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Erik Christensen

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Simon Glerup; Camilla Gustafsen; Anders Hay-Schmidt; Mads Kjolby; Maria Lume; Peder Madsen; Jens R Nyengaard; Anders Nykjaer; Ditte Olsen; Dirk Bender; Erik I Christensen; Mart Saarma; Christian Vaegter; Claus M Petersen
SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET.
Kathrin Weyer; Erik I Christensen; Rikke Nielsen; Steen V Petersen; Michael Rehling; Henrik Birn
Renal uptake of 99mTc-dimercaptosuccinic acid is dependent on normal proximal tubule receptor-mediated endocytosis.
Erik I Christensen; Tina Storm; Kathrin Weyer; Henrik Birn; Rikke Nielsen
Endocytic receptors in the renal proximal tubule.

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2013: Simon Glerup; Camilla Gustafsen; Anders Hay-Schmidt; Mads Kjolby; Maria Lume; Peder Madsen; Jens R Nyengaard; Anders Nykjaer; Ditte Olsen; Dirk Bender; Erik I Christensen; Mart Saarma; Christian Vaegter; Claus M Petersen
SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET.
Cell reports 2013;3(1):186-99.
2013: Kathrin Weyer; Erik I Christensen; Rikke Nielsen; Steen V Petersen; Michael Rehling; Henrik Birn
Renal uptake of 99mTc-dimercaptosuccinic acid is dependent on normal proximal tubule receptor-mediated endocytosis.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2013;54(1):159-65.
2012: Erik I Christensen; Tina Storm; Kathrin Weyer; Henrik Birn; Rikke Nielsen
Endocytic receptors in the renal proximal tubule.
Physiology (Bethesda, Md.) 2012;27(4):223-36.
2012: Kathrin Weyer; Erik I Christensen; Rikke Nielsen; Henrik Birn
Generation of urinary albumin fragments does not require proximal tubular uptake.
Journal of the American Society of Nephrology : JASN 2012;23(4):591-6.
2012: Thaneas Prabakaran; Simon C Satchell; Søren S Sørensen; Ulla Feldt-Rasmussen; Peter W Mathieson; Rikke Nielsen; Erik I Christensen
Mannose 6-phosphate receptor and sortilin mediated endocytosis of α-galactosidase A in kidney endothelial cells.
PloS one 2012;7(6):e39975.
2011: Kathrin Weyer; Erik I Christensen; Renata Kozyraki; Jingdong Shan; Tina Storm; Seppo Vainio; Pierre J Verroust; Rikke Nielsen
Mouse model of proximal tubule endocytic dysfunction.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011;26(11):3446-51.
2011: Thaneas Prabakaran; Moin A Saleem; Søren S Sørensen; Pierre J Verroust; Ulla Feldt-Rasmussen; Jakob V Larsen; Rikke Nielsen; Claus M Petersen; Erik I Christensen
Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease.
PloS one 2011;6(9):e25065.
2010: Sabine Amsellem; Jakub Gburek; Ghislaine Hamard; Rikke Nielsen; Thomas E Willnow; Olivier Devuyst; Ebba Nexo; Pierre J Verroust; Erik I Christensen; Renata Kozyraki
Cubilin is essential for albumin reabsorption in the renal proximal tubule.
Journal of the American Society of Nephrology : JASN 2010;21(11):1859-67.
2010: Wânia R Lima; Kleber S Parreira; Olivier Devuyst; Adrian Caplanusi; Francisca N'Kuli; Benoit Marien; Patrick Van Der Smissen; Pedro M S Alves; Pierre J Verroust; Erik I Christensen; Fabiola Terzi; Karl Matter; Maria S Balda; Christophe E Pierreux; Pierre J Courtoy
ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells.
Journal of the American Society of Nephrology : JASN 2010;21(3):478-88.
2009: Erik I Christensen; Pierre J Verroust; Rikke Nielsen
Receptor-mediated endocytosis in renal proximal tubule.
Pflügers Archiv : European journal of physiology 2009;458(6):1039-48.
2008: Erik I Christensen; Pierre J Verroust
Interstitial fibrosis: tubular hypothesis versus glomerular hypothesis.
Kidney international 2008;74(10):1233-6.
2008: Erik I Christensen; Daniela Raciti; Luca Reggiani; Pierre J Verroust; André W Brändli
Gene expression analysis defines the proximal tubule as the compartment for endocytic receptor-mediated uptake in the Xenopus pronephric kidney.
