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Arul Chinnaiyan

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Brenner J Chad; Chinnaiyan Arul M
Translocations in epithelial cancers.
Wang Xiao-Song; Prensner John R; Chen Guoan; Cao Qi; Han Bo; Dhanasekaran Saravana M; Ponnala Rakesh; Cao Xuhong; Varambally Sooryanarayana; Thomas Dafydd G; Giordano Thomas J; Beer David G; Palanisamy Nallasivam; Sartor Maureen A; Omenn Gilbert S; Chinnaiyan Arul M
An integrative approach to reveal driver gene fusions from paired-end sequencing data in cancer.
Gust Kilian M; Hofer Matthias D; Perner Sven R; Kim Robert; Chinnaiyan Arul M; Varambally Sooryanarayana; Moller Peter; Rinnab Ludwig; Rubin Mark A; Greiner Jochen; Schmitt Michael; Kuefer Rainer; Ringhoffer Mark
RHAMM (CD168) is overexpressed at the protein level and may constitute an immunogenic antigen in advanced prostate cancer disease.

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All Publications

2009: Brenner J Chad; Chinnaiyan Arul M
Translocations in epithelial cancers.
Biochimica et biophysica acta 2009;1796(2):201-15.
2009: Wang Xiao-Song; Prensner John R; Chen Guoan; Cao Qi; Han Bo; Dhanasekaran Saravana M; Ponnala Rakesh; Cao Xuhong; Varambally Sooryanarayana; Thomas Dafydd G; Giordano Thomas J; Beer David G; Palanisamy Nallasivam; Sartor Maureen A; Omenn Gilbert S; Chinnaiyan Arul M
An integrative approach to reveal driver gene fusions from paired-end sequencing data in cancer.
Nature biotechnology 2009;27(11):1005-11.
2009: Gust Kilian M; Hofer Matthias D; Perner Sven R; Kim Robert; Chinnaiyan Arul M; Varambally Sooryanarayana; Moller Peter; Rinnab Ludwig; Rubin Mark A; Greiner Jochen; Schmitt Michael; Kuefer Rainer; Ringhoffer Mark
RHAMM (CD168) is overexpressed at the protein level and may constitute an immunogenic antigen in advanced prostate cancer disease.
Neoplasia (New York, N.Y.) 2009;11(9):956-63.
2009: Wang Rou; Chinnaiyan Arul M; Dunn Rodney L; Wojno Kirk J; Wei John T
Rational approach to implementation of prostate cancer antigen 3 into clinical care.
Cancer 2009;115(17):3879-86.
2009: Han Bo; Mehra Rohit; Suleman Khalid; Tomlins Scott A; Wang Lei; Singhal Nishi; Linetzky Katherine A; Palanisamy Nallasivam; Zhou Ming; Chinnaiyan Arul M; Shah Rajal B
Characterization of ETS gene aberrations in select histologic variants of prostate carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009;22(9):1176-85.
2009: Khodadoust Michael S; Verhaegen Monique; Kappes Ferdinand; Riveiro-Falkenbach Erica; Cigudosa Juan C; Kim David S L; Chinnaiyan Arul M; Markovitz David M; Soengas María S
Melanoma proliferation and chemoresistance controlled by the DEK oncogene.
Cancer research 2009;69(16):6405-13.
2009: Tomlins Scott A; Bjartell Anders; Chinnaiyan Arul M; Jenster Guido; Nam Robert K; Rubin Mark A; Schalken Jack A
ETS gene fusions in prostate cancer: from discovery to daily clinical practice.
European urology 2009;56(2):275-86.
2009: Han Bo; Mehra Rohit; Lonigro Robert J; Wang Lei; Suleman Khalid; Menon Anjana; Palanisamy Nallasivam; Tomlins Scott A; Chinnaiyan Arul M; Shah Rajal B
Fluorescence in situ hybridization study shows association of PTEN deletion with ERG rearrangement during prostate cancer progression.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009;22(8):1083-93.
2009: Wang Qianben; Li Wei; Zhang Yong; Yuan Xin; Xu Kexin; Yu Jindan; Chen Zhong; Beroukhim Rameen; Wang Hongyun; Lupien Mathieu; Wu Tao; Regan Meredith M; Meyer Clifford A; Carroll Jason S; Manrai Arjun Kumar; Jänne Olli A; Balk Steven P; Mehra Rohit; Han Bo; Chinnaiyan Arul M; Rubin Mark A; True Lawrence; Fiorentino Michelangelo; Fiore Christopher; Loda Massimo; Kantoff Philip W; Liu X Shirley; Brown Myles
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer.
Cell 2009;138(2):245-56.
2009: Maher Christopher A; Palanisamy Nallasivam; Brenner John C; Cao Xuhong; Kalyana-Sundaram Shanker; Luo Shujun; Khrebtukova Irina; Barrette Terrence R; Grasso Catherine; Yu Jindan; Lonigro Robert J; Schroth Gary; Kumar-Sinha Chandan; Chinnaiyan Arul M
Chimeric transcript discovery by paired-end transcriptome sequencing.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(30):12353-8.
2009: Mosquera Juan-Miguel; Mehra Rohit; Regan Meredith M; Perner Sven; Genega Elizabeth M; Bueti Gerri; Shah Rajal B; Gaston Sandra; Tomlins Scott A; Wei John T; Kearney Michael C; Johnson Laura A; Tang Jeffrey M; Chinnaiyan Arul M; Rubin Mark A; Sanda Martin G
Prevalence of TMPRSS2-ERG fusion prostate cancer among men undergoing prostate biopsy in the United States.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(14):4706-11.
2009: Lee Inhan; Ajay Subramanian S; Yook Jong In; Kim Hyun Sil; Hong Su Hyung; Kim Nam Hee; Dhanasekaran Saravana M; Chinnaiyan Arul M; Athey Brian D
New class of microRNA targets containing simultaneous 5'-UTR and 3'-UTR interaction sites.
Genome research 2009;19(7):1175-83.
2009: Rhodes Daniel R; Ateeq Bushra; Cao Qi; Tomlins Scott A; Mehra Rohit; Laxman Bharathi; Kalyana-Sundaram Shanker; Lonigro Robert J; Helgeson Beth E; Bhojani Mahaveer S; Rehemtulla Alnawaz; Kleer Celina G; Hayes Daniel F; Lucas Peter C; Varambally Sooryanarayana; Chinnaiyan Arul M
AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(25):10284-9.
2009: Kim You Jung; Teletia Nikhil; Ruotti Victor; Maher Christopher A; Chinnaiyan Arul M; Stewart Ron; Thomson James A; Patel Jignesh M
ProbeMatch: rapid alignment of oligonucleotides to genome allowing both gaps and mismatches.
Bioinformatics (Oxford, England) 2009;25(11):1424-5.
2009: Grubb Robert L; Deng Jianghong; Pinto Peter A; Mohler James L; Chinnaiyan Arul; Rubin Mark; Linehan W Marston; Liotta Lance A; Petricoin Emanuel F; Wulfkuhle Julia D
Pathway biomarker profiling of localized and metastatic human prostate cancer reveal metastatic and prognostic signatures.
Journal of proteome research 2009;8(6):3044-54.
2009: Shah Rajal B; Chinnaiyan Arul M
The discovery of common recurrent transmembrane protease serine 2 (TMPRSS2)-erythroblastosis virus E26 transforming sequence (ETS) gene fusions in prostate cancer: significance and clinical implications.
Advances in anatomic pathology 2009;16(3):145-53.
2009: Wang Rou; Morris David S; Tomlins Scott A; Lonigro Robert J; Tsodikov Alexander; Mehra Rohit; Giordano Thomas J; Kunju L Priya; Lee Cheryl T; Weizer Alon Z; Chinnaiyan Arul M
Development of a multiplex quantitative PCR signature to predict progression in non-muscle-invasive bladder cancer.
Cancer research 2009;69(9):3810-8.
2009: Steinkamp Mara P; O'Mahony Orla A; Brogley Michele; Rehman Haniya; Lapensee Elizabeth W; Dhanasekaran Saravana; Hofer Matthias D; Kuefer Rainer; Chinnaiyan Arul; Rubin Mark A; Pienta Kenneth J; Robins Diane M
Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy.
Cancer research 2009;69(10):4434-42.
2009: Yocum Anastasia K; Chinnaiyan Arul M
Current affairs in quantitative targeted proteomics: multiple reaction monitoring-mass spectrometry.
Briefings in functional genomics & proteomics 2009;8(2):145-57.
2009: Maher Christopher A; Kumar-Sinha Chandan; Cao Xuhong; Kalyana-Sundaram Shanker; Han Bo; Jing Xiaojun; Sam Lee; Barrette Terrence; Palanisamy Nallasivam; Chinnaiyan Arul M
Transcriptome sequencing to detect gene fusions in cancer.
Nature 2009;458(7234):97-101.
2009: Prensner John R; Chinnaiyan Arul M
Oncogenic gene fusions in epithelial carcinomas.
Current opinion in genetics & development 2009;19(1):82-91.
