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Fan Chung

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Disorders

Anatomy

Procedures

Living Beings

Physiology

Bronchoconstriction

Phenomena

Forced Expiratory Volume

Chemicals & Drugs

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Publications

TOP 3
Di Stefano A; Caramori G; Gnemmi I; Contoli M; Bristot L; Capelli A; Ricciardolo F L M; Magno F; D'Anna S Ennio; Zanini A; Carbone M; Sabatini F; Usai C; Brun P; Chung K F; Barnes P J; Papi A; Adcock I M; Balbi B
Association of increased CCL5 and CXCL7 chemokine expression with neutrophil activation in severe stable COPD.
Macedo P; Hew M; Torrego A; Jouneau S; Oates T; Durham A; Chung K F
Inflammatory biomarkers in airways of patients with severe asthma compared with non-severe asthma.
Di Stefano A; Caramori G; Gnemmi I; Contoli M; Vicari C; Capelli A; Magno F; D'Anna S E; Zanini A; Brun P; Casolari P; Chung K F; Barnes P J; Papi A; Adcock I; Balbi B
T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients.

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All Publications

2009: Di Stefano A; Caramori G; Gnemmi I; Contoli M; Bristot L; Capelli A; Ricciardolo F L M; Magno F; D'Anna S Ennio; Zanini A; Carbone M; Sabatini F; Usai C; Brun P; Chung K F; Barnes P J; Papi A; Adcock I M; Balbi B
Association of increased CCL5 and CXCL7 chemokine expression with neutrophil activation in severe stable COPD.
Thorax 2009;64(11):968-75.
2009: Macedo P; Hew M; Torrego A; Jouneau S; Oates T; Durham A; Chung K F
Inflammatory biomarkers in airways of patients with severe asthma compared with non-severe asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(11):1668-76.
2009: Di Stefano A; Caramori G; Gnemmi I; Contoli M; Vicari C; Capelli A; Magno F; D'Anna S E; Zanini A; Brun P; Casolari P; Chung K F; Barnes P J; Papi A; Adcock I; Balbi B
T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients.
Clinical and experimental immunology 2009;157(2):316-24.
2009: Mahn Katharina; Hirst Stuart J; Ying Sun; Holt Mark R; Lavender Paul; Ojo Oluwaseun O; Siew Leonard; Simcock David E; McVicker Clare G; Kanabar Varsha; Snetkov Vladimir A; O'Connor Brian J; Karner Charlotta; Cousins David J; Macedo Patricia; Chung K Fan; Corrigan Christopher J; Ward Jeremy P T; Lee Tak H
Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(26):10775-80.
2009: Groneberg-Kloft Beatrix; Scutaru Cristian; Dinh Q Thai; Welte Tobias; Chung K Fan; Fischer Axel; Quarcoo David
Inter-disease comparison of research quantity and quality: bronchial asthma and chronic obstructive pulmonary disease.
The Journal of asthma : official journal of the Association for the Care of Asthma 2009;46(2):147-52.
2009: Groneberg-Kloft B; Dinh Q Thai; Scutaru C; Welte T; Fischer A; Chung K Fan; Quarcoo D
Cough as a symptom and a disease entity: scientometric analysis and density-equalizing calculations.
Journal of investigational allergology & clinical immunology : official organ of the International Association of Asthmology (INTERASMA) and Sociedad Latinoamericana de Alergia e Inmunología 2009;19(4):266-75.
2008: Takemura Masaya; Quarcoo David; Niimi Akio; Dinh Q Thai; Geppetti Pierangelo; Fischer Axel; Chung K Fan; Groneberg David A
Is TRPV1 a useful target in respiratory diseases?
Pulmonary pharmacology & therapeutics 2008;21(6):833-9.
2008: Adcock Ian M; Caramori Gaetano; Chung K Fan
New targets for drug development in asthma.
Lancet 2008;372(9643):1073-87.
2008: Liu W-T; Wang C-H; Lin H-C; Lin S-M; Lee K-Y; Lo Y-L; Hung S-H; Chang Y-M; Chung K F; Kuo H-P
Efficacy of a cell phone-based exercise programme for COPD.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;32(3):651-9.
2008: Bhavsar P; Hew M; Khorasani N; Torrego A; Barnes P J; Adcock I; Chung K F
Relative corticosteroid insensitivity of alveolar macrophages in severe asthma compared with non-severe asthma.
Thorax 2008;63(9):784-90.
2008: Williams A S; Nath P; Leung S-Y; Khorasani N; McKenzie A N J; Adcock I M; Chung K F
Modulation of ozone-induced airway hyperresponsiveness and inflammation by interleukin-13.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;32(3):571-8.
2008: Chung K F; Adcock I M
Multifaceted mechanisms in COPD: inflammation, immunity, and tissue repair and destruction.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;31(6):1334-56.
2007: McCreanor James; Cullinan Paul; Nieuwenhuijsen Mark J; Stewart-Evans James; Malliarou Eleni; Jarup Lars; Harrington Robert; Svartengren Magnus; Han In-Kyu; Ohman-Strickland Pamela; Chung Kian Fan; Zhang Junfeng
Respiratory effects of exposure to diesel traffic in persons with asthma.
The New England journal of medicine 2007;357(23):2348-58.
2007: Pavord Ian D; Cox Gerard; Thomson Neil C; Rubin Adalberto S; Corris Paul A; Niven Robert M; Chung Kian F; Laviolette Michel;
Safety and efficacy of bronchial thermoplasty in symptomatic, severe asthma.
American journal of respiratory and critical care medicine 2007;176(12):1185-91.
2007: Ballantyne Sarah J; Barlow Jillian L; Jolin Helen E; Nath Puneeta; Williams Alison S; Chung Kian Fan; Sturton Graham; Wong See Heng; McKenzie Andrew N J
Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma.
The Journal of allergy and clinical immunology 2007;120(6):1324-31.
2007: Nath Puneeta; Leung Sum Yee; Williams Alison S; Noble Alistair; Xie Shaoping; McKenzie Andrew N J; Chung Kian Fan
Complete inhibition of allergic airway inflammation and remodelling in quadruple IL-4/5/9/13-/- mice.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2007;37(10):1427-35.
2007: Williams Alison S; Leung Sum-Yee; Nath Puneeta; Khorasani Nadia M; Bhavsar Pankaj; Issa Razao; Mitchell Jane A; Adcock Ian M; Chung Kian Fan
Role of TLR2, TLR4, and MyD88 in murine ozone-induced airway hyperresponsiveness and neutrophilia.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;103(4):1189-95.
2007: Lu Dong; Xie Shaoping; Sukkar Maria B; Lu Xinjie; Scully Michael F; Chung Kian Fan
Inhibition of airway smooth muscle adhesion and migration by the disintegrin domain of ADAM-15.
American journal of respiratory cell and molecular biology 2007;37(4):494-500.
2007: Xie Shaoping; Sukkar Maria B; Issa Razao; Khorasani Nadia M; Chung Kian Fan
Mechanisms of induction of airway smooth muscle hyperplasia by transforming growth factor-beta.
American journal of physiology. Lung cellular and molecular physiology 2007;293(1):L245-53.
2007: Williams Alison S; Issa Razao; Leung Sum Yee; Nath Puneeta; Ferguson Gregory D; Bennett Brydon L; Adcock Ian M; Chung Kian Fan
Attenuation of ozone-induced airway inflammation and hyper-responsiveness by c-Jun NH2 terminal kinase inhibitor SP600125.
The Journal of pharmacology and experimental therapeutics 2007;322(1):351-9.
2007: Morice A H; Fontana G A; Belvisi M G; Birring S S; Chung K F; Dicpinigaitis P V; Kastelik J A; McGarvey L P; Smith J A; Tatar M; Widdicombe J;
ERS guidelines on the assessment of cough.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2007;29(6):1256-76.
2007: Issa Razao; Xie Shaoping; Khorasani Nadia; Sukkar Maria; Adcock Ian M; Lee Kang-Yun; Chung Kian Fan
Corticosteroid inhibition of growth-related oncogene protein-alpha via mitogen-activated kinase phosphatase-1 in airway smooth muscle cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(11):7366-75.
2007: McVicker Clare G; Leung Sum-Yee; Kanabar Varsha; Moir Lyn M; Mahn Katharina; Chung K Fan; Hirst Stuart J
Repeated allergen inhalation induces cytoskeletal remodeling in smooth muscle from rat bronchioles.
American journal of respiratory cell and molecular biology 2007;36(6):721-7.
2007: Wenzel Sally E; Balzar Silvana; Ampleford Elizabeth; Hawkins Gregory A; Busse William W; Calhoun William J; Castro Mario; Chung K Fan; Erzurum Serpil; Gaston Benjamin; Israel Elliot; Teague W Gerald; Curran-Everett Douglas; Meyers Deborah A; Bleecker Eugene R
IL4R alpha mutations are associated with asthma exacerbations and mast cell/IgE expression.
American journal of respiratory and critical care medicine 2007;175(6):570-6.
2007: Moore Wendy C; Bleecker Eugene R; Curran-Everett Douglas; Erzurum Serpil C; Ameredes Bill T; Bacharier Leonard; Calhoun William J; Castro Mario; Chung Kian Fan; Clark Melissa P; Dweik Raed A; Fitzpatrick Anne M; Gaston Benjamin; Hew Mark; Hussain Iftikhar; Jarjour Nizar N; Israel Elliot; Levy Bruce D; Murphy James R; Peters Stephen P; Teague W Gerald; Meyers Deborah A; Busse William W; Wenzel Sally E;
Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.
The Journal of allergy and clinical immunology 2007;119(2):405-13.
2007: Leung Sum Yee; Niimi Akio; Williams Alison S; Nath Puneeta; Blanc F-Xavier; Dinh Q Thai; Chung K Fan
Inhibition of citric acid- and capsaicin-induced cough by novel TRPV-1 antagonist, V112220, in guinea-pig.
Cough (London, England) 2007;3():10.
2007: Widdicombe John; Chung Kian Fan
Cough.
Pulmonary pharmacology & therapeutics 2007;20(4):305-6.
2007: Chung K F
Effective antitussives for the cough patient: an unmet need.
Pulmonary pharmacology & therapeutics 2007;20(4):438-45.
2006: Chung K Fan
Intrinsic differences of the airway epithelium in childhood allergic asthma.
American journal of respiratory and critical care medicine 2006;174(10):1066-7.
2006: Lu Dong; Chung Kian Fan; Xia Min; Lu Xinjie; Scully Mike; Kakkar Vijay
Integrin binding characteristics of the disintegrin-like domain of ADAM-15.
Thrombosis and haemostasis 2006;96(5):642-51.
2006: Leung Sum Yee; Niimi Akio; Noble Alistair; Oates Timothy; Williams Alison S; Medicherla Satyanarayana; Protter Andrew A; Chung Kian Fan
Effect of transforming growth factor-beta receptor I kinase inhibitor 2,4-disubstituted pteridine (SD-208) in chronic allergic airway inflammation and remodeling.
The Journal of pharmacology and experimental therapeutics 2006;319(2):586-94.
2006: Lee Kang-Yun; Ho Shu-Chuan; Lin Horng-Chyuan; Lin Shu-Min; Liu Chien-Ying; Huang Chien-Da; Wang Chun-Hua; Chung Kian Fan; Kuo Han-Pin
Neutrophil-derived elastase induces TGF-beta1 secretion in human airway smooth muscle via NF-kappaB pathway.