Pflügers Archiv : European journal of physiology 2008;456(6):1163-76.
2007: Xiao-Yue Zhai; Robert A Fenton; Arne Andreasen; Jesper Skovhus Thomsen; Erik I Christensen
Aquaporin-1 is not expressed in descending thin limbs of short-loop nephrons.
Journal of the American Society of Nephrology : JASN 2007;18(11):2937-44.
2007: Erik I Christensen; Henrik Birn; B Rippe; Arvid B Maunsbach
Controversies in nephrology: renal albumin handling, facts, and artifacts!
Kidney international 2007;72(10):1192-4.
2007: Xiao-Yue Zhai; I B Kristoffersen; Erik I Christensen
Immunocytochemistry of renal membrane proteins on epoxy sections.
Kidney international 2007;72(6):731-5.
2007: Rikke Nielsen; Pierre J Courtoy; Christian Jacobsen; Geneviève Dom; Wânia Rezende Lima; Michel Jadot; Thomas E Willnow; Olivier Devuyst; Erik I Christensen
Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(13):5407-12.
2007: Erik I Christensen; Qun Zhou; Søren S Sørensen; Ase Krogh Rasmussen; Christian Jacobsen; Ulla Feldt-Rasmussen; Rikke Nielsen
Distribution of alpha-galactosidase A in normal human kidney and renal accumulation and distribution of recombinant alpha-galactosidase A in Fabry mice.
Journal of the American Society of Nephrology : JASN 2007;18(3):698-706.
2007: Erik I Christensen; Rikke Nielsen
Role of megalin and cubilin in renal physiology and pathophysiology.
Reviews of physiology, biochemistry and pharmacology 2007;158():1-22.
2006: Xiao-Yue Zhai; Erik I Christensen; Arne Andreasen
Low noise electron microscopy by merging multiple images digitized from conventional films with reference to the mouse kidney.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 2006;12(3):255-61.
2006: Marouan Abouhamed; Jakub Gburek; Wei Liu; Blazej Torchalski; Andreas Wilhelm; Natascha A Wolff; Erik I Christensen; Frank Thévenod; Craig P Smith
Divalent metal transporter 1 in the kidney proximal tubule is expressed in late endosomes/lysosomal membranes: implications for renal handling of protein-metal complexes.
American journal of physiology. Renal physiology 2006;290(6):F1525-33.
2006: K Thelle; Erik I Christensen; Henrik Vorum; Hans Ørskov; Henrik Birn
Characterization of proteinuria and tubular protein uptake in a new model of oral L-lysine administration in rats.
Kidney international 2006;69(8):1333-40.
2006: Henrik Birn; Erik I Christensen
Renal albumin absorption in physiology and pathology.
Kidney international 2006;69(3):440-9.
2006: Xiao-Yue Zhai; Jesper Skovhus Thomsen; Henrik Birn; Inger B Kristoffersen; Arne Andreasen; Erik I Christensen
Three-dimensional reconstruction of the mouse nephron.
Journal of the American Society of Nephrology : JASN 2006;17(1):77-88.
2005: Henrik Birn; Xiao-Yue Zhai; Jan Holm; Steen Ingemann Hansen; Christian Jacobsen; Erik I Christensen; Søren K Moestrup
Megalin binds and mediates cellular internalization of folate binding protein.
The FEBS journal 2005;272(17):4423-30.
2005: J Nagai; Erik I Christensen; S M Morris; Thomas E Willnow; J A Cooper; Rikke Nielsen
Mutually dependent localization of megalin and Dab2 in the renal proximal tubule.
American journal of physiology. Renal physiology 2005;289(3):F569-76.
2005: Qianchuan He; Mette Madsen; Adam Kilkenney; Brittany L Gregory; Erik I Christensen; Henrik Vorum; Peter Højrup; Alejandro A Schäffer; Ewen F Kirkness; Stephan M Tanner; Albert de La Chapelle; Urs Giger; Søren K Moestrup; John C Fyfe
Amnionless function is required for cubilin brush-border expression and intrinsic factor-cobalamin (vitamin B12) absorption in vivo.
Blood 2005;106(4):1447-53.
2005: Sharmila Fagoonee; Jakub Gburek; Emilio Hirsch; Samuele Marro; Søren K Moestrup; Jacob M Laurberg; Erik I Christensen; Lorenzo Silengo; Fiorella Altruda; Emanuela Tolosano
Plasma protein haptoglobin modulates renal iron loading.
