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Yung Hyun Choi

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Ji Hoon Jang; Sang Hyun Kim; Yung Hyun Choi; Tae-Jin Lee; Kyoung-Jin Min; Eun Jung Park; Hee Jung Um; Seon Min Woo; Taeg Kyu Kwon
RU486, a glucocorticoid receptor antagonist, induces apoptosis in U937 human lymphoma cells through reduction in mitochondrial membrane potential and activation of p38 MAPK.
Chang-Hee Kang; Yung Hyun Choi; Yong-Kee Jeong; Wol-Soon Jo; Min Jeong Kim; Kyung-Tae Lee; Min Jeong Seo; Gi-Young Kim
5-Hydroxy-3,6,7,8,3'4'-hexamethoxyflavone inhibits nitric oxide production in lipopolysaccharide-stimulated BV2 microglia via NF-κB suppression and Nrf-2-dependent heme oxygenase-1 induction.
Kyung-Jun Jang; Byung Woo Kim; Gi Young Kim; Hong Ki Kim; You Na Oh; Hyun-Min Yoon; Yoon Ho Chung; Min Ho Han; Hye Jin Hwang; Yung Hyun Choi
Anti-inflammatory effects of saponins derived from the roots of Platycodon grandiflorus in lipopolysaccharide‑stimulated BV2 microglial cells.

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2013: Ji Hoon Jang; Sang Hyun Kim; Yung Hyun Choi; Tae-Jin Lee; Kyoung-Jin Min; Eun Jung Park; Hee Jung Um; Seon Min Woo; Taeg Kyu Kwon
RU486, a glucocorticoid receptor antagonist, induces apoptosis in U937 human lymphoma cells through reduction in mitochondrial membrane potential and activation of p38 MAPK.
Oncology reports 2013;30(1):506-12.
2013: Chang-Hee Kang; Yung Hyun Choi; Yong-Kee Jeong; Wol-Soon Jo; Min Jeong Kim; Kyung-Tae Lee; Min Jeong Seo; Gi-Young Kim
5-Hydroxy-3,6,7,8,3'4'-hexamethoxyflavone inhibits nitric oxide production in lipopolysaccharide-stimulated BV2 microglia via NF-κB suppression and Nrf-2-dependent heme oxygenase-1 induction.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013;57():119-25.
2013: Kyung-Jun Jang; Byung Woo Kim; Gi Young Kim; Hong Ki Kim; You Na Oh; Hyun-Min Yoon; Yoon Ho Chung; Min Ho Han; Hye Jin Hwang; Yung Hyun Choi
Anti-inflammatory effects of saponins derived from the roots of Platycodon grandiflorus in lipopolysaccharide‑stimulated BV2 microglial cells.
International journal of molecular medicine 2013;31(6):1357-66.
2013: Shin-Hyung Park; Young-Chae Chang; Gyoo Yong Chi; Jin Won Hyun; Gi-Young Kim; Wun-Jae Kim; Jun Hyuk Lee; Sung-Kwon Moon; Hyun Soo Park; Yung Hyun Choi
Induction of endoplasmic reticulum stress-mediated apoptosis and non-canonical autophagy by luteolin in NCI-H460 lung carcinoma cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013;56():100-9.
2013: Dong Yeok Shin; Ho Sung Kang; Young Hyun Yoo; Gi-Young Kim; Wun-Jae Kim; Yung Hyun Choi
Decitabine, a DNA methyltransferases inhibitor, induces cell cycle arrest at G2/M phase through p53-independent pathway in human cancer cells.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2013;67(4):305-11.
2013: Cheng-Yun Jin; Gi Young Kim; Wun-Jae Kim; Hongmin Liu; Cheol Park; Hongde Xu; Young Hyun Yoo; Min Ho Han; Su Hyun Hong; Jin-Woo Jeong; Yung Hyun Choi
Synergistic induction of TRAIL-mediated apoptosis by anisomycin in human hepatoma cells via the BH3-only protein Bid and c-Jun/AP-1 signaling pathway.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2013;67(4):321-8.
2013: R G P T Jayasooriya; Bo Yeon Kim; Mun-Ock Kim; Dong-Oh Moon; Sung Gyu Yun; Jong Seog Ahn; Yukihiro Asami; Yung Hyun Choi; Jae-Hyuk Jang; Gi-Young Kim
Verrucarin A enhances TRAIL-induced apoptosis via NF-κB-mediated Fas overexpression.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013;55():1-7.
2013: Hye Young Park; Young Hyun Yoo; Hye Jin Hwang; Gi-Young Kim; Nam Deuk Kim; Taeg Kyu Kwon; Yung Hyun Choi
Apoptosis induction of human leukemia U937 cells by 7,8-dihydroxyflavone hydrate through modulation of the Bcl-2 family of proteins and the MAPKs signaling pathway.
Mutation research 2013;751(2):101-8.
2013: Matharage Gayani Dilshara; Young Pyo Jang; Rajapaksha Gendara Prasad Tharanga Jayasooriya; Joon Bum Jeong; Jin-Woo Jeong; Yong-Kee Jeong; Seungheon Lee; Yong Taek Seo; Yung Hyun Choi; Gi-Young Kim
Water extract of processed Hydrangea macrophylla (Thunb.) Ser. leaf attenuates the expression of pro-inflammatory mediators by suppressing Akt-mediated NF-κB activation.
Environmental toxicology and pharmacology 2013;35(2):311-9.
2013: Hye Hyeon Lee; Cheol Park; Jeong-Uck Park; Min Jeong Seo; Byung Tae Choi; Yung Hyun Choi; Jin-Woo Jeong; Byoung-Won Kang; Gi-Young Kim; Min Jeong Kim; Yong-Kee Jeong
Apoptosis induction of human prostate carcinoma cells by cordycepin through reactive oxygen species‑mediated mitochondrial death pathway.
International journal of oncology 2013;42(3):1036-44.
2013: Chang-Hee Kang; Yung Hyun Choi; Rajapaksha Gendara Prasad Tharanga Jayasooriya; Wun-Jae Kim; Sung-Kwon Moon; Gi-Young Kim
β-Ionone attenuates LPS-induced pro-inflammatory mediators such as NO, PGE2 and TNF-α in BV2 microglial cells via suppression of the NF-κB and MAPK pathway.
Toxicology in vitro : an international journal published in association with BIBRA 2013;27(2):782-7.
2013: Se-Jung Lee; Jung-Hyurk Lim; Seok-Cheol Cho; Yung Hyun Choi; Sangtae Kim; Wun-Jae Kim; Eo-Jin Lee; Soo-Bok Lee; Sung-Kwon Moon
Interleukin-20 promotes migration of bladder cancer cells through extracellular signal-regulated kinase (ERK)-mediated MMP-9 protein expression leading to nuclear factor (NF-κB) activation by inducing the up-regulation of p21(WAF1) protein expression.
The Journal of biological chemistry 2013;288(8):5539-52.
2013: Na Young Jeong; Hye-Jeong Lee; Jee Suk Lee; Soojung Oh; Bong Soo Park; Ki Soo Yoo; Eunok Choe; Yung Hyun Choi; Young Hyun Yoo
Fatty acid synthase inhibitor cerulenin inhibits topoisomerase I catalytic activity and augments SN-38-induced apoptosis.
Apoptosis : an international journal on programmed cell death 2013;18(2):226-37.
2013: Dong-Oh Moon; He Long; Jong Seog Ahn; Yukihiro Asami; Eon Young Bae; Yung Hyun Choi; Jae Hyuk Jang; Chang-Hee Kang; Bo Yeon Kim; Gi-Young Kim
Verrucarin A sensitizes TRAIL-induced apoptosis via the upregulation of DR5 in an eIF2α/CHOP-dependent manner.
Toxicology in vitro : an international journal published in association with BIBRA 2013;27(1):257-63.
2013: Jeong Sook Noh; Yung Hyun Choi; Yeong-Ok Song
Beneficial effects of the active principle component of Korean cabbage kimchi via increasing nitric oxide production and suppressing inflammation in the aorta of apoE knockout mice.
The British journal of nutrition 2013;109(1):17-24.
2013: Ji Yeon Jang; Ha Neui Kim; Yu Ri Kim; Jun Hyuk Lee; Hwa Kyoung Shin; Yung Hyun Choi; Young Whan Choi; Byung Tae Choi
Hexane extract from Polygonum multiflorum attenuates glutamate-induced apoptosis in primary cultured cortical neurons.
Journal of ethnopharmacology 2013;145(1):261-8.
2013: Gi-Young Kim; Wun-Jae Kim; Yung Hyun Choi
Correction: kim, g.-Y. Et Al. Pectenotoxin-2 from marine sponges: a potential anti-cancer agent-a review. Mar. Drugs 2011, 9, 2176-2187.
Marine drugs 2013;11(5):1490-1.
2013: Hyun-Ji Cho; Jung-Yoon Choe; Yung Hyun Choi; Il-Kyung Chung; Jeong-Han Kang; Cheorl-Ho Kim; Wun-Jae Kim; Sung-Kwon Moon; Yong-Suk Moon; Kwan-Kyu Park; Yoon-Yub Park; Hyeun Wook Chang; Young-Chae Chang
Comparative proteome analysis of Tumor necrosis factor α-stimulated human Vascular Smooth Muscle Cells in response to melittin.
Proteome science 2013;11(1):20.
2013: Jin-Woo Jeong; Gi-Young Kim; Won Sup Lee; Sung Chul Shin; Byung Tae Choi; Yung Hyun Choi
Anthocyanins Downregulate Lipopolysaccharide-Induced Inflammatory Responses in BV2 Microglial Cells by Suppressing the NF-κB and Akt/MAPKs Signaling Pathways.
International journal of molecular sciences 2013;14(1):1502-15.
2013: Su Hyun Hong; Gi-Young Kim; Wun-Jae Kim; Sung-Kwon Moon; Young-Chae Chang; Yung Hyun Choi
Bufalin prevents the migration and invasion of T24 bladder carcinoma cells through the inactivation of matrix metalloproteinases and modulation of tight junctions.
International journal of oncology 2013;42(1):277-86.
2013: Eun A Choi; Hye Young Park; Hwa-Seung Yoo; Yung Hyun Choi
Anti-inflammatory effects of egg white combined with chalcanthite in lipopolysaccharide-stimulated BV2 microglia through the inhibition of NF-κB, MAPK and PI3K/Akt signaling pathways.
International journal of molecular medicine 2013;31(1):154-62.
2012: Min Jeong Kim; Hye Hyeon Lee; Jeong-Uck Park; Min Jeong Seo; Woo Hong Joo; Byoung-Won Kang; Gi-Young Kim; Kyoung-Sook Kim; Young-Su Cho; Yung Hyun Choi; Yong-Kee Jeong
Identification of 5-hydroxy-3,6,7,8,3´,4´-hexamethoxyflavone from Hizikia fusiforme involved in the induction of the apoptosis mediators in human AGS carcinoma cells.
Journal of microbiology and biotechnology 2012;22(12):1665-72.
2012: Yung Hyun Choi; Young Hyun Yoo
Taxol-induced growth arrest and apoptosis is associated with the upregulation of the Cdk inhibitor, p21WAF1/CIP1, in human breast cancer cells.
Oncology reports 2012;28(6):2163-9.
2012: Ji-Yeon Jang; Ha-Neui Kim; Yu-Ri Kim; Hwa Kyoung Shin; Yung Hyun Choi; Young-Whan Choi; Jin-Woo Hong; Byung Tae Choi
Hexane extract from Uncaria sinensis exhibits anti-apoptotic properties against glutamate-induced neurotoxicity in primary cultured cortical neurons.
International journal of molecular medicine 2012;30(6):1465-72.
2012: Chang-Hee Kang; Nam Deuk Kim; Yung Hyun Choi; Matharage Gayani Dilshara; Rajapaksha Gendara Prasad Tharanga Jayasooriya; Yong-Kee Jeong; Gi-Young Kim
Caffeine suppresses lipopolysaccharide-stimulated BV2 microglial cells by suppressing Akt-mediated NF-κB activation and ERK phosphorylation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(12):4270-6.
2012: Seetharaman Rajasekar; Yung Hyun Choi; Sun Tae Kim; Cheol Park; Da Jung Park; Sejin Park; Young Hoon Park; Young Whan Choi
In vitro and in vivo anticancer effects of Lithospermum erythrorhizon extract on B16F10 murine melanoma.
Journal of ethnopharmacology 2012;144(2):335-45.
2012: Jee Suk Lee; Sang Yeob Lee; Hwan Tae Park; Chunlan Yan; Yung Hyun Choi; In-Sun Chu; Na Young Jeong; Hye Young Kim; Hyungjong Koh; Young Geol Yoon; Young Hyun Yoo
Expression of αB-crystallin overrides the anti-apoptotic activity of XIAP.
Neuro-oncology 2012;14(11):1332-45.
2012: Seok Joong Yun; Yung Hyun Choi; Pildu Jeong; Isaac Yi Kim; Tae Hwan Kim; Won-Tae Kim; Young-Suk Lee; Sung-Kwon Moon; Phil Hyun Song; Wun-Jae Kim
Cell-free microRNAs in urine as diagnostic and prognostic biomarkers of bladder cancer.
International journal of oncology 2012;41(5):1871-8.
2012: Yun-Jeong Jeong; Cheorl-Ho Kim; Wun-Jae Kim; In-Seon Lee; Sung-Kwon Moon; Kwan-Kyu Park; Key Whang; Hyun-Ji Cho; Jung-Yoon Choe; Yung Hyun Choi; Sang-Mi Han; Hyeun Wook Chang; Young-Chae Chang
Melittin has an inhibitory effect on TNF-α-induced migration of human aortic smooth muscle cells by blocking the MMP-9 expression.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(11):3996-4002.
2012: Hye Jeong Kim; Young-Whan Choi; Min Ho Han; Gi Young Kim; Yung Hyun Choi
Hexane extracts of garlic cloves induce apoptosis through the generation of reactive oxygen species in Hep3B human hepatocarcinoma cells.
Oncology reports 2012;28(5):1757-63.
2012: Eun Young Jang; Chae Ha Yang; Yung Hyun Choi; Min Ho Han; Meeyul Hwang
Sauchinone suppresses lipopolysaccharide-induced inflammatory responses through Akt signaling in BV2 cells.
International immunopharmacology 2012;14(2):188-94.
2012: Yu Jae Hyun; Mei Jing Piao; Rui Zhang; Sungwook Chae; Yung Hyun Choi; Jin Won Hyun
Photo-protection by 3-bromo-4, 5-dihydroxybenzaldehyde against ultraviolet B-induced oxidative stress in human keratinocytes.
