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Robert Childs

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Carbohydrate Sequence

Concepts & Ideas

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Publications

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Jan Marchant; Jean-Baptiste Marq; Camila Pinzan; Maria Cristina Roque Barreira; Savvas Saouros; Kovilen Sawmynaden; Peter Simpson; Dominique Soldati-Favre; Wengang Chai; Robert A Childs; Ben Cowper; Ten Feizi; Nikolas Friedrich; Livia Lai; Lloyd Liew; Yan Liu; Stephen Matthews
Galactose recognition by the apicomplexan parasite Toxoplasma gondii.
Angelina S Palma; Yibing Zhang; María Asunción Campanero-Rhodes; Robert A Childs; Ten Feizi; Yan Liu; Wengang Chai
Neoglycolipid-based "designer" oligosaccharide microarrays to define β-glucan ligands for Dectin-1.
Yan Liu; Angelina S Palma; Mark S Stoll; María Asunción Campanero-Rhodes; Wengang Chai; Robert A Childs; Ten Feizi
Neoglycolipid-based oligosaccharide microarray system: preparation of NGLs and their noncovalent immobilization on nitrocellulose-coated glass slides for microarray analyses.

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All Publications

2012: Jan Marchant; Jean-Baptiste Marq; Camila Pinzan; Maria Cristina Roque Barreira; Savvas Saouros; Kovilen Sawmynaden; Peter Simpson; Dominique Soldati-Favre; Wengang Chai; Robert A Childs; Ben Cowper; Ten Feizi; Nikolas Friedrich; Livia Lai; Lloyd Liew; Yan Liu; Stephen Matthews
Galactose recognition by the apicomplexan parasite Toxoplasma gondii.
The Journal of biological chemistry 2012;287(20):16720-33.
2012: Angelina S Palma; Yibing Zhang; María Asunción Campanero-Rhodes; Robert A Childs; Ten Feizi; Yan Liu; Wengang Chai
Neoglycolipid-based "designer" oligosaccharide microarrays to define β-glucan ligands for Dectin-1.
Methods in molecular biology (Clifton, N.J.) 2012;808():337-59.
2012: Yan Liu; Angelina S Palma; Mark S Stoll; María Asunción Campanero-Rhodes; Wengang Chai; Robert A Childs; Ten Feizi
Neoglycolipid-based oligosaccharide microarray system: preparation of NGLs and their noncovalent immobilization on nitrocellulose-coated glass slides for microarray analyses.
Methods in molecular biology (Clifton, N.J.) 2012;808():117-36.
2007: María Asunción Campanero-Rhodes; Alicia Smith; Wengang Chai; Sandro Sonnino; Laura Mauri; Robert A Childs; Yibing Zhang; Helge Ewers; Ari Helenius; Anne Imberty; Ten Feizi
N-glycolyl GM1 ganglioside as a receptor for simian virus 40.
Journal of virology 2007;81(23):12846-58.
2007: Yan Liu; Ten Feizi; María Asunción Campanero-Rhodes; Robert A Childs; Yibing Zhang; Barbara Mulloy; Philip G Evans; Helen M I Osborn; Diana Otto; Paul R Crocker; Wengang Chai
Neoglycolipid probes prepared via oxime ligation for microarray analysis of oligosaccharide-protein interactions.
Chemistry & biology 2007;14(7):847-59.
2007: Tharin M A Blumenschein; Nikolas Friedrich; Robert A Childs; Savvas Saouros; Elisabeth P Carpenter; María Asunción Campanero-Rhodes; Pete Simpson; Wengang Chai; Theodoros Koutroukides; Michael J Blackman; Ten Feizi; Dominique Soldati-Favre; Stephen Matthews
Atomic resolution insight into host cell recognition by Toxoplasma gondii.
The EMBO journal 2007;26(11):2808-20.
2006: María Asunción Campanero-Rhodes; Robert A Childs; Makoto Kiso; Shiro Komba; Christine Le Narvor; Joanna Warren; Diana Otto; Paul R Crocker; Ten Feizi
Carbohydrate microarrays reveal sulphation as a modulator of siglec binding.
Biochemical and biophysical research communications 2006;344(4):1141-6.
2006: Yan Liu; Wengang Chai; Robert A Childs; Ten Feizi
Preparation of neoglycolipids with ring-closed cores via chemoselective oxime-ligation for microarray analysis of carbohydrate-protein interactions.
Methods in enzymology 2006;415():326-40.
2004: Sreelatha T Reddy; Wengang Chai; Robert A Childs; Jimmy D Page; Ten Feizi; Nancy M Dahms
Identification of a low affinity mannose 6-phosphate-binding site in domain 5 of the cation-independent mannose 6-phosphate receptor.
The Journal of biological chemistry 2004;279(37):38658-67.
2002: Christine Galustian; Robert A Childs; Mark Stoll; Hideharu Ishida; Makoto Kiso; Ten Feizi
Synergistic interactions of the two classes of ligand, sialyl-Lewis(a/x) fuco-oligosaccharides and short sulpho-motifs, with the P- and L-selectins: implications for therapeutic inhibitor designs.
Immunology 2002;105(3):350-9.
1999: Robert A Childs; Christine Galustian; Alexander M Lawson; G Dougan; K Benwell; G Frankel; Ten Feizi
Recombinant soluble human CD69 dimer produced in Escherichia coli: reevaluation of saccharide binding.
Biochemical and biophysical research communications 1999;266(1):19-23.
1999: Christine Leteux; Mark S Stoll; Robert A Childs; Wengang Chai; M Vorozhaikina; Ten Feizi
