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Yoon Cho-Chung

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

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Cheadle Chris; Nesterova Maria; Watkins Tonya; Barnes Kathleen C; Hall John C; Rosen Antony; Becker Kevin G; Cho-Chung Yoon S
Regulatory subunits of PKA define an axis of cellular proliferation/differentiation in ovarian cancer cells.
Cheadle Chris; Becker Kevin G; Cho-Chung Yoon S; Nesterova Maria; Watkins Tonya; Wood William; Prabhu Vinayakumar; Barnes Kathleen C
A rapid method for microarray cross platform comparisons using gene expression signatures.
Nesterova Maria V; Johnson Natalie; Cheadle Christopher; Bates Susan E; Mani Sridhar; Stratakis Constantine A; Khan Islam U; Gupta Rishab K; Cho-Chung Yoon S
Autoantibody cancer biomarker: extracellular protein kinase A.

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All Publications

2008: Cheadle Chris; Nesterova Maria; Watkins Tonya; Barnes Kathleen C; Hall John C; Rosen Antony; Becker Kevin G; Cho-Chung Yoon S
Regulatory subunits of PKA define an axis of cellular proliferation/differentiation in ovarian cancer cells.
BMC medical genomics 2008;1():43.
2007: Cheadle Chris; Becker Kevin G; Cho-Chung Yoon S; Nesterova Maria; Watkins Tonya; Wood William; Prabhu Vinayakumar; Barnes Kathleen C
A rapid method for microarray cross platform comparisons using gene expression signatures.
Molecular and cellular probes 2007;21(1):35-46.
2006: Nesterova Maria V; Johnson Natalie; Cheadle Christopher; Bates Susan E; Mani Sridhar; Stratakis Constantine A; Khan Islam U; Gupta Rishab K; Cho-Chung Yoon S
Autoantibody cancer biomarker: extracellular protein kinase A.
Cancer research 2006;66(18):8971-4.
2006: Cho-Chung Yoon S
Autoantibody biomarkers in the detection of cancer.
Biochimica et biophysica acta 2006;1762(6):587-91.
2006: Nesterova M; Johnson N; Cheadle C; Cho-Chung Y S
Autoantibody biomarker opens a new gateway for cancer diagnosis.
Biochimica et biophysica acta 2006;1762(4):398-403.
2006: Pie Jae-Eun; Park Jin-Hee; Park Yoon-Hee; Ryu Yeon-Mi; Kim Ki-Nam; Suh Seung-Woo; Becker Kevin G; Cho-Chung Yoon S; Kim Meyoung-Kon
Effect of genistein on the expression of bone metabolism genes in ovariectomized mice using a cDNA microarray.
The Journal of nutritional biochemistry 2006;17(3):157-64.
2005: Nesterova Maria V; Cho-Chung Yoon S
Chemoprevention with protein kinase A RIalpha antisense in DMBA-mammary carcinogenesis.
Annals of the New York Academy of Sciences 2005;1058():255-64.
2005: Cheadle Chris; Fan Jinshui; Cho-Chung Yoon S; Werner Thomas; Ray Jill; Do Lana; Gorospe Myriam; Becker Kevin G
Stability regulation of mRNA and the control of gene expression.
Annals of the New York Academy of Sciences 2005;1058():196-204.
2005: Cho-Chung Yoon S; Nesterova Maria V
Tumor reversion: protein kinase A isozyme switching.
Annals of the New York Academy of Sciences 2005;1058():76-86.
2005: Nesterova Maria V; Johnson Natalie R; Stewart Trina; Abrams Scott; Cho-Chung Yoon S
CpG immunomer DNA enhances antisense protein kinase A RIalpha inhibition of multidrug-resistant colon carcinoma growth in nude mice: molecular basis for combinatorial therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(16):5950-5.
2005: Cheadle Chris; Fan Jinshui; Cho-Chung Yoon S; Werner Thomas; Ray Jill; Do Lana; Gorospe Myriam; Becker Kevin G
Control of gene expression during T cell activation: alternate regulation of mRNA transcription and mRNA stability.
BMC genomics 2005;6(1):75.
2004: Griffin Kurt J; Kirschner Lawrence S; Matyakhina Ludmila; Stergiopoulos Sotirios; Robinson-White Audrey; Lenherr Sara; Weinberg Frank D; Claflin Edward; Meoli Elise; Cho-Chung Yoon S; Stratakis Constantine A
Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors.
