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Maxey Chung

Research Profile

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Proteomics

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

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Sayaka Higuchi; Shashikant B Joshi; Teck Kwang Lim; Qingsong Lin; Michael P Sheetz; Jigang Wang; Ganesh Srinivasan Anand; Maxey C M Chung; Hideaki Fujita
Heart extracellular matrix supports cardiomyocyte differentiation of mouse embryonic stem cells.
Qian Hou; Avery Khoo; Kiat Hon Lim; Teck Kwang Lim; Hwee Tong Tan; Iain B H Tan; Khay Guan Yeoh; Maxey C M Chung
Identification and functional validation of caldesmon as a potential gastric cancer metastasis-associated protein.
Kim Y C Fung; Maxey C M Chung; Leah J Cosgrove; Tanya Lewanowitsch; Teck Kwang Lim; Qingsong Lin; TJ Lockett; Cheng Cheng Ooi; Hwee Tong Tan; Sandra Tan; Desmond B Williams; Richard J Head
Identification of potential pathways involved in induction of apoptosis by butyrate and 4-benzoylbutyrate in HT29 colorectal cancer cells.

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All Publications

2013: Sayaka Higuchi; Shashikant B Joshi; Teck Kwang Lim; Qingsong Lin; Michael P Sheetz; Jigang Wang; Ganesh Srinivasan Anand; Maxey C M Chung; Hideaki Fujita
Heart extracellular matrix supports cardiomyocyte differentiation of mouse embryonic stem cells.
Journal of bioscience and bioengineering 2013;115(3):320-5.
2013: Qian Hou; Avery Khoo; Kiat Hon Lim; Teck Kwang Lim; Hwee Tong Tan; Iain B H Tan; Khay Guan Yeoh; Maxey C M Chung
Identification and functional validation of caldesmon as a potential gastric cancer metastasis-associated protein.
Journal of proteome research 2013;12(2):980-90.
2012: Kim Y C Fung; Maxey C M Chung; Leah J Cosgrove; Tanya Lewanowitsch; Teck Kwang Lim; Qingsong Lin; TJ Lockett; Cheng Cheng Ooi; Hwee Tong Tan; Sandra Tan; Desmond B Williams; Richard J Head
Identification of potential pathways involved in induction of apoptosis by butyrate and 4-benzoylbutyrate in HT29 colorectal cancer cells.
Journal of proteome research 2012;11(12):6019-29.
2012: Hwee Tong Tan; Yie Hou Lee; Maxey C M Chung
Cancer proteomics.
Mass spectrometry reviews 2012;31(5):583-605.
2012: Wei Wu; Khay Guan Yeoh; Wen Chun Juan; Cynthia R M Y Liang; Jimmy B Y So; Maxey C M Chung
S100A9, GIF and AAT as potential combinatorial biomarkers in gastric cancer diagnosis and prognosis.
Proteomics. Clinical applications 2012;6(3-4):152-62.
2012: Hendrick Loei; Jimmy Bok-Yan So; Hwee Tong Tan; Khay Guan Yeoh; Kiat Hon Lim; Teck Kwang Lim; Maxey C M Chung
Mining the gastric cancer secretome: identification of GRN as a potential diagnostic marker for early gastric cancer.
Journal of proteome research 2012;11(3):1759-72.
2012: Hwee Tong Tan; Sandra Tan; Wei Wu; Benedict Yan; Xuxiao Zhang; Shing Chuan Hooi; Yi Zhen Ng; Chee Wee Ong; Manuel Salto-Tellez; Maxey C M Chung
Proteomic analysis of colorectal cancer metastasis: stathmin-1 revealed as a player in cancer cell migration and prognostic marker.
Journal of proteome research 2012;11(2):1433-45.
2012: Wilson Wen Bin Goh; Yie Hou Lee; Zubaidah M Ramdzan; Maxey C M Chung; Limsoon Wong; Marek Sergot
A network-based maximum link approach towards MS identifies potentially important roles for undetected ARRB1/2 and ACTB in liver cancer progression.
International journal of bioinformatics research and applications 2012;8(3-4):155-70.
2012: Cynthia Liang; Gek San Tan; Maxey C M Chung
2D DIGE analysis of serum after fractionation by ProteoMiner™ beads.
Methods in molecular biology (Clifton, N.J.) 2012;854():181-94.
2012: Egisto Boschetti; Maxey C M Chung; Pier Giorgio Righetti
"The quest for biomarkers": are we on the right technical track?
Proteomics. Clinical applications 2012;6(1-2):22-41.
