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Uimook Choi

Research Profile

Chemicals & Drugs

Disorders

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Physiology

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Anatomy

Hematopoietic Stem Cells

Genes & Molecular Sequences

Transgenes

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Publications

TOP 3
Randall K Merling; Timothy G Myers; Francisco Otaizo-Carrasquero; Jason Pan; Colin L Sweeney; Narda L Theobald; Lifeng Chen; Uimook Choi; Suk See De Ravin; Sherry Koontz; Gilda F Linton; Harry L Malech
Transgene-free iPSCs generated from small volume peripheral blood nonmobilized CD34+ cells.
Liang Yi; Uimook Choi; Sherry M Koontz; Qi Liu; Marlene S Orandle; Sara Sadiq-Ali; Fernando J Torres-Velez; Sharon H Jackson
p47(phox) directs murine macrophage cell fate decisions.
Jizhong Zou; Colin L Sweeney; Bin-Kuan Chou; Uimook Choi; Jason Pan; Hongmei Wang; Sarah N Dowey; Linzhao Cheng; Harry L Malech
Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-mediated safe harbor targeting.

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All Publications

2013: Randall K Merling; Timothy G Myers; Francisco Otaizo-Carrasquero; Jason Pan; Colin L Sweeney; Narda L Theobald; Lifeng Chen; Uimook Choi; Suk See De Ravin; Sherry Koontz; Gilda F Linton; Harry L Malech
Transgene-free iPSCs generated from small volume peripheral blood nonmobilized CD34+ cells.
Blood 2013;121(14):e98-107.
2012: Liang Yi; Uimook Choi; Sherry M Koontz; Qi Liu; Marlene S Orandle; Sara Sadiq-Ali; Fernando J Torres-Velez; Sharon H Jackson
p47(phox) directs murine macrophage cell fate decisions.
The American journal of pathology 2012;180(3):1049-58.
2011: Jizhong Zou; Colin L Sweeney; Bin-Kuan Chou; Uimook Choi; Jason Pan; Hongmei Wang; Sarah N Dowey; Linzhao Cheng; Harry L Malech
Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-mediated safe harbor targeting.
Blood 2011;117(21):5561-72.
2011: Giorgia Santilli; Elena Almarza; Christian Brendel; Uimook Choi; Chiara Beilin; Michael P Blundell; Sneha Haria; Kathryn L Parsley; Christine Kinnon; Harry L Malech; Juan A. Bueren; Manuel Grez; Adrian J Thrasher
Biochemical correction of X-CGD by a novel chimeric promoter regulating high levels of transgene expression in myeloid cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(1):122-32.
2010: Elizabeth M Kang; Uimook Choi; Narda Theobald; Gilda F Linton; Debra A Long Priel; Douglas B Kuhns; Harry L Malech
Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils.
Blood 2010;115(4):783-91.
2009: Andre Larochelle; Uimook Choi; Yan Shou; Nora Naumann; Natalia A Loktionova; Joshua R Clevenger; Allen Krouse; Mark Metzger; Robert E Donahue; Elizabeth Kang; Clinton Stewart; Derek Persons; Harry L Malech; Cynthia E Dunbar; Brian P Sorrentino
In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene.
The Journal of clinical investigation 2009;119(7):1952-63.
2007: Nora Naumann; Suk See De Ravin; Uimook Choi; M Moayeri; Narda L Whiting-Theobald; Gilda F Linton; Y Ikeda; H L Malech
Simian immunodeficiency virus lentivector corrects human X-linked chronic granulomatous disease in the NOD/SCID mouse xenograft.
Gene therapy 2007;14(21):1513-24.
2007: Toshinao Kawai; Uimook Choi; Po-Ching Liu; Narda L Whiting-Theobald; Gilda F Linton; Harry L Malech
Diprotin A infusion into nonobese diabetic/severe combined immunodeficiency mice markedly enhances engraftment of human mobilized CD34+ peripheral blood cells.
