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Jang-Soo Chun

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Hwanhee Oh; Churl-Hong Chun; Jang-Soo Chun
Dkk-1 expression in chondrocytes inhibits experimental osteoarthritic cartilage destruction in mice.
Hwanhee Oh; Hongryeol Park; Je-Hwang Ryu; Siyoung Yang; Jimin Jeon; Hong-Hee Kim; Hyung Joon Kim; Woo-Shin Kim; Young-Guen Kwon; Churl-Hong Chun; Jang-Soo Chun
Misexpression of Dickkopf-1 in endothelial cells, but not in chondrocytes or hypertrophic chondrocytes, causes defects in endochondral ossification.
Jinseol Rhee; Je-Hwang Ryu; Churl-Hong Chun; Jin-Hong Kim; Jang-Soo Chun
α-Catenin inhibits β-catenin-T-cell factor/lymphoid enhancing factor transcriptional activity and collagen type II expression in articular chondrocytes through formation of Gli3R.α-catenin.β-catenin ternary complex.

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2012: Hwanhee Oh; Churl-Hong Chun; Jang-Soo Chun
Dkk-1 expression in chondrocytes inhibits experimental osteoarthritic cartilage destruction in mice.
Arthritis and rheumatism 2012;64(8):2568-78.
2012: Hwanhee Oh; Hongryeol Park; Je-Hwang Ryu; Siyoung Yang; Jimin Jeon; Hong-Hee Kim; Hyung Joon Kim; Woo-Shin Kim; Young-Guen Kwon; Churl-Hong Chun; Jang-Soo Chun
Misexpression of Dickkopf-1 in endothelial cells, but not in chondrocytes or hypertrophic chondrocytes, causes defects in endochondral ossification.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2012;27(6):1335-44.
2012: Jinseol Rhee; Je-Hwang Ryu; Churl-Hong Chun; Jin-Hong Kim; Jang-Soo Chun
α-Catenin inhibits β-catenin-T-cell factor/lymphoid enhancing factor transcriptional activity and collagen type II expression in articular chondrocytes through formation of Gli3R.α-catenin.β-catenin ternary complex.
The Journal of biological chemistry 2012;287(15):11751-60.
2012: Je-Hwang Ryu; Y Shin; S Yang; Churl-Hong Chun; Yun-Hyun Huh; Jang-Soo Chun
Hypoxia-inducible factor-2α regulates Fas-mediated chondrocyte apoptosis during osteoarthritic cartilage destruction.
Cell death and differentiation 2012;19(3):440-50.
2011: Seon-Myung Kim; Yeon Jung Park; Jin Hee Ryu; Jeomil Bae; In Ha Cho; Kyu Yeong Choi; Jang-Soo Chun; Woo Keun Song
Control of growth cone motility and neurite outgrowth by SPIN90.
Experimental cell research 2011;317(16):2276-87.
2011: Je-Hwang Ryu; Youngnim Shin; Siyoung Yang; Churl-Hong Chun; Jinseol Rhee; Jang-Soo Chun
Interleukin-6 plays an essential role in hypoxia-inducible factor 2α-induced experimental osteoarthritic cartilage destruction in mice.
Arthritis and rheumatism 2011;63(9):2732-43.
2011: Myeong Gu Yeo; Hye Jin Oh; Hong-Suk Cho; Jang-Soo Chun; Eugene E Marcantonio; Woo Keun Song
Phosphorylation of Ser 21 in Fyn regulates its kinase activity, focal adhesion targeting, and is required for cell migration.
Journal of cellular physiology 2011;226(1):236-47.
2010: Siyoung Yang; Jonghwan Kim; Je-Hwang Ryu; Hwanhee Oh; Churl-Hong Chun; Byoung Ju Kim; Byoung-Hyun Min; Jang-Soo Chun
Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction.
Nature medicine 2010;16(6):687-93.
2010: Gil Bu Kang; Hye-Eun Song; Mun-Kyoung Kim; Hyung-Seop Youn; Jung-Gyu Lee; June Yop An; Jang-Soo Chun; Hyesung Jeon; Soo Hyun Eom
Crystal structure of Helicobacter pylori MinE, a cell division topological specificity factor.
Molecular microbiology 2010;76(5):1222-31.
