FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Enzo Alessio

Research Profile

Chemicals & Drugs

Living Beings

Disorders

Procedures

Anatomy

Co-author Network

Publications

TOP 3
Cinzia Spagnul; Roger Alberto; Alberta Bergamo; Stefano Ferrari; Gilles Gasser; Teresa Gianferrara; Vanessa Pierroz; Enzo Alessio
Novel water-soluble (99m)Tc(I)/Re(I)-porphyrin conjugates as potential multimodal agents for molecular imaging.
Ana Rilak; Iztok Turel; Ennio Zangrando; Živadin D Bugarčić; Ioannis Bratsos; Jakob Kljun; Enzo Alessio
Factors that influence the antiproliferative activity of half sandwich Ru(II)-[9]aneS3 coordination compounds: activation kinetics and interaction with guanine derivatives.
Ioannis Bratsos; Teresa Gianferrara; Elisa Mitri; Francesco Ravalico; Ennio Zangrando; Alberta Bergamo; Enzo Alessio
New half sandwich Ru(II) coordination compounds for anticancer activity.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Enzo Alessio (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Cinzia Spagnul; Roger Alberto; Alberta Bergamo; Stefano Ferrari; Gilles Gasser; Teresa Gianferrara; Vanessa Pierroz; Enzo Alessio
Novel water-soluble (99m)Tc(I)/Re(I)-porphyrin conjugates as potential multimodal agents for molecular imaging.
Journal of inorganic biochemistry 2013;122():57-65.
2012: Ana Rilak; Iztok Turel; Ennio Zangrando; Živadin D Bugarčić; Ioannis Bratsos; Jakob Kljun; Enzo Alessio
Factors that influence the antiproliferative activity of half sandwich Ru(II)-[9]aneS3 coordination compounds: activation kinetics and interaction with guanine derivatives.
Dalton transactions (Cambridge, England : 2003) 2012;41(38):11608-18.
2012: Ioannis Bratsos; Teresa Gianferrara; Elisa Mitri; Francesco Ravalico; Ennio Zangrando; Alberta Bergamo; Enzo Alessio
New half sandwich Ru(II) coordination compounds for anticancer activity.
Dalton transactions (Cambridge, England : 2003) 2012;41(24):7358-71.
2012: Enzo Alessio; Massimo Casanova; Ennio Zangrando; Elisabetta Iengo
Modular self-assembled multiporphyrin cages with tunable shape.
Chemical communications (Cambridge, England) 2012;48(42):5112-4.
2011: Ioannis Bratsos; Teresa Gianferrara; Camilla Simonin; Ennio Zangrando; Alberta Bergamo; Enzo Alessio
New half sandwich-type Ru(II) coordination compounds characterized by the fac-Ru(dmso-S)3 fragment: influence of the face-capping group on the chemical behavior and in vitro anticancer activity.
Dalton transactions (Cambridge, England : 2003) 2011;40(37):9533-43.
2011: Ioannis Bratsos; Damijana Urankar; Ennio Zangrando; Petia Genova-Kalou; Janez Košmrlj; Enzo Alessio; Iztok Turel
1-(2-Picolyl)-substituted 1,2,3-triazole as novel chelating ligand for the preparation of ruthenium complexes with potential anticancer activity.
Dalton transactions (Cambridge, England : 2003) 2011;40(19):5188-99.
2011: Elisabetta Iengo; Teresa Gatti; Ennio Zangrando; Maria Teresa Indelli; Franco Scandola; Enzo Alessio
Concerted motions in supramolecular systems: metal-mediated assemblies of porphyrins that behave like nanometric step-machines.
Chemical communications (Cambridge, England) 2011;47(5):1616-8.
2010: Teresa Gianferrara; Alberta Bergamo; Ioannis Bratsos; Barbara Milani; Cinzia Spagnul; Gianni Sava; Enzo Alessio
Ruthenium-porphyrin conjugates with cytotoxic and phototoxic antitumor activity.
Journal of medicinal chemistry 2010;53(12):4678-90.