Cancer research 2004;64(24):8811-5.
2004: Griffin K J; Kirschner L S; Matyakhina L; Stergiopoulos S G; Robinson-White A; Lenherr S M; Weinberg F D; Claflin E S; Batista D; Bourdeau I; Voutetakis A; Sandrini F; Meoli E M; Bauer A J; Cho-Chung Y S; Bornstein S R; Carney J A; Stratakis C A
A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A induced lesions.
Journal of medical genetics 2004;41(12):923-31.
2004: Nesterova M; Cho-Chung Y S
Killing the messenger: antisense DNA and siRNA.
Current drug targets 2004;5(8):683-9.
2004: Neary Catherine L; Nesterova Maria; Cho Yee Sook; Cheadle Chris; Becker Kevin G; Cho-Chung Yoon S
Protein kinase A isozyme switching: eliciting differential cAMP signaling and tumor reversion.
Oncogene 2004;23(54):8847-56.
2004: Nesterova Maria V; Cho-Chung Yoon S
Antisense protein kinase A RIalpha inhibits 7,12-dimethylbenz(a)anthracene-induction of mammary cancer: blockade at the initial phase of carcinogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(13):4568-77.
2004: Cho-Chung Yoon S
Antisense protein kinase A RI alpha-induced tumor reversion: portrait of a microarray.
Biochimica et biophysica acta 2004;1697(1-2):71-9.
2003: Mani S; Goel S; Nesterova M; Martin R M; Grindel J M; Rothenberg M L; Zhang R; Tortora G; Cho-Chung Y S
Clinical studies in patients with solid tumors using a second-generation antisense oligonucleotide (GEM 231) targeted against protein kinase A type I.
Annals of the New York Academy of Sciences 2003;1002():252-62.
2003: Cho-Chung Yoon S
CRE-enhancer DNA decoy: a tumor target-based genetic tool.
Annals of the New York Academy of Sciences 2003;1002():124-33.
2003: Kim Young Hoon; Lim Do Sun; Lee Ji Hye; Shim Wan Joo; Ro Young Moo; Park Gil Hong; Becker Kevin G; Cho-Chung Yoon S; Kim Meyoung-Kon
Gene expression profiling of oxidative stress on atrial fibrillation in humans.
Experimental & molecular medicine 2003;35(5):336-49.
2003: Cho-Chung Yoon S; Becker Kevin G
A genome-wide view of antisense.
Nature biotechnology 2003;21(5):492.
2003: Cho-Chung Yoon S
Antisense DNAs as targeted genetic medicine to treat cancer.
Archives of pharmacal research 2003;26(3):183-91.
2003: Cho Yee Sook; Cho-Chung Yoon S
Antisense protein kinase A RIalpha acts synergistically with hydroxycamptothecin to inhibit growth and induce apoptosis in human cancer cells: molecular basis for combinatorial therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):1171-8.
2003: Cheadle Chris; Cho-Chung Yoon S; Becker Kevin G; Vawter Marquis P
Application of z-score transformation to Affymetrix data.
Applied bioinformatics 2003;2(4):209-17.
2003: Cho-Chung Yoon S
cAMP signaling in cancer genesis and treatment.
Cancer treatment and research 2003;115():123-43.
2002: Cho Yee Sook; Kim Meyoung-Kon; Cheadle Chris; Neary Catherine; Park Yun Gyu; Becker Kevin G; Cho-Chung Yoon S
A genomic-scale view of the cAMP response element-enhancer decoy: a tumor target-based genetic tool.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15626-31.
2002: Cho-Chung Yoon S
Antisense DNAs as targeted therapeutics for cancer: no longer a dream.
Current opinion in investigational drugs (London, England : 2000) 2002;3(6):934-9.
2002: Cho-Chung Yoon S; Nesterova Maria; Becker Kevin G; Srivastava Rakesh; Park Yun Gyu; Lee Youl Nam; Cho Yee Sook; Kim Meyoung-Kin; Neary Catherine; Cheadle Chris
Dissecting the circuitry of protein kinase A and cAMP signaling in cancer genesis: antisense, microarray, gene overexpression, and transcription factor decoy.
