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Narendra Chirmule

Research Profile

Chemicals & Drugs

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Sarah A Hoofring; Arunan Kaliyaperumal; Rocio Lopez; Sonal K Patel; Narendra Chirmule; M Benjamin Hock; Steven J Swanson; Marta Starcevic
Immunogenicity testing strategy and bioanalytical assays for antibody-drug conjugates.
Dohan K Weeraratne; Narendra Chirmule; Andrew J Kuck; Daniel T Mytych
Measurement of anti-erythropoiesis-stimulating agent IgG4 antibody as an indicator of antibody-mediated pure red cell aplasia.
Lei Zhou; Steven J Swanson; Thuy Vu; Yu Wu; Narendra Chirmule; Sarah A Hoofring; Peiming Ma; Marta Starcevic
Stratification of antibody-positive subjects by antibody level reveals an impact of immunogenicity on pharmacokinetics.

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2013: Sarah A Hoofring; Arunan Kaliyaperumal; Rocio Lopez; Sonal K Patel; Narendra Chirmule; M Benjamin Hock; Steven J Swanson; Marta Starcevic
Immunogenicity testing strategy and bioanalytical assays for antibody-drug conjugates.
Bioanalysis 2013;5(9):1041-55.
2013: Dohan K Weeraratne; Narendra Chirmule; Andrew J Kuck; Daniel T Mytych
Measurement of anti-erythropoiesis-stimulating agent IgG4 antibody as an indicator of antibody-mediated pure red cell aplasia.
Clinical and vaccine immunology : CVI 2013;20(1):46-51.
2013: Lei Zhou; Steven J Swanson; Thuy Vu; Yu Wu; Narendra Chirmule; Sarah A Hoofring; Peiming Ma; Marta Starcevic
Stratification of antibody-positive subjects by antibody level reveals an impact of immunogenicity on pharmacokinetics.
The AAPS journal 2013;15(1):30-40.
2012: Narendra Chirmule; Vibha Jawa; Bernd Meibohm
Immunogenicity to therapeutic proteins: impact on PK/PD and efficacy.
The AAPS journal 2012;14(2):296-302.
2012: Troy E Barger; Narendra Chirmule; Andrew J Kuck; Steven J Swanson; Daniel T Mytych
Detection of anti-ESA antibodies in human samples from PRCA and non-PRCA patients: an immunoassay platform comparison.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2012;27(2):688-93.
2011: Dohan Weeraratne; Jacqueline Wright; Chi-Yuan Wu; Bing-Bing Yang; Kathy Zhang; Alin Chen; Narendra Chirmule; Shalini Gupta; Arunan Kaliyaperumal; Jason J Pennucci; Juan José Pérez-Ruixo; Steven J Swanson; Marta Starcevic
Immunogenicity of panitumumab in combination chemotherapy clinical trials.
BMC clinical pharmacology 2011;11():17.
2010: Danika Wullner; Lei Zhou; Erica Bramhall; Andrew Kuck; Theresa J Goletz; Steven Swanson; Narendra Chirmule; Vibha Jawa
Considerations for optimization and validation of an in vitro PBMC derived T cell assay for immunogenicity prediction of biotherapeutics.
Clinical immunology (Orlando, Fla.) 2010;137(1):5-14.
2010: Zhandong D Zhong; Steve Dinnogen; Martha Hokom; Chad Ray; David Weinreich; Steven J Swanson; Narendra Chirmule
Identification and inhibition of drug target interference in immunogenicity assays.
Journal of immunological methods 2010;355(1-2):21-8.
2010: Ami C Bautista; Danika Wullner; Mike Moxness; Steven J Swanson; Narendra Chirmule; Vibha Jawa
Impact of matrix-associated soluble factors on the specificity of the immunogenicity assessment.
Bioanalysis 2010;2(4):721-31.
2010: Troy E Barger; Lei Zhou; Michael Hale; Michael Moxness; Steven J Swanson; Narendra Chirmule
Comparing exponentially weighted moving average and run rules in process control of semiquantitative immunogenicity immunoassays.
The AAPS journal 2010;12(1):79-86.
2009: Suzanna Tatarewicz; Michael Moxness; Dohan Weeraratne; Lei Zhou; Michael Hale; Steven J Swanson; Narendra Chirmule
A step-wise approach for transfer of immunogenicity assays during clinical drug development.
The AAPS journal 2009;11(3):526-34.