The American journal of pathology 2005;166(4):973-83.
2005: Henrik Birn; Ofer Spiegelstein; Erik I Christensen; Richard Finnell
Renal tubular reabsorption of folate mediated by folate binding protein 1.
Journal of the American Society of Nephrology : JASN 2005;16(3):608-15.
2005: Yves Allory; Yasuko Matsuoka; Céline Bazille; Erik I Christensen; Pierre Ronco; Hanna Debiec
The L1 cell adhesion molecule is induced in renal cancer cells and correlates with metastasis in clear cell carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(3):1190-7.
2005: Yoshio Ohno; Henrik Birn; Erik I Christensen
In vivo confocal laser scanning microscopy and micropuncture in intact rat.
Nephron. Experimental nephrology 2005;99(1):e17-25.
2004: Erik I Christensen; Jakub Gburek
Protein reabsorption in renal proximal tubule-function and dysfunction in kidney pathophysiology.
Pediatric nephrology (Berlin, Germany) 2004;19(7):714-21.
2004: John C Fyfe; Mette Madsen; Peter Højrup; Erik I Christensen; Stephan M Tanner; Albert de La Chapelle; Qianchuan He; Søren K Moestrup
The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless.
Blood 2004;103(5):1573-9.
2003: Michael Gekle; Petra Knaus; Rikke Nielsen; Sigrid Mildenberger; Ruth Freudinger; Verena Wohlfarth; Christoph Sauvant; Erik I Christensen
Transforming growth factor-beta1 reduces megalin- and cubilin-mediated endocytosis of albumin in proximal-tubule-derived opossum kidney cells.
The Journal of physiology 2003;552(Pt 2):471-81.
2003: Jakub Gburek; Henrik Birn; Pierre J Verroust; Bogusława Goj; Christian Jacobsen; Søren K Moestrup; Thomas E Willnow; Erik I Christensen
Renal uptake of myoglobin is mediated by the endocytic receptors megalin and cubilin.
American journal of physiology. Renal physiology 2003;285(3):F451-8.
2003: Erik I Christensen; Olivier Devuyst; Geneviève Dom; Rikke Nielsen; Patrick Van Der Smissen; Pierre J Verroust; Michèle Leruth; William B Guggino; Pierre J Courtoy
Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(14):8472-7.
2003: Henrik Birn; Ebba Nexø; Erik I Christensen; Rikke Nielsen
Diversity in rat tissue accumulation of vitamin B12 supports a distinct role for the kidney in vitamin B12 homeostasis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(6):1095-100.
2003: Xiao-Yue Zhai; Henrik Birn; Kim Bak Jensen; Jesper Skovhus Thomsen; Arne Andreasen; Erik I Christensen
Digital three-dimensional reconstruction and ultrastructure of the mouse proximal tubule.
Journal of the American Society of Nephrology : JASN 2003;14(3):611-9.
2002: Erik I Christensen; Pierre J Verroust
Megalin and cubilin, role in proximal tubule function and during development.
Pediatric nephrology (Berlin, Germany) 2002;17(12):993-9.
2002: Pierre J Verroust; Erik I Christensen
Megalin and cubilin--the story of two multipurpose receptors unfolds.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17(11):1867-71.
2002: Michael Gekle; Oscar K Serrano; Karina Drumm; Sigrid Mildenberger; Ruth Freudinger; Birgit Gassner; Hans Willi Jansen; Erik I Christensen
NHE3 serves as a molecular tool for cAMP-mediated regulation of receptor-mediated endocytosis.
American journal of physiology. Renal physiology 2002;283(3):F549-58.
2002: Pierre J Verroust; Henrik Birn; Rikke Nielsen; Renata Kozyraki; Erik I Christensen
The tandem endocytic receptors megalin and cubilin are important proteins in renal pathology.
Kidney international 2002;62(3):745-56.
2002: Erik I Christensen; Henrik Birn
Megalin and cubilin: multifunctional endocytic receptors.
Nature reviews. Molecular cell biology 2002;3(4):256-66.
2002: Henrik Birn; Thomas E Willnow; Rikke Nielsen; Anthony G W Norden; Christian Bönsch; Søren K Moestrup; Ebba Nexø; Erik I Christensen
Megalin is essential for renal proximal tubule reabsorption and accumulation of transcobalamin-B(12).
American journal of physiology. Renal physiology 2002;282(3):F408-16.