Ecotoxicology and environmental safety 2012;83():71-8.
2012: Dong Yeok Shin; Kwangmo Yang; Min Ho Han; Ho Sung Kang; Gi-Young Kim; Wun-Jae Kim; You-Soo Park; Yung Hyun Choi
Decitabine, a DNA methyltransferase inhibitor, induces apoptosis in human leukemia cells through intracellular reactive oxygen species generation.
International journal of oncology 2012;41(3):910-8.
2012: Dong Yeok Shin; Ho Sung Kang; Chan Gil Kim; Gi-Young Kim; Wun-Jae Kim; Yung Hyun Choi
Anti-invasive effects of decitabine, a DNA methyltransferase inhibitor, through tightening of tight junctions and inhibition of matrix metalloproteinase activities in AGS human gastric carcinoma cells.
Oncology reports 2012;28(3):1043-50.
2012: Se-Jung Lee; Jung-Hyurk Lim; Yung Hyun Choi; Wun-Jae Kim; Sung-Kwon Moon
Interleukin-28A triggers wound healing migration of bladder cancer cells via NF-κB-mediated MMP-9 expression inducing the MAPK pathway.
Cellular signalling 2012;24(9):1734-42.
2012: Eun-Jung Kim; Yung Hyun Choi; Yun-Sok Ha; Pildu Jeong; Sung-Kwon Moon; Chunri Yan; Isaac Yi Kim; Wun-Jae Kim
Analysis of hOGG1 genotype as a prognostic marker for muscle invasive bladder cancer: a novel approach using peptide nucleic acid-mediated, real-time PCR clamping.
Urologic oncology 2012;30(5):673-9.
2012: Yun-Sok Ha; Pildu Jeong; Gi-Young Kim; Ji Sang Kim; Tae-Hwan Kim; Sang-Cheol Lee; Sung-Kwon Moon; Isaac Yi Kim; Hyung-Yoon Yoon; Seok-Joong Yun; Yung Hyun Choi; Wun-Jae Kim
Novel combination markers for predicting progression of nonmuscle invasive bladder cancer.
International journal of cancer. Journal international du cancer 2012;131(4):E501-7.
2012: Shin-Hyung Park; Young Hyun Yoo; Young-Chae Chang; Gyoo Yong Chi; Gi-Young Kim; Jeong-Hwan Kim; Wun-Jae Kim; Sung-Kwon Moon; Soo-Wan Nam; Yung Hyun Choi
Induction of apoptosis and autophagy by sodium selenite in A549 human lung carcinoma cells through generation of reactive oxygen species.
Toxicology letters 2012;212(3):252-61.
2012: Min-Ho Jeong; Yung Hyun Choi; Byoung-Won Kang; Gi-Young Kim; Jung-In Kim; Kwang Hyuk Kim; Kyoung-Sook Kim; Jae Yun Lee; Jeong-Uck Park; Min Jeong Seo; Yong-Kee Jeong
Effect of cordycepin purified from Cordyceps militaris on Th1 and Th2 cytokines in mouse splenocytes.
Journal of microbiology and biotechnology 2012;22(8):1161-4.
2012: R G P T Jayasooriya; Chang-Hee Kang; Sang-Hyuck Kang; Weon-Young Chang; Yung Hyun Choi; Jin-Won Hyun; Dong-Oh Moon; Gi-Young Kim
Apigenin decreases cell viability and telomerase activity in human leukemia cell lines.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(8):2605-11.
2012: Hye Young Park; Hye Jin Hwang; Byung-Woo Kim; Gi-Young Kim; Nam Deuk Kim; Wun-Jae Kim; Yung Hyun Choi
Inhibitory effects of diallyl disulfide on the production of inflammatory mediators and cytokines in lipopolysaccharide-activated BV2 microglia.
Toxicology and applied pharmacology 2012;262(2):177-84.
2012: Hye Young Park; Gi-Young Kim; Yung Hyun Choi
Naringenin attenuates the release of pro-inflammatory mediators from lipopolysaccharide-stimulated BV2 microglia by inactivating nuclear factor-κB and inhibiting mitogen-activated protein kinases.
International journal of molecular medicine 2012;30(1):204-10.
2012: Hye Young Park; Young Hyun Yoo; Jin Won Hyun; Chan Gil Kim; Gi-Young Kim; Nam Deuk Kim; Wun-Jae Kim; Yung Hyun Choi
7,8-dihydroxyflavone induces G1 arrest of the cell cycle in U937 human monocytic leukemia cells via induction of the Cdk inhibitor p27 and downregulation of pRB phosphorylation.
Oncology reports 2012;28(1):353-7.
2012: Yun-Sok Ha; Pildu Jeong; Gi-Young Kim; Isaac Yi Kim; Ji Sang Kim; Whi-An Kwon; Sung-Kwon Moon; Seok-Joong Yun; Yung Hyun Choi; Wun-Jae Kim
Tumorigenic and prognostic significance of RASSF1A expression in low-grade (WHO grade 1 and grade 2) nonmuscle-invasive bladder cancer.
Urology 2012;79(6):1411.e1-6.
2012: Hye Young Park; Hye Jin Hwang; Jin Won Hyun; Byung-Woo Kim; Gi-Young Kim; Nam Deuk Kim; Yung Hyun Choi
7,8-Dihydroxyflavone exhibits anti-inflammatory properties by downregulating the NF-κB and MAPK signaling pathways in lipopolysaccharide-treated RAW264.7 cells.
International journal of molecular medicine 2012;29(6):1146-52.
2012: Shin-Hyung Park; Young Hyun Yoo; Gyoo Yong Chi; Hyun Sup Eom; Jin Won Hyun; Gi-Young Kim; Wun-Jae Kim; Su-Jae Lee; Yung Hyun Choi
Role of autophagy in apoptosis induction by methylene chloride extracts of Mori cortex in NCI-H460 human lung carcinoma cells.
International journal of oncology 2012;40(6):1929-40.
2012: Min Ho Han; Hye Jin Hwang; Jin Myung Jung; Gonsup Kim; Gi-Young Kim; Taeg Kyu Kwon; Won Sup Lee; Jing Nan Lu; Chung Ho Ryu; Yung Hyun Choi
Citrus aurantium L. exhibits apoptotic effects on U937 human leukemia cells partly through inhibition of Akt.
International journal of oncology 2012;40(6):2090-6.
2012: Hai Yang Yu; Young-Choon Lee; Hyung-In Moon; Shin-Hyung Park; Yung Hyun Choi; Cheng-Yun Jin; Gi-Young Kim; Kyoung-Sook Kim; Wun-Jae Kim; Jai-Heon Lee
Oleifolioside A mediates caspase-independent human cervical carcinoma HeLa cell apoptosis involving nuclear relocation of mitochondrial apoptogenic factors AIF and EndoG.
Journal of agricultural and food chemistry 2012;60(21):5400-6.
2012: Ji Yeon Jang; Byung Woo Kim; Ha Neui Kim; Yu Ri Kim; Hwa Kyoung Shin; Yung Hyun Choi; Byung Tae Choi
Aqueous fraction from Cuscuta japonica seed suppresses melanin synthesis through inhibition of the p38 mitogen-activated protein kinase signaling pathway in B16F10 cells.
Journal of ethnopharmacology 2012;141(1):338-44.
2012: Mohammad Akbar Hossain; Jung Yoon Jang; Yong Jung Kang; Dong Hwan Kim; Gi-Young Kim; Yung Hyun Choi; Hae Young Chung; Bryan L Copple; Jeon-Ok Moon; Jeong-Hyun Yoon; Nam Deuk Kim
Aspirin enhances doxorubicin-induced apoptosis and reduces tumor growth in human hepatocellular carcinoma cells in vitro and in vivo.
International journal of oncology 2012;40(5):1636-42.
2012: Jin-Woo Jeong; Yong-Kee Jeong; Cheng-Yun Jin; Chan Gil Kim; Gi-Young Kim; Wun-Jae Kim; Jae-Dong Lee; Sung-Kwon Moon; Cheol Park; Min Ho Han; Yung Hyun Choi
Inhibition of migration and invasion of LNCaP human prostate carcinoma cells by cordycepin through inactivation of Akt.
International journal of oncology 2012;40(5):1697-704.
2012: Jun Hee Lim; Kyoung-Jin Min; Eun Jung Park; Bo Ram Seo; Seon Min Woo; Yung Hyun Choi; Taha Iqbal; Ji Hoon Jang; Sang Hyun Kim; Tae-Jin Lee; Taeg Kyu Kwon
Rottlerin induces apoptosis of HT29 colon carcinoma cells through NAG-1 upregulation via an ERK and p38 MAPK-dependent and PKC δ-independent mechanism.
Chemico-biological interactions 2012;197(1):1-7.
2012: Dong-Oh Moon; Sung-Kwon Moon; Mun-Ock Kim; Wun-Jae Kim; Jong Seog Ahn; Yung Hyun Choi; Jae Hyuk Jang; Rajapaksha Gedara Prasad Tharanga Jayasooriya; Chang-Hee Kang; Bo Yeon Kim; Gi-Young Kim
K-RAS transformation in prostate epithelial cell overcomes H2O2-induced apoptosis via upregulation of gamma-glutamyltransferase-2.
Toxicology in vitro : an international journal published in association with BIBRA 2012;26(3):429-34.
2012: Jeong-Seok Park; Dong Yeok Shin; Hwa-Seung Yoo; Chong-Kwan Cho; Gi Young Kim; Wun-Jae Kim; Yeon-Weol Lee; Yung Hyun Choi
Apoptotic and anti-metastatic effects of the whole skin of Venenum bufonis in A549 human lung cancer cells.
International journal of oncology 2012;40(4):1210-9.
2012: Mohammad Akbar Hossain; Jung Yoon Jang; Yong Jung Kang; Dong Hwan Kim; Gi-Young Kim; Yung Hyun Choi; Hae Young Chung; Bryan L Copple; Jeon-Ok Moon; Jeong-Hyun Yoon; Nam Deuk Kim
Aspirin induces apoptosis in vitro and inhibits tumor growth of human hepatocellular carcinoma cells in a nude mouse xenograft model.
International journal of oncology 2012;40(4):1298-304.
2012: Dong-Oh Moon; Young Ree Kim; Young-Sang Koh; Young-Hee Maeng; Weon-Young Chang; Yung Hyun Choi; Jin-Won Hyun; Chang-Hee Kang; Hee-Kyoung Kang; Sang-Hyuck Kang; Gi-Young Kim
Capsaicin sensitizes TRAIL-induced apoptosis through Sp1-mediated DR5 up-regulation: involvement of Ca(2+) influx.
Toxicology and applied pharmacology 2012;259(1):87-95.
2012: Rajapaksha Gedara Prasad Tharanga Jayasooriya; Wun-Jae Kim; Sung-Kwon Moon; Yung Hyun Choi; Gi-Young Kim
Methanol extract of Hydroclathrus clathratus suppresses matrix metalloproteinase-9 in T24 bladder carcinoma cells by suppressing the NF-κB and MAPK pathways.
Oncology reports 2012;27(2):541-6.
2012: Dong Yeok Shin; Young Hyun Yoo; Byung Tae Choi; Gi-Young Kim; Jun Hyuk Lee; Yung Hyun Choi
Apoptosis Induction of Human Prostate Carcinoma DU145 Cells by Diallyl Disulfide via Modulation of JNK and PI3K/AKT Signaling Pathways.
International journal of molecular sciences 2012;13(11):14158-71.
2012: Woo Jin Jeong; Woo Chan Park; Jee Hyun Rho; Sae Heun Rho; Won Yeol Ryu; Seung Hee Yoo; Hee Bae Ahn; Yung Hyun Choi; Na Young Jeong; Hee Seong Yoon; Young Geol Yoon; Young Hyun Yoo
Cytoplasmic and nuclear anti-apoptotic roles of αB-crystallin in retinal pigment epithelial cells.
PloS one 2012;7(9):e45754.
2012: Se-Jung Lee; Seok Joong Yun; Eun-Jong Cha; Young-Hwa Cho; Yung Hyun Choi; Pildu Jeong; Gi-Young Kim; Sangtae Kim; Seon-Kyu Kim; Wun-Jae Kim; Eo-Jin Lee; Sung-Kwon Moon
Identification of pro-inflammatory cytokines associated with muscle invasive bladder cancer; the roles of IL-5, IL-20, and IL-28A.
PloS one 2012;7(9):e40267.
2012: Jeong-Hwan Kim; Soo-Wan Nam; Shin-Hyung Park; Yung Hyun Choi
Gastroprotective effect of selenium on ethanol-induced gastric damage in rats.
International journal of molecular sciences 2012;13(5):5740-50.
2012: Yung Hyun Choi; Hyun Soo Park
Apoptosis induction of U937 human leukemia cells by diallyl trisulfide induces through generation of reactive oxygen species.
Journal of biomedical science 2012;19():50.
2012: Yung Hyun Choi; Hye Young Park
Anti-inflammatory effects of spermidine in lipopolysaccharide-stimulated BV2 microglial cells.
Journal of biomedical science 2012;19():31.
2012: Min Ho Han; Jin Myung Jung; Gonsup Kim; Gi-Young Kim; Wun-Jae Kim; Su-Jae Lee; Won Sup Lee; Jing Nan Lu; Jeong Won Yun; Yung Hyun Choi
Tetraarsenic Hexoxide Induces Beclin-1-Induced Autophagic Cell Death as well as Caspase-Dependent Apoptosis in U937 Human Leukemic Cells.
Evidence-based complementary and alternative medicine : eCAM 2012;2012():201414.
2012: Su-Hyun Hong; Yung Hyun Choi
Bufalin induces apoptosis through activation of both the intrinsic and extrinsic pathways in human bladder cancer cells.
Oncology reports 2012;27(1):114-20.
2011: Dong-Oh Moon; Sung-Yong Park; Jong Seog Ahn; Yung Hyun Choi; Gi-Young Kim
Guggulsterone sensitizes hepatoma cells to TRAIL-induced apoptosis through the induction of CHOP-dependent DR5: involvement of ROS-dependent ER-stress.
Biochemical pharmacology 2011;82(11):1641-50.
2011: Yong Jun Choi; Gi-Young Kim; Wun-Jae Kim; Yeon-Weol Lee; Dong Yeok Shin; Hwa-Seung Yoo; Chong Kwan Cho; Yung Hyun Choi
Inhibition of cell motility and invasion by HangAmDan-B in NCI-H460 human non-small cell lung cancer cells.
