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Stephen Chim

Research Profile

Physiology

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Chemicals & Drugs

Genes & Molecular Sequences

Genome, Viral

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Protein Array Analysis

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Hong Kong

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Publications

TOP 3
Terence C W Poon; Joseph J Y Sung; Yu-Kwan Tong; Sai M Ngai; Ronald T K Pang; K C Allen Chan; Stephen S C Chim; Rossa W K Chiu; Nelson L S Lee; Y M Dennis Lo
Proteomic analysis reveals platelet factor 4 and beta-thromboglobulin as prognostic markers in severe acute respiratory syndrome.
Stephen S C Chim; Shara W Y Lee; Wing S Lee; Oi K Chan; Yuen H Ting; Tak Y Leung
Systematic identification of spontaneous preterm birth-associated RNA transcripts in maternal plasma.
Raymond R Y Wong; Y F Wong; So-Fan Yim; M Y Yu; Loucia K Y Chan; Tak-Hong Cheung; Stephen S C Chim; Coral W S Lee; Sophia N C Lee; Nelson S S Siu; Teresa P T Tsang; Tony K H Chung
CHD5 Downregulation Associated with Poor Prognosis in Epithelial Ovarian Cancer.

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All Publications

2012: Terence C W Poon; Joseph J Y Sung; Yu-Kwan Tong; Sai M Ngai; Ronald T K Pang; K C Allen Chan; Stephen S C Chim; Rossa W K Chiu; Nelson L S Lee; Y M Dennis Lo
Proteomic analysis reveals platelet factor 4 and beta-thromboglobulin as prognostic markers in severe acute respiratory syndrome.
Electrophoresis 2012;33(12):1894-900.
2012: Stephen S C Chim; Shara W Y Lee; Wing S Lee; Oi K Chan; Yuen H Ting; Tak Y Leung
Systematic identification of spontaneous preterm birth-associated RNA transcripts in maternal plasma.
PloS one 2012;7(4):e34328.
2011: Raymond R Y Wong; Y F Wong; So-Fan Yim; M Y Yu; Loucia K Y Chan; Tak-Hong Cheung; Stephen S C Chim; Coral W S Lee; Sophia N C Lee; Nelson S S Siu; Teresa P T Tsang; Tony K H Chung
CHD5 Downregulation Associated with Poor Prognosis in Epithelial Ovarian Cancer.
Gynecologic and obstetric investigation 2011;72(3):203-7.
2009: Emily C W Hung; Tristan K F Shing; Stephen S C Chim; Philip C Yeung; Rebecca Wing-Yan Chan; Ki-Wai Chik; Vincent Lee; Nancy B Y Tsui; Chi kong Li; Cesar S C Wong; Rossa W K Chiu; Y M Dennis Lo
Presence of donor-derived DNA and cells in the urine of sex-mismatched hematopoietic stem cell transplant recipients: implication for the transrenal hypothesis.
Clinical chemistry 2009;55(4):715-22.
2009: Sai Wang Seto; Ho Yeung Lam; Wing Sze Lau; Alice Lai Shan Au; Tze Yan Lam; Stephen S C Chim; Sai Ming Ngai; Shun-Wan Chan; Tak Yeung Leung; WANG XIN; Siu-Kai Kong; George P H Leung; Simon Ming Yuen Lee; Yiu Wa Kwan
Role of monoamine oxidases in the exaggerated 5-hydroxytryptamine-induced tension development of human isolated preeclamptic umbilical artery.
European journal of pharmacology 2009;605(1-3):129-37.
2008: Stephen S C Chim; Tristan K F Shing; Emily C W Hung; Tak Yeung Leung; tze lau; Rossa W K Chiu; Y M Dennis Lo
