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Bice Chini

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TOP 3
Marta Busnelli; Giovanna Mantovani; Erika Peverelli; Anna Spada; Bice Chini
Deciphering the specific role of G(αi/o) isoforms: functional selective oxytocin ligands and somatostatin SST5 receptor mutants.
Mariaelvina Sala; Daniela Braida; Elisabetta Bulgheroni; M Busnelli; A Donzelli; R Martucci; K Nishimori; Daniela Parolaro; Tiziana Rubino; Bice Chini
Mice heterozygous for the oxytocin receptor gene (Oxtr(+/-)) show impaired social behaviour but not increased aggression or cognitive inflexibility: evidence of a selective haploinsufficiency gene effect.
Erika Peverelli; Eleonora Vitali; Paolo Beck-Peccoz; Marta Busnelli; Bice Chini; Celine Gales; Elena Giardino; Andrea G Lania; Giovanna Mantovani; Anna Spada
Specific roles of G(i) protein family members revealed by dissecting SST5 coupling in human pituitary cells.

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All Publications

2013: Marta Busnelli; Giovanna Mantovani; Erika Peverelli; Anna Spada; Bice Chini
Deciphering the specific role of G(αi/o) isoforms: functional selective oxytocin ligands and somatostatin SST5 receptor mutants.
Biochemical Society transactions 2013;41(1):166-71.
2013: Mariaelvina Sala; Daniela Braida; Elisabetta Bulgheroni; M Busnelli; A Donzelli; R Martucci; K Nishimori; Daniela Parolaro; Tiziana Rubino; Bice Chini
Mice heterozygous for the oxytocin receptor gene (Oxtr(+/-)) show impaired social behaviour but not increased aggression or cognitive inflexibility: evidence of a selective haploinsufficiency gene effect.
Journal of neuroendocrinology 2013;25(2):107-18.
2013: Erika Peverelli; Eleonora Vitali; Paolo Beck-Peccoz; Marta Busnelli; Bice Chini; Celine Gales; Elena Giardino; Andrea G Lania; Giovanna Mantovani; Anna Spada
Specific roles of G(i) protein family members revealed by dissecting SST5 coupling in human pituitary cells.
Journal of cell science 2013;126(Pt 2):638-44.
2013: Valérie Capra; Bice Chini; Celine Gales; Alessandro Perenna; Maria Rosa Accomazzo; Manuela Ambrosio; Marta Busnelli; G Enrico Rovati
Full and partial agonists of thromboxane prostanoid receptor unveil fine tuning of receptor superactive conformation and G protein activation.
PloS one 2013;8(3):e60475.
2013: Marta Busnelli; Mario Mauri; Marco Parenti; Bice Chini
Analysis of GPCR dimerization using acceptor photobleaching resonance energy transfer techniques.
Methods in enzymology 2013;521():311-27.
2012: Daniela Braida; Marta Busnelli; Valeria Capurro; Bice Chini; Andrea Donzelli; Roberta Martucci; Mariaelvina Sala
Neurohypophyseal hormones manipulation modulate social and anxiety-related behavior in zebrafish.
Psychopharmacology 2012;220(2):319-30.
2012: Marta Busnelli; Celine Gales; Maurice Manning; Aude Saulière; Michel Bouvier; Bice Chini
Functional selective oxytocin-derived agonists discriminate between individual G protein family subtypes.
The Journal of biological chemistry 2012;287(6):3617-29.
2011: Mariaelvina Sala; Daniela Braida; Daniela Lentini; Marta Busnelli; Elisabetta Bulgheroni; Valeria Capurro; Annamaria Finardi; Andrea Donzelli; Linda Pattini; Tiziana Rubino; Daniela Parolaro; Katsuhiko Nishimori; Marco Parenti; Bice Chini
Pharmacologic rescue of impaired cognitive flexibility, social deficits, increased aggression, and seizure susceptibility in oxytocin receptor null mice: a neurobehavioral model of autism.
Biological psychiatry 2011;69(9):875-82.
