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Ashutosh Chilkoti

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Trine Christensen; Wafa Hassouneh; Kimberley Trabbic-Carlson; Ashutosh Chilkoti
Predicting transition temperatures of elastin-like polypeptide fusion proteins.
Joseph J Bellucci; Jayanta Bhattacharyya; Miriam Amiram; Dewey G McCafferty; Ashutosh Chilkoti
Three-in-one chromatography-free purification, tag removal, and site-specific modification of recombinant fusion proteins using sortase A and elastin-like polypeptides.
Miriam Amiram; Mark N Feinglos; Xinghai Li; Kelli M Luginbuhl; Ashutosh Chilkoti
Injectable protease-operated depots of glucagon-like peptide-1 provide extended and tunable glucose control.

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All Publications

2013: Trine Christensen; Wafa Hassouneh; Kimberley Trabbic-Carlson; Ashutosh Chilkoti
Predicting transition temperatures of elastin-like polypeptide fusion proteins.
Biomacromolecules 2013;14(5):1514-9.
2013: Joseph J Bellucci; Jayanta Bhattacharyya; Miriam Amiram; Dewey G McCafferty; Ashutosh Chilkoti
Three-in-one chromatography-free purification, tag removal, and site-specific modification of recombinant fusion proteins using sortase A and elastin-like polypeptides.
Angewandte Chemie (International ed. in English) 2013;52(13):3703-8.
2013: Miriam Amiram; Mark N Feinglos; Xinghai Li; Kelli M Luginbuhl; Ashutosh Chilkoti
Injectable protease-operated depots of glucagon-like peptide-1 provide extended and tunable glucose control.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(8):2792-7.
2013: Jonathan R McDaniel; Kevin B Vargo; Jayanta Bhattacharyya; Daniel A Hammer; Wafa Hassouneh; Ashutosh Chilkoti
Self-assembly of thermally responsive nanoparticles of a genetically encoded peptide polymer by drug conjugation.
Angewandte Chemie (International ed. in English) 2013;52(6):1683-7.
2013: Vinalia Tjong; Hua Yu; Angus Hucknall; Ashutosh Chilkoti
Direct fluorescence detection of RNA on microarrays by surface-initiated enzymatic polymerization.
Analytical chemistry 2013;85(1):426-33.
2013: Arjun Thapa; Robin H Simons; Eva Y Chi; Ashutosh Chilkoti; Wei Han; Gabriel P López
Effect of detergents on the thermal behavior of elastin-like polypeptides.
Biopolymers 2013;99(1):55-62.
2013: Sarah R MacEwan; Ashutosh Chilkoti
Harnessing the power of cell-penetrating peptides: activatable carriers for targeting systemic delivery of cancer therapeutics and imaging agents.
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 2013;5(1):31-48.
2012: Antoine Moreau; Qiang Wang; Benjamin J Wiley; Ashutosh Chilkoti; Cristian Ciracì; Ryan T Hill; Jack J Mock; David R Smith
Controlled-reflectance surfaces with film-coupled colloidal nanoantennas.
Nature 2012;492(7427):86-9.
2012: Wenge Liu; Jonathan McDaniel; Ji Sun Park; Felipe Garcia Quiroz; Jeffery Schaal; Michael Zalutsky; Daisuke Asai; Xinghai Li; Ashutosh Chilkoti
Brachytherapy using injectable seeds that are self-assembled from genetically encoded polypeptides in situ.
Cancer research 2012;72(22):5956-65.
2012: Ashley A Manzoor; David Needham; Ji-Young Park; Won Park; Andrew J Simnick; Timo L M ten Hagen; Matthew R Dreher; Gabi Hanna; Gerben A Koning; Chelsea D Landon; Lars H Lindner; Ashutosh Chilkoti; Shiva Das; Mark W Dewhirst
Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors.
Cancer research 2012;72(21):5566-75.
2012: Ryan T Hill; Angus Hucknall; Nan M Jokerst; Jack J Mock; David R Smith; Scott D Wolter; Ashutosh Chilkoti
Plasmon ruler with angstrom length resolution.
ACS nano 2012;6(10):9237-46.
2012: M Nuruzzaman Khan; Vinalia Tjong; Ashutosh Chilkoti; Michael Zharnikov
Fabrication of ssDNA/oligo(ethylene glycol) monolayers and complex nanostructures by an irradiation-promoted exchange reaction.
Angewandte Chemie (International ed. in English) 2012;51(41):10303-6.