2002: Jakub Gburek; Pierre J Verroust; Thomas E Willnow; John C Fyfe; Wojciech Nowacki; Christian Jacobsen; Søren K Moestrup; Erik I Christensen
Megalin and cubilin are endocytic receptors involved in renal clearance of hemoglobin.
Journal of the American Society of Nephrology : JASN 2002;13(2):423-30.
2002: Christian Schmitz; Jan Hilpert; Christian Jacobsen; Christian Boensch; Erik I Christensen; Friedrich C Luft; Thomas E Willnow
Megalin deficiency offers protection from renal aminoglycoside accumulation.
The Journal of biological chemistry 2002;277(1):618-22.
2002: Erik I Christensen
Pathophysiology of protein and vitamin handling in the proximal tubule.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17 Suppl 9():57-8.
2001: Anders Nykjaer; John C Fyfe; Renata Kozyraki; Jörg R Leheste; Christian Jacobsen; Morten S Nielsen; Pierre J Verroust; Maria Aminoff; Albert de La Chapelle; Søren K Moestrup; R Ray; Jørgen Gliemann; Thomas E Willnow; Erik I Christensen
Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3).
Proceedings of the National Academy of Sciences of the United States of America 2001;98(24):13895-900.
2001: Renata Kozyraki; John C Fyfe; Pierre J Verroust; Christian Jacobsen; A Dautry-Varsat; Jakub Gburek; Thomas E Willnow; Erik I Christensen; Søren K Moestrup
Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(22):12491-6.
2001: Rikke Nielsen; Boe Sandahl Sorensen; Henrik Birn; Erik I Christensen; Ebba Nexø
Transcellular transport of vitamin B(12) in LLC-PK1 renal proximal tubule cells.
Journal of the American Society of Nephrology : JASN 2001;12(6):1099-106.
2001: Morten S Nielsen; Peder Madsen; Erik I Christensen; Anders Nykjaer; Jørgen Gliemann; D Kasper; Regina Pohlmann; Claus M Petersen
The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein.
The EMBO journal 2001;20(9):2180-90.
2001: R Burmeister; Inger-Margrethe Boe; Anders Nykjaer; Christian Jacobsen; S K Moestrup; Pierre J Verroust; Erik I Christensen; Johan Lund; Thomas E Willnow
A two-receptor pathway for catabolism of Clara cell secretory protein in the kidney.
The Journal of biological chemistry 2001;276(16):13295-301.
2001: Erik I Christensen; Henrik Birn
Megalin and cubilin: synergistic endocytic receptors in renal proximal tubule.
American journal of physiology. Renal physiology 2001;280(4):F562-73.
2000: Mónica Mendes Sousa; Anthony G W Norden; C Jacobsen; Thomas E Willnow; Erik I Christensen; Rajesh V Thakker; Pierre J Verroust; Søren K Moestrup; Maria João Saraiva
Evidence for the role of megalin in renal uptake of transthyretin.
The Journal of biological chemistry 2000;275(49):38176-81.
2000: Xiao-Yue Zhai; Rikke Nielsen; Henrik Birn; Karina Drumm; Sigrid Mildenberger; Ruth Freudinger; Søren K Moestrup; Pierre J Verroust; Erik I Christensen; Michael Gekle
Cubilin- and megalin-mediated uptake of albumin in cultured proximal tubule cells of opossum kidney.
Kidney international 2000;58(4):1523-33.
2000: C Schmitz; Michael Gotthardt; S Hinderlich; Jörg R Leheste; V Gross; Henrik Vorum; Erik I Christensen; Friedrich C Luft; S Takahashi; Thomas E Willnow
Normal blood pressure and plasma renin activity in mice lacking the renin-binding protein, a cellular renin inhibitor.
The Journal of biological chemistry 2000;275(20):15357-62.
2000: Henrik Birn; John C Fyfe; Christian Jacobsen; F Mounier; Pierre J Verroust; H Orskov; Thomas E Willnow; Søren K Moestrup; Erik I Christensen
Cubilin is an albumin binding protein important for renal tubular albumin reabsorption.
The Journal of clinical investigation 2000;105(10):1353-61.
2000: Erik I Christensen; Henrik Birn
Renal handling of albumin in normal rat.
Kidney international 2000;57(3):1207-9.
2000: Henrik Birn; Henrik Vorum; Pierre J Verroust; Søren K Moestrup; Erik I Christensen
Receptor-associated protein is important for normal processing of megalin in kidney proximal tubules.
Journal of the American Society of Nephrology : JASN 2000;11(2):191-202.