American journal of respiratory cell and molecular biology 2006;35(4):407-14.
2006: Sukkar Maria B; Xie Shaoping; Khorasani Nadia M; Kon Onn Min; Stanbridge Rex; Issa Razao; Chung Kian Fan
Toll-like receptor 2, 3, and 4 expression and function in human airway smooth muscle.
The Journal of allergy and clinical immunology 2006;118(3):641-8.
2006: Nath Puneeta; Leung Sum-Yee; Williams Alison; Noble Alistair; Chakravarty Sundeep Dugar Sarvajit; Luedtke Gregory R; Medicherla Satyanarayana; Higgins Linda S; Protter Andrew; Chung Kian Fan
Importance of p38 mitogen-activated protein kinase pathway in allergic airway remodelling and bronchial hyperresponsiveness.
European journal of pharmacology 2006;544(1-3):160-7.
2006: Catley Matthew C; Sukkar Maria B; Chung K Fan; Jaffee Bruce; Liao Sha-Mei; Coyle Anthony J; Haddad El-Bdaoui; Barnes Peter J; Newton Robert
Validation of the anti-inflammatory properties of small-molecule IkappaB Kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative IKK1 and IKK2 in human airways smooth muscle.
Molecular pharmacology 2006;70(2):697-705.
2006: Torrego A; Haque R A; Nguyen L T; Hew M; Carr D H; Wilson R; Chung K F
Capsaicin cough sensitivity in bronchiectasis.
Thorax 2006;61(8):706-9.
2006: Issa Razao; Xie Shaoping; Lee Kang-Yun; Stanbridge Rex D; Bhavsar Pankaj; Sukkar Maria B; Chung Kian Fan
GRO-alpha regulation in airway smooth muscle by IL-1beta and TNF-alpha: role of NF-kappaB and MAP kinases.
American journal of physiology. Lung cellular and molecular physiology 2006;291(1):L66-74.
2006: Hew Mark; Bhavsar Pankaj; Torrego Alfons; Meah Sally; Khorasani Nadia; Barnes Peter J; Adcock Ian; Chung Kian Fan
Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma.
American journal of respiratory and critical care medicine 2006;174(2):134-41.
2006: Chung K F
Cytokines as targets in chronic obstructive pulmonary disease.
Current drug targets 2006;7(6):675-81.
2006: Bayram H; Ito K; Issa R; Ito M; Sukkar M; Chung K F
Regulation of human lung epithelial cell numbers by diesel exhaust particles.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2006;27(4):705-13.
2006: Chung Kian Fan; McGarvey Lorcan; Widdicombe John
American College of Chest Physicians' cough guidelines.
Lancet 2006;367(9515):981-2.
2006: Haczku Angela; Cao Yang; Vass Geza; Kierstein Sonja; Nath Puneeta; Atochina-Vasserman Elena N; Scanlon Seth T; Li Lily; Griswold Don E; Chung K Fan; Poulain Francis R; Hawgood Samuel; Beers Michael F; Crouch Erika C
IL-4 and IL-13 form a negative feedback circuit with surfactant protein-D in the allergic airway response.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(6):3557-65.
2006: Adcock Ian M; Chung K Fan; Caramori Gaetano; Ito Kazuhiro
Kinase inhibitors and airway inflammation.
European journal of pharmacology 2006;533(1-3):118-32.
2006: Varani Katia; Caramori Gaetano; Vincenzi Fabrizio; Adcock Ian; Casolari Paolo; Leung Edward; Maclennan Stephen; Gessi Stefania; Morello Silvana; Barnes Peter J; Ito Kazuhiro; Chung Kian Fan; Cavallesco Giorgio; Azzena Gianfranco; Papi Alberto; Borea Pier Andrea
Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2006;173(4):398-406.
2006: Chung K F; Hew M; Score J; Jones A V; Reiter A; Cross N C P; Bain B J
Cough and hypereosinophilia due to FIP1L1-PDGFRA fusion gene with tyrosine kinase activity.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2006;27(1):230-2.
2006: Mann Bhupinder S; Chung Kian Fan
Blood neutrophil activation markers in severe asthma: lack of inhibition by prednisolone therapy.
Respiratory research 2006;7():59.
2005: Chung Kian F
Inflammatory mediators in chronic obstructive pulmonary disease.
Current drug targets. Inflammation and allergy 2005;4(6):619-25.
2005: Ricciardolo Fabio L M; Caramori Gaetano; Ito Kazuhiro; Capelli Armando; Brun Paola; Abatangelo Giovanni; Papi Alberto; Chung Kian Fan; Adcock Ian; Barnes Peter J; Donner Claudio F; Rossi Andrea; Di Stefano Antonino
Nitrosative stress in the bronchial mucosa of severe chronic obstructive pulmonary disease.
The Journal of allergy and clinical immunology 2005;116(5):1028-35.
2005: Torrego Alfonso; Cimbollek Stefan; Hew Mark; Chung Kian Fan
No effect of omeprazole on pH of exhaled breath condensate in cough associated with gastro-oesophageal reflux.
Cough (London, England) 2005;1():10.
2005: Chung K F
Evaluation of selective prostaglandin E2 (PGE2) receptor agonists as therapeutic agents for the treatment of asthma.
Science's STKE : signal transduction knowledge environment 2005;2005(303):pe47.
2005: Niimi Akio; Torrego Alfonso; Nicholson Andrew G; Cosio Borja G; Oates Tim B; Chung Kian Fan
Nature of airway inflammation and remodeling in chronic cough.
The Journal of allergy and clinical immunology 2005;116(3):565-70.
2005: Haque Rubaiyat A; Chung Kian Fan
Cough: meeting the needs of a growing field.
Cough (London, England) 2005;1():1.
2005: Comhair Suzy A A; Ricci Kristin S; Arroliga Mercedes; Lara Abigail R; Dweik Raed A; Song Wei; Hazen Stanley L; Bleecker Eugene R; Busse William W; Chung Kian Fan; Gaston Benjamin; Hastie Annette; Hew Mark; Jarjour Nizar; Moore Wendy; Peters Stephen; Teague W Gerald; Wenzel Sally E; Erzurum Serpil C
Correlation of systemic superoxide dismutase deficiency to airflow obstruction in asthma.
American journal of respiratory and critical care medicine 2005;172(3):306-13.
2005: Leung Sum Yee; Eynott Paul; Nath Puneeta; Chung Kian Fan
Effects of ciclesonide and fluticasone propionate on allergen-induced airway inflammation and remodeling features.
The Journal of allergy and clinical immunology 2005;115(5):989-96.
2005: Oltmanns Ute; Sukkar Maria B; Xie Shaoping; John Matthias; Chung K Fan
Induction of human airway smooth muscle apoptosis by neutrophils and neutrophil elastase.
American journal of respiratory cell and molecular biology 2005;32(4):334-41.
2005: Chung K F
Pathophysiology and therapy of chronic cough.
Minerva medica 2005;96(1):29-40.
2005: Nguyen Lan Tien; Lim Sam; Oates Timothy; Chung Kian Fan
Increase in airway neutrophils after oral but not inhaled corticosteroid therapy in mild asthma.
Respiratory medicine 2005;99(2):200-7.
2005: Chung K Fan; Groneberg David A
Effects of cigarette smoke on pulmonary homeostasis.
American journal of respiratory cell and molecular biology 2005;32(2):167.
2005: Groneberg David A; Peiser Christian; Eynott Paul R; Welker Pia; Erbes Reinhard; Witt Christian; Chung K Fan; Fischer Axel
Transcriptional down-regulation of neurotrophin-3 in chronic obstructive pulmonary disease.
Biological chemistry 2005;386(1):53-9.
2005: Chung K F
Drugs to suppress cough.
Expert opinion on investigational drugs 2005;14(1):19-27.
2005: Nath Puneeta; Eynott Paul; Leung Sum-Yee; Adcock Ian M; Bennett Brydon L; Chung Kian Fan
Potential role of c-Jun NH2-terminal kinase in allergic airway inflammation and remodelling: effects of SP600125.
European journal of pharmacology 2005;506(3):273-83.
2005: Xie Shaoping; Sukkar Maria B; Issa Razao; Oltmanns Ute; Nicholson Andrew G; Chung Kian Fan
Regulation of TGF-beta 1-induced connective tissue growth factor expression in airway smooth muscle cells.
American journal of physiology. Lung cellular and molecular physiology 2005;288(1):L68-76.
2005: Xie Shaoping; Issa Razao; Sukkar Maria B; Oltmanns Ute; Bhavsar Pankaj K; Papi Alberto; Caramori Gaetano; Adcock Ian; Chung K Fan
Induction and regulation of matrix metalloproteinase-12 in human airway smooth muscle cells.
Respiratory research 2005;6():148.
2005: Chung Kian Fan
The role of airway smooth muscle in the pathogenesis of airway wall remodeling in chronic obstructive pulmonary disease.
Proceedings of the American Thoracic Society 2005;2(4):347-54; discussion 371-2.
2005: Oltmanns Ute; Chung Kian F; Walters Matthew; John Matthias; Mitchell Jane A
Cigarette smoke induces IL-8, but inhibits eotaxin and RANTES release from airway smooth muscle.
Respiratory research 2005;6():74.
2005: Wang Chun-Hua; Liu Chien-Ying; Wan Yung-Liang; Chou Chun-Liang; Huang Kuo-Hsiung; Lin Horng-Chyuan; Lin Shu-Min; Lin Tzou-Yien; Chung Kian Fan; Kuo Han-Pin
Persistence of lung inflammation and lung cytokines with high-resolution CT abnormalities during recovery from SARS.
Respiratory research 2005;6():42.
2004: Zhai Wenwu; Eynott Paul R; Oltmanns Ute; Leung Sum Yee; Chung Kian Fan
Mitogen-activated protein kinase signalling pathways in IL-1 beta-dependent rat airway smooth muscle proliferation.
British journal of pharmacology 2004;143(8):1042-9.
2004: Groneberg David A; Niimi Akio; Dinh Q Thai; Cosio Borja; Hew Mark; Fischer Axel; Chung K Fan
Increased expression of transient receptor potential vanilloid-1 in airway nerves of chronic cough.
American journal of respiratory and critical care medicine 2004;170(12):1276-80.
2004: Sukkar Maria B; Issa Razao; Xie Shaoping; Oltmanns Ute; Newton Robert; Chung Kian Fan
Fractalkine/CX3CL1 production by human airway smooth muscle cells: induction by IFN-gamma and TNF-alpha and regulation by TGF-beta and corticosteroids.
American journal of physiology. Lung cellular and molecular physiology 2004;287(6):L1230-40.
2004: Caramori G; Di Gregorio C; Carlstedt I; Casolari P; Guzzinati I; Adcock I M; Barnes P J; Ciaccia A; Cavallesco G; Chung K F; Papi A
Mucin expression in peripheral airways of patients with chronic obstructive pulmonary disease.
Histopathology 2004;45(5):477-84.
2004: Chung K Fan; Caramori Gaetano; Groneberg David A
Airway obstruction in chronic obstructive pulmonary disease.
The New England journal of medicine 2004;351(14):1459-61; author reply 1459-61.
2004: Morice A H; Fontana G A; Sovijarvi A R A; Pistolesi M; Chung K F; Widdicombe J; O'Connell F; Geppetti P; Gronke L; De Jongste J; Belvisi M; Dicpinigaitis P; Fischer A; McGarvey L; Fokkens W J; Kastelik J;
The diagnosis and management of chronic cough.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2004;24(3):481-92.
