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Nagesh Chopra

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TOP 3
Nagesh Chopra; Björn C Knollmann
Triadin regulates cardiac muscle couplon structure and microdomain Ca(2+) signalling: a path towards ventricular arrhythmias.
Hiroshi Watanabe; Tao Yang; Dina Myers Stroud; Naohito Tanabe; Dao W Wang; Thomas C Atack; Nagesh Chopra; Alfred L George; Lynn Hall; Louise Harris; Susan B Hipkens; Björn C Knollmann; Sabina Kupershmidt; Brenda Leake; John S Lowe; Mark Magnuson; Dan Mark Roden
Striking In vivo phenotype of a disease-associated human SCN5A mutation producing minimal changes in vitro.
Nagesh Chopra; Tao Yang; Parisa Asghari; Edwin D Moore; Sabine Huke; Brandy Akin; Robert A Cattolica; Claudio F Perez; Thinn Hlaing; Barbara E C Knollmann-Ritschel; Larry R Jones; Isaac N Pessah; Paul D Allen; Clara Franzini-Armstrong; Björn C Knollmann
Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias.

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All Publications

2013: Nagesh Chopra; Björn C Knollmann
Triadin regulates cardiac muscle couplon structure and microdomain Ca(2+) signalling: a path towards ventricular arrhythmias.
Cardiovascular research 2013;98(2):187-91.
2011: Hiroshi Watanabe; Tao Yang; Dina Myers Stroud; Naohito Tanabe; Dao W Wang; Thomas C Atack; Nagesh Chopra; Alfred L George; Lynn Hall; Louise Harris; Susan B Hipkens; Björn C Knollmann; Sabina Kupershmidt; Brenda Leake; John S Lowe; Mark Magnuson; Dan Mark Roden
Striking In vivo phenotype of a disease-associated human SCN5A mutation producing minimal changes in vitro.
Circulation 2011;124(9):1001-11.
2009: Nagesh Chopra; Tao Yang; Parisa Asghari; Edwin D Moore; Sabine Huke; Brandy Akin; Robert A Cattolica; Claudio F Perez; Thinn Hlaing; Barbara E C Knollmann-Ritschel; Larry R Jones; Isaac N Pessah; Paul D Allen; Clara Franzini-Armstrong; Björn C Knollmann
Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(18):7636-41.
2009: Hiroshi Watanabe; Nagesh Chopra; Derek Laver; Hyun Seok Hwang; Sean S Davies; Daniel E Roach; Henry J Duff; Dan Mark Roden; Arthur A M Wilde; Björn C Knollmann
Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans.
Nature medicine 2009;15(4):380-3.
2007: Nagesh Chopra; Prince J Kannankeril; Tao Yang; Thinn Hlaing; Izabela Holinstat; Kristen Ettensohn; Karl Pfeifer; Brandy Akin; Larry R Jones; Clara Franzini-Armstrong; Björn C Knollmann
Modest reductions of cardiac calsequestrin increase sarcoplasmic reticulum Ca2+ leak independent of luminal Ca2+ and trigger ventricular arrhythmias in mice.
Circulation research 2007;101(6):617-26.
2006: Kai Liu; Susan Hipkens; Tao Yang; Robert Abraham; Wei Zhang; Nagesh Chopra; Björn C Knollmann; Mark Magnuson; Dan Mark Roden
Recombinase-mediated cassette exchange to rapidly and efficiently generate mice with human cardiac sodium channels.
Genesis (New York, N.Y. : 2000) 2006;44(11):556-64.
2006: Björn C Knollmann; Nagesh Chopra; Thinn Hlaing; Brandy Akin; Tao Yang; Kristen Ettensohn; Barbara E C Knollmann; Kenneth D Horton; Neil J Weissman; Izabela Holinstat; Wei Zhang; Dan Mark Roden; Larry R Jones; Clara Franzini-Armstrong; Karl Pfeifer
Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia.
The Journal of clinical investigation 2006;116(9):2510-20.