Oncology reports 2011;26(6):1601-8.
2011: Rajapaksha Gedara Prasad Tharanga Jayasooriya; Yong-Kee Jeong; Chang-Hee Kang; Yung Hyun Choi; Min-Jeong Seo; Gi-Young Kim
Exopolysaccharide of Laetiporus sulphureus var. miniatus downregulates LPS-induced production of NO, PGE₂, and TNF-α in BV2 microglia cells via suppression of the NF-κB pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2011;49(11):2758-64.
2011: Myung-Hee Cheong; Jin-Woo Jeong; In-Chul Jung; Gi-Young Kim; Wun-Jae Kim; Sang-Ryong Lee; Hwa-Seung Yoo; Yung Hyun Choi
Anti-inflammatory effects of Polygala tenuifolia root through inhibition of NF-κB activation in lipopolysaccharide-induced BV2 microglial cells.
Journal of ethnopharmacology 2011;137(3):1402-8.
2011: Ji Yeon Jang; Ha Neui Kim; Yu Ri Kim; Hwa Kyoung Shin; Woo Young Choi; Yung Hyun Choi; Byung Tae Choi
Partially purified components of Nardostachys chinensis suppress melanin synthesis through ERK and Akt signaling pathway with cAMP down-regulation in B16F10 cells.
Journal of ethnopharmacology 2011;137(3):1207-14.
2011: Cheol Park; Yong-Kee Jeong; Cheng-Yun Jin; Gi-Young Kim; Wun-Jae Kim; Yung Hyun Choi
Induction of apoptosis by ethanol extract of Prunus mume in U937 human leukemia cells through activation of caspases.
Oncology reports 2011;26(4):987-93.
2011: Eun-Sun Yun; Yung Hyun Choi; Wun-Jae Kim; Sung-Suk Park; Ho-Chul Shin; Sung-Kwon Moon
p38 MAPK activation is required for esculetin-induced inhibition of vascular smooth muscle cells proliferation.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(7):1335-42.
2011: Dong-Oh Moon; Yung Hyun Choi; Gi-Young Kim
Role of p21 in SP600125-induced cell cycle arrest, endoreduplication, and apoptosis.
Cellular and molecular life sciences : CMLS 2011;68(19):3249-60.
2011: Won Tae Kim; Sung-Kwon Moon; Seok Joong Yun; Young Deuk Choi; Yung Hyun Choi; Gi-Young Kim; Isaac Yi Kim; Wun-Jae Kim
Prostate size correlates with fasting blood glucose in non-diabetic benign prostatic hyperplasia patients with normal testosterone levels.
Journal of Korean medical science 2011;26(9):1214-8.
2011: Hye-Young Park; Min-Ho Han; Gi-Young Kim; Nam Deuk Kim; Taek-Jeong Nam; Yung Hyun Choi
Inhibitory effects of glycoprotein isolated from Laminaria japonica on lipopolysaccharide-induced pro-inflammatory mediators in BV2 microglial cells.
Journal of food science 2011;76(7):T156-62.
2011: Jeong-Hwan Kim; Wun-Jae Kim; Hyun-Joo Kwon; Soo-Wan Nam; Shin-Hyung Park; Byung-Woo Kim; Yung Hyun Choi
Curcumin stimulates proliferation, stemness acting signals and migration of 3T3-L1 preadipocytes.
International journal of molecular medicine 2011;28(3):429-35.
2011: Hye Young Park; Il-Whan Choi; Min Ho Han; Cheng-Yun Jin; Gi-Young Kim; Nam Deuk Kim; Taeg Kyu Kwon; Taek-Jeong Nam; Cheol Park; Yung Hyun Choi
Anti-inflammatory effects of fucoidan through inhibition of NF-κB, MAPK and Akt activation in lipopolysaccharide-induced BV2 microglia cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2011;49(8):1745-52.
2011: Won Sik Yeo; Yung Hyun Choi; Byoung-Won Kang; Min Jeong Kim; Hye Hyeon Lee; Jeong-Uck Park; Min Jeong Seo; Yong-Kee Jeong
Biochemical analysis of a fibrinolytic enzyme purified from Bacillus subtilis strain A1.
Journal of microbiology (Seoul, Korea) 2011;49(3):376-80.
2011: Na Young Jeong; Young Geol Yoon; Jee Hyun Rho; Jee Suk Lee; Sang Yeob Lee; Ki S Yoo; Suhee Song; Hongsuk Suh; Yung Hyun Choi; Young Hyun Yoo
The novel resveratrol analog HS-1793-induced polyploid LNCaP prostate cancer cells are vulnerable to downregulation of Bcl-xL.
International journal of oncology 2011;38(6):1597-604.
2011: Cheol Park; Gi-Young Kim; Jee Hyung Jung; Wun-Jae Kim; Yung Hyun Choi
Pectenotoxin-2 induces G1 arrest of the cell cycle in synovial fibroblasts of patients with rheumatoid arthritis.
International journal of molecular medicine 2011;27(6):783-7.
2011: Jin-Woo Jeong; Cheng-Yun Jin; Cheol Park; Su Hyun Hong; Gi-Young Kim; Yong Kee Jeong; Jae-Dong Lee; Young Hyun Yoo; Yung Hyun Choi
Induction of apoptosis by cordycepin via reactive oxygen species generation in human leukemia cells.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(4):817-24.
2011: Hyun Soo Park; Il-Whan Choi; Young-Whan Choi; Hye Jin Hwang; Gi-Young Kim; Nam Deuk Kim; Yung Hyun Choi
Inhibition of matrix metalloproteinase activities and tightening of tight junctions by diallyl disulfide in AGS human gastric carcinoma cells.
Journal of food science 2011;76(4):T105-11.
2011: Wun-Jae Kim; Sung-Kwon Moon; Hong-Duck Um; Seok-Joong Yun; In-Chang Cho; Pildu Jeong; Isaac Yi Kim; Seon-Kyu Kim; Yung Hyun Choi
A four-gene signature predicts disease progression in muscle invasive bladder cancer.
Molecular medicine (Cambridge, Mass.) 2011;17(5-6):478-85.
2011: Yung Hyun Choi; U Lee; J H Suh; Y G Kim; M Lee; E Oh; M G Lee
Pharmacokinetic interaction between ϵ-acetamidocaproic acid (AACA) and cimetidine in indomethacin-induced acute gastric ulcer and control rats: inhibition of active renal secretion of AACA by cimetidine.
Xenobiotica; the fate of foreign compounds in biological systems 2011;41(5):409-15.
2011: Min Jung Choi; Eun Jung Park; Jung Hwa Oh; Kyoung-Jin Min; Eun Sun Yang; Young Ho Kim; Tae Jin Lee; Sang Hyun Kim; Yung Hyun Choi; Jong-Wook Park; Taeg Kyu Kwon
Cafestol, a coffee-specific diterpene, induces apoptosis in renal carcinoma Caki cells through down-regulation of anti-apoptotic proteins and Akt phosphorylation.
Chemico-biological interactions 2011;190(2-3):102-8.
2011: Min-Jung Kim; Soo-Jung Woo; Chang-Hwan Yoon; Jae-Seong Lee; Sungkwan An; Yung Hyun Choi; Sang-Gu Hwang; Gyesoon Yoon; Su-Jae Lee
Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation.
The Journal of biological chemistry 2011;286(15):12924-32.
2011: Dong-Oh Moon; Yung Hyun Choi; Sung-Kwon Moon; Wun-Jae Kim; Gi-Young Kim
Gossypol decreases tumor necrosis factor-α-induced intercellular adhesion molecule-1 expression via suppression of NF-κB activity.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2011;49(4):999-1005.
2011: Chang-Hee Kang; Dong-Oh Moon; Yung Hyun Choi; Il-Whan Choi; Sung-Kwon Moon; Wun-Jae Kim; Gi-Young Kim
Piceatannol enhances TRAIL-induced apoptosis in human leukemia THP-1 cells through Sp1- and ERK-dependent DR5 up-regulation.
Toxicology in vitro : an international journal published in association with BIBRA 2011;25(3):605-12.
2011: Min-Su Yim; Yun-Sok Ha; Isaac Yi Kim; Seok-Joong Yun; Yung Hyun Choi; Wun-Jae Kim
HMOX1 is an important prognostic indicator of nonmuscle invasive bladder cancer recurrence and progression.
The Journal of urology 2011;185(2):701-5.
2011: Dong Yeok Shin; Jing Nan Lu; Gi-Young Kim; Jin Myung Jung; Ho Sung Kang; Won Sup Lee; Yung Hyun Choi
Anti-invasive activities of anthocyanins through modulation of tight junctions and suppression of matrix metalloproteinase activities in HCT-116 human colon carcinoma cells.
Oncology reports 2011;25(2):567-72.
2011: Min Ho Han; Gi Young Kim; Sung-Kwon Moon; Wun-Jae Kim; Taek-Jeong Nam; Yung Hyun Choi
Apoptosis induction by glycoprotein isolated from Laminaria japonica is associated with down-regulation of telomerase activity and prostaglandin E2 synthesis in AGS human gastric cancer cells.
International journal of oncology 2011;38(2):577-84.
2011: Cheng-Yun Jin; Cheol Park; Hye Jin Hwang; Gi-Young Kim; Byung Tae Choi; Wun-Jae Kim; Yung Hyun Choi
Naringenin up-regulates the expression of death receptor 5 and enhances TRAIL-induced apoptosis in human lung cancer A549 cells.
Molecular nutrition & food research 2011;55(2):300-9.
2011: Sung-Suk Park; Sung-Kyu Park; Jung-Hyurk Lim; Yung Hyun Choi; Wun-Jae Kim; Sung-Kwon Moon
Esculetin inhibits cell proliferation through the Ras/ERK1/2 pathway in human colon cancer cells.
Oncology reports 2011;25(1):223-30.
2011: Yun-Sok Ha; Chunri Yan; Cheol Park; Seok-Joong Yun; Sung-Kwon Moon; Yung Hyun Choi; Wun-Jae Kim
GSTT1: a marker of the aggressiveness of bladder cancer.
Urologia internationalis 2011;86(1):41-6.
2011: Mun-Ock Kim; Won Sup Lee; Dong-Oh Moon; Yung Hyun Choi; Jin Myung Jung; Gi-Young Kim
Agaricus blazei Extract Induces Apoptosis through ROS-Dependent JNK Activation Involving the Mitochondrial Pathway and Suppression of Constitutive NF-κB in THP-1 Cells.
Evidence-based complementary and alternative medicine : eCAM 2011;2011():838172.
2010: Min Jeong Seo; Min Jeong Kim; Hye Hyeon Lee; Sung Ryeal Kim; Byoung-Won Kang; Jeong-Uck Park; En Ju Rhu; Yung Hyun Choi; Yong Kee Jeong
Initial acidic pH is critical for mycelial cultures and functional exopolysaccharide production of an edible mushroom, Laetiporus sulphureus var. miniatus JM 27.
Journal of microbiology (Seoul, Korea) 2010;48(6):881-4.
2010: In Suk Park; Jeong-Uck Park; Min Jeong Seo; Min Jeong Kim; Hye Hyeon Lee; Sung Ryeal Kim; Byoung-Won Kang; Yung Hyun Choi; Woo Hong Joo; Yong Kee Jeong
Purification and biochemical characterization of a 17 kDa fibrinolytic enzyme from Schizophyllum commune.
Journal of microbiology (Seoul, Korea) 2010;48(6):836-41.
2010: Jin-Woo Jeong; Cheng-Yun Jin; Gi-Young Kim; Jae-Dong Lee; Cheol Park; Gun-Do Kim; Wun-Jae Kim; Won-Kyo Jung; Su Kil Seo; Il-Whan Choi; Yung Hyun Choi
Anti-inflammatory effects of cordycepin via suppression of inflammatory mediators in BV2 microglial cells.
International immunopharmacology 2010;10(12):1580-6.
2010: Eun Young Oh; Ji Yeon Jang; Yung Hyun Choi; Young Whan Choi; Byung Tae Choi
Inhibitory effects of 1-O-methyl-fructofuranose from Schisandra chinensis fruit on melanogenesis in B16F0 melanoma cells.
Journal of ethnopharmacology 2010;132(1):219-24.
2010: Cheol Park; Cheng-Yun Jin; Gi-Young Kim; JaeHun Cheong; Jee H Jung; Young Hyun Yoo; Yung Hyun Choi
A methyl jasmonate derivative, J-7, induces apoptosis in human hepatocarcinoma Hep3B cells in vitro.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(7):1920-6.
2010: Dong-Oh Moon; Yung Hyun Choi; Sung-Kwon Moon; Wun-Jae Kim; Gi-Young Kim
Butein suppresses the expression of nuclear factor-kappa B-mediated matrix metalloproteinase-9 and vascular endothelial growth factor in prostate cancer cells.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(7):1927-34.
2010: Dong-Oh Moon; Sang-Hyuck Kang; Ki-Cheon Kim; Mun-Ock Kim; Yung Hyun Choi; Gi-Young Kim
Sulforaphane decreases viability and telomerase activity in hepatocellular carcinoma Hep3B cells through the reactive oxygen species-dependent pathway.
Cancer letters 2010;295(2):260-6.
2010: Won Sun Park; Won-Kyo Jung; Da-Young Lee; Chisook Moon; Sung Su Yea; Sae-Gwang Park; Su-Kil Seo; Cheol Park; Yung Hyun Choi; Gi-Young Kim; Jung Sik Choi; Il-Whan Choi
Cilostazol protects mice against endotoxin shock and attenuates LPS-induced cytokine expression in RAW 264.7 macrophages via MAPK inhibition and NF-kappaB inactivation: not involved in cAMP mechanisms.
International immunopharmacology 2010;10(9):1077-85.
2010: Dong Yeok Shin; Gi-Young Kim; Jung-In Kim; Moo Kyoung Yoon; Taeg Kyu Kwon; Su-Jae Lee; Young-Whan Choi; Ho Sung Kang; Young Hyun Yoo; Yung Hyun Choi
Anti-invasive activity of diallyl disulfide through tightening of tight junctions and inhibition of matrix metalloproteinase activities in LNCaP prostate cancer cells.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(6):1569-76.
2010: Ji Hoon Jang; Tae Jin Lee; Eun Sun Yang; Do Sik Min; Young Ho Kim; Sang Hyun Kim; Yung Hyun Choi; Jong-Wook Park; Kyeong Sook Choi; Taeg Kyu Kwon
Compound C sensitizes Caki renal cancer cells to TRAIL-induced apoptosis through reactive oxygen species-mediated down-regulation of c-FLIPL and Mcl-1.