2000: Pierre J Verroust; Renata Kozyraki; Timothy G Hammond; Søren K Moestrup; Erik I Christensen
Physiopathologic role of cubilin and megalin.
Advances in nephrology from the Necker Hospital 2000;30():127-45.
1999: Jörg R Leheste; B Rolinski; Henrik Vorum; Jan Hilpert; Anders Nykjaer; Christian Jacobsen; P Aucouturier; JO Moskaug; A Otto; Erik I Christensen; Thomas E Willnow
Megalin knockout mice as an animal model of low molecular weight proteinuria.
The American journal of pathology 1999;155(4):1361-70.
1999: Erik I Christensen; Thomas E Willnow
Essential role of megalin in renal proximal tubule for vitamin homeostasis.
Journal of the American Society of Nephrology : JASN 1999;10(10):2224-36.
1999: Renata Kozyraki; John C Fyfe; M Kristiansen; C Gerdes; Christian Jacobsen; S Cui; Erik I Christensen; Maria Aminoff; Albert de La Chapelle; Ralf Krahe; Pierre J Verroust; Søren K Moestrup
The intrinsic factor-vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein.
Nature medicine 1999;5(6):656-61.
1999: Erik I Christensen; JO Moskaug; Henrik Vorum; Christian Jacobsen; Thomas Gundersen; Anders Nykjaer; Rune Blomhoff; Thomas E Willnow; Søren K Moestrup
Evidence for an essential role of megalin in transepithelial transport of retinol.
Journal of the American Society of Nephrology : JASN 1999;10(4):685-95.
1999: Jan Hilpert; Anders Nykjaer; Christian Jacobsen; Gerd Wallukat; R Nielsen; S K Moestrup; Hermann Haller; Friedrich C Luft; Erik I Christensen; Thomas E Willnow
Megalin antagonizes activation of the parathyroid hormone receptor.
The Journal of biological chemistry 1999;274(9):5620-5.
1999: Anders Nykjaer; D Dragun; D Walther; Henrik Vorum; Christian Jacobsen; Joachim Herz; F Melsen; Erik I Christensen; Thomas E Willnow
An endocytic pathway essential for renal uptake and activation of the steroid 25-(OH) vitamin D3.
Cell 1999;96(4):507-15.
1998: Hanna Debiec; Erik I Christensen; Pierre M Ronco
The cell adhesion molecule L1 is developmentally regulated in the renal epithelium and is involved in kidney branching morphogenesis.
The Journal of cell biology 1998;143(7):2067-79.
1998: Rikke Nielsen; Henrik Birn; Søren K Moestrup; M Nielsen; Pierre J Verroust; Erik I Christensen
Characterization of a kidney proximal tubule cell line, LLC-PK1, expressing endocytotic active megalin.
Journal of the American Society of Nephrology : JASN 1998;9(10):1767-76.
1998: Søren K Moestrup; I Schousboe; Christian Jacobsen; Jörg R Leheste; Erik I Christensen; Thomas E Willnow
beta2-glycoprotein-I (apolipoprotein H) and beta2-glycoprotein-I-phospholipid complex harbor a recognition site for the endocytic receptor megalin.
The Journal of clinical investigation 1998;102(5):902-9.
1998: S Cui; L Mata; Arvid B Maunsbach; Erik I Christensen
Ultrastructure of the vacuolar apparatus in the renal proximal tubule microinfused in vivo with the cytological stain light green.
Experimental nephrology 1998;6(4):359-67.
1998: Knut-Jan Andersen; Arvid B Maunsbach; Erik I Christensen
Biochemical and ultrastructural characterization of fluid transporting LLC-PK1 microspheres.
Journal of the American Society of Nephrology : JASN 1998;9(7):1153-68.
1998: Anders Nykjaer; Erik I Christensen; Henrik Vorum; Henrik Hager; Claus M Petersen; H Røigaard; H Y Min; F Vilhardt; L B Møller; S Kornfeld; Jørgen Gliemann
Mannose 6-phosphate/insulin-like growth factor-II receptor targets the urokinase receptor to lysosomes via a novel binding interaction.
The Journal of cell biology 1998;141(3):815-28.
1998: Erik I Christensen; Henrik Birn; Pierre J Verroust; Søren K Moestrup
Megalin-mediated endocytosis in renal proximal tubule.
Renal failure 1998;20(2):191-9.
