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G Ciarrocchi

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Anatomy

Hela Cells

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Living Beings

Physiology

Phenomena

Ultraviolet Rays

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Co-Publications
Name
29
Montecucco, Alessandra
25
Spadari, Silvio
16
Focher, Federico
8
Biamonti, Giuseppe
5
Rossi, R
3
Arcamone, FM
2
maga, giovanni
2
Palumbo, Manlio
2
Capolongo, L
2
Chevallier-Lagente, O
2
Manservigi, Roberto
2
Mondello, Chiara
1
Motycka, Teresa
1
Negri, Claudia
1
Palù, Giorgio

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Publications

TOP 3
Ciarrocchi G; MacPhee D G; Deady L W; Tilley L
Specific inhibition of the eubacterial DNA ligase by arylamino compounds.
Rossi R; Villa A; Negri C; Scovassi I; Ciarrocchi G; Biamonti G; Montecucco A
The replication factory targeting sequence/PCNA-binding site is required in G(1) to control the phosphorylation status of DNA ligase I.
Montecucco A; Rossi R; Levin D S; Gary R; Park M S; Motycka T A; Ciarrocchi G; Villa A; Biamonti G; Tomkinson A E
DNA ligase I is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: identification of a common targeting mechanism for the assembly of replication factories.

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All Publications

1999: Ciarrocchi G; MacPhee D G; Deady L W; Tilley L
Specific inhibition of the eubacterial DNA ligase by arylamino compounds.
Antimicrobial agents and chemotherapy 1999;43(11):2766-72.
1999: Rossi R; Villa A; Negri C; Scovassi I; Ciarrocchi G; Biamonti G; Montecucco A
The replication factory targeting sequence/PCNA-binding site is required in G(1) to control the phosphorylation status of DNA ligase I.
The EMBO journal 1999;18(20):5745-54.
1998: Montecucco A; Rossi R; Levin D S; Gary R; Park M S; Motycka T A; Ciarrocchi G; Villa A; Biamonti G; Tomkinson A E
DNA ligase I is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: identification of a common targeting mechanism for the assembly of replication factories.
The EMBO journal 1998;17(13):3786-95.
1997: Rossi R; Montecucco A; Ciarrocchi G; Biamonti G
Functional characterization of the T4 DNA ligase: a new insight into the mechanism of action.
Nucleic acids research 1997;25(11):2106-13.
1996: Rossi R; Montecucco A; Capolongo L; Mezzina M; Chevallier-Lagente O; Sarasin A; Ciarrocchi G
The alkylating antitumor drug tallimustine does not induce DNA repair.
Anticancer research 1996;16(6B):3779-83.
1995: Gallina A; Rossi F; Milanesi G; Rossi R; Montecucco A; Ciarrocchi G
Characterization of human DNA ligase I expressed in a baculovirus-insect cell system.
The Biochemical journal 1995;312 ( Pt 2)():593-7.
1995: Montecucco A; Savini E; Weighardt F; Rossi R; Ciarrocchi G; Villa A; Biamonti G
The N-terminal domain of human DNA ligase I contains the nuclear localization signal and directs the enzyme to sites of DNA replication.
The EMBO journal 1995;14(21):5379-86.
1995: Spadari S; Ciarrocchi G; Focher F; Verri A; Maga G; Arcamone F; Iafrate E; Manzini S; Garbesi A; Tondelli L
5-Iodo-2'-deoxy-L-uridine and (E)-5-(2-bromovinyl)-2'-deoxy-L-uridine: selective phosphorylation by herpes simplex virus type 1 thymidine kinase, antiherpetic activity, and cytotoxicity studies.
Molecular pharmacology 1995;47(6):1231-8.
1995: Montecucco A; Savini E; Biamonti G; Stefanini M; Focher F; Ciarrocchi G
Late induction of human DNA ligase I after UV-C irradiation.
Nucleic acids research 1995;23(6):962-6.
1995: Eveno E; Quilliet X; Chevallier-Lagente O; Daya-Grosjean L; Stary A; Zeng L; Benoit A; Savini E; Ciarrocchi G; Kannouche P
Stable SV40-transformation and characterisation of some DNA repair properties of fibroblasts from a trichothiodystrophy patient.
Biochimie 1995;77(11):906-12.
1994: Savini E; Biamonti G; Ciarrocchi G; Montecucco A
Cloning and sequence analysis of a cDNA coding for the murine DNA ligase I enzyme.
Gene 1994;144(2):253-7.
1994: Montecucco A; Capolongo L; Melegaro G; Mondello C; Ciarrocchi G
Temperature influences both cytotoxicity and DNA nicking efficiency of the antitumor distamycin analogue FCE24517.
Anticancer research 1994;14(1A):189-92.
1993: Ciarrocchi G; Lestingi M; Wright G; Montecucco A
Bacteriophage T4 and human type I DNA ligases relax DNA under joining conditions.
