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Klaus Cichutek

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Lindsay Elmgren; Elwyn Griffiths; Teeranart Jivapaisarnpong; Atsushi Kato; Xuguang Li; Philip Minor; Michael Pfleiderer; Yeowon Sohn; James Southern; Junzhi Wang; Carolyn Wilson; Robert Ball; Marco Cavaleri; Klaus Cichutek; David Wood
A global regulatory science agenda for vaccines.
Katrin Friedrich; Jan Rh Hanauer; Kay-Martin Hanschmann; Christian Jost; Christian J Buchholz; Roberto Cattaneo; Klaus Cichutek; Christodoulos Filippis; Robert C Münch; Kah-Whye Peng; Andreas Plückthun; Steffen Prüfer; Iris Völker; Michael Mühlebach
DARPin-targeting of measles virus: unique bispecificity, effective oncolysis, and enhanced safety.
Barbara Langer; Matthias Renner; Jürgen Scherer; Silke Schüle; Klaus Cichutek
Safety assessment of biolistic DNA vaccination.

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2013: Lindsay Elmgren; Elwyn Griffiths; Teeranart Jivapaisarnpong; Atsushi Kato; Xuguang Li; Philip Minor; Michael Pfleiderer; Yeowon Sohn; James Southern; Junzhi Wang; Carolyn Wilson; Robert Ball; Marco Cavaleri; Klaus Cichutek; David Wood
A global regulatory science agenda for vaccines.
Vaccine 2013;31 Suppl 2():B163-75.
2013: Katrin Friedrich; Jan Rh Hanauer; Kay-Martin Hanschmann; Christian Jost; Christian J Buchholz; Roberto Cattaneo; Klaus Cichutek; Christodoulos Filippis; Robert C Münch; Kah-Whye Peng; Andreas Plückthun; Steffen Prüfer; Iris Völker; Michael Mühlebach
DARPin-targeting of measles virus: unique bispecificity, effective oncolysis, and enhanced safety.
Molecular therapy : the journal of the American Society of Gene Therapy 2013;21(4):849-59.
2013: Barbara Langer; Matthias Renner; Jürgen Scherer; Silke Schüle; Klaus Cichutek
Safety assessment of biolistic DNA vaccination.
Methods in molecular biology (Clifton, N.J.) 2013;940():371-88.
2012: Ferdinand Kopietz; Melanie Krämer; Heide Muckenfuss; Klaus Cichutek; Egbert Flory; Ananda Ayyappan Jaguva Vasudevan; Ralf Sanzenbacher; Carsten Münk
Interaction of human immunodeficiency virus type 1 Vif with APOBEC3G is not dependent on serine/threonine phosphorylation status.
The Journal of general virology 2012;93(Pt 11):2425-30.
2011: T Schaser; Barbara S Schnierle; Katja Sliva; C Wrede; Klaus Cichutek; L Duerner; Christian J Buchholz
RNAi-mediated gene silencing in tumour tissue using replication-competent retroviral vectors.
Gene therapy 2011;18(10):953-60.
2011: Irene C Schneider; Julia Brynza; Klaus Cichutek; Mary K Collins; Manon Eckhardt; Christian J Buchholz
Escape from R-peptide deletion in a γ-retrovirus.
Virology 2011;418(2):85-92.
2011: Barbara Langer; Klaus Cichutek
[Clinical application of gene therapy. Previous experience and the future].
Pharmazie in unserer Zeit 2011;40(3):254-62.
2011: Eva Dörrschuck; Nicole Fischer; Ignacio G Bravo; Kay-Martin Hanschmann; Heidi Kuiper; Andreas Spötter; Ronny Möller; Klaus Cichutek; Carsten Münk; Ralf R Tönjes
Restriction of porcine endogenous retrovirus by porcine APOBEC3 cytidine deaminases.
Journal of virology 2011;85(8):3842-57.
2011: Robert C Münch; Michael Mühlebach; Thomas Schaser; Sabrina Kneissl; Christian Jost; Andreas Plückthun; Klaus Cichutek; Christian J Buchholz
DARPins: an efficient targeting domain for lentiviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(4):686-93.
2011: Elena Grabski; Zoe Waibler; Silke Schüle; Björn-Philipp Kloke; Linda Y Sender; Sylvia Panitz; Klaus Cichutek; Matthias Schweizer; Ulrich Kalinke
Comparative analysis of transduced primary human dendritic cells generated by the use of three different lentiviral vector systems.
Molecular biotechnology 2011;47(3):262-9.