Annals of the New York Academy of Sciences 2002;968():22-36.
2002: Stratakis Constantine A; Cho-Chung Yoon S
Protein kinase A and human disease.
Trends in endocrinology and metabolism: TEM 2002;13(2):50-2.
2002: Cho Yee Sook; Kim Meyoung-Kon; Tan Langzhu; Srivastava Rakesh; Agrawal Sudhir; Cho-Chung Yoon S
Protein kinase A RIalpha antisense inhibition of PC3M prostate cancer cell growth: Bcl-2 hyperphosphorylation, Bax up-regulation, and Bad-hypophosphorylation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(2):607-14.
2001: Neary C L; Cho-Chung Y S
Nuclear translocation of the catalytic subunit of protein kinase A induced by an antisense oligonucleotide directed against the RIalpha regulatory subunit.
Oncogene 2001;20(55):8019-24.
2001: Cho Y S; Kim M K; Cheadle C; Neary C; Becker K G; Cho-Chung Y S
Antisense DNAs as multisite genomic modulators identified by DNA microarray.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(17):9819-23.
2001: Alper O; Bergmann-Leitner E S; Abrams S; Cho-Chung Y S
Apoptosis, growth arrest and suppression of invasiveness by CRE-decoy oligonucleotide in ovarian cancer cells: protein kinase A downregulation and cytoplasmic export of CRE-binding proteins.
Molecular and cellular biochemistry 2001;218(1-2):55-63.
2000: Nesterova M; Cho-Chung Y S
Oligonucleotide sequence-specific inhibition of gene expression, tumor growth inhibition, and modulation of cAMP signaling by an RNA-DNA hybrid antisense targeted to protein kinase A RIalpha subunit.
Antisense & nucleic acid drug development 2000;10(6):423-33.
2000: Alper O; De Santis M L; Stromberg K; Hacker N F; Cho-Chung Y S; Salomon D S
Anti-sense suppression of epidermal growth factor receptor expression alters cellular proliferation, cell-adhesion and tumorigenicity in ovarian cancer cells.
International journal of cancer. Journal international du cancer 2000;88(4):566-74.
2000: Cho-Chung Y S; Park Y G; Nesterova M; Lee Y N; Cho Y S
CRE-decoy oligonucleotide-inhibition of gene expression and tumor growth.
Molecular and cellular biochemistry 2000;212(1-2):29-34.
2000: Nesterova M; Noguchi K; Park Y G; Lee Y N; Cho-Chung Y S
Compensatory stabilization of RIIbeta protein, cell cycle deregulation, and growth arrest in colon and prostate carcinoma cells by antisense-directed down-regulation of protein kinase A RIalpha protein.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(9):3434-41.
2000: Kirschner L S; Carney J A; Pack S D; Taymans S E; Giatzakis C; Cho Y S; Cho-Chung Y S; Stratakis C A
Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex.
Nature genetics 2000;26(1):89-92.
2000: Lee Y N; Park Y G; Choi Y H; Cho Y S; Cho-Chung Y S
CRE-transcription factor decoy oligonucleotide inhibition of MCF-7 breast cancer cells: cross-talk with p53 signaling pathway.
Biochemistry 2000;39(16):4863-8.
2000: Srivastava R K; Srivastave A R; Cho-Chung Y S
Synergistic effects of 8-Cl-cAMP and retinoic acids in the inhibition of growth and induction of apoptosis in ovarian cancer cells: induction of retinoic acid receptor beta.
Molecular and cellular biochemistry 2000;204(1-2):1-9.
2000: Cho Y S; Park Y G; Lee Y N; Kim M K; Bates S; Tan L; Cho-Chung Y S
Extracellular protein kinase A as a cancer biomarker: its expression by tumor cells and reversal by a myristate-lacking Calpha and RIIbeta subunit overexpression.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(2):835-40.
1999: Cho-Chung Y S; Nesterova M; Pepe S; Lee G R; Noguchi K; Srivastava R K; Srivastava A R; Alper O; Park Y G; Lee Y N
Antisense DNA-targeting protein kinase A-RIA subunit: a novel approach to cancer treatment.
Frontiers in bioscience : a journal and virtual library 1999;4():D898-907.