2009: Teresa Gianferrara; Ioannis Bratsos; Elisabetta Iengo; Barbara Milani; Adrian Ostrić; Cinzia Spagnul; Ennio Zangrando; Enzo Alessio
Synthetic strategies towards ruthenium-porphyrin conjugates for anticancer activity.
Dalton transactions (Cambridge, England : 2003) 2009;(48):10742-56.
2009: Teresa Gianferrara; Ioannis Bratsos; Enzo Alessio
A categorization of metal anticancer compounds based on their mode of action.
Dalton transactions (Cambridge, England : 2003) 2009;(37):7588-98.
2008: Ioannis Bratsos; Stephanie Jedner; Alberta Bergamo; Gianni Sava; Teresa Gianferrara; Ennio Zangrando; Enzo Alessio
Half-sandwich Ru II[9]aneS3 complexes structurally similar to antitumor-active organometallic piano-stool compounds: preparation, structural characterization and in vitro cytotoxic activity.
Journal of inorganic biochemistry 2008;102(5-6):1120-33.
2008: Ioannis Bratsos; Alberta Bergamo; Gianni Sava; Teresa Gianferrara; Ennio Zangrando; Enzo Alessio
Influence of the anionic ligands on the anticancer activity of Ru(II)-dmso complexes: Kinetics of aquation and in vitro cytotoxicity of new dicarboxylate compounds in comparison with their chloride precursors.
Journal of inorganic biochemistry 2008;102(4):606-17.
2007: Sofia Derossi; Massimo Casanova; Elisabetta Iengo; Ennio Zangrando; Mauro Stener; Enzo Alessio
Self-assembled metallacycles with pyrazine edges: a new example in which the unexpected molecular triangle prevails over the expected molecular square.
Inorganic chemistry 2007;46(26):11243-53.
2007: Ioannis Bratsos; Giovanni Birarda; Stephanie Jedner; Ennio Zangrando; Enzo Alessio
Half-sandwich RuII-[9]aneS3 complexes with dicarboxylate ligands: synthesis, characterization and chemical behavior.
Dalton transactions (Cambridge, England : 2003) 2007;(36):4048-58.
2007: Ioannis Bratsos; Barbara Serli; Ennio Zangrando; Nikos Katsaros; Enzo Alessio
Replacement of chlorides with dicarboxylate ligands in anticancer active Ru(II)-DMSO compounds: a new strategy that might lead to improved activity.
Inorganic chemistry 2007;46(3):975-92.
2006: Massimo Casanova; Ennio Zangrando; Fabio Munini; Elisabetta Iengo; Enzo Alessio
fac-[Re(CO)3(dmso-O)3](CF3SO3): a new versatile and efficient Re(I) precursor for the preparation of mono and polynuclear compounds containing fac-[Re(CO)3]+ fragments.
Dalton transactions (Cambridge, England : 2003) 2006;(42):5033-45.
2006: Elisabetta Iengo; Ennio Zangrando; Enzo Alessio
Synthetic strategies and structural aspects of metal-mediated multiporphyrin assemblies.
Accounts of chemical research 2006;39(11):841-51.
2006: Anna Prodi; Claudio Chiorboli; Franco Scandola; Elisabetta Iengo; Enzo Alessio
Electronic energy transfer in a multiporphyrin-based molecular box.
Chemphyschem : a European journal of chemical physics and physical chemistry 2006;7(7):1514-9.
2005: Elisabetta Iengo; Ennio Zangrando; Marco Bellini; Enzo Alessio; Anna Prodi; Claudio Chiorboli; Franco Scandola
Pyridylporphyrin metallacycles with a slipped cofacial geometry: spectroscopic, X-ray, and photophysical characterization.
Inorganic chemistry 2005;44(26):9752-62.
2005: Ioannis Bratsos; Ennio Zangrando; Barbara Serli; Nikos Katsaros; Enzo Alessio
The unprecedented bridging coordination mode of 1,1-cyclobutane dicarboxylate (mu-cbdc-O,O') stabilized by intramolecular hydrogen bonds in ruthenium(II) complexes.
