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Antonio Chiocca

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Kenneth K Tanabe; E Antonio Chiocca
"Infectious" optimism for treatment of hepatocellular carcinoma.
Laura B Ngwenya; E Antonio Chiocca
Editorial: postoperative ischemia.
Ammar Shaikhouni; E Antonio Chiocca
Editorial: glioblastoma and surgery.

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All Publications

2013: Kenneth K Tanabe; E Antonio Chiocca
"Infectious" optimism for treatment of hepatocellular carcinoma.
Molecular therapy : the journal of the American Society of Gene Therapy 2013;21(4):722-4.
2013: Laura B Ngwenya; E Antonio Chiocca
Editorial: postoperative ischemia.
Journal of neurosurgery 2013;118(4):799-800; discussion 800.
2013: Ammar Shaikhouni; E Antonio Chiocca
Editorial: glioblastoma and surgery.
Journal of neurosurgery 2013;118(4):809-11; discussion 810-1.
2013: Manabu Onishi; Koichi Yoshida; E Antonio Chiocca; Kentaro Fujii; Tomotsugu Ichikawa; Satoshi Inoue; Balveen Kaur; Kazuhiko Kurozumi; Hiroyuki Michiue; Isao Date
Bimodal anti-glioma mechanisms of cilengitide demonstrated by novel invasive glioma models.
Neuropathology : official journal of the Japanese Society of Neuropathology 2013;33(2):162-74.
2013: Hiroaki Uchida; Ji Young Yoo; Hyunjung Baek; Janet Chan; E Antonio Chiocca; Justus B Cohen; William F Goins; Paola Grandi; Amy Haseley; Chang-Sook Hong; Balveen Kaur; Izumi Kumagai; Masahide Kuroki; Heechung Kwon; Marco Marzulli; Lucia Mazzacurati; Kenji Nakano; Hiroshi Nakashima; Joseph C Glorioso
Effective treatment of an orthotopic xenograft model of human glioblastoma using an EGFR-retargeted oncolytic herpes simplex virus.
Molecular therapy : the journal of the American Society of Gene Therapy 2013;21(3):561-9.
2013: Laura B Ngwenya; E Antonio Chiocca
Do meningioma patients benefit from antiepileptic drug treatment?
World neurosurgery 2013;79(3-4):433-4.
2013: J Bradley Elder; E Antonio Chiocca
Molecular and genetic characterization of meningiomas: future predictive assays and "personalized" treatment.
World neurosurgery 2013;79(2):247-8.
2012: Christopher A Alvarez-Breckenridge; Michael A Caligiuri; Soledad A Fernandez; Jayson Hardcastle; Shun He; Balveen Kaur; Sean E Lawler; Ofer Mandelboim; Hsiaoyin Mao; Alessandro Moretta; Jason Pradarelli; Richard Price; Eric Vivier; Yan Wang; Min Wei; Jeffrey Wojton; Jianhua Yu; E Antonio Chiocca
NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors.
Nature medicine 2012;18(12):1827-34.
2012: Laura K Aguilar; Estuardo Aguilar-Cordova; Mariel Arvizu; E Antonio Chiocca
The spectrum of vaccine therapies for patients with glioblastoma multiforme.
Current treatment options in oncology 2012;13(4):437-50.
2012: Satoshi Inoue; Hirokazu Kambara; Kazuhiko Kurozumi; Tomoko Maruo; Manabu Onishi; Koichi Yoshida; E Antonio Chiocca; Kentaro Fujii; Tomotsugu Ichikawa; Isao Date
Novel animal glioma models that separately exhibit two different invasive and angiogenic phenotypes of human glioblastomas.
World neurosurgery 2012;78(6):670-82.
2012: Richard L Price; Katherine Bingmer; Charles Cook; Lualhati Harkins; O Hans Iwenofu; Chang-Hyuk Kwon; Christopher Pelloski; E Antonio Chiocca
Cytomegalovirus infection leads to pleomorphic rhabdomyosarcomas in Trp53+/- mice.
Cancer research 2012;72(22):5669-74.
2012: Andrew Shaw; E Antonio Chiocca
Von Hippel-Lindau disease and pregnancy.
Journal of neurosurgery 2012;117(5):815-6; discussion 816-7.
2012: NaTosha N Gatson; E Antonio Chiocca; Balveen Kaur
Anti-angiogenic gene therapy in the treatment of malignant gliomas.
Neuroscience letters 2012;527(2):62-70.
2012: J Bradley Elder; E Antonio Chiocca
Editorial: radiosurgery and atypical meningiomas.
Journal of neurosurgery 2012;117(4):676-8.
2012: Laura B Ngwenya; E Antonio Chiocca
Editorial: meningioma and radiotherapy.
Journal of neurosurgery 2012;117(4):666-8.
2012: Daniel Ikeda; E Antonio Chiocca
Editorial: dural tail sign.
Journal of neurosurgery 2012;117(4):643-4.
2012: Ji Young Yoo; Jun-Ge Yu; Christopher A Alvarez-Breckenridge; Anna Bratasz; E Antonio Chiocca; Joseph C Glorioso; Amy Haseley; Azeem Kaka; Andrew P Mazar; Matthew Old; Kimerly Powell; Jason Pradarelli; Theodoros N Teknos; Jeffrey Wojton; Balveen Kaur
Copper chelation enhances antitumor efficacy and systemic delivery of oncolytic HSV.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(18):4931-41.
2012: Andrew Shaw; E Antonio Chiocca
Editorial: functional neurooncology.
Journal of neurosurgery 2012;117(3):463-4; discussion 464-5.
2012: Paul Porensky; E Antonio Chiocca
Stage IV melanoma.
Journal of neurosurgery 2012;117(2):225-6; discussion 226.
2012: J Bradley Elder; E Antonio Chiocca
Convection-enhanced delivery.
Journal of neurosurgery 2012;117(2):193-5; discussion 195-6.
2012: Balveen Kaur; E Antonio Chiocca; Timothy P Cripe
Oncolytic HSV-1 virotherapy: clinical experience and opportunities for progress.
Current pharmaceutical biotechnology 2012;13(9):1842-51.
2012: Laura B Ngwenya; E Antonio Chiocca
Treatment for paragangliomas: passing the test of time.
World neurosurgery 2012;77(5-6):639-41.
2012: Ichiro Nakano; E Antonio Chiocca
Hope and challenges for dendritic cell-based vaccine therapy for glioblastoma.
World neurosurgery 2012;77(5-6):633-5.
2012: Christopher A Alvarez-Breckenridge; Stephen Bergin; Michael A Caligiuri; Soledad A Fernandez; Yoonhee P Ha; Christine Hwang; Balveen Kaur; Michal O Nowicki; Richard Price; Yan Wang; Min Wei; Jianhua Yu; E Antonio Chiocca
The histone deacetylase inhibitor valproic acid lessens NK cell action against oncolytic virus-infected glioblastoma cells by inhibition of STAT5/T-BET signaling and generation of gamma interferon.
Journal of virology 2012;86(8):4566-77.
2012: Daniel Ikeda; E Antonio Chiocca
Perioperative mortality.
Journal of neurosurgery 2012;116(4):821-2; discussion 822-4.
2012: Ciaran J Powers; E Antonio Chiocca
Editorial: urinary tract infection.
Journal of neurosurgery 2012;116(4):909; discussion 910.
2012: R Webster Crowley; Russell R Lonser; Robert M Starke; Edie E Zusman; Ashok R Asthagiri; E Antonio Chiocca
In-training factors predictive of choosing and sustaining a productive academic career path in neurological surgery.
Neurosurgery 2012;70(4):1024-32.