2009: Steven J Swanson; Narendra Chirmule
Assessing specificity for immunogenicity assays.
Bioanalysis 2009;1(3):611-7.
2007: Lisa S Kierstead; Sheri Dubey; Barbara Meyer; Timothy W Tobery; Robin Mogg; V Rose Fernandez; Romnie Long; Liming Guan; Christine Gaunt; Kelly Collins; Kara J Sykes; Devan V Mehrotra; Narendra Chirmule; John W Shiver; Danilo R Casimiro
Enhanced rates and magnitude of immune responses detected against an HIV vaccine: effect of using an optimized process for isolating PBMC.
AIDS research and human retroviruses 2007;23(1):86-92.
2006: Olivia Hammond; Yue Wang; Tina Green; Joseph Antonello; Robert Kuhn; Clifford Motley; Philip Stump; Beverly Rich; Narendra Chirmule; Rocio D Marchese
The optimization and validation of the glycoprotein ELISA assay for quantitative varicella-zoster virus (VZV) antibody detection.
Journal of medical virology 2006;78(12):1679-87.
2006: Rocio D Marchese; Neil T Jain; Joseph Antonello; Laura Mallette; Kristin L Butterfield-Gerson; Jennifer Raab; Pamela Burke; Cheryl Schulman; Hilary Adgate; Daniel J Sikkema; Narendra Chirmule
Enzyme-linked immunosorbent assay for measuring antibodies to pneumococcal polysaccharides for the PNEUMOVAX 23 vaccine: assay operating characteristics and correlation to the WHO international assay.
Clinical and vaccine immunology : CVI 2006;13(8):905-12.
2006: Sonela A Schlottmann; Neil Jain; Narendra Chirmule; MARK ESSER
A novel chemistry for conjugating pneumococcal polysaccharides to Luminex microspheres.
Journal of immunological methods 2006;309(1-2):75-85.
2005: Dennis Dias; Jeff Van Doren; Sonela A Schlottmann; Sheri Kelly; Derek Puchalski; Wanda Ruiz; Patricia Boerckel; Joseph Kessler; Joseph Antonello; Tina Green; Martha Brown; Judith Smith; Narendra Chirmule; Eliav Barr; Kathrin U Jansen; MARK ESSER
Optimization and validation of a multiplexed luminex assay to quantify antibodies to neutralizing epitopes on human papillomaviruses 6, 11, 16, and 18.
Clinical and diagnostic laboratory immunology 2005;12(8):959-69.
2005: Alexander L Shifrin; Narendra Chirmule; Yi Zhang; Steven E Raper
Macrophage ablation attenuates adenoviral vector-induced pancreatitis.
Surgery 2005;137(5):545-51.
2005: Alexander L Shifrin; Narendra Chirmule; Guang-Ping Gao; James M Wilson; Steven E Raper
Innate immune responses to adenoviral vector-mediated acute pancreatitis.
Pancreas 2005;30(2):122-9.
2004: Narendra Chirmule
Current advances in molecular immunology: reference guide for reviews on molecular vaccines.
Frontiers in bioscience : a journal and virtual library 2004;9():2373-87.
2003: Sarah Bouchard; Tippi C Mackenzie; Antoneta Radu; Satoshi Hayashi; William H Peranteau; Narendra Chirmule; Alan W Flake
Long-term transgene expression in cardiac and skeletal muscle following fetal administration of adenoviral or adeno-associated viral vectors in mice.
The journal of gene medicine 2003;5(11):941-50.
2003: Steven E Raper; Narendra Chirmule; Frank S Lee; Nelson A Wivel; Adam Bagg; Guang-Ping Gao; James M Wilson; Mark L Batshaw
Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer.
Molecular genetics and metabolism 2003;80(1-2):148-58.
2003: MARK ESSER; Rocio D Marchese; Lisa S Kierstead; Lynda Tussey; Fubao Wang; Narendra Chirmule; Michael W Washabaugh
Memory T cells and vaccines.
Vaccine 2003;21(5-6):419-30.
2003: Fubao Wang; Deepa K Patel; Joseph Antonello; Michael W Washabaugh; David C Kaslow; John W Shiver; Narendra Chirmule
Development of an adenovirus-shedding assay for the detection of adenoviral vector-based vaccine and gene therapy products in clinical specimens.
Human gene therapy 2003;14(1):25-36.