2008: Marco Cattaneo; Bice Chini; Lucia Maria Vicentini
Oxytocin stimulates migration and invasion in human endothelial cells.
British journal of pharmacology 2008;153(4):728-36.
2007: Bice Chini; Maurice Manning
Agonist selectivity in the oxytocin/vasopressin receptor family: new insights and challenges.
Biochemical Society transactions 2007;35(Pt 4):737-41.
2006: Alessandra Reversi; Valeria Rimoldi; Silvia Brambillasca; Bice Chini
Effects of cholesterol manipulation on the signaling of the human oxytocin receptor.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;291(4):R861-9.
2005: Alessandra Reversi; Paola Cassoni; Bice Chini
Oxytocin receptor signaling in myoepithelial and cancer cells.
Journal of mammary gland biology and neoplasia 2005;10(3):221-9.
2005: Alessandra Reversi; Valeria Rimoldi; Tiziana Marrocco; Paola Cassoni; Giovanni Bussolati; Marco Parenti; Bice Chini
The oxytocin receptor antagonist atosiban inhibits cell growth via a "biased agonist" mechanism.
The Journal of biological chemistry 2005;280(16):16311-8.
2004: Paola Cassoni; Anna Sapino; Tiziana Marrocco; Bice Chini; Gianni Bussolati
Oxytocin and oxytocin receptors in cancer cells and proliferation.
Journal of neuroendocrinology 2004;16(4):362-4.
2004: Bice Chini; Marco Parenti
G-protein coupled receptors in lipid rafts and caveolae: how, when and why do they go there?
Journal of molecular endocrinology 2004;32(2):325-38.
2003: Valeria Rimoldi; Alessandra Reversi; Elena Taverna; Patrizia Rosa; Maura Francolini; Paola Cassoni; Marco Parenti; Bice Chini
Oxytocin receptor elicits different EGFR/MAPK activation patterns depending on its localization in caveolin-1 enriched domains.
Oncogene 2003;22(38):6054-60.
2003: Bice Chini; Marco Chinol; Paola Cassoni; Stefano Papi; Alessandra Reversi; L Areces; Tiziana Marrocco; Giovanni Paganelli; Maurice Manning; Gianni Bussolati
Improved radiotracing of oxytocin receptor-expressing tumours using the new [111In]-DOTA-Lys8-deamino-vasotocin analogue.
British journal of cancer 2003;89(5):930-6.
2002: Francesca Guzzi; Deborah Zanchetta; Paola Cassoni; Valeria Guzzi; Maura Francolini; Marco Parenti; Bice Chini
Localization of the human oxytocin receptor in caveolin-1 enriched domains turns the receptor-mediated inhibition of cell growth into a proliferative response.
Oncogene 2002;21(11):1658-67.
2001: Gianni Bussolati; Marco Chinol; Bice Chini; A Nacca; Paola Cassoni; Giovanni Paganelli
111In-labeled 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid-lys(8)-vasotocin: a new powerful radioligand for oxytocin receptor-expressing tumors.
Cancer research 2001;61(11):4393-7.
2001: Francesca Guzzi; Deborah Zanchetta; Bice Chini; Marco Parenti
Thioacylation is required for targeting G-protein subunit G(o1alpha) to detergent-insoluble caveolin-containing membrane domains.
The Biochemical journal 2001;355(Pt 2):323-31.
2001: Paola Cassoni; Anna Sapino; Luca Munaron; Silvia Deaglio; Bice Chini; Andrea Graziani; A Ahmed; Gianni Bussolati
Activation of functional oxytocin receptors stimulates cell proliferation in human trophoblast and choriocarcinoma cell lines.
Endocrinology 2001;142(3):1130-6.
2000: E Albertazzi; Deborah Zanchetta; Pascaline VAEZ-OLIVERA; S Faranda; Annalisa Frattini; Paolo Vezzoni; Mirella Procaccio; Alberto Bettinelli; Francesca Guzzi; Marco Parenti; Bice Chini
Nephrogenic diabetes insipidus: functional analysis of new AVPR2 mutations identified in Italian families.
Journal of the American Society of Nephrology : JASN 2000;11(6):1033-43.