Experimental cell research 2010;316(13):2194-203.
2010: Dong-Oh Moon; Mun-Ock Kim; Taek-Jeong Nam; Se-Kwon Kim; Yung Hyun Choi; Gi-Young Kim
Pectenotoxin-2 induces G2/M phase cell cycle arrest in human breast cancer cells via ATM and Chk1/2-mediated phosphorylation of cdc25C.
Oncology reports 2010;24(1):271-6.
2010: Jun-Hyuk Lee; Ji-Yeon Jang; Cheol Park; Byung-Woo Kim; Yung Hyun Choi; Byung-Tae Choi
Curcumin suppresses alpha-melanocyte stimulating hormone-stimulated melanogenesis in B16F10 cells.
International journal of molecular medicine 2010;26(1):101-6.
2010: Hye Young Kim; Hyun Kook Cho; Yung Hyun Choi; Kyu-Sub Lee; JaeHun Cheong
Bile acids increase hepatitis B virus gene expression and inhibit interferon-alpha activity.
The FEBS journal 2010;277(13):2791-802.
2010: Hee Jung Um; Jung Hwa Oh; Yoon-Nyun Kim; Yung Hyun Choi; Sang Hyun Kim; Jong-Wook Park; Taeg Kyu Kwon
The coffee diterpene kahweol sensitizes TRAIL-induced apoptosis in renal carcinoma Caki cells through down-regulation of Bcl-2 and c-FLIP.
Chemico-biological interactions 2010;186(1):36-42.
2010: Dong-Oh Moon; Mun-Ock Kim; Yung Hyun Choi; Gi-Young Kim
Butein sensitizes human hepatoma cells to TRAIL-induced apoptosis via extracellular signal-regulated kinase/Sp1-dependent DR5 upregulation and NF-kappaB inactivation.
Molecular cancer therapeutics 2010;9(6):1583-95.
2010: Dong-Oh Moon; Chang-Hee Kang; Mun-Ock Kim; You-Jin Jeon; Jae-Dong Lee; Yung Hyun Choi; Gi-Young Kim
Beta-lapachone (LAPA) decreases cell viability and telomerase activity in leukemia cells: suppression of telomerase activity by LAPA.
Journal of medicinal food 2010;13(3):481-8.
2010: Jeong Hwan Kim; Soo-Wan Nam; Byung Woo Kim; Wun-Jae Kim; Yung Hyun Choi
Astaxanthin improves the proliferative capacity as well as the osteogenic and adipogenic differentiation potential in neural stem cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2010;48(6):1741-5.
2010: Dong-Oh Moon; Mun-Ock Kim; Sang-Hyuck Kang; Yung Hyun Choi; Sung Yong Park; Gi-Young Kim
HA14-1 sensitizes TNF-alpha-induced apoptosis via inhibition of the NF-kappaB signaling pathway: involvement of reactive oxygen species and JNK.
Cancer letters 2010;292(1):111-8.
2010: Dong-Oh Moon; Mun-Ok Kim; Yung Hyun Choi; Yung-Min Park; Gi-Young Kim
Curcumin attenuates inflammatory response in IL-1beta-induced human synovial fibroblasts and collagen-induced arthritis in mouse model.
International immunopharmacology 2010;10(5):605-10.
2010: Mun-Ock Kim; Dong-Oh Moon; Chang-Hee Kang; Taeg Kyu Kwon; Yung Hyun Choi; Gi-Young Kim
beta-Ionone enhances TRAIL-induced apoptosis in hepatocellular carcinoma cells through Sp1-dependent upregulation of DR5 and downregulation of NF-kappaB activity.
Molecular cancer therapeutics 2010;9(4):833-43.
2010: Yong June Kim; Yun-Sok Ha; Seon-Kyu Kim; Hyung Yoon Yoon; Min Su Lym; Min-Ju Kim; Sung-Kwon Moon; Yung Hyun Choi; Wun-Jae Kim
Gene signatures for the prediction of response to Bacillus Calmette-Guerin immunotherapy in primary pT1 bladder cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(7):2131-7.
2010: Hyun Ju Kwon; Yun Kyung Hong; Cheol Park; Yung Hyun Choi; Hee Jung Yun; Eun Woo Lee; Byung Woo Kim
Widdrol induces cell cycle arrest, associated with MCM down-regulation, in human colon adenocarcinoma cells.
Cancer letters 2010;290(1):96-103.
2010: Kyung-Jun Jang; Min-Ho Han; Byung-Hoon Lee; Byung-Woo Kim; Cheol-Hong Kim; Hyun-Min Yoon; Yung Hyun Choi
Induction of apoptosis by ethanol extracts of Ganoderma lucidum in human gastric carcinoma cells.
Journal of acupuncture and meridian studies 2010;3(1):24-31.
2010: Won-Kyo Jung; Da-Young Lee; Cheol Park; Yung Hyun Choi; Inhak Choi; Sae-Gwang Park; Su-Kil Seo; Soo-Woong Lee; Sung Su Yea; Soon-Cheol Ahn; Chang-Min Lee; Won Sun Park; Jae-Hong Ko; Il-Whan Choi
Cilostazol is anti-inflammatory in BV2 microglial cells by inactivating nuclear factor-kappaB and inhibiting mitogen-activated protein kinases.
British journal of pharmacology 2010;159(6):1274-85.
2010: Jeong Won Yun; Won Sup Lee; Min Jeong Kim; Jing Nan Lu; Myung Hee Kang; Hoon Gu Kim; Dong Chul Kim; Eun Ju Choi; Jin Young Choi; Hae Gyeong Kim; Yun-Kyoung Lee; Chung Ho Ryu; Gonsup Kim; Yung Hyun Choi; Ock Jin Park; Sung Chul Shin
Characterization of a profile of the anthocyanins isolated from Vitis coignetiae Pulliat and their anti-invasive activity on HT-29 human colon cancer cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2010;48(3):903-9.
2010: Jong-Hwan Kim; Young-Whan Choi; Cheol Park; Cheng-Yun Jin; You Jin Lee; Da Jung Park; Sun Guen Kim; Gi-Young Kim; Il-Whan Choi; Won-Deuk Hwang; Yong Kee Jeong; Se-Kwon Kim; Yung Hyun Choi
Apoptosis induction of human leukemia U937 cells by gomisin N, a dibenzocyclooctadiene lignan, isolated from Schizandra chinensis Baill.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2010;48(3):807-13.
2010: Cheol Park; Cheng-Yun Jin; Hyun Ju Kwon; Hye Jin Hwang; Gi-Young Kim; Il-Whan Choi; Taeg Kyu Kwon; Byung-Woo Kim; Wun-Jae Kim; Yung Hyun Choi
Induction of apoptosis by esculetin in human leukemia U937 cells: roles of Bcl-2 and extracellular-regulated kinase signaling.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(2):486-94.
2010: Dong-Oh Moon; Mun-Ock Kim; Yung Hyun Choi; Jin Won Hyun; Weon Young Chang; Gi-Young Kim
Butein induces G(2)/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation.
Cancer letters 2010;288(2):204-13.
2010: Dong-Oh Moon; Mun-Ock Kim; Jae-Dong Lee; Yung Hyun Choi; Gi-Young Kim
Rosmarinic acid sensitizes cell death through suppression of TNF-alpha-induced NF-kappaB activation and ROS generation in human leukemia U937 cells.
Cancer letters 2010;288(2):183-91.
2010: Sung Ok Kim; Yung Hyun Choi
The ethyl alcohol extract of Hizikia fusiforme inhibits matrix metalloproteinase activity and regulates tight junction related protein expression in Hep3B human hepatocarcinoma cells.
Journal of medicinal food 2010;13(1):31-8.
2010: Ji-Yeon Jang; Jun-Hyuk Lee; Hwa Kyoung Shin; Yung Hyun Choi; Jae-Dong Lee; Byung Tae Choi
Partially purified Asiasari radix inhibits melanogenesis through extracellular signal-regulated kinase signaling in B16F10 cells.
International journal of molecular medicine 2010;25(2):287-92.
2010: Jeong-Hwan Kim; Soo-Wan Nam; Byung-Woo Kim; Woobong Choi; Jong-Hwan Lee; Wun-Jae Kim; Yung Hyun Choi
Astaxanthin Improves Stem Cell Potency via an Increase in the Proliferation of Neural Progenitor Cells.
International journal of molecular sciences 2010;11(12):5109-19.
2010: Won Tae Kim; Seok Joong Yun; Cheol Park; Isaac Yi Kim; Sung-Kwon Moon; Tae Gyun Kwon; Yung Hyun Choi; Wun-Jae Kim
Identification of C16orf74 as a marker of progression in primary non-muscle invasive bladder cancer.
PloS one 2010;5(12):e15260.
2010: Yun-Sok Ha; Chunri Yan; Min Su Lym; Pildu Jeong; Won Tae Kim; Yong June Kim; Seok-Joong Yun; Sang-Cheol Lee; Sung-Kwon Moon; Yung Hyun Choi; Wun-Jae Kim
GSTT1 as a prognosticator for recurrence and progression in patients with non-muscle-invasive bladder cancer.
Disease markers 2010;29(2):81-7.
2010: Seong-Yun Jeong; Min Ho Han; Cheng-Yun Jin; Gi-Young Kim; Byung Tae Choi; Taek-Jeong Nam; Se-Kwon Kim; Yung Hyun Choi
Apoptosis induction of human leukemia cells by Streptomyces sp. SY-103 metabolites through activation of caspase-3 and inactivation of Akt.
International journal of molecular medicine 2010;25(1):31-40.
2010: Chang-Hwan Yoon; Min-Jung Kim; Myung-Jin Park; In-Chul Park; Sang-Gu Hwang; Sungkwan An; Yung Hyun Choi; Gyesoon Yoon; Su-Jae Lee
Claudin-1 acts through c-Abl-protein kinase Cdelta (PKCdelta) signaling and has a causal role in the acquisition of invasive capacity in human liver cells.
The Journal of biological chemistry 2010;285(1):226-33.
2009: Dong-Oh Moon; Mun-Ock Kim; Jae-Dong Lee; Yung Hyun Choi; Gi-Young Kim
Butein suppresses c-Myc-dependent transcription and Akt-dependent phosphorylation of hTERT in human leukemia cells.
Cancer letters 2009;286(2):172-9.
2009: Dong Yeok Shin; Won Sup Lee; Jing Nan Lu; Myung Hee Kang; Chung Ho Ryu; Gi Young Kim; Ho Sung Kang; Sung Chul Shin; Yung Hyun Choi
Induction of apoptosis in human colon cancer HCT-116 cells by anthocyanins through suppression of Akt and activation of p38-MAPK.
International journal of oncology 2009;35(6):1499-504.
2009: Jeong Hae Choi; Hyun Kook Cho; Yung Hyun Choi; JaeHun Cheong
Activating transcription factor 2 increases transactivation and protein stability of hypoxia-inducible factor 1alpha in hepatocytes.
The Biochemical journal 2009;424(2):285-96.
2009: Yung Hyun Choi; G H Yan
Anti-allergic effects of scoparone on mast cell-mediated allergy model.
Phytomedicine : international journal of phytotherapy and phytopharmacology 2009;16(12):1089-94.
2009: Woo Young Choi; Cheng-Yun Jin; Min Ho Han; Gi-Young Kim; Nam Deuk Kim; Won Ho Lee; Se-Kwon Kim; Yung Hyun Choi
Sanguinarine sensitizes human gastric adenocarcinoma AGS cells to TRAIL-mediated apoptosis via down-regulation of AKT and activation of caspase-3.
Anticancer research 2009;29(11):4457-65.
2009: Jeong-Hwan Kim; Woobong Choi; Jong-Hwan Lee; Sung-Jong Jeon; Yung Hyun Choi; Byung-Woo Kim; Hyo-Ihl Chang; Soo-Wan Nam
Astaxanthin inhibits H2O2-mediated apoptotic cell death in mouse neural progenitor cells via modulation of P38 and MEK signaling pathways.
Journal of microbiology and biotechnology 2009;19(11):1355-63.
2009: Jung Hwa Oh; Jung Tae Lee; Eun Sun Yang; Jong-Soo Chang; Dong Sun Lee; Sang Hyun Kim; Yung Hyun Choi; Jong-Wook Park; Taeg Kyu Kwon
The coffee diterpene kahweol induces apoptosis in human leukemia U937 cells through down-regulation of Akt phosphorylation and activation of JNK.
Apoptosis : an international journal on programmed cell death 2009;14(11):1378-86.
2009: Sung Ok Kim; Byung Tae Choi; Il-Whan Choi; Jaehun Cheong; Gi-Young Kim; Taeg Kyu Kwon; Nam Deuk Kim; Yung Hyun Choi
Anti-invasive activity of histone deacetylase inhibitors via the induction of Egr-1 and the modulation of tight junction-related proteins in human hepatocarcinoma cells.
BMB reports 2009;42(10):655-60.
2009: Dong-Oh Moon; Mun-Ock Kim; Moon-Soo Heo; Jae-Dong Lee; Yung Hyun Choi; Gi-Young Kim
Gefitinib induces apoptosis and decreases telomerase activity in MDA-MB-231 human breast cancer cells.
Archives of pharmacal research 2009;32(10):1351-60.
2009: Dong Yeok Shin; Won Sup Lee; Seok Hyun Kim; Min Jeong Kim; Jeong Won Yun; Jing Nan Lu; Sung Joong Lee; Irina Tsoy; Hye Jung Kim; Chung Ho Ryu; Gi Young Kim; Ho Sung Kang; Sung Chul Shin; Yung Hyun Choi
Anti-invasive activity of anthocyanins isolated from Vitis coignetiae in human hepatocarcinoma cells.
Journal of medicinal food 2009;12(5):967-72.
2009: Cheol Park; Young-Whan Choi; Sook Kyung Hyun; Hyun Ju Kwon; Hye Jin Hwang; Gi-Young Kim; Byung Tae Choi; Byung-Woo Kim; Il-Whan Choi; Sung-Kwon Moon; Wun-Jae Kim; Yung Hyun Choi
Induction of G1 arrest and apoptosis by schisandrin C isolated from Schizandra chinensis Baill in human leukemia U937 cells.
International journal of molecular medicine 2009;24(4):495-502.
2009: Dong-Oh Moon; Mun Ock Kim; Chang Hee Kang; Jae Dong Lee; Yung Hyun Choi; Gi Young Kim
JNK inhibitor SP600125 promotes the formation of polymerized tubulin, leading to G2/M phase arrest, endoreduplication, and delayed apoptosis.