2011: Ulrich Tschulena; Ralf Sanzenbacher; Michael Mühlebach; André Berger; Jan Münch; Michael Schindler; Frank Kirchhoff; Roland Plesker; Cheick Coulibaly; Sylvia Panitz; Steffen Prüfer; Heide Muckenfuss; Matthias Hamdorf; Matthias Schweizer; Klaus Cichutek; Egbert Flory
Mutation of a diacidic motif in SIV-PBj Nef impairs T-cell activation and enteropathic disease.
Retrovirology 2011;8():14.
2010: Brigitte Anliker; Tobias Abel; Sabrina Kneissl; Juraj Hlavaty; Antonio Caputi; Julia Brynza; Irene C Schneider; Robert C Münch; Helga Petznek; Roland E Kontermann; Ulrike Koehl; Ian Johnston; Kari Keinänen; Ulrike C Müller; Christine Hohenadl; Hannah Monyer; Klaus Cichutek; Christian J Buchholz
Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectors.
Nature methods 2010;7(11):929-35.
2010: Michael Mühlebach; Thomas Schaser; Martina Zimmermann; Sorin Armeanu; Kay-Martin O Hanschmann; Roberto Cattaneo; Michael Bitzer; Ulrich M Lauer; Klaus Cichutek; Christian J Buchholz
Liver cancer protease activity profiles support therapeutic options with matrix metalloproteinase-activatable oncolytic measles virus.
Cancer research 2010;70(19):7620-9.
2010: Hildegard Büning; Wolfgang Uckert; Klaus Cichutek; Robert E Hawkins; Hinrich Abken
Do CARs need a driver's license? Adoptive cell therapy with chimeric antigen receptor-redirected T cells has caused serious adverse events.
Human gene therapy 2010;21(9):1039-42.
2010: Björn-Philipp Kloke; Silke Schüle; Michael Mühlebach; Nina Wolfrum; Klaus Cichutek; Matthias Schweizer
Functional HIV-2- and SIVsmmPBj- derived lentiviral vectors generated by a novel polymerase chain reaction-based approach.
The journal of gene medicine 2010;12(5):446-52.
2010: André Berger; Carsten Münk; Matthias Schweizer; Klaus Cichutek; Silke Schüle; Egbert Flory
Interaction of Vpx and apolipoprotein B mRNA-editing catalytic polypeptide 3 family member A (APOBEC3A) correlates with efficient lentivirus infection of monocytes.
The Journal of biological chemistry 2010;285(16):12248-54.
2010: Mario Perković; Stephen Norley; Ralf Sanzenbacher; Marion Battenberg; Sylvia Panitz; Cheick Coulibaly; Egbert Flory; Christine Siegismund; Carsten Münk; Klaus Cichutek
SIVagm containing the SHIV89.6P Envelope gene replicates poorly and is non-pathogenic.
Virology 2010;399(1):87-97.
2009: Jörg Zielonka; Ignacio G Bravo; Daniela Marino; Elea Conrad; Mario Perković; Marion Battenberg; Klaus Cichutek; Jörg Zielonka
Restriction of equine infectious anemia virus by equine APOBEC3 cytidine deaminases.
Journal of virology 2009;83(15):7547-59.
2009: Benjamin Stauch; Henning Hofmann; Mario Perkovic; Martin Weisel; Ferdinand Kopietz; Klaus Cichutek; Carsten Münk; Gisbert Schneider
Model structure of APOBEC3C reveals a binding pocket modulating ribonucleic acid interaction required for encapsidation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(29):12079-84.
2009: Christian J Buchholz; Michael Mühlebach; Klaus Cichutek
Lentiviral vectors with measles virus glycoproteins - dream team for gene transfer?
Trends in biotechnology 2009;27(5):259-65.
2009: S Funke; I C Schneider; S Glaser; Michael Mühlebach; T Moritz; Roberto Cattaneo; Klaus Cichutek; Christian J Buchholz
Pseudotyping lentiviral vectors with the wild-type measles virus glycoproteins improves titer and selectivity.
Gene therapy 2009;16(5):700-5.
2009: Mario Perkovic; Stanislaw Schmidt; Daniela Marino; Rebecca A Russell; Benjamin Stauch; Henning Hofmann; Ferdinand Kopietz; Björn-Philipp Kloke; Jörg Zielonka; Heike Ströver; Johannes Hermle; Dirk Lindemann; Vinay Pathak; Gisbert Schneider; Martin Löchelt; Klaus Cichutek; Jörg Zielonka
Species-specific inhibition of APOBEC3C by the prototype foamy virus protein bet.