2012: Kevin W H Kwok; Jie Liu; Stella M Marinakos; Clay M Nelson; Mark R Wiesner; Melanie Auffan; Appala R Badireddy; Ashutosh Chilkoti; David E Hinton
Uptake of silver nanoparticles and toxicity to early life stages of Japanese medaka (Oryzias latipes): effect of coating materials.
Aquatic toxicology (Amsterdam, Netherlands) 2012;120-121():59-66.
2012: C Ciracì; A I Fernández-Domínguez; R T Hill; S A Maier; JJ Mock; John Pendry; Ashutosh Chilkoti; Y Urzhumov; David R Smith
Probing the ultimate limits of plasmonic enhancement.
Science (New York, N.Y.) 2012;337(6098):1072-4.
2012: Donghua Xu; Daisuke Asai; Ashutosh Chilkoti; Stephen L Craig
Rheological properties of cysteine-containing elastin-like polypeptide solutions and hydrogels.
Biomacromolecules 2012;13(8):2315-21.
2012: Jeffrey A Hubbell; Ashutosh Chilkoti
Chemistry. Nanomaterials for drug delivery.
Science (New York, N.Y.) 2012;337(6092):303-5.
2012: Daisuke Asai; Daniel J Callahan; Stephen L Craig; Felipe Garcia Quiroz; Wenge Liu; Donghua Xu; Michael R Zalutsky; Ashutosh Chilkoti
Protein polymer hydrogels by in situ, rapid and reversible self-gelation.
Biomaterials 2012;33(21):5451-8.
2012: Sarah R Macewan; Ashutosh Chilkoti
Digital switching of local arginine density in a genetically encoded self-assembled polypeptide nanoparticle controls cellular uptake.
Nano letters 2012;12(6):3322-8.
2012: Wafa Hassouneh; Rihe Liu; Sarah R MacEwan; Manfred Schmidt; Robert Branscheid; Karl Fischer; Chuan Lawrence Fu; Ashutosh Chilkoti
Unexpected multivalent display of proteins by temperature triggered self-assembly of elastin-like polypeptide block copolymers.
Biomacromolecules 2012;13(5):1598-605.
2012: Jonathan R McDaniel; Mark Dewhirst; Sarah R Macewan; Ashutosh Chilkoti
Doxorubicin-conjugated chimeric polypeptide nanoparticles that respond to mild hyperthermia.
Journal of controlled release : official journal of the Controlled Release Society 2012;159(3):362-7.
2012: JJ Mock; Ashutosh Chilkoti; Ryan T Hill; Yu-Ju Tsai; David R Smith
Probing dynamically tunable localized surface plasmon resonances of film-coupled nanoparticles by evanescent wave excitation.
Nano letters 2012;12(4):1757-64.
2012: Daniel J Callahan; Matthew R Dreher; Wafa Hassouneh; Minkyu Kim; Xinghai Li; Wenge Liu; Piotr Marszalek; Ashutosh Chilkoti
Triple stimulus-responsive polypeptide nanoparticles that enhance intratumoral spatial distribution.
Nano letters 2012;12(4):2165-70.
2011: Robert Ferris; Angus Hucknall; Byung Seok Kwon; Tao Chen; Ashutosh Chilkoti; Stefan Zauscher
Field-induced nanolithography for patterning of non-fouling polymer brush surfaces.
Small (Weinheim an der Bergstrasse, Germany) 2011;7(21):3032-7.
2011: Kevin Seekell; Ashutosh Chilkoti; Matthew J Crow; Stella Marinakos; Julie Ostrander; Adam Wax
Hyperspectral molecular imaging of multiple receptors using immunolabeled plasmonic nanoparticles.
Journal of biomedical optics 2011;16(11):116003.
2011: Andrew J Simnick; Miriam Amiram; Mark W Dewhirst; Gabi Hanna; Christopher D Kontos; Wenge Liu; Ashutosh Chilkoti
In vivo tumor targeting by a NGR-decorated micelle of a recombinant diblock copolypeptide.
Journal of controlled release : official journal of the Controlled Release Society 2011;155(2):144-51.
2011: Gregory J Nusz; Srinath Rangarajan; Stella M Marinakos; Ashutosh Chilkoti
Dual-order snapshot spectral imaging of plasmonic nanoparticles.
Applied optics 2011;50(21):4198-206.
2011: Vinalia Tjong; Hua Yu; Angus Hucknall; Srinath Rangarajan; Ashutosh Chilkoti
Amplified on-chip fluorescence detection of DNA hybridization by surface-initiated enzymatic polymerization.
