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Thomas Ciardelli

Research Profile

Chemicals & Drugs

Phenomena

Physiology

Binding, Competitive

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

Anatomy

Procedures

Living Beings

Mouse

Disorders

Mutagenesis, Insertional

Co-author Network

Publications

TOP 3
Stefano F Liparoto; David G Myszka; Zining Wu; Byron Goldstein; Thomas M Laue; Thomas L Ciardelli
Analysis of the role of the interleukin-2 receptor gamma chain in ligand binding.
EM Fallon; Stefano F Liparoto; K J Lee; Thomas L Ciardelli; Douglas A Lauffenburger
Increased endosomal sorting of ligand to recycling enhances potency of an interleukin-2 analog.
Stefano F Liparoto; Thomas L Ciardelli
Biosensor analysis of the interleukin-2 receptor complex.

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All Publications

2002: Stefano F Liparoto; David G Myszka; Zining Wu; Byron Goldstein; Thomas M Laue; Thomas L Ciardelli
Analysis of the role of the interleukin-2 receptor gamma chain in ligand binding.
Biochemistry 2002;41(8):2543-51.
2000: EM Fallon; Stefano F Liparoto; K J Lee; Thomas L Ciardelli; Douglas A Lauffenburger
Increased endosomal sorting of ligand to recycling enhances potency of an interleukin-2 analog.
The Journal of biological chemistry 2000;275(10):6790-7.
1999: Stefano F Liparoto; Thomas L Ciardelli
Biosensor analysis of the interleukin-2 receptor complex.
Journal of molecular recognition : JMR 1999;12(5):316-21.
1999: Zining Wu; B Goldstein; Thomas M Laue; Stefano F Liparoto; M J Nemeth; Thomas L Ciardelli
Solution assembly of the pseudo-high affinity and intermediate affinity interleukin-2 receptor complexes.
Protein science : a publication of the Protein Society 1999;8(3):482-9.
1997: B L Lee; Thomas L Ciardelli
Structural modifications of interleukin-2 at positions 47 and 65.
Biochemical and biophysical research communications 1997;233(2):309-15.
1997: P J Buchli; Zining Wu; Thomas L Ciardelli
The functional display of interleukin-2 on filamentous phage.
Archives of biochemistry and biophysics 1997;339(1):79-84.
1996: D Z Chang; Z Wu; Thomas L Ciardelli
A point mutation in interleukin-2 that alters ligand internalization.
The Journal of biological chemistry 1996;271(23):13349-55.
1995: Z Wu; K W Johnson; Y Choi; Thomas L Ciardelli
Ligand binding analysis of soluble interleukin-2 receptor complexes by surface plasmon resonance.
The Journal of biological chemistry 1995;270(27):16045-51.
1995: Z Wu; K W Johnson; B Goldstein; Y Choi; S F Eaton; Thomas M Laue; Thomas L Ciardelli
Solution assembly of a soluble, heteromeric, high affinity interleukin-2 receptor complex.
The Journal of biological chemistry 1995;270(27):16039-44.
1995: Z Wu; K W Johnson; Thomas L Ciardelli
Ligand binding analysis of interleukin-2 receptor complexes using surface plasmon resonance.
Journal of immunological methods 1995;183(1):127-30.
1995: D Z Chang; M L Tasayco; Thomas L Ciardelli
Structural analogs of interleukin-2: a point mutation that facilitates biological response.
Molecular pharmacology 1995;47(1):206-11.
1994: Z Wu; S F Eaton; Thomas M Laue; K W Johnson; T R Sana; Thomas L Ciardelli
Coiled-coil molecular recognition: directed solution assembly of receptor ectodomains.
Protein engineering 1994;7(9):1137-44.
1994: W G Berndt; D Z Chang; Kendall A Smith; Thomas L Ciardelli
Mutagenic analysis of a receptor contact site on interleukin-2: preparation of an IL-2 analog with increased potency.
Biochemistry 1994;33(21):6571-7.
1994: T R Sana; Z Wu; Kendall A Smith; Thomas L Ciardelli
Expression and ligand binding characterization of the beta-subunit (p75) ectodomain of the interleukin-2 receptor.
Biochemistry 1994;33(19):5838-45.
1993: P Buchli; Thomas L Ciardelli
Structural and biologic properties of a human aspartic acid-126 interleukin-2 analog.
Archives of biochemistry and biophysics 1993;307(2):411-5.
1993: C L Chan; Z Wu; Thomas L Ciardelli; Alan Eastman; E Bresnick
Kinetic and DNA-binding properties of recombinant human O6-methylguanine-DNA methyltransferase.
Archives of biochemistry and biophysics 1993;300(1):193-200.
1992: B E Landgraf; B Goldstein; D P Williams; J R Murphy; T R Sana; Kendall A Smith; Thomas L Ciardelli
Recombinant interleukin-2 analogs. Dynamic probes for receptor structure.
The Journal of biological chemistry 1992;267(26):18511-9.
1992: B Lee; Thomas L Ciardelli
Clinical applications of cytokines for immunostimulation and immunosuppression.
Progress in drug research. Fortschritte der Arzneimittelforschung. Progrès des recherches pharmaceutiques 1992;39():167-96.
1991: C E Ackland; W G Berndt; J E Frezza; B E Landgraf; K W Pritchard; Thomas L Ciardelli
Monitoring of protein conformation by high-performance size-exclusion liquid chromatography and scanning diode array second-derivative UV absorption spectroscopy.
Journal of chromatography 1991;540(1-2):187-98.
1991: S F Gonsalves; B E Landgraf; Thomas L Ciardelli; H L Borison
Early toxicity of recombinant interleukin-2 in cats.
Archives internationales de pharmacodynamie et de thérapie 1991;310():175-85.
1991: B E Landgraf; D P Williams; J R Murphy; Kendall A Smith; Thomas L Ciardelli
Conformational perturbation of interleukin-2: a strategy for the design of cytokine analogs.
Proteins 1991;9(3):207-16.
1989: B Landgraf; Fred Cohen; Kendall A Smith; Robert A Gadski; Thomas L Ciardelli
Structural significance of the C-terminal amphiphilic helix of interleukin-2.
The Journal of biological chemistry 1989;264(2):816-22.
1988: L I Smith; Jack E Bodwell; D B Mendel; Thomas L Ciardelli; W G North; A Munck
Identification of cysteine-644 as the covalent site of attachment of dexamethasone 21-mesylate to murine glucocorticoid receptors in WEHI-7 cells.
Biochemistry 1988;27(10):3747-53.
1988: Thomas L Ciardelli; B Landgraf; Robert A Gadski; J Strnad; Fred Cohen; Kendall A Smith
A design approach to the structural analysis of interleukin-2.
Journal of molecular recognition : JMR 1988;1(1):42-7.