura; Nobuko Iwata; Aki Nagata; Akira Tamekane; Manabu Shimoyama; Hiroshi Gomyo; Kimikazu Yakushijin; Norinaga Urahama; Miyuki Hamaguchi; Chie Fukui; Kazuo Chihara; Mitsuhiro Ito; Toshimitsu Matsui
Involvement of casein kinase Iepsilon in cytokine-induced granulocytic differentiation.
Blood 2004;103(8):2997-3004.
2004: Hirotoshi Hamaguchi; Fumio Kanda; Kayo Hosaka; Masahiko Fujii; Kazuo Chihara
[Comparison between MRI and 3D-SSP in olivopontocerebellar atrophy and cortical cerebellar atrophy].
Rinshō shinkeigaku = Clinical neurology 2004;44(4-5):263-7.
2004: Myriam Rosilio; Werner F Blum; David J Edwards; Elena P Shavrikova; Domenico Valle; Steven W J Lamberts; Eva Marie Erfurth; Susan M Webb; Richard J Ross; Kazuo Chihara; Gerhard Henrich; Peter Herschbach; Andrea F Attanasio
Long-term improvement of quality of life during growth hormone (GH) replacement therapy in adults with GH deficiency, as measured by questions on life satisfaction-hypopituitarism (QLS-H).
The Journal of clinical endocrinology and metabolism 2004;89(4):1684-93.
2004: Hideaki Sowa; Hiroshi Kaji; Riko Kitazawa; Sohei Kitazawa; Tatsuo Tsukamoto; Shozo Yano; Toshihiko Tsukada; Lucie Canaff; Geoffrey N Hendy; Toshitsugu Sugimoto; Kazuo Chihara
Menin inactivation leads to loss of transforming growth factor beta inhibition of parathyroid cell proliferation and parathyroid hormone secretion.
Cancer research 2004;64(6):2222-8.
2004: Shiro Yoshioka; Yasuhiko Okimura; Yutaka Takahashi; Keiji Iida; Hiroshi Kaji; Masafumi Matsuo; Kazuo Chihara
Up-regulation of mitochondrial transcription factor 1 mRNA levels by GH in VSMC.
Life sciences 2004;74(17):2097-109.
2004: Rikako Nomura; Toshitsugu Sugimoto; Tatsuo Tsukamoto; Mika Yamauchi; Hideaki Sowa; Qingxiang Chen; Toru Yamaguchi; Akira Kobayashi; Kazuo Chihara
Marked and sustained increase in bone mineral density after parathyroidectomy in patients with primary hyperparathyroidism; a six-year longitudinal study with or without parathyroidectomy in a Japanese population.
Clinical endocrinology 2004;60(3):335-42.
2004: Keiji Iida; Yasuhiko Okimura; Kentaro Takahashi; Sumie Inomata; Genzo Iguchi; Hiroshi Kaji; Kazuo Chihara
A variety of phenotype with R161Q germline mutation of the von Hippel-Lindau tumor suppressor gene in Japanese kindred.
International journal of molecular medicine 2004;13(3):401-4.
2004: Hiroshi Kaji; Kazuo Chihara
Direct causes of death in Japanese patients with hypopituitarism as analyzed from a nation-wide autopsy database.
European journal of endocrinology / European Federation of Endocrine Societies 2004;150(2):149-52.
2004: Enas Atef el-Naggar; Fumio Kanda; Shiho Okuda; Nobuya Maeda; Keisuke Nishimoto; Hiroyuki Ishihara; Kazuo Chihara
Direct effects of tumor necrosis factor alpha (TNF-alpha) on L6 myotubes.
The Kobe journal of medical sciences 2004;50(1-2):39-46.
2004: Mika Yamauchi; Toshitsugu Sugimoto; Kazuo Chihara
Determinants of vertebral fragility: the participation of cortical bone factors.
Journal of bone and mineral metabolism 2004;22(2):79-85.
2003: Hideaki Sowa; Hiroshi Kaji; Mei-Fway Iu; Tatsuo Tsukamoto; Toshitsugu Sugimoto; Kazuo Chihara
Parathyroid hormone-Smad3 axis exerts anti-apoptotic action and augments anabolic action of transforming growth factor beta in osteoblasts.
The Journal of biological chemistry 2003;278(52):52240-52.
2003: Kunihiko Kawamoto; Mamoru Nagano; Fumio Kanda; Kazuo Chihara; Yasufumi Shigeyoshi; Hitoshi Okamura
Two types of VIP neuronal components in rat suprachiasmatic nucleus.
Journal of neuroscience research 2003;74(6):852-7.
2003: Hiroshi Gomyo; Manabu Shimoyama; Kentaro Minagawa; Kimikazu Yakushijin; Norinaga Urahama; Atsuo Okamura; Katsuya Yamamoto; Mitsuhiro Ito; Kazuo Chihara; Yoshitake Hayashi; Toshimitsu Matsui
Morphologic, flow cytometric and cytogenetic evaluation of bone marrow involvement in B-cell lymphoma.
Haematologica 2003;88(12):1358-65.
2003: Keiji Iida; Yutaka Takahashi; Hiroshi Kaji; Shiro Yoshioka; Masahiro Murata; Genzo Iguchi; Yasuhiko Okimura; Kazuo Chihara
Diverse regulation of full-length and truncated growth hormone receptor expression in 3T3-L1 adipocytes.
Molecular and cellular endocrinology 2003;210(1-2):21-9.
2003: Hiroshi Gomyo; Manabu Shimoyama; Kentaro Minagawa; Kimikazu Yakushijin; Norinaga Urahama; Atsuo Okamura; Katsuya Yamamoto; Mitsuhiro Ito; Kazuo Chihara; Toshimitsu Matsui
Effective anti-viral therapy for hemophagocytic syndrome associated with B-cell lymphoma.
Leukemia & lymphoma 2003;44(10):1807-10.
2003: Qingxiang Chen; Hiroshi Kaji; Rikako Nomura; Hideaki Sowa; Mika Yamauchi; Tatsuo Tsukamoto; Toru Yamaguchi; Akira Kobayashi; Toshitsugu Sugimoto; Kazuo Chihara
Trial to predict malignancy of affected parathyroid glands in primary hyperparathyroidism.
Endocrine journal 2003;50(5):527-34.
2003: Qingxiang Chen; Hiroshi Kaji; Mei-Fway Iu; Rikako Nomura; Hideaki Sowa; Mika Yamauchi; Tatsuo Tsukamoto; Toshitsugu Sugimoto; Kazuo Chihara
Effects of an excess and a deficiency of endogenous parathyroid hormone on volumetric bone mineral density and bone geometry determined by peripheral quantitative computed tomography in female subjects.
The Journal of clinical endocrinology and metabolism 2003;88(10):4655-8.
2003: T Sakatani; Hiroshi Kaji; Yutaka Takahashi; Keiji Iida; Yasuhiko Okimura; Kazuo Chihara
Lactogenic hormone responsive element reporter gene activation assay for human growth hormone.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2003;13(5):275-81.
2003: Mariko Fumoto; Yasuhiko Okimura; Yoshio Sakagami; Genzo Iguchi; Masahiko Kishimoto; Yutaka Takahashi; Hiroshi Kaji; Kazuo Chihara
Cloning of a protein binding to the most proximal Pit-1 binding element of prolactin gene from human pituitary cDNA library.
Molecular and cellular endocrinology 2003;207(1-2):31-8.
2003: Junko Naito; Hiroshi Kaji; Mei-Fway Iu; Rikako Nomura; Hideaki Sowa; Qingxiang Chen; Mika Yamauchi; Tatsuo Tsukamoto; Toshitsugu Sugimoto; Kazuo Chihara
[In Process Citation].
Clinical calcium 2003;13(8):1072-6.
2003: Masanori Kanatani; Toshitsugu Sugimoto; Junichi Kano; Michiko Kanzawa; Kazuo Chihara
Effect of high phosphate concentration on osteoclast differentiation as well as bone-resorbing activity.
Journal of cellular physiology 2003;196(1):180-9.
2003: Hideaki Sowa; Hiroshi Kaji; Lucie Canaff; Geoffrey N Hendy; Tatsuo Tsukamoto; Toru Yamaguchi; Kohei Miyazono; Toshitsugu Sugimoto; Kazuo Chihara
Inactivation of menin, the product of the multiple endocrine neoplasia type 1 gene, inhibits the commitment of multipotential mesenchymal stem cells into the osteoblast lineage.
The Journal of biological chemistry 2003;278(23):21058-69.
2003: Masahiko Kishimoto; Yasuhiko Okimura; Mariko Fumoto; Genzo Iguchi; Keiji Iida; Hiroshi Kaji; Kazuo Chihara
The R271W mutant form of Pit-1 does not act as a dominant inhibitor of Pit-1 action to activate the promoters of GH and prolactin genes.