2011: Francesco Di Girolamo; Pier Giorgio Righetti; Alfonsina D'Amato; Maxey C M Chung
Cibacron Blue and proteomics: the mystery of the platoon missing in action.
Journal of proteomics 2011;74(12):2856-65.
2011: Dipanjana Ghosh; Teck Kwang Lim; Maxey C M Chung; Hwee Tong Tan; Xing Fei Tan; Han Yu; Ramdzan M Zubaidah; Qingsong Lin
Identification of key players for colorectal cancer metastasis by iTRAQ quantitative proteomics profiling of isogenic SW480 and SW620 cell lines.
Journal of proteome research 2011;10(10):4373-87.
2011: Wilson Wen Bin Goh; Yie Hou Lee; Ramdzan M Zubaidah; Jingjing Jin; Difeng Dong; Qingsong Lin; Maxey C M Chung; Limsoon Wong
Network-based pipeline for analyzing MS data: an application toward liver cancer.
Journal of proteome research 2011;10(5):2261-72.
2011: Francesco Di Girolamo; Egisto Boschetti; Maxey C M Chung; Fiorella Guadagni; Pier Giorgio Righetti
"Proteomineering" or not? The debate on biomarker discovery in sera continues.
Journal of proteomics 2011;74(5):589-94.
2011: Francesco Di Girolamo; Kumar Bala; Maxey C M Chung; Pier Giorgio Righetti
"Proteomineering" serum biomarkers. A study in scarlet.
Electrophoresis 2011;32(9):976-80.
2011: Hwee Tong Tan; Teck Kwang Lim; Maxey C M Chung; Qingsong Lin
iTRAQ™ labeling coupled with LC-MALDI mass spectrometry for monitoring temporal response of colorectal cancer cells to butyrate treatment.
Methods in molecular biology (Clifton, N.J.) 2011;716():207-24.
2010: Yie Hou Lee; Hugh T-W Tan; Maxey C M Chung
Subcellular fractionation methods and strategies for proteomics.
Proteomics 2010;10(22):3935-56.
2010: Cynthia R M Y Liang; Sandra Tan; Hugh T-W Tan; Qingsong Lin; Teck Kwang Lim; Yi Liu; Khay Guan Yeoh; Jimmy B Y So; Maxey C M Chung
Proteomic analysis of human gastric juice: a shotgun approach.
Proteomics 2010;10(21):3928-31.
2010: Yie Hou Lee; Qingsong Lin; Urs A Boelsterli; Maxey C M Chung
The Sod2 mutant mouse as a model for oxidative stress: a functional proteomics perspective.
Mass spectrometry reviews 2010;29(2):179-96.
2010: Fuchu He; Maxey C M Chung; T William Jordan
Chinese human liver proteome project: a pathfinder of HUPO human liver proteome project.
Journal of proteome research 2010;9(1):1-2.
2010: Jinghui Jia; Jingyu Wang; Ming Teh; Wei Sun; Jianhua Zhang; Irene Kee; Pierce Chow; Rosa Cynthia M Y Liang; Maxey C M Chung; Ruowen Ge
Identification of proteins differentially expressed between capillary endothelial cells of hepatocellular carcinoma and normal liver in an orthotopic rat tumor model using 2-D DIGE.
Proteomics 2010;10(2):224-34.
2009: Hugh T-W Tan; Jiayi Low; Seng Gee Lim; Maxey C M Chung
Serum autoantibodies as biomarkers for early cancer detection.
The FEBS journal 2009;276(23):6880-904.
2008: Sandra Tan; Hwee Tong Tan; Maxey C M Chung
Membrane proteins and membrane proteomics.
Proteomics 2008;8(19):3924-32.
2008: Yie Hou Lee; Maxey C M Chung; Qingsong Lin; Urs A Boelsterli
Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2(+/-) mice: two-stage oxidative injury.
Toxicology and applied pharmacology 2008;231(1):43-51.
2008: Hwee Tong Tan; Sandra Tan; Qingsong Lin; Teck Kwang Lim; Choy L Hew; Maxey C M Chung
Quantitative and temporal proteome analysis of butyrate-treated colorectal cancer cells.
Molecular & cellular proteomics : MCP 2008;7(6):1174-85.
2008: Yie Hou Lee; Urs A Boelsterli; Qingsong Lin; Maxey C M Chung
Proteomics profiling of hepatic mitochondria in heterozygous Sod2+/- mice, an animal model of discreet mitochondrial oxidative stress.
Proteomics 2008;8(3):555-68.