Nucleic acids research 1993;21(25):5934-9.
1993: Montecucco A; Lestingi M; Rossignol J M; Elder R H; Ciarrocchi G
Lack of discrimination between DNA ligases I and III by two classes of inhibitors, anthracyclines and distamycins.
Biochemical pharmacology 1993;45(7):1536-9.
1992: Montecucco A; Biamonti G; Savini E; Focher F; Spadari S; Ciarrocchi G
DNA ligase I gene expression during differentiation and cell proliferation.
Nucleic acids research 1992;20(23):6209-14.
1992: Palù G; Valisena S; Ciarrocchi G; Gatto B; Palumbo M
Quinolone binding to DNA is mediated by magnesium ions.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(20):9671-5.
1992: Spadari S; Maga G; Focher F; Ciarrocchi G; Manservigi R; Arcamone F; Capobianco M; Carcuro A; Colonna F; Iotti S
L-thymidine is phosphorylated by herpes simplex virus type 1 thymidine kinase and inhibits viral growth.
Journal of medicinal chemistry 1992;35(22):4214-20.
1992: Fontana M; Lestingi M; Mondello C; Braghetti A; Montecucco A; Ciarrocchi G
DNA binding properties of FCE24517, an electrophilic distamycin analogue.
Anti-cancer drug design 1992;7(2):131-41.
1992: Elder R H; Montecucco A; Ciarrocchi G; Rossignol J M
Rat liver DNA ligases. Catalytic properties of a novel form of DNA ligase.
European journal of biochemistry / FEBS 1992;203(1-2):53-8.
1991: Montecucco A; Biamonti G; Ciarrocchi G
A new sequence variant of the human DNA ligase type I gene (LIG I).
Nucleic acids research 1991;19(22):6347.
1991: Ciarrocchi G; Lestingi M; Fontana M; Spadari S; Montecucco A
Correlation between anthracycline structure and human DNA ligase inhibition.
The Biochemical journal 1991;279 ( Pt 1)():141-6.
1991: Ciarrocchi G; Fontana M; Spadari S; Montecucco A
Inhibition of human DNA ligase by anthracyclines and distamycins.
Anticancer research 1991;11(3):1317-22.
1991: Montecucco A; Fontana M; Focher F; Lestingi M; Spadari S; Ciarrocchi G
Specific inhibition of human DNA ligase adenylation by a distamycin derivative possessing antitumor activity.
Nucleic acids research 1991;19(5):1067-72.
1990: Montecucco A; Lestingi M; Pedrali-Noy G; Spadari S; Ciarrocchi G
Use of ATP, dATP and their alpha-thio derivatives to study DNA ligase adenylation.
The Biochemical journal 1990;271(1):265-8.
1990: Parolin C; Montecucco A; Ciarrocchi G; Pedrali-Noy G; Valisena S; Palumbo M; Palu G
The effect of the minor groove binding agent DAPI (4,6-diamidino-2-phenyl-indole) on DNA-directed enzymes: an attempt to explain inhibition of plasmid expression in Escherichia coli [corrected]
FEMS microbiology letters 1990;56(3):341-6.
1990: Montecucco A; Pedrali-Noy G; Spadari S; Lestingi M; Ciarrocchi G
Effects of DNA-binding drugs on T4 DNA ligase.
The Biochemical journal 1990;266(2):379-84.
1990: Hildebrand C; Sandoli D; Focher F; Gambino J; Ciarrocchi G; Spadari S; Wright G
Structure-activity relationships of N2-substituted guanines as inhibitors of HSV1 and HSV2 thymidine kinases.
Journal of medicinal chemistry 1990;33(1):203-6.
1989: Focher F; Sandoli D; Hildebrand C; Sangalli S; Ciarrocchi G; Rebuzzini A; Pedrali-Noy G; Manservigi R; Wright G; Brown N
Nucleoside analogs as non-substrate inhibitors of herpes simplex viruses thymidine kinase.
Methods and findings in experimental and clinical pharmacology 1989;11(9):577-82.
1989: Montecucco A; Pedrali-Noy G; Spadari S; Zanolin E; Chiesa M T; Ciarrocchi G
DNA ligases are specifically inhibited by anthracyclines with a free 3'-amino group.
Journal of chemotherapy (Florence, Italy) 1989;1(4 Suppl):1138-9.
1989: Focher F; Sandoli D; Wright G; Sangalli S; Ciarrocchi G; Pedrali-Noy G; Rebuzzini A; Brown N; Spadari S
A novel pharmacological approach to herpes virus infections.
Journal of chemotherapy (Florence, Italy) 1989;1(4 Suppl):1107-8.
1989: Spadari S; Montecucco A; Pedrali-Noy G; Ciarrocchi G; Focher F; Hübscher U
A double-loop model for the replication of eukaryotic DNA.
Mutation research 1989;219(3):147-56.
1988: Montecucco A; Pedrali-Noy G; Spadari S; Ciarrocchi G
Multiple roles of DNA ligase at the replication fork.
Biochimica et biophysica acta 1988;951(2-3):330-4.
1988: Montecucco A; Ciarrocchi G
AMP-dependent DNA relaxation catalyzed by DNA ligase occurs by a nicking-closing mechanism.
Nucleic acids research 1988;16(15):7369-81.