European journal of endocrinology / European Federation of Endocrine Societies 2003;148(6):619-25.
2003: Masahiko Kishimoto; Yasuhiko Okimura; Hirohisa Nakata; Takumi Kudo; Genzo Iguchi; Yutaka Takahashi; Hiroshi Kaji; Kazuo Chihara
Cloning and characterization of the 5(')-flanking region of the human ghrelin gene.
Biochemical and biophysical research communications 2003;305(1):186-92.
2003: Hiroyuki Hori; Hirohisa Nakata; Genzo Iguchi; Hajime Yamada; Kazuo Chihara; Hisamitsu Baba
Oncogenic ras induces gastrin/CCKB receptor gene expression in human colon cancer cell lines LoVo and Colo320HSR.
The Journal of laboratory and clinical medicine 2003;141(5):335-41.
2003: Yasuhiko Okimura; Kiyoharu Ukai; Hiroshi Hosoda; Masahiro Murata; Genzo Iguchi; Keiji Iida; Hiroshi Kaji; Masayasu Kojima; Kenji Kangawa; Kazuo Chihara
The role of circulating ghrelin in growth hormone (GH) secretion in freely moving male rats.
Life sciences 2003;72(22):2517-24.
2003: Qingxiang Chen; Hiroshi Kaji; Mei-Fway Iu; Rikako Nomura; Hideaki Sawa; Mika Yamauchi; Tatsuo Tsukamoto; Toru Yamaguchi; Toshitsugu Sugimoto; Kazuo Chihara; Riko Kitazawa; Akira Kobayashi
[In Process Citation].
Clinical calcium 2003;13(4):496-9.
2003: Tetsuya Makino; Toshitsugu Sugimoto; Hiroshi Kaji; Toru Yamaguchi; Riko Kitazawa; Mika Yamauchi; Hideaki Sowa; Qingxiang Chen; Rikako Nomura; Tatsuo Tsukamoto; Kazuo Chihara
Functional giant parathyroid cyst with high concentration of CA19-9 in cystic fluid.
Endocrine journal 2003;50(2):215-9.
2003: Hiroshi Kaji; Saburo Hattori; Kenichi Sekita; Toshitsugu Sugimoto; Kazuo Chihara
Factors affecting bone mineral density in hemodialysis patients with diabetic nephropathy.
Endocrine journal 2003;50(2):127-33.
2003: Shozo Yano; Toshitsugu Sugimoto; Tatsuo Tsukamoto; Toru Yamaguchi; T Hattori; KI Sekita; Hiroshi Kaji; S Hattori; Akiko Kobayashi; Kazuo Chihara
Effect of parathyroidectomy on bone mineral density in hemodialysis patients with secondary hyperparathyroidism: possible usefulness of preoperative determination of parathyroid hormone level for prediction of bone regain.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2003;35(4):259-64.
2003: Shiro Yoshioka; Tatsuo Tsukamoto; Kazuo Chihara
[Vascular smooth muscle cells in coronary heart disease].
Nihon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 4():80-5.
2003: Shozo Yano; Toshitsugu Sugimoto; Tatsuo Tsukamoto; Kazuo Chihara; Akira Kobayashi; Sohei Kitazawa; Sakan Maeda; Riko Kitazawa
Decrease in vitamin D receptor and calcium-sensing receptor in highly proliferative parathyroid adenomas.
European journal of endocrinology / European Federation of Endocrine Societies 2003;148(4):403-11.
2003: Masahiro Murata; Hiroshi Kaji; Ishikazu Mizuno; Tatsuya Sakurai; Keiji Iida; Yasuhiko Okimura; Kazuo Chihara
A study of carotid intima-media thickness in GH-deficient Japanese adults during onset among adults and children.
European journal of endocrinology / European Federation of Endocrine Societies 2003;148(3):333-8.
2003: Yoshio Sakagami; Yasuhiko Okimura; Takeshi Kondoh; Genzo Iguchi; Mariko Fumoto; Takayoshi Kuno; Kazuo Chihara; Eiji Kohmura
Expression of mPOU protein in the human pituitary adenomas.
The Kobe journal of medical sciences 2003;49(5-6):117-22.
2002: Koichiro Komai; Rie Okayama; Michinori Kitagawa; Hirofumi Yagi; Kazuo Chihara; Shunichi Shiozawa
Alternative splicing variants of the human DBL (MCF-2) proto-oncogene.
Biochemical and biophysical research communications 2002;299(3):455-8.
2002: Hiroshi Kaji; Tatsuya Sakurai; Genzo Iguchi; Masahiro Murata; Masahiko Kishimoto; Shimou Yoshioka; Keiji Iida; Yasuhiko Okimura; Kazuo Chihara
Adult growth hormone deficiency in Japan: results of investigation by questionnaire.
Endocrine journal 2002;49(6):597-604.
2002: Kazuo Chihara
Syndromes of growth hormone bioinactivity.
Journal of pediatric endocrinology & metabolism : JPEM 2002;15 Suppl 5():1437-8.
2002: Mika Yamauchi; Toshitsugu Sugimoto; Toru Yamaguchi; Shozo Yano; Junning Wang; Mei Bai; Edward M Brown; Kazuo Chihara
Familial hypocalciuric hypercalcemia caused by an R648stop mutation in the calcium-sensing receptor gene.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(12):2174-82.
2002: Tatsuya Sakurai; Keiji Iida; Yutaka Takahashi; Hiroshi Kaji; Satoshi Takakuwa; Ryou Sumita; Yasuhiko Okimura; Kazuo Chihara
A novel heterozygous T51I mutation of growth hormone receptor is not associated with short stature.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 2002;12(6):411-7.
2002: Masahiko Kishimoto; Yasuhiko Okimura; Kazuhiro Yagita; Genzo Iguchi; Mariko Fumoto; Keiji Iida; Hiroshi Kaji; Hitoshi Okamura; Kazuo Chihara
Novel function of the transactivation domain of a pituitary-specific transcription factor, Pit-1.
The Journal of biological chemistry 2002;277(47):45141-8.
2002: Hideaki Sowa; Hiroshi Kaji; Toru Yamaguchi; Toshitsugu Sugimoto; Kazuo Chihara
Activations of ERK1/2 and JNK by transforming growth factor beta negatively regulate Smad3-induced alkaline phosphatase activity and mineralization in mouse osteoblastic cells.
The Journal of biological chemistry 2002;277(39):36024-31.
2002: Toshitsugu Sugimoto; Hiroshi Kaji; Daiki Nakaoka; Mika Yamauchi; Shozo Yano; Takeshi Sugishita; David J Baylink; Subburaman Mohan; Kazuo Chihara
Effect of low-dose of recombinant human growth hormone on bone metabolism in elderly women with osteoporosis.
European journal of endocrinology / European Federation of Endocrine Societies 2002;147(3):339-48.
2002: Nobuya Maeda; Fumio Kanda; Kenichiro Nakazawa; Kazuo Chihara
[McArdle's disease with insulin resistance caused by obesity].
Rinshō shinkeigaku = Clinical neurology 2002;42(7):632-4.
2002: Hideaki Sowa; Hiroshi Kaji; Toru Yamaguchi; Toshitsugu Sugimoto; Kazuo Chihara
Smad3 promotes alkaline phosphatase activity and mineralization of osteoblastic MC3T3-E1 cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2002;17(7):1190-9.
2002: Rieko Ozuru; Toshitsugu Sugimoto; Tohru Yamaguchi; Kazuo Chihara
Time-dependent effects of vitamin K2 (menatetrenone) on bone metabolism in postmenopausal women.
Endocrine journal 2002;49(3):363-70.
2002: Toru Yamaguchi; Toshitsugu Sugimoto; Shozo Yano; Mika Yamauchi; Hideaki Sowa; Qingxiang Chen; Kazuo Chihara
Plasma lipids and osteoporosis in postmenopausal women.
Endocrine journal 2002;49(2):211-7.
2002: Masanori Kanatani; Toshitsugu Sugimoto; Junichi Kano; Kazuo Chihara
IGF-I mediates the stimulatory effect of high phosphate concentration on osteoblastic cell proliferation.
Journal of cellular physiology 2002;190(3):306-12.
2002: Masahiro Murata; Yasuhiko Okimura; Keiji Iida; Michihiro Matsumoto; Hideaki Sowa; Hiroshi Kaji; Masayasu Kojima; Kenji Kangawa; Kazuo Chihara
Ghrelin modulates the downstream molecules of insulin signaling in hepatoma cells.
The Journal of biological chemistry 2002;277(7):5667-74.
2002: Toru Yamaguchi; Toshitsugu Sugimoto; H Yamada; Michiko Kanzawa; Shozo Yano; Mika Yamauchi; Kazuo Chihara
The presence and severity of vertebral fractures is associated with the presence of esophageal hiatal hernia in postmenopausal women.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2002;13(4):331-6.