2009: Sreekumar Arun; Poisson Laila M; Rajendiran Thekkelnaycke M; Khan Amjad P; Cao Qi; Yu Jindan; Laxman Bharathi; Mehra Rohit; Lonigro Robert J; Li Yong; Nyati Mukesh K; Ahsan Aarif; Kalyana-Sundaram Shanker; Han Bo; Cao Xuhong; Byun Jaeman; Omenn Gilbert S; Ghosh Debashis; Pennathur Subramaniam; Alexander Danny C; Berger Alvin; Shuster Jeffrey R; Wei John T; Varambally Sooryanarayana; Beecher Christopher; Chinnaiyan Arul M
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.
Nature 2009;457(7231):910-4.
2009: Bedolla Roble G; Wang Yu; Asuncion Alfredo; Chamie Karim; Siddiqui Salma; Mudryj Maria M; Prihoda Thomas J; Siddiqui Javed; Chinnaiyan Arul M; Mehra Rohit; de Vere White Ralph W; Ghosh Paramita M
Nuclear versus cytoplasmic localization of filamin A in prostate cancer: immunohistochemical correlation with metastases.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(3):788-96.
2009: Worzel William P; Yu Jianjun; Almal Arpit A; Chinnaiyan Arul M
Applications of genetic programming in cancer research.
The international journal of biochemistry & cell biology 2009;41(2):405-13.
2009: Ghosh Debashis; Chinnaiyan Arul M
Genomic outlier profile analysis: mixture models, null hypotheses, and nonparametric estimation.
Biostatistics (Oxford, England) 2009;10(1):60-9.
2009: Vellaichamy Adaikkalam; Sreekumar Arun; Strahler John R; Rajendiran Theckelnaycke; Yu Jindan; Varambally Sooryanarayana; Li Yong; Omenn Gilbert S; Chinnaiyan Arul M; Nesvizhskii Alexey I
Proteomic interrogation of androgen action in prostate cancer cells reveals roles of aminoacyl tRNA synthetases.
PloS one 2009;4(9):e7075.
2009: Hanauer David A; Rhodes Daniel R; Chinnaiyan Arul M
Exploring clinical associations using '-omics' based enrichment analyses.
PloS one 2009;4(4):e5203.
2008: Varambally Sooryanarayana; Cao Qi; Mani Ram-Shankar; Shankar Sunita; Wang Xiaosong; Ateeq Bushra; Laxman Bharathi; Cao Xuhong; Jing Xiaojun; Ramnarayanan Kalpana; Brenner J Chad; Yu Jindan; Kim Jung H; Han Bo; Tan Patrick; Kumar-Sinha Chandan; Lonigro Robert J; Palanisamy Nallasivam; Maher Christopher A; Chinnaiyan Arul M
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer.
Science (New York, N.Y.) 2008;322(5908):1695-9.
2008: Cao Q; Yu J; Dhanasekaran S M; Kim J H; Mani R-S; Tomlins S A; Mehra R; Laxman B; Cao X; Yu J; Kleer C G; Varambally S; Chinnaiyan A M
Repression of E-cadherin by the polycomb group protein EZH2 in cancer.
Oncogene 2008;27(58):7274-84.
2008: Albertus Daniel L; Seder Christopher W; Chen Guoan; Wang Xiaoju; Hartojo Wibisono; Lin Lin; Silvers Amy; Thomas Daffyd G; Giordano Thomas J; Chang Andrew C; Orringer Mark B; Bigbee William L; Chinnaiyan Arul M; Beer David G
AZGP1 autoantibody predicts survival and histone deacetylase inhibitors increase expression in lung adenocarcinoma.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008;3(11):1236-44.
2008: Varambally Sooryanarayana; Laxman Bharathi; Mehra Rohit; Cao Qi; Dhanasekaran Saravana M; Tomlins Scott A; Granger Jill; Vellaichamy Adaikkalam; Sreekumar Arun; Yu Jianjun; Gu Wenjuan; Shen Ronglai; Ghosh Debashis; Wright Lorinda M; Kladney Raleigh D; Kuefer Rainer; Rubin Mark A; Fimmel Claus J; Chinnaiyan Arul M
Golgi protein GOLM1 is a tissue and urine biomarker of prostate cancer.
Neoplasia (New York, N.Y.) 2008;10(11):1285-94.
2008: Han Bo; Mehra Rohit; Dhanasekaran Saravana M; Yu Jindan; Menon Anjana; Lonigro Robert J; Wang Xiaosong; Gong Yusong; Wang Lei; Shankar Sunita; Laxman Bharathi; Shah Rajal B; Varambally Sooryanarayana; Palanisamy Nallasivam; Tomlins Scott A; Kumar-Sinha Chandan; Chinnaiyan Arul M
A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer.
Cancer research 2008;68(18):7629-37.
2008: Woods Ignatoski Kathleen M; Grewal Navdeep K; Markwart Sonja M; Vellaichamy Adaikkalam; Chinnaiyan Arul M; Yeung Kam; Ray Michael E; Keller Evan T
Loss of Raf kinase inhibitory protein induces radioresistance in prostate cancer.
International journal of radiation oncology, biology, physics 2008;72(1):153-60.
2008: Tseng-Rogenski Stephanie S; Arredouani Mohamed S; Neeley Yilin C; Lu Bin; Chinnaiyan Arul M; Sanda Martin G
Fas-mediated T cell deletion potentiates tumor antigen-specific tolerance in a mouse model of prostate cancer.
Cancer immunology, immunotherapy : CII 2008;57(9):1357-65.
2008: van Golen Kenneth L; Ying Chi; Sequeira Linda; Dubyk Cara W; Reisenberger Tracy; Chinnaiyan Arul M; Pienta Kenneth J; Loberg Robert D
CCL2 induces prostate cancer transendothelial cell migration via activation of the small GTPase Rac.
Journal of cellular biochemistry 2008;104(5):1587-97.
2008: Narla Goutham; DiFeo Analisa; Fernandez Yolanda; Dhanasekaran Saravana; Huang Fei; Sangodkar Jaya; Hod Eldad; Leake Devin; Friedman Scott L; Hall Simon J; Chinnaiyan Arul M; Gerald William L; Rubin Mark A; Martignetti John A
KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis.
The Journal of clinical investigation 2008;118(8):2711-21.
2008: Morris David S; Tomlins Scott A; Montie James E; Chinnaiyan Arul M
The discovery and application of gene fusions in prostate cancer.
BJU international 2008;102(3):276-82.
2008: Zhao Bin; Ye Xin; Yu Jindan; Li Li; Li Weiquan; Li Siming; Yu Jianjun; Lin Jiandie D; Wang Cun-Yu; Chinnaiyan Arul M; Lai Zhi-Chun; Guan Kun-Liang
TEAD mediates YAP-dependent gene induction and growth control.
Genes & development 2008;22(14):1962-71.
2008: Kumar-Sinha Chandan; Tomlins Scott A; Chinnaiyan Arul M
Recurrent gene fusions in prostate cancer.
Nature reviews. Cancer 2008;8(7):497-511.
2008: Tomlins Scott A; Rhodes Daniel R; Yu Jianjun; Varambally Sooryanarayana; Mehra Rohit; Perner Sven; Demichelis Francesca; Helgeson Beth E; Laxman Bharathi; Morris David S; Cao Qi; Cao Xuhong; Andrén Ove; Fall Katja; Johnson Laura; Wei John T; Shah Rajal B; Al-Ahmadie Hikmat; Eastham James A; Eggener Scott E; Fine Samson W; Hotakainen Kristina; Stenman Ulf-Håkan; Tsodikov Alex; Gerald William L; Lilja Hans; Reuter Victor E; Kantoff Phillip W; Scardino Peter T; Rubin Mark A; Bjartell Anders S; Chinnaiyan Arul M
The role of SPINK1 in ETS rearrangement-negative prostate cancers.
Cancer cell 2008;13(6):519-28.
2008: Setlur Sunita R; Mertz Kirsten D; Hoshida Yujin; Demichelis Francesca; Lupien Mathieu; Perner Sven; Sboner Andrea; Pawitan Yudi; Andrén Ove; Johnson Laura A; Tang Jeff; Adami Hans-Olov; Calza Stefano; Chinnaiyan Arul M; Rhodes Daniel; Tomlins Scott; Fall Katja; Mucci Lorelei A; Kantoff Philip W; Stampfer Meir J; Andersson Swen-Olof; Varenhorst Eberhard; Johansson Jan-Erik; Brown Myles; Golub Todd R; Rubin Mark A
Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer.
Journal of the National Cancer Institute 2008;100(11):815-25.
2008: Mehra Rohit; Tomlins Scott A; Yu Jianjun; Cao Xuhong; Wang Lei; Menon Anjana; Rubin Mark A; Pienta Kenneth J; Shah Rajal B; Chinnaiyan Arul M
Characterization of TMPRSS2-ETS gene aberrations in androgen-independent metastatic prostate cancer.
Cancer research 2008;68(10):3584-90.
2008: Huang Wei; Zhang Yanhong; Varambally Sooryanarayana; Chinnaiyan Arul M; Banerjee Mousumi; Merajver Sofia D; Kleer Celina G
Inhibition of CCN6 (Wnt-1-induced signaling protein 3) down-regulates E-cadherin in the breast epithelium through induction of snail and ZEB1.