2003: David Opalka; Charles E Lachman; Stefani A MacMullen; Kathrin U Jansen; Judith F Smith; Narendra Chirmule; MARK ESSER
Simultaneous quantitation of antibodies to neutralizing epitopes on virus-like particles for human papillomavirus types 6, 11, 16, and 18 by a multiplexed luminex assay.
Clinical and diagnostic laboratory immunology 2003;10(1):108-15.
2002: Maria A Croyle; Narendra Chirmule; Yi Zhang; James M Wilson
PEGylation of E1-deleted adenovirus vectors allows significant gene expression on readministration to liver.
Human gene therapy 2002;13(15):1887-900.
2002: Steven E Raper; Marc Yudkoff; Narendra Chirmule; Guang-Ping Gao; Frederick Nunes; Ziv Haskal; Emma E Furth; Kathleen J Propert; Michael B Robinson; Susan Magosin; Heather Simoes; Lisa Speicher; Joseph Hughes; John Tazelaar; Nelson A Wivel; James M Wilson; Mark L Batshaw
A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency.
Human gene therapy 2002;13(1):163-75.
2001: Markus Hildinger; Alberto Auricchio; Guangping Gao; Liqing Wang; Narendra Chirmule; James M Wilson
Hybrid vectors based on adeno-associated virus serotypes 2 and 5 for muscle-directed gene transfer.
Journal of virology 2001;75(13):6199-203.
2001: Philip W Zoltick; Narendra Chirmule; Michael A Schnell; Guang-Ping Gao; JV Hughes; James M Wilson
Biology of E1-deleted adenovirus vectors in nonhuman primate muscle.
Journal of virology 2001;75(11):5222-9.
2001: Yulong Zhang; Narendra Chirmule; Guang-Ping Gao; R Qian; Maria A Croyle; B Joshi; John Tazelaar; James M Wilson
Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(5 Pt 1):697-707.
2001: Maria A Croyle; Narendra Chirmule; Yulong Zhang; James M Wilson
"Stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung.
Journal of virology 2001;75(10):4792-801.
2001: Laurence Cordier; Guang-Ping Gao; Andrew A Hack; Elizabeth McNally; James M Wilson; Narendra Chirmule; H Lee Sweeney
Muscle-specific promoters may be necessary for adeno-associated virus-mediated gene transfer in the treatment of muscular dystrophies.
Human gene therapy 2001;12(2):205-15.
2000: Guangping Gao; G Qu; M S Burnham; J Huang; Narendra Chirmule; B Joshi; Qian-Chun Yu; J A Marsh; C M Conceicao; James M Wilson
Purification of recombinant adeno-associated virus vectors by column chromatography and its performance in vivo.
Human gene therapy 2000;11(15):2079-91.
2000: Yulong Zhang; Narendra Chirmule; G p Gao; J Wilson
CD40 ligand-dependent activation of cytotoxic T lymphocytes by adeno-associated virus vectors in vivo: role of immature dendritic cells.
Journal of virology 2000;74(17):8003-10.
2000: Rita Sarkar; Guang-Ping Gao; Narendra Chirmule; John Tazelaar; Haig Kazazian
Partial correction of murine hemophilia A with neo-antigenic murine factor VIII.
Human gene therapy 2000;11(6):881-94.
2000: Weidong Xiao; Narendra Chirmule; Michael A Schnell; John Tazelaar; JV Hughes; James M Wilson
Route of administration determines induction of T-cell-independent humoral responses to adeno-associated virus vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(4):323-9.
2000: Narendra Chirmule; Steven E Raper; L Burkly; D Thomas; John Tazelaar; JV Hughes; James M Wilson
Readministration of adenovirus vector in nonhuman primate lungs by blockade of CD40-CD40 ligand interactions.
Journal of virology 2000;74(7):3345-52.
2000: Narendra Chirmule; Weidong Xiao; A Truneh; Michael A Schnell; JV Hughes; Philip W Zoltick; James M Wilson
Humoral immunity to adeno-associated virus type 2 vectors following administration to murine and nonhuman primate muscle.
Journal of virology 2000;74(5):2420-5.
2000: Vibha Anand; Narendra Chirmule; M Fersh; Albert M Maguire; Jean Bennett
Additional transduction events after subretinal readministration of recombinant adeno-associated virus.
Human gene therapy 2000;11(3):449-57.
2000: Narendra Chirmule; John Tazelaar; James M Wilson
Th2-dependent B cell responses in the absence of CD40-CD40 ligand interactions.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(1):248-55.