2012: Viren Patel; Gary Phillips; Cameron Rink; Sashwati Roy; Atom Sarkar; Bassel Shneker; E Antonio Chiocca; Elmahdi A Elkhammas; Michael S Firstenberg; Kasturi Ganesh; Urmila Gnyawali; Gayle M Gordillo; Savita Khanna; Robert Kirkpatrick; Emily Klatte; Michael Miller; J Layne More; Kalanithi Nesaretnam; Chandan K Sen
Oral tocotrienols are transported to human tissues and delay the progression of the model for end-stage liver disease score in patients.
The Journal of nutrition 2012;142(3):513-9.
2012: Agnieszka Bronisz; E Antonio Chiocca; S Cory; Soledad A Fernandez; Jakub Godlewski; M Hallett; R E Jimenez; S E Lawler; G Leone; F Li; C B Marsh; C K Martin; H Mathsyaraja; A S Merchant; Michal O Nowicki; Gerard J Nuovo; M Park; T Pécot; M G Piper; Thomas J Rosol; R Srinivasan; A J Trimboli; J A Wallace; Lisa D Yee; L Yu; Michael C Ostrowski
Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320.
Nature cell biology 2012;14(2):159-67.
2012: Ji Young Yoo; Jianying Zhang; Kimerly Powell; Anna Bratasz; E Antonio Chiocca; Amy Haseley; Balveen Kaur
Antitumor efficacy of 34.5ENVE: a transcriptionally retargeted and "Vstat120"-expressing oncolytic virus.
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(2):287-97.
2012: Pierpaolo Peruzzi; E Antonio Chiocca
Bringing the endovascular neurosurgeon into the neuro-oncology treatment team.
World neurosurgery 2012;77(1):59-61.
2012: Christopher A Alvarez-Breckenridge; Michael A Caligiuri; Balveen Kaur; Jianhua Yu; E Antonio Chiocca
Deciphering the Multifaceted Relationship between Oncolytic Viruses and Natural Killer Cells.
Advances in virology 2012;2012():702839.
2011: Mina Makary; Natali Erminy; Soledad Fernandez; Mahmoud Abdel-Rasoul; María Antor; Sergio D Bergese; E Antonio Chiocca; Roger Dzwonczyk
Clinical and economic outcomes of low-field intraoperative MRI-guided tumor resection neurosurgery.
Journal of magnetic resonance imaging : JMRI 2011;34(5):1022-30.
2011: Paul Porensky; E Antonio Chiocca
Use of 5-aminolevulinic acid for visualization of low-grade gliomas.
Journal of neurosurgery 2011;115(4):737-8; discussion 738-9.
2011: Andrew Shaw; E Antonio Chiocca
Neoplastic meningitis.
Journal of neurosurgery 2011;115(4):728-9; discussion 729.
2011: E Antonio Chiocca; John Grecula; Robert G Grossman; Jayson Hardcastle; Kimbra S Harris; Balveen Kaur; Simon Lo; Andrea G Manzanera; John McGregor; Carissa Monterroso; Laura K Aguilar; Estuardo Aguilar-Cordova; David S Baskin; Susan D Bell; Robert Cavaliere; Arnab Chakravarti; Herbert Newton; Abhik Ray-Chaudhuri; Todd W Trask; Pamela Z New
Phase IB study of gene-mediated cytotoxic immunotherapy adjuvant to up-front surgery and intensive timing radiation for malignant glioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(27):3611-9.
2011: Ciaran J Powers; E Antonio Chiocca
Stroke and heart disease: the "also-rans" of radiation exposure.
World neurosurgery 2011;76(3-4):216.
2011: Jenna Kahn; Jay Steven Loeffler; Andrzej Niemierko; Tracy Batchelor; E Antonio Chiocca; Arnab Chakravarti
Long-term outcomes of patients with spinal cord gliomas treated by modern conformal radiation techniques.
International journal of radiation oncology, biology, physics 2011;81(1):232-8.
2011: Shanté P Williams; Fang Liu; Michal O Nowicki; Rachael Press; Mahmoud Abdel-Rasoul; E Antonio Chiocca; Soledad A Fernandez; Jakub Godlewski; Balveen Kaur; Sean E Lawler
Indirubins decrease glioma invasion by blocking migratory phenotypes in both the tumor and stromal endothelial cell compartments.
Cancer research 2011;71(16):5374-80.
2011: Pierpaolo Peruzzi; E Antonio Chiocca
Prognosis and treatment of melanoma metastases to the central nervous system: lots of retrospective data, very few certainties.
World neurosurgery 2011;76(1-2):48-50.
2011: Christopher Alvarez-Breckenridge; E Antonio Chiocca
A viral strategy to ambush tumors.
Nature medicine 2011;17(7):784-5.
2011: Daniel Ikeda; E Antonio Chiocca
Measuring versus seeing.
Journal of neurosurgery 2011;115(1):9-10; discussion 10.
2011: Laura B Ngwenya; E Antonio Chiocca
Extent of resection.
Journal of neurosurgery 2011;115(1):1-2; discussion 2.
2011: Nina Dmitrieva; Lianbo Yu; Mariano Viapiano; Timothy P Cripe; E Antonio Chiocca; Joseph C Glorioso; Balveen Kaur
Chondroitinase ABC I-mediated enhancement of oncolytic virus spread and antitumor efficacy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(6):1362-72.
2011: Ichiro Nakano; E Antonio Chiocca
Finding drugs against CD133+ glioma subpopulations.
Journal of neurosurgery 2011;114(3):648; discussion 648-50.
2011: Atom Sarkar; E Antonio Chiocca
Multiple craniotomies.
Journal of neurosurgery 2011;114(3):574-5; discussion 575.
2011: James B Elder; E Antonio Chiocca
Meningioma surgery.
Journal of neurosurgery 2011;114(3):695; discussion 696.
2011: Pierpaolo Peruzzi; Sergio D Bergese; Adolfo Viloria; Erika G Puente; Mahmoud Abdel-Rasoul; E Antonio Chiocca
A retrospective cohort-matched comparison of conscious sedation versus general anesthesia for supratentorial glioma resection. Clinical article.
Journal of neurosurgery 2011;114(3):633-9.
2011: Paul Porensky; E Antonio Chiocca
Preoperative comorbidity scores and intangible neurosurgical wisdom.
World neurosurgery 2011;75(2):215-6.
2011: Paul Porensky; E Antonio Chiocca
Performing quality research in an era of reforms.
Clinical neurosurgery 2011;58():72-8.
2011: Pierpaolo Peruzzi; Erika Puente; Sergio Bergese; E Antonio Chiocca
Intraoperative MRI (ioMRI) in the setting of awake craniotomies for supratentorial glioma resection.
Acta neurochirurgica. Supplement 2011;109():43-8.
2010: Kaveh Asadi-Moghaddam; E Antonio Chiocca; Sean E Lawler
Potential role of miRNAs and their inhibitors in glioma treatment.
Expert review of anticancer therapy 2010;10(11):1753-62.
2010: Pierpaolo Peruzzi; E Antonio Chiocca
Treating glioblastoma multiforme with electrical fields.
World neurosurgery 2010;74(2-3):208-11.
2010: E Antonio Chiocca
Monoclonal antibodies.
Journal of neurosurgery 2010;113(2):190; discussion 190-1.
2010: E Antonio Chiocca
Neurosurgical "pearls" and neurosurgical evidence.
Journal of neurosurgery 2010;113(2):179; discussion 179-80.
2010: Jakub Godlewski; Agnieszka Bronisz; Michal O Nowicki; E Antonio Chiocca; Sean Lawler
microRNA-451: A conditional switch controlling glioma cell proliferation and migration.
Cell cycle (Georgetown, Tex.) 2010;9(14):2742-8.