Analytical chemistry 2011;83(13):5153-9.
2011: Sabine Fluegel; Jasmin Buehler; Karl Fischer; Jonathan R McDaniel; Ashutosh Chilkoti; Manfred Schmidt
Self-assembly of monodisperse oligonucleotide-elastin block copolymers into stars and compound micelles.
Chemistry (Weinheim an der Bergstrasse, Germany) 2011;17(20):5503-6.
2011: Shah Alang Ahmad; Graham J Leggett; Angus Hucknall; Ashutosh Chilkoti
Micro- and nanostructured poly[oligo(ethylene glycol)methacrylate] brushes grown from photopatterned halogen initiators by atom transfer radical polymerization.
Biointerphases 2011;6(1):8-15.
2011: Peng Yang; Stella M Marinakos; Ashutosh Chilkoti
Spatially addressable chemoselective C-terminal ligation of an intein fusion protein from a complex mixture to a hydrazine-terminated surface.
Langmuir : the ACS journal of surfaces and colloids 2011;27(4):1463-71.
2011: Miriam Amiram; Felipe Garcia Quiroz; Daniel J Callahan; Ashutosh Chilkoti
A highly parallel method for synthesizing DNA repeats enables the discovery of 'smart' protein polymers.
Nature materials 2011;10(2):141-8.
2011: Matthew J Crow; Stella M Marinakos; J Michael Cook; Ashutosh Chilkoti; Adam Wax
Plasmonic flow cytometry by immunolabeled nanorods.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2011;79(1):57-65.
2011: Corin Williams; Xin Q Brown; Erzsebet Bartolak-Suki; Hongwei Ma; Ashutosh Chilkoti; Wong Wong
The use of micropatterning to control smooth muscle myosin heavy chain expression and limit the response to transforming growth factor β1 in vascular smooth muscle cells.
Biomaterials 2011;32(2):410-8.
2010: Jonathan R McDaniel; Daniel J Callahan; Ashutosh Chilkoti
Drug delivery to solid tumors by elastin-like polypeptides.
Advanced drug delivery reviews 2010;62(15):1456-67.
2010: Dana L Nettles; Ashutosh Chilkoti; Lori A Setton
Applications of elastin-like polypeptides in tissue engineering.
Advanced drug delivery reviews 2010;62(15):1479-85.
2010: Shiuan-Yeh Chen; Jack J Mock; Ryan T Hill; Ashutosh Chilkoti; David R Smith; Anne A Lazarides
Gold nanoparticles on polarizable surfaces as Raman scattering antennas.
ACS nano 2010;4(11):6535-46.
2010: Joel N Meyer; Christopher A Lord; Xinyu Y Yang; Elena A Turner; Appala R Badireddy; Stella M Marinakos; Ashutosh Chilkoti; Mark R Wiesner; Melanie Auffan
Intracellular uptake and associated toxicity of silver nanoparticles in Caenorhabditis elegans.
Aquatic toxicology (Amsterdam, Netherlands) 2010;100(2):140-50.
2010: Ryan T Hill; JJ Mock; Yaroslav Urzhumov; David S Sebba; Steven J Oldenburg; Shiuan-Yeh Chen; Anne A Lazarides; Ashutosh Chilkoti; David R Smith
Leveraging nanoscale plasmonic modes to achieve reproducible enhancement of light.
Nano letters 2010;10(10):4150-4.
2010: Weiping Gao; Wenge Liu; Trine Christensen; Michael R Zalutsky; Ashutosh Chilkoti
In situ growth of a PEG-like polymer from the C terminus of an intein fusion protein improves pharmacokinetics and tumor accumulation.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(38):16432-7.
2010: Wafa Hassouneh; Trine Christensen; Ashutosh Chilkoti
Elastin-like polypeptides as a purification tag for recombinant proteins.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2010;Chapter 6():Unit 6.11.
2010: Sarah R MacEwan; Daniel J Callahan; Ashutosh Chilkoti
Stimulus-responsive macromolecules and nanoparticles for cancer drug delivery.
Nanomedicine (London, England) 2010;5(5):793-806.
2010: Shahrul Alang Ahmad; Angus Hucknall; Ashutosh Chilkoti; Graham J Leggett
Protein patterning by UV-induced photodegradation of poly(oligo(ethylene glycol) methacrylate) brushes.
Langmuir : the ACS journal of surfaces and colloids 2010;26(12):9937-42.