2007: Guo Dong Lu; Han-Ming Shen; Maxey C M Chung; Choon-Nam Ong
Critical role of oxidative stress and sustained JNK activation in aloe-emodin-mediated apoptotic cell death in human hepatoma cells.
Carcinogenesis 2007;28(9):1937-45.
2007: Qing Huang; Guodong Lu; Han-Ming Shen; Maxey C M Chung; Choon-Nam Ong
Anti-cancer properties of anthraquinones from rhubarb.
Medicinal research reviews 2007;27(5):609-30.
2007: Sandra Tan; Cynthia R M Y Liang; Khay Guan Yeoh; Jimmy So; Choy Leong Hew; Maxey C M Chung
Gastrointestinal fluids proteomics.
Proteomics. Clinical applications 2007;1(8):820-33.
2007: Huoming Zhang; Qingsong Lin; Sukumar Ponnusamy; Narasimhan Kothandaraman; Teck Kwang Lim; Changqing Zhao; Hon Sook Kit; Biswas Arijit; Mary Rauff; Choy L Hew; Maxey C M Chung; Shashikant B Joshi; Mahesh Choolani
Differential recovery of membrane proteins after extraction by aqueous methanol and trifluoroethanol.
Proteomics 2007;7(10):1654-63.
2007: Guo Dong Lu; Han-Ming Shen; Choon-Nam Ong; Maxey C M Chung
Anticancer effects of aloe-emodin on HepG2 cells: Cellular and proteomic studies.
Proteomics. Clinical applications 2007;1(4):410-9.
2006: Hwee Tong Tan; Ramdzan M Zubaidah; Sandra Tan; Shing Chuan Hooi; Maxey C M Chung
2-D DIGE analysis of butyrate-treated HCT-116 cells after enrichment with heparin affinity chromatography.
Journal of proteome research 2006;5(5):1098-106.
2006: Peter Nissom; Siaw Ling Lo; Jennifer Chi Yi Lo; Peh Fern Ong; Justin Wee Eng Lim; Keli Ou; Rosa Cynthia M Y Liang; Teck Keong Seow; Maxey C M Chung
Hcc-2, a novel mammalian ER thioredoxin that is differentially expressed in hepatocellular carcinoma.
FEBS letters 2006;580(9):2216-26.
2006: Siaw Ling Lo; Tao You; Qingsong Lin; Shashikant B Joshi; Maxey C M Chung; Choy L Hew
SPLASH: systematic proteomics laboratory analysis and storage hub.
Proteomics 2006;6(6):1758-69.
2006: Marc R Wilkins; Ron D Appel; Jennifer E Van Eyk; Maxey C M Chung; Angelika Görg; Michael Hecker; Lukas A Huber; Hanno Langen; Andrew J Link; Young-Ki Paik; Scott D Patterson; Stephen R Pennington; Thierry Rabilloud; Richard J Simpson; Walter Weiss; Michael J Dunn
Guidelines for the next 10 years of proteomics.
Proteomics 2006;6(1):4-8.
2005: Cynthia R M Y Liang; Chon Kar Leow; Jason C H Neo; Gek San Tan; Siaw Ling Lo; Justin Wee Eng Lim; Teck Keong Seow; Paul B S Lai; Maxey C M Chung
Proteome analysis of human hepatocellular carcinoma tissues by two-dimensional difference gel electrophoresis and mass spectrometry.
Proteomics 2005;5(8):2258-71.
2005: Siaw Ling Lo; Cong Zhong Cai; Yu Zong Chen; Maxey C M Chung
Effect of training datasets on support vector machine prediction of protein-protein interactions.
Proteomics 2005;5(4):876-84.
2005: Jason C H Neo; Peter Rose; Choon-Nam Ong; Maxey C M Chung
beta-Phenylethyl isothiocyanate mediated apoptosis: a proteomic investigation of early apoptotic protein changes.
Proteomics 2005;5(4):1075-82.
2005: Palasingam Paaventhan; Chunguang Kong; Jeremiah S Joseph; Maxey C M Chung; Prasanna R Kolatkar
Structure of rhodocetin reveals noncovalently bound heterodimer interface.
Protein science : a publication of the Protein Society 2005;14(1):169-75.
2004: Teck Yew Low; Chon Kar Leow; Manuel Salto-Tellez; Maxey C M Chung
A proteomic analysis of thioacetamide-induced hepatotoxicity and cirrhosis in rat livers.
Proteomics 2004;4(12):3960-74.
2004: Xiaolei Li; Lu Zheng; Chunguang Kong; Prasanna R Kolatkar; Maxey C M Chung
Purpureotin: a novel di-dimeric C-type lectin-like protein from Trimeresurus purpureomaculatus venom is stabilized by noncovalent interactions.