2010: E Antonio Chiocca; Sean E Lawler
The many functions of microRNAs in glioblastoma.
World neurosurgery 2010;73(6):598-601.
2010: Judith A Schwartzbaum; Kun Huang; Sean Lawler; Bo Ding; Jianhua Yu; E Antonio Chiocca
Allergy and inflammatory transcriptome is predominantly negatively correlated with CD133 expression in glioblastoma.
Neuro-oncology 2010;12(4):320-7.
2010: Hiroshi Nakashima; Balveen Kaur; E Antonio Chiocca
Directing systemic oncolytic viral delivery to tumors via carrier cells.
Cytokine & growth factor reviews 2010;21(2-3):119-26.
2010: Jakub Godlewski; Michal O Nowicki; Agnieszka Bronisz; Gerard Nuovo; Jeff Palatini; Michael De Lay; James Van Brocklyn; Michael C Ostrowski; E Antonio Chiocca; Sean E Lawler
MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells.
Molecular cell 2010;37(5):620-32.
2010: Jayson Hardcastle; Kazuhiko Kurozumi; Nina Dmitrieva; Martin P Sayers; Sarwat Ahmad; Peter Waterman; Ralph Weissleder; E Antonio Chiocca; Balveen Kaur
Enhanced antitumor efficacy of vasculostatin (Vstat120) expressing oncolytic HSV-1.
Molecular therapy : the journal of the American Society of Gene Therapy 2010;18(2):285-94.
2009: Benjamin Kefas; Laurey Comeau; Desiree H Floyd; Oleksandr Seleverstov; Jakub Godlewski; Tom Schmittgen; Jinmai Jiang; Charles G diPierro; Yunqing Li; E Antonio Chiocca; Jeongwu Lee; Howard Fine; Roger Abounader; Sean Lawler; Benjamin Purow
The neuronal microRNA miR-326 acts in a feedback loop with notch and has therapeutic potential against brain tumors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(48):15161-8.
2009: Jed Johnson; Michal O Nowicki; Carol H Lee; E Antonio Chiocca; Mariano S Viapiano; Sean E Lawler; John Lannutti
Quantitative analysis of complex glioma cell migration on electrospun polycaprolactone using time-lapse microscopy.
Tissue engineering. Part C, Methods 2009;15(4):531-40.
2009: Yangjin Kim; Sean Lawler; Michal O Nowicki; E Antonio Chiocca; Avner Friedman
A mathematical model for pattern formation of glioma cells outside the tumor spheroid core.
Journal of theoretical biology 2009;260(3):359-71.
2009: Balveen Kaur; Timothy P Cripe; E Antonio Chiocca
"Buy one get one free": armed viruses for the treatment of cancer cells and their microenvironment.
Current gene therapy 2009;9(5):341-55.
2009: Pier Paolo Peruzzi; Sean E Lawler; Steve L Senior; Nina Dmitrieva; Pauline A H Edser; Davide Gianni; E Antonio Chiocca; Richard Wade-Martins
Physiological transgene regulation and functional complementation of a neurological disease gene deficiency in neurons.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(9):1517-26.
2009: Bakri Elsheikh; John T Kissel; Gregory Christoforidis; Matthew Wicklund; Dimitri T Kehagias; E Antonio Chiocca; Jerry R Mendell
Spinal angiography and epidural venography in juvenile muscular atrophy of the distal arm "Hirayama disease".
Muscle & nerve 2009;40(2):206-12.
2009: Pierpaolo Peruzzi; Abhik Ray-Chaudhuri; Wayne H Slone; Hagop S Mekhjian; Pierluigi Porcu; E Antonio Chiocca
Reversal of neurological deficit after chemotherapy in BCL-6-positive neurolymphomatosis. Case report.
Journal of neurosurgery 2009;111(2):247-51.
2009: Robert A Hirschl; Jeff Wilson; Brandon Miller; Sergio Bergese; E Antonio Chiocca
The predictive value of low-field strength magnetic resonance imaging for intraoperative residual tumor detection. Clinical article.
Journal of neurosurgery 2009;111(2):252-7.
2009: Kaveh Asadi-Moghaddam; E Antonio Chiocca
Gene- and viral-based therapies for brain tumors.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2009;6(3):547-57.
2009: Christopher Alvarez-Breckenridge; Balveen Kaur; E Antonio Chiocca
Pharmacologic and chemical adjuvants in tumor virotherapy.
Chemical reviews 2009;109(7):3125-40.
2009: Tanmay R Patel; E Antonio Chiocca; Miriam L Freimer; Gregory A Christoforidis
Lack of epidural pressure change with neck flexion in a patient with Hirayama disease: case report.
Neurosurgery 2009;64(6):E1196-7; discussion E1197.
2009: Sean Lawler; E Antonio Chiocca
Emerging functions of microRNAs in glioblastoma.
Journal of neuro-oncology 2009;92(3):297-306.
2009: Paola Grandi; Pierpaolo Peruzzi; Bonnie Reinhart; Justus B Cohen; E Antonio Chiocca; Joseph C Glorioso
Design and application of oncolytic HSV vectors for glioblastoma therapy.
Expert review of neurotherapeutics 2009;9(4):505-17.
2009: Masataka Suzuki; Kazue Kasai; Akihiro Ohtsuki; Jakub Godlewski; Michal O Nowicki; E Antonio Chiocca; Yoshinaga Saeki
ICP0 inhibits the decrease of HSV amplicon-mediated transgene expression.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(4):707-15.
2009: Jianjun Paul Tian; Avner Friedman; Jin Wang; E Antonio Chiocca
Modeling the effects of resection, radiation and chemotherapy in glioblastoma.
Journal of neuro-oncology 2009;91(3):287-93.
2009: Shigeru Tanaka; Imran Mohammed Shaikh; E Antonio Chiocca; Yoshinaga Saeki
The Gs-linked receptor GPR3 inhibits the proliferation of cerebellar granule cells during postnatal development.
PloS one 2009;4(6):e5922.
2009: Manish K Aghi; E Antonio Chiocca
Phase ib trial of oncolytic herpes virus G207 shows safety of multiple injections and documents viral replication.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(1):8-9.
2008: Jakub Godlewski; Michal O Nowicki; Agnieszka Bronisz; Shanté Williams; Akihiro Otsuki; Gerard J Nuovo; Abhik RayChaudhury; Herbert B Newton; E Antonio Chiocca; Sean Lawler
Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal.
Cancer research 2008;68(22):9125-30.
2008: Masataka Suzuki; E Antonio Chiocca; Yoshinaga Saeki
Stable transgene expression from HSV amplicon vectors in the brain: potential involvement of immunoregulatory signals.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(10):1727-36.
2008: Michal O Nowicki; Nina Dmitrieva; Andrew M Stein; Jennifer L Cutter; Jakub Godlewski; Yoshinaga Saeki; Masayuki Nita; Michael Berens; Leonard M Sander; Herbert B Newton; E Antonio Chiocca; Sean Lawler
Lithium inhibits invasion of glioma cells; possible involvement of glycogen synthase kinase-3.
Neuro-oncology 2008;10(5):690-9.
2008: Akihiro Otsuki; Ankita Patel; Kazue Kasai; Masataka Suzuki; Kazuhiko Kurozumi; E Antonio Chiocca; Yoshinaga Saeki
Histone deacetylase inhibitors augment antitumor efficacy of herpes-based oncolytic viruses.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(9):1546-55.
2008: Kazuhiko Kurozumi; Jayson Hardcastle; Roopa Thakur; Joshua Shroll; Michal Nowicki; Akihiro Otsuki; E Antonio Chiocca; Balveen Kaur
Oncolytic HSV-1 infection of tumors induces angiogenesis and upregulates CYR61.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(8):1382-91.