2004: Djukanovic Ratko; Wilson Susan J; Kraft Monica; Jarjour Nizar N; Steel Mark; Chung K Fan; Bao Weibin; Fowler-Taylor Angel; Matthews John; Busse William W; Holgate Stephen T; Fahy John V
Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma.
American journal of respiratory and critical care medicine 2004;170(6):583-93.
2004: Jarai Gabor; Sukkar Maria; Garrett Sarah; Duroudier Nathalie; Westwick John; Adcock Ian; Chung Kian Fan
Effects of interleukin-1beta, interleukin-13 and transforming growth factor-beta on gene expression in human airway smooth muscle using gene microarrays.
European journal of pharmacology 2004;497(3):255-65.
2004: Di Stefano A; Caramori G; Capelli A; Gnemmi I; Ricciardolo F L; Oates T; Donner C F; Chung K F; Barnes P J; Adcock I M
STAT4 activation in smokers and patients with chronic obstructive pulmonary disease.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2004;24(1):78-85.
2004: Bucchioni E; Csoma Z; Allegra L; Chung K F; Barnes P J; Kharitonov S A
Adenosine 5'-monophosphate increases levels of leukotrienes in breath condensate in asthma.
Respiratory medicine 2004;98(7):651-5.
2004: Niimi A; Nguyen L T; Usmani O; Mann B; Chung K F
Reduced pH and chloride levels in exhaled breath condensate of patients with chronic cough.
Thorax 2004;59(7):608-12.
2004: Eynott Paul R; Xu Li; Bennett Brydon L; Noble Alistair; Leung Sum-Yee; Nath Puneeta; Groneberg David A; Adcock Ian M; Chung K Fan
Effect of an inhibitor of Jun N-terminal protein kinase, SP600125, in single allergen challenge in sensitized rats.
Immunology 2004;112(3):446-53.
2004: Risse Paul-André; Naline Emmanuel; Faisy Christophe; Huchon Gérard; Chung K Fan; Kleinmann Philippe; Advenier Charles; Roche Nicolas
Protease-activated receptor 2 in regulation of bronchomotor tone: effect of tobacco smoking.
Life sciences 2004;75(8):991-1002.
2004: Cosío Borja G; Mann Buphinder; Ito Kazuhiro; Jazrawi Elen; Barnes Peter J; Chung K Fan; Adcock Ian M
Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma.
American journal of respiratory and critical care medicine 2004;170(2):141-7.
2004: Koch A; Giembycz M; Stirling R G; Lim S; Adcock I; Wassermann K; Erdmann E; Chung K F
Effect of smoking on MAP kinase-induced modulation of IL-8 in human alveolar macrophages.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2004;23(6):805-12.
2004: Atzori L; Caramori G; Lim S; Jazrawi E; Donnelly L; Adcock I; Barnes P J; Chung K F
Effect of cigarette smoking on haem-oxygenase expression in alveolar macrophages.
Respiratory medicine 2004;98(6):530-5.
2004: Holgate S T; Bousquet J; Chung K F; Bisgaard H; Pauwels R; Fabbri L; Rabe K; Doherty M; Snell N J C; Cuss F; D'Amato M; Reginster J Y;
Summary of recommendations for the design of clinical trials and the registration of drugs used in the treatment of asthma.
Respiratory medicine 2004;98(6):479-87.
2004: Bumbacea D; Scheerens J; Mann B S; Stirling R G; Chung K F
Failure of sputum eosinophilia after eotaxin inhalation in asthma.
Thorax 2004;59(5):372-5.
2004: Lim S; Caramori G; Tomita K; Jazrawi E; Oates T; Chung K F; Barnes P J; Adcock I M
Differential expression of IL-10 receptor by epithelial cells and alveolar macrophages.
Allergy 2004;59(5):505-14.
2004: Gupta Dheeraj; Keogh Brian; Chung Kian Fan; Ayres Jon G; Harrison David A; Goldfrad Caroline; Brady Anthony R; Rowan Kathy
Characteristics and outcome for admissions to adult, general critical care units with acute severe asthma: a secondary analysis of the ICNARC Case Mix Programme Database.
Critical care (London, England) 2004;8(2):R112-21.
2004: Groneberg David A; Fischer Axel; Chung K Fan; Daniel Hannelore
Molecular mechanisms of pulmonary peptidomimetic drug and peptide transport.
American journal of respiratory cell and molecular biology 2004;30(3):251-60.
2004: Koch Andrea; Giembycz Mark; Ito Kazuhiro; Lim Sam; Jazrawi Elen; Barnes Peter J; Adcock Ian; Erdmann Erland; Chung K Fan
Mitogen-activated protein kinase modulation of nuclear factor-kappaB-induced granulocyte macrophage-colony-stimulating factor release from human alveolar macrophages.
American journal of respiratory cell and molecular biology 2004;30(3):342-9.
2004: Chung K Fan
Anti-IgE monoclonal antibody, omalizumab: a new treatment for allergic asthma.
Expert opinion on pharmacotherapy 2004;5(2):439-46.
2004: Leung S-Y; Eynott P; Noble A; Nath P; Chung K F
Resolution of allergic airways inflammation but persistence of airway smooth muscle proliferation after repeated allergen exposures.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(2):213-20.
2004: Groneberg David A; Wagner Ulrich; Chung K Fan
Mucus and fatal asthma.
The American journal of medicine 2004;116(1):66-7; author reply 67.
2004: Chung K Fan; Adcock Ian M
Combination therapy of long-acting beta2-adrenoceptor agonists and corticosteroids for asthma.
Treatments in respiratory medicine 2004;3(5):279-89.
2004: Chung Kian Fan; Widdicombe John
Acute and chronic cough.
Pulmonary pharmacology & therapeutics 2004;17(6):471-3.
2004: Niimi Akio; Chung K Fan
Airway inflammation and remodelling changes in patients with chronic cough: do they tell us about the cause of cough?
Pulmonary pharmacology & therapeutics 2004;17(6):441-6.
2004: Groneberg David A; Chung K Fan
Models of chronic obstructive pulmonary disease.
Respiratory research 2004;5():18.
2004: Groneberg David A; Folkerts Gert; Peiser Christian; Chung K Fan; Fischer Axel
Neuropeptide Y (NPY).
Pulmonary pharmacology & therapeutics 2004;17(4):173-80.
2004: John Matthias; Oltmanns Ute; Binder Claudia; Meiners Silke; Gellert Klaus; Chung K Fan; Witt Christian
Inhibition of chemokine production from human airway smooth muscle cells by fluticasone, budesonide and beclomethasone.
Pulmonary pharmacology & therapeutics 2004;17(1):41-7.
2003: Eynott Paul R; Nath Puneeta; Leung Sum-Yee; Adcock Ian M; Bennett Brydon L; Chung K Fan
Allergen-induced inflammation and airway epithelial and smooth muscle cell proliferation: role of Jun N-terminal kinase.
British journal of pharmacology 2003;140(8):1373-80.
2003: Chung Kian Fan
Individual cytokines contributing to asthma pathophysiology: valid targets for asthma therapy?
Current opinion in investigational drugs (London, England : 2000) 2003;4(11):1320-6.
2003: Robinson D S; Campbell D A; Durham S R; Pfeffer J; Barnes P J; Chung K F;
Systematic assessment of difficult-to-treat asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2003;22(3):478-83.
2003: Chung K Fan
Current and future prospects for drugs to suppress cough.
IDrugs : the investigational drugs journal 2003;6(8):781-6.
2003: Oltmanns Ute; Issa Razao; Sukkar Maria B; John Matthias; Chung K Fan
Role of c-jun N-terminal kinase in the induced release of GM-CSF, RANTES and IL-8 from human airway smooth muscle cells.
British journal of pharmacology 2003;139(6):1228-34.
2003: Eynott Paul R; Salmon Michael; Huang Tung-Jung; Oates Timothy; Nicklin Paul L; Chung K Fan
Effects of cyclosporin A and a rapamycin derivative (SAR943) on chronic allergic inflammation in sensitized rats.
Immunology 2003;109(3):461-7.
2003: Groneberg D A; Witt C; Wagner U; Chung K F; Fischer A
Fundamentals of pulmonary drug delivery.
Respiratory medicine 2003;97(4):382-7.
2003: Caramori G; Romagnoli M; Casolari P; Bellettato C; Casoni G; Boschetto P; Chung K F; Barnes P J; Adcock I M; Ciaccia A; Fabbri L M; Papi A
Nuclear localisation of p65 in sputum macrophages but not in sputum neutrophils during COPD exacerbations.
Thorax 2003;58(4):348-51.
2003: Wang Chun-Hua; Lin Horng-Chyuan; Lin Chien-Huang; Yu Chih-Teng; Liu Su-Ling; Huang Kuo-Hsiung; Chung Kian Fan; Kuo Han-Pin
Effect of theophylline and specific phosphodiesterase IV inhibition on proliferation and apoptosis of progenitor cells in bronchial asthma.
British journal of pharmacology 2003;138(6):1147-55.
2003: Roche N; Stirling R G; Lim S; Oliver B G; Chung K F
Regulation of protease-activated receptor-1 in mononuclear cells by neutrophil proteases.
Respiratory medicine 2003;97(3):228-33.
2003: Groneberg David A; Peiser Christian; Dinh Q Thai; Matthias John; Eynott Paul R; Heppt Werner; Carlstedt Ingemar; Witt Christian; Fischer Axel; Chung K Fan
Distribution of respiratory mucin proteins in human nasal mucosa.
The Laryngoscope 2003;113(3):520-4.
2003: Roche Nicolas; Stirling Robert G; Lim Sam; Oliver Brian G; Oates Tim; Jazrawi Elen; Caramori Gaetano; Chung K Fan
Effect of acute and chronic inflammatory stimuli on expression of protease-activated receptors 1 and 2 in alveolar macrophages.
The Journal of allergy and clinical immunology 2003;111(2):367-73.
2003: Eynott Paul R; Paavolainen Niko; Groneberg David A; Noble Alistair; Salmon Michael; Nath Puneeta; Leung Sum-Yee; Chung K Fan
Role of nitric oxide in chronic allergen-induced airway cell proliferation and inflammation.
The Journal of pharmacology and experimental therapeutics 2003;304(1):22-9.
2003: Moir Lyn M; Leung Sum-Yee; Eynott Paul R; McVicker Clare G; Ward Jeremy P T; Chung K Fan; Hirst Stuart J
Repeated allergen inhalation induces phenotypic modulation of smooth muscle in bronchioles of sensitized rats.
American journal of physiology. Lung cellular and molecular physiology 2003;284(1):L148-59.
2002: Mattos Waldo; Lim Sam; Russell Richard; Jatakanon Anon; Chung K Fan; Barnes Peter J
Matrix metalloproteinase-9 expression in asthma: effect of asthma severity, allergen challenge, and inhaled corticosteroids.
Chest 2002;122(5):1543-52.
2002: Di Stefano A; Caramori G; Oates T; Capelli A; Lusuardi M; Gnemmi I; Ioli F; Chung K F; Donner C F; Barnes P J; Adcock I M
Increased expression of nuclear factor-kappaB in bronchial biopsies from smokers and patients with COPD.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2002;20(3):556-63.
2002: Eynott Paul R; Groneberg David A; Caramori Gaetano; Adcock Ian M; Donnelly Louise E; Kharitonov Sergei; Barnes Peter J; Chung K Fan
Role of nitric oxide in allergic inflammation and bronchial hyperresponsiveness.
