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Hyun-Kyung Choi

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Hyun-Kyung Choi; Sun Choi; Yoonji Lee; Dong Wook Kang; Hyungchul Ryu; Han-Joo Maeng; Suk-Jae Chung; Vladimir A Pavlyukovets; Larry V Pearce; Attila Toth; Richard Tran; Yun Wang; Matthew A Morgan; Peter M Blumberg; Jeewoo Lee
Non-vanillyl resiniferatoxin analogues as potent and metabolically stable transient receptor potential vanilloid 1 agonists.
Larry V Pearce; Attila Toth; HyungChul Ryu; Dong Wook Kang; Hyun-Kyung Choi; Mi-Kyung Jin; Jeewoo Lee; Peter M Blumberg
Differential modulation of agonist and antagonist structure activity relations for rat TRPV1 by cyclosporin A and other protein phosphatase inhibitors.
Hyungchul Ryu; Mi-Kyung Jin; Su Yeon Kim; Hyun-Kyung Choi; Sang-Uk Kang; Dong Wook Kang; Jeewoo Lee; Larry V Pearce; Vladimir A Pavlyukovets; Matthew A Morgan; Richard Tran; Attila Toth; Daniel J Lundberg; Peter M Blumberg
Stereospecific high-affinity TRPV1 antagonists: chiral N-(2-benzyl-3-pivaloyloxypropyl) 2-[4-(methylsulfonylamino)phenyl]propionamide analogues.

