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Yongmun Choi

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Chemicals & Drugs

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Publications

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Hye-Lin Kim; Younghwa Na; Yongmun Choi; Kyung-Hwa Jeon; Kyu-Yeon Jun; Dae-Kee Kim; Youngjoo Kwon
A-62176, a potent topoisomerase inhibitor, inhibits the expression of human epidermal growth factor receptor 2.
Yongmun Choi; Tae-Gyu Nam
Chemical biology in stem cell research.
Peggy P Hsu; Seong A Kang; Daniel Lim; Jarrod A Marto; Kathleen A Ottina; Timothy R Peterson; Jonathan Rameseder; Yongmun Choi; Nathanael S Gray; Michael B Yaffe; Yi Zhang; David M Sabatini
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.

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2012: Hye-Lin Kim; Younghwa Na; Yongmun Choi; Kyung-Hwa Jeon; Kyu-Yeon Jun; Dae-Kee Kim; Youngjoo Kwon
A-62176, a potent topoisomerase inhibitor, inhibits the expression of human epidermal growth factor receptor 2.
Cancer letters 2012;325(1):72-9.
2012: Yongmun Choi; Tae-Gyu Nam
Chemical biology in stem cell research.
Archives of pharmacal research 2012;35(2):281-97.
2011: Peggy P Hsu; Seong A Kang; Daniel Lim; Jarrod A Marto; Kathleen A Ottina; Timothy R Peterson; Jonathan Rameseder; Yongmun Choi; Nathanael S Gray; Michael B Yaffe; Yi Zhang; David M Sabatini
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.
Science (New York, N.Y.) 2011;332(6035):1317-22.
2010: Xianming Deng; Barun Okram; Qiang Ding; Jianming Zhang; Yongmun Choi; Francisco J Adrián; Amy Wojciechowski; Guobao Zhang; Jianwei Che; Badry Bursulaya; Sandra W Cowan-Jacob; Gabriele Rummel; Taebo Sim; Nathanael S Gray
Expanding the diversity of allosteric bcr-abl inhibitors.
Journal of medicinal chemistry 2010;53(19):6934-46.
2010: Jianming Zhang; Francisco J Adrián; Wolfgang Jahnke; Sandra W Cowan-Jacob; Allen G Li; Roxana E Iacob; Taebo Sim; John Powers; Christine Dierks; Fangxian Sun; Gui-Rong Guo; Qiang Ding; Barun Okram; Yongmun Choi; Amy Wojciechowski; Xianming Deng; Guoxun Liu; Gabriele Fendrich; André Strauss; Navratna Vajpai; Stephan Grzesiek; Tove tuntland; Yi Liu; Badry Bursulaya; Mohammad Azam; Paul W Manley; John R Engen; George Q Daley; Markus Warmuth; Nathanael S Gray
Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors.
Nature 2010;463(7280):501-6.
2009: Yongmun Choi; Markus A Seeliger; Shoghag B Panjarian; Hakjoong Kim; Xianming Deng; Taebo Sim; Brian Couch; Anthony J Koleske; Thomas E Smithgall; Nathanael S Gray
N-myristoylated c-Abl tyrosine kinase localizes to the endoplasmic reticulum upon binding to an allosteric inhibitor.
The Journal of biological chemistry 2009;284(42):29005-14.
2009: Yongmun Choi; Farisa Syeda; John R Walker; Patrick J Finerty; Dominic Cuerrier; Amy Wojciechowski; Qingsong Liu; Sirano Dhe-Paganon; Nathanael S Gray
Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors.
Bioorganic & medicinal chemistry letters 2009;19(15):4467-70.
2006: Dongju Jung; Yongmun Choi; Motonari Uesugi
Small organic molecules that modulate gene transcription.
Drug discovery today 2006;11(9-10):452-7.
2006: Yongmun Choi; Hiroki Shimogawa; Koji Murakami; Latha Ramdas; Wei Zhang; Jun Qin; Motonari Uesugi
Chemical genetic identification of the IGF-linked pathway that is mediated by STAT6 and MFP2.
Chemistry & biology 2006;13(3):241-9.
2004: Youngjoo Kwon; Hans-Dieter Arndt; Qian Mao; Yongmun Choi; Yoshinori Kawazoe; Peter B Dervan; Motonari Uesugi
Small molecule transcription factor mimic.
Journal of the American Chemical Society 2004;126(49):15940-1.
2004: Hiroki Shimogawa; Youngjoo Kwon; Qian Mao; Yoshinori Kawazoe; Yongmun Choi; Shinichi Asada; Hideo Kigoshi; Motonari Uesugi
A wrench-shaped synthetic molecule that modulates a transcription factor-coactivator interaction.
Journal of the American Chemical Society 2004;126(11):3461-71.
2003: Shinichi Asada; Yongmun Choi; Motonari Uesugi
A gene-expression inhibitor that targets an alpha-helix-mediated protein interaction.
Journal of the American Chemical Society 2003;125(17):4992-3.
2003: Yongmun Choi; Yoshinori Kawazoe; Koji Murakami; Hiroyuki Misawa; Motonari Uesugi
Identification of bioactive molecules by adipogenesis profiling of organic compounds.
The Journal of biological chemistry 2003;278(9):7320-4.
2002: Shinichi Asada; Yongmun Choi; Masaki Yamada; Shao-Chun Wang; Mien-Chie Hung; Jun Qin; Motonari Uesugi
External control of Her2 expression and cancer cell growth by targeting a Ras-linked coactivator.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(20):12747-52.