2002: Riko Kitazawa; Sohei Kitazawa; Kazuyoshi Kajimoto; Hideaki Sowa; Toshitsugu Sugimoto; Tosimitsu Matsui; Kazuo Chihara; Sakan Maeda
Expression of parathyroid hormone-related protein (PTHrP) in multiple myeloma.
Pathology international 2002;52(1):63-8.
2001: Hiroshi Kaji; Kazuo Chihara
[Short stature by growth hormone deficiency].
Nihon rinsho. Japanese journal of clinical medicine 2001;59 Suppl 8():30-7.
2001: Mika Yamauchi; Toshitsugu Sugimoto; Toru Yamaguchi; Shozo Yano; Michiko Kanzawa; Akiko Kobayashi; Kazuo Chihara
Association of polymorphic alleles of the calcium-sensing receptor gene with the clinical severity of primary hyperparathyroidism.
Clinical endocrinology 2001;55(3):373-9.
2001: Mika Yamauchi; Toshitsugu Sugimoto; Toru Yamaguchi; Daiki Nakaoka; Michiko Kanzawa; Shozo Yano; R Ozuru; Takeshi Sugishita; Kazuo Chihara
Plasma leptin concentrations are associated with bone mineral density and the presence of vertebral fractures in postmenopausal women.
Clinical endocrinology 2001;55(3):341-7.
2001: Masahiro Murata; Hiroshi Kaji; Keiji Iida; Yasuhiko Okimura; Kazuo Chihara
Dual action of eicosapentaenoic acid in hepatoma cells: up-regulation of metabolic action of insulin and inhibition of cell proliferation.
The Journal of biological chemistry 2001;276(33):31422-8.
2001: Y Tokukoda; S Takata; Hiroshi Kaji; Riko Kitazawa; Toshitsugu Sugimoto; Kazuo Chihara
Interleukin-1beta stimulates transendothelial mobilization of human peripheral blood mononuclear cells with a potential to differentiate into osteoclasts in the presence of osteoblasts.
Endocrine journal 2001;48(4):443-52.
2001: Hiroshi Kaji; Toshitsugu Sugimoto; Daiki Nakaoka; Yasuhiko Okimura; H Kaji; H Abe; Kazuo Chihara
Bone metabolism and body composition in Japanese patients with active acromegaly.
Clinical endocrinology 2001;55(2):175-81.
2001: Hiroshi Kaji; Masahiko Kishimoto; T Kirimura; Genzo Iguchi; M Murata; S Yoshioka; K Iida; Yasuhiko Okimura; Y Yoshimoto; Kazuo Chihara
Hormonal regulation of the human ghrelin receptor gene transcription.
Biochemical and biophysical research communications 2001;284(3):660-6.
2001: I Mizuno; Yutaka Takahashi; Yasuhiko Okimura; Hiroshi Kaji; Kazuo Chihara
Upregulation of the klotho gene expression by thyroid hormone and during adipose differentiation in 3T3-L1 adipocytes.
Life sciences 2001;68(26):2917-23.
2001: Kenichiro Nakazawa; Fumio Kanda; H Ishihara; T Matsushita; Kazuo Chihara
[A case of cephalic tetanus presenting with opisthotonus].
Rinshō shinkeigaku = Clinical neurology 2001;41(4-5):187-90.
2001: Masanori Kanatani; Toshitsugu Sugimoto; Hiroshi Kaji; K Ikeda; Kazuo Chihara
Skeletal responsiveness to parathyroid hormone in pseudohypoparathyroidism.
European journal of endocrinology / European Federation of Endocrine Societies 2001;144(3):263-9.
2001: Q Chen; Hiroshi Kaji; Toshitsugu Sugimoto; Kazuo Chihara
Testosterone inhibits osteoclast formation stimulated by parathyroid hormone through androgen receptor.
FEBS letters 2001;491(1-2):91-3.
2001: Fumio Kanda; S Okuda; T Matsushita; K Takatani; K I Kimura; Kazuo Chihara
Steroid myopathy: pathogenesis and effects of growth hormone and insulin-like growth factor-I administration.
Hormone research 2001;56 Suppl 1():24-8.
2001: Daiki Nakaoka; Toshitsugu Sugimoto; Hiroshi Kaji; Michiko Kanzawa; Shozo Yano; Mika Yamauchi; Takeshi Sugishita; Kazuo Chihara
Determinants of bone mineral density and spinal fracture risk in postmenopausal Japanese women.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2001;12(7):548-54.
2000: M Nasu; Toshitsugu Sugimoto; Hiroshi Kaji; Kazuo Chihara
Estrogen modulates osteoblast proliferation and function regulated by parathyroid hormone in osteoblastic SaOS-2 cells: role of insulin-like growth factor (IGF)-I and IGF-binding protein-5.
The Journal of endocrinology 2000;167(2):305-13.
2000: Shozo Yano; Toshitsugu Sugimoto; Tatsuo Tsukamoto; Kazuo Chihara; Akiko Kobayashi; Sohei Kitazawa; Sakan Maeda; Riko Kitazawa
Association of decreased calcium-sensing receptor expression with proliferation of parathyroid cells in secondary hyperparathyroidism.
Kidney international 2000;58(5):1980-6.
2000: Masahiko Kishimoto; Yasuhiko Okimura; Shuji Hinuma; Shoji Fukusumi; Genzo Iguchi; Mariko Fumoto; Keiji Iida; Hiroshi Kaji; Kazuo Chihara
Cloning and characterization of the 5'-flanking region of the human prolactin-releasing peptide receptor gene.
Biochemical and biophysical research communications 2000;276(2):411-6.
2000: Michiko Kanzawa; Toshitsugu Sugimoto; Tatsuya Kobayashi; Akiko Kobayashi; Kazuo Chihara
Association between parathyroid hormone (PTH)/PTH-related peptide receptor gene polymorphism and the extent of bone mass reduction in primary hyperparathyroidism.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2000;32(9):355-8.
2000: Toshimitsu Matsui; R Inoue; K Kajimoto; Akira Tamekane; Atsuo Okamura; Yoshio Katayama; Manabu Shimoyama; Kazuo Chihara; Atsuko Saito-Ito; Masayoshi Tsuji
[First documentation of transfusion-associated babesiosis in Japan].
[Rinshō ketsueki] The Japanese journal of clinical hematology 2000;41(8):628-34.
2000: Shozo Yano; Toshitsugu Sugimoto; Michiko Kanzawa; Tatsuo Tsukamoto; T Hattori; S Hattori; Kazuo Chihara
Association of polymorphic alleles of the calcium-sensing receptor gene with parathyroid hormone secretion in hemodialysis patients.
Nephron 2000;85(4):317-23.
2000: K Shimizu; H Kawasaki; T Morisawa; M Nakamura; Eri Yamamoto; N Yoshikawa; M Doita; Kazuko Shiozawa; S Yonehara; Kazuo Chihara; Shunichi Shiozawa
Spontaneous and cytokine regulated c-fos gene expression in rheumatoid synovial cells: resistance to cytokine stimulation when the c-fos gene is overexpressed.
Annals of the rheumatic diseases 2000;59(8):636-40.
2000: Masahiko Kishimoto; Yasuhiko Okimura; K Kimura; Ishikazu Mizuno; Genzo Iguchi; Mariko Fumoto; Yutaka Takahashi; Fumio Kanda; Hiroshi Kaji; H Abe; Keisuke Hanioka; Kazuo Chihara
Multifocal fibrosclerosis as a possible cause of panhypopituitarism with central diabetes insipidus.
Endocrine journal 2000;47(3):335-42.
2000: Daiki Nakaoka; Toshitsugu Sugimoto; Tatsuya Kobayashi; Toru Yamaguchi; Akiko Kobayashi; Kazuo Chihara
Evaluation of changes in bone density and biochemical parameters after parathyroidectomy in primary hyperparathyroidism.
Endocrine journal 2000;47(3):231-7.
2000: Toru Yamaguchi; Toshitsugu Sugimoto; Kazuo Chihara
Treatment of osteopenia secondary to primary hyperparathyroidism.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2000;54 Suppl 1():104s-107s.
2000: Michiko Kanzawa; Toshitsugu Sugimoto; Masanori Kanatani; Kazuo Chihara
Involvement of osteoprotegerin/osteoclastogenesis inhibitory factor in the stimulation of osteoclast formation by parathyroid hormone in mouse bone cells.
European journal of endocrinology / European Federation of Endocrine Societies 2000;142(6):661-4.
2000: Daiki Nakaoka; Toshitsugu Sugimoto; Tatsuya Kobayashi; Toru Yamaguchi; Akiko Kobayashi; Kazuo Chihara
Prediction of bone mass change after parathyroidectomy in patients with primary hyperparathyroidism.
