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Alex Chua

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Chemicals & Drugs

Anatomy

Disorders

Physiology

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Rishindra M Reddy; Wen-Shuz Yeow; Alex Chua; Dao M Nguyen; Aris Baras; M Firdos Ziauddin; Susan M Shamimi-Noori; Justin B Maxhimer; David S Schrump; Dao Nguyen
Rapid and profound potentiation of Apo2L/TRAIL-mediated cytotoxicity and apoptosis in thoracic cancer cells by the histone deacetylase inhibitor Trichostatin A: the essential role of the mitochondria-mediated caspase activation cascade.
Wilson S Tsai; Wen-Shuz Yeow; Alex Chua; Rishindra M Reddy; Dao M Nguyen; David S Schrump; Dao Nguyen
Enhancement of Apo2L/TRAIL-mediated cytotoxicity in esophageal cancer cells by cisplatin.
Wen-Shuz Yeow; Aris Baras; Alex Chua; Dao M Nguyen; Shailen S Sehgal; David S Schrump; Dao Nguyen
Gossypol, a phytochemical with BH3-mimetic property, sensitizes cultured thoracic cancer cells to Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand.

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2007: Rishindra M Reddy; Wen-Shuz Yeow; Alex Chua; Dao M Nguyen; Aris Baras; M Firdos Ziauddin; Susan M Shamimi-Noori; Justin B Maxhimer; David S Schrump; Dao Nguyen
Rapid and profound potentiation of Apo2L/TRAIL-mediated cytotoxicity and apoptosis in thoracic cancer cells by the histone deacetylase inhibitor Trichostatin A: the essential role of the mitochondria-mediated caspase activation cascade.
Apoptosis : an international journal on programmed cell death 2007;12(1):55-71.
2006: Wilson S Tsai; Wen-Shuz Yeow; Alex Chua; Rishindra M Reddy; Dao M Nguyen; David S Schrump; Dao Nguyen
Enhancement of Apo2L/TRAIL-mediated cytotoxicity in esophageal cancer cells by cisplatin.
Molecular cancer therapeutics 2006;5(12):2977-90.
2006: Wen-Shuz Yeow; Aris Baras; Alex Chua; Dao M Nguyen; Shailen S Sehgal; David S Schrump; Dao Nguyen
Gossypol, a phytochemical with BH3-mimetic property, sensitizes cultured thoracic cancer cells to Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand.
The Journal of thoracic and cardiovascular surgery 2006;132(6):1356-62.
2006: Dao Nguyen; Wen-Shuz Yeow; M Firdos Ziauddin; Aris Baras; Wilson Tsai; Rishindra M Reddy; Alex Chua; George W Cole; David S Schrump
The essential role of the mitochondria-dependent death-signaling cascade in chemotherapy-induced potentiation of Apo2L/TRAIL cytotoxicity in cultured thoracic cancer cells: amplified caspase 8 is indispensable for combination-mediated massive cell death.
Cancer journal (Sudbury, Mass.) 2006;12(4):257-73.
2006: M Firdos Ziauddin; Wen-Shuz Yeow; Justin B Maxhimer; Aris Baras; Alex Chua; Rishindra M Reddy; Wilson Tsai; George W Cole; David S Schrump; Dao Nguyen
Valproic acid, an antiepileptic drug with histone deacetylase inhibitory activity, potentiates the cytotoxic effect of Apo2L/TRAIL on cultured thoracic cancer cells through mitochondria-dependent caspase activation.
Neoplasia (New York, N.Y.) 2006;8(6):446-57.
2006: Wen-Shuz Yeow; M Firdos Ziauddin; Justin B Maxhimer; S Shamimi-Noori; Aris Baras; Alex Chua; David S Schrump; Dao Nguyen
Potentiation of the anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the kinase inhibitor Staurosporine or its clinically relevant analogue UCN-01.
British journal of cancer 2006;94(10):1436-45.