1998: Søren K Moestrup; Renata Kozyraki; M Kristiansen; JH Kaysen; HH Rasmussen; D Brault; F Pontillon; FO Goda; Erik I Christensen; Timothy G Hammond; Pierre J Verroust
The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins.
The Journal of biological chemistry 1998;273(9):5235-42.
1998: Erik I Christensen; Henrik Birn; Pierre J Verroust; Søren K Moestrup
Membrane receptors for endocytosis in the renal proximal tubule.
International review of cytology 1998;180():237-84.
1997: Henrik Birn; Pierre J Verroust; E Nexo; Henrik Hager; C Jacobsen; Erik I Christensen; S K Moestrup
Characterization of an epithelial approximately 460-kDa protein that facilitates endocytosis of intrinsic factor-vitamin B12 and binds receptor-associated protein.
The Journal of biological chemistry 1997;272(42):26497-504.
1997: S Le Panse; Pierre J Verroust; Erik I Christensen
Internalization and recycling of glycoprotein 280 in BN/MSV yolk sac epithelial cells: a model system of relevance to receptor-mediated endocytosis in the renal proximal tubule.
Experimental nephrology 1997;5(5):375-83.
1997: Anders Nykjaer; M Conese; Erik I Christensen; D Olson; O Cremona; Jørgen Gliemann; F Blasi
Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes.
The EMBO journal 1997;16(10):2610-20.
1997: Bellur Seetharam; Erik I Christensen; S K Moestrup; Timothy G Hammond; Pierre J Verroust
Identification of rat yolk sac target protein of teratogenic antibodies, gp280, as intrinsic factor-cobalamin receptor.
The Journal of clinical investigation 1997;99(10):2317-22.
1997: S Le Panse; E Ayani; Søren Nielsen; P Ronco; Pierre J Verroust; Erik I Christensen
Internalization and recycling of glycoprotein 280 in epithelial cells of yolk sac.
European journal of cell biology 1997;72(3):257-67.
1997: Erik I Christensen; Henrik Birn
Hormone, growth factor, and vitamin handling by proximal tubule cells.
Current opinion in nephrology and hypertension 1997;6(1):20-7.
1997: Henrik Birn; Søren Nielsen; Erik I Christensen
Internalization and apical-to-basolateral transport of folate in rat kidney proximal tubule.
The American journal of physiology 1997;272(1 Pt 2):F70-8.
1996: S Cui; Pierre J Verroust; Søren K Moestrup; Erik I Christensen
Megalin/gp330 mediates uptake of albumin in renal proximal tubule.
The American journal of physiology 1996;271(4 Pt 2):F900-7.
1996: Søren K Moestrup; Henrik Birn; P B Fischer; Claus M Petersen; Pierre J Verroust; Robert B Sim; Erik I Christensen; Ebba Nexø
Megalin-mediated endocytosis of transcobalamin-vitamin-B12 complexes suggests a role of the receptor in vitamin-B12 homeostasis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(16):8612-7.
1995: M Conese; Anders Nykjaer; Claus M Petersen; O Cremona; R Pardi; Peter A Andreasen; Jørgen Gliemann; Erik I Christensen; Francesco Blasi
alpha-2 Macroglobulin receptor/Ldl receptor-related protein(Lrp)-dependent internalization of the urokinase receptor.
The Journal of cell biology 1995;131(6 Pt 1):1609-22.
1995: David Marples; Mark A Knepper; Erik I Christensen; Søren Nielsen
Redistribution of aquaporin-2 water channels induced by vasopressin in rat kidney inner medullary collecting duct.
The American journal of physiology 1995;269(3 Pt 1):C655-64.
1995: Søren K Moestrup; S Cui; Henrik Vorum; C Bregengård; Sara Bjørn; K Norris; Jørgen Gliemann; Erik I Christensen
Evidence that epithelial glycoprotein 330/megalin mediates uptake of polybasic drugs.
The Journal of clinical investigation 1995;96(3):1404-13.
1995: Søren Nielsen; Thomas L Pallone; B L Smith; Erik I Christensen; Peter Agre; Arvid B Maunsbach
Aquaporin-1 water channels in short and long loop descending thin limbs and in descending vasa recta in rat kidney.
The American journal of physiology 1995;268(6 Pt 2):F1023-37.
1995: M L Elkjaer; Henrik Birn; Peter Agre; Erik I Christensen; Søren Nielsen
Effects of microtubule disruption on endocytosis, membrane recycling and polarized distribution of Aquaporin-1 and gp330 in proximal tubule cells.