The Journal of clinical endocrinology and metabolism 2000;85(5):1901-7.
2000: Masanori Kanatani; Toshitsugu Sugimoto; K Nishiyama; Kazuo Chihara
Stimulatory effect of insulin-like growth factor binding protein-5 on mouse osteoclast formation and osteoclastic bone-resorbing activity.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(5):902-10.
2000: M Murata; Hiroshi Kaji; Yutaka Takahashi; Keiji Iida; I Mizuno; Yasuhiko Okimura; H Abe; Kazuo Chihara
Stimulation by eicosapentaenoic acids of leptin mRNA expression and its secretion in mouse 3T3-L1 adipocytes in vitro.
Biochemical and biophysical research communications 2000;270(2):343-8.
2000: Manabu Shimoyama; Hiroshi Matsuoka; Akira Tamekane; Mitsuhiro Ito; Nobuko Iwata; R Inoue; Kazuo Chihara; A Furuya; Nobuo Hanai; Toshimitsu Matsui
T-cell-specific expression of kinase-defective Eph-family receptor protein, EphB6 in normal as well as transformed hematopoietic cells.
Growth factors (Chur, Switzerland) 2000;18(1):63-78.
2000: R Inoue; T Natazuka; Manabu Shimoyama; Akira Tamekane; Y Kajimoto; Nobuko Iwata; Hiroshi Matsuoka; Kazuo Chihara; Toshimitsu Matsui
Feasibility of high-dose chemotherapy without stem cell support as a first-line treatment for non-Hodgkin's aggressive lymphoma: a pilot study.
Leukemia & lymphoma 2000;36(3-4):315-21.
1999: Toshitsugu Sugimoto; Daiki Nakaoka; M Nasu; Michiko Kanzawa; Takeshi Sugishita; Kazuo Chihara
Effect of recombinant human growth hormone in elderly osteoporotic women.
Clinical endocrinology 1999;51(6):715-24.
1999: Keiji Iida; Yutaka Takahashi; Hiroshi Kaji; N Onodera; M O Takahashi; Yasuhiko Okimura; H Abe; Kazuo Chihara
The C422F mutation of the growth hormone receptor gene is not responsible for short stature.
The Journal of clinical endocrinology and metabolism 1999;84(11):4214-9.
1999: I Mizuno; Yasuhiko Okimura; Yutaka Takahashi; Hiroshi Kaji; H Abe; Kazuo Chihara
Leptin stimulates basal and GHRH-induced GH release from cultured rat anterior pituitary cells in vitro.
The Kobe journal of medical sciences 1999;45(5):221-7.
1999: Mikiko Takahashi; Yutaka Takahashi; Keiji Iida; Yasuhiko Okimura; Hiroshi Kaji; H Abe; Kazuo Chihara
Growth hormone stimulates tyrosine phosphorylation of focal adhesion kinase (p125(FAK)) and actin stress fiber formation in human osteoblast-like cells, Saos2.
Biochemical and biophysical research communications 1999;263(1):100-6.
1999: Masanori Kanatani; Toshitsugu Sugimoto; Michiko Kanzawa; Shozo Yano; Kazuo Chihara
High extracellular calcium inhibits osteoclast-like cell formation by directly acting on the calcium-sensing receptor existing in osteoclast precursor cells.
Biochemical and biophysical research communications 1999;261(1):144-8.
1999: Yutaka Takahashi; Kazuo Chihara
Short stature by mutant growth hormones.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 1999;9 Suppl B():37-40; discussion 40-1.
1999: Michiko Kanzawa; Toshitsugu Sugimoto; Tatsuya Kobayashi; Akiko Kobayashi; Kazuo Chihara
Parathyroid hormone gene polymorphisms in primary hyperparathyroidism.
Clinical endocrinology 1999;50(5):583-8.
1999: Genzo Iguchi; Yasuhiko Okimura; Tomosaburo Takahashi; Ishikazu Mizuno; Mariko Fumoto; Yutaka Takahashi; Hiroshi Kaji; H Abe; Kazuo Chihara
Cloning and characterization of the 5'-flanking region of the human growth hormone-releasing hormone receptor gene.
The Journal of biological chemistry 1999;274(17):12108-14.
1999: Keiji Iida; Yutaka Takahashi; Hiroshi Kaji; M O Takahashi; Yasuhiko Okimura; O Nose; H Abe; Kazuo Chihara
Functional characterization of truncated growth hormone (GH) receptor-(1-277) causing partial GH insensitivity syndrome with high GH-binding protein.
The Journal of clinical endocrinology and metabolism 1999;84(3):1011-6.
1998: Hiroshi Kaji; S Tai; Yasuhiko Okimura; Genzo Iguchi; Yutaka Takahashi; H Abe; Kazuo Chihara
Cloning and characterization of the 5'-flanking region of the human growth hormone secretagogue receptor gene.
The Journal of biological chemistry 1998;273(51):33885-8.
1998: Shiho Okuda; Fumio Kanda; Kentaro Takahashi; Chiharu Kawanami; Yoshikazu Kinoshita; M Fujita; Sakan Maeda; Kenji Jinnai; T Matsushita; T Sugio; T Sugimoto; Kazuo Chihara
Fatal liver cirrhosis and esophageal variceal hemorrhage in a patient with type IIIa glycogen storage disease.
Internal medicine (Tokyo, Japan) 1998;37(12):1055-7.
1998: Y Takahashi; Kazuo Chihara
Clinical significance and molecular mechanisms of bioinactive growth hormone (review).
International journal of molecular medicine 1998;2(3):287-91.
1998: Ishikazu Mizuno; O Izeki; S Nakahara; K Kawamoto; Takafumi Onga; H Matsuoka; T Sugimoto; Toshimitsu Matsui; H Itoh; Kazuo Chihara
[Disseminated carcinomatosis of the bone marrow occurring 11 years after subtotal gastrectomy for gastric cancer].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1998;39(9):670-5.
1998: Ishikazu Mizuno; Tohru Murayama; Chiho Obayashi; K Takahashi; Y Miyata; M Ando; M Sato; Shion Imoto; Toshimitsu Matsui; H Itoh; Kazuo Chihara
[Multicentric Castleman's disease with lymphoid interstitial pneumonia and polyneuropathy].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1998;39(8):593-9.
1998: Toshitsugu Sugimoto; Daiki Nakaoka; M Nasu; Michiko Kanzawa; Takeshi Sugishita; Kazuo Chihara
Age-dependent changes in body composition in postmenopausal Japanese women: relationship to growth hormone secretion as well as serum levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.
European journal of endocrinology / European Federation of Endocrine Societies 1998;138(6):633-9.
1998: Masanori Kanatani; Toshitsugu Sugimoto; Y Takahashi; Hiroshi Kaji; Riko Kitazawa; Kazuo Chihara
Estrogen via the estrogen receptor blocks cAMP-mediated parathyroid hormone (PTH)-stimulated osteoclast formation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998;13(5):854-62.
1998: M Nasu; Toshitsugu Sugimoto; Hiroshi Kaji; Junichi Kano; Kazuo Chihara
Carboxyl-terminal parathyroid hormone fragments stimulate type-1 procollagen and insulin-like growth factor-binding protein-5 mRNA expression in osteoblastic UMR-106 cells.
Endocrine journal 1998;45(2):229-34.
1998: Tatsuya Kobayashi; Toshitsugu Sugimoto; Michiko Kanzawa; Kazuo Chihara
Identification of an enhancer sequence in 5'-flanking region of 1A exon of mouse liver/bone/kidney-type alkaline phosphatase gene.
Biochemistry and molecular biology international 1998;44(4):683-91.
1998: Tatsuya Kobayashi; Toshitsugu Sugimoto; Akiko Kobayashi; Kazuo Chihara
Vitamin D receptor genotype is associated with cortical bone loss in Japanese patients with primary hyperparathyroidism.
Endocrine journal 1998;45(1):123-5.
1998: Keiji Iida; Yutaka Takahashi; Hiroshi Kaji; O Nose; Yasuhiko Okimura; H Abe; Kazuo Chihara
Growth hormone (GH) insensitivity syndrome with high serum GH-binding protein levels caused by a heterozygous splice site mutation of the GH receptor gene producing a lack of intracellular domain.
The Journal of clinical endocrinology and metabolism 1998;83(2):531-7.
1998: Kazuo Chihara; Yutaka Takahashi; Hiroshi Kaji; Katsumi Goji; Yasuhiko Okimura; H Abe
Short stature caused by a natural growth hormone antagonist.
Hormone research 1998;49 Suppl 1():41-5.
