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Floyd Chilton

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Gas Chromatography-Mass Spectrometry

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Co-Publications
Name
29
Fonteh, Alfred
14
Winkler, James
12
Surette, Marc
11
High, Kevin
9
Hubbard, Walter
9
Sung, Chiu-Mei
7
Clay, Carl
7
Atsumi, GI
7
Seeds, Michael
5
Marshall, Lisa
5
Edens, Michelle
4
Bass, David
4
Monjazeb, Arta
4
Namen, Andrew
4
Undem, Bradley

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Publications

TOP 3
Seeds Michael C; Peachman Kristina K; Bowton David L; Sivertson Kelly L; Chilton Floyd H
Regulation of arachidonate remodeling enzymes impacts eosinophil survival during allergic asthma.
Chilton Floyd H
Regarding favorable and unfavorable PUFA in fish.
Chilton Floyd H; Rudel Lawrence L; Parks John S; Arm Jonathan P; Seeds Michael C
Mechanisms by which botanical lipids affect inflammatory disorders.

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All Publications

2009: Seeds Michael C; Peachman Kristina K; Bowton David L; Sivertson Kelly L; Chilton Floyd H
Regulation of arachidonate remodeling enzymes impacts eosinophil survival during allergic asthma.
American journal of respiratory cell and molecular biology 2009;41(3):358-66.
2008: Chilton Floyd H
Regarding favorable and unfavorable PUFA in fish.
Journal of the American Dietetic Association 2008;108(10):1614, 1616; author reply 1616.
2008: Chilton Floyd H; Rudel Lawrence L; Parks John S; Arm Jonathan P; Seeds Michael C
Mechanisms by which botanical lipids affect inflammatory disorders.
The American journal of clinical nutrition 2008;87(2):498S-503S.
2006: Monjazeb Arta M; High Kevin P; Connoy Abbie; Hart Lori S; Koumenis Constantinos; Chilton Floyd H
Arachidonic acid-induced gene expression in colon cancer cells.
Carcinogenesis 2006;27(10):1950-60.
2005: Monjazeb Arta M; High Kevin P; Koumenis Constantinos; Chilton Floyd H
Inhibitors of arachidonic acid metabolism act synergistically to signal apoptosis in neoplastic cells.
Prostaglandins, leukotrienes, and essential fatty acids 2005;73(6):463-74.
2004: Surette Marc E; Edens Michelle; Chilton Floyd H; Tramposch Kenneth M
Dietary echium oil increases plasma and neutrophil long-chain (n-3) fatty acids and lowers serum triacylglycerols in hypertriglyceridemic humans.
The Journal of nutrition 2004;134(6):1406-11.
2003: Surette Marc E; Koumenis Iphigenia L; Edens Michelle B; Tramposch Kenneth M; Clayton Bert; Bowton David; Chilton Floyd H
Inhibition of leukotriene biosynthesis by a novel dietary fatty acid formulation in patients with atopic asthma: a randomized, placebo-controlled, parallel-group, prospective trial.
Clinical therapeutics 2003;25(3):972-9.
2003: Surette Marc E; Koumenis Iphigenia L; Edens Michelle B; Tramposch Kenneth M; Chilton Floyd H
Inhibition of leukotriene synthesis, pharmacokinetics, and tolerability of a novel dietary fatty acid formulation in healthy adult subjects.
Clinical therapeutics 2003;25(3):948-71.
2003: High K P; Sinclair J; Easter L H; Case D; Chilton F H
Advanced age, but not anergy, is associated with altered serum polyunsaturated fatty acid levels.
The journal of nutrition, health & aging 2003;7(6):378-84.
2002: Clay Carl E; Monjazeb Arta; Thorburn Jacqueline; Chilton Floyd H; High Kevin P
15-Deoxy-delta12,14-prostaglandin J2-induced apoptosis does not require PPARgamma in breast cancer cells.
Journal of lipid research 2002;43(11):1818-28.