2008: Manish Aghi; Therese Visted; Ronald A DePinho; E Antonio Chiocca
Oncolytic herpes virus with defective ICP6 specifically replicates in quiescent cells with homozygous genetic mutations in p16.
Oncogene 2008;27(30):4249-54.
2008: Benjamin Kefas; Jakub Godlewski; Laurey Comeau; Yunqing Li; Roger Abounader; Michael Hawkinson; Jeongwu Lee; Howard A Fine; E Antonio Chiocca; Sean Lawler; Benjamin Purow
microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma.
Cancer research 2008;68(10):3566-72.
2008: Mark A Currier; Rebecca A Gillespie; Nancy M Sawtell; Yonatan Y Mahller; Greg Stroup; Margaret H Collins; Hirokazu Kambara; E Antonio Chiocca; Timothy P Cripe
Efficacy and safety of the oncolytic herpes simplex virus rRp450 alone and combined with cyclophosphamide.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(5):879-85.
2008: E Antonio Chiocca
Being old is no fun: treatment of glioblastoma multiforme in the elderly.
Journal of neurosurgery 2008;108(4):639-40.
2008: Promod Pillai; Abhik Ray-Chaudhury; Mario Ammirati; E Antonio Chiocca
Solitary pituitary sarcoidosis with normal endocrine function: case report.
Journal of neurosurgery 2008;108(3):591-4.
2008: E Antonio Chiocca; Katie M Smith; Byron McKinney; Cheryl A Palmer; Steven Rosenfeld; Kevin Lillehei; Allan Hamilton; Betty K DeMasters; Kevin Judy; David Kirn
A phase I trial of Ad.hIFN-beta gene therapy for glioma.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(3):618-26.
2008: E Antonio Chiocca
The host response to cancer virotherapy.
Current opinion in molecular therapeutics 2008;10(1):38-45.
2007: Kazuhiko Kurozumi; Jayson Hardcastle; Roopa Thakur; Ming Yang; Gregory Christoforidis; Giulia Fulci; Fred H Hochberg; Ralph Weissleder; William Carson; E Antonio Chiocca; Balveen Kaur
Effect of tumor microenvironment modulation on the efficacy of oncolytic virus therapy.
Journal of the National Cancer Institute 2007;99(23):1768-81.
2007: David Dang; Mirza N Baig; Gregory A Christoforidis; E Antonio Chiocca; Joshue Gabriel
C2/C3 pathologic fractures from polyostotic fibrous dysplasia of the cervical spine treated with percutaneous vertebroplasty.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2007;16 Suppl 3():250-4.
2007: Masataka Suzuki; E Antonio Chiocca; Yoshinaga Saeki
Early STAT1 activation after systemic delivery of HSV amplicon vectors suppresses transcription of the vector-encoded transgene.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(11):2017-26.
2007: Giulia Fulci; Nina Dmitrieva; Davide Gianni; Elisabeth J Fontana; Xiaogang Pan; Yanhui Lu; Claire S Kaufman; Balveen Kaur; Sean E Lawler; Robert J Lee; Clay B Marsh; Daniel J Brat; Nico van Rooijen; Anat Stemmer-Rachamimov; Anat Stemmer Rachamimov; Fred H Hochberg; Ralph Weissleder; Robert L Martuza; E Antonio Chiocca
Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses.
Cancer research 2007;67(19):9398-406.
2007: Andrew M Stein; Michal O Nowicki; Tim Demuth; Michael Berens; Sean E Lawler; E Antonio Chiocca; Leonard M Sander
Estimating the cell density and invasive radius of three-dimensional glioblastoma tumor spheroids grown in vitro.
Applied optics 2007;46(22):5110-8.
2007: E Antonio Chiocca; Judith A Schwartzbaum
Gliomas and venous thromboembolism: how common?
Journal of neurosurgery 2007;106(4):599-600; discussion 600.
2007: Susan Chang; Michael A Vogelbaum; Frederick F Lang; Stephen Haines; Sandeep Kunwar; E Antonio Chiocca; Alessandro Olivi; A QUINONES-HINOJOSA; Andrew T Parsa; Ronald Warnick
GNOSIS: guidelines for neuro-oncology: standards for investigational studies--reporting of surgically based therapeutic clinical trials.
Journal of neuro-oncology 2007;82(2):211-20.
2007: Kelly Ishizuka; Anne Louise Oaklander; E Antonio Chiocca
A retrospective analysis of reasons for reoperation following initially successful peripheral nerve stimulation.
Journal of neurosurgery 2007;106(3):388-90.
2007: Jayson Hardcastle; Kazuhiko Kurozumi; E Antonio Chiocca; Balveen Kaur
Oncolytic viruses driven by tumor-specific promoters.
Current cancer drug targets 2007;7(2):181-9.
2007: Giulia Fulci; E Antonio Chiocca
The status of gene therapy for brain tumors.
Expert opinion on biological therapy 2007;7(2):197-208.
2007: Balveen Kaur; E Antonio Chiocca
Personalizing oncolytic virotherapy?
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(1):6-7.
2006: Balveen Kaur; E Antonio Chiocca
Oncolytic viruses: extreme treatment for an extreme disease.
Future microbiology 2006;1(4):351-3.
2006: Martine L M Lamfers; Giulia Fulci; Davide Gianni; Yi Tang; Kazuhiko Kurozumi; Balveen Kaur; Sharif Moeniralm; Yoshinaga Saeki; Jan E Carette; Ralph Weissleder; W Peter Vandertop; Victor W van Beusechem; Clemens M F Dirven; E Antonio Chiocca
Cyclophosphamide increases transgene expression mediated by an oncolytic adenovirus in glioma-bearing mice monitored by bioluminescence imaging.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(6):779-88.
2006: S Yamamoto; L A Deckter; K Kasai; E Antonio Chiocca; Y Saeki
Imaging immediate-early and strict-late promoter activity during oncolytic herpes simplex virus type 1 infection and replication in tumors.
Gene therapy 2006;13(24):1731-6.
2006: Manish Aghi; Kenneth S Cohen; Rachael J Klein; David T Scadden; E Antonio Chiocca
Tumor stromal-derived factor-1 recruits vascular progenitors to mitotic neovasculature, where microenvironment influences their differentiated phenotypes.
Cancer research 2006;66(18):9054-64.
2006: Giulia Fulci; Laura Breymann; Davide Gianni; Kazuhiko Kurozumi; Sarah S Rhee; Jianhua Yu; Balveen Kaur; David N Louis; Ralph Weissleder; Michael A Caligiuri; E Antonio Chiocca
Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(34):12873-8.
2006: Atom Sarkar; E Antonio Chiocca
Prognostic indicators.
Journal of neurosurgery 2006;105(2):161-2; discussion 162.
2006: Jennifer L Cutter; Kazuhiko Kurozumi; E Antonio Chiocca; Balveen Kaur
Gene therapeutics: the future of brain tumor therapy?
Expert review of anticancer therapy 2006;6(7):1053-64.
2006: W James Thoman; Mario Ammirati; Louis P Caragine; John M McGregor; Atom Sarkar; E Antonio Chiocca
Brain tumor imaging and surgical management: the neurosurgeon's perspective.
Topics in magnetic resonance imaging : TMRI 2006;17(2):121-6.
2006: Kinya Terada; Hiroaki Wakimoto; Edyta Tyminski; E Antonio Chiocca; Yoshinaga Saeki
Development of a rapid method to generate multiple oncolytic HSV vectors and their in vivo evaluation using syngeneic mouse tumor models.
Gene therapy 2006;13(8):705-14.