The American journal of pathology 2008;172(4):893-904.
2008: Mullins Chris; Lucia M Scott; Hayward Simon W; Lee Jeannette Y; Levitt Jonathan M; Lin Victor K; Liu Brian C-S; Chinnaiyan Arul M; Rubin Mark A; Slawin Kevin; Star Robert A; Getzenberg Robert H;
A comprehensive approach toward novel serum biomarkers for benign prostatic hyperplasia: the MPSA Consortium.
The Journal of urology 2008;179(4):1243-56.
2008: Joshua A M; Evans A; Van der Kwast T; Zielenska M; Meeker A K; Chinnaiyan A; Squire J A
Prostatic preneoplasia and beyond.
Biochimica et biophysica acta 2008;1785(2):156-81.
2008: Perner Sven; Wagner Patrick L; Demichelis Francesca; Mehra Rohit; Lafargue Christopher J; Moss Benjamin J; Arbogast Stefanie; Soltermann Alex; Weder Walter; Giordano Thomas J; Beer David G; Rickman David S; Chinnaiyan Arul M; Moch Holger; Rubin Mark A
EML4-ALK fusion lung cancer: a rare acquired event.
Neoplasia (New York, N.Y.) 2008;10(3):298-302.
2008: Begley Lesa A; Kasina Sathish; Mehra Rohit; Adsule Shreelekha; Admon Andrew J; Lonigro Robert J; Chinnaiyan Arul M; Macoska Jill A
CXCL5 promotes prostate cancer progression.
Neoplasia (New York, N.Y.) 2008;10(3):244-54.
2008: Taylor Barry S; Pal Manoj; Yu Jianjun; Laxman Bharathi; Kalyana-Sundaram Shanker; Zhao Rong; Menon Anjana; Wei John T; Nesvizhskii Alexey I; Ghosh Debashis; Omenn Gilbert S; Lubman David M; Chinnaiyan Arul M; Sreekumar Arun
Humoral response profiling reveals pathways to prostate cancer progression.
Molecular & cellular proteomics : MCP 2008;7(3):600-11.
2008: Tomlins Scott A; Laxman Bharathi; Varambally Sooryanarayana; Cao Xuhong; Yu Jindan; Helgeson Beth E; Cao Qi; Prensner John R; Rubin Mark A; Shah Rajal B; Mehra Rohit; Chinnaiyan Arul M
Role of the TMPRSS2-ERG gene fusion in prostate cancer.
Neoplasia (New York, N.Y.) 2008;10(2):177-88.
2008: Laxman Bharathi; Morris David S; Yu Jianjun; Siddiqui Javed; Cao Jie; Mehra Rohit; Lonigro Robert J; Tsodikov Alex; Wei John T; Tomlins Scott A; Chinnaiyan Arul M
A first-generation multiplex biomarker analysis of urine for the early detection of prostate cancer.
Cancer research 2008;68(3):645-9.
2008: Yu Jianjun; Yu Jindan; Cordero Kevin E; Johnson Michael D; Ghosh Debashis; Rae James M; Chinnaiyan Arul M; Lippman Marc E
A transcriptional fingerprint of estrogen in human breast cancer predicts patient survival.
Neoplasia (New York, N.Y.) 2008;10(1):79-88.
2008: Helgeson Beth E; Tomlins Scott A; Shah Nameeta; Laxman Bharathi; Cao Qi; Prensner John R; Cao Xuhong; Singla Nirmish; Montie James E; Varambally Sooryanarayana; Mehra Rohit; Chinnaiyan Arul M
Characterization of TMPRSS2:ETV5 and SLC45A3:ETV5 gene fusions in prostate cancer.
Cancer research 2008;68(1):73-80.
2008: Lippman Marc E; Rae James M; Chinnaiyan Arul M
An expression signature of estrogen-regulated genes predicts disease-free survival in tamoxifen-treated patients better than progesterone receptor status.
Transactions of the American Clinical and Climatological Association 2008;119():77-90; discussion 90-2.
2008: Shen Ronglai; Chinnaiyan Arul M; Ghosh Debashis
Pathway analysis reveals functional convergence of gene expression profiles in breast cancer.
BMC medical genomics 2008;1():28.
2007: Nikiforov Mikhail A; Riblett Marybeth; Tang Wen-Hua; Gratchouck Vladimir; Zhuang Dazhong; Fernandez Yolanda; Verhaegen Monique; Varambally Sooryanarayana; Chinnaiyan Arul M; Jakubowiak Andrzej J; Soengas Maria S
Tumor cell-selective regulation of NOXA by c-MYC in response to proteasome inhibition.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(49):19488-93.
2007: Mueller Dorothee; Bach Christian; Zeisig Deniz; Garcia-Cuellar Maria-Paz; Monroe Sara; Sreekumar Arun; Zhou Rong; Nesvizhskii Alexey; Chinnaiyan Arul; Hess Jay L; Slany Robert K
A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification.
Blood 2007;110(13):4445-54.
2007: Yu Jindan; Yu Jianjun; Rhodes Daniel R; Tomlins Scott A; Cao Xuhong; Chen Guoan; Mehra Rohit; Wang Xiaoju; Ghosh Debashis; Shah Rajal B; Varambally Sooryanarayana; Pienta Kenneth J; Chinnaiyan Arul M
A polycomb repression signature in metastatic prostate cancer predicts cancer outcome.
Cancer research 2007;67(22):10657-63.
2007: Yu Jindan; Cao Qi; Mehra Rohit; Laxman Bharathi; Yu Jianjun; Tomlins Scott A; Creighton Chad J; Dhanasekaran Saravana M; Shen Ronglai; Chen Guoan; Morris David S; Marquez Victor E; Shah Rajal B; Ghosh Debashis; Varambally Sooryanarayana; Chinnaiyan Arul M
Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer.
Cancer cell 2007;12(5):419-31.
2007: Zhao Bin; Wei Xiaomu; Li Weiquan; Udan Ryan S; Yang Qian; Kim Joungmok; Xie Joe; Ikenoue Tsuneo; Yu Jindan; Li Li; Zheng Pan; Ye Keqiang; Chinnaiyan Arul; Halder Georg; Lai Zhi-Chun; Guan Kun-Liang
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.
Genes & development 2007;21(21):2747-61.
2007: Hanauer David A; Miela Gretchen; Chinnaiyan Arul M; Chang Alfred E; Blayney Douglas W
The registry case finding engine: an automated tool to identify cancer cases from unstructured, free-text pathology reports and clinical notes.
Journal of the American College of Surgeons 2007;205(5):690-7.
2007: Kim Jung H; Dhanasekaran Saravana M; Mehra Rohit; Tomlins Scott A; Gu Wenjuan; Yu Jianjun; Kumar-Sinha Chandan; Cao Xuhong; Dash Atreya; Wang Lei; Ghosh Debashis; Shedden Kerby; Montie James E; Rubin Mark A; Pienta Kenneth J; Shah Rajal B; Chinnaiyan Arul M
Integrative analysis of genomic aberrations associated with prostate cancer progression.
Cancer research 2007;67(17):8229-39.
2007: Mehra Rohit; Han Bo; Tomlins Scott A; Wang Lei; Menon Anjana; Wasco Matthew J; Shen Ronglai; Montie James E; Chinnaiyan Arul M; Shah Rajal B
Heterogeneity of TMPRSS2 gene rearrangements in multifocal prostate adenocarcinoma: molecular evidence for an independent group of diseases.
Cancer research 2007;67(17):7991-5.
2007: Schmidt F; Bittinger F; Chinnaiyan A M; Rubin M A
[Developing a molecular marker profile for prognosis of the course of benign prostatic hyperplasia]
Der Urologe. Ausg. A 2007;46(9):1188-9.
2007: Wang Qianben; Li Wei; Liu X Shirley; Carroll Jason S; Jänne Olli A; Keeton Erika Krasnickas; Chinnaiyan Arul M; Pienta Kenneth J; Brown Myles
A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth.
Molecular cell 2007;27(3):380-92.
2007: Tomlins Scott A; Laxman Bharathi; Dhanasekaran Saravana M; Helgeson Beth E; Cao Xuhong; Morris David S; Menon Anjana; Jing Xiaojun; Cao Qi; Han Bo; Yu Jindan; Wang Lei; Montie James E; Rubin Mark A; Pienta Kenneth J; Roulston Diane; Shah Rajal B; Varambally Sooryanarayana; Mehra Rohit; Chinnaiyan Arul M
Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer.
Nature 2007;448(7153):595-9.
2007: Loberg Robert D; Bradley Deborah A; Tomlins Scott A; Chinnaiyan Arul M; Pienta Kenneth J
The lethal phenotype of cancer: the molecular basis of death due to malignancy.
CA: a cancer journal for clinicians 2007;57(4):225-41.
2007: Demichelis F; Fall K; Perner S; Andrén O; Schmidt F; Setlur S R; Hoshida Y; Mosquera J-M; Pawitan Y; Lee C; Adami H-O; Mucci L A; Kantoff P W; Andersson S-O; Chinnaiyan A M; Johansson J-E; Rubin M A
TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort.