1988: Focher F; Hildebrand C; Freese S; Ciarrocchi G; Noonan T; Sangalli S; Brown N; Spadari S; Wright G
N2-phenyldeoxyguanosine: a novel selective inhibitor of herpes simplex thymidine kinase.
Journal of medicinal chemistry 1988;31(8):1496-500.
1988: Montecucco A; Pedrali-Noy G; Spadari S; Zanolin E; Ciarrocchi G
DNA unwinding and inhibition of T4 DNA ligase by anthracyclines.
Nucleic acids research 1988;16(9):3907-18.
1988: Montecucco A; Spadari S; Focher F; Pedrali-Noy G; Sala C; Palù G; Ciarrocchi G
Detection of the effects of intercalating and non-intercalating drugs on DNA structure.
Biochemical pharmacology 1988;37(9):1853-4.
1988: Focher F; Sangalli S; Ciarrocchi G; Della Valle G; Talarico D; Rebuzzini A; Wright G; Brown N; Spadari S
N2-substituted guanine derivatives act as selective non substrate inhibitors of HSV I thymidine kinase.
Biochemical pharmacology 1988;37(9):1877-8.
1988: Ciarrocchi G; Montecucco A; Pedrali-Noy G; Spadari S
A novel target in DNA metabolism for cytotoxic drugs.
Biochemical pharmacology 1988;37(9):1803-4.
1987: Spadari S; Sutherland B M; Pedrali-Noy G; Focher F; Chiesa M T; Ciarrocchi G
Alteration of DNA tertiary structure by physical and chemical carcinogens: involvement in DNA repair processes.
Toxicologic pathology 1987;15(1):82-7.
1986: Sutherland B M; Ciarrocchi G; Ciomei M; Sutherland J C
Quantitation of DNA damage in non-radioactive DNA.
Photochemistry and photobiology 1986;44(3):391-6.
1986: Spadari S; Pedrali-Noy G; Focher F; Montecucco A; Bordoni T; Geroni C; Giuliani F C; Ventrella G; Arcamone F; Ciarrocchi G
DNA polymerases and DNA topoisomerases as targets for the development of anticancer drugs.
Anticancer research 1986;6(5):935-40.
1986: Sutherland B M; Oliveira O M; Ciarrocchi G; Brash D E; Haseltine W A; Lewis R J; Hanawalt P C
Substrate range of the 40,000-dalton DNA-photoreactivating enzyme from Escherichia coli.
Biochemistry 1986;25(3):681-7.
1985: Ciarrocchi G; Sutherland B M; Sutherland J C
Incandescent lamps can produce pyrimidine dimers in DNA.
Photochemistry and photobiology 1985;41(6):703-5.
1985: Spadari S; Focher F; Kuenzle C; Corey E J; Myers A G; Hardt N; Rebuzzini A; Ciarrocchi G; Pedrali-Noy G
In vivo distribution and activity of aphidicolin on dividing and quiescent cells.
Antiviral research 1985;5(2):93-101.
1985: Spadari S; Focher F; Sala F; Ciarrocchi G; Koch G; Falaschi A; Pedrali-Noy G
Control of cell division by aphidicolin without adverse effects upon resting cells.
Arzneimittel-Forschung 1985;35(7):1108-16.
1984: Ciomei M; Sutherland B M; Ciarrocchi G
Quantification of pyrimidine dimers and apurinic sites in DNAs of uniform length.
Photochemistry and photobiology 1984;39(5):593-6.
1984: Ciomei M; Spadari S; Pedrali-Noy G; Ciarrocchi G
Structural alterations of pathologically or physiologically modified DNA.
Nucleic acids research 1984;12(4):1977-89.
1984: Spadari S; Pedrali-Noy G; Falaschi M C; Ciarrocchi G
Control of DNA replication and cell proliferation in eukaryotes by aphidicolin.
Toxicologic pathology 1984;12(2):143-8.
1984: Spadari S; Pedrali-Noy G; Ciomei M; Rebuzzini A; Hübscher U; Ciarrocchi G
DNA methylation and DNA structure.
Advances in experimental medicine and biology 1984;179():551-6.
1983: Ciarrocchi G; Sutherland B M
Irradiation of circular DNA with 254 nm radiation or sensitization in the presence of Ag+: evidence for unwinding by photoproducts other than pyrimidine dimers.
Photochemistry and photobiology 1983;38(3):259-63.
1983: Pedrini A M; Ciarrocchi G
Inhibition of Micrococcus luteus DNA topoisomerase I by UV photoproducts.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(7):1787-91.
1982: Ciarrocchi G; Sutherland B M; Pedrini A M
Photoreversal of DNA unwinding caused by pyrimidine dimers.
Biochimie 1982;64(8-9):665-8.
1982: Ciarrocchi G; Pedrini A M
Determination of pyrimidine dimer unwinding angle by measurement of DNA electrophoretic mobility.
Journal of molecular biology 1982;155(2):177-83.
1980: Cobianchi F; Attolini C; Falaschi A; Ciarrocchi G
Bacillus subtilis deoxyribonuclease activity specific for single-stranded deoxyribonucleic acid: cellular site and variations during germination and sporulation.
Journal of bacteriology 1980;141(2):968-70.

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