2006: S E Lawler; P P Peruzzi; E Antonio Chiocca
Genetic strategies for brain tumor therapy.
Cancer gene therapy 2006;13(3):225-33.
2006: Avner Friedman; Jianjun Paul Tian; Giulia Fulci; E Antonio Chiocca; Jin Wang
Glioma virotherapy: effects of innate immune suppression and increased viral replication capacity.
Cancer research 2006;66(4):2314-9.
2006: Manish Aghi; E Antonio Chiocca
Gene therapy for glioblastoma.
Neurosurgical focus 2006;20(4):E18.
2005: Hirokazu Kambara; Yoshinaga Saeki; E Antonio Chiocca
Cyclophosphamide allows for in vivo dose reduction of a potent oncolytic virus.
Cancer research 2005;65(24):11255-8.
2005: Manish Aghi; E Antonio Chiocca
Contribution of bone marrow-derived cells to blood vessels in ischemic tissues and tumors.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(6):994-1005.
2005: Martine L M Lamfers; Davide Gianni; Ching-Hsuan Tung; Sander Idema; Frederik H E Schagen; Jan E Carette; Paul H A Quax; Victor W van Beusechem; W Peter Vandertop; Clemens M F Dirven; E Antonio Chiocca; Winald Gerritsen
Tissue inhibitor of metalloproteinase-3 expression from an oncolytic adenovirus inhibits matrix metalloproteinase activity in vivo without affecting antitumor efficacy in malignant glioma.
Cancer research 2005;65(20):9398-405.
2005: Edyta Tyminski; Stanley Leroy; Kinya Terada; Dianne M Finkelstein; Janice L Hyatt; Mary K Danks; Philip Potter; Yoshinaga Saeki; E Antonio Chiocca
Brain tumor oncolysis with replication-conditional herpes simplex virus type 1 expressing the prodrug-activating genes, CYP2B1 and secreted human intestinal carboxylesterase, in combination with cyclophosphamide and irinotecan.
Cancer research 2005;65(15):6850-7.
2005: Hirokazu Kambara; Hideyuki Okano; E Antonio Chiocca; Yoshinaga Saeki
An oncolytic HSV-1 mutant expressing ICP34.5 under control of a nestin promoter increases survival of animals even when symptomatic from a brain tumor.
Cancer research 2005;65(7):2832-9.
2004: E Antonio Chiocca; Khalid M Abbed; Stephen B Tatter; David N Louis; Fred H Hochberg; Fred Barker; Jean Kracher; Stuart A Grossman; Joy D Fisher; Kathryn Carson; Mark L Rosenblum; Tom Mikkelsen; Jeff Olson; James Markert; Steven Rosenfeld; L Burt Nabors; Steven Brem; Surasak Phuphanich; Scott Freeman; Richard S. Kaplan; James Zwiebel
A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(5):958-66.
2004: E Antonio Chiocca; William C Broaddus; George T Gillies; Therese Visted; Martine L M Lamfers
Neurosurgical delivery of chemotherapeutics, targeted toxins, genetic and viral therapies in neuro-oncology.
Journal of neuro-oncology 2004;69(1-3):101-17.
2004: Tomotsugu Ichikawa; Kinya Terada; Takashi Tamiya; James P Basilion; E Antonio Chiocca; Isao Date
[Molecular imaging of transgene expression in brain tumors].
No shinkei geka. Neurological surgery 2004;32(8):805-24.
2004: R Inoue; K A Moghaddam; M Ranasinghe; Yoshinaga Saeki; E Antonio Chiocca; Richard Wade-Martins
Infectious delivery of the 132 kb CDKN2A/CDKN2B genomic DNA region results in correctly spliced gene expression and growth suppression in glioma cells.
Gene therapy 2004;11(15):1195-204.
2004: Ulf Nestler; Hiroaki Wakimoto; Fernando Siller-Lopez; Laura K Aguilar; Arnab Chakravarti; Alona Muzikansky; Anat Stemmer-Rachamimov; E Antonio Chiocca; Estuardo Aguilar-Cordova; Fred H Hochberg
The combination of adenoviral HSV TK gene therapy and radiation is effective in athymic mouse glioblastoma xenografts without increasing toxic side effects.
Journal of neuro-oncology 2004;67(1-2):177-88.
2004: Dawn E Post; Giulia Fulci; E Antonio Chiocca; Erwin Van Meir
Replicative oncolytic herpes simplex viruses in combination cancer therapies.
Current gene therapy 2004;4(1):41-51.
2004: Michael H Lev; Yelda Ozsunar; John W Henson; Amjad A Rasheed; Glenn Barest; Griffith R Harsh; Markus M Fitzek; E Antonio Chiocca; James D Rabinov; Andrew N Csavoy; Bruce R Rosen; Fred H Hochberg; Pamela W Schaefer; R Gilberto Gonzalez
Glial tumor grading and outcome prediction using dynamic spin-echo MR susceptibility mapping compared with conventional contrast-enhanced MR: confounding effect of elevated rCBV of oligodendrogliomas [corrected].
AJNR. American journal of neuroradiology 2004;25(2):214-21.
2004: Hiroaki Wakimoto; Giulia Fulci; Edyta Tyminski; E Antonio Chiocca
Altered expression of antiviral cytokine mRNAs associated with cyclophosphamide's enhancement of viral oncolysis.
Gene therapy 2004;11(2):214-23.
2004: E Antonio Chiocca; David J Waxman
Cytochrome p450-based gene therapies for cancer.
Methods in molecular medicine 2004;90():203-22.
2003: Shuji Kubo; Yoshinaga Saeki; E Antonio Chiocca; Kohnosuke Mitani
An HSV amplicon-based helper system for helper-dependent adenoviral vectors.
Biochemical and biophysical research communications 2003;307(4):826-30.
2003: E Antonio Chiocca
Gene therapy: a primer for neurosurgeons.
Neurosurgery 2003;53(2):364-73; discussion 373.
2003: Thomas S Deisboeck; Hiroaki Wakimoto; U Nestler; David N Louis; P K Sehgal; M Simon; E Antonio Chiocca; Fred H Hochberg
Development of a novel non-human primate model for preclinical gene vector safety studies. Determining the effects of intracerebral HSV-1 inoculation in the common marmoset: a comparative study.
Gene therapy 2003;10(15):1225-33.
2003: Scott D Packard; Joseph B Mandeville; Tomotsugu Ichikawa; Keiro Ikeda; Kinya Terada; Stephanie Niloff; E Antonio Chiocca; Bruce R Rosen; John J A Marota
Functional response of tumor vasculature to PaCO2: determination of total and microvascular blood volume by MRI.
Neoplasia (New York, N.Y.) 2003;5(4):330-8.
2003: Hiroaki Wakimoto; P R Johnson; D M Knipe; E Antonio Chiocca
Effects of innate immunity on herpes simplex virus and its ability to kill tumor cells.
Gene therapy 2003;10(11):983-90.
2003: E Antonio Chiocca; Manish Aghi; Giulia Fulci
Viral therapy for glioblastoma.
Cancer journal (Sudbury, Mass.) 2003;9(3):167-79.
2003: Jürgen A Hampl; Sara M Camp; Wojciech K Mydlarz; Monika Hampl; Tomotsuga Ichikawa; E Antonio Chiocca; David N Louis; Miguel Sena-Esteves; Xandra O Breakefield
Potentiated gene delivery to tumors using herpes simplex virus/Epstein-Barr virus/RV tribrid amplicon vectors.
Human gene therapy 2003;14(7):611-26.
2003: Tatsuya Abe; Kinya Terada; Hiroaki Wakimoto; Ryo Inoue; Edyta Tyminski; Robert Bookstein; James P Basilion; E Antonio Chiocca
PTEN decreases in vivo vascularization of experimental gliomas in spite of proangiogenic stimuli.