Dalton transactions (Cambridge, England : 2003) 2005;(24):3881-5.
2005: Fabiana Frausin; Vito Scarcia; Moreno Cocchietto; Ariella Furlani; Barbara Serli; Enzo Alessio; Gianni Sava
Free exchange across cells, and echistatin-sensitive membrane target for the metastasis inhibitor NAMI-A (imidazolium trans-imidazole dimethyl sulfoxide tetrachlororuthenate) on KB tumor cells.
The Journal of pharmacology and experimental therapeutics 2005;313(1):227-33.
2005: Anna Prodi; Claudio Chiorboli; Franco Scandola; Elisabetta Iengo; Enzo Alessio; Rainer Dobrawa; Frank Würthner
Wavelength-dependent electron and energy transfer pathways in a side-to-face ruthenium porphyrin/perylene bisimide assembly.
Journal of the American Chemical Society 2005;127(5):1454-62.
2004: Enzo Alessio
Synthesis and reactivity of Ru-, Os-, Rh-, and Ir-halide-sulfoxide complexes.
Chemical reviews 2004;104(9):4203-42.
2004: Aldrik H Velders; Alberta Bergamo; Enzo Alessio; Ennio Zangrando; Jaap G Haasnoot; Claudia Casarsa; Moreno Cocchietto; Sonia Zorzet; Gianni Sava
Synthesis and chemical-pharmacological characterization of the antimetastatic NAMI-A-type Ru(III) complexes (Hdmtp)[trans-RuCl4(dmso-S)(dmtp)], (Na)[trans-RuCl4(dmso-S)(dmtp)], and [mer-RuCl3(H2O)(dmso-S)(dmtp)] (dmtp = 5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidine).
Journal of medicinal chemistry 2004;47(5):1110-21.
2004: Marina Bacac; Anna C G Hotze; Karlijn van der Schilden; Jaap G Haasnoot; Sabrina Pacor; Enzo Alessio; Gianni Sava; Jan Reedijk
The hydrolysis of the anti-cancer ruthenium complex NAMI-A affects its DNA binding and antimetastatic activity: an NMR evaluation.
Journal of inorganic biochemistry 2004;98(2):402-12.
2004: Iztok Turel; Milena Pecanac; Amalija Golobic; Enzo Alessio; Barbara Serli; Alberta Bergamo; Gianni Sava
Solution, solid state and biological characterization of ruthenium(III)-DMSO complexes with purine base derivatives.
Journal of inorganic biochemistry 2004;98(2):393-401.
2004: Alberta Bergamo; Gabriele Stocco; Claudia Casarsa; Moreno Cocchietto; Enzo Alessio; Barbara Serli; Sonia Zorzet; Gianni Sava
Reduction of in vivo lung metastases by dinuclear ruthenium complexes is coupled to inhibition of in vitro tumour invasion.
International journal of oncology 2004;24(2):373-9.
2004: Enzo Alessio; Giovanni Mestroni; Alberta Bergamo; Gianni Sava
Ruthenium antimetastatic agents.
Current topics in medicinal chemistry 2004;4(15):1525-35.
2004: Enzo Alessio; Giovanni Mestroni; Alberta Bergamo; Gianni Sava
Ruthenium anticancer drugs.
Metal ions in biological systems 2004;42():323-51.
2003: Elisabetta Iengo; Ennio Zangrando; Enzo Alessio; Jean-Claude Chambron; Valérie Heitz; Lucia Flamigni; Jean-Pierre Sauvage
A functionalized noncovalent macrocyclic multiporphyrin assembly from a dizinc(II) bis-porphyrin receptor and a free-base dipyridylporphyrin.
Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(23):5879-87.
2003: Alberta Bergamo; Gabriele Stocco; Barbara Gava; Moreno Cocchietto; Enzo Alessio; Barbara Serli; Elisabetta Iengo; Gianni Sava
Distinct effects of dinuclear ruthenium(III) complexes on cell proliferation and on cell cycle regulation in human and murine tumor cell lines.