2010: Nathan J Jenness; Ryan T Hill; Angus Hucknall; Ashutosh Chilkoti; Robert L Clark
A versatile diffractive maskless lithography for single-shot and serial microfabrication.
Optics express 2010;18(11):11754-62.
2010: Wenge Liu; J Andrew MacKay; Matthew R Dreher; Mingnan Chen; Jonathan R McDaniel; Andrew J Simnick; Daniel J Callahan; Michael R Zalutsky; Ashutosh Chilkoti
Injectable intratumoral depot of thermally responsive polypeptide-radionuclide conjugates delays tumor progression in a mouse model.
Journal of controlled release : official journal of the Controlled Release Society 2010;144(1):2-9.
2010: Andrew J Simnick; C Alexander Valencia; Rihe Liu; Ashutosh Chilkoti
Morphing low-affinity ligands into high-avidity nanoparticles by thermally triggered self-assembly of a genetically encoded polymer.
ACS nano 2010;4(4):2217-27.
2010: Jonathan R McDaniel; John Andrew Mackay; Felipe García Quiroz; Ashutosh Chilkoti
Recursive directional ligation by plasmid reconstruction allows rapid and seamless cloning of oligomeric genes.
Biomacromolecules 2010;11(4):944-52.
2010: Sarah R MacEwan; Ashutosh Chilkoti
Elastin-like polypeptides: biomedical applications of tunable biopolymers.
Biopolymers 2010;94(1):60-77.
2010: Dana L Nettles; Mansoor A Haider; Ashutosh Chilkoti; Lori A Setton
Neural network analysis identifies scaffold properties necessary for in vitro chondrogenesis in elastin-like polypeptide biopolymer scaffolds.
Tissue engineering. Part A 2010;16(1):11-20.
2009: J Andrew MacKay; Mingnan Chen; Jonathan R McDaniel; Wenge Liu; Andrew J Simnick; Ashutosh Chilkoti
Self-assembling chimeric polypeptide-doxorubicin conjugate nanoparticles that abolish tumours after a single injection.
Nature materials 2009;8(12):993-9.
2009: Younhee Cho; Laura B Sagle; Satoshi Iimura; Yanjie Zhang; Jaibir Kherb; Ashutosh Chilkoti; J Martin Scholtz; Paul S Cremer
Hydrogen bonding of beta-turn structure is stabilized in D(2)O.
Journal of the American Chemical Society 2009;131(42):15188-93.
2009: W Gao; Wenge Liu; John Andrew Mackay; Michael R Zalutsky; Eric J Toone; Ashutosh Chilkoti
In situ growth of a stoichiometric PEG-like conjugate at a protein's N-terminus with significantly improved pharmacokinetics.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(36):15231-6.
2009: Dana L Nettles; Ashutosh Chilkoti; Lori A Setton
Early metabolite levels predict long-term matrix accumulation for chondrocytes in elastin-like polypeptide biopolymer scaffolds.
Tissue engineering. Part A 2009;15(8):2113-21.
2009: Trine Christensen; Miriam Amiram; Sue Dagher; Kimberly Trabbic-Carlson; Mohammed F Shamji; Lori A Setton; Ashutosh Chilkoti
Fusion order controls expression level and activity of elastin-like polypeptide fusion proteins.
Protein science : a publication of the Protein Society 2009;18(7):1377-87.
2009: Greg J Nusz; Adam C Curry; Stella M Marinakos; Adam Wax; Ashutosh Chilkoti
Rational selection of gold nanorod geometry for label-free plasmonic biosensors.
ACS nano 2009;3(4):795-806.
2009: Yiquan Wu; John Andrew Mackay; Jonathan R McDaniel; Ashutosh Chilkoti; Robert L Clark
Fabrication of elastin-like polypeptide nanoparticles for drug delivery by electrospraying.
Biomacromolecules 2009;10(1):19-24.
2008: Bumjoon Kim; Ashutosh Chilkoti
Allosteric actuation of inverse phase transition of a stimulus-responsive fusion polypeptide by ligand binding.
Journal of the American Chemical Society 2008;130(52):17867-73.
2008: Younhee Cho; Yanjie Zhang; Trine Christensen; Laura B Sagle; Ashutosh Chilkoti; Paul S Cremer
Effects of Hofmeister anions on the phase transition temperature of elastin-like polypeptides.
The journal of physical chemistry. B 2008;112(44):13765-71.