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All Publications

2009: Hyun-Kyung Choi; Sun Choi; Yoonji Lee; Dong Wook Kang; Hyungchul Ryu; Han-Joo Maeng; Suk-Jae Chung; Vladimir A Pavlyukovets; Larry V Pearce; Attila Toth; Richard Tran; Yun Wang; Matthew A Morgan; Peter M Blumberg; Jeewoo Lee
Non-vanillyl resiniferatoxin analogues as potent and metabolically stable transient receptor potential vanilloid 1 agonists.
Bioorganic & medicinal chemistry 2009;17(2):690-8.
2008: Larry V Pearce; Attila Toth; HyungChul Ryu; Dong Wook Kang; Hyun-Kyung Choi; Mi-Kyung Jin; Jeewoo Lee; Peter M Blumberg
Differential modulation of agonist and antagonist structure activity relations for rat TRPV1 by cyclosporin A and other protein phosphatase inhibitors.
Naunyn-Schmiedeberg's archives of pharmacology 2008;377(2):149-57.
2008: Hyungchul Ryu; Mi-Kyung Jin; Su Yeon Kim; Hyun-Kyung Choi; Sang-Uk Kang; Dong Wook Kang; Jeewoo Lee; Larry V Pearce; Vladimir A Pavlyukovets; Matthew A Morgan; Richard Tran; Attila Toth; Daniel J Lundberg; Peter M Blumberg
Stereospecific high-affinity TRPV1 antagonists: chiral N-(2-benzyl-3-pivaloyloxypropyl) 2-[4-(methylsulfonylamino)phenyl]propionamide analogues.
Journal of medicinal chemistry 2008;51(1):57-67.
2007: Jae-Uk Chung; Su Yeon Kim; Ju-Ok Lim; Hyun-Kyung Choi; Sang-Uk Kang; Hae-Seok Yoon; Hyungchul Ryu; Dong Wook Kang; Jeewoo Lee; Bomi Kang; Sun Choi; Attila Toth; Larry V Pearce; Vladimir A Pavlyukovets; Daniel J Lundberg; Peter M Blumberg
Alpha-substituted N-(4-tert-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues as potent and stereospecific TRPV1 antagonists.
Bioorganic & medicinal chemistry 2007;15(18):6043-53.
2006: Jozsef Lazar; Derek C Braun; Attila Tóth; Yun Wang; Larry V Pearce; Vladimir A Pavlyukovets; Peter M Blumberg; Susan H Garfield; Stephen Wincovitch; Hyun-Kyung Choi; Jeewoo Lee
Kinetics of penetration influence the apparent potency of vanilloids on TRPV1.
Molecular pharmacology 2006;69(4):1166-73.
2005: Jeewoo Lee; Sang-Uk Kang; Min-Jung Kil; Myoungyoup Shin; Ju-Ok Lim; Hyun-Kyung Choi; Mi-Kyung Jin; Su Yeon Kim; Sung-Eun Kim; Yong-Sil Lee; Kyung-Hoon Min; Young-Ho Kim; Hee-Jin Ha; Richard Tran; Jacqueline D Welter; Yun Wang; Tamas Szabo; Larry V Pearce; Daniel J Lundberg; Attila Toth; Vladimir A Pavlyukovets; Matthew A Morgan; Peter M Blumberg
Analysis of structure-activity relationships for the 'A-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues as TRPV1 antagonists.
Bioorganic & medicinal chemistry letters 2005;15(18):4136-42.
2005: Jeewoo Lee; Mi-Kyung Jin; Sang-Uk Kang; Su Yeon Kim; Jiyoun Lee; Myoungyoup Shin; Jaemin Hwang; Sookhyun Cho; Yeon-Sil Choi; Hyun-Kyung Choi; Sung-Eun Kim; Young-Ger Suh; Yong-Sil Lee; Young-Ho Kim; Hee-Jin Ha; Attila Toth; Larry V Pearce; Richard Tran; Tamas Szabo; Jacqueline D Welter; Daniel J Lundberg; Yun Wang; Jozsef Lazar; Vladimir A Pavlyukovets; Matthew A Morgan; Peter M Blumberg
Analysis of structure-activity relationships for the 'B-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]-thiourea analogues as TRPV1 antagonists.
Bioorganic & medicinal chemistry letters 2005;15(18):4143-50.
2005: Attila Tóth; Yun Wang; Noemi Kedei; Richard Tran; Larry V Pearce; Sang-Uk Kang; Mi-Kyung Jin; Hyun-Kyung Choi; Jeewoo Lee; Peter M Blumberg
Different vanilloid agonists cause different patterns of calcium response in CHO cells heterologously expressing rat TRPV1.
Life sciences 2005;76(25):2921-32.
2004: Jeewoo Lee; Su Yeon Kim; Jiyoun Lee; Myungshim Kang; Min-Jung Kil; Hyun-Kyung Choi; Mi-Kyung Jin; Yun Wang; Attila Toth; Larry V Pearce; Daniel J Lundberg; Richard Tran; Peter M Blumberg
Analysis of structure-activity relationships with the N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea template for vanilloid receptor 1 antagonism.
Bioorganic & medicinal chemistry 2004;12(13):3411-20.
2004: Jeewoo Lee; Sang-Uk Kang; Hyun-Kyung Choi; Jiyoun Lee; Ju-Ok Lim; Min-Jung Kil; Mi-Kyung Jin; Kang-Pil Kim; Jong-Hyuk Sung; Suk-Jae Chung; Hee-Jin Ha; Young-Ho Kim; Larry V Pearce; Richard Tran; Daniel J Lundberg; Yun Wang; Attila Toth; Peter M Blumberg
Analysis of structure-activity relationships for the 'B-region' of N-(3-acyloxy-2-benzylpropyl)-N(')-[4-(methylsulfonylamino)benzyl]thiourea analogues as vanilloid receptor antagonists: discovery of an N-hydroxythiourea analogue with potent analgesic activity.
Bioorganic & medicinal chemistry letters 2004;14(9):2291-7.
2004: Jeewoo Lee; Su Yeon Kim; Soyoung Park; Ju-Ok Lim; Ji-Min Kim; Myungshim Kang; Jiyoun Lee; Sang-Uk Kang; Hyun-Kyung Choi; Mi-Kyung Jin; Jacqueline D Welter; Tamas Szabo; Richard Tran; Larry V Pearce; Attila Toth; Peter M Blumberg
Structure-activity relationships of simplified resiniferatoxin analogues with potent VR1 agonism elucidates an active conformation of RTX for VR1 binding.
Bioorganic & medicinal chemistry 2004;12(5):1055-69.
2004: Jeewoo Lee; Sang-Uk Kang; Ju-Ok Lim; Hyun-Kyung Choi; Mi-Kyung Jin; Attila Toth; Larry V Pearce; Richard Tran; Yun Wang; Tamas Szabo; Peter M Blumberg
N-[4-(methylsulfonylamino)benzyl]thiourea analogues as vanilloid receptor antagonists: analysis of structure-activity relationships for the "C-Region".
Bioorganic & medicinal chemistry 2004;12(2):371-85.
2003: Jeewoo Lee; Jiyoun Lee; Myungshim Kang; Myoungyoup Shin; Ji-Min Kim; Sang-Uk Kang; Ju-Ok Lim; Hyun-Kyung Choi; Young-Ger Suh; Hyeung-geun Park; Uhtaek Oh; Hee-Doo Kim; Young-Ho Park; Hee-Jin Ha; Young-Ho Kim; Attila Toth; Yun Wang; Richard Tran; Larry V Pearce; Daniel J Lundberg; Peter M Blumberg
N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues: novel potent and high affinity antagonists and partial antagonists of the vanilloid receptor.
Journal of medicinal chemistry 2003;46(14):3116-26.