The Journal of biological chemistry 2009;284(9):5819-26.
2009: Silke Schüle; Björn-Philipp Kloke; Julia K Kaiser; Sabine Heidmeier; Sylvia Panitz; Nina Wolfrum; Klaus Cichutek; Matthias Schweizer
Restriction of HIV-1 replication in monocytes is abolished by Vpx of SIVsmmPBj.
PloS one 2009;4(9):e7098.
2009: Carolyn A Wilson; Klaus Cichutek
The US and EU regulatory perspectives on the clinical use of hematopoietic stem/progenitor cells genetically modified ex vivo by retroviral vectors.
Methods in molecular biology (Clifton, N.J.) 2009;506():477-88.
2008: L J Duerner; A Schwantes; I C Schneider; Klaus Cichutek; Christian J Buchholz
Cell entry targeting restricts biodistribution of replication-competent retroviruses to tumour tissue.
Gene therapy 2008;15(22):1500-10.
2008: Sabrina Funke; Andrea Maisner; Michael Mühlebach; Ulrike Koehl; Manuel Grez; Roberto Cattaneo; Klaus Cichutek; Christian J Buchholz
Targeted cell entry of lentiviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(8):1427-36.
2008: Yuansheng Sun; Mingxia Song; Elke Jäger; Christina Schwer; Stefan Stevanovic; Sven Flindt; Julia Karbach; Xuan D Nguyen; Dirk Schadendorf; Klaus Cichutek
Human CD4+ T lymphocytes recognize a vascular endothelial growth factor receptor-2-derived epitope in association with HLA-DR.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(13):4306-15.
2008: Immanuel Barth; Hartmut Krafft; Gabriele Weber; B Keller-Stanislawski; Klaus Cichutek
Good clinical practice in the European Union.
Human gene therapy 2008;19(5):441-2.
2008: Carsten Münk; Thomas Beck; Jörg Zielonka; Agnes Hotz-Wagenblatt; Sarah Chareza; Marion Battenberg; Jens Thielebein; Klaus Cichutek; Ignacio G Bravo; Stephen J O'Brien; Martin Löchelt; Naoya Yuhki
Functions, structure, and read-through alternative splicing of feline APOBEC3 genes.
Genome biology 2008;9(3):R48.
2008: Jürgen Scherer; Thomas Hinz; Klaus Cichutek
[Trends in vaccine development].
Pharmazie in unserer Zeit 2008;37(1):86-92.
2007: Ralf Sanzenbacher; Anne Dwenger; Martina Schuessler-Lenz; Klaus Cichutek; Egbert Flory
European regulation tackles tissue engineering.
Nature biotechnology 2007;25(10):1089-91.
2007: Nina Wolfrum; Michael Mühlebach; Silke Schüle; Julia K Kaiser; Björn-Philipp Kloke; Klaus Cichutek; Matthias Schweizer
Impact of viral accessory proteins of SIVsmmPBj on early steps of infection of quiescent cells.
Virology 2007;364(2):330-41.
2007: Carsten Münk; Jörg Zielonka; Hannelore Constabel; Björn-Philipp Kloke; Benjamin Rengstl; Marion Battenberg; Francesca Bonci; Mauro Pistello; Martin Löchelt; Klaus Cichutek
Multiple restrictions of human immunodeficiency virus type 1 in feline cells.
Journal of virology 2007;81(13):7048-60.
2007: Heide Muckenfuss; Julia K Kaiser; Erika Krebil; Marion Battenberg; Christina Schwer; Klaus Cichutek; Carsten Münk; Egbert Flory
Sp1 and Sp3 regulate basal transcription of the human APOBEC3G gene.
Nucleic acids research 2007;35(11):3784-96.
2006: Christian J Buchholz; Klaus Cichutek
Is it going to be SIN?: a European Society of Gene Therapy commentary. Phasing-out the clinical use of non self-inactivating murine leukemia virus vectors: initiative on hold.
The journal of gene medicine 2006;8(10):1274-6.
2006: Thomas Hinz; Christian J Buchholz; Ton van der Stappen; Klaus Cichutek; Ulrich Kalinke
Manufacturing and quality control of cell-based tumor vaccines: a scientific and a regulatory perspective.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2006;29(5):472-6.
2006: Heide Muckenfuss; Matthias Hamdorf; Ulrike Held; Mario Perkovic; Johannes Löwer; Klaus Cichutek; Egbert Flory; Gerald G Schumann; Carsten Münk
APOBEC3 proteins inhibit human LINE-1 retrotransposition.