1997: K Iida; Hiroshi Kaji; H Matsumoto; Yasuhiko Okimura; H Abe; Masato Fujisawa; Sadao Kamidono; Kazuo Chihara
Adrenocorticotrophin-independent macronodular adrenal hyperplasia in a patient with lysine vasopressin responsiveness but insensitivity to gastric inhibitory polypeptide.
Clinical endocrinology 1997;47(6):739-45.
1997: T Matsushita; Fumio Kanda; H Yamada; Kazuo Chihara
[Recurrent acute transverse myelopathy: an 83-year-old man with antiphospholipid syndrome].
Rinshō shinkeigaku = Clinical neurology 1997;37(11):987-91.
1997: Hiroshi Kaji; O Nose; H Tajiri; Yutaka Takahashi; Keiji Iida; T Takahashi; Yasuhiko Okimura; H Abe; Kazuo Chihara
Novel compound heterozygous mutations of growth hormone (GH) receptor gene in a patient with GH insensitivity syndrome.
The Journal of clinical endocrinology and metabolism 1997;82(11):3705-9.
1997: T Kobayashi; Toshitsugu Sugimoto; K Saijoh; M Fukase; Kazuo Chihara
Cloning of mouse diastrophic dysplasia sulfate transporter gene induced during osteoblast differentiation by bone morphogenetic protein-2.
Gene 1997;198(1-2):341-9.
1997: T Kobayashi; Toshitsugu Sugimoto; K Saijoh; Makiko Fujii; Kazuo Chihara
Cloning and characterization of the 5'-flanking region of the mouse diastrophic dysplasia sulfate transporter gene.
Biochemical and biophysical research communications 1997;238(3):738-43.
1997: Yutaka Takahashi; Hiroyuki Shirono; O Arisaka; Kenichi Takahashi; T Yagi; Junichi Koga; Hiroshi Kaji; Yasuhiko Okimura; H Abe; Toshiaki Tanaka; Kazuo Chihara
Biologically inactive growth hormone caused by an amino acid substitution.
The Journal of clinical investigation 1997;100(5):1159-65.
1997: Tatsuya Kobayashi; Toshitsugu Sugimoto; Kazuo Chihara
Clinical and biochemical presentation of primary hyperparathyroidism in Kansai district of Japan.
Endocrine journal 1997;44(4):595-601.
1997: Toshitsugu Sugimoto; K Nishiyama; F Kuribayashi; Kazuo Chihara
Serum levels of insulin-like growth factor (IGF) I, IGF-binding protein (IGFBP)-2, and IGFBP-3 in osteoporotic patients with and without spinal fractures.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(8):1272-9.
1997: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; K Nishiyama; M Nasu; Kazuo Chihara
Insulin-like growth factor-I mediates osteoclast-like cell formation stimulated by parathyroid hormone.
Journal of cellular physiology 1997;172(1):55-62.
1997: Hiroshi Matsuoka; Nobuko Iwata; Mitsuhiro Ito; Manabu Shimoyama; Aki Nagata; Kazuo Chihara; S Takai; Toshimitsu Matsui
Expression of a kinase-defective Eph-like receptor in the normal human brain.
Biochemical and biophysical research communications 1997;235(3):487-92.
1997: M Nasu; Toshitsugu Sugimoto; Kazuo Chihara
Stimulatory effects of parathyroid hormone and 1,25-dihydroxyvitamin D3 on insulin-like growth factor-binding protein-5 mRNA expression in osteoblastic UMR-106 cells: the difference between transient and continuous treatments.
FEBS letters 1997;409(1):63-6.
1997: S Wada; Hiroshi Kaji; K Yoshimura; Kazuo Chihara
Characterization of GH3 cells overexpressing basic fibroblast growth factor (FGF-2).
Journal of neuroendocrinology 1997;9(6):423-30.
1997: M Nasu; Toshitsugu Sugimoto; M Chihara; M Hiraumi; F Kurimoto; Kazuo Chihara
Effect of natural menopause on serum levels of IGF-I and IGF-binding proteins: relationship with bone mineral density and lipid metabolism in perimenopausal women.
European journal of endocrinology / European Federation of Endocrine Societies 1997;136(6):608-16.
1997: Yutaka Takahashi; Yasuhiko Okimura; Ishikazu Mizuno; Keiji Iida; Tomosaburo Takahashi; Hiroshi Kaji; H Abe; Kazuo Chihara
Leptin induces mitogen-activated protein kinase-dependent proliferation of C3H10T1/2 cells.
The Journal of biological chemistry 1997;272(20):12897-900.
1997: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; K Nishiyama; Kazuo Chihara
Dexamethasone stimulates osteoclast-like cell formation by directly acting on hemopoietic blast cells and enhances osteoclast-like cell formation stimulated by parathyroid hormone and prostaglandin E2.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(5):734-41.
1997: Yasufumi Shigeyoshi; T Ogura; H Esumi; Kazuo Chihara; Yasuhiko Ibata; Hitoshi Okamura
Lesion-induced neuronal nitric oxide synthase in Purkinje cells of the rat cerebellar cortex: histochemical and in situ hybridization study.
Brain research. Molecular brain research 1997;44(2):229-37.
1997: Kazuo Chihara; Toshitsugu Sugimoto
The action of GH/IGF-I/IGFBP in osteoblasts and osteoclasts.
Hormone research 1997;48 Suppl 5():45-9.
1996: Yutaka Takahashi; Yasuhiko Okimura; Ishikazu Mizuno; Tomosaburo Takahashi; Hiroshi Kaji; T Uchiyama; H Abe; Kazuo Chihara
Leptin induces tyrosine phosphorylation of cellular proteins including STAT-1 in human renal adenocarcinoma cells, ACHN.
Biochemical and biophysical research communications 1996;228(3):859-64.
1996: M Mitani; Hiroshi Kaji; H Abe; Kazuo Chihara
Growth hormone (GH)-releasing peptide and GH releasing hormone stimulate GH release from subpopulations of somatotrophs in rats.
Journal of neuroendocrinology 1996;8(11):825-30.
1996: A Nagata; M Ito; N Iwata; Junko Kuno; H Takano; Osamu Minowa; Kazuo Chihara; Toshimitsu Matsui; T Noda
G protein-coupled cholecystokinin-B/gastrin receptors are responsible for physiological cell growth of the stomach mucosa in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11825-30.
1996: Yutaka Takahashi; Hiroshi Kaji; Yasuhiko Okimura; K Goji; H Abe; Kazuo Chihara
Short stature caused by a mutant growth hormone with an antagonistic effect.
Endocrine journal 1996;43 Suppl():S27-32.
1996: Y Xu; Hiroshi Kaji; Yasuhiko Okimura; Toshimitsu Matsui; H Abe; Kazuo Chihara
Paracrine stimulation of cell growth by cholecystokinin/gastrin through cholecystokinin-B receptor on GH3 cells in vitro.
Neuroendocrinology 1996;64(4):280-5.
1996: N Iwata; T Murayama; Y Matsumori; M Ito; A Nagata; Tadatsugu Taniguchi; Kazuo Chihara; Y Matsuo; J Minowada; Toshimitsu Matsui
Autocrine loop through cholecystokinin-B/gastrin receptors involved in growth of human leukemia cells.
Blood 1996;88(7):2683-9.
1996: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; Kazuo Chihara
High extracellular calcium stimulates osteoclast-like cell formation and bone-resorbing activity in the presence of osteoblastic cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(7):912-20.
1996: T Murayama; Y Matsumori; N Iwata; M Ito; Tadatsugu Taniguchi; Kazuo Chihara; Toshimitsu Matsui
Antiproliferative effect of a novel cholecystokinin-B/gastrin receptor antagonist, YM022.
Japanese journal of cancer research : Gann 1996;87(7):743-50.
1996: T Matsushita; Fumio Kanda; T Sugio; S Okuda; Kazuo Chihara
[Growth hormone prevents the steroid myopathy in rats].
Rinshō shinkeigaku = Clinical neurology 1996;36(6):752-6.
1996: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; M Nasu; Kazuo Chihara
Estrogen blocks parathyroid hormone (PTH)-stimulated osteoclast-like cell formation by selectively affecting PTH-responsive cyclic adenosine monophosphate pathway.
Endocrinology 1996;137(6):2217-24.
1996: H Miyake; Isao Hara; K Yoshimura; H Eto; Soichi Arakawa; S Wada; Kazuo Chihara; Sadao Kamidono
Introduction of basic fibroblast growth factor gene into mouse renal cell carcinoma cell line enhances its metastatic potential.
Cancer research 1996;56(10):2440-5.
1996: S Chujo; Hiroshi Kaji; Yutaka Takahashi; Yasuhiko Okimura; H Abe; Kazuo Chihara
No correlation of growth hormone receptor gene mutation P561T with body height.
European journal of endocrinology / European Federation of Endocrine Societies 1996;134(5):560-2.