Experimental & molecular medicine 2009;41(9):665-77.
2009: Hye Ri Yun; Hwa-Seung Yoo; Dong Yeok Shin; Su Hyun Hong; Jong-Hwan Kim; Chong Kwan Cho; Yung Hyun Choi
Apoptosis induction of human lung carcinoma cells by Chan Su (Venenum Bufonis) through activation of caspases.
Journal of acupuncture and meridian studies 2009;2(3):210-7.
2009: Cheng-Yun Jin; Cheol Park; Sung-Kwon Moon; Gi-Young Kim; Taeg Kyu Kwon; Su-Jae Lee; Wun-Jae Kim; Yung Hyun Choi
Genistein sensitizes human hepatocellular carcinoma cells to TRAIL-mediated apoptosis by enhancing Bid cleavage.
Anti-cancer drugs 2009;20(8):713-22.
2009: Tae-Yeon Kim; Cheng-Yun Jin; Gi-Young Kim; Il-Whan Choi; Yong Kee Jeong; Taek-Jeong Nam; Se-Kwon Kim; Yung Hyun Choi
Ethyl alcohol extracts of Hizikia fusiforme sensitize AGS human gastric adenocarcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis.
Journal of medicinal food 2009;12(4):782-7.
2009: Dong Yeok Shin; Chung Ho Ryu; Won Sup Lee; Dong Chul Kim; Seok Hyun Kim; Young-Sool Hah; Sung Joong Lee; Sung Chul Shin; Ho Sung Kang; Yung Hyun Choi
Induction of apoptosis and inhibition of invasion in human hepatoma cells by anthocyanins from meoru.
Annals of the New York Academy of Sciences 2009;1171():137-48.
2009: Ji Yeon Jang; Jun Hyuk Lee; Seong-Yun Jeong; Kyung Tae Chung; Yung Hyun Choi; Byung Tae Choi
Partially purified Curcuma longa inhibits alpha-melanocyte-stimulating hormone-stimulated melanogenesis through extracellular signal-regulated kinase or Akt activation-mediated signalling in B16F10 cells.
Experimental dermatology 2009;18(8):689-94.
2009: Cheng-Yun Jin; Cheol Park; Gi-Young Kim; Su-Jae Lee; Wun-Jae Kim; Yung Hyun Choi
Genistein enhances TRAIL-induced apoptosis through inhibition of p38 MAPK signaling in human hepatocellular carcinoma Hep3B cells.
Chemico-biological interactions 2009;180(2):143-50.
2009: Won-Kyo Jung; Ik-Su Park; Sang-Jun Park; Sung Su Yea; Yung Hyun Choi; Sangtaek Oh; Sae-Gwang Park; Il-Whan Choi
The 15-deoxy-Delta12,14-prostaglandin J2 inhibits LPS-stimulated AKT and NF-kappaB activation and suppresses interleukin-6 in osteoblast-like cells MC3T3E-1.
Life sciences 2009;85(1-2):46-53.
2009: Seung Chan Park; Hwa-Seung Yoo; Cheol Park; Chong-Kwan Cho; Gi-Young Kim; Wun-Jae Kim; Yeon-Weol Lee; Yung Hyun Choi
Induction of apoptosis in human lung carcinoma cells by the water extract of Panax notoginseng is associated with the activation of caspase-3 through downregulation of Akt.
International journal of oncology 2009;35(1):121-7.
2009: Sang Eun Park; Hwa-Seung Yoo; Cheng-Yun Jin; Sang Hoon Hong; Yeon-Weol Lee; Byung Woo Kim; Shin Hwa Lee; Wun-Jae Kim; Chong-Kwan Cho; Yung Hyun Choi
Induction of apoptosis and inhibition of telomerase activity in human lung carcinoma cells by the water extract of Cordyceps militaris.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2009;47(7):1667-75.
2009: Won-Kyo Jung; Soo-Jin Heo; You-Jin Jeon; Chang-Min Lee; Yeong-Min Park; Hee-Guk Byun; Yung Hyun Choi; Sae-Gwang Park; Il-Whan Choi
Inhibitory effects and molecular mechanism of dieckol isolated from marine brown alga on COX-2 and iNOS in microglial cells.
Journal of agricultural and food chemistry 2009;57(10):4439-46.
2009: Yung Hyun Choi; Woo Young Choi; Su Hyun Hong; Sung Ok Kim; Gi-Young Kim; Won Ho Lee; Young Hyun Yoo
Anti-invasive activity of sanguinarine through modulation of tight junctions and matrix metalloproteinase activities in MDA-MB-231 human breast carcinoma cells.
Chemico-biological interactions 2009;179(2-3):185-91.
2009: Shin Hwa Lee; Su Min Park; Suk Min Park; Jae Hyeon Park; Dong Yeok Shin; Gi Young Kim; Chung Ho Ryu; Sung Chul Shin; Jin Myung Jung; Ho Sung Kang; Won Sup Lee; Yung Hyun Choi
Induction of apoptosis in human leukemia U937 cells by anthocyanins through down-regulation of Bcl-2 and activation of caspases.
International journal of oncology 2009;34(4):1077-83.
2009: Sang Ho Seo; Dong Yeok Shin; Sang Hoon Hong; Sang Eun Park; Yung Hyun Choi; Sang Hoon Hong
Euphorbiae humifusae induces apoptosis in Hep3B hepatocarcinoma cells via simultaneous activation of the death receptor-mediated and mitochondrial pathways.
Molecular medicine reports 2009;2(2):221-7.
2009: Cheng-Yun Jin; Cheol Park; Jun-Hyuk Lee; Kyung Tae Chung; Taeg Kyu Kwon; Gi-Young Kim; Byung Tae Choi; Yung Hyun Choi
Naringenin-induced apoptosis is attenuated by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human leukemia U937 cells.
Toxicology in vitro : an international journal published in association with BIBRA 2009;23(2):259-65.
2009: Ji Yeon Jang; Jun Hyuk Lee; Byoung-Won Kang; Kyung Tae Chung; Yung Hyun Choi; Byung Tae Choi
Dichloromethane fraction of Cimicifuga heracleifolia decreases the level of melanin synthesis by activating the ERK or AKT signaling pathway in B16F10 cells.
Experimental dermatology 2009;18(3):232-7.
2009: Dong-Oh Moon; Mun-Ock Kim; Sang-Hyuck Kang; Yung Hyun Choi; Gi-Young Kim
Sulforaphane suppresses TNF-alpha-mediated activation of NF-kappaB and induces apoptosis through activation of reactive oxygen species-dependent caspase-3.
Cancer letters 2009;274(1):132-42.
2009: Won-Kyo Jung; Young-Wook Ahn; Sang-Hoon Lee; Yung Hyun Choi; Se-Kwon Kim; Sung Su Yea; Inhak Choi; Sae-Gwang Park; Su-Kil Seo; Soo-Woong Lee; Il-Whan Choi
Ecklonia cava ethanolic extracts inhibit lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in BV2 microglia via the MAP kinase and NF-kappaB pathways.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2009;47(2):410-7.
2009: Dong Yeok Shin; Gi Young Kim; Wei Li; Byung Tae Choi; Nam Deuk Kim; Ho Sung Kang; Yung Hyun Choi
Implication of intracellular ROS formation, caspase-3 activation and Egr-1 induction in platycodon D-induced apoptosis of U937 human leukemia cells.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2009;63(2):86-94.
2009: Sang Eun Park; Cheol Park; Sun Hee Kim; Mohammad Akbar Hossain; Min Young Kim; Hae Young Chung; Woo Sung Son; Gi-Young Kim; Yung Hyun Choi; Nam Deuk Kim
Korean red ginseng extract induces apoptosis and decreases telomerase activity in human leukemia cells.
Journal of ethnopharmacology 2009;121(2):304-12.
2008: Cheng-Yun Jin; Gi-Young Kim; Yung Hyun Choi
Induction of apoptosis by aqueous extract of Cordyceps militaris through activation of caspases and inactivation of Akt in human breast cancer MDA-MB-231 Cells.
Journal of microbiology and biotechnology 2008;18(12):1997-2003.
2008: Jung Hwa Oh; Tae-Jin Lee; Sang Hyun Kim; Yung Hyun Choi; Sang-Han Lee; Jin Man Lee; Young-Ho Kim; Jong-Wook Park; Taeg Kyu Kwon
Induction of apoptosis by withaferin A in human leukemia U937 cells through down-regulation of Akt phosphorylation.
Apoptosis : an international journal on programmed cell death 2008;13(12):1494-504.
2008: Joon Hee Park; Cheng-Yun Jin; Bok Kyu Lee; Gi-Young Kim; Yung Hyun Choi; Yong Kee Jeong
Naringenin induces apoptosis through downregulation of Akt and caspase-3 activation in human leukemia THP-1 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(12):3684-90.
2008: Shin Hwa Lee; Cheol Park; Cheng-Yun Jin; Gi-Young Kim; Sung-Kwon Moon; Jin Won Hyun; Won Ho Lee; Byung Tae Choi; Taeg Kyu Kwon; Young Hyun Yoo; Yung Hyun Choi
Involvement of extracellular signal-related kinase signaling in esculetin induced G1 arrest of human leukemia U937 cells.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2008;62(10):723-9.
2008: Mun-Ock Kim; Dong-Oh Moon; Moon-Soo Heo; Jae-Dong Lee; Jee Hyung Jung; Se-Kwon Kim; Yung Hyun Choi; Gi-Young Kim
Pectenotoxin-2 abolishes constitutively activated NF-kappaB, leading to suppression of NF-kappaB related gene products and potentiation of apoptosis.
Cancer letters 2008;271(1):25-33.
2008: Dong Yeok Shin; Hee Jae Shin; Gi-Young Kim; JaeHun Cheong; Il-Whan Choi; Se-Kwon Kim; Sung-Kwon Moon; Ho Sung Kang; Yung Hyun Choi
Streptochlorin isolated from Streptomyces sp. Induces apoptosis in human hepatocarcinoma cells through a reactive oxygen species-mediated mitochondrial pathway.
Journal of microbiology and biotechnology 2008;18(11):1862-8.
2008: Jun Hee Lim; Jong-Wook Park; Sang Hyun Kim; Yung Hyun Choi; Kyeong Sook Choi; Taeg Kyu Kwon
Rottlerin induces pro-apoptotic endoplasmic reticulum stress through the protein kinase C-delta-independent pathway in human colon cancer cells.
Apoptosis : an international journal on programmed cell death 2008;13(11):1378-85.
2008: Woo Young Choi; Byung Tae Choi; Won Ho Lee; Yung Hyun Choi
Sulforaphane generates reactive oxygen species leading to mitochondrial perturbation for apoptosis in human leukemia U937 cells.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2008;62(9):637-44.
2008: Sang Eun Park; Sun Wha Lee; Mohammad Akbar Hossain; Min Young Kim; Mi-Na Kim; Eun Young Ahn; Young Chul Park; Hongsuk Suh; Gi-Young Kim; Yung Hyun Choi; Nam Deuk Kim
A chenodeoxycholic derivative, HS-1200, induces apoptosis and cell cycle modulation via Egr-1 gene expression control on human hepatoma cells.
Cancer letters 2008;270(1):77-86.
2008: Dong-Oh Moon; Mun-Ock Kim; Hee-Jeong Lee; Yung Hyun Choi; Yeong-Min Park; Moon-Soo Heo; Gi-Young Kim
Curcumin attenuates ovalbumin-induced airway inflammation by regulating nitric oxide.
Biochemical and biophysical research communications 2008;375(2):275-9.
2008: Dong-Oh Moon; Mun-Ock Kim; Yung Hyun Choi; Hee Gu Lee; Nam Deuk Kim; Gi-Young Kim
Gossypol suppresses telomerase activity in human leukemia cells via regulating hTERT.
FEBS letters 2008;582(23-24):3367-73.
2008: Mun-Ock Kim; Dong-Oh Moon; Sang-Hyuck Kang; Moon-Soo Heo; Yung Hyun Choi; Jee Hyung Jung; Jae-Dong Lee; Gi-Young Kim
Pectenotoxin-2 represses telomerase activity in human leukemia cells through suppression of hTERT gene expression and Akt-dependent hTERT phosphorylation.
FEBS letters 2008;582(23-24):3263-9.
2008: Chang-Min Lee; Jeong-Hyun Chang; Dong-Oh Moon; Yung Hyun Choi; Il-Whan Choi; Yeong-Min Park; Gi-Young Kim
Lycopene suppresses ovalbumin-induced airway inflammation in a murine model of asthma.
Biochemical and biophysical research communications 2008;374(2):248-52.
2008: Cheol Park; Hee Jae Shin; Gi-Young Kim; Taeg Kyu Kwon; Taek-Jeong Nam; Se-Kwon Kim; JaeHun Cheong; Il-Whan Choi; Yung Hyun Choi
Induction of apoptosis by streptochlorin isolated from Streptomyces sp. in human leukemic U937 cells.
Toxicology in vitro : an international journal published in association with BIBRA 2008;22(6):1573-81.
2008: Dong-Oh Moon; Mun-Ock Kim; Sang-Hyuck Kang; Kyeong-Jun Lee; Moon-Soo Heo; Kwang-Sik Choi; Yung Hyun Choi; Gi-Young Kim
Induction of G2/M arrest, endoreduplication, and apoptosis by actin depolymerization agent pextenotoxin-2 in human leukemia cells, involving activation of ERK and JNK.
Biochemical pharmacology 2008;76(3):312-21.
2008: Hyun Kook Cho; Bo-Hye Nam; Hee Jeong Kong; Hyon Sob Han; Young Baek Hur; Tae Jin Choi; Yung Hyun Choi; Woo Jin Kim; JaeHun Cheong
Identification of softness syndrome-associated candidate genes and DNA sequence variation in the sea squirt, Halocynthia roretzi.
Marine biotechnology (New York, N.Y.) 2008;10(4):447-56.
2008: Dong-Oh Moon; Mun-Ock Kim; Yung Hyun Choi; Nam Deuk Kim; Jeong-Hyun Chang; Gi-Young Kim
Bcl-2 overexpression attenuates SP600125-induced apoptosis in human leukemia U937 cells.
Cancer letters 2008;264(2):316-25.
2008: Dong-Oh Moon; Mun-Ock Kim; Yung Hyun Choi; Gi-Young Kim
beta-Sitosterol induces G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways.
Cancer letters 2008;264(2):181-91.