2010: Mihye Kim; Youngnim Shin; Bo-Hee Hong; Yang-Jung Kim; Jang-Soo Chun; Giyoong Tae; Young Ha Kim
In vitro chondrocyte culture in a heparin-based hydrogel for cartilage regeneration.
Tissue engineering. Part C, Methods 2010;16(1):1-10.
2009: Yun-Hyun Huh; Je-Hwang Ryu; Sun Shin; Dong-Uk Lee; Siyoung Yang; Kyung-Shin Oh; Churl-Hong Chun; Jeong-Keun Choi; Woo Keun Song; Jang-Soo Chun
Esophageal cancer related gene 4 (ECRG4) is a marker of articular chondrocyte differentiation and cartilage destruction.
Gene 2009;448(1):7-15.
2009: Ramesh P Thylur; Young-Dae Kim; Min-Sung Kwon; Hyun-Mee Oh; Ho-Keun Kwon; Sang-Hyun Kim; Sin-Hyeog Im; Jang-Soo Chun; Zee-Yong Park; Chang-Duk Jun
Swiprosin-1 is expressed in mast cells and up-regulated through the protein kinase C beta I/eta pathway.
Journal of cellular biochemistry 2009;108(3):705-15.
2009: Young-Dae Kim; Suck-Chei Choi; Tae-Young Oh; Jang-Soo Chun; Chang-Duk Jun
Eupatilin inhibits T-cell activation by modulation of intracellular calcium flux and NF-kappaB and NF-AT activity.
Journal of cellular biochemistry 2009;108(1):225-36.
2009: Carmen Teodorof; Jeom Il Bae; Seon-Myung Kim; Hye Jin Oh; Yong Seok Kang; Jeonghoon Choi; Jang-Soo Chun; Woo Keun Song
SPIN90-IRSp53 complex participates in Rac-induced membrane ruffling.
Experimental cell research 2009;315(14):2410-9.
2009: Ju-Ho Lee; Hyun-Ju Kim; Hae-Deun Kim; Byoung-Cheol Lee; Jang-Soo Chun; Chul-Seung Park
Modulation of the conductance-voltage relationship of the BK(Ca) channel by shortening the cytosolic loop connecting two RCK domains.
Biophysical journal 2009;97(3):730-7.
2008: Hwanhee Oh; Siyoung Yang; Meeyoung Park; Jang-Soo Chun
Matrix metalloproteinase (MMP)-12 regulates MMP-9 expression in interleukin-1beta-treated articular chondrocytes.
Journal of cellular biochemistry 2008;105(6):1443-50.
2008: Jang-Soo Chun; Hwanhee Oh; Siyoung Yang; Meeyoung Park
Wnt signaling in cartilage development and degeneration.
BMB reports 2008;41(7):485-94.
2008: Ho-Keun Kwon; Jae-Seon So; Chung-Goo Lee; Anupama Sahoo; Hwa-Joong Yi; Ji-Na Park; So-yeon Lim; Ki-Chul Hwang; Chang-Duk Jun; Jang-Soo Chun; Sin-Hyeog Im
Foxp3 induces IL-4 gene silencing by affecting nuclear translocation of NFkappaB and chromatin structure.
Molecular immunology 2008;45(11):3205-12.
2007: Eun-Young Choi; Zee-Yong Park; Eun-Ju Choi; Hyun-Mee Oh; SungGa Lee; Suck-Chei Choi; Kang-Min Lee; Sin-Hyeog Im; Jang-Soo Chun; Chang-Duk Jun
Transcriptional regulation of IL-8 by iron chelator in human epithelial cells is independent from NF-kappaB but involves ERK1/2- and p38 kinase-dependent activation of AP-1.
Journal of cellular biochemistry 2007;102(6):1442-57.
2007: Jae-Sung Kim; Zae Young Ryoo; Jang-Soo Chun
Cytokine-like 1 (Cytl1) regulates the chondrogenesis of mesenchymal cells.
The Journal of biological chemistry 2007;282(40):29359-67.
2007: Yun-Hyun Huh; Je-Hwang Ryu; Jang-Soo Chun
Regulation of type II collagen expression by histone deacetylase in articular chondrocytes.
The Journal of biological chemistry 2007;282(23):17123-31.
2007: Sang-Gu Hwang; Sung-Min Song; Jeong-Ran Kim; Chun Shik Park; Woo Keun Song; Jang-Soo Chun
Regulation of type II collagen expression by cyclin-dependent kinase 6, cyclin D1, and p21 in articular chondrocytes.