Oncogene 2007;26(31):4596-9.
2007: Perner Sven; Mosquera Juan-Miguel; Demichelis Francesca; Hofer Matthias D; Paris Pamela L; Simko Jeff; Collins Colin; Bismar Tarek A; Chinnaiyan Arul M; De Marzo Angelo M; Rubin Mark A
TMPRSS2-ERG fusion prostate cancer: an early molecular event associated with invasion.
The American journal of surgical pathology 2007;31(6):882-8.
2007: Rhodes Daniel R; Kalyana-Sundaram Shanker; Tomlins Scott A; Mahavisno Vasudeva; Kasper Nicole; Varambally Radhika; Barrette Terrence R; Ghosh Debashis; Varambally Sooryanarayana; Chinnaiyan Arul M
Molecular concepts analysis links tumors, pathways, mechanisms, and drugs.
Neoplasia (New York, N.Y.) 2007;9(5):443-54.
2007: Morris David S; Tomlins Scott A; Rhodes Daniel R; Mehra Rohit; Shah Rajal B; Chinnaiyan Arul M
Integrating biomedical knowledge to model pathways of prostate cancer progression.
Cell cycle (Georgetown, Tex.) 2007;6(10):1177-87.
2007: Mosquera J-M; Perner S; Demichelis F; Kim R; Hofer M D; Mertz K D; Paris P L; Simko J; Collins C; Bismar T A; Chinnaiyan A M; Rubin M A
Morphological features of TMPRSS2-ERG gene fusion prostate cancer.
The Journal of pathology 2007;212(1):91-101.
2007: Mehra Rohit; Tomlins Scott A; Shen Ronglai; Nadeem Owais; Wang Lei; Wei John T; Pienta Kenneth J; Ghosh Debashis; Rubin Mark A; Chinnaiyan Arul M; Shah Rajal B
Comprehensive assessment of TMPRSS2 and ETS family gene aberrations in clinically localized prostate cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2007;20(5):538-44.
2007: Feng F Y; Varambally S; Tomlins S A; Chun P Y; Lopez C A; Li X; Davis M A; Chinnaiyan A M; Lawrence T S; Nyati M K
Role of epidermal growth factor receptor degradation in gemcitabine-mediated cytotoxicity.
Oncogene 2007;26(23):3431-9.
2007: Yu Jianjun; Yu Jindan; Almal Arpit A; Dhanasekaran Saravana M; Ghosh Debashis; Worzel William P; Chinnaiyan Arul M
Feature selection and molecular classification of cancer using genetic programming.
Neoplasia (New York, N.Y.) 2007;9(4):292-303.
2007: Chen Guoan; Wang Xiaoju; Yu Jianjun; Varambally Sooryanarayana; Yu Jindan; Thomas Dafydd G; Lin Mu-Yen; Vishnu Prakash; Wang Zhuwen; Wang Rui; Fielhauer Jeff; Ghosh Debashis; Giordano Thomas J; Giacherio Donald; Chang Andrew C; Orringer Mark B; El-Hefnawy Talal; Bigbee William L; Beer David G; Chinnaiyan Arul M
Autoantibody profiles reveal ubiquilin 1 as a humoral immune response target in lung adenocarcinoma.
Cancer research 2007;67(7):3461-7.
2007: Mertz Kirsten D; Setlur Sunita R; Dhanasekaran Saravana M; Demichelis Francesca; Perner Sven; Tomlins Scott; Tchinda Joëlle; Laxman Bharathi; Vessella Robert L; Beroukhim Rameen; Lee Charles; Chinnaiyan Arul M; Rubin Mark A
Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model.
Neoplasia (New York, N.Y.) 2007;9(3):200-6.
2007: Rhodes Daniel R; Kalyana-Sundaram Shanker; Mahavisno Vasudeva; Varambally Radhika; Yu Jianjun; Briggs Benjamin B; Barrette Terrence R; Anstet Matthew J; Kincead-Beal Colleen; Kulkarni Prakash; Varambally Sooryanaryana; Ghosh Debashis; Chinnaiyan Arul M
Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles.
Neoplasia (New York, N.Y.) 2007;9(2):166-80.
2007: Ghosh Debashis; Chinnaiyan Arul M
Empirical Bayes identification [correction of identication] of tumor progression genes from microarray data.
Biometrical journal. Biometrische Zeitschrift 2007;49(1):68-77.
2007: Mathew Jomol P; Taylor Barry S; Bader Gary D; Pyarajan Saiju; Antoniotti Marco; Chinnaiyan Arul M; Sander Chris; Burakoff Steven J; Mishra Bud
From bytes to bedside: data integration and computational biology for translational cancer research.
PLoS computational biology 2007;3(2):e12.
2007: Hanauer David A; Rhodes Daniel R; Sinha-Kumar Chandan; Chinnaiyan Arul M
Bioinformatics approaches in the study of cancer.
Current molecular medicine 2007;7(1):133-41.
2007: Tomlins Scott A; Mehra Rohit; Rhodes Daniel R; Cao Xuhong; Wang Lei; Dhanasekaran Saravana M; Kalyana-Sundaram Shanker; Wei John T; Rubin Mark A; Pienta Kenneth J; Shah Rajal B; Chinnaiyan Arul M
Integrative molecular concept modeling of prostate cancer progression.
Nature genetics 2007;39(1):41-51.
2007: Hanauer David A; Chinnaiyan Arul M
PubMed QUEST: The PubMed Query Search Tool. An informatics tool to aid cancer centers and cancer investigators in searching the PubMed databases.
Cancer informatics 2007;2():79-82.
2007: Hanauer David A; Rhodes Daniel R; Chinnaiyan Arul M
Identifying significant associations using free text problem summary lists in a clinical data repository.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2007;():968.
2007: Choi Hyungwon; Shen Ronglai; Chinnaiyan Arul M; Ghosh Debashis
A latent variable approach for meta-analysis of gene expression data from multiple microarray experiments.
BMC bioinformatics 2007;8():364.
2006: Nyati Mukesh K; Feng Felix Y; Maheshwari Divya; Varambally Sooryanarayana; Zielske Steven P; Ahsan Aarif; Chun Patrick Y; Arora Vinay A; Davis Mary A; Jung Mira; Ljungman Mats; Canman Christine E; Chinnaiyan Arul M; Lawrence Theodore S
Ataxia telangiectasia mutated down-regulates phospho-extracellular signal-regulated kinase 1/2 via activation of MKP-1 in response to radiation.
Cancer research 2006;66(24):11554-9.
2006: Fiskus Warren; Pranpat Michael; Balasis Maria; Herger Bryan; Rao Rekha; Chinnaiyan Arul; Atadja Peter; Bhalla Kapil
Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells.
Molecular cancer therapeutics 2006;5(12):3096-104.
2006: Bradford Timothy J; Tomlins Scott A; Wang Xiaoju; Chinnaiyan Arul M
Molecular markers of prostate cancer.
Urologic oncology 2006;24(6):538-51.
2006: Kumar-Sinha Chandan; Tomlins Scott A; Chinnaiyan Arul M
Evidence of recurrent gene fusions in common epithelial tumors.
Trends in molecular medicine 2006;12(11):529-36.
2006: Rubin Mark A; Chinnaiyan Arul M
Bioinformatics approach leads to the discovery of the TMPRSS2:ETS gene fusion in prostate cancer.
Laboratory investigation; a journal of technical methods and pathology 2006;86(11):1099-102.
2006: Shen Ronglai; Ghosh Debashis; Chinnaiyan Arul; Meng Zhaoling
Eigengene-based linear discriminant model for tumor classification using gene expression microarray data.
Bioinformatics (Oxford, England) 2006;22(21):2635-42.
2006: Laxman Bharathi; Tomlins Scott A; Mehra Rohit; Morris David S; Wang Lei; Helgeson Beth E; Shah Rajal B; Rubin Mark A; Wei John T; Chinnaiyan Arul M
Noninvasive detection of TMPRSS2:ERG fusion transcripts in the urine of men with prostate cancer.
Neoplasia (New York, N.Y.) 2006;8(10):885-8.
2006: Perner Sven; Demichelis Francesca; Beroukhim Rameen; Schmidt Folke H; Mosquera Juan-Miguel; Setlur Sunita; Tchinda Joelle; Tomlins Scott A; Hofer Matthias D; Pienta Kenneth G; Kuefer Rainer; Vessella Robert; Sun Xiao-Wei; Meyerson Matthew; Lee Charles; Sellers William R; Chinnaiyan Arul M; Rubin Mark A
TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer.
Cancer research 2006;66(17):8337-41.
2006: Taylor B S; Varambally S; Chinnaiyan A M
Differential proteomic alterations between localised and metastatic prostate cancer.
British journal of cancer 2006;95(4):425-30.
2006: Tomlins Scott A; Chinnaiyan Arul M
Of mice and men: cancer gene discovery using comparative oncogenomics.
Cancer cell 2006;10(1):2-4.
2006: Haas Christian S; Creighton Chad J; Pi Xiujun; Maine Ira; Koch Alisa E; Haines G Kenneth; Ling Song; Chinnaiyan Arul M; Holoshitz Joseph
Identification of genes modulated in rheumatoid arthritis using complementary DNA microarray analysis of lymphoblastoid B cell lines from disease-discordant monozygotic twins.