European journal of pharmacology 2002;452(1):123-33.
2002: Tomita Katsuyuki; Caramori Gaetano; Lim Sam; Ito Kazuhiro; Hanazawa Toyoyuki; Oates Timothy; Chiselita Irena; Jazrawi Elen; Chung K Fan; Barnes Peter J; Adcock Ian M
Increased p21(CIP1/WAF1) and B cell lymphoma leukemia-x(L) expression and reduced apoptosis in alveolar macrophages from smokers.
American journal of respiratory and critical care medicine 2002;166(5):724-31.
2002: Chung K Fan
Anti-IgE therapy of asthma.
Current opinion in investigational drugs (London, England : 2000) 2002;3(8):1157-60.
2002: Chung K Fan; van Rennen Elizabeth L J; Stirling Robert G; Barnes Peter J
Duplicate publication.
American journal of respiratory and critical care medicine 2002;166(4):625.
2002: Ito Kazuhiro; Caramori Gaetano; Lim Sam; Oates Tim; Chung K Fan; Barnes Peter J; Adcock Ian M
Expression and activity of histone deacetylases in human asthmatic airways.
American journal of respiratory and critical care medicine 2002;166(3):392-6.
2002: Chung K F
Cough: potential pharmacological developments.
Expert opinion on investigational drugs 2002;11(7):955-63.
2002: Ito Kazuhiro; Lim Sam; Caramori Gaetano; Cosio Borja; Chung K Fan; Adcock Ian M; Barnes Peter J
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(13):8921-6.
2002: Newton Robert; Eddleston Jane; Haddad El-Bdaoui; Hawisa Samia; Mak Judith; Lim Sam; Fox Alison J; Donnelly Louise E; Chung K Fan
Regulation of kinin receptors in airway epithelial cells by inflammatory cytokines and dexamethasone.
European journal of pharmacology 2002;441(3):193-202.
2002: Groneberg D A; Eynott P R; Lim S; Oates T; Wu R; Carlstedt I; Roberts P; McCann B; Nicholson A G; Harrison B D; Chung K F
Expression of respiratory mucins in fatal status asthmaticus and mild asthma.
Histopathology 2002;40(4):367-73.
2002: Irusen Elvis; Matthews John G; Takahashi Atsushi; Barnes Peter J; Chung Kian F; Adcock Ian M
p38 Mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma.
The Journal of allergy and clinical immunology 2002;109(4):649-57.
2002: Tomita Katsuyuki; Lim Sam; Hanazawa Toyoyuki; Usmani Omar; Stirling Rob; Chung K Fan; Barnes Peter J; Adcock Ian M
Attenuated production of intracellular IL-10 and IL-12 in monocytes from patients with severe asthma.
Clinical immunology (Orlando, Fla.) 2002;102(3):258-66.
2002: Huang Tung Jung; Eynott Paul; Salmon Michael; Nicklin Paul L; Chung K Fan
Effect of topical immunomodulators on acute allergic inflammation and bronchial hyperresponsiveness in sensitised rats.
European journal of pharmacology 2002;437(3):187-94.
2002: Mak Judith C W; Hisada Takeshi; Salmon Michael; Barnes Peter J; Chung K Fan
Glucocorticoids reverse IL-1beta-induced impairment of beta-adrenoceptor-mediated relaxation and up-regulation of G-protein-coupled receptor kinases.
British journal of pharmacology 2002;135(4):987-96.
2002: Groneberg D A; Eynott P R; Oates T; Lim S; Wu R; Carlstedt I; Nicholson A G; Chung K F
Expression of MUC5AC and MUC5B mucins in normal and cystic fibrosis lung.
Respiratory medicine 2002;96(2):81-6.
2002: Adcock Ian M; Chung K Fan
Overview: why are corticosteroids ineffective in COPD?
Current opinion in investigational drugs (London, England : 2000) 2002;3(1):58-60.
2002: Groneberg D A; Eynott P R; Döring F; Dinh Q Thai; Oates T; Barnes P J; Chung K F; Daniel H; Fischer A
Distribution and function of the peptide transporter PEPT2 in normal and cystic fibrosis human lung.
Thorax 2002;57(1):55-60.
2002: Chung K F; Chang A B
Therapy for cough: active agents.
Pulmonary pharmacology & therapeutics 2002;15(3):335-8.
2002: Chung K F
Assessment and measurement of cough: the value of new tools.
Pulmonary pharmacology & therapeutics 2002;15(3):267-72.
2001: Lazzeri N; Belvisi M G; Patel H J; Chung K F; Yacoub M H; Mitchell J A
RANTES release by human airway smooth muscle: effects of prostaglandin E(2) and fenoterol.
European journal of pharmacology 2001;433(2-3):231-5.
2001: Kuo H P; Wang C H; Lin H C; Hwang K S; Liu S L; Chung K F
Interleukin-5 in growth and differentiation of blood eosinophil progenitors in asthma: effect of glucocorticoids.
British journal of pharmacology 2001;134(7):1539-47.
2001: van Rensen E L; Stirling R G; Scheerens J; Staples K; Sterk P J; Barnes P J; Chung K F
Evidence for systemic rather than pulmonary effects of interleukin-5 administration in asthma.
Thorax 2001;56(12):935-40.
2001: Huang T J; Adcock I M; Chung K F
A novel transcription factor inhibitor, SP100030, inhibits cytokine gene expression, but not airway eosinophilia or hyperresponsiveness in sensitized and allergen-exposed rat.
British journal of pharmacology 2001;134(5):1029-36.
2001: Stirling R G; van Rensen E L; Barnes P J; Chung K F
Interleukin-5 induces CD34(+) eosinophil progenitor mobilization and eosinophil CCR3 expression in asthma.
American journal of respiratory and critical care medicine 2001;164(8 Pt 1):1403-9.
2001: Caramori G; Lim S; Ito K; Tomita K; Oates T; Jazrawi E; Chung K F; Barnes P J; Adcock I M
Expression of GATA family of transcription factors in T-cells, monocytes and bronchial biopsies.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;18(3):466-73.
2001: Stirling R G; Chung K F
Severe asthma: definition and mechanisms.
Allergy 2001;56(9):825-40.
2001: Lim S; Tomita K; Caramori G; Jatakanon A; Oliver B; Keller A; Adcock I; Chung K F; Barnes P J;
Low-dose theophylline reduces eosinophilic inflammation but not exhaled nitric oxide in mild asthma.
American journal of respiratory and critical care medicine 2001;164(2):273-6.
2001: Di Stefano A; Capelli A; Lusuardi M; Caramori G; Balbo P; Ioli F; Sacco S; Gnemmi I; Brun P; Adcock I M; Balbi B; Barnes P J; Chung K F; Donner C F
Decreased T lymphocyte infiltration in bronchial biopsies of subjects with severe chronic obstructive pulmonary disease.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2001;31(6):893-902.
2001: Ito K; Lim S; Caramori G; Chung K F; Barnes P J; Adcock I M
Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(6):1110-2.
2001: Lazzeri N; Belvisi M G; Patel H J; Yacoub M H; Chung K F; Mitchell J A
Effects of prostaglandin E2 and cAMP elevating drugs on GM-CSF release by cultured human airway smooth muscle cells. Relevance to asthma therapy.
American journal of respiratory cell and molecular biology 2001;24(1):44-48.
2001: Huang T J; MacAry P A; Eynott P; Moussavi A; Daniel K C; Askenase P W; Kemeny D M; Chung K F
Allergen-specific Th1 cells counteract efferent Th2 cell-dependent bronchial hyperresponsiveness and eosinophilic inflammation partly via IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):207-17.
2000: Stirling R G; Chung K F
New immunological approaches and cytokine targets in asthma and allergy.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2000;16(6):1158-74.
2000: Leckie M J; ten Brinke A; Khan J; Diamant Z; O'Connor B J; Walls C M; Mathur A K; Cowley H C; Chung K F; Djukanovic R; Hansel T T; Holgate S T; Sterk P J; Barnes P J
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.
Lancet 2000;356(9248):2144-8.
2000: Lim S; Groneberg D; Fischer A; Oates T; Caramori G; Mattos W; Adcock I; Barnes P J; Chung K F
Expression of heme oxygenase isoenzymes 1 and 2 in normal and asthmatic airways: effect of inhaled corticosteroids.
American journal of respiratory and critical care medicine 2000;162(5):1912-8.
2000: Salmon M; Liu Y C; Mak J C; Rousell J; Huang T J; Hisada T; Nicklin P L; Chung K F
Contribution of upregulated airway endothelin-1 expression to airway smooth muscle and epithelial cell DNA synthesis after repeated allergen exposure of sensitized Brown-Norway rats.
American journal of respiratory cell and molecular biology 2000;23(5):618-25.
2000: Lim S; Roche N; Oliver B G; Mattos W; Barnes P J; Chung K F
Balance of matrix metalloprotease-9 and tissue inhibitor of metalloprotease-1 from alveolar macrophages in cigarette smokers. Regulation by interleukin-10.
American journal of respiratory and critical care medicine 2000;162(4 Pt 1):1355-60.
2000: Lim S; Jatakanon A; Gordon D; Macdonald C; Chung K F; Barnes P J
Comparison of high dose inhaled steroids, low dose inhaled steroids plus low dose theophylline, and low dose inhaled steroids alone in chronic asthma in general practice.
Thorax 2000;55(10):837-41.
2000: Chung K F; Naya I
Compliance with an oral asthma medication: a pilot study using an electronic monitoring device.
Respiratory medicine 2000;94(9):852-8.
2000: Nightingale J A; Maggs R; Cullinan P; Donnelly L E; Rogers D F; Kinnersley R; Chung K F; Barnes P J; Ashmore M; Newman-Taylor A
Airway inflammation after controlled exposure to diesel exhaust particulates.
American journal of respiratory and critical care medicine 2000;162(1):161-6.
2000: Hisada T; Salmon M; Nasuhara Y; Chung K F
Involvement of haemoxygenase-1 in ozone-induced airway inflammation and hyperresponsiveness.
European journal of pharmacology 2000;399(2-3):229-34.
2000: Haddad E B; Fox A J; Rousell J; Burgess G; McIntyre P; Barnes P J; Chung K F
Post-transcriptional regulation of bradykinin B1 and B2 receptor gene expression in human lung fibroblasts by tumor necrosis factor-alpha: modulation by dexamethasone.
Molecular pharmacology 2000;57(6):1123-31.
2000: Chung K F
Airway smooth muscle cells: contributing to and regulating airway mucosal inflammation?
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2000;15(5):961-8.
2000: Lim S; John M; Seybold J; Taylor D; Witt C; Barnes P J; Chung K F
Increased interleukin-10 and macrophage inflammatory protein-1 alpha release from blood monocytes ex vivo during late-phase response to allergen in asthma.
Allergy 2000;55(5):489-95.
2000: Lim S; Jatakanon A; Meah S; Oates T; Chung K F; Barnes P J
Relationship between exhaled nitric oxide and mucosal eosinophilic inflammation in mild to moderately severe asthma.
Thorax 2000;55(3):184-8.
2000: Nightingale J A; Rogers D F; Chung K F; Barnes P J
No effect of inhaled budesonide on the response to inhaled ozone in normal subjects.
American journal of respiratory and critical care medicine 2000;161(2 Pt 1):479-86.
2000: Hart L; Lim S; Adcock I; Barnes P J; Chung K F
Effects of inhaled corticosteroid therapy on expression and DNA-binding activity of nuclear factor kappaB in asthma.