1999: Alper O; Hacker N F; Cho-Chung Y S
Protein kinase A-Ialpha subunit-directed antisense inhibition of ovarian cancer cell growth: crosstalk with tyrosine kinase signaling pathway.
Oncogene 1999;18(35):4999-5004.
1999: Srivastava R K; Srivastava A R; Cho-Chung Y S; Longo D L
Synergistic effects of retinoic acid and 8-chloro-adenosine 3',5'-cyclic monophosphate on the regulation of retinoic acid receptor beta and apoptosis: involvement of mitochondria.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(7):1892-904.
1999: Cho-Chung Y S; Park Y G; Lee Y N
Oligonucleotides as transcription factor decoys.
Current opinion in molecular therapeutics 1999;1(3):386-92.
1999: Cho-Chung Y S
Antisense oligonucleotide inhibition of serine/threonine kinases: an innovative approach to cancer treatment.
Pharmacology & therapeutics 1999;82(2-3):437-49.
1999: Lee G R; Kim S N; Noguchi K; Park S D; Hong S H; Cho-Chung Y S
Ala99ser mutation in RI alpha regulatory subunit of protein kinase A causes reduced kinase activation by cAMP and arrest of hormone-dependent breast cancer cell growth.
Molecular and cellular biochemistry 1999;195(1-2):77-86.
1999: Srivastava R K; Srivastava A R; Seth P; Agrawal S; Cho-Chung Y S
Growth arrest and induction of apoptosis in breast cancer cells by antisense depletion of protein kinase A-RI alpha subunit: p53-independent mechanism of action.
Molecular and cellular biochemistry 1999;195(1-2):25-36.
1999: Srivastava R K; Srivastava A R; Cho-Chung Y S; Longo D L
Synergistic effects of retinoic acid and 8-Cl-cAMP on apoptosis require caspase-3 activation in human ovarian cancer cells.
Oncogene 1999;18(9):1755-63.
1999: Kondrashin A; Nesterova M; Cho-Chung Y S
Cyclic adenosine 3':5'-monophosphate-dependent protein kinase on the external surface of LS-174T human colon carcinoma cells.
Biochemistry 1999;38(1):172-9.
1999: Park Y G; Nesterova M; Agrawal S; Cho-Chung Y S
Dual blockade of cyclic AMP response element- (CRE) and AP-1-directed transcription by CRE-transcription factor decoy oligonucleotide. gene-specific inhibition of tumor growth.
The Journal of biological chemistry 1999;274(3):1573-80.
1998: Noguchi K; Murata T; Cho-Chung Y S
8-chloroadenosine 3',5'-monophosphate (8-Cl-cAMP) selectively eliminates protein kinase A type I to induce growth inhibition in c-ras-transformed fibroblasts.
European journal of cancer (Oxford, England : 1990) 1998;34(8):1260-7.
1998: Kondrashin A A; Nesterova M V; Cho-Chung Y S
Subcellular distribution of the R-subunits of cAMP-dependent protein kinase in LS-174T human colon carcinoma cells.
Biochemistry and molecular biology international 1998;45(2):237-44.
1998: Srivastava R K; Lee Y N; Noguchi K; Park Y G; Ellis M J; Jeong J S; Kim S N; Cho-Chung Y S
The RIIbeta regulatory subunit of protein kinase A binds to cAMP response element: an alternative cAMP signaling pathway.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):6687-92.
1998: Srivastava R K; Srivastava A R; Korsmeyer S J; Nesterova M; Cho-Chung Y S; Longo D L
Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase.
Molecular and cellular biology 1998;18(6):3509-17.
1998: Srivastava R K; Srivastava A R; Park Y G; Agrawal S; Cho-Chung Y S
Antisense depletion of RIalpha subunit of protein kinase A induces apoptosis and growth arrest in human breast cancer cells.
Breast cancer research and treatment 1998;49(2):97-107.
1998: Cho-Chung Y S
CRE-palindrome oligonucleotide as a transcription factor decoy and an inhibitor of tumor growth.
Antisense & nucleic acid drug development 1998;8(2):167-70.
1998: Srivastava R K; Srivastava A R; Cho-Chung Y S
Synergistic effects of 8-chlorocyclic-AMP and retinoic acid on induction of apoptosis in Ewing's sarcoma CHP-100 cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(3):755-61.