European journal of cell biology 1995;67(1):57-72.
1995: Erik I Christensen; Søren Nielsen; Søren K Moestrup; C Borre; Arvid B Maunsbach; E de Heer; Pierre Ronco; Timothy G Hammond; Pierre J Verroust
Segmental distribution of the endocytosis receptor gp330 in renal proximal tubules.
European journal of cell biology 1995;66(4):349-64.
1995: David Marples; S Christensen; Erik I Christensen; P D Ottosen; Søren Nielsen
Lithium-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla.
The Journal of clinical investigation 1995;95(4):1838-45.
1995: Søren Nielsen; Chung-Lin Chou; David Marples; Erik I Christensen; BK Kishore; Mark A Knepper
Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(4):1013-7.
1994: S R DiGiovanni; Søren Nielsen; Erik I Christensen; Mark A Knepper
Regulation of collecting duct water channel expression by vasopressin in Brattleboro rat.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):8984-8.
1994: Jørgen Gliemann; Anders Nykjaer; Claus M Petersen; K E Jørgensen; M Nielsen; Peter A Andreasen; Erik I Christensen; Aivar Lookene; Gunilla Olivecrona; Søren K Moestrup
The multiligand alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein (alpha 2MR/LRP). Binding and endocytosis of fluid phase and membrane-associated ligands.
Annals of the New York Academy of Sciences 1994;737():20-38.
1994: Søren K Moestrup; Erik I Christensen; Søren Nielsen; K E Jørgensen; Sara Bjørn; H Røigaard; Jørgen Gliemann
Binding and endocytosis of proteins mediated by epithelial gp330.
Annals of the New York Academy of Sciences 1994;737():124-37.
1993: Søren Nielsen; S R DiGiovanni; Erik I Christensen; Mark A Knepper; H W Harris
Cellular and subcellular immunolocalization of vasopressin-regulated water channel in rat kidney.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(24):11663-7.
1993: S Cui; Søren Nielsen; T Bjerke; Erik I Christensen
Transcellular transport of ferritin in rabbit renal proximal tubules.
Experimental nephrology 1993;1(5):309-18.
1993: Søren K Moestrup; Søren Nielsen; P Andreasen; K E Jørgensen; Anders Nykjaer; H Røigaard; Jørgen Gliemann; Erik I Christensen
Epithelial glycoprotein-330 mediates endocytosis of plasminogen activator-plasminogen activator inhibitor type-1 complexes.
The Journal of biological chemistry 1993;268(22):16564-70.
1993: Søren Nielsen; B L Smith; Erik I Christensen; Peter Agre
Distribution of the aquaporin CHIP in secretory and resorptive epithelia and capillary endothelia.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(15):7275-9.
1993: Henrik Birn; Erik I Christensen
Localization and degradation of calcitonin in renal proximal tubule of rat visualized by immunocytochemistry.
Renal physiology and biochemistry 1993;16(4):167-81.
1993: S Cui; Erik I Christensen
Three-dimensional organization of the vacuolar apparatus involved in endocytosis and membrane recycling of rat kidney proximal tubule cells. An electron-microscopic study of serial sections.
Experimental nephrology 1993;1(3):175-84.
1993: S Cui; Allan Flyvbjerg; Søren Nielsen; Wieland Kiess; Erik I Christensen
IGF-II/Man-6-P receptors in rat kidney: apical localization in proximal tubule cells.
Kidney international 1993;43(4):796-807.
1993: Henrik Birn; J Selhub; Erik I Christensen
Internalization and intracellular transport of folate-binding protein in rat kidney proximal tubule.
The American journal of physiology 1993;264(2 Pt 1):C302-10.
1993: Henrik Birn; Erik I Christensen; Søren Nielsen
Kinetics of endocytosis in renal proximal tubule studied with ruthenium red as membrane marker.
The American journal of physiology 1993;264(2 Pt 2):F239-50.
1993: S Cui; Erik I Christensen; Søren Nielsen
Terminal parts of the membrane recycling process in rat kidney proximal tubule cells.
Contributions to nephrology 1993;101():12-8.
1993: T Bjerke; Søren Nielsen; M I Sheikh; Erik I Christensen
Stepwise degradation of NT in pars convoluta and recta of rabbit proximal tubules: evidence of axial heterogeneity.
The American journal of physiology 1993;264(1 Pt 1):E45-53.
1993: Søren Nielsen; B L Smith; Erik I Christensen; Mark A Knepper; Peter Agre
CHIP28 water channels are localized in constitutively water-permeable segments of the nephron.
