FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Giuseppe Ciccotosto

Research Profile

Living Beings

Chemicals & Drugs

Anatomy

Disorders

Alzheimer's Disease

Concepts & Ideas

Co-author Network

Publications

TOP 3
Vijaya Kenche; Jeffrey Kwok; Varsha Lal; Colin L Masters; Kazuma Murakami; Keyla Perez; Nikki Sherratt; Irene Volitakes; Roberto Cappai; Giuseppe D Ciccotosto; Mikhalina Cortes; Nicole Critch; Lin W Hung; Paul A Adlard; Kevin J Barnham
Development of a platinum complex as an anti-amyloid agent for the therapy of Alzheimer's disease.
Giuseppe D Ciccotosto; James W M Chon; Timothy T Y Chow; Noga Kozer; Andrew H A Clayton
Aggregation distributions on cells determined by photobleaching image correlation spectroscopy.
Jiang-Li Tan; Anthony Robert White; Qiao-Xin Li; Giuseppe D Ciccotosto; Peter J Crouch; Janetta G Culvenor; Geneviève Evin
Mild Oxidative Stress Induces Redistribution of BACE1 in Non-Apoptotic Conditions and Promotes the Amyloidogenic Processing of Alzheimer's Disease Amyloid Precursor Protein.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Giuseppe Ciccotosto (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Vijaya Kenche; Jeffrey Kwok; Varsha Lal; Colin L Masters; Kazuma Murakami; Keyla Perez; Nikki Sherratt; Irene Volitakes; Roberto Cappai; Giuseppe D Ciccotosto; Mikhalina Cortes; Nicole Critch; Lin W Hung; Paul A Adlard; Kevin J Barnham
Development of a platinum complex as an anti-amyloid agent for the therapy of Alzheimer's disease.
Angewandte Chemie (International ed. in English) 2013;52(12):3374-8.
2013: Giuseppe D Ciccotosto; James W M Chon; Timothy T Y Chow; Noga Kozer; Andrew H A Clayton
Aggregation distributions on cells determined by photobleaching image correlation spectroscopy.
Biophysical journal 2013;104(5):1056-64.
2013: Jiang-Li Tan; Anthony Robert White; Qiao-Xin Li; Giuseppe D Ciccotosto; Peter J Crouch; Janetta G Culvenor; Geneviève Evin
Mild Oxidative Stress Induces Redistribution of BACE1 in Non-Apoptotic Conditions and Promotes the Amyloidogenic Processing of Alzheimer's Disease Amyloid Precursor Protein.
PloS one 2013;8(4):e61246.
2012: Peng Lei; Catriona A McLean; Blaine R Roberts; Loredana Spoerri; Irene Volitakis; Bruce X W Wong; David K Wright; Roberto Cappai; Robert A Cherny; Giuseppe D Ciccotosto; James A Duce; Gary F Egan; David I Finkelstein; Linh Q Lam; Paul A Adlard; Scott Ayton; Ashley I Bush
Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export.
Nature medicine 2012;18(2):291-5.
2012: Tracy Ho; Frédéric Mascarelli; Kirstan A Vessey; Roberto Cappai; Giuseppe D Ciccotosto; Virginie Dinet; Erica L Fletcher
Amyloid precursor protein is required for normal function of the rod and cone pathways in the mouse retina.
PloS one 2012;7(1):e29892.
2011: Victoria A Lawson; Colin L Masters; Jeremy M Welton; Roberto Cappai; Peter J Crouch; Helen M Klemm; Giuseppe D Ciccotosto
Gene knockout of tau expression does not contribute to the pathogenesis of prion disease.
Journal of neuropathology and experimental neurology 2011;70(11):1036-45.
2011: Joanne M Caine; Giuseppe D Ciccotosto; Sonia E Sankovich; Victor A Streltsov; Prashant R Bharadwaj; Jose Varghese
Oligomerization and toxicity of Aβ fusion proteins.
Biochemical and biophysical research communications 2011;409(3):477-82.
2011: Virginie Dinet; Na An; Giuseppe D Ciccotosto; Julien Bruban; Agathe Maoui; Shayne A Bellingham; Andrew F Hill; Olav M Andersen; Anders Nykjaer; Laurent Jonet; Roberto Cappai; Frédéric Mascarelli
APP involvement in retinogenesis of mice.
Acta neuropathologica 2011;121(3):351-63.
2011: Giuseppe D Ciccotosto; Deborah J Tew; Simon C Drew; Danielle G Smith; Timothy Johanssen; Varsha Lal; Tong-Lay Crystal Lau; Keyla Perez; Cyril C Curtain; John D Wade; Frances Separovic; Colin L Masters; Jeffrey P Smith; Kevin J Barnham; Roberto Cappai
Stereospecific interactions are necessary for Alzheimer disease amyloid-β toxicity.
Neurobiology of aging 2011;32(2):235-48.