Stem cells and development 2007;16(3):361-70.
2007: Toshinao Kawai; Uimook Choi; Lanise Cardwell; Suk See DeRavin; Nora Naumann; Narda L Whiting-Theobald; Gilda F Linton; Jaehyun Moon; Philip M Murphy; Harry L Malech
WHIM syndrome myelokathexis reproduced in the NOD/SCID mouse xenotransplant model engrafted with healthy human stem cells transduced with C-terminus-truncated CXCR4.
Blood 2007;109(1):78-84.
2006: Sebastian Brenner; Martin F Ryser; Uimook Choi; Narda L Whiting-Theobald; Eberhard Kuhlisch; Gilda F Linton; Elizabeth Kang; Romy Lehmann; Angela Rosen-Wolff; Andrew G Rudikoff; Ann Farese; Thomas J MacVittie; Joachim Roesler; Mitchell E Horwitz; Harry L Malech
Polyclonal long-term MFGS-gp91phox marking in rhesus macaques after nonmyeloablative transplantation with transduced autologous peripheral blood progenitor cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(2):202-11.
2006: Suk See Ting-De Ravin; Douglas R Kennedy; Nora Naumann; Jeffrey S Kennedy; Uimook Choi; Brian J Hartnett; Gilda F Linton; Narda L Whiting-Theobald; Peter F Moore; William Vernau; Harry L Malech; Peter J Felsburg
Correction of canine X-linked severe combined immunodeficiency by in vivo retroviral gene therapy.
Blood 2006;107(8):3091-7.
2006: Kouhei Yamashita; Mitchell E Horwitz; Akua Kwatemaa; Effie Nomicos; Kathleen Castro; Robert Sokolic; Susan F Foster; Mary Garofalo; Uimook Choi; Mark Ryherd; Margaret R Brown; Susan F Leitman; ALAN WAYNE; Daniel H Fowler; Michael Bishop; Richard W Childs; A John Barrett; Steven Z Pavletic; Harry L Malech
Unique abnormalities of CD4(+) and CD8(+) central memory cells associated with chronic graft-versus-host disease improve after extracorporeal photopheresis.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006;12(1 Suppl 2):22-30.
2005: Toshinao Kawai; Uimook Choi; Narda L Whiting-Theobald; Gilda F Linton; Sebastian Brenner; Joan M G Sechler; Philip M Murphy; Harry L Malech
Enhanced function with decreased internalization of carboxy-terminus truncated CXCR4 responsible for WHIM syndrome.
Experimental hematology 2005;33(4):460-8.
2004: Harry L Malech; Uimook Choi; Sebastian Brenner
Progress toward effective gene therapy for chronic granulomatous disease.
Japanese journal of infectious diseases 2004;57(5):S27-8.
2004: Uimook Choi; Suk See DeRavin; Kouhei Yamashita; Narda L Whiting-Theobald; Gilda F Linton; Natalia A Loktionova; Anthony E Pegg; Harry L Malech
Nuclear-localizing O6-benzylguanine-resistant GFP-MGMT fusion protein as a novel in vivo selection marker.
Experimental hematology 2004;32(8):709-19.
2004: Kouhei Yamashita; Uimook Choi; Patricia C Woltz; Susan F Foster; michael sneller; Frances T Hakim; Daniel H Fowler; Michael Bishop; Steven Z Pavletic; Marisa Tamari; Kathleen Castro; A John Barrett; Richard W Childs; Gabor G Illei; Susan F Leitman; Harry L Malech; Mitchell E Horwitz
Severe chronic graft-versus-host disease is characterized by a preponderance of CD4(+) effector memory cells relative to central memory cells.
Blood 2004;103(10):3986-8.
2004: Sebastian Brenner; Narda L Whiting-Theobald; Toshinao Kawai; Gilda F Linton; Andrew G Rudikoff; Uimook Choi; Martin F Ryser; Philip M Murphy; Joan M G Sechler; Harry L Malech
CXCR4-transgene expression significantly improves marrow engraftment of cultured hematopoietic stem cells.
Stem cells (Dayton, Ohio) 2004;22(7):1128-33.