Arthritis and rheumatism 2006;54(7):2047-60.
2006: Taylor Barry S; Varambally Sooryanarayana; Chinnaiyan Arul M
A systems approach to model metastatic progression.
Cancer research 2006;66(11):5537-9.
2006: Kumar-Sinha Chandan; Chinnaiyan Arul M
A SLAMS dunk for cancer regulators.
Nature biotechnology 2006;24(5):524-6.
2006: Bradford Timothy J; Wang Xiaoju; Chinnaiyan Arul M
Cancer immunomics: using autoantibody signatures in the early detection of prostate cancer.
Urologic oncology 2006;24(3):237-42.
2006: Kuefer Rainer; Day Kathleen C; Kleer Celina G; Sabel Michael S; Hofer Matthias D; Varambally Sooryanarayana; Zorn Christoph S; Chinnaiyan Arul M; Rubin Mark A; Day Mark L
ADAM15 disintegrin is associated with aggressive prostate and breast cancer disease.
Neoplasia (New York, N.Y.) 2006;8(4):319-29.
2006: Ding Lei; Erdmann Christine; Chinnaiyan Arul M; Merajver Sofia D; Kleer Celina G
Identification of EZH2 as a molecular marker for a precancerous state in morphologically normal breast tissues.
Cancer research 2006;66(8):4095-9.
2006: Giordano Thomas J; Au Amy Y M; Kuick Rork; Thomas Dafydd G; Rhodes Daniel R; Wilhelm Kenneth G; Vinco Michelle; Misek David E; Sanders Donita; Zhu Zhaowen; Ciampi Raffaele; Hanash Samir; Chinnaiyan Arul; Clifton-Bligh Roderick J; Robinson Bruce G; Nikiforov Yuri E; Koenig Ronald J
Delineation, functional validation, and bioinformatic evaluation of gene expression in thyroid follicular carcinomas with the PAX8-PPARG translocation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(7 Pt 1):1983-93.
2006: Creighton Chad J; Hilger Amy M; Murthy Shalini; Rae James M; Chinnaiyan Arul M; El-Ashry Dorraya
Activation of mitogen-activated protein kinase in estrogen receptor alpha-positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor alpha-negative human breast tumors.
Cancer research 2006;66(7):3903-11.
2006: Tomlins Scott A; Mehra Rohit; Rhodes Daniel R; Smith Lisa R; Roulston Diane; Helgeson Beth E; Cao Xuhong; Wei John T; Rubin Mark A; Shah Rajal B; Chinnaiyan Arul M
TMPRSS2:ETV4 gene fusions define a third molecular subtype of prostate cancer.
Cancer research 2006;66(7):3396-400.
2006: Tomlins Scott A; Mehra Rohit; Rhodes Daniel R; Shah Rajal B; Rubin Mark A; Bruening Eric; Makarov Vladimir; Chinnaiyan Arul M
Whole transcriptome amplification for gene expression profiling and development of molecular archives.
Neoplasia (New York, N.Y.) 2006;8(2):153-62.
2006: Pal Manoj; Moffa Allison; Sreekumar Arun; Ethier Stephen P; Barder Timothy J; Chinnaiyan Arul; Lubman David M
Differential phosphoprotein mapping in cancer cells using protein microarrays produced from 2-D liquid fractionation.
Analytical chemistry 2006;78(3):702-10.
2006: Fu Zheng; Kitagawa Yasuhide; Shen Ronglai; Shah Rajal; Mehra Rohit; Rhodes Daniel; Keller Peter J; Mizokami Atsushi; Dunn Rodney; Chinnaiyan Arul M; Yao Zhi; Keller Evan T
Metastasis suppressor gene Raf kinase inhibitor protein (RKIP) is a novel prognostic marker in prostate cancer.
The Prostate 2006;66(3):248-56.
2006: Chinnaiyan Prakash; Varambally Sooryanarayana; Tomlins Scott A; Ray Soma; Huang Shyhmin; Chinnaiyan Arul M; Harari Paul M
Enhancing the antitumor activity of ErbB blockade with histone deacetylase (HDAC) inhibition.
International journal of cancer. Journal international du cancer 2006;118(4):1041-50.
2006: Bismar Tarek A; Demichelis Francesca; Riva Alberto; Kim Robert; Varambally Sooryanarayana; He Le; Kutok Jeff; Aster Jonathan C; Tang Jeffery; Kuefer Rainer; Hofer Matthias D; Febbo Phillip G; Chinnaiyan Arul M; Rubin Mark A
Defining aggressive prostate cancer using a 12-gene model.
Neoplasia (New York, N.Y.) 2006;8(1):59-68.
2006: Masumoto Junya; Yang Kangkang; Varambally Sooryanarayana; Hasegawa Mizuho; Tomlins Scott A; Qiu Su; Fujimoto Yukari; Kawasaki Akiko; Foster Simon J; Horie Yasuo; Mak Tak W; Núñez Gabriel; Chinnaiyan Arul M; Fukase Koichi; Inohara Naohiro
Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo.
The Journal of experimental medicine 2006;203(1):203-13.
2006: Finn William G; Sreekumar Arun; Menon Anjana; Utiger Cheryl; Chinnaiyan Arul
Trisomy 12-associated, t(11;14)-negative mature B-cell leukemia with gene expression profile resembling mantle cell lymphoma.
Leukemia & lymphoma 2006;47(1):121-7.
2006: Tomlins Scott A; Rubin Mark A; Chinnaiyan Arul M
Integrative biology of prostate cancer progression.
Annual review of pathology 2006;1():243-71.
2006: Molinaro Ross J; Jha Babal Kant; Malathi Krishnamurthy; Varambally Sooryanarayana; Chinnaiyan Arul M; Silverman Robert H
Selection and cloning of poly(rC)-binding protein 2 and Raf kinase inhibitor protein RNA activators of 2',5'-oligoadenylate synthetase from prostate cancer cells.
Nucleic acids research 2006;34(22):6684-95.
2006: Creighton Chad J; Cordero Kevin E; Larios Jose M; Miller Rebecca S; Johnson Michael D; Chinnaiyan Arul M; Lippman Marc E; Rae James M
Genes regulated by estrogen in breast tumor cells in vitro are similarly regulated in vivo in tumor xenografts and human breast tumors.
Genome biology 2006;7(4):R28.
2005: Mehra Rohit; Varambally Sooryanarayana; Ding Lei; Shen Ronglai; Sabel Michael S; Ghosh Debashis; Chinnaiyan Arul M; Kleer Celina G
Identification of GATA3 as a breast cancer prognostic marker by global gene expression meta-analysis.
Cancer research 2005;65(24):11259-64.
2005: Kunju L P; Chinnaiyan A M; Shah R B
Comparison of monoclonal antibody (P504S) and polyclonal antibody to alpha methylacyl-CoA racemase (AMACR) in the work-up of prostate cancer.
Histopathology 2005;47(6):587-96.
2005: Zeidler Michael; Varambally Sooryanarayana; Cao Qi; Chinnaiyan Arul M; Ferguson David O; Merajver Sofia D; Kleer Celina G
The Polycomb group protein EZH2 impairs DNA repair in breast epithelial cells.
Neoplasia (New York, N.Y.) 2005;7(11):1011-9.
2005: Varambally Sooryanarayana; Yu Jianjun; Laxman Bharathi; Rhodes Daniel R; Mehra Rohit; Tomlins Scott A; Shah Rajal B; Chandran Uma; Monzon Federico A; Becich Michael J; Wei John T; Pienta Kenneth J; Ghosh Debashis; Rubin Mark A; Chinnaiyan Arul M
Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression.
Cancer cell 2005;8(5):393-406.
2005: Olle Eric W; Sreekumar Arun; Warner Roscoe L; McClintock Shannon D; Chinnaiyan Arul M; Bleavins Michael R; Anderson Timothy D; Johnson Kent J
Development of an internally controlled antibody microarray.
Molecular & cellular proteomics : MCP 2005;4(11):1664-72.
2005: Tomlins Scott A; Rhodes Daniel R; Perner Sven; Dhanasekaran Saravana M; Mehra Rohit; Sun Xiao-Wei; Varambally Sooryanarayana; Cao Xuhong; Tchinda Joelle; Kuefer Rainer; Lee Charles; Montie James E; Shah Rajal B; Pienta Kenneth J; Rubin Mark A; Chinnaiyan Arul M
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.
Science (New York, N.Y.) 2005;310(5748):644-8.
2005: Wang Xiaoju; Yu Jianjun; Sreekumar Arun; Varambally Sooryanarayana; Shen Ronglai; Giacherio Donald; Mehra Rohit; Montie James E; Pienta Kenneth J; Sanda Martin G; Kantoff Philip W; Rubin Mark A; Wei John T; Ghosh Debashis; Chinnaiyan Arul M
Autoantibody signatures in prostate cancer.
The New England journal of medicine 2005;353(12):1224-35.