IUBMB life 2007;59(2):90-8.
2007: Chun Shik Park; Mi Su Lee; Hye-jin Oh; Kyu Yeong Choi; Myeong Gu Yeo; Jang-Soo Chun; Woo Keun Song
Modulation of beta-catenin by cyclin-dependent kinase 6 in Wnt-stimulated cells.
European journal of cell biology 2007;86(2):111-23.
2006: Ah-Ra Ko; Yun-Hyun Huh; Hyun-Chae Lee; Woo Keun Song; Young-Sup Lee; Jang-Soo Chun
Identification and characterization of arginase II as a chondrocyte phenotype-specific gene.
IUBMB life 2006;58(10):597-605.
2006: Je-Hwang Ryu; Jang-Soo Chun
Opposing roles of WNT-5A and WNT-11 in interleukin-1beta regulation of type II collagen expression in articular chondrocytes.
The Journal of biological chemistry 2006;281(31):22039-47.
2006: Eun-Jung Jin; Jae-Han Park; Sun-Young Lee; Jang-Soo Chun; Ok-Sun Bang; Shin-Sung Kang
Wnt-5a is involved in TGF-beta3-stimulated chondrogenic differentiation of chick wing bud mesenchymal cells.
The international journal of biochemistry & cell biology 2006;38(2):183-95.
2005: Sang-Gu Hwang; Sung-Sook Yu; Soo-Woong Lee; Jang-Soo Chun
Wnt-3a regulates chondrocyte differentiation via c-Jun/AP-1 pathway.
FEBS letters 2005;579(21):4837-42.
2005: Sang-Gu Hwang; Sung-Sook Yu; Haryoung Poo; Jang-Soo Chun
c-Jun/activator protein-1 mediates interleukin-1beta-induced dedifferentiation but not cyclooxygenase-2 expression in articular chondrocytes.
The Journal of biological chemistry 2005;280(33):29780-7.
2005: Sang-Gu Hwang; Sung-Sook Yu; Je-Hwang Ryu; Hong Bae Jeon; Yung Joon Yoo; Soo Hyun Eom; Jang-Soo Chun
Regulation of beta-catenin signaling and maintenance of chondrocyte differentiation by ubiquitin-independent proteasomal degradation of alpha-catenin.
The Journal of biological chemistry 2005;280(13):12758-65.
2005: J-S Kim; Zee-Yong Park; Yung Joon Yoo; S-S Yu; Jang-Soo Chun
p38 kinase mediates nitric oxide-induced apoptosis of chondrocytes through the inhibition of protein kinase C zeta by blocking autophosphorylation.
Cell death and differentiation 2005;12(3):201-12.
2004: Young Rae Cho; Sun Joo Lee; Hong Bae Jeon; Zee-Yong Park; Jang-Soo Chun; Yung Joon Yoo
Under-sulfation by PAPS synthetase inhibition modulates the expression of ECM molecules during chondrogenesis.
Biochemical and biophysical research communications 2004;323(3):769-75.
2004: Young-Mee Yoon; Kwan-Hyuck Baek; Sook-Jung Jeong; Hyun-Jin Shin; Geun-Hyoung Ha; Ae-Hwa Jeon; Sang-Gu Hwang; Jang-Soo Chun; Chang-Woo Lee
WD repeat-containing mitotic checkpoint proteins act as transcriptional repressors during interphase.
FEBS letters 2004;575(1-3):23-9.
2004: Hyun-Mee Oh; Suck-Chei Choi; Han-Sol Lee; Churl-Hong Chun; Geom Seog Seo; Eun-Young Choi; Hyun-Ju Lee; Myeung-Su Lee; Joo-Jin Yeom; Suck-Jun Choi; Weon-Cheol Han; Jay Min Oh; Yeun-Tai Chung; Jang-Soo Chun; Kang-Min Lee; Chang-Duk Jun
Combined action of extracellular signal-regulated kinase and p38 kinase rescues Molt4 T cells from nitric oxide-induced apoptotic and necrotic cell death.
Free radical biology & medicine 2004;37(4):463-79.