The Journal of cell biology 1993;120(2):371-83.
1992: Erik I Christensen; Jørgen Gliemann; Søren K Moestrup
Renal tubule gp330 is a calcium binding receptor for endocytic uptake of protein.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1992;40(10):1481-90.
1991: S Y Cui; Erik I Christensen; Søren Nielsen
Membrane traffic after inhibition of endocytosis in renal proximal tubules.
Journal of structural biology 1991;107(3):201-10.
1991: Erik I Christensen; Søren Nielsen
Structural and functional features of protein handling in the kidney proximal tubule.
Seminars in nephrology 1991;11(4):414-39.
1991: Søren Nielsen; Søren P Sheikh; M I Sheikh; Erik I Christensen
Peptide YY luminal processing and axial heterogeneity of basolateral binding in renal proximal tubules.
The American journal of physiology 1991;260(3 Pt 2):F359-67.
1990: Søren K Moestrup; K Kaltoft; Claus M Petersen; S Pedersen; Jørgen Gliemann; Erik I Christensen
Immunocytochemical identification of the human alpha 2-macroglobulin receptor in monocytes and fibroblasts: monoclonal antibodies define the receptor as a monocyte differentiation antigen.
Experimental cell research 1990;190(2):195-203.
1990: Anders Nykjaer; Claus M Petersen; Erik I Christensen; O Davidsen; Jørgen Gliemann
Urokinase receptors in human monocytes.
Biochimica et biophysica acta 1990;1052(3):399-407.
1990: Henrik Birn; Erik I Christensen
The distribution of calcitonin in rat kidney: an immunocytochemical study.
Contributions to nephrology 1990;83():75-81.
1989: Søren Nielsen; Erik I Christensen
Insulin absorption in renal proximal tubules: a quantitative immunocytochemical study.
Journal of ultrastructure and molecular structure research 1989;102(3):205-20.
1989: T Bjerke; Erik I Christensen; N Boye
Tubular handling of neurotensin in the rat kidney as studied by micropuncture and HPLC.
The American journal of physiology 1989;256(1 Pt 2):F100-6.
1989: Søren Nielsen; Ebba Nexø; Erik I Christensen
Absorption of epidermal growth factor and insulin in rabbit renal proximal tubules.
The American journal of physiology 1989;256(1 Pt 1):E55-63.
1988: A Milton; M Hellfritzsch; Erik I Christensen
Basolateral binding and uptake of 125-I-insulin in proximal tubular cells after peritubular extraction in the avian kidney.
Diabetes research (Edinburgh, Scotland) 1988;7(4):189-95.
1988: T Bjerke; Erik I Christensen; N Boye
Neurotensin metabolism in the kidney: role of tubular fluid.
Contributions to nephrology 1988;68():92-7.
1988: T Bjerke; Søren Nielsen; M Hellfritzsch; Erik I Christensen; Ebba Nexø
Renal tubular handling of epidermal growth factor in rat and rabbit.
Contributions to nephrology 1988;68():98-103.
1988: M Hellfritzsch; Søren Nielsen; Erik I Christensen; J T Nielsen
Basolateral tubular handling of insulin in the kidney.
Contributions to nephrology 1988;68():86-91.
1988: Erik I Christensen; Søren Nielsen; M Hellfritzsch; J T Nielsen
Luminal uptake of insulin in renal proximal tubules.
Contributions to nephrology 1988;68():78-85.
1987: Søren Nielsen; J T Nielsen; Erik I Christensen
Luminal and basolateral uptake of insulin in isolated, perfused, proximal tubules.
The American journal of physiology 1987;253(5 Pt 2):F857-67.
1987: Søren K Moestrup; Erik I Christensen; Lars Sottrup-Jensen; Jørgen Gliemann
Binding and receptor-mediated endocytosis of pregnancy zone protein-proteinase complex in rat macrophages.
Biochimica et biophysica acta 1987;930(3):297-303.
1986: M Hellfritzsch; Erik I Christensen; O Sonne
Luminal uptake and intracellular transport of insulin in renal proximal tubules.
Kidney international 1986;29(5):983-8.
1985: O Davidsen; Erik I Christensen; Jørgen Gliemann
The plasma clearance of human alpha 2-macroglobulin-trypsin complex in the rat is mainly accounted for by uptake into hepatocytes.
Biochimica et biophysica acta 1985;846(1):85-92.