FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Kristof Chwalisz

Research Profile

Chemicals & Drugs

Anatomy

Disorders

Co-author Network

Publications

TOP 3
Lois Larsen; Karin Coyne; Kristof Chwalisz
Validation of the menstrual pictogram in women with leiomyomata associated with heavy menstrual bleeding.
Shih-Yin Chen; Kristof Chwalisz; Kimberly A Fraser; Mahesh Fuldeore; Luke Boulanger; Steven E Marx
Medical resource use and costs related to central precocious puberty: a retrospective cohort study.
Kristof Chwalisz; Eric Surrey; Frank Z Stanczyk
The hormonal profile of norethindrone acetate: rationale for add-back therapy with gonadotropin-releasing hormone agonists in women with endometriosis.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Kristof Chwalisz (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Lois Larsen; Karin Coyne; Kristof Chwalisz
Validation of the menstrual pictogram in women with leiomyomata associated with heavy menstrual bleeding.
Reproductive sciences (Thousand Oaks, Calif.) 2013;20(6):680-7.
2012: Shih-Yin Chen; Kristof Chwalisz; Kimberly A Fraser; Mahesh Fuldeore; Luke Boulanger; Steven E Marx
Medical resource use and costs related to central precocious puberty: a retrospective cohort study.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2012;18(4):519-28.
2012: Kristof Chwalisz; Eric Surrey; Frank Z Stanczyk
The hormonal profile of norethindrone acetate: rationale for add-back therapy with gonadotropin-releasing hormone agonists in women with endometriosis.
Reproductive sciences (Thousand Oaks, Calif.) 2012;19(6):563-71.
2012: Peter A Lee; Cynthia Mattia-Goldberg; Nelly Mauras; E Kirk Neely; Clifford A Bloch; Karen Klein; Lois Larsen; Kristof Chwalisz
Efficacy and safety of leuprolide acetate 3-month depot 11.25 milligrams or 30 milligrams for the treatment of central precocious puberty.
The Journal of clinical endocrinology and metabolism 2012;97(5):1572-80.
2011: Peter A Lee; Cynthia Mattia-Goldberg; E Kirk Neely; Di Yang; John Fuqua; Lois M Larsen; Kristof Chwalisz
Efficacy of Leuprolide Acetate 1-Month Depot for Central Precocious Puberty (CPP): Growth Outcomes During a Prospective, Longitudinal Study.
International journal of pediatric endocrinology 2011;2011(1):7.
2010: Mahesh J Fuldeore; Steven E. Marx; Kristof Chwalisz; James E Smeeding; Richard A Brook
Add-back therapy use and its impact on LA persistence in patients with endometriosis.
Current medical research and opinion 2010;26(3):729-36.
2010: E Kirk Neely; Peter A Lee; Clifford A Bloch; Lois Larsen; Di Yang; Cynthia Mattia-Goldberg; Kristof Chwalisz
Leuprolide acetate 1-month depot for central precocious puberty: hormonal suppression and recovery.
International journal of pediatric endocrinology 2010;2010():398639.
2009: J Wilkens; Alistair R W Williams; Kristof Chwalisz; C Han; Iain T Cameron; Hilary Critchley
Effect of asoprisnil on uterine proliferation markers and endometrial expression of the tumour suppressor gene, PTEN.
Human reproduction (Oxford, England) 2009;24(5):1036-44.
2008: Julia Wilkens; Kristof Chwalisz; Cong Han; Jane Walker; Iain T Cameron; Susan Ingamells; Alexandra C Lawrence; Mary Ann Lumsden; Dharani K Hapangama; Alistair R W Williams; Hilary Critchley
Effects of the selective progesterone receptor modulator asoprisnil on uterine artery blood flow, ovarian activity, and clinical symptoms in patients with uterine leiomyomata scheduled for hysterectomy.
The Journal of clinical endocrinology and metabolism 2008;93(12):4664-71.
2008: Akira Morikawa; Noriyuki Ohara; Qin Xu; Koji Nakabayashi; Deborah DeManno; Kristof Chwalisz; Shigeki Yoshida; Takeshi Maruo
Selective progesterone receptor modulator asoprisnil down-regulates collagen synthesis in cultured human uterine leiomyoma cells through up-regulating extracellular matrix metalloproteinase inducer.
Human reproduction (Oxford, England) 2008;23(4):944-51.
2007: Noriyuki Ohara; Akira Morikawa; Wei Chen; Jiayin Wang; Deborah DeManno; Kristof Chwalisz; Takeshi Maruo