2008: John Andrew Mackay; Ashutosh Chilkoti
Temperature sensitive peptides: engineering hyperthermia-directed therapeutics.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2008;24(6):483-95.
2008: Alexei Valiaev; Dong Woo Lim; Scott Schmidler; Robert L Clark; Ashutosh Chilkoti; Stefan Zauscher
Hydration and conformational mechanics of single, end-tethered elastin-like polypeptides.
Journal of the American Chemical Society 2008;130(33):10939-46.
2008: Mohammed F Shamji; Jun Chen; Allan H Friedman; William J Richardson; Ashutosh Chilkoti; Lori A Setton
Synthesis and characterization of a thermally-responsive tumor necrosis factor antagonist.
Journal of controlled release : official journal of the Controlled Release Society 2008;129(3):179-86.
2008: JJ Mock; Ryan T Hill; Aloyse Degiron; Stefan Zauscher; Ashutosh Chilkoti; David R Smith
Distance-dependent plasmon resonant coupling between a gold nanoparticle and gold film.
Nano letters 2008;8(8):2245-52.
2008: Dana L Nettles; Kenichi Kitaoka; Neil A Hanson; Charlene M Flahiff; Brian A Mata; Edward W Hsu; Ashutosh Chilkoti; Lori A Setton
In situ crosslinking elastin-like polypeptide gels for application to articular cartilage repair in a goat osteochondral defect model.
Tissue engineering. Part A 2008;14(7):1133-40.
2008: Mohammed F Shamji; Lyman Whitlatch; Allan H Friedman; William J Richardson; Ashutosh Chilkoti; Lori A Setton
An injectable and in situ-gelling biopolymer for sustained drug release following perineural administration.
Spine 2008;33(7):748-54.
2008: Greg J Nusz; Stella M Marinakos; Adam C Curry; Andreas B Dahlin; Fredrik Höök; Adam Wax; Ashutosh Chilkoti
Label-free plasmonic detection of biomolecular binding by a single gold nanorod.
Analytical chemistry 2008;80(4):984-9.
2008: Matthew R Dreher; Andrew J Simnick; Karl Fischer; Richard J Smith; Anand Patel; Manfred Schmidt; Ashutosh Chilkoti
Temperature triggered self-assembly of polypeptides into multivalent spherical micelles.
Journal of the American Chemical Society 2008;130(2):687-94.
2008: Dong Woo Lim; Dana L Nettles; Lori A Setton; Ashutosh Chilkoti
In situ cross-linking of elastin-like polypeptide block copolymers for tissue repair.
Biomacromolecules 2008;9(1):222-30.
2007: Dominic C Chow; Ashutosh Chilkoti
Surface-initiated enzymatic polymerization of DNA.
Langmuir : the ACS journal of surfaces and colloids 2007;23(23):11712-7.
2007: Mohammed F Shamji; Helawe Betre; Virginia B Kraus; Jun Chen; Ashutosh Chilkoti; Rajeswari Pichika; Koichi Masuda; Lori A Setton
Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1 receptor antagonist: sustained release of a local antiinflammatory therapeutic.
Arthritis and rheumatism 2007;56(11):3650-61.
2007: S Kenny Roberts; Ashutosh Chilkoti; Lori A Setton
Multifunctional thermally transitioning oligopeptides prepared by ring-opening metathesis polymerization.
Biomacromolecules 2007;8(8):2618-21.
2007: Dong-Hwan Kim; Jason Smith; Ashutosh Chilkoti; William M Reichert
The effect of covalently immobilized rhIL-1ra-ELP fusion protein on the inflammatory profile of LPS-stimulated human monocytes.
Biomaterials 2007;28(23):3369-77.
2007: Stella M Marinakos; Sihai Chen; Ashutosh Chilkoti
Plasmonic detection of a model analyte in serum by a gold nanorod sensor.
Analytical chemistry 2007;79(14):5278-83.
2007: Matthew R Dreher; Ashutosh Chilkoti
Toward a systems engineering approach to cancer drug delivery.
Journal of the National Cancer Institute 2007;99(13):983-5.
2007: Alexei Valiaev; Dong Woo Lim; Terrence G Oas; Ashutosh Chilkoti; Stefan Zauscher
Force-induced prolyl cis-trans isomerization in elastin-like polypeptides.
Journal of the American Chemical Society 2007;129(20):6491-7.
2007: Matthew R Dreher; Wenge Liu; Charles R Michelich; Mark Dewhirst; Ashutosh Chilkoti
Thermal cycling enhances the accumulation of a temperature-sensitive biopolymer in solid tumors.
