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Pankaj Chopra

Research Profile

Chemicals & Drugs

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Publications

TOP 3
Tadas S Vasaitis; Aashvini Belosay; Adam Schayowitz; Aakanksha Khandelwal; Pankaj Chopra; Lalji Gediya; Zhiyong Guo; Hongbin Fang; Vincent Njar; Angela Brodie
Androgen receptor inactivation contributes to antitumor efficacy of 17{alpha}-hydroxylase/17,20-lyase inhibitor 3beta-hydroxy-17-(1H-benzimidazole-1-yl)androsta-5,16-diene in prostate cancer.
Jyoti B Patel; Aakanksha Khandelwal; Pankaj Chopra; Venkatesh D Handratta; Vincent Njar
Murine toxicology and pharmacokinetics of novel retinoic acid metabolism blocking agents.
Puranik Purushottamachar; Aakanksha Khandelwal; Pankaj Chopra; Neha Maheshwari; Lalji Gediya; Tadas S Vasaitis; Robert D Bruno; Omoshile O Clement; Vincent Njar
First pharmacophore-based identification of androgen receptor down-regulating agents: discovery of potent anti-prostate cancer agents.

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All Publications

2008: Tadas S Vasaitis; Aashvini Belosay; Adam Schayowitz; Aakanksha Khandelwal; Pankaj Chopra; Lalji Gediya; Zhiyong Guo; Hongbin Fang; Vincent Njar; Angela Brodie
Androgen receptor inactivation contributes to antitumor efficacy of 17{alpha}-hydroxylase/17,20-lyase inhibitor 3beta-hydroxy-17-(1H-benzimidazole-1-yl)androsta-5,16-diene in prostate cancer.
Molecular cancer therapeutics 2008;7(8):2348-57.
2007: Jyoti B Patel; Aakanksha Khandelwal; Pankaj Chopra; Venkatesh D Handratta; Vincent Njar
Murine toxicology and pharmacokinetics of novel retinoic acid metabolism blocking agents.
Cancer chemotherapy and pharmacology 2007;60(6):899-905.
2007: Puranik Purushottamachar; Aakanksha Khandelwal; Pankaj Chopra; Neha Maheshwari; Lalji Gediya; Tadas S Vasaitis; Robert D Bruno; Omoshile O Clement; Vincent Njar
First pharmacophore-based identification of androgen receptor down-regulating agents: discovery of potent anti-prostate cancer agents.
Bioorganic & medicinal chemistry 2007;15(10):3413-21.
2006: Vincent Njar; Lalji Gediya; Puranik Purushottamachar; Pankaj Chopra; Aashvini Belosay; Jyoti B Patel
Retinoids in clinical use.
Medicinal chemistry (Shāriqah (United Arab Emirates)) 2006;2(4):431-8.
2006: Vincent Njar; Lalji Gediya; Puranik Purushottamachar; Pankaj Chopra; Tadas S Vasaitis; Aakanksha Khandelwal; Jhalak Mehta; Carlic K Huynh; Aashvini Belosay; Jyoti B Patel
Retinoic acid metabolism blocking agents (RAMBAs) for treatment of cancer and dermatological diseases.
Bioorganic & medicinal chemistry 2006;14(13):4323-40.
2005: Lalji Gediya; Pankaj Chopra; Puranik Purushottamachar; Neha Maheshwari; Vincent Njar
A new simple and high-yield synthesis of suberoylanilide hydroxamic acid and its inhibitory effect alone or in combination with retinoids on proliferation of human prostate cancer cells.
Journal of medicinal chemistry 2005;48(15):5047-51.
2005: Venkatesh D Handratta; Tadas S Vasaitis; Vincent Njar; Lalji Gediya; Ritesh Kataria; Pankaj Chopra; Donnell Newman; Rena Farquhar; Zhiyong Guo; Yun Qiu; Angela Brodie
Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model.
Journal of medicinal chemistry 2005;48(8):2972-84.