1997: Cho-Chung Y S; Nesterova M; Kondrashin A; Noguchi K; Srivastava R; Pepe S
Antisense-protein kinase A: a single-gene-based therapeutic approach.
Antisense & nucleic acid drug development 1997;7(3):217-23.
1997: Cho-Chung Y S
Antisense DNA toward type I protein kinase A produces sustained inhibition of tumor growth.
Proceedings of the Association of American Physicians 1997;109(1):23-32.
1996: Nesterova M; Yokozaki H; McDuffie E; Cho-Chung Y S
Overexpression of RII beta regulatory subunit of protein kinase A in human colon carcinoma cell induces growth arrest and phenotypic changes that are abolished by site-directed mutation of RII beta.
European journal of biochemistry / FEBS 1996;235(3):486-94.
1996: Cho-Chung Y S
Protein kinase A-directed antisense restrains cancer growth: sequence-specific inhibition of gene expression.
Antisense & nucleic acid drug development 1996;6(3):237-44.
1995: Cho-Chung Y S; Pepe S; Clair T; Budillon A; Nesterova M
cAMP-dependent protein kinase: role in normal and malignant growth.
Critical reviews in oncology/hematology 1995;21(1-3):33-61.
1995: Budillon A; Cereseto A; Kondrashin A; Nesterova M; Merlo G; Clair T; Cho-Chung Y S
Point mutation of the autophosphorylation site or in the nuclear location signal causes protein kinase A RII beta regulatory subunit to lose its ability to revert transformed fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(23):10634-8.
1995: Scala S; Budillon A; Zhan Z; Cho-Chung Y S; Jefferson J; Tsokos M; Bates S E
Downregulation of mdr-1 expression by 8-Cl-cAMP in multidrug resistant MCF-7 human breast cancer cells.
The Journal of clinical investigation 1995;96(2):1026-34.
1995: Nesterova M; Cho-Chung Y S
A single-injection protein kinase A-directed antisense treatment to inhibit tumour growth.
Nature medicine 1995;1(6):528-33.
1994: Tortora G; Pepe S; Bianco C; Damiano V; Ruggiero A; Baldassarre G; Corbo C; Cho-Chung Y S; Bianco A R; Ciardiello F
Differential effects of protein kinase A sub-units on Chinese-hamster-ovary cell cycle and proliferation.
International journal of cancer. Journal international du cancer 1994;59(5):712-6.
1994: Tortora G; Pepe S; Bianco C; Baldassarre G; Budillon A; Clair T; Cho-Chung Y S; Bianco A R; Ciardiello F
The RI alpha subunit of protein kinase A controls serum dependency and entry into cell cycle of human mammary epithelial cells.
Oncogene 1994;9(11):3233-40.
1994: Tortora G; Budillon A; Yokozaki H; Clair T; Pepe S; Merlo G; Rohlff C; Cho-Chung Y S
Retroviral vector-mediated overexpression of the RII beta subunit of the cAMP-dependent protein kinase induces differentiation in human leukemia cells and reverts the transformed phenotype of mouse fibroblasts.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(7):753-9.
1994: Pepe S; Ruggiero A; Tortora G; Ciardiello F; Garbi C; Yokozaki H; Cho-Chung Y S; Clair T; Skalhegg B S; Bianco A R
Flow-cytometric detection of the RI alpha subunit of type I cAMP-dependent protein kinase in human cells.
Cytometry 1994;15(1):73-9.
1993: Cho-Chung Y S; Clair T
The regulatory subunit of cAMP-dependent protein kinase as a target for chemotherapy of cancer and other cellular dysfunctional-related diseases.
Pharmacology & therapeutics 1993;60(2):265-88.
1993: Tortora G; Pepe S; Cirafici A M; Ciardiello F; Porcellini A; Clair T; Colletta G; Cho-Chung Y S; Bianco A R
Thyroid-stimulating hormone-regulated growth and cell cycle distribution of thyroid cells involve type I isozyme of cyclic AMP-dependent protein kinase.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(5):359-65.
1993: Rohlff C; Clair T; Cho-Chung Y S
8-Cl-cAMP induces truncation and down-regulation of the RI alpha subunit and up-regulation of the RII beta subunit of cAMP-dependent protein kinase leading to type II holoenzyme-dependent growth inhibition and differentiation of HL-60 leukemia cells.
