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Charles Cho

Research Profile

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Publications

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Weijun Shen; Jonathan G Swoboda; Matthew S Tremblay; Weidong Wang; Tom Wu; Xu Wu; You-Qing Zhang; Janine E Baaten; Charles Y Cho; Vishal A Deshmukh; Christophe M Filippi; Richard Glynne; George Harb; Ann E Herman; Qihui Jin; Anwesh Kamireddy; Bryan A Laffitte; Jing Li; Peter McNamara; Peter G Schultz
Small-molecule inducer of β cell proliferation identified by high-throughput screening.
Anna Dubrovska; A Hartung; Venkateshwar A Reddy; Laure C Bouchez; Charles Y Cho; John R Walker; Peter G Schultz
CXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AhR signalling.
Kristen Johnson; Shelly Meeusen; Joshua N Payette; Matthew S Tremblay; Jianing Wang; Xu Wu; Shoutian Zhu; Alana Althage; Laure C Bouchez; Charles Y Cho; Peter G Schultz
A stem cell-based approach to cartilage repair.

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All Publications

2013: Weijun Shen; Jonathan G Swoboda; Matthew S Tremblay; Weidong Wang; Tom Wu; Xu Wu; You-Qing Zhang; Janine E Baaten; Charles Y Cho; Vishal A Deshmukh; Christophe M Filippi; Richard Glynne; George Harb; Ann E Herman; Qihui Jin; Anwesh Kamireddy; Bryan A Laffitte; Jing Li; Peter McNamara; Peter G Schultz
Small-molecule inducer of β cell proliferation identified by high-throughput screening.
Journal of the American Chemical Society 2013;135(5):1669-72.
2012: Anna Dubrovska; A Hartung; Venkateshwar A Reddy; Laure C Bouchez; Charles Y Cho; John R Walker; Peter G Schultz
CXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AhR signalling.
British journal of cancer 2012;107(1):43-52.
2012: Kristen Johnson; Shelly Meeusen; Joshua N Payette; Matthew S Tremblay; Jianing Wang; Xu Wu; Shoutian Zhu; Alana Althage; Laure C Bouchez; Charles Y Cho; Peter G Schultz
A stem cell-based approach to cartilage repair.
Science (New York, N.Y.) 2012;336(6082):717-21.
2012: Anna Dubrovska; Jimmy Elliott; Sumith A Kularatne; Venkateshwar A Reddy; Richard J Salamone; Ihor B Schepotin; Alexander E Stakhovsky; Gennady D Telegeev; Christopher Trussell; Yan Wang; James Watson; Feng Yan; Laure C Bouchez; Charles Y Cho; Peter G Schultz
CXCR4 expression in prostate cancer progenitor cells.
PloS one 2012;7(2):e31226.
2011: Anna Dubrovska; Jimmy Elliott; Vanessa Gorney; Todd Groessl; Chanhyuk Kim; Dong-In Koo; Tun-Hsun Kuo; Chun Li; Teresa Ramirez-Montagut; Weijun Shen; David A Spiegel; Tove tuntland; Xu Wu; Jonathan Chang; Charles Y Cho; Peter G Schultz
A chemically induced vaccine strategy for prostate cancer.
ACS chemical biology 2011;6(11):1223-31.
2011: Jae Wook Lee; Eric C Peters; Peter G Schultz; Xu Wu; Charles Y Cho; Michael Garcia; Rodolfo Gonzalez; Tsuyoshi Hirota; Steve A Kay
A small molecule modulates circadian rhythms through phosphorylation of the period protein.
Angewandte Chemie (International ed. in English) 2011;50(45):10608-11.
2011: Judith Staerk; Lubica Supekova; Shoutian Zhu; Michael Bollong; Laure C Bouchez; Achim Brinker; Bradley D Charette; Charles Y Cho; Ruth K Foreman; Qing Gao; Michael Garcia; Rudolf Jaenisch; Jeffrey Janes; Luke L Lairson; Costas A Lyssiotis; Lea A Medeiro; Peter G Schultz
Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells.
Angewandte Chemie (International ed. in English) 2011;50(25):5734-6.
2011: Tae-gyu Nam; Jongkook Lee; John R Walker; Achim Brinker; Charles Y Cho; Peter G Schultz
Identification and characterization of small-molecule inducers of fetal hemoglobin.