1999: Jonathan B Zuckerman; C B Robinson; K S McCoy; R Shell; Thomas J Sferra; Narendra Chirmule; Susan Magosin; Kathleen J Propert; E C Brown-Parr; JV Hughes; John Tazelaar; C Baker; M J Goldman; James M Wilson
A phase I study of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator gene to a lung segment of individuals with cystic fibrosis.
Human gene therapy 1999;10(18):2973-85.
1999: Narendra Chirmule; J Moffett; P Dhagat; John Tazelaar; James M Wilson
Adenoviral vector-mediated gene therapy in the mouse lung: no role of Fas-Fas ligand interactions for elimination of transgene expression in bronchioepithelial cells.
Human gene therapy 1999;10(17):2839-46.
1999: Narendra Chirmule; Kathleen J Propert; Susan Magosin; Y Qian; R Qian; J Wilson
Immune responses to adenovirus and adeno-associated virus in humans.
Gene therapy 1999;6(9):1574-83.
1999: Jean Bennett; Albert M Maguire; Artur Vahe Cideciyan; Matthias J Schnell; Ernest Glover; Vibha Anand; Tomas S Aleman; Narendra Chirmule; AR Gupta; Y Huang; Guang-Ping Gao; W C Nyberg; John Tazelaar; J Hughes; James M Wilson; Samuel G Jacobson
Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9920-5.
1999: Narendra Chirmule; Andris Avots; S M LakshmiTamma; Savita Pahwa; Edgar Serfling
CD4-mediated signals induce T cell dysfunction in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(2):644-9.
1999: Narendra Chirmule; A Truneh; S E Haecker; John Tazelaar; G p Gao; Steven E Raper; JV Hughes; James M Wilson
Repeated administration of adenoviral vectors in lungs of human CD4 transgenic mice treated with a nondepleting CD4 antibody.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(1):448-55.
1999: W Xiao; Narendra Chirmule; S C Berta; B McCullough; G Gao; James M Wilson
Gene therapy vectors based on adeno-associated virus type 1.
Journal of virology 1999;73(5):3994-4003.
1999: Narendra Chirmule; A D Moscioni; Y Qian; R Qian; Y Chen; James M Wilson
Fas-Fas ligand interactions play a major role in effector functions of cytotoxic T lymphocytes after adenovirus vector-mediated gene transfer.
Human gene therapy 1999;10(2):259-69.
1998: Narendra Chirmule; JV Hughes; Guang-Ping Gao; Steven E Raper; James M Wilson
Role of E4 in eliciting CD4 T-cell and B-cell responses to adenovirus vectors delivered to murine and nonhuman primate lungs.
Journal of virology 1998;72(7):6138-45.
1997: Steven J McClane; Narendra Chirmule; CV Burke; Steven E Raper
Characterization of the immune response after local delivery of recombinant adenovirus in murine pancreas and successful strategies for readministration.
Human gene therapy 1997;8(18):2207-16.
1997: Seetha M Lakshmi Tamma; Narendra Chirmule; Thomas W McCloskey; Naoki Oyaizu; VS Kalyanaraman; Savita Pahwa
Signals transduced through the CD4 molecule interfere with TCR/CD3-mediated ras activation leading to T cell anergy/apoptosis.
Clinical immunology and immunopathology 1997;85(2):195-201.
1997: Seetha M Lakshmi Tamma; Narendra Chirmule; H Yagura; Naoki Oyaizu; VS Kalyanaraman; Savita Pahwa
CD4 cross-linking (CD4XL) induces RAS activation and tumor necrosis factor-alpha secretion in CD4+ T cells.
Blood 1997;90(4):1588-93.
1997: M Ott; S Emiliani; Carine Van Lint; Georges Herbein; JL Lovett; Narendra Chirmule; Thomas W McCloskey; Savita Pahwa; Eric Verdin
Immune hyperactivation of HIV-1-infected T cells mediated by Tat and the CD28 pathway.
Science (New York, N.Y.) 1997;275(5305):1481-5.
1997: Thomas W McCloskey; M Ott; E Tribble; S A Khan; Saul Teichberg; M O Paul; Savita Pahwa; Eric Verdin; Narendra Chirmule
Dual role of HIV Tat in regulation of apoptosis in T cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(2):1014-9.
1996: Narendra Chirmule; Savita Pahwa
Envelope glycoproteins of human immunodeficiency virus type 1: profound influences on immune functions.