2004: Sang-Gu Hwang; Je-Hwang Ryu; Il-Chul Kim; Eek-Hoon Jho; Ho-Chul Jung; Kwonseop Kim; Song-Ja Kim; Jang-Soo Chun
Wnt-7a causes loss of differentiated phenotype and inhibits apoptosis of articular chondrocytes via different mechanisms.
The Journal of biological chemistry 2004;279(25):26597-604.
2004: Sun Joo Lee; Hong Bae Jeon; Jeung Hwa Lee; Jong Shin Yoo; Jang-Soo Chun; Yung Joon Yoo
Identification of proteins differentially expressed during chondrogenesis of mesenchymal cells.
FEBS letters 2004;563(1-3):35-40.
2004: Seon-Myung Kim; Min Seong Kwon; Chun Shik Park; Kyeong-Rock Choi; Jang-Soo Chun; Joohong Ahn; Woo Keun Song
Modulation of Thr phosphorylation of integrin beta1 during muscle differentiation.
The Journal of biological chemistry 2004;279(8):7082-90.
2004: Jang-Soo Chun
Expression, activity, and regulation of MAP kinases in cultured chondrocytes.
Methods in molecular medicine 2004;100():291-306.
2003: Chun-Do Oh; Jang-Soo Chun
Signaling mechanisms leading to the regulation of differentiation and apoptosis of articular chondrocytes by insulin-like growth factor-1.
The Journal of biological chemistry 2003;278(38):36563-71.
2003: Sun-Woo Yoon; Sung-Ho Goh; Jang-Soo Chun; Eun-Wie Cho; Myung-Kyu Lee; Kil Lyong Kim; Jae-Jin Kim; Chul-Joong Kim; Haryoung Poo
alpha-Melanocyte-stimulating hormone inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production in leukocytes by modulating protein kinase A, p38 kinase, and nuclear factor kappa B signaling pathways.
The Journal of biological chemistry 2003;278(35):32914-20.
2003: Seo-Hyun Cho; Chun-Do Oh; Song-Ja Kim; Il-Chul Kim; Jang-Soo Chun
Retinoic acid inhibits chondrogenesis of mesenchymal cells by sustaining expression of N-cadherin and its associated proteins.
Journal of cellular biochemistry 2003;89(4):837-47.
2003: Joo-Byoung Yoon; Song-Ja Kim; Sang-Gu Hwang; Sunghoe Chang; Shin-Sung Kang; Jang-Soo Chun
Non-steroidal anti-inflammatory drugs inhibit nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes independent of cyclooxygenase activity.
The Journal of biological chemistry 2003;278(17):15319-25.
2003: Song-Ja Kim; Jang-Soo Chun
Protein kinase C alpha and zeta regulate nitric oxide-induced NF-kappa B activation that mediates cyclooxygenase-2 expression and apoptosis but not dedifferentiation in articular chondrocytes.
Biochemical and biophysical research communications 2003;303(1):206-11.
2003: Seunghyi Kook; Do Hoon Kim; Sang Ryeol Shim; Wook Kim; Jang-Soo Chun; Woo Keun Song
Caspase-dependent cleavage of tensin induces disruption of actin cytoskeleton during apoptosis.
Biochemical and biophysical research communications 2003;303(1):37-45.
2003: Yun-Hyun Huh; Seon-Hee Kim; Song-Ja Kim; Jang-Soo Chun
Differentiation status-dependent regulation of cyclooxygenase-2 expression and prostaglandin E2 production by epidermal growth factor via mitogen-activated protein kinase in articular chondrocytes.
The Journal of biological chemistry 2003;278(11):9691-7.
2003: Dae Joong Kim; Sang Hee Park; Chol Seung Lim; Jang-Soo Chun; Jin-Kyu Kim; Woo Keun Song
Cellular localization of integrin isoforms in phenylephrine-induced hypertrophic cardiac myocytes.
Cell biochemistry and function 2003;21(1):41-8.
2003: Young-Bin Lim; Shin-Sung Kang; Won Gun An; Young-Sup Lee; Jang-Soo Chun; Jong-Kyung Sonn
Chondrogenesis induced by actin cytoskeleton disruption is regulated via protein kinase C-dependent p38 mitogen-activated protein kinase signaling.
Journal of cellular biochemistry 2003;88(4):713-8.