2010: James A Duce; Andrew Tsatsanis; Michael A Cater; Simon A James; Elysia Robb; Krutika Wikhe; Su Ling Leong; Keyla Perez; Timothy Johanssen; Mark A Greenough; Hyun-Hee Cho; Denise Galatis; Robert D. Moir; Colin L Masters; Catriona McLean; Rudolph E Tanzi; Roberto Cappai; Kevin J Barnham; Giuseppe D Ciccotosto; Jack T Rogers; Ashley I Bush
Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease.
Cell 2010;142(6):857-67.
2010: Victoria M Perreau; Sandra Orchard; Paul A Adlard; Shayne A Bellingham; Roberto Cappai; Giuseppe D Ciccotosto; Tiffany F Cowie; Peter J Crouch; James A Duce; Geneviève Evin; Noel G Faux; Andrew Hill; Ya Hui Hung; Simon A James; Qiao-Xin Li; Su San Mok; Deborah J Tew; Anthony R White; Ashley I Bush; Henning Hermjakob; Colin L Masters
A domain level interaction network of amyloid precursor protein and Abeta of Alzheimer's disease.
Proteomics 2010;10(12):2377-95.
2010: K N Harikrishnan; Richard Bayles; Giuseppe D Ciccotosto; Scott Maxwell; Roberto Cappai; Gregory J Pelka; Patrick P L Tam; John Christodoulou; Assam El-Osta
Alleviating transcriptional inhibition of the norepinephrine slc6a2 transporter gene in depolarized neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(4):1494-501.
2010: Danielle G Smith; Giuseppe D Ciccotosto; Deborah J Tew; Keyla Perez; Cyril C Curtain; John F Boas; Colin L Masters; Roberto Cappai; Kevin J Barnham
Histidine 14 modulates membrane binding and neurotoxicity of the Alzheimer's disease amyloid-beta peptide.
Journal of Alzheimer's disease : JAD 2010;19(4):1387-400.
2009: Efrat Abramov; Iftach Dolev; Hilla Fogel; Giuseppe D Ciccotosto; Eyal Ruff; Inna Slutsky
Amyloid-beta as a positive endogenous regulator of release probability at hippocampal synapses.
Nature neuroscience 2009;12(12):1567-76.
2009: Jeffrey P Smith; Varsha Lal; David Bowser; Roberto Cappai; Colin L Masters; Giuseppe D Ciccotosto
Stimulus pattern dependence of the Alzheimer's disease amyloid-beta 42 peptide's inhibition of long term potentiation in mouse hippocampal slices.
Brain research 2009;1269():176-84.
2008: Lin Wai Hung; Giuseppe D Ciccotosto; Eleni Giannakis; Deborah J Tew; Keyla Perez; Colin L Masters; Roberto Cappai; John D Wade; Kevin J Barnham
Amyloid-beta peptide (Abeta) neurotoxicity is modulated by the rate of peptide aggregation: Abeta dimers and trimers correlate with neurotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(46):11950-8.
2008: Kevin J Barnham; Vijaya Kenche; Giuseppe D Ciccotosto; David P Smith; Deborah J Tew; Xiang Liu; Keyla Perez; Greg A Cranston; Timothy J Johanssen; Irene Volitakis; Ashley I Bush; Colin L Masters; Anthony R White; Jeffrey P Smith; Robert A Cherny; Roberto Cappai
Platinum-based inhibitors of amyloid-beta as therapeutic agents for Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(19):6813-8.
2008: Deborah J Tew; Stephen P Bottomley; David P Smith; Giuseppe D Ciccotosto; jeffrey babon; Mark G Hinds; Colin L Masters; Roberto Cappai; Kevin J Barnham
Stabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptide.
Biophysical journal 2008;94(7):2752-66.
2008: Giuseppe D Ciccotosto; Roberto Cappai; Anthony R White
Neurotoxicity of prion peptides on cultured cerebellar neurons.
Methods in molecular biology (Clifton, N.J.) 2008;459():83-96.
2008: Tai Du; Giuseppe D Ciccotosto; Greg A Cranston; Gulcan Kocak; Colin L Masters; Peter J Crouch; Roberto Cappai; Anthony R White
Neurotoxicity from glutathione depletion is mediated by Cu-dependent p53 activation.
Free radical biology & medicine 2008;44(1):44-55.
2007: Mithu De; Giuseppe D Ciccotosto; Richard E Mains; Betty A Eipper
Trafficking of a secretory granule membrane protein is sensitive to copper.
The Journal of biological chemistry 2007;282(32):23362-71.
2007: David P Smith; Giuseppe D Ciccotosto; Deborah J Tew; Michelle T Fodero-Tavoletti; Timothy Johanssen; Colin L Masters; Kevin J Barnham; Roberto Cappai