1996: Tadatsugu Taniguchi; K Takaishi; T Murayama; M Ito; N Iwata; Kazuo Chihara; Takuya Sasaki; Yoshimi Takai; Toshimitsu Matsui
Cholecystokinin-B/gastrin receptors mediate rapid formation of actin stress fibers.
Oncogene 1996;12(6):1357-60.
1996: Yutaka Takahashi; Hiroshi Kaji; Yasuhiko Okimura; K Goji; H Abe; Kazuo Chihara
Brief report: short stature caused by a mutant growth hormone.
The New England journal of medicine 1996;334(7):432-6.
1996: H Yagi; Hiroshi Kaji; M Sato; Yasuhiko Okimura; Kazuo Chihara
Effect of intravenous or intracerebroventricular injections of His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 on GH release in conscious, freely moving male rats.
Neuroendocrinology 1996;63(2):198-206.
1996: T Yamaguchi; M Fukase; Kazuo Chihara
The hydrolysis of parathyroid hormone by papain-solubilized rat meprin differs from that of detergent-solubilized meprin.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1996;28(2):111-3.
1996: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; M Fukase; Masayoshi Kumegawa; Kazuo Chihara
Prostaglandin E2 stimulates osteoclast-like cell formation and bone-resorbing activity via osteoblasts: role of cAMP-dependent protein kinase.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(1):62-71.
1996: K Nishiyama; Toshitsugu Sugimoto; Hiroshi Kaji; Masanori Kanatani; T Kobayashi; Kazuo Chihara
Stimulatory effect of growth hormone on bone resorption and osteoclast differentiation.
Endocrinology 1996;137(1):35-41.
1995: Masanori Kanatani; Toshitsugu Sugimoto; Hiroshi Kaji; T Kobayashi; K Nishiyama; M Fukase; Masayoshi Kumegawa; Kazuo Chihara
Stimulatory effect of bone morphogenetic protein-2 on osteoclast-like cell formation and bone-resorbing activity.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(11):1681-90.
1995: Masanori Kanatani; Toshitsugu Sugimoto; Hiroshi Kaji; J Kano; Kazuo Chihara
Effects of 22-oxacalcitriol on bone metabolism in vitro: comparison with calcitriol--effects of 22-oxacalcitriol on osteoclast-like cell formation and bone-resorbing activity.
European journal of endocrinology / European Federation of Endocrine Societies 1995;133(5):618-25.
1995: Tomosaburo Takahashi; Yasuhiko Okimura; K Yoshimura; Yasufumi Shigeyoshi; Hiroshi Kaji; H Abe; Kazuo Chihara
Regional distribution of growth hormone-releasing hormone (GHRH) receptor mRNA in the rat brain.
Endocrinology 1995;136(10):4721-4.
1995: S Tai; Hiroshi Kaji; Yasuhiko Okimura; H Abe; Kazuo Chihara
Neurokinin receptor antagonists inhibit the binding of growth hormone-releasing peptide to EP-1 human neuroblastoma cells.
Biochemical and biophysical research communications 1995;214(2):454-60.
1995: Y Kuroki; S Shiozawa; J Kano; Kazuo Chihara
Competition between c-fos and 1,25(OH)2 vitamin D3 in the transcriptional control of type I collagen synthesis in MC3T3-E1 osteoblastic cells.
Journal of cellular physiology 1995;164(3):459-64.
1995: K Yoshimura; Hiroshi Kaji; S Kamidono; Kazuo Chihara
Fasting increases the expression of basic fibroblast growth factor (FGF-2) messenger ribonucleic acid in rat hypothalamus.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1995;27(8):363-6.
1995: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; M Fukase; Kazuo Chihara
Carboxyl-terminal peptides from parathyroid hormone-related protein stimulate osteoclast-like cell formation.
Endocrinology 1995;136(3):842-8.
1995: H Kaji; Y Xu; Y Takahashi; H Abe; Norihiko Tamaki; Kazuo Chihara
Human TRH receptor messenger ribonucleic acid levels in normal and adenomatous pituitary: analysis by the competitive reverse transcription polymerase chain reaction method.
Clinical endocrinology 1995;42(3):243-8.
1995: T Yamaguchi; M Fukase; Toshitsugu Sugimoto; Kazuo Chihara
Hydrolysis of a carboxy-terminal fragment of parathyroid hormone-related protein by rat kidney: evidence for a crucial role of meprin.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1995;27(3):131-6.
1995: Y Matsumori; N Katakami; M Ito; Tadatsugu Taniguchi; N Iwata; T Takaishi; Kazuo Chihara; Toshimitsu Matsui
Cholecystokinin-B/gastrin receptor: a novel molecular probe for human small cell lung cancer.
Cancer research 1995;55(2):276-9.
1995: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; M Fukase; Masayoshi Kumegawa; Kazuo Chihara
Retinoic acid induces osteoclast-like cell formation by directly acting on hemopoietic blast cells and stimulates osteopontin mRNA expression in isolated osteoclasts.
Life sciences 1995;56(22):1903-13.
1995: Toshitsugu Sugimoto; Kazuo Chihara
Signal transduction mechanisms of parathyroid hormone- and parathyroid hormone-related-peptide-stimulated osteoclast-like cell formation from hemopoietic blast cells.
Mineral and electrolyte metabolism 1995;21(1-3):161-5.
1995: S Ohashi; Hiroshi Kaji; H Abe; Kazuo Chihara
Effect of fasting and growth hormone (GH) administration on GH receptor (GHR) messenger ribonucleic acid (mRNA) and GH-binding protein (GHBP) mRNA levels in male rats.
Life sciences 1995;57(18):1655-66.
1994: A Miyauchi; Y Kuroki; M Fukase; Tsuyoshi Fujita; Kazuo Chihara; Shunichi Shiozawa
Persistent expression of proto-oncogene c-fos stimulates osteoclast differentiation.
Biochemical and biophysical research communications 1994;205(3):1547-55.
1994: T Natazuka; T Yamaguchi; T Murayama; M Fukase; Toshimitsu Matsui; T Isobe; Kazuo Chihara
Chronic myelomonocytic leukemia following prolonged alkylating agent therapy for multiple myeloma.
International journal of hematology 1994;60(4):263-5.
1994: Masanori Kanatani; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
Role of interleukin-6 and prostaglandins in the effect of monocyte-conditioned medium on osteoclast formation.
The American journal of physiology 1994;267(6 Pt 1):E868-76.
1994: M Arao; T Yamaguchi; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
Involvement of protein kinase C in the stimulation of sodium-dependent phosphate transport by parathyroid hormone in osteoblast-like cells.
European journal of endocrinology / European Federation of Endocrine Societies 1994;131(6):646-51.
1994: T Sakuma; T Yamaguchi; H Abe; Fumio Kanda; Keisuke Hanioka; Katsuya Hisano; H Ito; M Okada; Kazuo Chihara
Adrenogenital syndrome caused by an androgen-producing adrenocortical tumor.
Internal medicine (Tokyo, Japan) 1994;33(12):790-4.
1994: T Yamaguchi; M Fukase; Toshitsugu Sugimoto; H Kido; Kazuo Chihara
Purification of meprin from human kidney and its role in parathyroid hormone degradation.
Biological chemistry Hoppe-Seyler 1994;375(12):821-4.
1994: T Natazuka; Y Manabe; M Kono; T Murayama; Toshimitsu Matsui; Kazuo Chihara
Association between non-insulin dependent diabetes mellitus and non-Hodgkin's lymphoma.
BMJ (Clinical research ed.) 1994;309(6964):1269.
1994: J Kano; Toshitsugu Sugimoto; Masanori Kanatani; Y Kuroki; T Tsukamoto; M Fukase; Kazuo Chihara
Second messenger signaling of c-fos gene induction by parathyroid hormone (PTH) and PTH-related peptide in osteoblastic osteosarcoma cells: its role in osteoblast proliferation and osteoclast-like cell formation.
Journal of cellular physiology 1994;161(2):358-66.
1994: M Asahara; Yoshikazu Kinoshita; H Nakata; Yumi Matsushima; Y Naribayashi; A Nakamura; Toshimitsu Matsui; Kazuo Chihara; J Yamamoto; A Ichikawa
Gastrin receptor genes are expressed in gastric parietal and enterochromaffin-like cells of Mastomys natalensis.
Digestive diseases and sciences 1994;39(10):2149-56.
1994: M Ito; N Iwata; Tadatsugu Taniguchi; T Murayama; Kazuo Chihara; Toshimitsu Matsui
Functional characterization of two cholecystokinin-B/gastrin receptor isoforms: a preferential splice donor site in the human receptor gene.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(10):1127-35.
1994: T Takaishi; Toshimitsu Matsui; T Tsukamoto; M Ito; T Taniguchi; M Fukase; Kazuo Chihara
TGF-beta-induced macrophage colony-stimulating factor gene expression in various mesenchymal cell lines.