2002: Monjazeb A M; Clay C E; High K P; Chilton F H
Antineoplastic properties of arachidonic acid and its metabolites.
Prostaglandins, leukotrienes, and essential fatty acids 2002;66(1):5-12.
2001: Clay C E; Atsumi G I; High K P; Chilton F H
Early de novo gene expression is required for 15-deoxy-Delta 12,14-prostaglandin J2-induced apoptosis in breast cancer cells.
The Journal of biological chemistry 2001;276(50):47131-5.
2001: Fonteh A N; Marion C R; Barham B J; Edens M B; Atsumi G; Samet J M; High K P; Chilton F H
Enhancement of mast cell survival: a novel function of some secretory phospholipase A(2) isotypes.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(8):4161-71.
2001: Clay C E; Namen A M; Atsumi G; Trimboli A J; Fonteh A N; High K P; Chilton F H
Magnitude of peroxisome proliferator-activated receptor-gamma activation is associated with important and seemingly opposite biological responses in breast cancer cells.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2001;49(5):413-20.
2000: Fonteh A N; Atsumi G; LaPorte T; Chilton F H
Secretory phospholipase A2 receptor-mediated activation of cytosolic phospholipase A2 in murine bone marrow-derived mast cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(5):2773-82.
2000: Barham J B; Edens M B; Fonteh A N; Johnson M M; Easter L; Chilton F H
Addition of eicosapentaenoic acid to gamma-linolenic acid-supplemented diets prevents serum arachidonic acid accumulation in humans.
The Journal of nutrition 2000;130(8):1925-31.
2000: Clay C E; Namen A M; Fonteh A N; Atsumi G; High K P; Chilton F H
15-deoxy-Delta(12,14)PGJ(2) induces diverse biological responses via PPARgamma activation in cancer cells.
Prostaglandins & other lipid mediators 2000;62(1):23-32.
1999: Trimboli A J; Waite B M; Atsumi G; Fonteh A N; Namen A M; Clay C E; Kute T E; High K P; Willingham M C; Chilton F H
Influence of coenzyme A-independent transacylase and cyclooxygenase inhibitors on the proliferation of breast cancer cells.
Cancer research 1999;59(24):6171-7.
1999: Clay C E; Namen A M; Atsumi G; Willingham M C; High K P; Kute T E; Trimboli A J; Fonteh A N; Dawson P A; Chilton F H
Influence of J series prostaglandins on apoptosis and tumorigenesis of breast cancer cells.
Carcinogenesis 1999;20(10):1905-11.
1999: Johnson M M; Vaughn B; Triggiani M; Swan D D; Fonteh A N; Chilton F H
Role of arachidonyl triglycerides within lipid bodies in eicosanoid formation by human polymorphonuclear cells.
American journal of respiratory cell and molecular biology 1999;21(2):253-8.
1999: Surette M E; Fonteh A N; Bernatchez C; Chilton F H
Perturbations in the control of cellular arachidonic acid levels block cell growth and induce apoptosis in HL-60 cells.
Carcinogenesis 1999;20(5):757-63.
1998: Fonteh A N; Samet J M; Surette M; Reed W; Chilton F H
Mechanisms that account for the selective release of arachidonic acid from intact cells by secretory phospholipase A2.
Biochimica et biophysica acta 1998;1393(2-3):253-66.
1998: Surette M E; Chilton F H
The distribution and metabolism of arachidonate-containing phospholipids in cellular nuclei.
The Biochemical journal 1998;330 ( Pt 2)():915-21.
1998: Seeds M C; Jones D F; Chilton F H; Bass D A
Secretory and cytosolic phospholipases A2 are activated during TNF priming of human neutrophils.
Biochimica et biophysica acta 1998;1389(3):273-84.
1997: Johnson M M; Swan D D; Surette M E; Stegner J; Chilton T; Fonteh A N; Chilton F H
Dietary supplementation with gamma-linolenic acid alters fatty acid content and eicosanoid production in healthy humans.
The Journal of nutrition 1997;127(8):1435-44.