The Journal of pharmacology and experimental therapeutics 2003;305(2):725-32.
2002: Alberta Bergamo; Barbara Gava; Enzo Alessio; Giovanni Mestroni; Barbara Serli; Moreno Cocchietto; Sonia Zorzet; Gianni Sava
Ruthenium-based NAMI-A type complexes with in vivo selective metastasis reduction and in vitro invasion inhibition unrelated to cell cytotoxicity.
International journal of oncology 2002;21(6):1331-8.
2002: Elisabetta Iengo; Ennio Zangrando; Silvano Geremia; Roland Graff; Bruno Kieffer; Enzo Alessio
Two-point self-coordination of a dizinc(II) bispyridylporphyrin ruthenium complex leading selectively to a discrete molecular assembly: solution and solid-state characterization.
Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(20):4670-4.
2002: Barbara Serli; Ennio Zangrando; Elisabetta Iengo; Giovanni Mestroni; Lesley Yellowlees; Enzo Alessio
Synthesis and structural, spectroscopic, and electrochemical characterization of new ruthenium dimethyl sulfoxide nitrosyls.
Inorganic chemistry 2002;41(15):4033-43.
2002: Elisabetta Iengo; Ennio Zangrando; Romina Minatel; Enzo Alessio
Metallacycles of porphyrins as building blocks in the construction of higher order assemblies through axial coordination of bridging ligands: solution- and solid-state characterization of molecular sandwiches and molecular wires.
Journal of the American Chemical Society 2002;124(6):1003-13.
2002: Gianni Sava; Alberta Bergamo; Sonia Zorzet; Barbara Gava; Claudia Casarsa; Moreno Cocchietto; Ariella Furlani; Vito Scarcia; Barbara Serli; Elisabetta Iengo; Enzo Alessio; Giovanni Mestroni
Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A.
European journal of cancer (Oxford, England : 1990) 2002;38(3):427-35.
2001: Anna Prodi; C J Kleverlaan; Maria Teresa Indelli; Franco Scandola; Enzo Alessio; Elisabetta Iengo
Photophysics of pyridylporphyrin Ru(II) adducts: heavy-atom effects and intramolecular decay pathways.
Inorganic chemistry 2001;40(14):3498-504.
2001: Barbara Serli; Elisabetta Iengo; T Gianferrara; Ennio Zangrando; Enzo Alessio
Novel Unsymmetrical Ru(III) and Mixed-valence Ru(III)/Ru(II) Dinuclear Compounds Related to the Antimetastatic Ru(III) Drug NAMI-A.
Metal-based drugs 2001;8(1):9-18.
2000: Sonia Zorzet; Alberta Bergamo; Moreno Cocchietto; Alenka Sorc; Barbara Gava; Enzo Alessio; Elisabetta Iengo; Gianni Sava
Lack of In vitro cytotoxicity, associated to increased G(2)-M cell fraction and inhibition of matrigel invasion, may predict In vivo-selective antimetastasis activity of ruthenium complexes.
The Journal of pharmacology and experimental therapeutics 2000;295(3):927-33.
2000: Alberta Bergamo; Sonia Zorzet; Barbara Gava; Alenka Sorc; Enzo Alessio; Elisabetta Iengo; Gianni Sava
Effects of NAMI-A and some related ruthenium complexes on cell viability after short exposure of tumor cells.
Anti-cancer drugs 2000;11(8):665-72.
2000: Enzo Alessio; E Ciani; Elisabetta Iengo; V Y Kukushkin; Luigi G Marzilli
Stepwise assembly of unsymmetrical supramolecular arrays containing porphyrins and coordination compounds.
Inorganic chemistry 2000;39(7):1434-43.
2000: Enzo Alessio; Elisabetta Iengo; Sonia Zorzet; Alberta Bergamo; Mauro Coluccia; Angelina Boccarelli; Gianni Sava
Antimetastatic properties and DNA interactions of the novel class of dimeric Ru(III) compounds Na2[[trans-RuCl4(Me2SO)]2(mu-L)] (L = ditopic, non-chelating aromatic N-ligand). A preliminary investigation.