The American journal of physiology 1994;267(1 Pt 1):C25-31.
1994: Hiroshi Kaji; S Ohashi; H Abe; Kazuo Chihara
Regulation of the growth hormone (GH) receptor and GH-binding protein mRNA.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1994;206(3):257-62.
1994: Hiroshi Kaji; Toshitsugu Sugimoto; A Miyauchi; M Fukase; K Tezuka; Yoshiyuki Hakeda; Masayoshi Kumegawa; Kazuo Chihara
Calcitonin inhibits osteopontin mRNA expression in isolated rabbit osteoclasts.
Endocrinology 1994;135(1):484-7.
1994: Toshitsugu Sugimoto; Masanori Kanatani; J Kano; T Kobayashi; T Yamaguchi; M Fukase; Kazuo Chihara
IGF-I mediates the stimulatory effect of high calcium concentration on osteoblastic cell proliferation.
The American journal of physiology 1994;266(5 Pt 1):E709-16.
1994: T Uchiyama; Hiroshi Kaji; H Abe; Kazuo Chihara
Negative regulation of hypothalamic growth hormone-releasing factor messenger ribonucleic acid by growth hormone and insulin-like growth factor I.
Neuroendocrinology 1994;59(5):441-50.
1994: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; A Miyauchi; T Kimura; S Sakakibara; M Fukase; Kazuo Chihara
Carboxyl-terminal parathyroid hormone fragments stimulate osteoclast-like cell formation and osteoclastic activity.
Endocrinology 1994;134(4):1897-904.
1994: M Arao; T Yamaguchi; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
Protein kinase C is crucial for the stimulation of sodium-dependent phosphate transport by parathyroid hormone-related peptide in osteoblast-like cells.
Biochemical and biophysical research communications 1994;199(3):1216-22.
1994: Yasufumi Shigeyoshi; Hitoshi Okamura; T Inatomi; Toshimitsu Matsui; M Ito; Hiroshi Kaji; H Abe; H Nakata; Tsutomu Chiba; Kazuo Chihara
Distribution of mRNA for CCK-B receptor in the brain of Mastomys natalensis: abundant expression in telencephalic neurons.
Brain research 1994;640(1-2):81-92.
1994: T Kobayashi; Toshitsugu Sugimoto; K Saijoh; M Fukase; Kazuo Chihara
Calcitonin directly acts on mouse osteoblastic MC3T3-E1 cells to stimulate mRNA expression of c-fos, insulin-like growth factor-1 and osteoblastic phenotypes (type 1 collagen and osteocalcin).
Biochemical and biophysical research communications 1994;199(2):876-80.
1994: Tadatsugu Taniguchi; Toshimitsu Matsui; M Ito; T Murayama; T Tsukamoto; Y Katakami; Tsutomu Chiba; Kazuo Chihara
Cholecystokinin-B/gastrin receptor signaling pathway involves tyrosine phosphorylations of p125FAK and p42MAP.
Oncogene 1994;9(3):861-7.
1994: T Yamaguchi; H Abe; T Matsui; H Kaji; M Fukase; Norihiko Tamaki; Kazuo Chihara
Lymphocytic hypophysitis, pustulosis palmaris et plantaris and eosinophilia.
Internal medicine (Tokyo, Japan) 1994;33(3):150-4.
1994: M Arao; T Yamaguchi; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
Characterization of a chymotrypsin-like hydrolytic activity in the opossum kidney cell.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1994;72(3-4):157-62.
1994: J Kano; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
Direct involvement of cAMP-dependent protein kinase in the regulation of alkaline phosphatase activity by parathyroid hormone (PTH) and PTH-related peptide in osteoblastic UMR-106 cells.
Biochemical and biophysical research communications 1994;199(1):271-6.
1994: M Ito; Toshimitsu Matsui; T Taniguchi; Kazuo Chihara
Alternative splicing generates two distinct transcripts for the Drosophila melanogaster fibroblast growth factor receptor homolog.
Gene 1994;139(2):215-8.
1994: T Tsukamoto; Toshimitsu Matsui; T Takaishi; M Ito; M Fukase; Kazuo Chihara
Retinoic acid differentially affects platelet-derived growth factor and epidermal growth factor-regulated cell growth of mouse osteoblast-like cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(2):207-12.
1994: Toshitsugu Sugimoto; K Ikeda; J Kano; T Yamaguchi; M Fukase; Kazuo Chihara
Cross-talk of parathyroid hormone-responsive dual signal transduction systems in osteoblastic osteosarcoma cells: its role in PTH-induced homologous desensitization of intracellular calcium response.
Journal of cellular physiology 1994;158(2):374-80.
1994: T Yamaguchi; M Fukase; H Kido; Toshitsugu Sugimoto; N Katunuma; Kazuo Chihara
Meprin is predominantly involved in parathyroid hormone degradation by the microvillar membranes of rat kidney.
Life sciences 1994;54(5):381-6.
1994: Kazuo Chihara; T Uchiyama; S Shakutsui; Hiroshi Kaji; Yasuhiko Okimura; H Abe
Molecular genetics of growth hormone-releasing factors.
Hormone research 1994;42(4-5):182-8.
1994: T Yamaguchi; H Abe; T Kuwano; T Sugimoto; Kazuo Chihara
Congenital adrenal hyperplasia with 47, XXY Klinefelter syndrome.
Experimental and clinical endocrinology 1994;102(4):348-50.
1994: K Yoshimura; Hiroshi Kaji; S Kamidono; Kazuo Chihara
Expression of basic fibroblast growth factor (FGF-2) messenger ribonucleic acid is regulated by testosterone in the rat anterior pituitary.
Growth factors (Chur, Switzerland) 1994;10(4):253-8.
1993: Toshitsugu Sugimoto; Masanori Kanatani; J Kano; Hiroshi Kaji; T Tsukamoto; T Yamaguchi; M Fukase; Kazuo Chihara
Effects of high calcium concentration on the functions and interactions of osteoblastic cells and monocytes and on the formation of osteoclast-like cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1993;8(12):1445-52.
1993: Toshitsugu Sugimoto; J Kano; T Yamaguchi; M Fukase; Kazuo Chihara
Role of calcium/protein kinase C in the regulation of DNA synthesis by parathyroid hormone-related peptide in osteoblastic osteosarcoma cells.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1993;25(12):608-11.
1993: Toshimitsu Matsui; Kimihiko Sano; T Tsukamoto; M Ito; T Takaishi; H Nakata; H Nakamura; Kazuo Chihara
Human neuroblastoma cells express alpha and beta platelet-derived growth factor receptors coupling with neurotrophic and chemotactic signaling.
The Journal of clinical investigation 1993;92(3):1153-60.
1993: Toshitsugu Sugimoto; Masanori Kanatani; Hiroshi Kaji; T Yamaguchi; M Fukase; Kazuo Chihara
Second messenger signaling of PTH- and PTHRP-stimulated osteoclast-like cell formation from hemopoietic blast cells.
The American journal of physiology 1993;265(3 Pt 1):E367-73.
1993: M Ito; Toshimitsu Matsui; Tadatsugu Taniguchi; T Tsukamoto; T Murayama; N Arima; H Nakata; Tsutomu Chiba; Kazuo Chihara
Functional characterization of a human brain cholecystokinin-B receptor. A trophic effect of cholecystokinin and gastrin.
The Journal of biological chemistry 1993;268(24):18300-5.
1993: Hiroshi Kaji; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
Role of dual signal transduction systems in the stimulation of bone resorption by parathyroid hormone-related peptide. The direct involvement of cAMP-dependent protein kinase.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1993;25(8):421-4.
1993: M Yasuda; N Minamitani; Kiyoshi Maeda; Kazuo Chihara; K Fujita; I Kobayashi
Peptide histidine methionine and vasoactive intestinal peptide levels in human cerebrospinal fluid: age-related changes and absence of a correlation with serum prolactin.
Regulatory peptides 1993;46(3):565-73.
1993: Hiroshi Kaji; Toshitsugu Sugimoto; Masanori Kanatani; M Fukase; Kazuo Chihara
Involvement of dual signal transduction systems in the stimulation of osteoclast-like cell formation by parathyroid hormone and parathyroid hormone-related peptide.
Biochemical and biophysical research communications 1993;194(1):157-62.
1993: S Ohashi; Hiroshi Kaji; H Abe; Kazuo Chihara
"Paradoxical" GH suppression by secretagogues in acromegaly?
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1993;25(7):393-4.
1993: C Nakamoto; H Baba; M Fukase; K Nakajima; T Kimura; S Sakakibara; Tsuyoshi Fujita; Kazuo Chihara
Individual and combined effects of intact PTH, amino-terminal, and a series of truncated carboxyl-terminal PTH fragments on alkaline phosphatase activity in dexamethasone-treated rat osteoblastic osteosarcoma cells, ROS 17/2.8.