Concentration dependent Cu2+ induced aggregation and dityrosine formation of the Alzheimer's disease amyloid-beta peptide.
Biochemistry 2007;46(10):2881-91.
2006: David P Smith; Danielle G Smith; Cyril C Curtain; John F Boas; John R Pilbrow; Giuseppe D Ciccotosto; Tong-Lay Crystal Lau; Deborah J Tew; Keyla Perez; John D Wade; Ashley I Bush; Simon C Drew; Frances Separovic; Colin L Masters; Roberto Cappai; Kevin J Barnham
Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge.
The Journal of biological chemistry 2006;281(22):15145-54.
2006: Marcus Brazier; Victoria Lewis; Giuseppe D Ciccotosto; Genevieve M Klug; Victoria A Lawson; Roberto Cappai; James W Ironside; Colin L Masters; Andrew Hill; Anthony R White; Steven Collins
Correlative studies support lipid peroxidation is linked to PrP(res) propagation as an early primary pathogenic event in prion disease.
Brain research bulletin 2006;68(5):346-54.
2005: Roberto Cappai; Fang Cheng; Giuseppe D Ciccotosto; B Elise Needham; Colin L Masters; Gerd Multhaup; Lars-Ake Fransson; Katrin Mani
The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo.
The Journal of biological chemistry 2005;280(14):13913-20.
2005: Anna K Tickler; Danielle G Smith; Giuseppe D Ciccotosto; Deborah J Tew; Cyril C Curtain; Darryl Carrington; Colin L Masters; Ashley I Bush; Robert A Cherny; Roberto Cappai; John D Wade; Kevin J Barnham
Methylation of the imidazole side chains of the Alzheimer disease amyloid-beta peptide results in abolition of superoxide dismutase-like structures and inhibition of neurotoxicity.
The Journal of biological chemistry 2005;280(14):13355-63.
2005: Peter J Crouch; Rachel Blake; James A Duce; Giuseppe D Ciccotosto; Qiao-Xin Li; Kevin J Barnham; Cyril C Curtain; Robert A Cherny; Roberto Cappai; Thomas Dyrks; Colin L Masters; Ian A Trounce
Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(3):672-9.
2004: Giuseppe D Ciccotosto; Deborah J Tew; Cyril C Curtain; Danielle Smith; Darryl Carrington; Colin L Masters; Ashley I Bush; Robert A Cherny; Roberto Cappai; Kevin J Barnham
Enhanced toxicity and cellular binding of a modified amyloid beta peptide with a methionine to valine substitution.
The Journal of biological chemistry 2004;279(41):42528-34.
2004: Shayne A Bellingham; Giuseppe D Ciccotosto; B Elise Needham; Lisa R Fodero; Anthony R White; Colin L Masters; Roberto Cappai; James Camakaris
Gene knockout of amyloid precursor protein and amyloid precursor-like protein-2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts.
Journal of neurochemistry 2004;91(2):423-8.
2004: Kevin J Barnham; Fredrik Haeffner; Giuseppe D Ciccotosto; Cyril C Curtain; Deborah J Tew; Christine Mavros; Konrad Beyreuther; Darryl Carrington; Colin L Masters; Robert A Cherny; Roberto Cappai; Ashley I Bush
Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(12):1427-9.
2003: Kevin J Barnham; Giuseppe D Ciccotosto; Anna K Tickler; Feda E Ali; Danielle G Smith; Nicholas A Williamson; Yuen-Han Lam; Darryl Carrington; Deborah J Tew; Gulcan Kocak; Irene Volitakis; Frances Separovic; Colin J Barrow; John D Wade; Colin L Masters; Robert A Cherny; Cyril C Curtain; Ashley I Bush; Roberto Cappai
Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation.
The Journal of biological chemistry 2003;278(44):42959-65.
2003: Tami Steveson; Giuseppe D Ciccotosto; Xin-Ming Ma; Gregory P Mueller; Richard E Mains; Betty A Eipper
Menkes protein contributes to the function of peptidylglycine alpha-amidating monooxygenase.
Endocrinology 2003;144(1):188-200.
2000: Giuseppe D Ciccotosto; Tracey Hand; Richard E Mains; Betty A Eipper
Breeding stock-specific variation in peptidylglycine alpha-amidating monooxygenase messenger ribonucleic acid splicing in rat pituitary.
Endocrinology 2000;141(2):476-86.
1999: Giuseppe D Ciccotosto; M R Schiller; Betty A Eipper; Richard E Mains
Induction of integral membrane PAM expression in AtT-20 cells alters the storage and trafficking of POMC and PC1.
The Journal of cell biology 1999;144(3):459-71.