1996: Winkler J D; Eris T; Sung C M; Chabot-Fletcher M; Mayer R J; Surette M E; Chilton F H
Inhibitors of coenzyme A-independent transacylase induce apoptosis in human HL-60 cells.
The Journal of pharmacology and experimental therapeutics 1996;279(2):956-66.
1996: Surette M E; Winkler J D; Fonteh A N; Chilton F H
Relationship between arachidonate--phospholipid remodeling and apoptosis.
Biochemistry 1996;35(28):9187-96.
1996: Samet J M; Fonteh A N; Galli S J; Tsai M; Fasano M B; Chilton F H
Alterations in arachidonic acid metabolism in mouse mast cells induced to undergo maturation in vitro in response to stem cell factor.
The Journal of allergy and clinical immunology 1996;97(6):1329-41.
1996: Chilton F H; Averill F J; Hubbard W C; Fonteh A N; Triggiani M; Liu M C
Antigen-induced generation of lyso-phospholipids in human airways.
The Journal of experimental medicine 1996;183(5):2235-45.
1996: Chilton-Lopez; Surette M E; Swan D D; Fonteh A N; Johnson M M; Chilton F H
Metabolism of gammalinolenic acid in human neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(8):2941-7.
1996: Chilton F H; Fonteh A N; Surette M E; Triggiani M; Winkler J D
Control of arachidonate levels within inflammatory cells.
Biochimica et biophysica acta 1996;1299(1):1-15.
1996: Chilton F H; Surette M E; Winkler J D
Arachidonate-phospholipid remodeling and cell proliferation.
Advances in experimental medicine and biology 1996;416():169-72.
1996: Winkler J D; Sung C M; Marshall L A; Chilton F H
Inhibitors of arachidonate metabolism and effects on PAF production.
Advances in experimental medicine and biology 1996;416():11-5.
1995: Triggiani M; Oriente A; Seeds M C; Bass D A; Marone G; Chilton F H
Migration of human inflammatory cells into the lung results in the remodeling of arachidonic acid into a triglyceride pool.
The Journal of experimental medicine 1995;182(5):1181-90.
1995: Winkler J D; Fonteh A N; Sung C M; Heravi J D; Nixon A B; Chabot-Fletcher M; Griswold D; Marshall L A; Chilton F H
Effects of CoA-independent transacylase inhibitors on the production of lipid inflammatory mediators.
The Journal of pharmacology and experimental therapeutics 1995;274(3):1338-47.
1995: Ely E W; Seeds M C; Chilton F H; Bass D A
Neutrophil release of arachidonic acid, oxidants, and proteinases: causally related or independent.
Biochimica et biophysica acta 1995;1258(2):135-44.
1995: Fonteh A N; Samet J M; Chilton F H
Regulation of arachidonic acid, eicosanoid, and phospholipase A2 levels in murine mast cells by recombinant stem cell factor.
The Journal of clinical investigation 1995;96(3):1432-9.
1995: Chilton F H; Fonteh A N; Sung C M; Hickey D M; Torphy T J; Mayer R J; Marshall L A; Heravi J D; Winkler J D
Inhibitors of CoA-independent transacylase block the movement of arachidonate into 1-ether-linked phospholipids of human neutrophils.
Biochemistry 1995;34(16):5403-10.
1995: Samet J M; Fasano M B; Fonteh A N; Chilton F H
Selective induction of prostaglandin G/H synthase I by stem cell factor and dexamethasone in mast cells.
The Journal of biological chemistry 1995;270(14):8044-9.
1995: Winkler J D; Fonteh A N; Sung C M; Huang L; Chabot-Fletcher M; Marshall L A; Chilton F H
Inhibition of CoA-independent transacylase reduces inflammatory lipid mediators.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():89-91.
1994: Winkler J D; Sung C M; Huang L; Chilton F H
CoA-independent transacylase activity is increased in human neutrophils after treatment with tumor necrosis factor alpha.
Biochimica et biophysica acta 1994;1215(1-2):133-40.