Acta endocrinologica 1993;128(4):367-72.
1993: Toshitsugu Sugimoto; J Kano; K Ikeda; M Fukase; Kazuo Chihara
Interaction of parathyroid hormone-related peptide-responsive dual signal transduction systems in osteoblastic osteosarcoma cells: role in PTHrP-induced homologous desensitization.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1993;8(4):451-8.
1993: H Kaji; Y Takahashi; Kazuo Chihara
The regional distribution of thyrotropin-releasing hormone receptor messenger ribonucleic acid in the brain.
Neuroscience letters 1993;151(1):81-4.
1993: J Kano; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
Cross talk of dual-signal transduction systems in the regulation of DNA synthesis by parathyroid hormone in osteoblastic osteosarcoma cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1993;8(3):323-9.
1993: Masanori Kanatani; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
Effect of 1,25-dihydroxyvitamin D3 on the proliferation of osteoblastic MC3T3-E1 cells by modulating the release of local regulators from monocytes.
Biochemical and biophysical research communications 1993;190(2):529-35.
1992: Riko Kitazawa; Sohei Kitazawa; M Fukase; Tsuyoshi Fujita; A Kobayashi; Kazuo Chihara; Sakan Maeda
The expression of parathyroid hormone-related protein (PTHrP) in normal parathyroid: histochemistry and in situ hybridization.
Histochemistry 1992;98(4):211-5.
1992: H Nakata; Toshimitsu Matsui; M Ito; Tadatsugu Taniguchi; Y Naribayashi; N Arima; A Nakamura; Yoshikazu Kinoshita; Kazuo Chihara; S Hosoda
Cloning and characterization of gastrin receptor from ECL carcinoid tumor of Mastomys natalensis.
Biochemical and biophysical research communications 1992;187(2):1151-7.
1992: T Yamaguchi; M Fukase; M Arao; Toshitsugu Sugimoto; Kazuo Chihara
Endothelin 1 hydrolysis by rat kidney membranes.
FEBS letters 1992;309(3):303-6.
1992: J Kano; Toshitsugu Sugimoto; M Fukase; Kazuo Chihara
The direct involvement of cAMP-dependent protein kinase in the regulation of collagen synthesis by parathyroid hormone (PTH) and PTH-related peptide in osteoblast-like osteosarcoma cells (UMR-106).
Biochemical and biophysical research communications 1992;184(1):525-9.
1991: Akio Inui; M Okita; M Nakajima; T Inoue; N Sakatani; M Oya; H Morioka; Yasuhiko Okimura; Kazuo Chihara; S Baba
Neuropeptide regulation of feeding in dogs.
The American journal of physiology 1991;261(3 Pt 2):R588-94.
1991: S Hayashi; Yasuhiko Okimura; H Yagi; T Uchiyama; Y Takeshima; S Shakutsui; S Oohashi; C Y Bowers; Kazuo Chihara
Intranasal administration of His-D-Trp-Ala-Trp-D-Phe-LysNH2 (growth hormone releasing peptide) increased plasma growth hormone and insulin-like growth factor-I levels in normal men.
Endocrinologia japonica 1991;38(1):15-21.
1990: Akio Inui; T Inoue; M Nakajima; M Okita; N Sakatani; Yasuhiko Okimura; Kazuo Chihara; S Baba
Brain neuropeptide Y in the control of adrenocorticotropic hormone secretion in the dog.
Brain research 1990;510(2):211-5.
1990: A Yamaguchi; Tsutomu Chiba; T Morishita; A Nakamura; T Inui; T Yamatani; S Kadowaki; Kazuo Chihara; M Fukase; Tsuyoshi Fujita
Calcitonin gene-related peptide and induction of hyperglycemia in conscious rats in vivo.
Diabetes 1990;39(2):168-74.
1990: N Kitajima; Kazuo Chihara; H Abe; Yasuhiko Okimura; S Shakutsui
Galanin stimulates immunoreactive growth hormone-releasing factor secretion from rat hypothalamic slices perifused in vitro.
Life sciences 1990;47(25):2371-6.
1989: N Minamitani; Kazuo Chihara; Hiroshi Kaji; H Kodama; T Kita; Tsuyoshi Fujita
Alpha 2-adrenergic control of growth hormone (GH) secretion in conscious male rabbits: involvement of endogenous GH-releasing factor and somatostatin.
Endocrinology 1989;125(6):2839-45.
1989: Kazuo Chihara
Growth hormone--physiological roles of endogenous GRF and somatostatin in its regulation.
Japanese journal of medicine 1989;28(6):788-9.
1989: Kenji Jinnai; Kazuo Chihara; Fumio Kanda; K Tada; Tsuyoshi Fujita
Calcitonin gene-related peptide enhances spontaneous acetylcholine release from the rat motor nerve terminal.
Neuroscience letters 1989;103(1):64-8.
1989: M Sato; Kazuo Chihara; T Kita; Y Kashio; Yasuhiko Okimura; N Kitajima; Tsuyoshi Fujita
Physiological role of somatostatin-mediated autofeedback regulation for growth hormone: importance of growth hormone in triggering somatostatin release during a trough period of pulsatile growth hormone release in conscious male rats.
Neuroendocrinology 1989;50(2):139-51.
1989: Yasuhiko Okimura; N Kitajima; T Uchiyama; H Yagi; H Abe; S Shakutsui; Kazuo Chihara
Insulin-like growth factor I (IGF-I) production and the presence of IGF-I receptors in rat medullary thyroid carcinoma cell line 6-23 (clone 6).
Biochemical and biophysical research communications 1989;161(2):589-95.
1989: N Minamitani; Kazuo Chihara; Hiroshi Kaji; H Kodama; T Kita; Tsuyoshi Fujita
Ultradian rhythm of growth hormone secretion in unrestrained, conscious male rabbits: role of endogenous somatostatintdagger.
Journal of neuroendocrinology 1989;1(2):147-51.
1989: S Shakutsui; H Abe; Kazuo Chihara
GHRH treatment: studies in an animal model.
Acta paediatrica Scandinavica. Supplement 1989;349():101-7; discussion 108.
1989: T Inui; Tsutomu Chiba; Yasuhiko Okimura; T Morishita; A Nakamura; A Yamaguchi; T Yamatani; S Kadowaki; Kazuo Chihara; Tsuyoshi Fujita
Presence and release of calcitonin gene-related peptide in rat stomach.
Life sciences 1989;45(13):1199-206.
1989: N Kitajima; Kazuo Chihara; H Abe; Yasuhiko Okimura; Y Fujii; M Sato; S Shakutsui; M Watanabe; Tsuyoshi Fujita
Effects of dopamine on immunoreactive growth hormone-releasing factor and somatostatin secretion from rat hypothalamic slices perifused in vitro.
Endocrinology 1989;124(1):69-76.
1988: Yasuhiko Okimura; Kazuo Chihara; T Kita; Y Kashio; M Sato; N Kitajima; H Abe; Kentaro Takahashi; Tsuyoshi Fujita
Discordance between growth hormone (GH) responses after GH-releasing hormone and insulin hypoglycemia in myotonic dystrophy.
The Journal of clinical endocrinology and metabolism 1988;67(5):1074-9.
1988: Koji Takano; Naomi Hizuka; K Asakawa; Kazuo Chihara; K Sanayama; K Shizume
Human growth hormone-releasing hormone (hGH-RH; hGRF) treatment of four patients with GH deficiency.
Endocrinologia japonica 1988;35(5):775-81.
1988: Tsutomu Chiba; Yasuhiko Okimura; H Kodama; S Kadowaki; Kazuo Chihara; Tsuyoshi Fujita
Tolbutamide inhibits gastrin release in man.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1988;20(10):641-4.
1987: T Kita; Kazuo Chihara; Y Kashio; Yasuhiko Okimura; M Sato; N Kitajima; Tsuyoshi Fujita
The effect of hypothalamic deafferentation on rat growth hormone-releasing factor (rGRF)-like immunoreactivity content in the medial basal hypothalamus of rats.
Endocrinologia japonica 1987;34(3):423-6.
1986: T Yamatani; S Kadowaki; Tsutomu Chiba; H Abe; Kazuo Chihara; M Fukase; Tsuyoshi Fujita
Calcitonin gene-related peptide stimulates somatostatin release from isolated perfused rat stomach.
Endocrinology 1986;118(5):2144-5.
1985: T Yamatani; S Kadowaki; Tsutomu Chiba; Kazuo Chihara; M Fukase; Tsuyoshi Fujita
12-O-tetradecanoyl phorbol-13-acetate (TPA) stimulates somatostatin release from isolated perfused rat stomach.
Life sciences 1985;37(25):2415-9.