Cancer research 2003;63(9):2300-5.
2003: Richard Wade-Martins; Yoshinaga Saeki; E Antonio Chiocca
Infectious delivery of a 135-kb LDLR genomic locus leads to regulated complementation of low-density lipoprotein receptor deficiency in human cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(5 Pt 1):604-12.
2003: Giulia Fulci; E Antonio Chiocca
Oncolytic viruses for the therapy of brain tumors and other solid malignancies: a review.
Frontiers in bioscience : a journal and virtual library 2003;8():e346-60.
2003: Manish Aghi; E Antonio Chiocca
Genetically engineered herpes simplex viral vectors in the treatment of brain tumors: a review.
Cancer investigation 2003;21(2):278-92.
2003: Yoshinaga Saeki; Xandra O Breakefield; E Antonio Chiocca
Improved HSV-1 amplicon packaging system using ICP27-deleted, oversized HSV-1 BAC DNA.
Methods in molecular medicine 2003;76():51-60.
2002: James D Rabinov; Patricia Lani Lee; Fred G Barker; David N Louis; Griffith R Harsh; G Rees Cosgrove; E Antonio Chiocca; Allan F Thornton; Jay S Loeffler; John W Henson; R Gilberto Gonzalez
In vivo 3-T MR spectroscopy in the distinction of recurrent glioma versus radiation effects: initial experience.
Radiology 2002;225(3):871-9.
2002: E Antonio Chiocca
Oncolytic viruses.
Nature reviews. Cancer 2002;2(12):938-50.
2002: Tomotsugu Ichikawa; Dagmar Högemann; Yoshinaga Saeki; Edyta Tyminski; Kinya Terada; Ralph Weissleder; E Antonio Chiocca; James P Basilion
MRI of transgene expression: correlation to therapeutic gene expression.
Neoplasia (New York, N.Y.) 2002;4(6):523-30.
2002: Timothy M Pawlik; Hideo Nakamura; John T Mullen; Hideki Kasuya; Sam S Yoon; Soundararajalu Chandrasekhar; E Antonio Chiocca; Kenneth K Tanabe
Prodrug bioactivation and oncolysis of diffuse liver metastases by a herpes simplex virus 1 mutant that expresses the CYP2B1 transgene.
Cancer 2002;95(5):1171-81.
2002: Hideo Nakamura; Hideki Kasuya; John T Mullen; Sam S Yoon; Timothy M Pawlik; Soundararajalu Chandrasekhar; James M Donahue; E Antonio Chiocca; Richard Y Chung; Kenneth K Tanabe
Regulation of herpes simplex virus gamma(1)34.5 expression and oncolysis of diffuse liver metastases by Myb34.5.
The Journal of clinical investigation 2002;109(7):871-82.
2002: Tatsuya Abe; Hiroaki Wakimoto; Robert Bookstein; Daniel Maneval; E Antonio Chiocca; James P Basilion
Intra-arterial delivery of p53-containing adenoviral vector into experimental brain tumors.
Cancer gene therapy 2002;9(3):228-35.
2002: E Antonio Chiocca
Guided genes for tumor warfare.
Nature biotechnology 2002;20(3):235-6.
2002: Hiroaki Wakimoto; Keiro Ikeda; Tatsuya Abe; Tomotsugu Ichikawa; Fred H Hochberg; R Alan B Ezekowitz; Mark S Pasternack; E Antonio Chiocca
The complement response against an oncolytic virus is species-specific in its activation pathways.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(3):275-82.
2002: Edward R Smith; Mark Ott; John Wain; David N Louis; E Antonio Chiocca
Massive growth of a meningioma into the brachial plexus and thoracic cavity after intraspinal and supraclavicular resection. Case report and review of the literature.
Journal of neurosurgery 2002;96(1 Suppl):107-11.
2001: Richard Wade-Martins; E R Smith; Edyta Tyminski; E Antonio Chiocca; Yoshinaga Saeki
An infectious transfer and expression system for genomic DNA loci in human and mouse cells.
Nature biotechnology 2001;19(11):1067-70.
2001: Tomotsugu Ichikawa; E Antonio Chiocca
Comparative analyses of transgene delivery and expression in tumors inoculated with a replication-conditional or -defective viral vector.
Cancer research 2001;61(14):5336-9.
2001: Y Saeki; C Fraefel; T Ichikawa; X O Breakefield; E Antonio Chiocca
Improved helper virus-free packaging system for HSV amplicon vectors using an ICP27-deleted, oversized HSV-1 DNA in a bacterial artificial chromosome.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(4):591-601.
2001: A Jacobs; Juri Gelovani Tjuvajev; M Dubrovin; Timothy Akhurst; Julius Balatoni; Bradley Beattie; R Joshi; Ronald Finn; Steven M Larson; Ulrich Herrlinger; Peter Pechan; E Antonio Chiocca; Xandra O Breakefield; Ronald Blasberg
Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo.
Cancer research 2001;61(7):2983-95.
2001: Tomotsugu Ichikawa; William P Petros; Susan M Ludeman; J Fangmeier; Fred H Hochberg; O Michael Colvin; E Antonio Chiocca
Intraneoplastic polymer-based delivery of cyclophosphamide for intratumoral bioconversion by a replicating oncolytic viral vector.
Cancer research 2001;61(3):864-8.
2000: Joseph Misdraji; Yasushi Ino; David N Louis; Andrew E Rosenberg; E Antonio Chiocca; Nancy Lee Harris
Primary lymphoma of peripheral nerve: report of four cases.
The American journal of surgical pathology 2000;24(9):1257-65.
2000: Timothy M Pawlik; Hideo Nakamura; Sam S Yoon; John T Mullen; Soundararajalu Chandrasekhar; E Antonio Chiocca; Kenneth K Tanabe
Oncolysis of diffuse hepatocellular carcinoma by intravascular administration of a replication-competent, genetically engineered herpesvirus.
Cancer research 2000;60(11):2790-5.
2000: Griffith R Harsh; Thomas S Deisboeck; David N Louis; J Hilton; M Colvin; JS Silver; NH Qureshi; J Kracher; D Finkelstein; E Antonio Chiocca; Fred H Hochberg
Thymidine kinase activation of ganciclovir in recurrent malignant gliomas: a gene-marking and neuropathological study.
Journal of neurosurgery 2000;92(5):804-11.
2000: Keiro Ikeda; Hiroaki Wakimoto; Tomotsugu Ichikawa; S Jhung; Fred H Hochberg; David N Louis; E Antonio Chiocca
Complement depletion facilitates the infection of multiple brain tumors by an intravascular, replication-conditional herpes simplex virus mutant.
Journal of virology 2000;74(10):4765-75.
2000: NH Qureshi; Krystof Bankiewicz; David N Louis; Fred H Hochberg; E Antonio Chiocca; Griffith R Harsh
Multicolumn infusion of gene therapy cells into human brain tumors: technical report.
Neurosurgery 2000;46(3):663-8; discussion 668-9.
2000: Ralph Weissleder; Anna Moore; Umar Mahmood; RM Bhorade; Helene Benveniste; E Antonio Chiocca; James P Basilion
In vivo magnetic resonance imaging of transgene expression.
Nature medicine 2000;6(3):351-5.
2000: E R Smith; E Antonio Chiocca
Oncolytic viruses as novel anticancer agents: turning one scourge against another.
Expert opinion on investigational drugs 2000;9(2):311-27.
2000: Sam S Yoon; Hideo Nakamura; Nancy M Carroll; B P Bode; E Antonio Chiocca; Kenneth K Tanabe
An oncolytic herpes simplex virus type 1 selectively destroys diffuse liver metastases from colon carcinoma.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(2):301-11.