The Journal of biological chemistry 1993;268(8):5774-82.
1993: Rohlff C; Safa B; Rahman A; Cho-Chung Y S; Klecker R W; Glazer R I
Reversal of resistance to adriamycin by 8-chloro-cyclic AMP in adriamycin-resistant HL-60 leukemia cells is associated with reduction of type I cyclic AMP-dependent protein kinase and cyclic AMP response element-binding protein DNA-binding activities.
Molecular pharmacology 1993;43(3):372-9.
1993: Yokozaki H; Budillon A; Tortora G; Meissner S; Beaucage S L; Miki K; Cho-Chung Y S
An antisense oligodeoxynucleotide that depletes RI alpha subunit of cyclic AMP-dependent protein kinase induces growth inhibition in human cancer cells.
Cancer research 1993;53(4):868-72.
1992: Pinto A; Aldinucci D; Gattei V; Zagonel V; Tortora G; Budillon A; Cho-Chung Y S
Inhibition of the self-renewal capacity of blast progenitors from acute myeloblastic leukemia patients by site-selective 8-chloroadenosine 3',5'-cyclic monophosphate.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(19):8884-8.
1992: Cho-Chung Y S
Suppression of malignancy targeting cyclic AMP signal transducing proteins.
Biochemical Society transactions 1992;20(2):425-30.
1992: Yokozaki H; Tortora G; Pepe S; Maronde E; Genieser H G; Jastorff B; Cho-Chung Y S
Unhydrolyzable analogues of adenosine 3':5'-monophosphate demonstrating growth inhibition and differentiation in human cancer cells.
Cancer research 1992;52(9):2504-8.
1991: Pepe S; Tortora G; Noguchi P D; Marti G E; Washington G C; Cho-Chung Y S
Effects of 8-chloroadenosine 3',5'-monophosphate and N6-benzyl-cyclic adenosine 5'-monophosphate on cell cycle kinetics of HL-60 leukemia cells.
Cancer research 1991;51(23 Pt 1):6263-7.
1991: Cho-Chung Y S; Nesterova M V; Severin E S; Vinogradov S V
Chemical modification enhances the inhibitory effect of regulatory subunit antisense oligodeoxynucleotide of cAMP-dependent protein kinase type I on cell proliferation.
Biochemistry international 1991;25(4):767-73.
1991: Tortora G; Pepe S; Yokozaki H; Meissner S; Cho-Chung Y S
Cooperative effect of 8-Cl-cAMP and rhGM-CSF on the differentiation of HL-60 human leukemia cells.
Biochemical and biophysical research communications 1991;177(3):1133-40.
1991: Guadagni F; Tortora G; Roselli M; Clair T; Cho-Chung Y S; Schlom J; Greiner J W
Carcinoembryonic antigen regulation in human colorectal tumor cells by a site-selective cyclic AMP analogue: a comparison with interferon-gamma.
International journal of cancer. Journal international du cancer 1991;48(3):413-22.
1991: Tortora G; Yokozaki H; Pepe S; Clair T; Cho-Chung Y S
Differentiation of HL-60 leukemia by type I regulatory subunit antisense oligodeoxynucleotide of cAMP-dependent protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(5):2011-5.
1991: Cho-Chung Y S; Clair T; Tortora G; Yokozaki H; Pepe S
Suppression of malignancy targeting the intracellular signal transducing proteins of cAMP: the use of site-selective cAMP analogs, antisense strategy, and gene transfer.
Life sciences 1991;48(12):1123-32.
1991: Cho-Chung Y S; Clair T; Tortora G; Yokozaki H
Role of site-selective cAMP analogs in the control and reversal of malignancy.
Pharmacology & therapeutics 1991;50(1):1-33.
1990: Cho-Chung Y S
Role of cyclic AMP receptor proteins in growth, differentiation, and suppression of malignancy: new approaches to therapy.
Cancer research 1990;50(22):7093-100.
1990: Tortora G; Cho-Chung Y S
Type II regulatory subunit of protein kinase restores cAMP-dependent transcription in a cAMP-unresponsive cell line.
The Journal of biological chemistry 1990;265(30):18067-70.