Journal of inorganic biochemistry 2000;79(1-4):173-7.
2000: Enzo Gallori; Cristina Vettori; Enzo Alessio; F G Vilchez; Rosario A Vilaplana; Pierluigi Orioli; Angela Casini; Luigi Messori
DNA as a possible target for antitumor ruthenium(III) complexes.
Archives of biochemistry and biophysics 2000;376(1):156-62.
2000: Luigi Messori; Pierluigi Orioli; D Vullo; Enzo Alessio; Elisabetta Iengo
A spectroscopic study of the reaction of NAMI, a novel ruthenium(III)anti-neoplastic complex, with bovine serum albumin.
European journal of biochemistry / FEBS 2000;267(4):1206-13.
2000: Enzo Alessio; Ennio Zangrando; Elisabetta Iengo; M Macchi; Patricia A Marzilli; Luigi G Marzilli
Understanding the orientation and dynamic motion of planar heterocyclic N-donor ligands by exploiting the symmetry properties of mixed-ligand mu-oxorhenium(V) dinuclear complexes.
Inorganic chemistry 2000;39(2):294-303.
2000: Luigi Messori; F G Vilchez; Rosario A Vilaplana; Francesca Piccioli; Enzo Alessio; B Keppler
Binding of Antitumor Ruthenium(III) Complexes to Plasma Proteins.
Metal-based drugs 2000;7(6):335-42.
2000: Moreno Cocchietto; G Salerno; Enzo Alessio; Giovanni Mestroni; Gianni Sava
Fate of the antimetastatic ruthenium complex ImH [trans-RuCl4(DMSO)Im] after acute i.v. treatment in mice.
Anticancer research 2000;20(1A):197-202.
1999: Alberta Bergamo; R Gagliardi; Vito Scarcia; Ariella Furlani; Enzo Alessio; Giovanni Mestroni; Gianni Sava
In vitro cell cycle arrest, in vivo action on solid metastasizing tumors, and host toxicity of the antimetastatic drug NAMI-A and cisplatin.
The Journal of pharmacology and experimental therapeutics 1999;289(1):559-64.
1999: Gianni Sava; R Gagliardi; Alberta Bergamo; Enzo Alessio; Giovanni Mestroni
Treatment of metastases of solid mouse tumours by NAMI-A: comparison with cisplatin, cyclophosphamide and dacarbazine.
Anticancer research 1999;19(2A):969-72.
1999: Gianni Sava; K Clerici; I Capozzi; Moreno Cocchietto; R Gagliardi; Enzo Alessio; Giovanni Mestroni; Alberto Perbellini
Reduction of lung metastasis by ImH[trans-RuCl4(DMSO)Im]: mechanism of the selective action investigated on mouse tumors.
Anti-cancer drugs 1999;10(1):129-38.
1998: Gianni Sava; I Capozzi; K Clerici; G Gagliardi; Enzo Alessio; Giovanni Mestroni
Pharmacological control of lung metastases of solid tumours by a novel ruthenium complex.
Clinical & experimental metastasis 1998;16(4):371-9.
1998: Gianni Sava; R Gagliardi; Moreno Cocchietto; K Clerici; I Capozzi; M Marrella; Enzo Alessio; Giovanni Mestroni; R Milanino
Comparison of the effects of the antimetastatic compound ImH[trans-RuCl4(DMSO)Im] (NAMI-A) on the arthritic rat and on MCa mammary carcinoma in mice.
Pathology oncology research : POR 1998;4(1):30-6.
1996: Gianni Sava; I Capozzi; Alberta Bergamo; R Gagliardi; Moreno Cocchietto; L Masiero; Maurizio Onisto; Enzo Alessio; Giovanni Mestroni; Spiridione Garbisa
Down-regulation of tumour gelatinase/inhibitor balance and preservation of tumour endothelium by an anti-metastatic ruthenium complex.
International journal of cancer. Journal international du cancer 1996;68(1):60-6.