2008: Mun-Ock Kim; Dong-Oh Moon; Yung Hyun Choi; Jae-Dong Lee; Nam Deuk Kim; Gi-Young Kim
Platycodin D induces mitotic arrest in vitro, leading to endoreduplication, inhibition of proliferation and apoptosis in leukemia cells.
International journal of cancer. Journal international du cancer 2008;122(12):2674-81.
2008: Sang Man Lee; Jae Im Kwon; Yung Hyun Choi; Hyun Sup Eom; Gyoo Yong Chi
Induction of G2/M arrest and apoptosis by water extract of Strychni Semen in human gastric carcinoma AGS cells.
Phytotherapy research : PTR 2008;22(6):752-8.
2008: Se-Kwon Kim; Da-Young Lee; Won-Kyo Jung; Ji-Hye Kim; Inhak Choi; Sae-Gwang Park; Su-Kil Seo; Soo-Woong Lee; Chang Min Lee; Sung Su Yea; Yung Hyun Choi; Il-Whan Choi
Effects of Ecklonia cava ethanolic extracts on airway hyperresponsiveness and inflammation in a murine asthma model: role of suppressor of cytokine signaling.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2008;62(5):289-96.
2008: Won Il Park; Min Jung Park; Jin Kwang An; Yung Hyun Choi; Hye Young Kim; JaeHun Cheong; Ung Suk Yang
Bile acid regulates c-Jun expression through the orphan nuclear receptor SHP induction in gastric cells.
Biochemical and biophysical research communications 2008;369(2):437-43.
2008: Yeong Hoon Kim; Cheol Park; Jeong Ok Lee; Gi Young Kim; Won Ho Lee; Yung Hyun Choi; Chung Ho Ryu
Induction of apoptosis by piceatannol in human leukemic U937 cells through down-regulation of Bcl-2 and activation of caspases.
Oncology reports 2008;19(4):961-7.
2008: Ji-Won Ryu; Jun-Hyuk Lee; Yung Hyun Choi; Yong-Tae Lee; Byung Tae Choi
Effects of protein phosphatase inhibitors on the phosphorylation of spinal cord N-methyl-D-aspartate receptors following electroacupuncture stimulation in rats.
Brain research bulletin 2008;75(5):687-91.
2008: Won-Kyo Jung; Da-Young Lee; Yung Hyun Choi; Sung Su Yea; Inhak Choi; Sae-Gwang Park; Su K Seo; Soo-Woong Lee; Chang-Min Lee; Se-Kwon Kim; You-Jin Jeon; Il-Whan Choi
Caffeic acid phenethyl ester attenuates allergic airway inflammation and hyperresponsiveness in murine model of ovalbumin-induced asthma.
Life sciences 2008;82(13-14):797-805.
2008: Yeoun Hee Kim; Eun Mi Jung; Tae-Jin Lee; Sang Hyun Kim; Yung Hyun Choi; Jeen-Woo Park; Jong-Wook Park; Kyeong Sook Choi; Taeg Kyu Kwon
Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP.
Free radical biology & medicine 2008;44(6):1055-68.
2008: Mun-Ock Kim; Dong-Oh Moon; Yung Hyun Choi; Dong Yeok Shin; Ho Sung Kang; Byung Tae Choi; Jae-Dong Lee; Wei Li; Gi-Young Kim
Platycodin D induces apoptosis and decreases telomerase activity in human leukemia cells.
Cancer letters 2008;261(1):98-107.
2008: Jae Im Kwon; Gi-Young Kim; Kun-Young Park; Chung Ho Ryu; Yung Hyun Choi
Induction of apoptosis by linoleic acid is associated with the modulation of Bcl-2 family and Fas/FasL system and activation of caspases in AGS human gastric adenocarcinoma cells.
Journal of medicinal food 2008;11(1):1-8.
2008: Cheol Park; Cheng-Yun Jin; Gi-Young Kim; Il-Whan Choi; Taeg Kyu Kwon; Byung Tae Choi; Su-Jae Lee; Won Ho Lee; Yung Hyun Choi
Induction of apoptosis by esculetin in human leukemia U937 cells through activation of JNK and ERK.
Toxicology and applied pharmacology 2008;227(2):219-28.
2008: Dong Yeok Shin; Gi Young Kim; Nam Deuk Kim; Jee H Jung; Se-Kwon Kim; Ho Sung Kang; Yung Hyun Choi
Induction of apoptosis by pectenotoxin-2 is mediated with the induction of DR4/DR5, Egr-1 and NAG-1, activation of caspases and modulation of the Bcl-2 family in p53-deficient Hep3B hepatocellular carcinoma cells.
Oncology reports 2008;19(2):517-26.
2008: Tae-Jin Lee; Jung-Tae Lee; Sang Hyun Kim; Yung Hyun Choi; Kyoung Seob Song; Jong-Wook Park; Taeg Kyu Kwon
Overexpression of Par-4 enhances thapsigargin-induced apoptosis via down-regulation of XIAP and inactivation of Akt in human renal cancer cells.
Journal of cellular biochemistry 2008;103(2):358-68.
2008: Hyun Yang; Duk Hwa Chung; Yung Bu Kim; Yung Hyun Choi; Yuseok Moon
Ribotoxic mycotoxin deoxynivalenol induces G2/M cell cycle arrest via p21Cip/WAF1 mRNA stabilization in human epithelial cells.
Toxicology 2008;243(1-2):145-54.
2008: Woo Young Choi; Gi-Young Kim; Won Ho Lee; Yung Hyun Choi
Sanguinarine, a benzophenanthridine alkaloid, induces apoptosis in MDA-MB-231 human breast carcinoma cells through a reactive oxygen species-mediated mitochondrial pathway.
Chemotherapy 2008;54(4):279-87.
2008: Won-Kyo Jung; Inhak Choi; Da-Young Lee; Sung Su Yea; Yung Hyun Choi; Moon-Moo Kim; Sae-Gwang Park; Su-Kil Seo; Soo-Woong Lee; Chang-Min Lee; Yeong-Min Park; Il-Whan Choi
Caffeic acid phenethyl ester protects mice from lethal endotoxin shock and inhibits lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW 264.7 macrophages via the p38/ERK and NF-kappaB pathways.
The international journal of biochemistry & cell biology 2008;40(11):2572-82.
2008: Min Ho Han; Young Hyun Yoo; Yung Hyun Choi
Sanguinarine-induced apoptosis in human leukemia U937 cells via Bcl-2 downregulation and caspase-3 activation.
Chemotherapy 2008;54(3):157-65.
2008: Eun Mi Jung; Tae-Jin Lee; Jong-Wook Park; Yoe-Sik Bae; Sang Hyun Kim; Yung Hyun Choi; Taeg Kyu Kwon
The novel phospholipase C activator, m-3M3FBS, induces apoptosis in tumor cells through caspase activation, down-regulation of XIAP and intracellular calcium signaling.
Apoptosis : an international journal on programmed cell death 2008;13(1):133-45.
2008: Dong-Oh Moon; Sung-Yong Park; Yung Hyun Choi; Nam Deuk Kim; Chan Lee; Gi-Young Kim
Melittin induces Bcl-2 and caspase-3-dependent apoptosis through downregulation of Akt phosphorylation in human leukemic U937 cells.
Toxicon : official journal of the International Society on Toxinology 2008;51(1):112-20.
2008: Sae-Gwang Park; Da-Young Lee; Su K Seo; Soo-Woong Lee; Se-Kwon Kim; Won-Kyo Jung; Mi-Seon Kang; Yung Hyun Choi; Sung Su Yea; Inhak Choi; Il-Whan Choi
Evaluation of anti-allergic properties of caffeic acid phenethyl ester in a murine model of systemic anaphylaxis.
Toxicology and applied pharmacology 2008;226(1):22-9.
2007: Cheng-Yun Jin; Cheol Park; JaeHun Cheong; Byung Tae Choi; Tae Ho Lee; Jae-Dong Lee; Won Ho Lee; Gi-Young Kim; Chung Ho Ryu; Yung Hyun Choi
Genistein sensitizes TRAIL-resistant human gastric adenocarcinoma AGS cells through activation of caspase-3.
Cancer letters 2007;257(1):56-64.
2007: Jeong Ok Lee; Mi Hwa Park; Yung Hyun Choi; Yeong L Ha; Chung Ho Ryu
New fermentation technique for complete digestion of soybean protein.
Journal of microbiology and biotechnology 2007;17(11):1904-7.
2007: Jong-Wook Park; Kyung Jin Woo; Jung-Tae Lee; Jun Hee Lim; Tae-Jin Lee; Sang Hyun Kim; Yung Hyun Choi; Taeg Kyu Kwon
Resveratrol induces pro-apoptotic endoplasmic reticulum stress in human colon cancer cells.
Oncology reports 2007;18(5):1269-73.
2007: Kyeong Jin Kim; Hyeong Hoe Kim; Joon Hong Kim; Yung Hyun Choi; Young Hee Kim; Jae Hun Cheong
Chemokine stromal cell-derived factor-1 induction by C/EBPbeta activation is associated with all-trans-retinoic acid-induced leukemic cell differentiation.
Journal of leukocyte biology 2007;82(5):1332-9.
2007: Cheng-Yun Jin; Jae-Dong Lee; Cheol Park; Yung Hyun Choi; Gi-Young Kim
Curcumin attenuates the release of pro-inflammatory cytokines in lipopolysaccharide-stimulated BV2 microglia.
Acta pharmacologica Sinica 2007;28(10):1645-51.
2007: Sung Ok Kim; Jae Im Kwon; Yong Kee Jeong; Gi Young Kim; Nam Deuk Kim; Yung Hyun Choi
Induction of Egr-1 is associated with anti-metastatic and anti-invasive ability of beta-lapachone in human hepatocarcinoma cells.
Bioscience, biotechnology, and biochemistry 2007;71(9):2169-76.
2007: Cheol Park; Dong-Oh Moon; Il-Whan Choi; Byung Tae Choi; Taek-Jeong Nam; Chung-Ho Rhu; Taeg Kyu Kwon; Won Ho Lee; Gi-Young Kim; Yung Hyun Choi
Curcumin induces apoptosis and inhibits prostaglandin E(2) production in synovial fibroblasts of patients with rheumatoid arthritis.
International journal of molecular medicine 2007;20(3):365-72.
2007: Min Ho Han; Sung Ok Kim; Gi Young Kim; Taeg Kyu Kwon; Byung Tae Choi; Won Ho Lee; Yung Hyun Choi
Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt.
Anti-cancer drugs 2007;18(8):913-21.
2007: Cheng-Yun Jin; Dong-Oh Moon; Yung Hyun Choi; Jae-Dong Lee; Gi-Young Kim
Bcl-2 and caspase-3 are major regulators in Agaricus blazei-induced human leukemic U937 cell apoptosis through dephoshorylation of Akt.
Biological & pharmaceutical bulletin 2007;30(8):1432-7.
2007: Dong-Oh Moon; Moon-ok Kim; Jae-dong Lee; Yung Hyun Choi; Min-ki Lee; Gi-Young Kim
Molecular mechanisms of ZD1839 (Iressa)-induced apoptosis in human leukemic U937 cells.
Acta pharmacologica Sinica 2007;28(8):1205-14.
2007: Dong-Oh Moon; Sung-Yong Park; Kyeong-Jun Lee; Moon-Soo Heo; Ki-Cheon Kim; Mun-Ock Kim; Jae-Dong Lee; Yung Hyun Choi; Gi-Young Kim
Bee venom and melittin reduce proinflammatory mediators in lipopolysaccharide-stimulated BV2 microglia.
International immunopharmacology 2007;7(8):1092-101.
2007: Dong-Oh Moon; Kyeong-Jun Lee; Yung Hyun Choi; Gi-Young Kim
Beta-sitosterol-induced-apoptosis is mediated by the activation of ERK and the downregulation of Akt in MCA-102 murine fibrosarcoma cells.
International immunopharmacology 2007;7(8):1044-53.
2007: Cheol Park; Dong-Oh Moon; Chung-Ho Rhu; Byung Tae Choi; Won Ho Lee; Gi-Young Kim; Yung Hyun Choi
Beta-sitosterol induces anti-proliferation and apoptosis in human leukemic U937 cells through activation of caspase-3 and induction of Bax/Bcl-2 ratio.
Biological & pharmaceutical bulletin 2007;30(7):1317-23.
2007: Soung Young Park; Gi-Young Kim; Song-Ja Bae; Young Hyun Yoo; Yung Hyun Choi
Induction of apoptosis by isothiocyanate sulforaphane in human cervical carcinoma HeLa and hepatocarcinoma HepG2 cells through activation of caspase-3.
Oncology reports 2007;18(1):181-7.
2007: Young-Ae Kim; Gi-Young Kim; Kun-Young Park; Yung Hyun Choi
Resveratrol inhibits nitric oxide and prostaglandin E2 production by lipopolysaccharide-activated C6 microglia.
Journal of medicinal food 2007;10(2):218-24.
2007: Jun Sik Lee; In Duk Jung; Young-Il Jeong; Chang-Min Lee; Yong Kyoo Shin; Sang-Yull Lee; Dong-Soo Suh; Man-Soo Yoon; Kyu-Sub Lee; Yung Hyun Choi; Hae Young Chung; Yeong-Min Park
D-pinitol inhibits Th1 polarization via the suppression of dendritic cells.
International immunopharmacology 2007;7(6):791-804.
2007: Cheng-Yun Jin; Dong-Oh Moon; Jae-Dong Lee; Moon-Soo Heo; Yung Hyun Choi; Chang-Min Lee; Yeong-Min Park; Gi-Young Kim
Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis through downregulation of ERK and Akt in lung adenocarcinoma A549 cells.
Carcinogenesis 2007;28(5):1058-66.
2007: Dong-Oh Moon; Yung Hyun Choi; Nam-Duk Kim; Yeong-Min Park; Gi-Young Kim
Anti-inflammatory effects of beta-lapachone in lipopolysaccharide-stimulated BV2 microglia.
International immunopharmacology 2007;7(4):506-14.
2007: Min Jung Park; Min Young Lee; Jung Hae Choi; Hyun Kook Cho; Yung Hyun Choi; Ung Suk Yang; JaeHun Cheong
Phosphorylation of the large subunit of replication factor C is associated with adipocyte differentiation.
The FEBS journal 2007;274(5):1235-45.
2007: Dong-Oh Moon; Ki-Cheon Kim; Cheng-Yun Jin; Min-Ho Han; Cheol Park; Kyeong-Jun Lee; Yeong-Min Park; Yung Hyun Choi; Gi-Young Kim
Inhibitory effects of eicosapentaenoic acid on lipopolysaccharide-induced activation in BV2 microglia.