1990: Tortora G; Clair T; Cho-Chung Y S
An antisense oligodeoxynucleotide targeted against the type II beta regulatory subunit mRNA of protein kinase inhibits cAMP-induced differentiation in HL-60 leukemia cells without affecting phorbol ester effects.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(2):705-8.
1990: Ciardiello F; Tortora G; Kim N; Clair T; Ally S; Salomon D S; Cho-Chung Y S
8-Chloro-cAMP inhibits transforming growth factor alpha transformation of mammary epithelial cells by restoration of the normal mRNA patterns for cAMP-dependent protein kinase regulatory subunit isoforms which show disruption upon transformation.
The Journal of biological chemistry 1990;265(2):1016-20.
1989: Ally S; Clair T; Katsaros D; Tortora G; Yokozaki H; Finch R A; Avery T L; Cho-Chung Y S
Inhibition of growth and modulation of gene expression in human lung carcinoma in athymic mice by site-selective 8-Cl-cyclic adenosine monophosphate.
Cancer research 1989;49(20):5650-5.
1989: Mednieks M I; Yokozaki H; Merlo G R; Tortora G; Clair T; Ally S; Tahara E; Cho-Chung Y S
Site-selective 8-Cl-cAMP which causes growth inhibition and differentiation increases DNA (CRE)-binding activity in cancer cells.
FEBS letters 1989;254(1-2):83-8.
1989: Cho-Chung Y S
Site-selective 8-chloro-cyclic adenosine 3',5'-monophosphate as a biologic modulator of cancer: restoration of normal control mechanisms.
Journal of the National Cancer Institute 1989;81(13):982-7.
1989: Tortora G; Clair T; Katsaros D; Ally S; Colamonici O; Neckers L M; Tagliaferri P; Jahnsen T; Robins R K; Cho-Chung Y S
Induction of megakaryocytic differentiation and modulation of protein kinase gene expression by site-selective cAMP analogs in K-562 human leukemic cells.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(8):2849-52.
1989: Tortora G; Ciardiello F; Ally S; Clair T; Salomon D S; Cho-Chung Y S
Site-selective 8-chloroadenosine 3',5'-cyclic monophosphate inhibits transformation and transforming growth factor alpha production in Ki-ras-transformed rat fibroblasts.
FEBS letters 1989;242(2):363-7.
1989: Cho-Chung Y S; Clair T; Tagliaferri P; Ally S; Katsaros D; Tortora G; Neckers L; Avery T L; Crabtree G W; Robins R K
Site-selective cyclic AMP analogs as new biological tools in growth control, differentiation, and proto-oncogene regulation.
Cancer investigation 1989;7(2):161-77.
1988: Ally S; Tortora G; Clair T; Grieco D; Merlo G; Katsaros D; Ogreid D; Døskeland S O; Jahnsen T; Cho-Chung Y S
Selective modulation of protein kinase isozymes by the site-selective analog 8-chloroadenosine 3',5'-cyclic monophosphate provides a biological means for control of human colon cancer cell growth.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(17):6319-22.
1988: Katsaros D; Ally S; Cho-Chung Y S
Site-selective cyclic AMP analogues are antagonistic to estrogen stimulation of growth and proto-oncogene expression in human breast-cancer cells.
International journal of cancer. Journal international du cancer 1988;41(6):863-7.
1988: Tagliaferri P; Katsaros D; Clair T; Neckers L; Robins R K; Cho-Chung Y S
Reverse transformation of Harvey murine sarcoma virus-transformed NIH/3T3 cells by site-selective cyclic AMP analogs.
The Journal of biological chemistry 1988;263(1):409-16.
1987: Clair T; Ally S; Tagliaferri P; Robins R K; Cho-Chung Y S
Site-selective cAMP analogs induce nuclear translocation of the RII cAMP receptor protein in Ha-MuSV-transformed NIH/3T3 cells.
FEBS letters 1987;224(2):377-84.
1987: Clair T; Miller W R; Cho-Chung Y S
Prognostic significance of the expression of a ras protein with a molecular weight of 21,000 by human breast cancer.
Cancer research 1987;47(20):5290-3.
1987: Katsaros D; Tortora G; Tagliaferri P; Clair T; Ally S; Neckers L; Robins R K; Cho-Chung Y S
Site-selective cyclic AMP analogs provide a new approach in the control of cancer cell growth.
FEBS letters 1987;223(1):97-103.

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