American journal of respiratory and critical care medicine 2000;161(1):224-31.
2000: Chung K F; Adcock I M
Induction of nuclear factor-kappa B by exposure to ozone and inhibition by glucocorticoids.
Methods in enzymology 2000;319():551-62.
1999: Kharitonov S A; Sapienza M M; Chung K F; Barnes P J
Prostaglandins mediate bradykinin-induced reduction of exhaled nitric oxide in asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(5):1023-7.
1999: Huang T J; Haddad E B; Fox A J; Salmon M; Jones C; Burgess G; Chung K F
Contribution of bradykinin B(1) and B(2) receptors in allergen-induced bronchial hyperresponsiveness.
American journal of respiratory and critical care medicine 1999;160(5 Pt 1):1717-23.
1999: Jatakanon A; Uasuf C; Maziak W; Lim S; Chung K F; Barnes P J
Neutrophilic inflammation in severe persistent asthma.
American journal of respiratory and critical care medicine 1999;160(5 Pt 1):1532-9.
1999: Huang T J; MacAry P A; Wilke T; Kemeny D M; Chung K F
Inhibitory effects of endogenous and exogenous interferon-gamma on bronchial hyperresponsiveness, allergic inflammation and T-helper 2 cytokines in Brown-Norway rats.
Immunology 1999;98(2):280-8.
1999: Wang C H; Hsieh W Y; Shih L Y; Lin H C; Liu C Y; Chung K F; Kuo H P
Increased progenitor cell proliferation in the peripheral blood of patients with bronchial asthma: the role of nitric oxide.
The Journal of allergy and clinical immunology 1999;104(4 Pt 1):803-10.
1999: Patel H J; Belvisi M G; Donnelly L E; Yacoub M H; Chung K F; Mitchell J A
Constitutive expressions of type I NOS in human airway smooth muscle cells: evidence for an antiproliferative role.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(13):1810-6.
1999: Salmon M; Walsh D A; Koto H; Barnes P J; Chung K F
Repeated allergen exposure of sensitized Brown-Norway rats induces airway cell DNA synthesis and remodelling.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(3):633-41.
1999: Huang T J; Newton R; Haddad E B; Chung K F
Differential regulation of cytokine expression after allergen exposure of sensitized rats by cyclosporin A and corticosteroids: relationship to bronchial hyperresponsiveness.
The Journal of allergy and clinical immunology 1999;104(3 Pt 1):644-52.
1999: Chung K F; Barnes P J
Cytokines in asthma.
Thorax 1999;54(9):825-57.
1999: Hisada T; Salmon M; Nasuhara Y; Chung K F
Cysteinyl-leukotrienes partly mediate eotaxin-induced bronchial hyperresponsiveness and eosinophilia in IL-5 transgenic mice.
American journal of respiratory and critical care medicine 1999;160(2):571-5.
1999: Salmon M; Walsh D A; Huang T J; Barnes P J; Leonard T B; Hay D W; Chung K F
Involvement of cysteinyl leukotrienes in airway smooth muscle cell DNA synthesis after repeated allergen exposure in sensitized Brown Norway rats.
British journal of pharmacology 1999;127(5):1151-8.
1999: Chung K F; Patel H J; Fadlon E J; Rousell J; Haddad E B; Jose P J; Mitchell J; Belvisi M
Induction of eotaxin expression and release from human airway smooth muscle cells by IL-1beta and TNFalpha: effects of IL-10 and corticosteroids.
British journal of pharmacology 1999;127(5):1145-50.
1999: Hisada T; Adcock I M; Nasuhara Y; Salmon M; Huang T J; Barnes P J; Chung K F
Inhibition of ozone-induced lung neutrophilia and nuclear factor-kappaB binding activity by vitamin A in rat.
European journal of pharmacology 1999;377(1):63-8.
1999: John M; Hirst S J; Chung K F; Witt C
[Airway myocytes as immune effector cells in the pathogenesis of bronchial asthma. Myocyte culture as an in vitro model]
Pneumologie (Stuttgart, Germany) 1999;53(6):302-6.
1999: Chung K F; Godard P; Adelroth E; Ayres J; Barnes N; Barnes P; Bel E; Burney P; Chanez P; Connett G; Corrigan C; de Blic J; Fabbri L; Holgate S T; Ind P; Joos G; Kerstjens H; Leuenberger P; Lofdahl C G; McKenzie S; Magnussen H; Postma D; Saetta M; Salmeron S; Sterk P
Difficult/therapy-resistant asthma: the need for an integrated approach to define clinical phenotypes, evaluate risk factors, understand pathophysiology and find novel therapies. ERS Task Force on Difficult/Therapy-Resistant Asthma. European Respiratory Society.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;13(5):1198-208.
1999: Hisada T; Hellewell P G; Teixeira M M; Malm M G; Salmon M; Huang T J; Chung K F
alpha4 integrin-dependent eotaxin induction of bronchial hyperresponsiveness and eosinophil migration in interleukin-5 transgenic mice.
American journal of respiratory cell and molecular biology 1999;20(5):992-1000.
1999: Jatakanon A; Lalloo U G; Lim S; Chung K F; Barnes P J
Increased neutrophils and cytokines, TNF-alpha and IL-8, in induced sputum of non-asthmatic patients with chronic dry cough.
Thorax 1999;54(3):234-7.
1999: Huang T J; MacAry P A; Kemeny D M; Chung K F
Effect of CD8+ T-cell depletion on bronchial hyper-responsiveness and inflammation in sensitized and allergen-exposed Brown-Norway rats.
Immunology 1999;96(3):416-23.
1999: Lim S; Jatakanon A; John M; Gilbey T; O'connor B J; Chung K F; Barnes P J
Effect of inhaled budesonide on lung function and airway inflammation. Assessment by various inflammatory markers in mild asthma.
American journal of respiratory and critical care medicine 1999;159(1):22-30.
1998: Stirling R G; Kharitonov S A; Campbell D; Robinson D S; Durham S R; Chung K F; Barnes P J
Increase in exhaled nitric oxide levels in patients with difficult asthma and correlation with symptoms and disease severity despite treatment with oral and inhaled corticosteroids. Asthma and Allergy Group.
Thorax 1998;53(12):1030-4.
1998: Chung K F
Corticosteroid responsiveness and the evolution of asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1998;28 Suppl 5():126-32; discussion 171-3.
1998: Jatakanon A; Lim S; Chung K F; Barnes P J
An inhaled steroid improves markers of airway inflammation in patients with mild asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;12(5):1084-8.
1998: Hart L A; Krishnan V L; Adcock I M; Barnes P J; Chung K F
Activation and localization of transcription factor, nuclear factor-kappaB, in asthma.
American journal of respiratory and critical care medicine 1998;158(5 Pt 1):1585-92.
1998: Kharitonov S A; Sapienza M A; Barnes P J; Chung K F
Prostaglandins E2 and F2alpha reduce exhaled nitric oxide in normal and asthmatic subjects irrespective of airway caliber changes.
American journal of respiratory and critical care medicine 1998;158(5 Pt 1):1374-8.
1998: Horváth I; Donnelly L E; Kiss A; Kharitonov S A; Lim S; Chung K F; Barnes P J
Combined use of exhaled hydrogen peroxide and nitric oxide in monitoring asthma.
American journal of respiratory and critical care medicine 1998;158(4):1042-6.
1998: Nightingale J A; Rogers D F; Hart L A; Kharitonov S A; Chung K F; Barnes P J
Effect of inhaled endotoxin on induced sputum in normal, atopic, and atopic asthmatic subjects.
Thorax 1998;53(7):563-71.
1998: Sapienza M A; Kharitonov S A; Horvath I; Chung K F; Barnes P J
Effect of inhaled L-arginine on exhaled nitric oxide in normal and asthmatic subjects.
Thorax 1998;53(3):172-5.
1998: Lalloo U G; Lim S; DuBois R; Barnes P J; Chung K F
Increased sensitivity of the cough reflex in progressive systemic sclerosis patients with interstitial lung disease.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;11(3):702-5.
1998: Salmon M; Koto H; Lynch O T; Haddad E B; Lamb N J; Quinlan G J; Barnes P J; Chung K F
Proliferation of airway epithelium after ozone exposure: effect of apocynin and dexamethasone.
American journal of respiratory and critical care medicine 1998;157(3 Pt 1):970-7.
1998: Jatakanon A; Lim S; Kharitonov S A; Chung K F; Barnes P J
Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma.
Thorax 1998;53(2):91-5.
1998: John M; Au B T; Jose P J; Lim S; Saunders M; Barnes P J; Mitchell J A; Belvisi M G; Chung K F
Expression and release of interleukin-8 by human airway smooth muscle cells: inhibition by Th-2 cytokines and corticosteroids.
American journal of respiratory cell and molecular biology 1998;18(1):84-90.
1998: John M; Lim S; Seybold J; Jose P; Robichaud A; O'Connor B; Barnes P J; Chung K F
Inhaled corticosteroids increase interleukin-10 but reduce macrophage inflammatory protein-1alpha, granulocyte-macrophage colony-stimulating factor, and interferon-gamma release from alveolar macrophages in asthma.
American journal of respiratory and critical care medicine 1998;157(1):256-62.
1998: Chung K F
The complementary role of glucocorticosteroids and long-acting beta-adrenergic agonists.
Allergy 1998;53(42 Suppl):7-13.
1997: Evans D J; Taylor D A; Zetterstrom O; Chung K F; O'Connor B J; Barnes P J
A comparison of low-dose inhaled budesonide plus theophylline and high-dose inhaled budesonide for moderate asthma.
The New England journal of medicine 1997;337(20):1412-8.
1997: Stone R A; Barnes P J; Chung K F
Effect of 5-HT1A receptor agonist, 8-OH-DPAT, on cough responses in the conscious guinea pig.
European journal of pharmacology 1997;332(2):201-7.
1997: Liu S F; Haddad E B; Adcock I; Salmon M; Koto H; Gilbey T; Barnes P J; Chung K F
Inducible nitric oxide synthase after sensitization and allergen challenge of Brown Norway rat lung.
British journal of pharmacology 1997;121(7):1241-6.
1997: Koto H; Salmon M; Haddad el-B; Huang T J; Zagorski J; Chung K F
Role of cytokine-induced neutrophil chemoattractant (CINC) in ozone-induced airway inflammation and hyperresponsiveness.
American journal of respiratory and critical care medicine 1997;156(1):234-9.
1997: Sun J; Chung K F
Interaction of ozone exposure with airway hyperresponsiveness and inflammation induced by trimellitic anhydride in sensitized guinea pigs.
Journal of toxicology and environmental health 1997;51(1):77-87.
1997: Al-Kattan K; Simonds A; Chung K F; Kaplan D K
Kyphoscoliosis and bronchial torsion.
Chest 1997;111(4):1134-7.
1997: Sun J; Koto H; Chung K F
Interaction of ozone and allergen challenges on bronchial responsiveness and inflammation in sensitised guinea pigs.
International archives of allergy and immunology 1997;112(2):191-5.
1997: John M; Hirst S J; Jose P J; Robichaud A; Berkman N; Witt C; Twort C H; Barnes P J; Chung K F
Human airway smooth muscle cells express and release RANTES in response to T helper 1 cytokines: regulation by T helper 2 cytokines and corticosteroids.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(4):1841-7.
1997: Sun J; Chung K F
Airway inflammation despite loss of bronchial hyper-responsiveness after multiple ozone exposures.
Respiratory medicine 1997;91(1):47-55.
