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Hye-Youn Cho

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Hye-Youn Cho; Jennifer Fostel; Wesley Gladwell; Lester Kobzik; Laura Miller-DeGraff; Vijayalakshmi Panduri; Ligon Perrow; Bennett Van Houten; Xuting Wang; Masayuki Yamamoto; Douglas A Bell; Steven R Kleeberger
Targeted deletion of nrf2 impairs lung development and oxidant injury in neonatal mice.
Gillian S Backus; Reuben Howden; Jennifer Fostel; Alison K Bauer; Hye-Youn Cho; Jacqui Marzec; David Peden; Steven R Kleeberger
Protective role of interleukin-10 in ozone-induced pulmonary inflammation.
Hye-Youn Cho; Wesley Gladwell; Xuting Wang; Brian Chorley; Douglas Bell; SEKHAR POTHIREDDY; Steven R Kleeberger
Nrf2-regulated PPAR{gamma} expression is critical to protection against acute lung injury in mice.

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2012: Hye-Youn Cho; Jennifer Fostel; Wesley Gladwell; Lester Kobzik; Laura Miller-DeGraff; Vijayalakshmi Panduri; Ligon Perrow; Bennett Van Houten; Xuting Wang; Masayuki Yamamoto; Douglas A Bell; Steven R Kleeberger
Targeted deletion of nrf2 impairs lung development and oxidant injury in neonatal mice.
Antioxidants & redox signaling 2012;17(8):1066-82.
2010: Gillian S Backus; Reuben Howden; Jennifer Fostel; Alison K Bauer; Hye-Youn Cho; Jacqui Marzec; David Peden; Steven R Kleeberger
Protective role of interleukin-10 in ozone-induced pulmonary inflammation.
Environmental health perspectives 2010;118(12):1721-7.
2010: Hye-Youn Cho; Wesley Gladwell; Xuting Wang; Brian Chorley; Douglas Bell; SEKHAR POTHIREDDY; Steven R Kleeberger
Nrf2-regulated PPAR{gamma} expression is critical to protection against acute lung injury in mice.
American journal of respiratory and critical care medicine 2010;182(2):170-82.
2010: Hye-Youn Cho; Steven R Kleeberger
Nrf2 protects against airway disorders.
Toxicology and applied pharmacology 2010;244(1):43-56.
2009: Hye-Youn Cho; Farhad Imani; Laura Miller-DeGraff; Dianne Walters; Guillermina A Melendi; Masayuki Yamamoto; Fernando P Polack; Steven R Kleeberger
Antiviral activity of Nrf2 in a murine model of respiratory syncytial virus disease.
American journal of respiratory and critical care medicine 2009;179(2):138-50.
2008: Dianne M Walters; Hye-Youn Cho; Steven R Kleeberger
Oxidative stress and antioxidants in the pathogenesis of pulmonary fibrosis: a potential role for Nrf2.
Antioxidants & redox signaling 2008;10(2):321-32.
2008: Steven R Kleeberger; Hye-Youn Cho
Gene-environment interactions in environmental lung diseases.
Novartis Foundation symposium 2008;293():168-78; discussion 178-83.
2007: Hyoung-Kyu Yoon; Hye-Youn Cho; Steven R Kleeberger
Protective role of matrix metalloproteinase-9 in ozone-induced airway inflammation.
Environmental health perspectives 2007;115(11):1557-63.
2007: Narsa Reddy Machireddy; Steven R Kleeberger; Hye-Youn Cho; Masayuki Yamamoto; Thomas W Kensler; Shyam Biswal; SEKHAR POTHIREDDY
Deficiency in Nrf2-GSH signaling impairs type II cell growth and enhances sensitivity to oxidants.
American journal of respiratory cell and molecular biology 2007;37(1):3-8.
2007: Jacqui M Marzec; Jason D Christie; SEKHAR POTHIREDDY; Anne E Jedlicka; Hue Vuong; Paul N Lanken; Richard Aplenc; Tae Yamamoto; Masayuki Yamamoto; Hye-Youn Cho; Steven R Kleeberger
Functional polymorphisms in the transcription factor NRF2 in humans increase the risk of acute lung injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(9):2237-46.