Microbiological reviews 1996;60(2):386-406.
1995: Narendra Chirmule; M Lesser; A Gupta; M Ravipati; Nina Kohn; Savita Pahwa
Immunological characteristics of HIV-infected children: relationship to age, CD4 counts, disease progression, and survival.
AIDS research and human retroviruses 1995;11(10):1209-19.
1995: Pradip N Akolkar; Beena Gulwani-Akolkar; Narendra Chirmule; Savita Pahwa; VS Kalyanaraman; Robert Pergolizzi; S Macphail; Jack Silver
The HIV glycoprotein gp 160 has superantigen-like properties.
Clinical immunology and immunopathology 1995;76(3 Pt 1):255-65.
1995: Narendra Chirmule; H Goonewardena; Savita Pahwa; R Pasieka; VS Kalyanaraman; S Pahwa
HIV-1 envelope glycoproteins induce activation of activated protein-1 in CD4+ T cells.
The Journal of biological chemistry 1995;270(33):19364-9.
1995: Narendra Chirmule; Thomas W McCloskey; R Hu; VS Kalyanaraman; Savita Pahwa
HIV gp120 inhibits T cell activation by interfering with expression of costimulatory molecules CD40 ligand and CD80 (B71).
Journal of immunology (Baltimore, Md. : 1950) 1995;155(2):917-24.
1995: Pradip N Akolkar; Beena Gulwani-Akolkar; Narendra Chirmule; Savita Pahwa; VS Kalyanaraman; Robert Pergolizzi; S Macphail; Jack Silver
V beta-specific activation of T-cells by the HIV glycoprotein gp160.
Annals of the New York Academy of Sciences 1995;756():447-9.
1995: Pradip N Akolkar; Narendra Chirmule; Beena Gulwani-Akolkar; Savita Pahwa; VS Kalyanaraman; Robert Pergolizzi; S Macphail; Jack Silver
V beta-specific activation of T cells by the HIV glycoprotein gp 160.
Scandinavian journal of immunology 1995;41(5):487-98.
1995: Narendra Chirmule; S Than; S A Khan; Savita Pahwa
Human immunodeficiency virus Tat induces functional unresponsiveness in T cells.
Journal of virology 1995;69(1):492-8.
1994: Narendra Chirmule; VS Kalyanaraman; Savita Pahwa
Signals transduced through the CD4 molecule on T lymphocytes activate NF-kappa B.
Biochemical and biophysical research communications 1994;203(1):498-505.
1994: Narendra Chirmule; Naoki Oyaizu; William Saxinger; Savita Pahwa
Nef protein of HIV-1 has B-cell stimulatory activity.
AIDS (London, England) 1994;8(6):733-4.
1994: M Gurram; Narendra Chirmule; X P Wang; N Ponugoti; Savita Pahwa
Increased spontaneous secretion of interleukin 6 and tumor necrosis factor alpha by peripheral blood lymphocytes of human immunodeficiency virus-infected children.
The Pediatric infectious disease journal 1994;13(6):496-501.
1994: X P Wang; M Paul; S Tetali; Elaine J Abrams; Mahrukh Bamji; L Gulick; Narendra Chirmule; Naoki Oyaizu; SS Bakshi; Savita Pahwa
Improved specificity of in vitro anti-HIV antibody production: implications for diagnosis and timing of transmission in infants born to HIV-seropositive mothers.
AIDS research and human retroviruses 1994;10(6):691-9.
1994: Narendra Chirmule; X P Wang; R Hu; Naoki Oyaizu; C Roifman; Rajendra Pahwa; VS Kalyanaraman; Savita Pahwa
Envelope glycoproteins of HIV-1 interfere with T-cell-dependent B cell differentiation: role of CD4-MHC class II interaction in the effector phase of T cell help.
Cellular immunology 1994;155(1):169-82.
1994: Narendra Chirmule; Savita Pahwa
HIV-TAR homology with human c-fes oncogene.
Life sciences 1994;54(18):PL313-4.
1993: Naoki Oyaizu; Thomas W McCloskey; M Coronesi; Narendra Chirmule; VS Kalyanaraman; Savita Pahwa
Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals.
Blood 1993;82(11):3392-400.
1993: Narendra Chirmule; VS Kalyanaraman; S Lederman; Naoki Oyaizu; H Yagura; Michael Yellin; Leonard Chess; Savita Pahwa
HIV-gp 160-induced T cell-dependent B cell differentiation. Role of T cell-B cell activation molecule and IL-6.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(6):2478-86.