Cancer research 2007;67(9):4418-24.
2007: Dong Woo Lim; Dana L Nettles; Lori A Setton; Ashutosh Chilkoti
Rapid cross-linking of elastin-like polypeptides with (hydroxymethyl)phosphines in aqueous solution.
Biomacromolecules 2007;8(5):1463-70.
2007: Dong Woo Lim; Kimberly Trabbic-Carlson; John Andrew Mackay; Ashutosh Chilkoti
Improved non-chromatographic purification of a recombinant protein by cationic elastin-like polypeptides.
Biomacromolecules 2007;8(5):1417-24.
2007: Adam Curry; Gregory Nusz; Ashutosh Chilkoti; Adam Wax
Analysis of total uncertainty in spectral peak measurements for plasmonic nanoparticle-based biosensors.
Applied optics 2007;46(10):1931-9.
2007: Woo-Kyung Lee; Sihai Chen; Ashutosh Chilkoti; Stefan Zauscher
Fabrication of gold nanowires by electric-field-induced scanning probe lithography and in situ chemical development.
Small (Weinheim an der Bergstrasse, Germany) 2007;3(2):249-54.
2007: Alexei Valiaev; Nehal I Abu-Lail; Dong Woo Lim; Ashutosh Chilkoti; Stefan Zauscher
Microcantilever sensing and actuation with end-grafted stimulus-responsive elastin-like polypeptides.
Langmuir : the ACS journal of surfaces and colloids 2007;23(1):339-44.
2007: Trine Christensen; Kimberly Trabbic-Carlson; Wenge Liu; Ashutosh Chilkoti
Purification of recombinant proteins from Escherichia coli at low expression levels by inverse transition cycling.
Analytical biochemistry 2007;360(1):166-8.
2006: Ashutosh Chilkoti; Trine Christensen; John Andrew Mackay
Stimulus responsive elastin biopolymers: Applications in medicine and biotechnology.
Current opinion in chemical biology 2006;10(6):652-7.
2006: Wenge Liu; Matthew R Dreher; Darin Yale Furgeson; Katia V Peixoto; Hong Yuan; Michael R Zalutsky; Ashutosh Chilkoti
Tumor accumulation, degradation and pharmacokinetics of elastin-like polypeptides in nude mice.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):170-8.
2006: Xin Ge; Kimberly Trabbic-Carlson; Ashutosh Chilkoti; Carlos D M Filipe
Purification of an elastin-like fusion protein by microfiltration.
Biotechnology and bioengineering 2006;95(3):424-32.
2006: Helawe Betre; Wenge Liu; Michael R Zalutsky; Ashutosh Chilkoti; Virginia B Kraus; Lori A Setton
A thermally responsive biopolymer for intra-articular drug delivery.
Journal of controlled release : official journal of the Controlled Release Society 2006;115(2):175-82.
2006: Wenge Liu; Matthew R Dreher; Dominic C Chow; Michael R Zalutsky; Ashutosh Chilkoti
Tracking the in vivo fate of recombinant polypeptides by isotopic labeling.
Journal of controlled release : official journal of the Controlled Release Society 2006;114(2):184-92.
2006: Yanjie Zhang; Kimberly Trabbic-Carlson; Fernando Albertorio; Ashutosh Chilkoti; Paul S Cremer
Aqueous two-phase system formation kinetics for elastin-like polypeptides of varying chain length.
Biomacromolecules 2006;7(7):2192-9.
2006: John W Pyhtila; Hongwei Ma; Andrew J Simnick; Ashutosh Chilkoti; Adam Wax
Analysis of long range correlations due to coherent light scattering from in-vitro cell arrays using angle-resolved low coherence interferometry.
Journal of biomedical optics 2006;11(3):34022.
2006: Dominic C Chow; Matthew R Dreher; Kimberly Trabbic-Carlson; Ashutosh Chilkoti
Ultra-high expression of a thermally responsive recombinant fusion protein in E. coli.
Biotechnology progress 2006;22(3):638-46.
2006: Hongwei Ma; Dejin Li; Xia Sheng; Bin Zhao; Ashutosh Chilkoti
Protein-resistant polymer coatings on silicon oxide by surface-initiated atom transfer radical polymerization.
Langmuir : the ACS journal of surfaces and colloids 2006;22(8):3751-6.