ChemMedChem 2011;6(5):777-80.
2010: Heiko Wurdak; Shoutian Zhu; Kyung Hoon Min; Lindsey Aimone; Luke L Lairson; James Watson; Gregory Chopiuk; James Demas; Bradley Charette; Rajkumar Halder; Eranthie Weerapana; Benjamin F Cravatt; Hollis T Cline; Eric C Peters; Jay Zhang; John R Walker; Chunlei Wu; Jonathan Chang; Tove tuntland; Charles Y Cho; Peter G Schultz
A small molecule accelerates neuronal differentiation in the adult rat.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(38):16542-7.
2010: Rodolfo Gonzalez; Lori L Jennings; Mark Knuth; Anthony P Orth; Heath E Klock; Weija Ou; Julie Feuerhelm; Mitchell V Hull; Eric Koesema; Yuping Wang; Jia Zhang; Chunlei Wu; Charles Y Cho; Andrew I Su; Serge Batalov; Hong Chen; Kristen Johnson; Bryan Laffitte; Deborah G Nguyen; Evan Y Snyder; Peter G Schultz; Jennifer L Harris; Scott A Lesley
Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(8):3552-7.
2009: Costas A Lyssiotis; Ruth K Foreman; Judith Staerk; Michael Garcia; Divya Mathur; Styliani Markoulaki; Jacob Hanna; Luke L Lairson; Bradley D Charette; Laure C Bouchez; Michael Bollong; Conrad Kunick; Achim Brinker; Charles Y Cho; Peter G Schultz; Rudolf Jaenisch
Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(22):8912-7.
2009: Shoutian Zhu; Heiko Wurdak; Jian Wang; Costas A Lyssiotis; Eric C Peters; Charles Y Cho; Xu Wu; Peter G Schultz
A small molecule primes embryonic stem cells for differentiation.
Cell stem cell 2009;4(5):416-26.
2009: Jongkook Lee; Jiyong Hong; Tae-Gyu Nam; Eric C Peters; Anthony P Orth; Bernhard H Geierstanger; Lawrence E Goldfinger; Mark H Ginsberg; Charles Y Cho; Peter G Schultz
A small molecule inhibitor of alpha4 integrin-dependent cell migration.
Bioorganic & medicinal chemistry 2009;17(3):977-80.
2007: Jongkook Lee; Xu Wu; Marina Pasca di Magliano; Eric C Peters; Yan Wang; Jiyong Hong; Metthias Hebrok; Sheng Ding; Charles Y Cho; Peter G Schultz
A small-molecule antagonist of the hedgehog signaling pathway.
Chembiochem : a European journal of chemical biology 2007;8(16):1916-9.
2007: Jiyong Hong; Jongkook Lee; Kyung Hoon Min; John R Walker; Eric C Peters; Nathanael S Gray; Charles Y Cho; Peter G Schultz
Identification and characterization of small-molecule inducers of epidermal keratinocyte differentiation.
ACS chemical biology 2007;2(3):171-5.
2006: Mridul Mukherji; Russell Bell; Lubica Supekova; Yan Wang; Anthony P Orth; Serge Batalov; Loren Miraglia; Dieter Huesken; Joerg Lange; Christopher Martin; Sudhir Sahasrabudhe; Mischa Reinhardt; Francois Natt; Jonathan Hall; Craig Mickanin; Mark Labow; Sumit K Chanda; Charles Y Cho; Peter G Schultz
Genome-wide functional analysis of human cell-cycle regulators.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(40):14819-24.
2006: Charles Y Cho; Seung-Hoi Koo; Yan Wang; Scott Callaway; Susan Hedrick; Puiying A Mak; Anthony P Orth; Eric C Peters; Enrique Saez; Marc Montminy; Peter G Schultz; Sumit K Chanda
Identification of the tyrosine phosphatase PTP-MEG2 as an antagonist of hepatic insulin signaling.
Cell metabolism 2006;3(5):367-78.
2004: Yongqin Wan; Wooyoung Hur; Charles Y Cho; Yi Liu; Francisco J Adrian; Olivier Lozach; Stéphane Bach; Thomas Mayer; Doriano Fabbro; Laurent Meijer; Nathanael S Gray
Synthesis and target identification of hymenialdisine analogs.
Chemistry & biology 2004;11(2):247-59.
2002: Scott A Lesley; Jim Graziano; Charles Y Cho; Mark W Knuth; Heath E Klock
Gene expression response to misfolded protein as a screen for soluble recombinant protein.
Protein engineering 2002;15(2):153-60.