Archives of biochemistry and biophysics 2004;424(1):53-62.
2004: Lian Yi Han; Cong Zhong Cai; Siaw Ling Lo; Maxey C M Chung; Yu Zong Chen
Prediction of RNA-binding proteins from primary sequence by a support vector machine approach.
RNA (New York, N.Y.) 2004;10(3):355-68.
2004: Rashmi Korke; Marcela de Leon Gatti; Ally Lei Yin Lau; Justin Wee Eng Lim; Teck Keong Seow; Maxey C M Chung; Wei-Shou Hu
Large scale gene expression profiling of metabolic shift of mammalian cells in culture.
Journal of biotechnology 2004;107(1):1-17.
2002: Teck Yew Low; Teck Keong Seow; Maxey C M Chung
Separation of human erythrocyte membrane associated proteins with one-dimensional and two-dimensional gel electrophoresis followed by identification with matrix-assisted laser desorption/ionization-time of flight mass spectrometry.
Proteomics 2002;2(9):1229-39.
2002: Rosa Cynthia M Y Liang; Jason C H Neo; Siaw Ling Lo; Gek San Tan; Teck Keong Seow; Maxey C M Chung
Proteome database of hepatocellular carcinoma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2002;771(1-2):303-28.
2002: Sandra Tan; Teck Keong Seow; Rosa Cynthia M Y Liang; Shiuan Koh; Christine P C Lee; Maxey C M Chung; Shing Chuan Hooi
Proteome analysis of butyrate-treated human colon cancer cells (HT-29).
International journal of cancer. Journal international du cancer 2002;98(4):523-31.
2002: Rashmi Korke; Anette Rink; Teck Keong Seow; Maxey C M Chung; Craig Warren Beattie; Wei-Shou Hu
Genomic and proteomic perspectives in cell culture engineering.
Journal of biotechnology 2002;94(1):73-92.
2002: Jeremiah S Joseph; Maxey C M Chung; Peter Mirtschin; R Manjunatha Kini
Effect of snake venom procoagulants on snake plasma: implications for the coagulation cascade of snakes.
Toxicon : official journal of the International Society on Toxinology 2002;40(2):175-83.
2001: R Wang; Chunguang Kong; Prasanna R Kolatkar; Maxey C M Chung
A novel dimer of a C-type lectin-like heterodimer from the venom of Calloselasma rhodostoma (Malayan pit viper).
FEBS letters 2001;508(3):447-53.
2001: Teck Keong Seow; Rashmi Korke; Rosa Cynthia M Y Liang; Shao-En Ong; Keli Ou; K Wong; Wei-Shou Hu; Maxey C M Chung
Proteomic investigation of metabolic shift in mammalian cell culture.
Biotechnology progress 2001;17(6):1137-44.
2001: Teck Keong Seow; Rosa Cynthia M Y Liang; Chon Kar Leow; Maxey C M Chung
Hepatocellular carcinoma: from bedside to proteomics.
Proteomics 2001;1(10):1249-63.
2001: Keli Ou; Teck Keong Seow; Rosa Cynthia M Y Liang; Bee Wah Lee; Denise Li-Meng Goh; Kaw Yan Chua; Maxey C M Chung
Identification of a serine protease inhibitor homologue in Bird's Nest by an integrated proteomics approach.
Electrophoresis 2001;22(16):3589-95.
2001: Keli Ou; Teck Keong Seow; Rosa Cynthia M Y Liang; Shao-En Ong; Maxey C M Chung
Proteome analysis of a human heptocellular carcinoma cell line, HCC-M: an update.
Electrophoresis 2001;22(13):2804-11.
2001: Chunguang Kong; Maxey C M Chung
Purification and characterization of a variant of rhodocetin from Calloselasma rhodostoma (Malayan pit viper) venom.
Journal of protein chemistry 2001;20(5):383-90.
2001: Meng Ling Choong; Li Kiang Tan; Siaw Ling Lo; Ee Chee Ren; Keli Ou; Shao-En Ong; Rosa Cynthia M Y Liang; Teck Keong Seow; Maxey C M Chung
An integrated approach in the discovery and characterization of a novel nuclear protein over-expressed in liver and pancreatic tumors.
FEBS letters 2001;496(2-3):109-16.
2000: Teck Keong Seow; Shao-En Ong; Rosa Cynthia M Y Liang; Ee Chee Ren; L Chan; Keli Ou; Maxey C M Chung
Two-dimensional electrophoresis map of the human hepatocellular carcinoma cell line, HCC-M, and identification of the separated proteins by mass spectrometry.