1996: Berkman N; Krishnan V L; Gilbey T; Newton R; O'Connor B; Barnes P J; Chung K F
Expression of RANTES mRNA and protein in airways of patients with mild asthma.
American journal of respiratory and critical care medicine 1996;154(6 Pt 1):1804-11.
1996: Berkman N; Robichaud A; Robbins R A; Roesems G; Haddad E B; Barnes P J; Chung K F
Inhibition of inducible nitric oxide synthase expression by interleukin-4 and interleukin-13 in human lung epithelial cells.
Immunology 1996;89(3):363-7.
1996: Chung K F
Effects of nedocromil sodium on airway neurogenic mechanisms.
The Journal of allergy and clinical immunology 1996;98(5 Pt 2):S112-6; discussion S116-7.
1996: Lalloo U G; Barnes P J; Chung K F
Pathophysiology and clinical presentations of cough.
The Journal of allergy and clinical immunology 1996;98(5 Pt 2):S91-6; discussion S96-7.
1996: Chung K F
Methods of assessing cough and antitussives in man.
Pulmonary pharmacology 1996;9(5-6):373-7.
1996: Koto H; Mak J C; Haddad E B; Xu W B; Salmon M; Barnes P J; Chung K F
Mechanisms of impaired beta-adrenoceptor-induced airway relaxation by interleukin-1beta in vivo in the rat.
The Journal of clinical investigation 1996;98(8):1780-7.
1996: Berkman N; John M; Roesems G; Jose P; Barnes P J; Chung K F
Interleukin 13 inhibits macrophage inflammatory protein-1 alpha production from human alveolar macrophages and monocytes.
American journal of respiratory cell and molecular biology 1996;15(3):382-9.
1996: Adcock I M; Gilbey T; Gelder C M; Chung K F; Barnes P J
Glucocorticoid receptor localization in normal and asthmatic lung.
American journal of respiratory and critical care medicine 1996;154(3 Pt 1):771-82.
1996: Fox A J; Lalloo U G; Belvisi M G; Bernareggi M; Chung K F; Barnes P J
Bradykinin-evoked sensitization of airway sensory nerves: a mechanism for ACE-inhibitor cough.
Nature medicine 1996;2(7):814-7.
1996: Haczku A; Macary P; Haddad E B; Huang T J; Kemeny D M; Moqbel R; Chung K F
Expression of Th-2 cytokines interleukin-4 and -5 and of Th-1 cytokine interferon-gamma in ovalbumin-exposed sensitized Brown-Norway rats.
Immunology 1996;88(2):247-51.
1996: Kharitonov S A; Chung K F; Evans D; O'Connor B J; Barnes P J
Increased exhaled nitric oxide in asthma is mainly derived from the lower respiratory tract.
American journal of respiratory and critical care medicine 1996;153(6 Pt 1):1773-80.
1996: Gelder C M; Morrison J F; Chung K F; Barnes P J; Adcock I M
T cell receptor repertoire in peripheral blood and bronchial biopsies from normal and asthmatic subjects.
Biochemical Society transactions 1996;24(2):316S.
1996: Gelder C M; Barnes P J; O'Connor B J; Chung K F; Adcock I M
Cytokine mRNA profiles of normal and asthmatic peripheral blood cells and endobronchial biopsies.
Biochemical Society transactions 1996;24(2):315S.
1996: Berkman N; Robichaud A; Krishnan V L; Roesems G; Robbins R; Jose P J; Barnes P J; Chung K F
Expression of RANTES in human airway epithelial cells: effect of corticosteroids and interleukin-4, -10 and -13.
Immunology 1996;87(4):599-603.
1996: Chung K F
Theophylline in chronic asthma--evidence for disease-modifying properties.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1996;26 Suppl 2():22-7.
1996: Sakamoto T; Barnes P J; Chung K F
Lack of a role for bradykinin in allergen-induced airway microvascular leakage and bronchoconstriction in the guinea pig.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1996;45(3):123-6.
1996: Kharitonov S A; Yates D H; Chung K F; Barnes P J
Changes in the dose of inhaled steroid affect exhaled nitric oxide levels in asthmatic patients.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1996;9(2):196-201.
1996: Haddad E B; Salmon M; Koto H; Barnes P J; Adcock I; Chung K F
Ozone induction of cytokine-induced neutrophil chemoattractant (CINC) and nuclear factor-kappa b in rat lung: inhibition by corticosteroids.
FEBS letters 1996;379(3):265-8.
1996: Kidney J C; Lotvall J O; Lei Y; Chung K F; Barnes P J
The effect of inhaled K+ channel openers on bronchoconstriction and airway microvascular leakage in anaesthetised guinea pigs.
European journal of pharmacology 1996;296(1):81-7.
1995: Cambrey A D; Kwon O J; Gray A J; Harrison N K; Yacoub M; Barnes P J; Laurent G J; Chung K F
Insulin-like growth factor I is a major fibroblast mitogen produced by primary cultures of human airway epithelial cells.
Clinical science (London, England : 1979) 1995;89(6):611-7.
1995: Yates D H; O'Connor B J; Yilmaz G; Aikman S; Worsdell M; Barnes P J; Chung K F
Effect of acute and chronic inhaled furosemide on bronchial hyperresponsiveness in mild asthma.
American journal of respiratory and critical care medicine 1995;152(6 Pt 1):2173-5.
1995: Xu W B; Haddad E B; Tsukagoshi H; Adcock I; Barnes P J; Chung K F
Induction of macrophage inflammatory protein 2 gene expression by interleukin 1 beta in rat lung.
Thorax 1995;50(11):1136-40.
1995: Berkman N; John M; Roesems G; Jose P J; Barnes P J; Chung K F
Inhibition of macrophage inflammatory protein-1 alpha expression by IL-10. Differential sensitivities in human blood monocytes and alveolar macrophages.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(9):4412-8.
1995: Haddad E B; Liu S F; Salmon M; Robichaud A; Barnes P J; Chung K F
Expression of inducible nitric oxide synthase mRNA in Brown Norway rats exposed to ozone: effect of dexamethasone.
European journal of pharmacology 1995;293(3):287-90.
1995: Lalloo U G; Fox A J; Belvisi M G; Chung K F; Barnes P J
Capsazepine inhibits cough induced by capsaicin and citric acid but not by hypertonic saline in guinea pigs.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;79(4):1082-7.
1995: Yates D H; Sussman H S; Shaw M J; Barnes P J; Chung K F
Regular formoterol treatment in mild asthma. Effect on bronchial responsiveness during and after treatment.
American journal of respiratory and critical care medicine 1995;152(4 Pt 1):1170-4.
1995: Berkman N; Jose P J; Williams T J; Schall T J; Barnes P J; Chung K F
Corticosteroid inhibition of macrophage inflammatory protein-1 alpha in human monocytes and alveolar macrophages.
The American journal of physiology 1995;269(4 Pt 1):L443-52.
1995: Sun J; Sakamoto T; Chung K F
Effects of sodium metabisulphite on guinea pig contractile airway smooth muscle responses in vitro.
Thorax 1995;50(8):875-9.
1995: Haczku A; Chung K F; Sun J; Barnes P J; Kay A B; Moqbel R
Airway hyperresponsiveness, elevation of serum-specific IgE and activation of T cells following allergen exposure in sensitized Brown-Norway rats.
Immunology 1995;85(4):598-603.
1995: Haczku A; Moqbel R; Jacobson M; Kay A B; Barnes P J; Chung K F
T-cells subsets and activation in bronchial mucosa of sensitized Brown-Norway rats after single allergen exposure.
Immunology 1995;85(4):591-7.
1995: Chung K F
Leukotriene receptor antagonists and biosynthesis inhibitors: potential breakthrough in asthma therapy.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1995;8(7):1203-13.
1995: Tsukagoshi H; Haddad E B; Barnes P J; Chung K F
Bradykinin receptor subtypes in rat lung: effect of interleukin-1 beta.
The Journal of pharmacology and experimental therapeutics 1995;273(3):1257-63.
1995: Kidney J; Dominguez M; Taylor P M; Rose M; Chung K F; Barnes P J
Immunomodulation by theophylline in asthma. Demonstration by withdrawal of therapy.
American journal of respiratory and critical care medicine 1995;151(6):1907-14.
1995: Haddad E B; Salmon M; Sun J; Liu S; Das A; Adcock I; Barnes P J; Chung K F
Dexamethasone inhibits ozone-induced gene expression of macrophage inflammatory protein-2 in rat lung.
FEBS letters 1995;363(3):285-8.
1995: Tsukagoshi H; Sun J; Kwon O; Barnes P J; Chung K F
Role of neutral endopeptidase in bronchial hyperresponsiveness to bradykinin induced by IL-1 beta.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;78(3):921-7.
1995: Tsukagoshi H; Haddad E B; Sun J; Barnes P J; Chung K F
Ozone-induced airway hyperresponsiveness: role of superoxide anions, NEP, and BK receptors.
Journal of applied physiology (Bethesda, Md. : 1985) 1995;78(3):1015-22.
1995: Elwood W; Sun J; Barnes P J; Giembycz M A; Chung K F
Inhibition of allergen-induced lung eosinophilia by type-III and combined type III- and IV-selective phosphodiesterase inhibitors in brown-Norway rats.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1995;44(2):83-6.
1995: Harrison N K; Dawes K E; Kwon O J; Barnes P J; Laurent G J; Chung K F
Effects of neuropeptides on human lung fibroblast proliferation and chemotaxis.
The American journal of physiology 1995;268(2 Pt 1):L278-83.
1995: Hayes J P; Kuo H P; Rohde J A; Newman Taylor A J; Barnes P J; Chung K F; Rogers D F
Neurogenic goblet cell secretion and bronchoconstriction in guinea pigs sensitised to trimellitic anhydride.
European journal of pharmacology 1995;292(2):127-34.
1994: O'Connor B J; Yeo C T; Chen-Worsdell Y M; Barnes P J; Chung K F
Effect of acetazolamide and amiloride against sodium metabisulphite-induced bronchoconstriction in mild asthma.
Thorax 1994;49(11):1096-8.
1994: Kwon O J; Au B T; Collins P D; Adcock I M; Mak J C; Robbins R R; Chung K F; Barnes P J
Tumor necrosis factor-induced interleukin-8 expression in cultured human airway epithelial cells.
The American journal of physiology 1994;267(4 Pt 1):L398-405.
1994: Tsukagoshi H; Robbins R A; Barnes P J; Chung K F
Role of nitric oxide and superoxide anions in interleukin-1 beta-induced airway hyperresponsiveness to bradykinin.
American journal of respiratory and critical care medicine 1994;150(4):1019-25.
1994: O'Connor B J; Uden S; Carty T J; Eskra J D; Barnes P J; Chung K F
Inhibitory effect of UK,74505, a potent and specific oral platelet activating factor (PAF) receptor antagonist, on airway and systemic responses to inhaled PAF in humans.
American journal of respiratory and critical care medicine 1994;150(1):35-40.
1994: Haczku A; Moqbel R; Elwood W; Sun J; Kay A B; Barnes P J; Chung K F
Effects of prolonged repeated exposure to ovalbumin in sensitized brown Norway rats.
American journal of respiratory and critical care medicine 1994;150(1):23-7.
1994: Hsu J Y; Stone R A; Logan-Sinclair R B; Worsdell M; Busst C M; Chung K F
Coughing frequency in patients with persistent cough: assessment using a 24 hour ambulatory recorder.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1994;7(7):1246-53.