International immunopharmacology 2007;7(2):222-9.
2007: Jun Sik Lee; Sang Gap Kim; Hyung Keun Kim; TAE HYUNG LEE; Young-Il Jeong; Chang-Min Lee; Man-Soo Yoon; Yong Jin Na; Dong-Soo Suh; Nam Cheol Park; In-Hak Choi; Gi-Young Kim; Yung Hyun Choi; Hae Young Chung; Yeong-Min Park
Silibinin polarizes Th1/Th2 immune responses through the inhibition of immunostimulatory function of dendritic cells.
Journal of cellular physiology 2007;210(2):385-97.
2007: Hyun Joo Woo; Su-Jae Lee; Byung Tae Choi; Yeong-Min Park; Yung Hyun Choi
Induction of apoptosis and inhibition of telomerase activity by trichostatin A, a histone deacetylase inhibitor, in human leukemic U937 cells.
Experimental and molecular pathology 2007;82(1):77-84.
2007: Cheol Park; Gi-Young Kim; Won Il Kim; Sang Hoon Hong; Dong Il Park; Nam Deuk Kim; Song-Ja Bae; Jee H Jung; Yung Hyun Choi
Induction of apoptosis by (Z)-stellettic acid C, an acetylenic acid from the sponge Stelletta sp., is associated with inhibition of telomerase activity in human leukemic U937 cells.
Chemotherapy 2007;53(3):160-8.
2007: Gi-Young Kim; Ho-Jin Chae; Ki-Hyung Kim; Man-Soo Yoon; Kyu-Sub Lee; Chang-Min Lee; Dong-Oh Moon; Jun-Sik Lee; Young-Il Jeong; Yung Hyun Choi; Yeong-Min Park
Dendritic cell-tumor fusion vaccine prevents tumor growth in vivo.
Bioscience, biotechnology, and biochemistry 2007;71(1):215-21.
2007: Dong-Oh Moon; Cheol Park; Moon-Soo Heo; Yeong-Min Park; Yung Hyun Choi; Gi-Young Kim
PD98059 triggers G1 arrest and apoptosis in human leukemic U937 cells through downregulation of Akt signal pathway.
International immunopharmacology 2007;7(1):36-45.
2007: Cheol Park; Jee H Jung; Nam Deuk Kim; Yung Hyun Choi
Inhibition of cyclooxygenase-2 and telomerase activities in human leukemia cells by dideoxypetrosynol A, a polyacetylene from the marine sponge Petrosia sp.
International journal of oncology 2007;30(1):291-8.
2007: Song Ja Bae; Yung Hyun Choi
Methanol extract of the seaweed Gloiopeltis furcata induces G2/M arrest and inhibits cyclooxygenase-2 activity in human hepatocarcinoma HepG2 cells.
Phytotherapy research : PTR 2007;21(1):52-7.
2006: Dong-Oh Moon; Sung-Yong Park; Moon-Soo Heo; Ki-Cheon Kim; Cheol Park; Woo Shin Ko; Yung Hyun Choi; Gi-Young Kim
Key regulators in bee venom-induced apoptosis are Bcl-2 and caspase-3 in human leukemic U937 cells through downregulation of ERK and Akt.
International immunopharmacology 2006;6(12):1796-807.
2006: Nam Deuk Kim; Eunok Im; Young Hyun Yoo; Yung Hyun Choi
Modulation of the cell cycle and induction of apoptosis in human cancer cells by synthetic bile acids.
Current cancer drug targets 2006;6(8):681-9.
2006: Cheng-Yun Jin; Yung Hyun Choi; Dong-Oh Moon; Cheol Park; Yeong-Min Park; Sang-Cheol Jeong; Moon-Soo Heo; Tae-Ho Lee; Jae-Dong Lee; Gi-Young Kim
Induction of G2/M arrest and apoptosis in human gastric epithelial AGS cells by aqueous extract of Agaricus blazei.
Oncology reports 2006;16(6):1349-55.
2006: Cheng-Yun Jin; Dong-Oh Moon; Kyeong-Jun Lee; Mun-Ok Kim; Jae-Dong Lee; Yung Hyun Choi; Yeong-Min Park; Gi-Young Kim
Piceatannol attenuates lipopolysaccharide-induced NF-kappaB activation and NF-kappaB-related proinflammatory mediators in BV2 microglia.
Pharmacological research : the official journal of the Italian Pharmacological Society 2006;54(6):461-7.
2006: Sung-Kwon Moon; Yung Hyun Choi; Cheorl-Ho Kim; Won-Seok Choi
p38MAPK mediates benzyl isothiocyanate-induced p21WAF1 expression in vascular smooth muscle cells via the regulation of Sp1.
Biochemical and biophysical research communications 2006;350(3):662-8.
2006: Yung Hyun Choi
Apoptosis of U937 human leukemic cells by sodium butyrate is associated with inhibition of telomerase activity.
International journal of oncology 2006;29(5):1207-13.
2006: Dong-Oh Moon; Cheng-Yun Jin; Jae-Dong Lee; Yung Hyun Choi; Soon-Cheol Ahn; Chang-Min Lee; Sang-Cheol Jeong; Yeong-Min Park; Gi-Young Kim
Curcumin decreases binding of Shiga-like toxin-1B on human intestinal epithelial cell line HT29 stimulated with TNF-alpha and IL-1beta: suppression of p38, JNK and NF-kappaB p65 as potential targets.
Biological & pharmaceutical bulletin 2006;29(7):1470-5.
2006: Yung Hyun Choi; Guang Hai Yan; Ok Hee Chai; Yung Hyun Choi; Xin Zhang; Jung Min Lim; Ji-Hyun Kim; Moo Sam Lee; Eui-Hyeog Han; Hyoung Tae Kim; Chang Ho Song
Inhibitory effects of Agaricus blazei on mast cell-mediated anaphylaxis-like reactions.
Biological & pharmaceutical bulletin 2006;29(7):1366-71.
2006: Cheol Park; Gi-Young Kim; Gun-Do Kim; Won Ho Lee; Jae Hun Cheong; Nam Deuk Kim; Song-Ja Bae; Jee H Jung; Yung Hyun Choi
Suppression of U937 human monocytic leukemia cell growth by dideoxypetrosynol A, a polyacetylene from the sponge Petrosia sp., via induction of Cdk inhibitor p16 and down-regulation of pRB phosphorylation.
Oncology reports 2006;16(1):171-6.
2006: Young-Ae Kim; Sun-Young Lim; Sook-Hee Rhee; Kun Young Park; Cheorl-Ho Kim; Byung Tae Choi; Su-Jun Lee; Yeong-Min Park; Yung Hyun Choi
Resveratrol inhibits inducible nitric oxide synthase and cyclooxygenase-2 expression in beta-amyloid-treated C6 glioma cells.
International journal of molecular medicine 2006;17(6):1069-75.
2006: Soo Young Jun; Yung Hyun Choi; Heung-Mook Shin
Siegesbeckia glabrescens induces apoptosis with different pathways in human MCF-7 and MDA-MB-231 breast carcinoma cells.
Oncology reports 2006;15(6):1461-7.
2006: Gi-Young Kim; Jae-Yoon Lee; Jeong-Ok Lee; Chung-Ho Ryu; Byung Tae Choi; Yong-Kee Jeong; Ki-Wan Lee; Sang-Chul Jeong; Yung Hyun Choi
Partial characterization and immunostimulatory effect of a novel polysaccharide-protein complex extracted from Phellinus linteus.
Bioscience, biotechnology, and biochemistry 2006;70(5):1218-26.
2006: Jun Hyuk Lee; Soo Jin Lee; Yung Hyun Choi; Kyung Tae Chung; Yong-Kee Jeong; Byung Tae Choi
Effects of mycelial culture of Phellinus linteus on ethanol-induced gastric ulcer in rats.
Phytotherapy research : PTR 2006;20(5):396-402.
2006: Cheol Park; Gi-Young Kim; Gun-Do Kim; Byung Tae Choi; Yeong-Min Park; Yung Hyun Choi
Induction of G2/M arrest and inhibition of cyclooxygenase-2 activity by curcumin in human bladder cancer T24 cells.
Oncology reports 2006;15(5):1225-31.
2006: Sun-Yong Baek; Su-Ryun Kim; Moon-Kyoung Bae; Jee-Won Hwang; Jeong-Sam Kim; Yung Hyun Choi; Hee-Jun Wee; Bong-Seon Kim; Jae-Bong Kim; Sik Yoon; Soo-Kyung Bae
Trichostatin A increases the thermosensitivity of human glioblastoma A172 cells.
Neuroscience letters 2006;396(3):230-4.
2006: J I Lee; D Y Choi; H S Chung; H G Seo; Hyun Joo Woo; Byung Tae Choi; Yung Hyun Choi
beta-lapachone induces growth inhibition and apoptosis in bladder cancer cells by modulation of Bcl-2 family and activation of caspases.
Experimental oncology 2006;28(1):30-5.
2006: Hye Joung Choi; Su-Bog Yee; Sang Eun Park; Eunok Im; Jee Hyung Jung; Hae Young Chung; Yung Hyun Choi; Nam Deuk Kim
Petrotetrayndiol A induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells through cytochrome c-mediated activation of caspases.
Cancer letters 2006;232(2):214-25.
2006: Gi-Young Kim; Woo Shin Ko; Jae-Yoon Lee; Jeong-Ok Lee; Chung-Ho Ryu; Byung Tae Choi; Yeong-Min Park; Yong-Kee Jeong; Kyeong-Jun Lee; Kwang-Sik Choi; Moon-Soo Heo; Yung Hyun Choi
Water extract of Cordyceps militaris enhances maturation of murine bone marrow-derived dendritic cells in vitro.
Biological & pharmaceutical bulletin 2006;29(2):354-60.
2006: Jun-Hyuk Lee; Kyung-Jeon Jang; Yong-Tae Lee; Yung Hyun Choi; Byung Tae Choi
Electroacupuncture inhibits inflammatory edema and hyperalgesia through regulation of cyclooxygenase synthesis in both peripheral and central nociceptive sites.
The American journal of Chinese medicine 2006;34(6):981-8.
2006: Hyun Joo Woo; Kun-Young Park; Chung-Ho Rhu; Won Ho Lee; Byung Tae Choi; Gi-Young Kim; Yeong-Min Park; Yung Hyun Choi
Beta-lapachone, a quinone isolated from Tabebuia avellanedae, induces apoptosis in HepG2 hepatoma cell line through induction of Bax and activation of caspase.
Journal of medicinal food 2006;9(2):161-8.
2006: Kyung Jin Woo; Jun Hee Lim; Seong-Il Suh; Young-Kyu Kwon; Sang-Woo Shin; Sang Chan Kim; Yung Hyun Choi; Jong-Wook Park; Taeg Kyu Kwon
Differential inhibitory effects of baicalein and baicalin on LPS-induced cyclooxygenase-2 expression through inhibition of C/EBPbeta DNA-binding activity.
Immunobiology 2006;211(5):359-68.
2005: Eunok Im; Sang-Ho Choi; Hongsuk Suh; Yung Hyun Choi; Young Hyun Yoo; Nam Deuk Kim
Synthetic bile acid derivatives induce apoptosis through a c-Jun N-terminal kinase and NF-kappaB-dependent process in human cervical carcinoma cells.
Cancer letters 2005;229(1):49-57.
2005: Hye Joung Choi; Yung Hyun Choi; Su-Bog Yee; Eunok Im; Jee Hyung Jung; Nam Deuk Kim
Ircinin-1 induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells.
Molecular carcinogenesis 2005;44(3):162-73.
2005: Gi-Young Kim; Moo-Yeol Lee; Hee-Jeong Lee; Dong-Oh Moon; Chang-Min Lee; Cheng-Yun Jin; Yung Hyun Choi; Yong-Kee Jeong; Kyung Tae Chung; Jae-Yun Lee; In-Hak Choi; Yeong-Min Park
Effect of water-soluble proteoglycan isolated from Agaricus blazei on the maturation of murine bone marrow-derived dendritic cells.
International immunopharmacology 2005;5(10):1523-32.
2005: Woo Shin Ko; Tae Yeol Park; Cheol Park; Young Hee Kim; Hwa Jung Yoon; Seung Yeon Lee; Sang Hoon Hong; Byung Tae Choi; Yong Tae Lee; Yung Hyun Choi
Induction of apoptosis by Chan Su, a traditional Chinese medicine, in human bladder carcinoma T24 cells.
Oncology reports 2005;14(2):475-80.
2005: Yung Hyun Choi
Induction of apoptosis by trichostatin A, a histone deacetylase inhibitor, is associated with inhibition of cyclooxygenase-2 activity in human non-small cell lung cancer cells.
International journal of oncology 2005;27(2):473-9.
2005: Jun-Hyuk Lee; Yung Hyun Choi; Byung Tae Choi
The anti-inflammatory effects of 2 Hz electroacupuncture with different intensities on acute carrageenan-induced inflammation in the rat paw.
International journal of molecular medicine 2005;16(1):99-102.
2005: Cheol Park; Sang Hoon Hong; Jae-Yun Lee; Gi-Young Kim; Byung Tae Choi; Yong Tea Lee; Dong Il Park; Yeong-Min Park; Yong-Kee Jeong; Yung Hyun Choi
Growth inhibition of U937 leukemia cells by aqueous extract of Cordyceps militaris through induction of apoptosis.
Oncology reports 2005;13(6):1211-6.
2005: Cheol Park; Byung Tae Choi; Kwang Il Kang; Taeg Kyu Kwon; JaeHun Cheong; Won Ho Lee; Nam Deuk Kim; Yung Hyun Choi
Induction of apoptosis and inhibition of cyclooxygenase-2 expression by N-methyl-N'-nitro-N-nitrosoguanidine in human leukemia cells.
Anti-cancer drugs 2005;16(5):507-13.
2005: Jae Hun Lee; JaeHun Cheong; Yeong-Min Park; Yung Hyun Choi
Down-regulation of cyclooxygenase-2 and telomerase activity by beta-lapachone in human prostate carcinoma cells.
Pharmacological research : the official journal of the Italian Pharmacological Society 2005;51(6):553-60.
2005: Youl-Nam Lee; Ha-Young Lee; Jae-Seok Kim; Cheol Park; Yung Hyun Choi; Taehoon G Lee; Sung Ho Ryu; Jong-Young Kwak; Yoe-Sik Bae
The novel phospholipase C activator, m-3M3FBS, induces monocytic leukemia cell apoptosis.