2005: Rhodes Daniel R; Tomlins Scott A; Varambally Sooryanarayana; Mahavisno Vasudeva; Barrette Terrence; Kalyana-Sundaram Shanker; Ghosh Debashis; Pandey Akhilesh; Chinnaiyan Arul M
Probabilistic model of the human protein-protein interaction network.
Nature biotechnology 2005;23(8):951-9.
2005: Ghosh Debashis; Chinnaiyan Arul M
Classification and selection of biomarkers in genomic data using LASSO.
Journal of biomedicine & biotechnology 2005;2005(2):147-54.
2005: Rubin Mark A; Bismar Tarek A; Andrén Ove; Mucci Lorelei; Kim Robert; Shen Ronglai; Ghosh Debashis; Wei John T; Chinnaiyan Arul M; Adami Hans-Olov; Kantoff Philip W; Johansson Jan-Erik
Decreased alpha-methylacyl CoA racemase expression in localized prostate cancer is associated with an increased rate of biochemical recurrence and cancer-specific death.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(6):1424-32.
2005: Witkiewicz Agnieszka K; Varambally Sooryanarayana; Shen Ronglai; Mehra Rohit; Sabel Michael S; Ghosh Debashis; Chinnaiyan Arul M; Rubin Mark A; Kleer Celina G
Alpha-methylacyl-CoA racemase protein expression is associated with the degree of differentiation in breast cancer using quantitative image analysis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(6):1418-23.
2005: Rhodes Daniel R; Chinnaiyan Arul M
Integrative analysis of the cancer transcriptome.
Nature genetics 2005;37 Suppl():S31-7.
2005: Rhodes Daniel R; Kalyana-Sundaram Shanker; Mahavisno Vasudeva; Barrette Terrence R; Ghosh Debashis; Chinnaiyan Arul M
Mining for regulatory programs in the cancer transcriptome.
Nature genetics 2005;37(6):579-83.
2005: Thomas Monzy; Yu Zhigang; Dadgar Nahid; Varambally Sooryanarayana; Yu Jianjun; Chinnaiyan Arul M; Lieberman Andrew P
The unfolded protein response modulates toxicity of the expanded glutamine androgen receptor.
The Journal of biological chemistry 2005;280(22):21264-71.
2005: Bradley Sarah V; Oravecz-Wilson Katherine I; Bougeard Gaelle; Mizukami Ikuko; Li Lina; Munaco Anthony J; Sreekumar Arun; Corradetti Michael N; Chinnaiyan Arul M; Sanda Martin G; Ross Theodora S
Serum antibodies to huntingtin interacting protein-1: a new blood test for prostate cancer.
Cancer research 2005;65(10):4126-33.
2005: Chinnaiyan Prakash; Huang Shyhmin; Vallabhaneni Geetha; Armstrong Eric; Varambally Sooryanarayana; Tomlins Scott A; Chinnaiyan Arul M; Harari Paul M
Mechanisms of enhanced radiation response following epidermal growth factor receptor signaling inhibition by erlotinib (Tarceva).
Cancer research 2005;65(8):3328-35.
2005: Lippman Marc E; Benz Chris; Chinnaiyan Arul; Flockhart David; Harris Adrian; Hudis Clifford; Osborne C Kent; Press Michael F; Rae James; Sledge George W; Van't Veer Laura; Wicha Max
Consensus statement: Expedition Inspiration 2004 Breast Cancer Symposium 'Breast Cancer--The Development and Validation of New Therapeutics'.
Breast cancer research and treatment 2005;90(1):1-3.
2005: Narla Goutham; Difeo Analisa; Reeves Helen L; Schaid Daniel J; Hirshfeld Jennifer; Hod Eldad; Katz Amanda; Isaacs William B; Hebbring Scott; Komiya Akira; McDonnell Shannon K; Wiley Kathleen E; Jacobsen Steven J; Isaacs Sarah D; Walsh Patrick C; Zheng S Lilly; Chang Bao-Li; Friedrichsen Danielle M; Stanford Janet L; Ostrander Elaine A; Chinnaiyan Arul M; Rubin Mark A; Xu Jianfeng; Thibodeau Stephen N; Friedman Scott L; Martignetti John A
A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk.
Cancer research 2005;65(4):1213-22.
2005: Dhanasekaran Saravana Mohan; Dash Atreya; Yu Jianjun; Maine Ira P; Laxman Bharathi; Tomlins Scott A; Creighton Chad J; Menon Anjana; Rubin Mark A; Chinnaiyan Arul M
Molecular profiling of human prostate tissues: insights into gene expression patterns of prostate development during puberty.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(2):243-5.
2005: Ghosh Debashis; Chinnaiyan Arul M
Covariate adjustment in the analysis of microarray data from clinical studies.
Functional & integrative genomics 2005;5(1):18-27.
2005: Kim Robert; Demichelis Francesca; Tang Jeffery; Riva Alberto; Shen Ronglai; Gibbs Doug F; Mahavishno Vasudeva; Chinnaiyan Arul M; Rubin Mark A
Internet-based Profiler system as integrative framework to support translational research.
BMC bioinformatics 2005;6():304.
2004: Shah Rajal B; Mehra Rohit; Chinnaiyan Arul M; Shen Ronglai; Ghosh Debashis; Zhou Ming; Macvicar Gary R; Varambally Soorynarayana; Harwood Jason; Bismar Tarek A; Kim Robert; Rubin Mark A; Pienta Kenneth J
Androgen-independent prostate cancer is a heterogeneous group of diseases: lessons from a rapid autopsy program.
Cancer research 2004;64(24):9209-16.
2004: Santagata Sandro; Demichelis Francesca; Riva Alberto; Varambally Sooryanarayana; Hofer Matthias D; Kutok Jeffery L; Kim Robert; Tang Jeffery; Montie James E; Chinnaiyan Arul M; Rubin Mark A; Aster Jon C
JAGGED1 expression is associated with prostate cancer metastasis and recurrence.
Cancer research 2004;64(19):6854-7.
2004: Hofer Matthias D; Fecko Alice; Shen Ronglai; Setlur Sunita R; Pienta Kenneth G; Tomlins Scott A; Chinnaiyan Arul M; Rubin Mark A
Expression of the platelet-derived growth factor receptor in prostate cancer and treatment implications with tyrosine kinase inhibitors.
Neoplasia (New York, N.Y.) 2004;6(5):503-12.
2004: Paris Pamela L; Andaya Armann; Fridlyand Jane; Jain Ajay N; Weinberg Vivian; Kowbel David; Brebner John H; Simko Jeff; Watson J E Vivienne; Volik Stas; Albertson Donna G; Pinkel Daniel; Alers Janneke C; van der Kwast Theodorus H; Vissers Kees J; Schroder Fritz H; Wildhagen Mark F; Febbo Phillip G; Chinnaiyan Arul M; Pienta Kenneth J; Carroll Peter R; Rubin Mark A; Collins Colin; van Dekken Herman
Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumors.
Human molecular genetics 2004;13(13):1303-13.
2004: Rhodes Daniel R; Yu Jianjun; Shanker K; Deshpande Nandan; Varambally Radhika; Ghosh Debashis; Barrette Terrence; Pandey Akhilesh; Chinnaiyan Arul M
Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(25):9309-14.
2004: Sreekumar Arun; Laxman Bharathi; Rhodes Daniel R; Bhagavathula Srilakshmi; Harwood Jason; Giacherio Donald; Ghosh Debashis; Sanda Martin G; Rubin Mark A; Chinnaiyan Arul M
Humoral immune response to alpha-methylacyl-CoA racemase and prostate cancer.
Journal of the National Cancer Institute 2004;96(11):834-43.
2004: Rubin Mark A; Varambally Sooryanarayana; Beroukhim Rameen; Tomlins Scott A; Rhodes Daniel R; Paris Pamela L; Hofer Matthias D; Storz-Schweizer Martina; Kuefer Rainer; Fletcher Jonathan A; Hsi Bae-Li; Byrne Jennifier A; Pienta Kenneth J; Collins Colin; Sellers William R; Chinnaiyan Arul M
Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer.
Cancer research 2004;64(11):3814-22.
2004: Rhodes Daniel R; Chinnaiyan Arul M
Bioinformatics strategies for translating genome-wide expression analyses into clinically useful cancer markers.
Annals of the New York Academy of Sciences 2004;1020():32-40.
2004: Liu Tianju; Dhanasekaran Saravana M; Jin Hong; Hu Biao; Tomlins Scott A; Chinnaiyan Arul M; Phan Sem H
FIZZ1 stimulation of myofibroblast differentiation.
The American journal of pathology 2004;164(4):1315-26.
2004: Watson J E Vivienne; Doggett Norman A; Albertson Donna G; Andaya Armann; Chinnaiyan Arul; van Dekken Herman; Ginzinger David; Haqq Christopher; James Karen; Kamkar Sherwin; Kowbel David; Pinkel Daniel; Schmitt Lars; Simko Jeffry P; Volik Stanislav; Weinberg Vivian K; Paris Pamela L; Collins Colin
Integration of high-resolution array comparative genomic hybridization analysis of chromosome 16q with expression array data refines common regions of loss at 16q23-qter and identifies underlying candidate tumor suppressor genes in prostate cancer.
Oncogene 2004;23(19):3487-94.