Electrophoresis 2000;21(9):1787-813.
1999: Jeremiah S Joseph; Maxey C M Chung; Kandiah Jeyaseelan; R Manjunatha Kini
Amino acid sequence of trocarin, a prothrombin activator from Tropidechis carinatus venom: its structural similarity to coagulation factor Xa.
Blood 1999;94(2):621-31.
1999: R Wang; R Manjunatha Kini; Maxey C M Chung
Rhodocetin, a novel platelet aggregation inhibitor from the venom of Calloselasma rhodostoma (Malayan pit viper): synergistic and noncovalent interaction between its subunits.
Biochemistry 1999;38(23):7584-93.
1997: G S Gendeh; Maxey C M Chung; Kandiah Jeyaseelan
Genomic structure of a potassium channel toxin from Heteractis magnifica.
FEBS letters 1997;418(1-2):183-8.
1997: G S Gendeh; Louise C Young; CL de Medeiros; Kandiah Jeyaseelan; Alan L Harvey; Maxey C M Chung
A new potassium channel toxin from the sea anemone Heteractis magnifica: isolation, cDNA cloning, and functional expression.
Biochemistry 1997;36(38):11461-71.
1997: M Z Huang; Ponnampalam Gopalakrishnakone; Maxey C M Chung; R Manjunatha Kini
Complete amino acid sequence of an acidic, cardiotoxic phospholipase A2 from the venom of Ophiophagus hannah (King Cobra): a novel cobra venom enzyme with "pancreatic loop".
Archives of biochemistry and biophysics 1997;338(2):150-6.
1996: FJ Ghadessy; D Chen; R Manjunatha Kini; Maxey C M Chung; Kandiah Jeyaseelan; Hoon Eng Khoo; R Yuen
Stonustoxin is a novel lethal factor from stonefish (Synanceja horrida) venom. cDNA cloning and characterization.
The Journal of biological chemistry 1996;271(41):25575-81.
1996: Maxey C M Chung; G Ponnudurai; M Kataoka; S Shimizu; Nget-Hong Tan
Structural studies of a major hemorrhagin (rhodostoxin) from the venom of Calloselasma rhodostoma (Malayan pit viper).
Archives of biochemistry and biophysics 1996;325(2):199-208.
1994: FJ Ghadessy; Kandiah Jeyaseelan; Maxey C M Chung; Hoon Eng Khoo; R Yuen
A genomic region encoding stonefish (Synanceja horrida) stonustoxin beta-subunit contains an intron.
Toxicon : official journal of the International Society on Toxinology 1994;32(12):1684-8.
1994: Maxey C M Chung; Nget-Hong Tan; Arunmozhiarasi Armugam
The amino acid sequences of two postsynaptic neurotoxins isolated from Malayan cobra (Naja naja sputatrix) venom.
Toxicon : official journal of the International Society on Toxinology 1994;32(11):1471-4.
1994: G Ponnudurai; Maxey C M Chung; Nget-Hong Tan
Purification and properties of the L-amino acid oxidase from Malayan pit viper (Calloselasma rhodostoma) venom.
Archives of biochemistry and biophysics 1994;313(2):373-8.
1993: K S Khoo; W K Kam; Hoon Eng Khoo; Ponnampalam Gopalakrishnakone; Maxey C M Chung
Purification and partial characterization of two cytolysins from a tropical sea anemone, Heteractis magnifica.
Toxicon : official journal of the International Society on Toxinology 1993;31(12):1567-79.
1993: Y M Lim; Maxey C M Chung
Isolation and characterization of pectin methylesterase from papaya.
Archives of biochemistry and biophysics 1993;307(1):15-20.
1993: G Ponnudurai; Maxey C M Chung; Nget-Hong Tan
Isolation and characterization of a hemorrhagin from the venom of Calloselasma rhodostoma (Malayan pit viper).
Toxicon : official journal of the International Society on Toxinology 1993;31(8):997-1005.
1993: M S Yeo; Kandiah Jeyaseelan; Maxey C M Chung; Ponnampalam Gopalakrishnakone; C H Tan; H A Wong
Molecular cloning of a cardiotoxin structural gene from Malayan spitting cobra (Naja naja sputatrix).
Toxicon : official journal of the International Society on Toxinology 1993;31(1):53-60.
1992: C H Poh; R Yuen; Maxey C M Chung; Hoon Eng Khoo
Purification and partial characterization of hyaluronidase from stonefish (Synanceja horrida) venom.
Comparative biochemistry and physiology. B, Comparative biochemistry 1992;101(1-2):159-63.