Detection and characterization of placental microRNAs in maternal plasma.
Clinical chemistry 2008;54(3):482-90.
2008: Stephen S C Chim; Shengnan Jin; Tracy Y H Lee; Fiona M F Lun; Wing S Lee; Lisa Y S Chan; Yongjie Jin; Ningning Yang; Yu K Tong; Tak Y Leung; tze lau; Chunming Ding; Rossa W K Chiu; Y M Dennis Lo
Systematic search for placental DNA-methylation markers on chromosome 21: toward a maternal plasma-based epigenetic test for fetal trisomy 21.
Clinical chemistry 2008;54(3):500-11.
2007: Dana W Y Tsui; Allen Chan; Stephen S C Chim; Lin Wai Chan; Tak Yeung Leung; tze lau; Y M Dennis Lo; Rossa W K Chiu
Quantitative aberrations of hypermethylated RASSF1A gene sequences in maternal plasma in pre-eclampsia.
Prenatal diagnosis 2007;27(13):1212-8.
2007: Sai Wang Seto; Alice Lai Shan Au; Tze Yan Lam; Stephen S C Chim; Simon Ming Yuen Lee; S Wan; D C S Tjiu; N Shigemura; A P C Yim; Shun-Wan Chan; Stephen Kwok-Wing Tsui; George P H Leung; Yiu Wa Kwan
Modulation by simvastatin of iberiotoxin-sensitive, Ca2+-activated K+ channels of porcine coronary artery smooth muscle cells.
British journal of pharmacology 2007;151(7):987-97.
2007: Rossa W K Chiu; Stephen S C Chim; Ivy H N Wong; Cesar S C Wong; Wing-Shan Lee; Ka-Fai To; Joanna H M Tong; Ryan Yuen; Alisa S W Shum; John K C Chan; Lisa Y S Chan; Jessie W F Yuen; Yu K Tong; Jingly F Weier; Christy Ferlatte; Tse N Leung; tze lau; Kwok-Wai Lo; Y M Dennis Lo
Hypermethylation of RASSF1A in human and rhesus placentas.
The American journal of pathology 2007;170(3):941-50.
2006: Allen Chan; Chunming Ding; Ageliki Gerovassili; Sze W Yeung; Rossa W K Chiu; Tse N Leung; tze lau; Stephen S C Chim; Grace T Y Chung; Kypros H Nicolaides; Y M Dennis Lo
Hypermethylated RASSF1A in maternal plasma: A universal fetal DNA marker that improves the reliability of noninvasive prenatal diagnosis.
Clinical chemistry 2006;52(12):2211-8.
2006: Yu K Tong; Chunming Ding; Rossa W K Chiu; Ageliki Gerovassili; Stephen S C Chim; Tak Y Leung; Tse N Leung; tze lau; Kypros H Nicolaides; Y M Dennis Lo
Noninvasive prenatal detection of fetal trisomy 18 by epigenetic allelic ratio analysis in maternal plasma: Theoretical and empirical considerations.
Clinical chemistry 2006;52(12):2194-202.
2006: Pang Ronald; Terence C W Poon; Allen Chan; Nelson L S Lee; Rossa W K Chiu; Yu K Tong; Stephen S C Chim; Joseph J Y Sung; Y M Dennis Lo
Serum amyloid A is not useful in the diagnosis of severe acute respiratory syndrome.
Clinical chemistry 2006;52(6):1202-4.
2006: Ka-Wing Au; Cecy Y C Kou; Anthony Woo; Stephen S C Chim; Kwok-Pui Fung; Christopher H K Cheng; Mary Waye; Stephen Kwok-Wing Tsui
Calcyclin binding protein promotes DNA synthesis and differentiation in rat neonatal cardiomyocytes.
Journal of cellular biochemistry 2006;98(3):555-66.
2006: Pang Ronald; Terence C W Poon; Allen Chan; Nelson L S Lee; Rossa W K Chiu; Yu K Tong; Ronald M Y Wong; Stephen S C Chim; Sai Ming Ngai; Joseph J Y Sung; Y M Dennis Lo
Serum proteomic fingerprints of adult patients with severe acute respiratory syndrome.