Influence of oligosaccharide presentation on the interactions of carbohydrate sequence-specific antibodies and the selectins. Observations with biotinylated oligosaccharides.
Journal of immunological methods 1999;227(1-2):109-19.
1999: U Bierfreund; Thorsten Lemm; A Hoffmann; G Uhlhorn-Dierks; Robert A Childs; CT Yuen; Ten Feizi; Konrad Sandhoff
Recombinant GM2-activator protein stimulates in vivo degradation of GA2 in GM2 gangliosidosis AB variant fibroblasts but exhibits no detectable binding of GA2 in an in vitro assay.
Neurochemical research 1999;24(2):295-300.
1998: Christine Leteux; Robert A Childs; Wengang Chai; Mark S Stoll; Heide Kogelberg; Ten Feizi
Biotinyl-l-3-(2-naphthyl)-alanine hydrazide derivatives of N-glycans: versatile solid-phase probes for carbohydrate-recognition studies.
Glycobiology 1998;8(3):227-36.
1997: Christine Galustian; Robert A Childs; CT Yuen; A Hasegawa; Makoto Kiso; André Lubineau; G Shaw; Ten Feizi
Valency dependent patterns of binding of human L-selectin toward sialyl and sulfated oligosaccharides of Le(a) and Le(x) types: relevance to anti-adhesion therapeutics.
Biochemistry 1997;36(17):5260-6.
1995: P J Green; CT Yuen; Robert A Childs; Wengang Chai; M Miyasaka; R Lemoine; André Lubineau; B Smith; H Ueno; K C Nicolaou
Further studies of the binding specificity of the leukocyte adhesion molecule, L-selectin, towards sulphated oligosaccharides--suggestion of a link between the selectin- and the integrin-mediated lymphocyte adhesion systems.
Glycobiology 1995;5(1):29-38.
1994: Karel Bezouska; CT Yuen; J O'Brien; Robert A Childs; Wengang Chai; Alexander M Lawson; K Drbal; Anna Fiserová; M Pospísil; Ten Feizi
Oligosaccharide ligands for NKR-P1 protein activate NK cells and cytotoxicity.
Nature 1994;372(6502):150-7.
1994: Ten Feizi; Robert A Childs; Heide Kogelberg
The new biology of carbohydrates.
Glycobiology 1994;4(2):106-9.
1994: Ten Feizi; Robert A Childs
Neoglycolipids: probes in structure/function assignments to oligosaccharides.
Methods in enzymology 1994;242():205-17.
1992: M Larkin; T J Ahern; M S Stoll; M Shaffer; D Sako; J O'Brien; CT Yuen; Alexander M Lawson; Robert A Childs; K M Barone
Spectrum of sialylated and nonsialylated fuco-oligosaccharides bound by the endothelial-leukocyte adhesion molecule E-selectin. Dependence of the carbohydrate binding activity on E-selectin density.
The Journal of biological chemistry 1992;267(19):13661-8.
1992: Robert A Childs; J R Wright; G F Ross; CT Yuen; Alexander M Lawson; Wengang Chai; Kurt Drickamer; Ten Feizi
Specificity of lung surfactant protein SP-A for both the carbohydrate and the lipid moieties of certain neutral glycolipids.
The Journal of biological chemistry 1992;267(14):9972-9.
1991: J C Solomon; M S Stoll; P Penfold; W M Abbott; Robert A Childs; P Hanfland; Ten Feizi
Studies of the binding specificity of the soluble 14,000-dalton bovine heart muscle lectin using immobilised glycolipids and neoglycolipids.
Carbohydrate research 1991;213():293-307.
1990: Robert A Childs; Ten Feizi; CT Yuen; Kurt Drickamer; M S Quesenberry
Differential recognition of core and terminal portions of oligosaccharide ligands by carbohydrate-recognition domains of two mannose-binding proteins.
The Journal of biological chemistry 1990;265(34):20770-7.
1989: M Larkin; Robert A Childs; T J Matthews; S Thiel; T Mizuochi; Alexander M Lawson; J S Savill; C Haslett; R Diaz; Ten Feizi
Oligosaccharide-mediated interactions of the envelope glycoprotein gp120 of HIV-1 that are independent of CD4 recognition.
AIDS (London, England) 1989;3(12):793-8.
1989: T Mizuochi; RW Loveless; Alexander M Lawson; Wengang Chai; Peter Lachmann; Robert A Childs; S Thiel; Ten Feizi
A library of oligosaccharide probes (neoglycolipids) from N-glycosylated proteins reveals that conglutinin binds to certain complex-type as well as high mannose-type oligosaccharide chains.
The Journal of biological chemistry 1989;264(23):13834-9.
1989: RW Loveless; Ten Feizi; Robert A Childs; T Mizuochi; M S Stoll; R G Oldroyd; Peter Lachmann
Bovine serum conglutinin is a lectin which binds non-reducing terminal N-acetylglucosamine, mannose and fucose residues.
The Biochemical journal 1989;258(1):109-13.
1988: I J Rosenstein; M S Stoll; T Mizuochi; Robert A Childs; Elizabeth F Hounsell; Ten Feizi
New type of adhesive specificity revealed by oligosaccharide probes in Escherichia coli from patients with urinary tract infection.
Lancet 1988;2(8624):1327-30.
1988: M S Stoll; T Mizuochi; Robert A Childs; Ten Feizi
Improved procedure for the construction of neoglycolipids having antigenic and lectin-binding activities, from reducing oligosaccharides.
The Biochemical journal 1988;256(2):661-4.
1983: K Uemura; Robert A Childs; P Hanfland; Ten Feizi
A multiplicity of erythrocyte glycolipids of the neolacto series revealed by immuno-thin-layer chromatography with monoclonal anti-I and anti-i antibodies.
Bioscience reports 1983;3(6):577-88.