2000: Bice Chini; Francesca Fanelli
Molecular basis of ligand binding and receptor activation in the oxytocin and vasopressin receptor family.
Experimental physiology 2000;85 Spec No():59S-66S.
1999: Francesca Fanelli; Pascaline VAEZ-OLIVERA; Deborah Zanchetta; Pier G De Benedetti; Bice Chini
Activation mechanism of human oxytocin receptor: a combined study of experimental and computer-simulated mutagenesis.
Molecular pharmacology 1999;56(1):214-25.
1999: Marcel Hibert; J Hoflack; S Trumpp-Kallmeyer; Bernard Mouillac; Bice Chini; E Mahé; N Cotte; S Jard; Maurice Manning; Claude Barberis
Functional architecture of vasopressin/oxytocin receptors.
Journal of receptor and signal transduction research 1999;19(1-4):589-96.
1998: Bice Chini; E Albertazzi; Pier G De Benedetti; Francesca Fanelli
Identification of a constitutively active mutant of the human oxytocin receptor.
Advances in experimental medicine and biology 1998;449():367-9.
1997: Paola Cassoni; Anna Sapino; Nicoletta Fortunati; Luca Munaron; Bice Chini; Gianni Bussolati
Oxytocin inhibits the proliferation of MDA-MB231 human breast-cancer cells via cyclic adenosine monophosphate and protein kinase A.
International journal of cancer. Journal international du cancer 1997;72(2):340-4.
1997: Bice Chini; Bernard Mouillac; Y Ala; Marie-Noëlle Balestre; S Trumpp-Kallmeyer; J Hoflack; J Elands; Marcel Hibert; Maurice Manning; S Jard; Claude Barberis
Identification of a single residue responsible for agonist selectivity in the oxytocin-vasopressin receptors.
Annals of the New York Academy of Sciences 1997;812():218-21.
1996: Bice Chini; Bernard Mouillac; Marie-Noëlle Balestre; S Trumpp-Kallmeyer; J Hoflack; Marcel Hibert; M Andriolo; S Pupier; S Jard; Claude Barberis
Two aromatic residues regulate the response of the human oxytocin receptor to the partial agonist arginine vasopressin.
FEBS letters 1996;397(2-3):201-6.
1995: Bernard Mouillac; Bice Chini; Marie-Noëlle Balestre; J Elands; S Trumpp-Kallmeyer; J Hoflack; Marcel Hibert; S Jard; Claude Barberis
The binding site of neuropeptide vasopressin V1a receptor. Evidence for a major localization within transmembrane regions.
The Journal of biological chemistry 1995;270(43):25771-7.
1995: S Trumpp-Kallmeyer; Bice Chini; Bernard Mouillac; Claude Barberis; J Hoflack; Marcel Hibert
Towards understanding the role of the first extracellular loop for the binding of peptide hormones to G-protein coupled receptors.
Pharmaceutica acta Helvetiae 1995;70(3):255-62.
1995: Bice Chini; Bernard Mouillac; Y Ala; Marie-Noëlle Balestre; S Trumpp-Kallmeyer; J Hoflack; J Elands; Marcel Hibert; Maurice Manning; S Jard
Tyr115 is the key residue for determining agonist selectivity in the V1a vasopressin receptor.
The EMBO journal 1995;14(10):2176-82.
1995: Bice Chini; Bernard Mouillac; Y Ala; Marie-Noëlle Balestre; N Cotte; S Trumpp-Kallmeyer; J Hoflack; J Elands; Marcel Hibert; Maurice Manning
Molecular basis for agonist selectivity in the vasopressin/oxytocin receptor family.
Advances in experimental medicine and biology 1995;395():321-8.
1995: Bernard Mouillac; Bice Chini; Marie-Noëlle Balestre; S Jard; Claude Barberis; Maurice Manning; Eliane Tribollet; S Trumpp-Kallmeyer; J Hoflack; J Elands
Identification of agonist binding sites of vasopressin and oxytocin receptors.
Advances in experimental medicine and biology 1995;395():301-10.