Clinical chemistry 2006;52(3):421-9.
2006: Stephen S C Chim; Rossa W K Chiu; Y M Dennis Lo
Genomic sequencing of the severe acute respiratory syndrome-coronavirus.
Methods in molecular biology (Clifton, N.J.) 2006;336():177-94.
2005: Stephen S C Chim; Yu K Tong; Rossa W K Chiu; tze lau; Tse N Leung; Lisa Y S Chan; Cees B M Oudejans; Chunming Ding; Y M Dennis Lo
Detection of the placental epigenetic signature of the maspin gene in maternal plasma.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(41):14753-8.
2005: Grace T Y Chung; Rossa W K Chiu; Jo L K Cheung; Yongjie Jin; Stephen S C Chim; Paul K S Chan; Y M Dennis Lo
A simple and rapid approach for screening of SARS-coronavirus genotypes: an evaluation study.
BMC infectious diseases 2005;5():87.
2005: Allen Chan; Nelson Tang; David S C Hui; Grace T Y Chung; A K L Wu; Stephen S C Chim; Rossa W K Chiu; Nelson Lee; Kin Wing CHOI; Ying-Man Sung; Paul K S Chan; Yu K Tong; Sik-To Lai; Wai-Cho Yu; Owen T Y Tsang; Y M Dennis Lo
Absence of association between angiotensin converting enzyme polymorphism and development of adult respiratory distress syndrome in patients with severe acute respiratory syndrome: a case control study.
BMC infectious diseases 2005;5():26.
2005: Rossa W K Chiu; Stephen S C Chim; Yu K Tong; Kitty S C Fung; Paul K S Chan; Guo-ping Zhao; Y M Dennis Lo
Tracing SARS-coronavirus variant with large genomic deletion.
Emerging infectious diseases 2005;11(1):168-70.
2004: Rossa W K Chiu; Nelson Tang; David S C Hui; Grace T Y Chung; Stephen S C Chim; Allen Chan; Ying-Man Sung; Louis Y S Chan; Yu K Tong; Wing-shan Lee; Paul K S Chan; Y M Dennis Lo
ACE2 gene polymorphisms do not affect outcome of severe acute respiratory syndrome.
Clinical chemistry 2004;50(9):1683-6.
2004: N B Y Tsui; Stephen S C Chim; Rossa W K Chiu; tze lau; Enders K.O. Ng; T N Leung; Yu K Tong; Allen Chan; Y M Dennis Lo
Systematic micro-array based identification of placental mRNA in maternal plasma: towards non-invasive prenatal gene expression profiling.
Journal of medical genetics 2004;41(6):461-7.
2004: Stephen S C Chim; Y M Dennis Lo
Molecular epidemiology of the coronavirus associated with severe acute respiratory syndrome: a review of data from the Chinese University of Hong Kong.
The Clinical biochemist. Reviews / Australian Association of Clinical Biochemists 2004;25(2):143-7.
2004: Ka-Fai To; Joanna H M Tong; Paul K S Chan; Florence W L Au; Stephen S C Chim; Allen Chan; Jo L K Cheung; Esther Y M Liu; Gary M K Tse; Anthony W I Lo; Y M Dennis Lo; Ho-Keung Ng
Tissue and cellular tropism of the coronavirus associated with severe acute respiratory syndrome: an in-situ hybridization study of fatal cases.
The Journal of pathology 2004;202(2):157-63.
2004: Stephen S C Chim; Yu K Tong; Emily C W Hung; Rossa W K Chiu; Y M Dennis Lo
Genomic sequencing of a SARS coronavirus isolate that predated the Metropole Hotel case cluster in Hong Kong.
Clinical chemistry 2004;50(1):231-3.
2003: Emily C W Hung; Stephen S C Chim; Paul K S Chan; Yu K Tong; Enders K.O. Ng; Rossa W K Chiu; Chi-Bon Leung; Joseph J Y Sung; John S Tam; Y M Dennis Lo