2000: A QUINONES-HINOJOSA; Robert M Friedlander; P J Boyer; Tracy T Batchelor; E Antonio Chiocca
Solitary sciatic nerve lymphoma as an initial manifestation of diffuse neurolymphomatosis. Case report and review of the literature.
Journal of neurosurgery 2000;92(1):165-9.
1999: Miguel Sena-Esteves; Y Saeki; Sara M Camp; E Antonio Chiocca; Xandra O Breakefield
Single-step conversion of cells to retrovirus vector producers with herpes simplex virus-Epstein-Barr virus hybrid amplicons.
Journal of virology 1999;73(12):10426-39.
1999: Richard Y Chung; Y Saeki; E Antonio Chiocca
B-myb promoter retargeting of herpes simplex virus gamma34.5 gene-mediated virulence toward tumor and cycling cells.
Journal of virology 1999;73(9):7556-64.
1999: Manish Aghi; T C Chou; K Suling; Xandra O Breakefield; E Antonio Chiocca
Multimodal cancer treatment mediated by a replicating oncolytic virus that delivers the oxazaphosphorine/rat cytochrome P450 2B1 and ganciclovir/herpes simplex virus thymidine kinase gene therapies.
Cancer research 1999;59(16):3861-5.
1999: Keiro Ikeda; Tomotsugu Ichikawa; Hiroaki Wakimoto; JS Silver; Thomas S Deisboeck; D Finkelstein; Griffith R Harsh; David N Louis; raymond bartus; Fred H Hochberg; E Antonio Chiocca
Oncolytic virus therapy of multiple tumors in the brain requires suppression of innate and elicited antiviral responses.
Nature medicine 1999;5(8):881-7.
1999: K Ikeda; Y Saeki; C Gonzalez-Agosti; Vijaya Ramesh; E Antonio Chiocca
Inhibition of NF2-negative and NF2-positive primary human meningioma cell proliferation by overexpression of merlin due to vector-mediated gene transfer.
Journal of neurosurgery 1999;91(1):85-92.
1999: Nikolai G Rainov; K Ikeda; NH Qureshi; S Grover; Ulrich Herrlinger; Peter Pechan; E Antonio Chiocca; Xandra O Breakefield; FH Barnett
Intraarterial delivery of adenovirus vectors and liposome-DNA complexes to experimental brain neoplasms.
Human gene therapy 1999;10(2):311-8.
1999: NH Qureshi; E Antonio Chiocca
A review of gene therapy for the treatment of central nervous system tumors.
Critical reviews in oncogenesis 1999;10(4):261-74.
1999: Nikolai G Rainov; K Ikeda; N Qureshi; S Grover; FH Barnett; Ulrich Herrlinger; Ariel Quinones; E Antonio Chiocca; Xandra O Breakefield
Intra-arterial virus and nonvirus vector-mediated gene transfer to experimental rat brain tumors.
Frontiers of radiation therapy and oncology 1999;33():227-40.
1999: Sam S Yoon; Nancy M Carroll; E Antonio Chiocca; Kenneth K Tanabe
Influence of p53 on herpes simplex virus type 1 vectors for cancer gene therapy.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 1999;3(1):34-48.
1999: FH Barnett; Nikolai G Rainov; K Ikeda; D E Schuback; P Elliott; Christof M Kramm; M Chase; NH Qureshi; Griffith R Harsh; E Antonio Chiocca; Xandra O Breakefield
Selective delivery of herpes virus vectors to experimental brain tumors using RMP-7.
Cancer gene therapy 1999;6(1):14-20.
1998: Yoshinaga Saeki; T Ichikawa; A Saeki; E Antonio Chiocca; Kurt Tobler; Mathias Ackermann; Xandra O Breakefield; Cornel Fraefel
Herpes simplex virus type 1 DNA amplified as bacterial artificial chromosome in Escherichia coli: rescue of replication-competent virus progeny and packaging of amplicon vectors.
Human gene therapy 1998;9(18):2787-94.
1998: Sam S Yoon; Nancy M Carroll; E Antonio Chiocca; Kenneth K Tanabe
Cancer gene therapy using a replication-competent herpes simplex virus type 1 vector.
Annals of surgery 1998;228(3):366-74.
1998: Richard Y Chung; E Antonio Chiocca
Gene therapy for tumors of the central nervous system.
Surgical oncology clinics of North America 1998;7(3):589-602.
1998: Nikolai G Rainov; Karl-Ulrich Dobberstein; Miguel Sena-Esteves; Ulrich Herrlinger; Christof M Kramm; R M Philpot; J Hilton; E Antonio Chiocca; Xandra O Breakefield
New prodrug activation gene therapy for cancer using cytochrome P450 4B1 and 2-aminoanthracene/4-ipomeanol.
Human gene therapy 1998;9(9):1261-73.
1998: Ulrich Herrlinger; Christof M Kramm; KS Aboody-Guterman; JS Silver; Keiro Ikeda; KM Johnston; Peter Pechan; R F Barth; D Finkelstein; E Antonio Chiocca; David N Louis; Xandra O Breakefield
Pre-existing herpes simplex virus 1 (HSV-1) immunity decreases, but does not abolish, gene transfer to experimental brain tumors by a HSV-1 vector.
Gene therapy 1998;5(6):809-19.
1998: Nikolai G Rainov; Karl-Ulrich Dobberstein; Volkmar Heidecke; U Dorant; M Chase; Christof M Kramm; E Antonio Chiocca; Xandra O Breakefield
Long-term survival in a rodent brain tumor model by bradykinin-enhanced intra-arterial delivery of a therapeutic herpes simplex virus vector.
Cancer gene therapy 1998;5(3):158-62.
1998: M Chase; Richard Y Chung; E Antonio Chiocca
An oncolytic viral mutant that delivers the CYP2B1 transgene and augments cyclophosphamide chemotherapy.
Nature biotechnology 1998;16(5):444-8.
1998: Anna Moore; James P Basilion; E Antonio Chiocca; Ralph Weissleder
Measuring transferrin receptor gene expression by NMR imaging.
Biochimica et biophysica acta 1998;1402(3):239-49.
1998: M X Wei; F Li; Y Ono; J Gauldie; E Antonio Chiocca
Effects on brain tumor cell proliferation by an adenovirus vector that bears the interleukin-4 gene.
Journal of neurovirology 1998;4(2):237-41.
1998: Manish Aghi; Christof M Kramm; T C Chou; Xandra O Breakefield; E Antonio Chiocca
Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies.
Journal of the National Cancer Institute 1998;90(5):370-80.
1998: Nikolai G Rainov; Miguel Sena-Esteves; Cornel Fraefel; Karl-Ulrich Dobberstein; E Antonio Chiocca; Xandra O Breakefield
A chimeric fusion protein of cytochrome CYP4B1 and green fluorescent protein for detection of pro-drug activating gene delivery and for gene therapy in malignant glioma.
Advances in experimental medicine and biology 1998;451():393-403.
1997: Christof M Kramm; M Chase; Ulrich Herrlinger; A Jacobs; Peter Pechan; Nikolai G Rainov; Miguel Sena-Esteves; Manish Aghi; FH Barnett; E Antonio Chiocca; Xandra O Breakefield
Therapeutic efficiency and safety of a second-generation replication-conditional HSV1 vector for brain tumor gene therapy.
Human gene therapy 1997;8(17):2057-68.
1997: Y Ono; K Ikeda; M X Wei; G R Harsh; Takashi Tamiya; E Antonio Chiocca
Regression of experimental brain tumors with 6-thioxanthine and Escherichia coli gpt gene therapy.
Human gene therapy 1997;8(17):2043-55.