Comparative effects of SPRM asoprisnil (J867) on proliferation, apoptosis, and the expression of growth factors in cultured uterine leiomyoma cells and normal myometrial cells.
Reproductive sciences (Thousand Oaks, Calif.) 2007;14(8 Suppl):20-7.
2007: Qin Xu; Noriyuki Ohara; Jin Liu; Koji Nakabayashi; Deborah DeManno; Kristof Chwalisz; Shigeki Yoshida; Takeshi Maruo
Selective progesterone receptor modulator asoprisnil induces endoplasmic reticulum stress in cultured human uterine leiomyoma cells.
American journal of physiology. Endocrinology and metabolism 2007;293(4):E1002-11.
2007: Nihar R Nayak; Ov D Slayden; Kunie Mah; Kristof Chwalisz; Robert M Brenner
Antiprogestin-releasing intrauterine devices: a novel approach to endometrial contraception.
Contraception 2007;75(6 Suppl):S104-11.
2007: Kristof Chwalisz; Lois Larsen; Cynthia Mattia-Goldberg; Anthony Edmonds; Walter Elger; Craig A Winkel
A randomized, controlled trial of asoprisnil, a novel selective progesterone receptor modulator, in women with uterine leiomyomata.
Fertility and sterility 2007;87(6):1399-412.
2007: Hiroko Sasaki; Noriyuki Ohara; Qin Xu; Jiayin Wang; Deborah DeManno; Kristof Chwalisz; Shigeki Yoshida; Takeshi Maruo
A novel selective progesterone receptor modulator asoprisnil activates tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated signaling pathway in cultured human uterine leiomyoma cells in the absence of comparable effects on myometrial cells.
The Journal of clinical endocrinology and metabolism 2007;92(2):616-23.
2006: Ov D Slayden; Mary B Zelinski; Kristof Chwalisz; Holger Hess-Stumpp; Robert M Brenner
Chronic progesterone antagonist-estradiol therapy suppresses breakthrough bleeding and endometrial proliferation in a menopausal macaque model.
Human reproduction (Oxford, England) 2006;21(12):3081-90.
2006: Jiayin Wang; Noriyuki Ohara; Zhuo Wang; Wei Chen; Akira Morikawa; Hiroko Sasaki; Deborah DeManno; Kristof Chwalisz; Takeshi Maruo
A novel selective progesterone receptor modulator asoprisnil (J867) down-regulates the expression of EGF, IGF-I, TGFbeta3 and their receptors in cultured uterine leiomyoma cells.
Human reproduction (Oxford, England) 2006;21(7):1869-77.
2006: Wei Chen; Noriyuki Ohara; Jiayin Wang; Qin Xu; Jin Liu; Akira Morikawa; Hiroko Sasaki; Shigeki Yoshida; Deborah DeManno; Kristof Chwalisz; Takeshi Maruo
A novel selective progesterone receptor modulator asoprisnil (J867) inhibits proliferation and induces apoptosis in cultured human uterine leiomyoma cells in the absence of comparable effects on myometrial cells.
The Journal of clinical endocrinology and metabolism 2006;91(4):1296-304.
2006: Kristof Chwalisz; Ramesh Garg; Robert M Brenner; Ov D Slayden; Craig Winkel; Walter Elger
Role of nonhuman primate models in the discovery and clinical development of selective progesterone receptor modulators (SPRMs).
Reproductive biology and endocrinology : RB&E 2006;4 Suppl 1():S8.
2005: Kristof Chwalisz; Maria Claudia Perez; Deborah DeManno; Craig Winkel; Gerd Schubert; Walter Elger
Selective progesterone receptor modulator development and use in the treatment of leiomyomata and endometriosis.
Endocrine reviews 2005;26(3):423-38.
2005: Kristof Chwalisz; Walter Elger; Therese Stickler; Cynthia Mattia-Goldberg; Lois Larsen
The effects of 1-month administration of asoprisnil (J867), a selective progesterone receptor modulator, in healthy premenopausal women.
Human reproduction (Oxford, England) 2005;20(4):1090-9.
2005: Gerd Schubert; Walter Elger; Günter Kaufmann; Birgitt Schneider; Gudrun Reddersen; Kristof Chwalisz
Discovery, chemistry, and reproductive pharmacology of asoprisnil and related 11beta-benzaldoxime substituted selective progesterone receptor modulators (SPRMs).
Seminars in reproductive medicine 2005;23(1):58-73.
2004: Bernard Haendler; Hiroshi Yamanouchi; Bruce A Lessey; Kristof Chwalisz; Holger Hess-Stumpp
Cycle-dependent endometrial expression and hormonal regulation of the fibulin-1 gene.
Molecular reproduction and development 2004;68(3):279-87.
2004: Kristof Chwalisz; Deborah DeManno; Ramesh Garg; Lois Larsen; Cynthia Mattia-Goldberg; Therese Stickler