1994: Diez E; Chilton F H; Stroup G; Mayer R J; Winkler J D; Fonteh A N
Fatty acid and phospholipid selectivity of different phospholipase A2 enzymes studied by using a mammalian membrane as substrate.
The Biochemical journal 1994;301 ( Pt 3)():721-6.
1994: Stadel J M; Hoyle K; Naclerio R M; Roshak A; Chilton F H
Characterization of phospholipase A2 from human nasal lavage.
American journal of respiratory cell and molecular biology 1994;11(1):108-13.
1994: Fonteh A N; Bass D A; Marshall L A; Seeds M; Samet J M; Chilton F H
Evidence that secretory phospholipase A2 plays a role in arachidonic acid release and eicosanoid biosynthesis by mast cells.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(11):5438-46.
1994: Bass D A; Seeds M C; Jones D F; Chilton F H; Bauldry S A
Priming of phospholipases A2 of human neutrophils by tumor necrosis factor.
Chest 1994;105(3 Suppl):99S-100S.
1994: Shin M H; Averill F J; Hubbard W C; Chilton F H; Baroody F M; Liu M C; Naclerio R M
Nasal allergen challenge generates 1-0-hexadecyl-2-lyso-sn-glycero-3-phosphocholine.
American journal of respiratory and critical care medicine 1994;149(3 Pt 1):660-6.
1993: Columbo M; Horowitz E M; Patella V; Kagey-Sobotka A; Chilton F H; Lichtenstein L M
A comparative study of the effects of 1-acyl-2-acetyl-sn-glycero-3-phosphocholine and platelet activating factor on histamine and leukotriene C4 release from human leukocytes.
The Journal of allergy and clinical immunology 1993;92(2):325-33.
1993: Fonteh A N; Winkler J D; Torphy T J; Heravi J; Undem B J; Chilton F H
Influence of isoproterenol and phosphodiesterase inhibitors on platelet-activating factor biosynthesis in the human neutrophil.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(1):339-50.
1993: Winkler J D; Sung C M; Hubbard W C; Chilton F H
Influence of arachidonic acid on indices of phospholipase A2 activity in the human neutrophil.
The Biochemical journal 1993;291 ( Pt 3)():825-31.
1993: Fonteh A N; Chilton F H
Mobilization of different arachidonate pools and their roles in the generation of leukotrienes and free arachidonic acid during immunologic activation of mast cells.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(2):563-70.
1993: Chilton F H; Patel M; Fonteh A N; Hubbard W C; Triggiani M
Dietary n-3 fatty acid effects on neutrophil lipid composition and mediator production. Influence of duration and dosage.
The Journal of clinical investigation 1993;91(1):115-22.
1992: Triggiani M; Schleimer R P; Tomioka K; Hubbard W C; Chilton F H
Characterization of platelet-activating factor synthesized by normal and granulocyte-macrophage colony-stimulating factor-primed human eosinophils.
Immunology 1992;77(4):500-4.
1992: Winkler J D; Sung C M; Hubbard W C; Chilton F H
Evidence for different mechanisms involved in the formation of lyso platelet-activating factor and the calcium-dependent release of arachidonic acid from human neutrophils.
Biochemical pharmacology 1992;44(10):2055-66.
1992: Triggiani M; Chilton F H
Metabolism of platelet-activating factor in the guinea-pig heart.
Journal of molecular and cellular cardiology 1992;24(10):1101-11.
1992: Triggiani M; Fonteh A N; Chilton F H
Factors that influence the proportions of platelet-activating factor and 1-acyl-2-acetyl-sn-glycero-3-phosphocholine synthesized by the mast cell.
The Biochemical journal 1992;286 ( Pt 2)():497-503.
1992: O'Sullivan M G; Chilton F H; Huggins E M; McCall C E
Lipopolysaccharide priming of alveolar macrophages for enhanced synthesis of prostanoids involves induction of a novel prostaglandin H synthase.
The Journal of biological chemistry 1992;267(21):14547-50.