1997: Nancy M Carroll; M Chase; E Antonio Chiocca; Kenneth K Tanabe
The effect of ganciclovir on herpes simplex virus-mediated oncolysis.
The Journal of surgical research 1997;69(2):413-7.
1996: Peter Pechan; M Fotaki; R L Thompson; R Dunn; M Chase; E Antonio Chiocca; Xandra O Breakefield
A novel 'piggyback' packaging system for herpes simplex virus amplicon vectors.
Human gene therapy 1996;7(16):2003-13.
1996: Christof M Kramm; Nikolai G Rainov; Miguel Sena-Esteves; FH Barnett; M Chase; Ulrich Herrlinger; Peter Pechan; E Antonio Chiocca; Xandra O Breakefield
Long-term survival in a rodent model of disseminated brain tumors by combined intrathecal delivery of herpes vectors and ganciclovir treatment.
Human gene therapy 1996;7(16):1989-94.
1996: Nancy M Carroll; E Antonio Chiocca; K Takahashi; Kenneth K Tanabe
Enhancement of gene therapy specificity for diffuse colon carcinoma liver metastases with recombinant herpes simplex virus.
Annals of surgery 1996;224(3):323-9; discussion 329-30.
1996: Takashi Tamiya; Y Ono; M X Wei; P J Mroz; F L Moolten; E Antonio Chiocca
Escherichia coli gpt gene sensitizes rat glioma cells to killing by 6-thioxanthine or 6-thioguanine.
Cancer gene therapy 1996;3(3):155-62.
1996: Christof M Kramm; Nikolai G Rainov; Miguel Sena-Esteves; M Chase; Peter Pechan; E Antonio Chiocca; Xandra O Breakefield
Herpes vector-mediated delivery of marker genes to disseminated central nervous system tumors.
Human gene therapy 1996;7(3):291-300.
1995: Nikolai G Rainov; C Zimmer; M Chase; Christof M Kramm; E Antonio Chiocca; Ralph Weissleder; Xandra O Breakefield
Selective uptake of viral and monocrystalline particles delivered intra-arterially to experimental brain neoplasms.
Human gene therapy 1995;6(12):1543-52.
1995: M X Wei; Takashi Tamiya; R J Rhee; Xandra O Breakefield; E Antonio Chiocca
Diffusible cytotoxic metabolites contribute to the in vitro bystander effect associated with the cyclophosphamide/cytochrome P450 2B1 cancer gene therapy paradigm.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(10):1171-7.
1995: Christof M Kramm; Miguel Sena-Esteves; FH Barnett; Nikolai G Rainov; D E Schuback; J S Yu; Peter Pechan; W Paulus; E Antonio Chiocca; Xandra O Breakefield
Gene therapy for brain tumors.
Brain pathology (Zurich, Switzerland) 1995;5(4):345-81.
1995: Takashi Tamiya; M X Wei; M Chase; Y Ono; F Lee; Xandra O Breakefield; E Antonio Chiocca
Transgene inheritance and retroviral infection contribute to the efficiency of gene expression in solid tumors inoculated with retroviral vector producer cells.
Gene therapy 1995;2(8):531-8.
1995: M X Wei; Takashi Tamiya; R K Hurford; E J Boviatsis; R I Tepper; E Antonio Chiocca
Enhancement of interleukin-4-mediated tumor regression in athymic mice by in situ retroviral gene transfer.
Human gene therapy 1995;6(4):437-43.
1994: E J Boviatsis; J S Park; Miguel Sena-Esteves; Christof M Kramm; M Chase; J T Efird; M X Wei; Xandra O Breakefield; E Antonio Chiocca
Long-term survival of rats harboring brain neoplasms treated with ganciclovir and a herpes simplex virus vector that retains an intact thymidine kinase gene.
Cancer research 1994;54(22):5745-51.
1994: E Antonio Chiocca; E J Boviatsis; R M Westmark; M P Short; E P Richardson; Nicholas T Zervas
Deep sylvian fissure meningioma without dural attachment in an adult: case report.
Neurosurgery 1994;35(5):944-6; discussion 946.
1994: E J Boviatsis; J M Scharf; M Chase; K Harrington; Neil W Kowall; Xandra O Breakefield; E Antonio Chiocca
Antitumor activity and reporter gene transfer into rat brain neoplasms inoculated with herpes simplex virus vectors defective in thymidine kinase or ribonucleotide reductase.
Gene therapy 1994;1(5):323-31.
1994: M X Wei; Takashi Tamiya; M Chase; E J Boviatsis; T K Chang; Neil W Kowall; F H Hochberg; D J Waxman; Xandra O Breakefield; E Antonio Chiocca
Experimental tumor therapy in mice using the cyclophosphamide-activating cytochrome P450 2B1 gene.
Human gene therapy 1994;5(8):969-78.
1994: E J Boviatsis; M Chase; M X Wei; Takashi Tamiya; R K Hurford; Neil W Kowall; R I Tepper; Xandra O Breakefield; E Antonio Chiocca
Gene transfer into experimental brain tumors mediated by adenovirus, herpes simplex virus, and retrovirus vectors.
Human gene therapy 1994;5(2):183-91.
1993: J S Yu; M X Wei; E Antonio Chiocca; R L Martuza; R I Tepper
Treatment of glioma by engineered interleukin 4-secreting cells.
Cancer research 1993;53(13):3125-8.
1992: J K Lee; R A Sobel; E Antonio Chiocca; T S Kim; R L Martuza
Growth of human acoustic neuromas, neurofibromas and schwannomas in the subrenal capsule and sciatic nerve of the nude mouse.
Journal of neuro-oncology 1992;14(2):101-12.
1991: Vittorio Gentile; M Saydak; E Antonio Chiocca; O Akande; P J Birckbichler; K N Lee; J P Stein; Peter Davies
Isolation and characterization of cDNA clones to mouse macrophage and human endothelial cell tissue transglutaminases.
The Journal of biological chemistry 1991;266(1):478-83.
1990: J K Lee; B Choi; R A Sobel; E Antonio Chiocca; R L Martuza
Inhibition of growth and angiogenesis of human neurofibrosarcoma by heparin and hydrocortisone.
Journal of neurosurgery 1990;73(3):429-35.
1990: E Antonio Chiocca; B B Choi; W Z Cai; Neal A DeLuca; Priscilla A Schaffer; Marian DiFiglia; Xandra O Breakefield; R L Martuza
Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants.
The New biologist 1990;2(8):739-46.
1990: J K Lee; T S Kim; E Antonio Chiocca; A Medhkour; R L Martuza
Growth of human schwannomas in the subrenal capsule of the nude mouse.
Neurosurgery 1990;26(4):598-605.
1989: E Antonio Chiocca; Peter Davies; J P Stein
Regulation of tissue transglutaminase gene expression as a molecular model for retinoid effects on proliferation and differentiation.
Journal of cellular biochemistry 1989;39(3):293-304.
1988: Peter Davies; J P Basilion; E Antonio Chiocca; J Johnson; S Poddar; J P Stein
Retinoids as generalized regulators of cellular growth and differentiation.
The American journal of the medical sciences 1988;296(3):164-70.
1988: E Antonio Chiocca; Peter Davies; J P Stein
The molecular basis of retinoic acid action. Transcriptional regulation of tissue transglutaminase gene expression in macrophages.
The Journal of biological chemistry 1988;263(23):11584-9.
1988: Peter Davies; E Antonio Chiocca; J P Basilion; S Poddar; J P Stein
Transglutaminases and their regulation: implications for polyamine metabolism.
Advances in experimental medicine and biology 1988;250():391-401.
1988: Peter Davies; E Antonio Chiocca; J P Stein
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