Therapeutic potential for the selective progesterone receptor modulator asoprisnil in the treatment of leiomyomata.
Seminars in reproductive medicine 2004;22(2):113-9.
2003: Sherri M Borman; Kristof Chwalisz; Richard L Stouffer; Mary B Zelinski-Wooten
Chronic low-dose antiprogestin impairs preimplantation embryogenesis, but not oocyte nuclear maturation or fertilization in rhesus monkeys.
Steroids 2003;68(10-13):1041-51.
2003: Deborah DeManno; Walter Elger; Ramesh Garg; Ronald Lee; Birgitt Schneider; Holger Hess-Stumpp; Gerd Schubert; Kristof Chwalisz
Asoprisnil (J867): a selective progesterone receptor modulator for gynecological therapy.
Steroids 2003;68(10-13):1019-32.
2003: Sherri M Borman; Kristine M Schwinof; C Niemeyer; Kristof Chwalisz; Richard L Stouffer; Mary B Zelinski-Wooten
Low-dose antiprogestin treatment prevents pregnancy in rhesus monkeys and is reversible after 1 year of treatment.
Human reproduction (Oxford, England) 2003;18(1):69-76.
2002: T Thienel; Kristof Chwalisz; Elke Winterhager
Expression of MAPkinases (Erk1/2) during decidualization in the rat: regulation by progesterone and nitric oxide.
Molecular human reproduction 2002;8(5):465-74.
2002: Kristof Chwalisz; Ramesh Garg; Robert M Brenner; Gerd Schubert; Walter Elger
Selective progesterone receptor modulators (SPRMs): a novel therapeutic concept in endometriosis.
Annals of the New York Academy of Sciences 2002;955():373-88; discussion 389-93, 396-406.
2001: Ov D Slayden; Kristof Chwalisz; Robert M Brenner
Reversible suppression of menstruation with progesterone antagonists in rhesus macaques.
Human reproduction (Oxford, England) 2001;16(8):1562-74.
2001: Ov D Slayden; Nihar R Nayak; K A Burton; Kristof Chwalisz; Sharon T Cameron; Hilary Critchley; David T Baird; Robert M Brenner
Progesterone antagonists increase androgen receptor expression in the rhesus macaque and human endometrium.
The Journal of clinical endocrinology and metabolism 2001;86(6):2668-79.
2000: UU Fuhrmann; Holger Hess-Stumpp; A Cleve; G Neef; W Schwede; J Hoffmann; Karl-Heinrich Fritzemeier; Kristof Chwalisz
Synthesis and biological activity of a novel, highly potent progesterone receptor antagonist.
Journal of medicinal chemistry 2000;43(26):5010-6.
2000: Irmgard Classen-Linke; Joachim Alfer; Claudia A Krusche; Kristof Chwalisz; Werner Rath; Henning M Beier
Progestins, progesterone receptor modulators, and progesterone antagonists change VEGF release of endometrial cells in culture.
Steroids 2000;65(10-11):763-71.
2000: Kristof Chwalisz; Robert M Brenner; UU Fuhrmann; Holger Hess-Stumpp; Walter Elger
Antiproliferative effects of progesterone antagonists and progesterone receptor modulators on the endometrium.
Steroids 2000;65(10-11):741-51.
2000: Walter Elger; J Bartley; Birgitt Schneider; G Kaufmann; Gerd Schubert; Kristof Chwalisz
Endocrine pharmacological characterization of progesterone antagonists and progesterone receptor modulators with respect to PR-agonistic and antagonistic activity.
Steroids 2000;65(10-11):713-23.
2000: Nihar R Nayak; Hilary Critchley; Ov D Slayden; A Menrad; Kristof Chwalisz; D T Baird; Robert M Brenner
Progesterone withdrawal up-regulates vascular endothelial growth factor receptor type 2 in the superficial zone stroma of the human and macaque endometrium: potential relevance to menstruation.
The Journal of clinical endocrinology and metabolism 2000;85(9):3442-52.
2000: M Taguchi; Joachim Alfer; Kristof Chwalisz; Henning M Beier; Irmgard Classen-Linke
Endothelial nitric oxide synthase is differently expressed in human endometrial vessels during the menstrual cycle.
Molecular human reproduction 2000;6(2):185-90.
1999: Kristof Chwalisz; Elke Winterhager; T Thienel; RE Garfield
Synergistic role of nitric oxide and progesterone during the establishment of pregnancy in the rat.
Human reproduction (Oxford, England) 1999;14(2):542-52.
1998: Kristof Chwalisz; K Stöckemann; Karl-Heinrich Fritzemeier; UU Fuhrmann
Modulation of oestrogenic effects by progesterone antagonists in the rat uterus.