1994: Sun J; Elwood W; Haczku A; Barnes P J; Hellewell P G; Chung K F
Contribution of intercellular-adhesion molecule-1 in allergen-induced airway hyperresponsiveness and inflammation in sensitised brown-Norway rats.
International archives of allergy and immunology 1994;104(3):291-5.
1994: O'Connor B J; Barnes P J; Chung K F
Inhibition of sodium metabisulphite induced bronchoconstriction by frusemide in asthma: role of cyclooxygenase products.
Thorax 1994;49(4):307-11.
1994: Kwon O J; Au B T; Collins P D; Baraniuk J N; Adcock I M; Chung K F; Barnes P J
Inhibition of interleukin-8 expression by dexamethasone in human cultured airway epithelial cells.
Immunology 1994;81(3):389-94.
1994: Nichol G M; Parsons G H; Chung K F
Effect of sodium metabisulphite on bronchial blood flow in conscious sheep: pharmacological modulation.
British journal of pharmacology 1994;111(3):918-22.
1994: Sakamoto T; Tsukagoshi H; Barnes P J; Chung K F
Involvement of tachykinin receptors (NK1 and NK2) in sodium metabisulfite-induced airway effects.
American journal of respiratory and critical care medicine 1994;149(2 Pt 1):387-91.
1994: Tsukagoshi H; Sakamoto T; Xu W; Barnes P J; Chung K F
Effect of interleukin-1 beta on airway hyperresponsiveness and inflammation in sensitized and nonsensitized Brown-Norway rats.
The Journal of allergy and clinical immunology 1994;93(2):464-9.
1994: Sakamoto T; Sun J; Barnes P J; Chung K F
Effect of a bradykinin receptor antagonist, HOE 140, against bradykinin- and vagal stimulation-induced airway responses in the guinea-pig.
European journal of pharmacology 1994;251(2-3):137-42.
1994: Elwood W; Sakamoto T; Barnes P J; Chung K F
Role of cyclooxygenase and 5-lipoxygenase metabolites, platelet-activating factor and 5-hydroxytryptamine in allergen-induced airway responses in the brown Norway rat.
International archives of allergy and immunology 1994;103(1):67-72.
1994: Chung K F
Furosemide and other diuretics in asthma.
The Journal of asthma : official journal of the Association for the Care of Asthma 1994;31(2):85-92.
1993: Sun J; Elwood W; Barnes P J; Chung K F
Effect of thiazide diuretics against neurally mediated contraction of guinea pig airways. Contribution of carbonic anhydrase.
The American review of respiratory disease 1993;148(4 Pt 1):902-8.
1993: Hayes J P; Barnes P J; Taylor A J; Chung K F
Effect of a topical corticosteroid on airway hyperresponsiveness and eosinophilic inflammation induced by trimellitic anhydride exposure in sensitized guinea pigs.
The Journal of allergy and clinical immunology 1993;92(3):450-6.
1993: Sakamoto T; Barnes P J; Chung K F
Effect of beta 2-adrenoceptor agonists against platelet-activating factor-induced airway microvascular leakage and bronchoconstriction in the guinea pig.
Agents and actions 1993;40(1-2):50-6.
1993: Elwood W; Sakamoto T; Barnes P J; Chung K F
Allergen-induced airway hyperresponsiveness in Brown-Norway rat: role of parasympathetic mechanisms.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;75(1):279-84.
1993: Sakamoto T; Tsukagoshi H; Barnes P J; Chung K F
Role played by NK2 receptor and cyclooxygenase activation in bradykinin B2 receptor mediated-airway effects in guinea pigs.
Agents and actions 1993;39(3-4):111-7.
1993: Stone R A; Barnes P J; Chung K F
Effect of frusemide on cough responses to chloride-deficient solution in normal and mild asthmatic subjects.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1993;6(6):862-7.
1993: Kroegel C; Dewar A; Yukawa T; Venge P; Barnes P J; Chung K F
Ultrastructural characterization of platelet-activating factor-stimulated human eosinophils from patients with asthma.
Clinical science (London, England : 1979) 1993;84(4):391-9.
1993: Sakamoto T; Elwood W; Barnes P J; Chung K F
Effect of inhaled lyso-platelet-activating factor on airway microvascular leakage in the guinea pig.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;74(3):1117-22.
1993: Elwood W; Lötvall J O; Barnes P J; Chung K F
Airway hyperresponsiveness to acetylcholine and to tachykinins after respiratory virus infection in the guinea pig.
Annals of allergy 1993;70(3):231-6.
1993: Kidney J C; Fuller R W; Worsdell Y M; Lavender E A; Chung K F; Barnes P J
Effect of an oral potassium channel activator, BRL 38227, on airway function and responsiveness in asthmatic patients: comparison with oral salbutamol.
Thorax 1993;48(2):130-3.
1993: Evans P M; O'Connor B J; Fuller R W; Barnes P J; Chung K F
Effect of inhaled corticosteroids on peripheral blood eosinophil counts and density profiles in asthma.
The Journal of allergy and clinical immunology 1993;91(2):643-50.
1993: Kidney J C; Ridge S M; Chung K F; Barnes P J
Inhibition of platelet-activating factor-induced bronchoconstriction by the leukotriene D4 receptor antagonist ICI 204,219.
The American review of respiratory disease 1993;147(1):215-7.
1993: Sakamoto T; Barnes P J; Chung K F
Effect of CP-96,345, a non-peptide NK1 receptor antagonist, against substance P-, bradykinin- and allergen-induced airway microvascular leakage and bronchoconstriction in the guinea pig.
European journal of pharmacology 1993;231(1):31-8.
1992: Hayes J P; Daniel R; Tee R D; Barnes P J; Taylor A J; Chung K F
Bronchial hyperreactivity after inhalation of trimellitic anhydride dust in guinea pigs after intradermal sensitization to the free hapten.
The American review of respiratory disease 1992;146(5 Pt 1):1311-4.
1992: Hayes J P; Lotvall J O; Baraniuk J; Daniel R; Barnes P J; Taylor A J; Chung K F
Bronchoconstriction and airway microvascular leakage in guinea pigs sensitized with trimellitic anhydride.
The American review of respiratory disease 1992;146(5 Pt 1):1306-10.
1992: Sakamoto T; Elwood W; Barnes P J; Chung K F
Pharmacological modulation of inhaled sodium metabisulphite-induced airway microvascular leakage and bronchoconstriction in the guinea-pig.
British journal of pharmacology 1992;107(2):481-7.
1992: Hayes J P; Lotvall J O; Barnes P J; Newman Taylor A J; Chung K F
Involvement of inflammatory mediators in the airway responses to trimellitic anhydride in sensitized guinea-pigs.
British journal of pharmacology 1992;106(4):828-32.
1992: Hayes J P; Daniel R; Tee R D; Barnes P J; Chung K F; Newman Taylor A J
Specific immunological and bronchopulmonary responses following intradermal sensitization to free trimellitic anhydride in guinea pigs.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1992;22(7):694-700.
1992: Parsons G H; Villablanca A C; Brock J M; Howard R S; Colbert S R; Nichol G M; Chung K F
Bronchial vasodilation by histamine in sheep: characterization of receptor subtype.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;72(6):2090-8.
1992: Elwood W; Lötvall J O; Barnes P J; Chung K F
Effect of dexamethasone and cyclosporin A on allergen-induced airway hyperresponsiveness and inflammatory cell responses in sensitized Brown-Norway rats.
The American review of respiratory disease 1992;145(6):1289-94.
1992: Lötvall J; Elwood W; Tokuyama K; Sakamoto T; Barnes P J; Chung K F
A thromboxane mimetic, U-46619, produces plasma exudation in airways of the guinea pig.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;72(6):2415-9.
1992: Perkins R S; Dent G; Chung K F; Barnes P J
The effect of anion transport inhibitors and extracellular Cl- concentration on eosinophil respiratory burst activity.
Biochemical pharmacology 1992;43(11):2480-3.
1992: Ventresca P G; Nichol G M; Barnes P J; Chung K F
Effect of frusemide on the induction and potentiation of cough induced by prostaglandin F2 alpha.
British journal of clinical pharmacology 1992;33(5):514-6.
1992: Hui K P; Ventresca P; Brown A C; Barnes P J; Chung K F
Modulation of neurally mediated airway microvascular leakage in guinea-pig airways by beta 2-adrenoceptor agonists.
Agents and actions 1992;36(1-2):29-32.
1992: Parsons G H; Nichol G M; Barnes P J; Chung K F
Peptide mediator effects on bronchial blood velocity and lung resistance in conscious sheep.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;72(3):1118-22.
1992: Sakamoto T; Elwood W; Barnes P J; Chung K F
Effect of Hoe 140, a new bradykinin receptor antagonist, on bradykinin- and platelet-activating factor-induced bronchoconstriction and airway microvascular leakage in guinea pig.
European journal of pharmacology 1992;213(3):367-73.
1992: Chung K F
Mechanisms of bronchial inflammation in asthma: implications for therapy.
Schweizerische medizinische Wochenschrift 1992;122(9):288-93.
1992: Chung K F; Durham S R
Asthma as an inflammatory disease: clinical perspectives.
British medical bulletin 1992;48(1):179-89.
1992: Chung K F; Barnes P J
Role of inflammatory mediators in asthma.
British medical bulletin 1992;48(1):135-48.
1992: Lötvall J; Rabe K; Tokuyama K; Löfdahl C G; Barnes P J; Chung K F
Neutrophil influx into guinea-pig airway lumen during cholinergic and non-cholinergic bronchoconstriction.
Acta physiologica Scandinavica 1992;144(1):101-6.
1992: Chung K F; Barnes P J
Loop diuretics and asthma.
Pulmonary pharmacology 1992;5(1):1-7.
1992: Elwood W; Barnes P J; Chung K F
Airway hyperresponsiveness is associated with inflammatory cell infiltration in allergic brown-Norway rats.
International archives of allergy and immunology 1992;99(1):91-7.
1992: Nichol G M; O'Connor B J; Lecomte J M; Chung K F; Barnes P J
Effect of neutral endopeptidase inhibitor on airway function and bronchial responsiveness in asthmatic subjects.
European journal of clinical pharmacology 1992;42(5):491-4.
1991: Chung K F; Barnes P J
Role for platelet-activating factor in asthma.
Lipids 1991;26(12):1277-9.
1991: Elwood W; Lötvall J O; Barnes P J; Chung K F
Characterization of allergen-induced bronchial hyperresponsiveness and airway inflammation in actively sensitized brown-Norway rats.
The Journal of allergy and clinical immunology 1991;88(6):951-60.
1991: Lötvall J O; Elwood W; Tokuyama K; Barnes P J; Chung K F
Differential effects of phosphoramidon on neurokinin A- and substance P-induced airflow obstruction and airway microvascular leakage in guinea-pig.
British journal of pharmacology 1991;104(4):945-9.
1991: Tokuyama K; Lötvall J O; Morikawa A; Barnes P J; Chung K F
Role of thromboxane A2 in airway microvascular leakage induced by inhaled platelet-activating factor.
Journal of applied physiology (Bethesda, Md. : 1985) 1991;71(5):1729-34.
1991: Shock A; Rabe K F; Dent G; Chambers R C; Gray A J; Chung K F; Barnes P J; Laurent G J
Eosinophils adhere to and stimulate replication of lung fibroblasts 'in vitro'.
Clinical and experimental immunology 1991;86(1):185-90.
1991: Lötvall J O; Tokuyama K; Barnes P J; Chung K F
Bradykinin-induced airway microvascular leakage is potentiated by captopril and phosphoramidon.