2002: Je-Hwang Ryu; Song-Ja Kim; Seon-Hee Kim; Chun-Do Oh; Sang-Gu Hwang; Churl-Hong Chun; Seung-Hyun Oh; Je Kyung Seong; Tae-Lin Huh; Jang-Soo Chun
Regulation of the chondrocyte phenotype by beta-catenin.
Development (Cambridge, England) 2002;129(23):5541-50.
2002: Jung-Won Ju; Song-Ja Kim; Chang-Duk Jun; Jang-Soo Chun
p38 kinase and c-Jun N-terminal kinase oppositely regulates tumor necrosis factor alpha-induced vascular cell adhesion molecule-1 expression and cell adhesion in chondrosarcoma cells.
IUBMB life 2002;54(5):293-9.
2002: Eun Sun Yang; Christoph Richter; Jang-Soo Chun; Tae-Lin Huh; Shin-Sung Kang; Jeen-Woo Park
Inactivation of NADP(+)-dependent isocitrate dehydrogenase by nitric oxide.
Free radical biology & medicine 2002;33(7):927-37.
2002: Song-Ja Kim; Sang-Gu Hwang; Deug Y Shin; Shin-Sung Kang; Jang-Soo Chun
p38 kinase regulates nitric oxide-induced apoptosis of articular chondrocytes by accumulating p53 via NFkappa B-dependent transcription and stabilization by serine 15 phosphorylation.
The Journal of biological chemistry 2002;277(36):33501-8.
2002: Song-Ja Kim; Han-Gyul Kim; Chun-Do Oh; Sang-Gu Hwang; Woo Keun Song; Yung Joon Yoo; Shin-Sung Kang; Jang-Soo Chun
p38 kinase-dependent and -independent Inhibition of protein kinase C zeta and -alpha regulates nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes.
The Journal of biological chemistry 2002;277(33):30375-81.
2002: Song Ja Kim; Dae Seong Im; Seon Hee Kim; Je-Hwang Ryu; Sang-Gu Hwang; Je Kyung Seong; Churl-Hong Chun; Jang-Soo Chun
Beta-catenin regulates expression of cyclooxygenase-2 in articular chondrocytes.
Biochemical and biophysical research communications 2002;296(1):221-6.
2002: Seung-Hee Jo; So-Hyun Lee; Hang Suk Chun; Su Min Lee; Ho-Jin Koh; Sung-Eun Lee; Jang-Soo Chun; Jeen-Woo Park; Tae-Lin Huh
Cellular defense against UVB-induced phototoxicity by cytosolic NADP(+)-dependent isocitrate dehydrogenase.
Biochemical and biophysical research communications 2002;292(2):542-9.
2002: Chang-Hoon Woo; Hye-Jin You; Sung-Hoon Cho; Young-Woo Eom; Jang-Soo Chun; Yung Joon Yoo; Jae-Hong Kim
Leukotriene B(4) stimulates Rac-ERK cascade to generate reactive oxygen species that mediates chemotaxis.
The Journal of biological chemistry 2002;277(10):8572-8.
2002: Young-Mee Yoon; Song-Ja Kim; Chun-Do Oh; Jung-Won Ju; Woo Keun Song; Yung Joon Yoo; Tae-Lin Huh; Jang-Soo Chun
Maintenance of differentiated phenotype of articular chondrocytes by protein kinase C and extracellular signal-regulated protein kinase.
The Journal of biological chemistry 2002;277(10):8412-20.
2002: Jae-Kyoung Lee; Jae-Chang Jung; Jang-Soo Chun; Shin-Sung Kang; Ok-Sun Bang
Expression of p21WAF1 is dependent on the activation of ERK during vitamin E-succinate-induced monocytic differentiation.
Molecules and cells 2002;13(1):125-9.
2002: Song-Ja Kim; Jung-Won Ju; Chun-Do Oh; Young-Mee Yoon; Woo Keun Song; Jae-Hong Kim; Yung Joon Yoo; Ok-Sun Bang; Shin-Sung Kang; Jang-Soo Chun
ERK-1/2 and p38 kinase oppositely regulate nitric oxide-induced apoptosis of chondrocytes in association with p53, caspase-3, and differentiation status.
The Journal of biological chemistry 2002;277(2):1332-9.
2001: Jae-Woong Chang; Hong Bae Jeon; Jun Hyuck Lee; Jong Shin Yoo; Jang-Soo Chun; Jae-Hong Kim; Yung Joon Yoo
Augmented expression of peroxiredoxin I in lung cancer.