Human reproduction update 1998;4(5):570-83.
1998: Mary B Zelinski-Wooten; Kristof Chwalisz; S A Iliff; C L Niemeyer; G G Eaton; Donald Lynn (Lynn) Loriaux; Ov D Slayden; Robert M Brenner; Richard L Stouffer
A chronic, low-dose regimen of the antiprogestin ZK 137 316 prevents pregnancy in rhesus monkeys.
Human reproduction (Oxford, England) 1998;13(8):2132-8.
1998: Ov D Slayden; Mary B Zelinski-Wooten; Kristof Chwalisz; Richard L Stouffer; Robert M Brenner
Chronic treatment of cycling rhesus monkeys with low doses of the antiprogestin ZK 137 316: morphometric assessment of the uterus and oviduct.
Human reproduction (Oxford, England) 1998;13(2):269-77.
1998: Mary B Zelinski-Wooten; Ov D Slayden; Kristof Chwalisz; David L Hess; Robert M Brenner; Richard L Stouffer
Chronic treatment of female rhesus monkeys with low doses of the antiprogestin ZK 137 316: establishment of a regimen that permits normal menstrual cyclicity.
Human reproduction (Oxford, England) 1998;13(2):259-67.
1998: Kristof Chwalisz; RE Garfield
Nitric oxide as the final metabolic mediator of cervical ripening.
Human reproduction (Oxford, England) 1998;13(2):245-8.
1997: Kristof Chwalisz; S Shao-Qing; RE Garfield; Henning M Beier
Cervical ripening in guinea-pigs after a local application of nitric oxide.
Human reproduction (Oxford, England) 1997;12(10):2093-101.
1997: Kristof Chwalisz; Robert E Garfield
Regulation of the uterus and cervix during pregnancy and labor. Role of progesterone and nitric oxide.
Annals of the New York Academy of Sciences 1997;828():238-53.
1995: K Stoeckemann; Christa Hegele-Hartung; Kristof Chwalisz
Effects of the progesterone antagonists onapristone (ZK 98 299) and ZK 136 799 on surgically induced endometriosis in intact rats.
Human reproduction (Oxford, England) 1995;10(12):3264-71.
1995: A Nanaev; Kristof Chwalisz; Hans-Georg Frank; Gaby Kohnen; Christa Hegele-Hartung; Peter Kaufmann
Physiological dilation of uteroplacental arteries in the guinea pig depends on nitric oxide synthase activity of extravillous trophoblast.
Cell and tissue research 1995;282(3):407-21.
1995: Kristof Chwalisz; K Stöckemann; UU Fuhrmann; Karl-Heinrich Fritzemeier; A Einspanier; Robert E Garfield
Mechanism of action of antiprogestins in the pregnant uterus.
Annals of the New York Academy of Sciences 1995;761():202-23.
1994: Kristof Chwalisz; M Benson; P Scholz; J Daum; Henning M Beier; Christa Hegele-Hartung
Cervical ripening with the cytokines interleukin 8, interleukin 1 beta and tumour necrosis factor alpha in guinea-pigs.
Human reproduction (Oxford, England) 1994;9(11):2173-81.
1994: Kristof Chwalisz; Robert E Garfield
Antiprogestins in the induction of labor.
Annals of the New York Academy of Sciences 1994;734():387-413.
1992: Christa Hegele-Hartung; Kristof Chwalisz; Henning M Beier
Distribution of estrogen and progesteron receptors in the uterus: an immunohistochemical study in the immature and adult pseudopregnant rabbit.
Histochemistry 1992;97(1):39-50.
1991: Kristof Chwalisz; Falk Fahrenholz; M Hackenberg; R Garfield; W Elger
The progesterone antagonist onapristone increases the effectiveness of oxytocin to produce delivery without changing the myometrial oxytocin receptor concentrations.
American journal of obstetrics and gynecology 1991;165(6 Pt 1):1760-70.
1991: Kristof Chwalisz; Christa Hegele-Hartung; Karl-Heinrich Fritzemeier; Henning M Beier; W Elger
Inhibition of the estradiol-mediated endometrial gland formation by the antigestagen onapristone in rabbits: relationship to uterine estrogen receptors.
Endocrinology 1991;129(1):312-22.
1989: Christa Hegele-Hartung; Kristof Chwalisz; Henning M Beier; W Elger
Ripening of the uterine cervix of the guinea-pig after treatment with the progesterone antagonist onapristone (ZK 98.299): an electron microscopic study.
Human reproduction (Oxford, England) 1989;4(4):369-77.
1989: Christa Hegele-Hartung; Kristof Chwalisz; Henning M Beier; W Elger
[Morphologic aspects of cervix ripening produced by progestin antagonists].
Archives of gynecology and obstetrics 1989;245(1-4):341-3.