2006: Matthew R Dreher; Wenge Liu; Charles R Michelich; Mark Dewhirst; Fan Yuan; Ashutosh Chilkoti
Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers.
Journal of the National Cancer Institute 2006;98(5):335-44.
2006: Shin R Ong; Kimberly Trabbic-Carlson; Dana L Nettles; Dong Woo Lim; Ashutosh Chilkoti; Lori A Setton
Epitope tagging for tracking elastin-like polypeptides.
Biomaterials 2006;27(9):1930-5.
2006: Jinho Hyun; Jun Chen; Lori A Setton; Ashutosh Chilkoti
Patterning cells in highly deformable microstructures: effect of plastic deformation of substrate on cellular phenotype and gene expression.
Biomaterials 2006;27(8):1444-51.
2006: Darin Yale Furgeson; Matthew R Dreher; Ashutosh Chilkoti
Structural optimization of a "smart" doxorubicin-polypeptide conjugate for thermally targeted delivery to solid tumors.
Journal of controlled release : official journal of the Controlled Release Society 2006;110(2):362-9.
2006: Helawe Betre; Shin R Ong; Farshid Guilak; Ashutosh Chilkoti; Beverley Fermor; Lori A Setton
Chondrocytic differentiation of human adipose-derived adult stem cells in elastin-like polypeptide.
Biomaterials 2006;27(1):91-9.
2005: Melissa K McHale; Lori A Setton; Ashutosh Chilkoti
Synthesis and in vitro evaluation of enzymatically cross-linked elastin-like polypeptide gels for cartilaginous tissue repair.
Tissue engineering 2005;11(11-12):1768-79.
2005: Zhanping Zhang; Hongwei Ma; Douglas B Hausner; Ashutosh Chilkoti; Thomas P Beebe
Pretreatment of amphiphilic comb polymer surfaces dramatically affects protein adsorption.
Biomacromolecules 2005;6(6):3388-96.
2005: Dominic C Chow; Woo-Kyung Lee; Stefan Zauscher; Ashutosh Chilkoti
Enzymatic fabrication of DNA nanostructures: extension of a self-assembled oligonucleotide monolayer on gold arrays.
Journal of the American Chemical Society 2005;127(41):14122-3.
2005: Xin Ge; Daniel S C Yang; Kimberly Trabbic-Carlson; Bumjoon Kim; Ashutosh Chilkoti; Carlos D M Filipe
Self-cleavable stimulus responsive tags for protein purification without chromatography.
Journal of the American Chemical Society 2005;127(32):11228-9.
2004: Kimberly Trabbic-Carlson; Li Liu; Bumjoon Kim; Ashutosh Chilkoti
Expression and purification of recombinant proteins from Escherichia coli: Comparison of an elastin-like polypeptide fusion with an oligohistidine fusion.
Protein science : a publication of the Protein Society 2004;13(12):3274-84.
2004: Matthew R Dreher; Martyna Elas; Kazuhiro Ichikawa; Eugene D Barth; Ashutosh Chilkoti; Gerald M. Rosen; Howard J Halpern; Mark Dewhirst
Nitroxide conjugate of a thermally responsive elastin-like polypeptide for noninvasive thermometry.
Medical physics 2004;31(10):2755-62.
2004: Nidhi Nath; Ashutosh Chilkoti
Label-free biosensing by surface plasmon resonance of nanoparticles on glass: optimization of nanoparticle size.
Analytical chemistry 2004;76(18):5370-8.
2004: Nidhi Nath; Ashutosh Chilkoti
Label free colorimetric biosensing using nanoparticles.
Journal of fluorescence 2004;14(4):377-89.
2004: Jinho Hyun; Woo-Kyung Lee; Nidhi Nath; Ashutosh Chilkoti; Stefan Zauscher
Capture and release of proteins on the nanoscale by stimuli-responsive elastin-like polypeptide "switches".
Journal of the American Chemical Society 2004;126(23):7330-5.
2004: Dan E Meyer; Ashutosh Chilkoti
Quantification of the effects of chain length and concentration on the thermal behavior of elastin-like polypeptides.
Biomacromolecules 2004;5(3):846-51.
2004: Jinho Hyun; Jeonghan Kim; Stephen L Craig; Ashutosh Chilkoti
Enzymatic nanolithography of a self-assembled oligonucleotide monolayer on gold.
Journal of the American Chemical Society 2004;126(15):4770-1.