Biochemical and biophysical research communications 2001;289(2):507-12.
2001: Chun-Do Oh; Song-Ja Kim; Jung-Won Ju; Woo Keun Song; J H Kim; Yung Joon Yoo; Jang-Soo Chun
Immunosuppressant rapamycin inhibits protein kinase C alpha and p38 mitogen-activated protein kinase leading to the inhibition of chondrogenesis.
European journal of pharmacology 2001;427(3):175-85.
2001: Young-Woo Eom; Min-Hyuk Yoo; Chang-Hoon Woo; K C Hwang; Woo Keun Song; Yung Joon Yoo; Jang-Soo Chun; Jae-Hong Kim
Implication of the small GTPase Rac1 in the apoptosis induced by UV in Rat-2 fibroblasts.
Biochemical and biophysical research communications 2001;285(3):825-9.
2001: Min-Hyuk Yoo; Chang-Hoon Woo; Hye-Jin You; Sung-Hoon Cho; BC Kim; JE Choi; Jang-Soo Chun; Byung Hak Jhun; Tae Soo Kim; Jae-Hong Kim
Role of the cytosolic phospholipase A2-linked cascade in signaling by an oncogenic, constitutively active Ha-Ras isoform.
The Journal of biological chemistry 2001;276(27):24645-53.
2001: Chol Seung Lim; E S Park; Dae Joong Kim; Y H Song; Soo Hyun Eom; Jang-Soo Chun; Jae-Hong Kim; Jin-Kyu Kim; D Park; Woo Keun Song
SPIN90 (SH3 protein interacting with Nck, 90 kDa), an adaptor protein that is developmentally regulated during cardiac myocyte differentiation.
The Journal of biological chemistry 2001;276(16):12871-8.
2000: Young-Mee Yoon; Chun-Do Oh; Shin-Sung Kang; Jang-Soo Chun
Protein kinase A regulates chondrogenesis of mesenchymal cells at the post-precartilage condensation stage via protein kinase C-alpha signaling.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(11):2197-205.
2000: Chang-Hoon Woo; Young-Woo Eom; Min-Hyuk Yoo; Hye-Jin You; H J Han; Woo Keun Song; Yung Joon Yoo; Jang-Soo Chun; Jae-Hong Kim
Tumor necrosis factor-alpha generates reactive oxygen species via a cytosolic phospholipase A2-linked cascade.
The Journal of biological chemistry 2000;275(41):32357-62.
2000: Y Kang; J S Park; S H Kim; Y J Shin; Wankee Kim; Hee-Jae Joo; Jang-Soo Chun; HJ Kim; MJ Ha
Overexpression of protein kinase C delta represses expression of proliferin in NIH3T3 cells that regulates cell proliferation.
Molecular cell biology research communications : MCBRC 2000;4(3):181-7.
2000: Jae-Hong Kim; J H Kim; Woo Keun Song; J H Kim; Jang-Soo Chun
Sphingosine 1-phosphate activates Erk-1/-2 by transactivating epidermal growth factor receptor in rat-2 cells.
IUBMB life 2000;50(2):119-24.
2000: Young-Bin Lim; Shin-Sung Kang; TK Park; Young-Sup Lee; Jang-Soo Chun; Jong-Kyung Sonn
Disruption of actin cytoskeleton induces chondrogenesis of mesenchymal cells by activating protein kinase C-alpha signaling.
Biochemical and biophysical research communications 2000;273(2):609-13.
2000: Young-Mee Yoon; Chun-Do Oh; D Y Kim; Young-Sup Lee; Jeen-Woo Park; Tae-Lin Huh; Shin-Sung Kang; Jang-Soo Chun
Epidermal growth factor negatively regulates chondrogenesis of mesenchymal cells by modulating the protein kinase C-alpha, Erk-1, and p38 MAPK signaling pathways.
The Journal of biological chemistry 2000;275(16):12353-9.
2000: Chun-Do Oh; SH Chang; Young-Mee Yoon; S J Lee; Young-Sup Lee; Shin-Sung Kang; Jang-Soo Chun
Opposing role of mitogen-activated protein kinase subtypes, erk-1/2 and p38, in the regulation of chondrogenesis of mesenchymes.