2004: Wu Mei; Wu Zhi-Fen; Kumar-Sinha Chandan; Chinnaiyan Arul; Merajver Sofia D
RhoC induces differential expression of genes involved in invasion and metastasis in MCF10A breast cells.
Breast cancer research and treatment 2004;84(1):3-12.
2004: Albrecht Eric A; Chinnaiyan Arul M; Varambally Sooryanarayana; Kumar-Sinha Chandan; Barrette Terrence R; Sarma J Vidya; Ward Peter A
C5a-induced gene expression in human umbilical vein endothelial cells.
The American journal of pathology 2004;164(3):849-59.
2004: Rubin Mark A; Zerkowski Maciej P; Camp Robert L; Kuefer Rainer; Hofer Matthias D; Chinnaiyan Arul M; Rimm David L
Quantitative determination of expression of the prostate cancer protein alpha-methylacyl-CoA racemase using automated quantitative analysis (AQUA): a novel paradigm for automated and continuous biomarker measurements.
The American journal of pathology 2004;164(3):831-40.
2004: Kumar-Sinha Chandan; Shah Rajal B; Laxman Bharathi; Tomlins Scott A; Harwood Jason; Schmitz Werner; Conzelmann Ernst; Sanda Martin G; Wei John T; Rubin Mark A; Chinnaiyan Arul M
Elevated alpha-methylacyl-CoA racemase enzymatic activity in prostate cancer.
The American journal of pathology 2004;164(3):787-93.
2004: Hofer Matthias D; Kuefer Rainer; Varambally Sooryanarayana; Li Haojie; Ma Jing; Shapiro Geoffrey I; Gschwend Juergen E; Hautmann Richard E; Sanda Martin G; Giehl Klaudia; Menke Andre; Chinnaiyan Arul M; Rubin Mark A
The role of metastasis-associated protein 1 in prostate cancer progression.
Cancer research 2004;64(3):825-9.
2004: Rhodes Daniel R; Yu Jianjun; Shanker K; Deshpande Nandan; Varambally Radhika; Ghosh Debashis; Barrette Terrence; Pandey Akhilesh; Chinnaiyan Arul M
ONCOMINE: a cancer microarray database and integrated data-mining platform.
Neoplasia (New York, N.Y.) 2004;6(1):1-6.
2004: Nyati Mukesh K; Maheshwari Divya; Hanasoge Sheela; Sreekumar Arun; Rynkiewicz Susan D; Chinnaiyan Arul M; Leopold Wilbur R; Ethier Stephen P; Lawrence Theodore S
Radiosensitization by pan ErbB inhibitor CI-1033 in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(2):691-700.
2004: Knight Paul R; Sreekumar Arun; Siddiqui Javed; Laxman Bharathi; Copeland Shannon; Chinnaiyan Arul; Remick Daniel G
Development of a sensitive microarray immunoassay and comparison with standard enzyme-linked immunoassay for cytokine analysis.
Shock (Augusta, Ga.) 2004;21(1):26-30.
2004: Shen Ronglai; Ghosh Debashis; Chinnaiyan Arul M
Prognostic meta-signature of breast cancer developed by two-stage mixture modeling of microarray data.
BMC genomics 2004;5(1):94.
2003: Kumar-Sinha Chandan; Chinnaiyan Arul M
Molecular markers to identify patients at risk for recurrence after primary treatment for prostate cancer.
Urology 2003;62 Suppl 1():19-35.
2003: Kuefer Rainer; Hofer Matthias D; Gschwend Juergen E; Pienta Kenneth J; Sanda Martin G; Chinnaiyan Arul M; Rubin Mark A; Day Mark L
The role of an 80 kDa fragment of E-cadherin in the metastatic progression of prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(17):6447-52.
2003: Ghosh Debashis; Barette Terrence R; Rhodes Dan; Chinnaiyan Arul M
Statistical issues and methods for meta-analysis of microarray data: a case study in prostate cancer.
Functional & integrative genomics 2003;3(4):180-8.
2003: Kunju Lakshmi P; Rubin Mark A; Chinnaiyan Arul M; Shah Rajal B
Diagnostic usefulness of monoclonal antibody P504S in the workup of atypical prostatic glandular proliferations.
American journal of clinical pathology 2003;120(5):737-45.
2003: Peri Suraj; Navarro J Daniel; Amanchy Ramars; Kristiansen Troels Z; Jonnalagadda Chandra Kiran; Surendranath Vineeth; Niranjan Vidya; Muthusamy Babylakshmi; Gandhi T K B; Gronborg Mads; Ibarrola Nieves; Deshpande Nandan; Shanker K; Shivashankar H N; Rashmi B P; Ramya M A; Zhao Zhixing; Chandrika K N; Padma N; Harsha H C; Yatish A J; Kavitha M P; Menezes Minal; Choudhury Dipanwita Roy; Suresh Shubha; Ghosh Neelanjana; Saravana R; Chandran Sreenath; Krishna Subhalakshmi; Joy Mary; Anand Sanjeev K; Madavan V; Joseph Ansamma; Wong Guang W; Schiemann William P; Constantinescu Stefan N; Huang Lily; Khosravi-Far Roya; Steen Hanno; Tewari Muneesh; Ghaffari Saghi; Blobe Gerard C; Dang Chi V; Garcia Joe G N; Pevsner Jonathan; Jensen Ole N; Roepstorff Peter; Deshpande Krishna S; Chinnaiyan Arul M; Hamosh Ada; Chakravarti Aravinda; Pandey Akhilesh
Development of human protein reference database as an initial platform for approaching systems biology in humans.
Genome research 2003;13(10):2363-71.
2003: Kleer Celina G; Cao Qi; Varambally Sooryanarayana; Shen Ronglai; Ota Ichiro; Tomlins Scott A; Ghosh Debashis; Sewalt Richard G A B; Otte Arie P; Hayes Daniel F; Sabel Michael S; Livant Donna; Weiss Stephen J; Rubin Mark A; Chinnaiyan Arul M
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11606-11.
2003: Kumar-Sinha Chandan; Rhodes Daniel R; Yu Jianjun; Chinnaiyan Arul M
Prostate cancer biomarkers: a current perspective.
Expert review of molecular diagnostics 2003;3(4):459-70.
2003: Yan Fang; Sreekumar Arun; Laxman Bharathi; Chinnaiyan Arul M; Lubman David M; Barder Timothy J
Protein microarrays using liquid phase fractionation of cell lysates.
Proteomics 2003;3(7):1228-35.
2003: Sun Yan-Xi; Wang Jingcheng; Shelburne Charles E; Lopatin Dennis E; Chinnaiyan Arul M; Rubin Mark A; Pienta Kenneth J; Taichman Russell S
Expression of CXCR4 and CXCL12 (SDF-1) in human prostate cancers (PCa) in vivo.
Journal of cellular biochemistry 2003;89(3):462-73.
2003: Rhodes Daniel R; Sanda Martin G; Otte Arie P; Chinnaiyan Arul M; Rubin Mark A
Multiplex biomarker approach for determining risk of prostate-specific antigen-defined recurrence of prostate cancer.
Journal of the National Cancer Institute 2003;95(9):661-8.
2003: Kumar-Sinha Chandan; Ignatoski Kathleen Woods; Lippman Marc E; Ethier Stephen P; Chinnaiyan Arul M
Transcriptome analysis of HER2 reveals a molecular connection to fatty acid synthesis.
Cancer research 2003;63(1):132-9.
2003: Xin Wei; Rhodes Daniel R; Ingold Collette; Chinnaiyan Arul M; Rubin Mark A
Dysregulation of the annexin family protein family is associated with prostate cancer progression.
The American journal of pathology 2003;162(1):255-61.
2003: Rios-Doria Jonathan; Day Kathleen C; Kuefer Rainer; Rashid Michael G; Chinnaiyan Arul M; Rubin Mark A; Day Mark L
The role of calpain in the proteolytic cleavage of E-cadherin in prostate and mammary epithelial cells.
The Journal of biological chemistry 2003;278(2):1372-9.
2002: Sreekumar Arun; Chinnaiyan Arul M
Protein microarrays: a powerful tool to study cancer.
Current opinion in molecular therapeutics 2002;4(6):587-93.
2002: Sreekumar Arun; Chinnaiyan Arul M
Using protein microarrays to study cancer.
BioTechniques 2002;Suppl():46-53.
2002: Chay Christopher H; Cooper Carlton R; Gendernalik James D; Dhanasekaran Saravana M; Chinnaiyan Arul M; Rubin Mark A; Schmaier Alvin H; Pienta Kenneth J
A functional thrombin receptor (PAR1) is expressed on bone-derived prostate cancer cell lines.
Urology 2002;60(5):760-5.
2002: Dash Atreya; Maine Ira P; Varambally Sooryanarayana; Shen Ronglai; Chinnaiyan Arul M; Rubin Mark A
Changes in differential gene expression because of warm ischemia time of radical prostatectomy specimens.
The American journal of pathology 2002;161(5):1743-8.