1992: Fonteh A N; Chilton F H
Rapid remodeling of arachidonate from phosphatidylcholine to phosphatidylethanolamine pools during mast cell activation.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(6):1784-91.
1992: Torphy T J; Livi G P; Balcarek J M; White J R; Chilton F H; Undem B J
Therapeutic potential of isozyme-selective phosphodiesterase inhibitors in the treatment of asthma.
Advances in second messenger and phosphoprotein research 1992;25():289-305.
1991: Nakamura T; Fonteh A N; Hubbard W C; Triggiani M; Inagaki N; Ishizaka T; Chilton F H
Arachidonic acid metabolism during antigen and ionophore activation of the mouse bone marrow derived mast cell.
Biochimica et biophysica acta 1991;1085(2):191-200.
1991: Churchill L; Chilton F H; Proud D
Interaction of platelet-activating factor with cultured guinea pig tracheal epithelial cells.
The Biochemical journal 1991;276 ( Pt 3)():593-8.
1991: Winkler J D; Sung C M; Bennett C F; Chilton F H
Characterization of CoA-independent transacylase activity in U937 cells.
Biochimica et biophysica acta 1991;1081(3):339-46.
1990: Triggiani M; Connell T R; Chilton F H
Evidence that increasing the cellular content of eicosapentaenoic acid does not reduce the biosynthesis of platelet-activating factor.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(7):2241-8.
1990: Triggiani M; Hubbard W C; Chilton F H
Synthesis of 1-acyl-2-acetyl-sn-glycero-3-phosphocholine by an enriched preparation of the human lung mast cell.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(12):4773-80.
1990: Undem B J; Torphy T J; Goldman D; Chilton F H
Inhibition by adenosine 3':5'-monophosphate of eicosanoid and platelet-activating factor biosynthesis in the mouse PT-18 mast cell.
The Journal of biological chemistry 1990;265(12):6750-8.
1990: Chilton F H; Lichtenstein L M
Lipid mediators of the allergic reaction.
Chemical immunology 1990;49():173-205.
1989: Cluzel M; Undem B J; Chilton F H
Release of platelet-activating factor and the metabolism of leukotriene B4 by the human neutrophil when studied in a cell superfusion model.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(11):3659-65.
1989: Triggiani M; Chilton F H
Influence of immunologic activation and cellular fatty acid levels on the catabolism of platelet-activating factor within the murine mast cell (PT-18).
Biochimica et biophysica acta 1989;1006(1):41-51.
1989: Churchill L; Chilton F H; Resau J H; Bascom R; Hubbard W C; Proud D
Cyclooxygenase metabolism of endogenous arachidonic acid by cultured human tracheal epithelial cells.
The American review of respiratory disease 1989;140(2):449-59.
1989: Chilton F H; Westcott J Y; Zapp L M; Henson J E; Voelkel N F
Incorporation of arachidonic acid into lipids of the isolated perfused rat lung.
Journal of applied physiology (Bethesda, Md. : 1985) 1989;66(6):2763-71.
1989: Chilton F H
Potential phospholipid source(s) of arachidonate used for the synthesis of leukotrienes by the human neutrophil.
The Biochemical journal 1989;258(2):327-33.
1988: Chilton F H; Connell T R
1-ether-linked phosphoglycerides. Major endogenous sources of arachidonate in the human neutrophil.
The Journal of biological chemistry 1988;263(11):5260-5.
1983: Walsh C E; Dechatelet L R; Chilton F H; Wykle R L; Waite M
Mechanism of arachidonic acid release in human polymorphonuclear leukocytes.
Biochimica et biophysica acta 1983;750(1):32-40.
1982: Chilton F H; O'Flaherty J T; Walsh C E; Thomas M J; Wykle R L; DeChatelet L R; Waite B M
Platelet activating factor. Stimulation of the lipoxygenase pathway in polymorphonuclear leukocytes by 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine.
The Journal of biological chemistry 1982;257(10):5402-7.

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