2007: Xuting Wang; Daniel J Tomso; Brian N Chorley; Hye-Youn Cho; Vivian G Cheung; Steven R Kleeberger; Douglas A Bell
Identification of polymorphic antioxidant response elements in the human genome.
Human molecular genetics 2007;16(10):1188-200.
2007: Hye-Youn Cho; Daniel L Morgan; Alison K Bauer; Steven R Kleeberger
Signal transduction pathways of tumor necrosis factor--mediated lung injury induced by ozone in mice.
American journal of respiratory and critical care medicine 2007;175(8):829-39.
2007: Hye-Youn Cho; Steven R Kleeberger
Genetic mechanisms of susceptibility to oxidative lung injury in mice.
Free radical biology & medicine 2007;42(4):433-45.
2006: Hye-Youn Cho; SEKHAR POTHIREDDY; Steven R Kleeberger
Nrf2 defends the lung from oxidative stress.
Antioxidants & redox signaling 2006;8(1-2):76-87.
2006: Srinivas Papaiahgari; Qin Zhang; Steven R Kleeberger; Hye-Youn Cho; SEKHAR POTHIREDDY
Hyperoxia stimulates an Nrf2-ARE transcriptional response via ROS-EGFR-PI3K-Akt/ERK MAP kinase signaling in pulmonary epithelial cells.
Antioxidants & redox signaling 2006;8(1-2):43-52.
2005: Alison K Bauer; Darlene Dixon; Laura M Degraff; Hye-Youn Cho; Christopher R Walker; Alvin M Malkinson; Steven R Kleeberger
Toll-like receptor 4 in butylated hydroxytoluene-induced mouse pulmonary inflammation and tumorigenesis.
Journal of the National Cancer Institute 2005;97(23):1778-81.
2005: Hye-Youn Cho; Anne E Jedlicka; Robert Clarke; Steven R Kleeberger
Role of Toll-like receptor-4 in genetic susceptibility to lung injury induced by residual oil fly ash.
Physiological genomics 2005;22(1):108-17.
2005: Hye-Youn Cho; SEKHAR POTHIREDDY; Andrea Debiase; Masayuki Yamamoto; Steven R Kleeberger
Gene expression profiling of NRF2-mediated protection against oxidative injury.
Free radical biology & medicine 2005;38(3):325-43.
2004: Srinivas Papaiahgari; Steven R Kleeberger; Hye-Youn Cho; Dhan V Kalvakolanu; SEKHAR POTHIREDDY
NADPH oxidase and ERK signaling regulates hyperoxia-induced Nrf2-ARE transcriptional response in pulmonary epithelial cells.
The Journal of biological chemistry 2004;279(40):42302-12.
2004: Hye-Youn Cho; SEKHAR POTHIREDDY; Masayuki Yamamoto; Steven R Kleeberger
The transcription factor NRF2 protects against pulmonary fibrosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(11):1258-60.
2002: Hye-Youn Cho; Anne E Jedlicka; SEKHAR POTHIREDDY; Thomas W Kensler; Masayuki Yamamoto; Liu-Yi Zhang; Steven R Kleeberger
Role of NRF2 in protection against hyperoxic lung injury in mice.
American journal of respiratory cell and molecular biology 2002;26(2):175-82.
2002: Hye-Youn Cho; Anne E Jedlicka; SEKHAR POTHIREDDY; Liu-Yi Zhang; Thomas W Kensler; Steven R Kleeberger
Linkage analysis of susceptibility to hyperoxia. Nrf2 is a candidate gene.
American journal of respiratory cell and molecular biology 2002;26(1):42-51.
2001: Hye-Youn Cho; Liu-Yi Zhang; Steven R Kleeberger
Ozone-induced lung inflammation and hyperreactivity are mediated via tumor necrosis factor-alpha receptors.
American journal of physiology. Lung cellular and molecular physiology 2001;280(3):L537-46.
2001: Steven R Kleeberger; SEKHAR POTHIREDDY; Liu-Yi Zhang; Hye-Youn Cho; Anne E Jedlicka
Toll-like receptor 4 mediates ozone-induced murine lung hyperpermeability via inducible nitric oxide synthase.
American journal of physiology. Lung cellular and molecular physiology 2001;280(2):L326-33.