2002: Varambally Sooryanarayana; Dhanasekaran Saravana M; Zhou Ming; Barrette Terrence R; Kumar-Sinha Chandan; Sanda Martin G; Ghosh Debashis; Pienta Kenneth J; Sewalt Richard G A B; Otte Arie P; Rubin Mark A; Chinnaiyan Arul M
The polycomb group protein EZH2 is involved in progression of prostate cancer.
Nature 2002;419(6907):624-9.
2002: Rhodes Daniel R; Chinnaiyan Arul M
DNA microarrays: implications for clinical medicine.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 2002;15(5):275-9.
2002: Kuefer Rainer; Varambally Sooryanarayana; Zhou Ming; Lucas Peter C; Loeffler Martin; Wolter Hubertus; Mattfeldt Torsten; Hautmann Richard E; Gschwend Juergen E; Barrette Terrence R; Dunn Rodney L; Chinnaiyan Arul M; Rubin Mark A
alpha-Methylacyl-CoA racemase: expression levels of this novel cancer biomarker depend on tumor differentiation.
The American journal of pathology 2002;161(3):841-8.
2002: Rhodes Daniel R; Barrette Terrence R; Rubin Mark A; Ghosh Debashis; Chinnaiyan Arul M
Meta-analysis of microarrays: interstudy validation of gene expression profiles reveals pathway dysregulation in prostate cancer.
Cancer research 2002;62(15):4427-33.
2002: Zhou Ming; Chinnaiyan Arul M; Kleer Celina G; Lucas Peter C; Rubin Mark A
Alpha-Methylacyl-CoA racemase: a novel tumor marker over-expressed in several human cancers and their precursor lesions.
The American journal of surgical pathology 2002;26(7):926-31.
2002: Nyati Mukesh K; Sreekumar Arun; Li Shengping; Zhang Ming; Rynkiewicz Susan D; Chinnaiyan Arul M; Rehemtulla Alnawaz; Lawrence Theodore S
High and selective expression of yeast cytosine deaminase under a carcinoembryonic antigen promoter-enhancer.
Cancer research 2002;62(8):2337-42.
2002: Rubin Mark A; Zhou Ming; Dhanasekaran Saravana M; Varambally Sooryanarayana; Barrette Terrence R; Sanda Martin G; Pienta Kenneth J; Ghosh Debashis; Chinnaiyan Arul M
alpha-Methylacyl coenzyme A racemase as a tissue biomarker for prostate cancer.
JAMA : the journal of the American Medical Association 2002;287(13):1662-70.
2002: Ghosh Debashis; Chinnaiyan Arul M
Mixture modelling of gene expression data from microarray experiments.
Bioinformatics (Oxford, England) 2002;18(2):275-86.
2002: Chinnaiyan Arul M; Rubin Mark A
Gene-expression profiles in hereditary breast cancer.
Advances in anatomic pathology 2002;9(1):1-6.
2002: Kumar-Sinha Chandan; Varambally Sooryanarayana; Sreekumar Arun; Chinnaiyan Arul M
Molecular cross-talk between the TRAIL and interferon signaling pathways.
The Journal of biological chemistry 2002;277(1):575-85.
2001: Sreekumar A; Nyati M K; Varambally S; Barrette T R; Ghosh D; Lawrence T S; Chinnaiyan A M
Profiling of cancer cells using protein microarrays: discovery of novel radiation-regulated proteins.
Cancer research 2001;61(20):7585-93.
2001: Chinnaiyan A M; Huber-Lang M; Kumar-Sinha C; Barrette T R; Shankar-Sinha S; Sarma V J; Padgaonkar V A; Ward P A
Molecular signatures of sepsis: multiorgan gene expression profiles of systemic inflammation.
The American journal of pathology 2001;159(4):1199-209.
2001: Dhanasekaran S M; Barrette T R; Ghosh D; Shah R; Varambally S; Kurachi K; Pienta K J; Rubin M A; Chinnaiyan A M
Delineation of prognostic biomarkers in prostate cancer.
Nature 2001;412(6849):822-6.
2000: Chinnaiyan A M; Prasad U; Shankar S; Hamstra D A; Shanaiah M; Chenevert T L; Ross B D; Rehemtulla A
Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(4):1754-9.
1999: Rehemtulla A; Hamilton A C; Taneja N; Fridman J; Juan T S; Maybaum J; Chinnaiyan A
A caspase-resistant form of Bcl-X(L), but not wild type Bcl-X(L), promotes clonogenic survival after ionizing radiation.
Neoplasia (New York, N.Y.) 1999;1(1):63-70.
1999: Chinnaiyan A M
The apoptosome: heart and soul of the cell death machine.
Neoplasia (New York, N.Y.) 1999;1(1):5-15.
1998: Chaudhary D; O'Rourke K; Chinnaiyan A M; Dixit V M
The death inhibitory molecules CED-9 and CED-4L use a common mechanism to inhibit the CED-3 death protease.
The Journal of biological chemistry 1998;273(28):17708-12.
1998: Walsh C M; Wen B G; Chinnaiyan A M; O'Rourke K; Dixit V M; Hedrick S M
A role for FADD in T cell activation and development.
Immunity 1998;8(4):439-49.
1997: Rehemtulla A; Hamilton C A; Chinnaiyan A M; Dixit V M
Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1).
The Journal of biological chemistry 1997;272(41):25783-6.
1997: Fraser A; Chinnaiyan A M
Keystone 1997: return of the worm. Temarron, Colorado, February 18-23, 1997.
Cell death and differentiation 1997;4(6):519-21.
1997: Chinnaiyan A M; Chaudhary D; O'Rourke K; Koonin E V; Dixit V M
Role of CED-4 in the activation of CED-3.
Nature 1997;388(6644):728-9.
1997: Pan G; O'Rourke K; Chinnaiyan A M; Gentz R; Ebner R; Ni J; Dixit V M
The receptor for the cytotoxic ligand TRAIL.
Science (New York, N.Y.) 1997;276(5309):111-3.
1997: Chinnaiyan A M; Woffendin C; Dixit V M; Nabel G J
The inhibition of pro-apoptotic ICE-like proteases enhances HIV replication.
Nature medicine 1997;3(3):333-7.
1997: Chinnaiyan A M; Dixit V M
Portrait of an executioner: the molecular mechanism of FAS/APO-1-induced apoptosis.
Seminars in immunology 1997;9(1):69-76.
1997: Chinnaiyan A M; O'Rourke K; Lane B R; Dixit V M
Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death.
Science (New York, N.Y.) 1997;275(5303):1122-6.
1996: Cahill M A; Peter M E; Kischkel F C; Chinnaiyan A M; Dixit V M; Krammer P H; Nordheim A
CD95 (APO-1/Fas) induces activation of SAP kinases downstream of ICE-like proteases.
Oncogene 1996;13(10):2087-96.
1996: Chinnaiyan A M; O'Rourke K; Yu G L; Lyons R H; Garg M; Duan D R; Xing L; Gentz R; Ni J; Dixit V M
Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95.
Science (New York, N.Y.) 1996;274(5289):990-2.
1996: Chinnaiyan A M; Hanna W L; Orth K; Duan H; Poirier G G; Froelich C J; Dixit V M
Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3.
Current biology : CB 1996;6(7):897-9.
1996: Orth K; Chinnaiyan A M; Garg M; Froelich C J; Dixit V M
The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A.
The Journal of biological chemistry 1996;271(28):16443-6.
1996: Duan H; Orth K; Chinnaiyan A M; Poirier G G; Froelich C J; He W W; Dixit V M
ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B.
The Journal of biological chemistry 1996;271(28):16720-4.
1996: Muzio M; Chinnaiyan A M; Kischkel F C; O'Rourke K; Shevchenko A; Ni J; Scaffidi C; Bretz J D; Zhang M; Gentz R; Mann M; Krammer P H; Peter M E; Dixit V M
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.
Cell 1996;85(6):817-27.
1996: Chinnaiyan A M; Dixit V M
The cell-death machine.
Current biology : CB 1996;6(5):555-62.
1996: Peter M E; Kischkel F C; Hellbardt S; Chinnaiyan A M; Krammer P H; Dixit V M
CD95 (APO-1/Fas)-associating signalling proteins.
Cell death and differentiation 1996;3(2):161-70.
1996: Chinnaiyan A M; Tepper C G; Seldin M F; O'Rourke K; Kischkel F C; Hellbardt S; Krammer P H; Peter M E; Dixit V M
FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis.
The Journal of biological chemistry 1996;271(9):4961-5.
1996: Chinnaiyan A M; Orth K; O'Rourke K; Duan H; Poirier G G; Dixit V M
Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases.
The Journal of biological chemistry 1996;271(9):4573-6.
1996: Duan H; Chinnaiyan A M; Hudson P L; Wing J P; He W W; Dixit V M
ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis.
The Journal of biological chemistry 1996;271(3):1621-5.
1995: Chinnaiyan A M; O'Rourke K; Tewari M; Dixit V M
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.
Cell 1995;81(4):505-12.
1993: Mulligan M S; Desrochers P E; Chinnaiyan A M; Gibbs D F; Varani J; Johnson K J; Weiss S J
In vivo suppression of immune complex-induced alveolitis by secretory leukoproteinase inhibitor and tissue inhibitor of metalloproteinases 2.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(24):11523-7.

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