Detection of SARS coronavirus RNA in the cerebrospinal fluid of a patient with severe acute respiratory syndrome.
Clinical chemistry 2003;49(12):2108-9.
2003: Enders K.O. Ng; David S C Hui; Allen Chan; Emily C W Hung; Rossa W K Chiu; Nelson Lee; Alan Wu; Stephen S C Chim; Yu K Tong; Joseph J Y Sung; John S Tam; Y M Dennis Lo
Quantitative analysis and prognostic implication of SARS coronavirus RNA in the plasma and serum of patients with severe acute respiratory syndrome.
Clinical chemistry 2003;49(12):1976-80.
2003: Stephen S C Chim; Stephen Kwok-Wing Tsui; Allen Chan; Thomas C C Au; Emily C W Hung; Yu K Tong; Rossa W K Chiu; Enders K.O. Ng; Paul K S Chan; C M Chu; J J Y Sung; John S Tam; Kwok-Pui Fung; Mary Waye; C Y Lee; K Y Yuen; Y M Dennis Lo
Genomic characterisation of the severe acute respiratory syndrome coronavirus of Amoy Gardens outbreak in Hong Kong.
Lancet 2003;362(9398):1807-8.
2003: Rossa W K Chiu; Stephen S C Chim; Y M Dennis Lo
Molecular epidemiology of SARS--from Amoy Gardens to Taiwan.
The New England journal of medicine 2003;349(19):1875-6.
2003: Stephen Kwok-Wing Tsui; Stephen S C Chim; Y M Dennis Lo
Coronavirus genomic-sequence variations and the epidemiology of the severe acute respiratory syndrome.
The New England journal of medicine 2003;349(2):187-8.
2001: A H Chan; Simon Ming Yuen Lee; Stephen S C Chim; LD Kok; Mary Waye; Cheuk Yu Lee; Kwok-Pui Fung; Stephen Kwok-Wing Tsui
Molecular cloning and characterization of a RING-H2 finger protein, ANAPC11, the human homolog of yeast Apc11p.
Journal of cellular biochemistry 2001;83(2):249-58.
2000: Stephen S C Chim; S S Cheung; Stephen Kwok-Wing Tsui
Differential gene expression of rat neonatal heart analyzed by suppression subtractive hybridization and expressed sequence tag sequencing.
Journal of cellular biochemistry 2000;80(1):24-36.
2000: Stephen S C Chim; K Fung; Mary Waye; C Lee; Stephen Kwok-Wing Tsui
Expression of replication factor C 40-kDa subunit is down-regulated during neonatal development in rat ventricular myocardium.
Journal of cellular biochemistry 2000;78(4):533-40.
1999: Simon Ming Yuen Lee; H Y Li; Enders K.O. Ng; S M Or; Kwok Keung Chan; Masayo Kotaka; Stephen S C Chim; Stephen Kwok-Wing Tsui; Mary Waye; Kwok-Pui Fung; Cheuk Yu Lee
Characterization of a brain-specific nuclear LIM domain protein (FHL1B) which is an alternatively spliced variant of FHL1.
Gene 1999;237(1):253-63.
1998: Simon Ming Yuen Lee; Stephen Kwok-Wing Tsui; Kwok Keung Chan; Masayo Kotaka; H Y Li; Stephen S C Chim; Mary Waye; Kwok-Pui Fung; Cheuk Yu Lee
Chromosomal mapping of a skeletal muscle specific LIM-only protein FHL3 to the distal end of the short arm of human chromosome 1.
Somatic cell and molecular genetics 1998;24(3):197-202.
1998: MM Garcia-Barcelo; Stephen Kwok-Wing Tsui; Stephen S C Chim; Kwok-Pui Fung; Cheuk Yu Lee; Mary Waye
Mapping of the human cysteine-rich intestinal protein gene CRIP1 to the human chromosomal segment 7q11.23.
Genomics 1998;47(3):419-22.