1992: Naoki Oyaizu; Narendra Chirmule; H Yagura; Rajendra Pahwa; R A Good; Savita Pahwa
Superantigen staphylococcal enterotoxin B-induced T-helper cell activation is independent of CD4 molecules and phosphatidylinositol hydrolysis.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(17):8035-9.
1992: Naoki Oyaizu; Narendra Chirmule; Savita Pahwa
Role of CD4 molecule in the induction of interleukin 2 and interleukin 2 receptor in class II major histocompatibility complex-restricted antigen-specific T helper clones. T cell receptor/CD3 complex transmits CD4-dependent and CD4-independent signals.
The Journal of clinical investigation 1992;89(6):1807-16.
1992: Narendra Chirmule; Naoki Oyaizu; VS Kalyanaraman; Savita Pahwa
Inhibition of normal B-cell function by human immunodeficiency virus envelope glycoprotein, gp120.
Blood 1992;79(5):1245-54.
1992: Naoki Oyaizu; Narendra Chirmule; Savita Pahwa
Vaccination with gp160 in HIV.
The New England journal of medicine 1992;326(5):347; author reply 348.
1991: Naoki Oyaizu; Narendra Chirmule; Y Ohnishi; VS Kalyanaraman; Savita Pahwa
Human immunodeficiency virus type 1 envelope glycoproteins gp120 and gp160 induce interleukin-6 production in CD4+ T-cell clones.
Journal of virology 1991;65(11):6277-82.
1991: Narendra Chirmule; N Oyaizu; V S Kalyanaraman; Savita Pahwa
Misinterpretation of results of cytokine bioassays.
Journal of immunological methods 1991;137(1):141-4.
1990: Talal A Chatila; E Castigli; Rajendra Pahwa; Savita Pahwa; Narendra Chirmule; Naoki Oyaizu; R A Good; Raif S Geha
Primary combined immunodeficiency resulting from defective transcription of multiple T-cell lymphokine genes.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):10033-7.
1990: Narendra Chirmule; VS Kalyanaraman; H Slade; Naoki Oyaizu; Savita Pahwa
Requirement of the T cell receptor for antigen presentation by T lymphocytes. Effect of envelope glycoproteins of HIV-1 on antigen presentation by T cells.
Clinical and experimental immunology 1990;80(2):161-6.
1990: Naoki Oyaizu; Narendra Chirmule; VS Kalyanaraman; W W Hall; Rajendra Pahwa; M Shuster; Savita Pahwa
Human immunodeficiency virus type 1 envelope glycoprotein gp120 produces immune defects in CD4+ T lymphocytes by inhibiting interleukin 2 mRNA.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(6):2379-83.
1990: Narendra Chirmule; VS Kalyanaraman; William Saxinger; F Wong-Staal; J Ghrayeb; Savita Pahwa
Localization of B-cell stimulatory activity of HIV-1 to the carboxyl terminus of gp41.
AIDS research and human retroviruses 1990;6(3):299-305.
1990: Savita Pahwa; Narendra Chirmule; Naoki Oyaizu
Clinical and immunologic spectrum of HIV infection in infants and children and disease pathogenesis.
Progress in clinical and biological research 1990;325():393-401.
1990: Narendra Chirmule; VS Kalyanaraman; Naoki Oyaizu; H B Slade; Savita Pahwa
Inhibition of functional properties of tetanus antigen-specific T-cell clones by envelope glycoprotein GP120 of human immunodeficiency virus.
Blood 1990;75(1):152-9.
1989: Savita Pahwa; Narendra Chirmule; C Leombruno; W Lim; R Harper; R Bhalla; Rajendra Pahwa; R P Nelson; R A Good
In vitro synthesis of human immunodeficiency virus-specific antibodies in peripheral blood lymphocytes of infants.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(19):7532-6.
1989: Narendra Chirmule; William Saxinger; Savita Pahwa
Influences of related retroviruses on lymphocyte functions.
FEMS microbiology immunology 1989;1(5):271-8.
1988: Narendra Chirmule; VS Kalyanaraman; Naoki Oyaizu; Savita Pahwa
Inhibitory influences of envelope glycoproteins of HIV-1 on normal immune responses.
Journal of acquired immune deficiency syndromes 1988;1(5):425-30.