Cancer letters 2005;222(2):227-35.
2005: Dong Il Park; Jae Hun Lee; Sung-Kwon Moon; Cheorl-Ho Kim; Yong Tae Lee; JaeHun Cheong; Byung Tae Choi; Yung Hyun Choi
Induction of apoptosis and inhibition of telomerase activity by aqueous extract from Platycodon grandiflorum in human lung carcinoma cells.
Pharmacological research : the official journal of the Italian Pharmacological Society 2005;51(5):437-43.
2005: Ji-Cheon Jeong; Cheol-Ho Yoon; Woo-Hun Lee; Kwan-Kyu Park; Young-Chae Chang; Yung Hyun Choi; Cheorl-Ho Kim
Effects of Bambusae concretio Salicea (Chunchukhwang) on amyloid beta-induced cell toxicity and antioxidative enzymes in cultured rat neuronal astrocytes.
Journal of ethnopharmacology 2005;98(3):259-66.
2005: Hyun Joo Woo; Yung Hyun Choi
Growth inhibition of A549 human lung carcinoma cells by beta-lapachone through induction of apoptosis and inhibition of telomerase activity.
International journal of oncology 2005;26(4):1017-23.
2004: Hye Joung Choi; Song-Ja Bae; Nam Deuk Kim; Jee H Jung; Yung Hyun Choi
Induction of apoptosis by dideoxypetrosynol A, a polyacetylene from the sponge Petrosia sp., in human skin melanoma cells.
International journal of molecular medicine 2004;14(6):1091-6.
2004: Cheol Park; Byung Tae Choi; JaeHun Cheong; Sung-Kwon Moon; Cheorl-Ho Kim; Won Ho Lee; Yung Hyun Choi
Induction of apoptosis and G2/M arrest by N-methyl-N'-nitro-N-nitrosoguanidine in human prostate carcinoma cells.
Mutation research 2004;563(2):139-49.
2004: Sang Won Jung; Mi Hee Lee; Yong Chan Kim; Sang-Gi Paik; Yung Hyun Choi; Young Sang Kim; Kwang-il Kang
Modulation of the transactivation function of nuclear factor-kappaB by lipopolysaccharide in RAW264.7 macrophages.
International journal of oncology 2004;25(4):1081-7.
2004: Yung Hyun Choi; Man Kyu Huh; Chung-Ho Ryu; Byung Tae Choi; Yong-Kee Jeong
Induction of apoptotic cell death by mycelium extracts of Phellinus linteus in human neuroblastoma cells.
International journal of molecular medicine 2004;14(2):227-32.
2004: Sang Eun Park; Hye Joung Choi; Su-Bog Yee; Hae Young Chung; Hongsuk Suh; Yung Hyun Choi; Young Hyun Yoo; Nam Deuk Kim
Synthetic bile acid derivatives inhibit cell proliferation and induce apoptosis in HT-29 human colon cancer cells.
International journal of oncology 2004;25(1):231-6.
2004: Jun-Hyuk Lee; Yung Hyun Choi; Ho-Sung Kang; Byung Tae Choi
An aqueous extract of Platycodi radix inhibits LPS-induced NF-kappaB nuclear translocation in human cultured airway epithelial cells.
International journal of molecular medicine 2004;13(6):843-7.
2004: Dong Il Park; Hae-Yun Choi; Chul Woo Kam; Cheol Park; Tae Hyun Choi; Won Ho Lee; Yung Hyun Choi
Wikyungtang inhibits proliferation of A549 human lung cancer cells via inducing apoptosis and suppressing cyclooxygenase-2 activity.
Oncology reports 2004;11(4):853-6.
2004: Young-Ae Kim; Byung Tae Choi; Yong Tae Lee; Dong Il Park; Sook-Hee Rhee; Kun-Young Park; Yung Hyun Choi
Resveratrol inhibits cell proliferation and induces apoptosis of human breast carcinoma MCF-7 cells.
Oncology reports 2004;11(2):441-6.
2004: Sung-Kwon Moon; Sun-Young Jung; Yung Hyun Choi; Young-Choon Lee; Winston Patterson; Cheorl-Ho Kim
PDTC, metal chelating compound, induces G1 phase cell cycle arrest in vascular smooth muscle cells through inducing p21Cip1 expression: involvement of p38 mitogen activated protein kinase.
Journal of cellular physiology 2004;198(2):310-23.
2003: Yung Hyun Choi; Kyu Ri Kong; Young-Ae Kim; KEUN JUNG; Jeong-Ha Kil; Sook-Hee Rhee; Kun-Young Park
Induction of Bax and activation of caspases during beta-sitosterol-mediated apoptosis in human colon cancer cells.
International journal of oncology 2003;23(6):1657-62.
2003: Byung Tae Choi; JaeHun Cheong; Yung Hyun Choi
beta-Lapachone-induced apoptosis is associated with activation of caspase-3 and inactivation of NF-kappaB in human colon cancer HCT-116 cells.
Anti-cancer drugs 2003;14(10):845-50.
2003: Young-Ae Kim; Won Ho Lee; Tae Hyun Choi; Sook-Hee Rhee; Kun-Young Park; Yung Hyun Choi
Involvement of p21WAF1/CIP1, pRB, Bax and NF-kappaB in induction of growth arrest and apoptosis by resveratrol in human lung carcinoma A549 cells.
International journal of oncology 2003;23(4):1143-9.
2003: Sung-Kwon Moon; Sun-Young Jung; Yung Hyun Choi; Young-Choon Lee; Cheorl-Ho Kim
Platelet-derived growth factor induces p21/WAF1 promoter in vascular smooth muscle cells via activation of an Sp1 site.
FEBS letters 2003;552(2-3):130-4.
2003: Yung Hyun Choi; Eun Ok Im; Hongsuk Suh; Youngeup Jin; Young Hyun Yoo; Nam Deuk Kim
Apoptosis and modulation of cell cycle control by synthetic derivatives of ursodeoxycholic acid and chenodeoxycholic acid in human prostate cancer cells.
Cancer letters 2003;199(2):157-67.
2003: Jeum Soon Bae; Moon Kyoo Jang; SunHwa Hong; Won Gun An; Yung Hyun Choi; Han Do Kim; JaeHun Cheong
Phosphorylation of NF-kappa B by calmodulin-dependent kinase IV activates anti-apoptotic gene expression.
Biochemical and biophysical research communications 2003;305(4):1094-8.
2003: Sang Hwa Yang; Jong Sik Kim; Tae Jeong Oh; Myung Soon Kim; Sun Woo Lee; Suk Kyung Woo; Hyun Sill Cho; Yung Hyun Choi; Young Ho Kim; Sun Young Rha; Hyun Cheol Chung; Sung Whan An
Genome-scale analysis of resveratrol-induced gene expression profile in human ovarian cancer cells using a cDNA microarray.
International journal of oncology 2003;22(4):741-50.
2003: Yung Hyun Choi; Ho Sung Kang; Mi-Ae Yoo
Suppression of human prostate cancer cell growth by beta-lapachone via down-regulation of pRB phosphorylation and induction of Cdk inhibitor p21(WAF1/CIP1).
Journal of biochemistry and molecular biology 2003;36(2):223-9.
2003: Kun-Young Park; KEUN JUNG; Sook-Hee Rhee; Yung Hyun Choi
Antimutagenic effects of doenjang (Korean fermented soypaste) and its active compounds.
Mutation research 2003;523-524():43-53.
2003: Byung Tae Choi; Jun-Hyuk Lee; Woo Shin Ko; Young-Hee Kim; Yung Hyun Choi; Ho-Sung Kang; Han Do Kim
Anti-inflammatory effects of aqueous extract from Dichroa febrifuga root in rat liver.
Acta pharmacologica Sinica 2003;24(2):127-32.
2003: Young-Ae Kim; Sook-Hee Rhee; Kun-Young Park; Yung Hyun Choi
Antiproliferative effect of resveratrol in human prostate carcinoma cells.
Journal of medicinal food 2003;6(4):273-80.
2002: Min Young Lee; Che-Hun Jung; Keesook Lee; Yung Hyun Choi; SunHwa Hong; JaeHun Cheong
Activating transcription factor-2 mediates transcriptional regulation of gluconeogenic gene PEPCK by retinoic acid.
Diabetes 2002;51(12):3400-7.
2002: Yung Hyun Choi; Mi Jung Kim; Seung Yeon Lee; Youl-Nam Lee; Gyoo Yong Chi; Hyun Sup Eom; Nam Deuk Kim; Byung Tae Choi
Phosphorylation of p53, induction of Bax and activation of caspases during beta-lapachone-mediated apoptosis in human prostate epithelial cells.
International journal of oncology 2002;21(6):1293-9.
2002: Jun Hyuk Lee; Gyung Hwa Kang; Kyung Chul Kim; Kyoung Mi Kim; Dong Il Park; Byung Tae Choi; Ho Sung Kang; Yong Tae Lee; Yung Hyun Choi
Tetrandrine-induced cell cycle arrest and apoptosis in A549 human lung carcinoma cells.
International journal of oncology 2002;21(6):1239-44.
2002: Mi Nam Lee; Eun Young Jung; Hyun Jin Kwun; Hong Ki Jun; Dae-Yeul Yu; Yung Hyun Choi; Kyung Lib Jang
Hepatitis C virus core protein represses the p21 promoter through inhibition of a TGF-beta pathway.
The Journal of general virology 2002;83(Pt 9):2145-51.
2002: Ramon G Manzano; Luis M Montuenga; Mark Dayton; Paul Dent; Ichiro Kinoshita; Silvestre Vicent; Ginger J Gardner; Phuongmai Nguyen; Yung Hyun Choi; Jane Trepel; Nelly Auersperg; Michael J Birrer
CL100 expression is down-regulated in advanced epithelial ovarian cancer and its re-expression decreases its malignant potential.
Oncogene 2002;21(28):4435-47.
2002: Youn Wook Chung; Dae-won Jeong; Joo Yun Won; Eui-Ju Choi; Yung Hyun Choi; Ick Young Kim
H(2)O(2)-induced AP-1 activation and its effect on p21(WAF1/CIP1)-mediated G2/M arrest in a p53-deficient human lung cancer cell.
Biochemical and biophysical research communications 2002;293(4):1248-53.
2002: Song Iy Han; Su Young Oh; Won Je Jeon; Jung Mo Kim; Jun Hyuk Lee; Hae Young Chung; Yung Hyun Choi; Mi-Ae Yoo; Han Do Kim; Ho Sung Kang
Mild heat shock induces cyclin D1 synthesis through multiple Ras signal pathways.
FEBS letters 2002;515(1-3):141-5.
2002: Nam Deuk Kim; Eun Ok Im; Yung Hyun Choi; Young Hyun Yoo
Synthetic bile acids: novel mediators of apoptosis.
Journal of biochemistry and molecular biology 2002;35(1):134-41.
2002: Eun-Jin Oh; Jae-Hong Park; Mong Cho; Won-Jae Lee; Yung Hyun Choi; Mi-Ae Yoo
The caudal-related homeodomain protein CDX1 activates proliferating cell nuclear antigen expression in hepatocellular and colorectal carcinoma cells.
International journal of oncology 2002;20(1):23-9.
2001: Yung Hyun Choi
Proteasome-mediated degradation of BRCA1 protein in MCF-7 human breast cancer cells.
International journal of oncology 2001;19(4):687-93.
2001: Yung Hyun Choi; Byung Tae Choi; W H Lee; S H Rhee; Kun-Young Park
Doenjang hexane fraction-induced G1 arrest is associated with the inhibition of pRB phosphorylation and induction of Cdk inhibitor p21 in human breast carcinoma MCF-7 cells.
Oncology reports 2001;8(5):1091-6.
2001: Jae-Hong Park; Eun-Jin Oh; Yung Hyun Choi; Chi-Dug Kang; Ho Sung Kang; Dong-Kyoo Kim; KI Kang; Mi-Ae Yoo
Synergistic effects of dexamethasone and genistein on the expression of Cdk inhibitor p21WAF1/CIP1 in human hepatocellular and colorectal carcinoma cells.
International journal of oncology 2001;18(5):997-1002.
2001: Yung Hyun Choi; E O Im; Hongsuk Suh; Youngeup Jin; W H Lee; Y H Yoo; K W Kim; Nam Deuk Kim
Apoptotic activity of novel bile acid derivatives in human leukemic T cells through the activation of caspases.
International journal of oncology 2001;18(5):979-84.
2001: E O Im; Yung Hyun Choi; KJ Paik; Hongsuk Suh; Youngeup Jin; Kyu-Won Kim; Young Hyun Yoo; Nam Deuk Kim
Novel bile acid derivatives induce apoptosis via a p53-independent pathway in human breast carcinoma cells.
Cancer letters 2001;163(1):83-93.
2000: Sang-Ho Choi; H K Kang; E O Im; Yung-Jin Kim; Young-Tae Bae; Yung Hyun Choi; K H Lee; Hae Young Chung; H K Chang; Nam Deuk Kim
Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by retinoic acids.
International journal of oncology 2000;17(5):971-6.
2000: Yung Hyun Choi; Jin Hyen Baek; M A Yoo; H Y Chung; Nam Deuk Kim; K W Kim
Induction of apoptosis by ursolic acid through activation of caspases and down-regulation of c-IAPs in human prostate epithelial cells.
International journal of oncology 2000;17(3):565-71.
2000: Yung Hyun Choi; Won Ho Lee; Kun-Young Park; L Zhang
p53-independent induction of p21 (WAF1/CIP1), reduction of cyclin B1 and G2/M arrest by the isoflavone genistein in human prostate carcinoma cells.
Japanese journal of cancer research : Gann 2000;91(2):164-73.
1999: J S Jang; Yung Hyun Choi
Proteolytic degradation of the retinoblastoma family protein p107: A putative cooperative role of calpain and proteasome.
International journal of molecular medicine 1999;4(5):487-92.
1999: HR Kim; C H Lee; Yung Hyun Choi; Ho Sung Kang; Han Do Kim
Geldanamycin induces cell cycle arrest in K562 erythroleukemic cells.
IUBMB life 1999;48(4):425-8.
1999: M Oh; Yung Hyun Choi; S Choi; H Chung; K Kim; SI Kim; Dong-Kyoo Kim; Nam Deuk Kim
Anti-proliferating effects of ginsenoside Rh2 on MCF-7 human breast cancer cells.
International journal of oncology 1999;14(5):869-75.