1996: Alberta Bergamo; Moreno Cocchietto; I Capozzi; Giovanni Mestroni; Enzo Alessio; Gianni Sava
Treatment of residual metastases with Na[trans-RuCl4 (DMSO)lm] and ruthenium uptake by tumor cells.
Anti-cancer drugs 1996;7(6):697-702.
1996: Luigi Messori; Felix Kratz; Enzo Alessio
The Interaction of the Antitumor Complexes Na[trans-RuCl(4) (DMSO)(Im)] and Na[trans-RuCl(4)(DMSO)(Ind)] With Apotransferrin: a Spectroscopic Study.
Metal-based drugs 1996;3(1):1-9.
1995: Gianni Sava; Sabrina Pacor; Alberta Bergamo; Moreno Cocchietto; Giovanni Mestroni; Enzo Alessio
Effects of ruthenium complexes on experimental tumors: irrelevance of cytotoxicity for metastasis inhibition.
Chemico-biological interactions 1995;95(1-2):109-26.
1994: R Gagliardi; Gianni Sava; Sabrina Pacor; Giovanni Mestroni; Enzo Alessio
Antimetastatic action and toxicity on healthy tissues of Na[trans-RuCl4(DMSO)Im] in the mouse.
Clinical & experimental metastasis 1994;12(2):93-100.
1993: Mauro Coluccia; Gianni Sava; F Loseto; A Nassi; Angelina Boccarelli; Domenico Giordano; Enzo Alessio; Giovanni Mestroni
Anti-leukaemic action of RuCl2 (DMSO)4 isomers and prevention of brain involvement on P388 leukaemia and on P388/DDP subline.
European journal of cancer (Oxford, England : 1990) 1993;29A(13):1873-9.
1992: Gianni Sava; Sabrina Pacor; Giovanni Mestroni; Enzo Alessio
Na[trans-RuCl4(DMSO)Im], a metal complex of ruthenium with antimetastatic properties.
Clinical & experimental metastasis 1992;10(4):273-80.
1992: Gianni Sava; Sabrina Pacor; Giovanni Mestroni; Enzo Alessio
Effects of the Ru(III) complexes [mer-RuCl3(DMSO)2Im]degrees and Na[trans-RuCl4(DMSO)Im] on solid mouse tumors.
Anti-cancer drugs 1992;3(1):25-31.
1992: Sabrina Pacor; Gianni Sava; Giovanni Mestroni; Enzo Alessio
Tumor inhibition and effects on host survival time by rutheniumIII and rhodiumIII complexes with dimethylsulphoxide ligands.
Pharmacological research : the official journal of the Italian Pharmacological Society 1992;25 Suppl 1():73-4.
1991: F Loseto; Enzo Alessio; Giovanni Mestroni; G Lacidogna; A Nassi; Domenico Giordano; Mauro Coluccia
Interaction of RuCl2 (dimethylsulphoxide)4 isomers with DNA.
Anticancer research 1991;11(4):1549-53.
1991: Sabrina Pacor; Gianni Sava; V Ceschia; F Bregant; Giovanni Mestroni; Enzo Alessio
Antineoplastic effect of mer-trichlorobisdimethylsulphoxideaminorutheniumIII against murine tumors: comparison with cisplatin and with ImH[RuIm2Cl4].
Chemico-biological interactions 1991;78(2):223-34.
1989: Sabrina Pacor; E Luxich; V Ceschia; Gianni Sava; Enzo Alessio; Giovanni Mestroni
Effects of trans-RuCl2 (DMSO)4 on B16 melanoma in mice.
Pharmacological research : the official journal of the Italian Pharmacological Society 1989;21 Suppl 1():127-8.
1989: Gianni Sava; Sabrina Pacor; Sonia Zorzet; Enzo Alessio; Giovanni Mestroni
Antitumour properties of dimethylsulphoxide ruthenium (II) complexes in the Lewis lung carcinoma system.
Pharmacological research : the official journal of the Italian Pharmacological Society 1989;21(5):617-28.