2004: Kimberly Trabbic-Carlson; Dan E Meyer; L Liu; Ronald T Piervincenzi; Nidhi Nath; Thomas H LaBean; Ashutosh Chilkoti
Effect of protein fusion on the transition temperature of an environmentally responsive elastin-like polypeptide: a role for surface hydrophobicity?
Protein engineering, design & selection : PEDS 2004;17(1):57-66.
2004: Ronald T Piervincenzi; Ashutosh Chilkoti
Effect of genetic circular permutation near the active site on the activity and stability of an enzyme inhibitor.
Biomolecular engineering 2004;21(1):33-42.
2003: Matthew R Dreher; Drazen Raucher; Narayanan Balu; O Michael Colvin; Susan M Ludeman; Ashutosh Chilkoti
Evaluation of an elastin-like polypeptide-doxorubicin conjugate for cancer therapy.
Journal of controlled release : official journal of the Controlled Release Society 2003;91(1-2):31-43.
2003: Kimberly Trabbic-Carlson; Lori A Setton; Ashutosh Chilkoti
Swelling and mechanical behaviors of chemically cross-linked hydrogels of elastin-like polypeptides.
Biomacromolecules 2003;4(3):572-80.
2003: Nidhi Nath; Ashutosh Chilkoti
Fabrication of a reversible protein array directly from cell lysate using a stimuli-responsive polypeptide.
Analytical chemistry 2003;75(4):709-15.
2003: Bernard P Chan; Ashutosh Chilkoti; William M Reichert; George A Truskey
Effect of streptavidin affinity mutants on the integrin-independent adhesion of biotinylated endothelial cells.
Biomaterials 2003;24(4):559-70.
2002: Ashutosh Chilkoti; Matthew R Dreher; Dan E Meyer
Design of thermally responsive, recombinant polypeptide carriers for targeted drug delivery.
Advanced drug delivery reviews 2002;54(8):1093-111.
2002: Ashutosh Chilkoti; Matthew R Dreher; Dan E Meyer; Drazen Raucher
Targeted drug delivery by thermally responsive polymers.
Advanced drug delivery reviews 2002;54(5):613-30.
2002: Helawe Betre; Lori A Setton; Dan E Meyer; Ashutosh Chilkoti
Characterization of a genetically engineered elastin-like polypeptide for cartilaginous tissue repair.
Biomacromolecules 2002;3(5):910-6.
2002: Dan E Meyer; Ashutosh Chilkoti
Genetically encoded synthesis of protein-based polymers with precisely specified molecular weight and sequence by recursive directional ligation: examples from the elastin-like polypeptide system.
Biomacromolecules 2002;3(2):357-67.
2002: Nidhi Nath; Ashutosh Chilkoti
A colorimetric gold nanoparticle sensor to interrogate biomolecular interactions in real time on a surface.
Analytical chemistry 2002;74(3):504-9.
2001: Drazen Raucher; Ashutosh Chilkoti
Enhanced uptake of a thermally responsive polypeptide by tumor cells in response to its hyperthermia-mediated phase transition.
Cancer research 2001;61(19):7163-70.
2001: Nidhi Nath; Ashutosh Chilkoti
Interfacial phase transition of an environmentally responsive elastin biopolymer adsorbed on functionalized gold nanoparticles studied by colloidal surface plasmon resonance.
Journal of the American Chemical Society 2001;123(34):8197-202.
2001: Jinho Hyun; Ashutosh Chilkoti
Micropatterning biological molecules on a polymer surface using elastomeric microwells.
Journal of the American Chemical Society 2001;123(28):6943-4.
2001: Dan E Meyer; B C Shin; GA Kong; Mark Dewhirst; Ashutosh Chilkoti
Drug targeting using thermally responsive polymers and local hyperthermia.
Journal of controlled release : official journal of the Controlled Release Society 2001;74(1-3):213-24.
2001: Dan E Meyer; Kimberly Trabbic-Carlson; Ashutosh Chilkoti
Protein purification by fusion with an environmentally responsive elastin-like polypeptide: effect of polypeptide length on the purification of thioredoxin.
Biotechnology progress 2001;17(4):720-8.
2001: Dan E Meyer; GA Kong; Mark Dewhirst; Michael R Zalutsky; Ashutosh Chilkoti
Targeting a genetically engineered elastin-like polypeptide to solid tumors by local hyperthermia.
Cancer research 2001;61(4):1548-54.
1999: Dan E Meyer; Ashutosh Chilkoti
Purification of recombinant proteins by fusion with thermally-responsive polypeptides.
Nature biotechnology 1999;17(11):1112-5.