The Journal of biological chemistry 2000;275(8):5613-9.
1999: Chun-Do Oh; Shin-Sung Kang; MJ Ha; Jang-Soo Chun
Analysis of protein kinase C isoforms involved in the activation of laminin receptor in Raw264.7 macrophages.
IUBMB life 1999;48(4):439-43.
1999: Chang-Duk Jun; Hyun-Ock Pae; HJ Kwak; JC Yoo; Byung-Min Choi; Chun-Do Oh; Jang-Soo Chun; S G Paik; Y H Park; Hun-Taeg Chung
Modulation of nitric oxide-induced apoptotic death of HL-60 cells by protein kinase C and protein kinase A through mitogen-activated protein kinases and CPP32-like protease pathways.
Cellular immunology 1999;194(1):36-46.
1999: Chang-Duk Jun; Chun-Do Oh; HJ Kwak; Hyun-Ock Pae; JC Yoo; Byung-Min Choi; Jang-Soo Chun; Rae-Kil Park; Hun-Taeg Chung
Overexpression of protein kinase C isoforms protects RAW 264.7 macrophages from nitric oxide-induced apoptosis: involvement of c-Jun N-terminal kinase/stress-activated protein kinase, p38 kinase, and CPP-32 protease pathways.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(6):3395-401.
1999: Ji Yong Kim; MS Yang; Chun-Do Oh; K T Kim; MJ Ha; Shin-Sung Kang; Jang-Soo Chun
Signalling pathway leading to an activation of mitogen-activated protein kinase by stimulating M3 muscarinic receptor.
The Biochemical journal 1999;337 ( Pt 2)():275-80.
1998: Y Y Chang; S J Kim; T K Park; Shin-Sung Kang; MJ Ha; J F Mushinski; Jang-Soo Chun
Modulation of MAP kinase signaling and growth characteristics by the overexpression of protein kinase C in NIH3T3 cells.
Biochemistry and molecular biology international 1998;45(6):1139-48.
1998: SH Chang; Chun-Do Oh; MS Yang; Shin-Sung Kang; Young-Sup Lee; Jong-Kyung Sonn; Jang-Soo Chun
Protein kinase C regulates chondrogenesis of mesenchymes via mitogen-activated protein kinase signaling.
The Journal of biological chemistry 1998;273(30):19213-9.
1998: MS Yang; SH Chang; Jong-Kyung Sonn; Young-Sup Lee; Shin-Sung Kang; TK Park; Jang-Soo Chun
Regulation of chondrogenic differentiation of mesenchymes by protein kinase C alpha.
Molecules and cells 1998;8(3):266-71.
1997: Ji Yong Kim; Young-Sup Lee; Jinseu Park; Jang-Soo Chun
Integrin-mediated activation of mitogen-activated protein kinase is independent of the activation of protein kinase C epsilon during the spreading of HeLa cells on a gelatin substratum.
Molecules and cells 1997;7(5):594-8.
1997: S J Kim; Y Y Chang; Shin-Sung Kang; Jang-Soo Chun
Phorbol ester effects in atypical protein kinase C zeta overexpressing NIH3T3 cells: possible evidence for crosstalk between protein kinase C isoforms.
Biochemical and biophysical research communications 1997;237(2):336-9.
1996: Jang-Soo Chun; MJ Ha; Bruce S Jacobson
Differential translocation of protein kinase C epsilon during HeLa cell adhesion to a gelatin substratum.
The Journal of biological chemistry 1996;271(22):13008-12.
1995: B Choi; Jang-Soo Chun; Young-Sup Lee; Jong-Kyung Sonn; Shin-Sung Kang
Expression of protein kinase C isozymes that are required for chondrogenesis of chick limb bud mesenchymal cells.
Biochemical and biophysical research communications 1995;216(3):1034-40.
1993: Jang-Soo Chun; Bruce S Jacobson
Requirement for diacylglycerol and protein kinase C in HeLa cell-substratum adhesion and their feedback amplification of arachidonic acid production for optimum cell spreading.
Molecular biology of the cell 1993;4(3):271-81.
1992: Jang-Soo Chun; Bruce S Jacobson
Spreading of HeLa cells on a collagen substratum requires a second messenger formed by the lipoxygenase metabolism of arachidonic acid released by collagen receptor clustering.
Molecular biology of the cell 1992;3(5):481-92.