European journal of pharmacology 1991;200(2-3):211-7.
1991: Hayes J P; Ridge S M; Griffith S; Barnes P J; Chung K F
Inhibition of cutaneous and platelet responses to platelet-activating factor by oral WEB 2086 in man.
The Journal of allergy and clinical immunology 1991;88(1):83-8.
1991: Tokuyama K; Lötvall J O; Barnes P J; Chung K F
Mechanism of airway narrowing caused by inhaled platelet-activating factor. Role of airway microvascular leakage.
The American review of respiratory disease 1991;143(6):1345-9.
1991: Elwood W; Lötvall J O; Barnes P J; Chung K F
Loop diuretics inhibit cholinergic and noncholinergic nerves in guinea pig airways.
The American review of respiratory disease 1991;143(6):1340-4.
1991: O'Connor B J; Chung K F; Chen-Worsdell Y M; Fuller R W; Barnes P J
Effect of inhaled furosemide and bumetanide on adenosine 5'-monophosphate- and sodium metabisulfite-induced bronchoconstriction in asthmatic subjects.
The American review of respiratory disease 1991;143(6):1329-33.
1991: Lötvall J O; Tokuyama K; Löfdahl C G; Ullman A; Barnes P J; Chung K F
Peptidase modulation of noncholinergic vagal bronchoconstriction and airway microvascular leakage.
Journal of applied physiology (Bethesda, Md. : 1985) 1991;70(6):2730-5.
1991: Hui K P; Lötvall J; Chung K F; Barnes P J
Attenuation of inhaled allergen-induced airway microvascular leakage and airflow obstruction in guinea pigs by a 5-lipoxygenase inhibitor (A-63162).
The American review of respiratory disease 1991;143(5 Pt 1):1015-9.
1991: Lötvall J O; Elwood W; Tokuyama K; Barnes P J; Chung K F
Plasma exudation into airways induced by inhaled platelet-activating factor: effect of peptidase inhibition.
Clinical science (London, England : 1979) 1991;80(3):241-7.
1991: Chung K F; Podgorski M R; Goulding N J; Godolphin J L; Sharland P R; O'Connor B; Flower R J; Barnes P J
Circulating autoantibodies to recombinant lipocortin-1 in asthma.
Respiratory medicine 1991;85(2):121-4.
1991: Lötvall J O; Hui K P; Löfdahl C G; Barnes P J; Chung K F
Capsaicin pretreatment does not inhibit allergen-induced airway microvascular leakage in guinea pig.
Allergy 1991;46(2):105-8.
1991: Tokuyama K; Lötvall J O; Löfdahl C G; Barnes P J; Chung K F
Inhaled formoterol inhibits histamine-induced airflow obstruction and airway microvascular leakage.
European journal of pharmacology 1991;193(1):35-9.
1991: Rabe K F; Chung K F
The challenge of long-acting beta-adrenoceptor agonists.
Respiratory medicine 1991;85(1):5-9.
1990: Lötvall J O; Skoogh B E; Lemen R J; Elwood W; Barnes P J; Chung K F
Bronchoconstriction induced by inhaled sodium metabisulfite in the guinea pig. Effect of capsaicin pretreatment and of neutral endopeptidase inhibition.
The American review of respiratory disease 1990;142(6 Pt 1):1390-5.
1990: Barnes P J; Boschetto P; Rogers D F; Belvisi M; Roberts N; Chung K F; Evans T W
Effects of treatment on airway microvascular leakage.
The European respiratory journal. Supplement 1990;12():663s-670s; discussion 670s-671s.
1990: Chanez P; Dent G; Yukawa T; Barnes P J; Chung K F
Generation of oxygen free radicals from blood eosinophils from asthma patients after stimulation with PAF or phorbol ester.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1990;3(9):1002-7.
1990: Lötvall J O; Lemen R J; Hui K P; Barnes P J; Chung K F
Airflow obstruction after substance P aerosol: contribution of airway and pulmonary edema.
Journal of applied physiology (Bethesda, Md. : 1985) 1990;69(4):1473-8.
1990: Chung K F
Mediators of bronchial hyperresponsiveness.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1990;20(5):453-8.
1990: Nichol G M; Alton E W; Nix A; Geddes D M; Chung K F; Barnes P J
Effect of inhaled furosemide on metabisulfite- and methacholine-induced bronchoconstriction and nasal potential difference in asthmatic subjects.
The American review of respiratory disease 1990;142(3):576-80.
1990: Nichol G; Nix A; Barnes P J; Chung K F
Prostaglandin F2 alpha enhancement of capsaicin induced cough in man: modulation by beta 2 adrenergic and anticholinergic drugs.
Thorax 1990;45(9):694-8.
1990: Ventresca P G; Nichol G M; Barnes P J; Chung K F
Inhaled furosemide inhibits cough induced by low chloride content solutions but not by capsaicin.
The American review of respiratory disease 1990;142(1):143-6.
1990: Yukawa T; Ukena D; Kroegel C; Chanez P; Dent G; Chung K F; Barnes P J
Beta 2-adrenergic receptors on eosinophils. Binding and functional studies.
The American review of respiratory disease 1990;141(6):1446-52.
1990: Yukawa T; Read R C; Kroegel C; Rutman A; Chung K F; Wilson R; Cole P J; Barnes P J
The effects of activated eosinophils and neutrophils on guinea pig airway epithelium in vitro.
American journal of respiratory cell and molecular biology 1990;2(4):341-53.
1990: Lammers J W; Kioumis I; McCusker M; Nichol G M; Barnes P J; Chung K F
Effects of prostacyclin on bronchoconstriction and neutropenia induced by inhaled platelet-activating factor in man.
The Journal of allergy and clinical immunology 1990;85(4):763-9.
1990: Evans T W; McAnulty R J; Rogers D F; Chung K F; Barnes P J; Laurent G J
Bleomycin-induced lung injury in the rat: effects of the platelet-activating factor (PAF) receptor antagonist BN 52021 and platelet depletion.
Environmental health perspectives 1990;85():65-9.
1990: Chung K F; Rogers D F; Barnes P J; Evans T W
The role of increased airway microvascular permeability and plasma exudation in asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1990;3(3):329-37.
1990: Nix A; Nichol G M; Robson A; Barnes P J; Chung K F
Effect of formoterol, a long-lasting beta 2-adrenoceptor agonist, against methacholine-induced bronchoconstriction.
British journal of clinical pharmacology 1990;29(3):321-4.
1990: Wardlaw A J; Chung K F; Moqbel R; MacDonald A J; Hartnell A; McCusker M; Collins J V; Barnes P J; Kay A B
Effects of inhaled PAF in humans on circulating and bronchoalveolar lavage fluid neutrophils. Relationship to bronchoconstriction and changes in airway responsiveness.
The American review of respiratory disease 1990;141(2):386-92.
1990: Chung K F
Pharmacology of airway inflammation in asthma.
Lung 1990;168 Suppl():132-41.
1989: Nichol G M; Nix A; Chung K F; Barnes P J
Characterisation of bronchoconstrictor responses to sodium metabisulphite aerosol in atopic subjects with and without asthma.
Thorax 1989;44(12):1009-14.
1989: Yukawa T; Kroegel C; Evans P; Fukuda T; Chung K F; Barnes P J
Density heterogeneity of eosinophil leucocytes: induction of hypodense eosinophils by platelet-activating factor.
Immunology 1989;68(1):140-3.
1989: Chung K F; Cuss F M; Barnes P J
Platelet activating factor: effects on bronchomotor tone and bronchial responsiveness in human beings.
Allergy proceedings : the official journal of regional and state allergy societies 1989;10(5):333-7.
1989: Chung K F; Lammers J W; McCusker M; Roberts N M; Nichol G M; Barnes P J
Effect of theophylline on airway responses to inhaled platelet-activating factor in man.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1989;2(8):763-8.
1989: Yukawa T; Kroegel C; Chanez P; Dent G; Ukena D; Chung K F; Barnes P J
Effect of theophylline and adenosine on eosinophil function.
The American review of respiratory disease 1989;140(2):327-33.
1989: Lammers J W; Minette P; McCusker M T; Chung K F; Barnes P J
Capsaicin-induced bronchodilation in mild asthmatic subjects: possible role of nonadrenergic inhibitory system.
Journal of applied physiology (Bethesda, Md. : 1985) 1989;67(2):856-61.
1989: McCusker M T; Chung K F; Roberts N M; Barnes P J
Effect of topical capsaicin on the cutaneous responses to inflammatory mediators and to antigen in man.
The Journal of allergy and clinical immunology 1989;83(6):1118-24.
1989: Kroegel C; Yukawa T; Dent G; Venge P; Chung K F; Barnes P J
Stimulation of degranulation from human eosinophils by platelet-activating factor.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(10):3518-26.
1989: Chung K F; Barnes P J
Effects of platelet activating factor on airway calibre, airway responsiveness, and circulating cells in asthmatic subjects.
Thorax 1989;44(2):108-15.
1989: Chung K F; Dent G; Barnes P J
Effects of salbutamol on bronchoconstriction, bronchial hyperresponsiveness, and leucocyte responses induced by platelet activating factor in man.
Thorax 1989;44(2):102-7.
1989: Kroegel C; Pleass R; Yukawa T; Chung K F; Westwick J; Barnes P J
Characterization of platelet-activating factor-induced elevation of cytosolic free calcium concentration in eosinophils.
FEBS letters 1989;243(1):41-6.
1988: Belvisi M G; Chung K F; Jackson D M; Barnes P J
Opioid modulation of non-cholinergic neural bronchoconstriction in guinea-pig in vivo.
British journal of pharmacology 1988;95(2):413-8.
1988: Kioumis I; Lammers J W; Dent G; Chung K F; Barnes P J
Effect of inhaled platelet-activating factor on circulating neutrophils and platelets in vivo and ex vivo in man.
Prostaglandins 1988;36(3):343-54.
1988: Kroegel C; Yukawa T; Dent G; Chanez P; Chung K F; Barnes P J
Platelet-activating factor induces eosinophil peroxidase release from purified human eosinophils.
Immunology 1988;64(3):559-61.
1988: Roberts N M; McCusker M; Chung K F; Barnes P J
Effect of a PAF antagonist, BN52063, on PAF-induced bronchoconstriction in normal subjects.
British journal of clinical pharmacology 1988;26(1):65-72.
1988: Chung K F; Minette P; McCusker M; Barnes P J
Ketotifen inhibits the cutaneous but not the airway responses to platelet-activating factor in man.
The Journal of allergy and clinical immunology 1988;81(6):1192-8.
1988: Barnes P J; Chung K F; Page C P
Platelet-activating factor as a mediator of allergic disease.
The Journal of allergy and clinical immunology 1988;81(5 Pt 1):919-34.
1988: Lammers J W; Minette P; McCusker M T; Chung K F; Barnes P J
Nonadrenergic bronchodilator mechanisms in normal human subjects in vivo.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;64(5):1817-22.
1988: Chung K F; Barnes P J
PAF antagonists. Their potential therapeutic role in asthma.
Drugs 1988;35(2):93-103.
1988: Chung K F; Barnes P J
Respiratory and allergic disease. II. Chronic obstructive airways disease and respiratory infections.
British medical journal (Clinical research ed.) 1988;296(6615):111-5.
1988: Chung K F; Barnes P J
Respiratory and allergic disease. I.
British medical journal (Clinical research ed.) 1988;296(6614):29-33.

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