The Journal of biological chemistry 2006;281(31):22161-72.
2006: Jeanette Neumann; Jörn Stitz; Renate König; Eric Seibold; Stephen Norley; Egbert Flory; Klaus Cichutek
Retroviral vectors for vaccine development: induction of HIV-1-specific humoral and cellular immune responses in rhesus macaques using a novel MLV(HIV-1) pseudotype vector.
Journal of biotechnology 2006;124(3):615-25.
2006: Silke Schüle; Stefanie Steidl; Sylvia Panitz; Cheick Coulibaly; Ulrich Kalinke; Klaus Cichutek; Matthias Schweizer
Selective gene transfer to T lymphocytes using coreceptor-specific [MLV(HIV)] pseudotype vectors in a transgenic mouse model.
Virology 2006;351(1):237-47.
2006: Jörn Stitz; Nina Wolfrum; Christian J Buchholz; Klaus Cichutek
Envelope proteins of spleen necrosis virus form infectious human immunodeficiency virus type 1 pseudotype vector particles, but fail to incorporate upon substitution of the cytoplasmic domain with that of Gibbon ape leukemia virus.
The Journal of general virology 2006;87(Pt 6):1577-81.
2006: Matthias Hamdorf; Heide Muckenfuss; Ulrich Tschulena; Stephan Pleschka; Ralf Sanzenbacher; Klaus Cichutek; Egbert Flory
An inducible T7 RNA polymerase-dependent plasmid system.
Molecular biotechnology 2006;33(1):13-21.
2006: Heide Muckenfuss; Matthias Hamdorf; Andris Avots; Ralf Sanzenbacher; Ulrich Tschulena; Klaus Cichutek; Egbert Flory
IL-2 induction by simian immunodeficiency virus involves MAP kinase signaling but is independent of calcineurin/NF-AT activity.
Molecular immunology 2006;43(8):1172-82.
2006: Yuansheng Sun; Stefan Stevanovic; Mingxia Song; Astrid Schwantes; C James Kirkpatrick; Dirk Schadendorf; Klaus Cichutek
The kinase insert domain-containing receptor is an angiogenesis-associated antigen recognized by human cytotoxic T lymphocytes.
Blood 2006;107(4):1476-83.
2006: Klaus Cichutek
Lessons learned from gene therapy concerning and the use of integrating vectors and the possible risk of insertional oncogenesis.
Developments in biologicals 2006;123():29-34; discussion 55-73.
2006: Christoph A Merten; Jörn Stitz; Gundula Braun; Julia Medvedovska; Klaus Cichutek; Christian J Buchholz
Fusoselect: cell-cell fusion activity engineered by directed evolution of a retroviral glycoprotein.
Nucleic acids research 2006;34(5):e41.
2005: Michael Mühlebach; Nina Wolfrum; Silke Schüle; Ulrich Tschulena; Ralf Sanzenbacher; Egbert Flory; Klaus Cichutek; Matthias Schweizer
Stable transduction of primary human monocytes by simian lentiviral vector PBj.
Molecular therapy : the journal of the American Society of Gene Therapy 2005;12(6):1206-16.
2005: Yuansheng Sun; Carsten Finger; Luis Alvarez-Vallina; Klaus Cichutek; Christian J Buchholz
Chronic gene delivery of interferon-inducible protein 10 through replication-competent retrovirus vectors suppresses tumor growth.
Cancer gene therapy 2005;12(11):900-12.
2005: Irene Hartl; Richard M Schneider; Y Sun; J Medvedovska; M P Chadwick; stephen russell; Klaus Cichutek; Christian J Buchholz
Library-based selection of retroviruses selectively spreading through matrix metalloprotease-positive cells.
Gene therapy 2005;12(11):918-26.
2005: Martin Löchelt; Fabian Romen; Patrizia Bastone; Heide Muckenfuss; Nadine Kirchner; Yong-Boum Kim; Uwe Truyen; Uwe Roesler; Marion Battenberg; Ali Saib; Egbert Flory; Klaus Cichutek; Carsten Münk
The antiretroviral activity of APOBEC3 is inhibited by the foamy virus accessory Bet protein.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(22):7982-7.
2005: Carsten Finger; Yuansheng Sun; Laura Sanz; Luis Alvarez-Vallina; Christian J Buchholz; Klaus Cichutek
Replicating retroviral vectors mediating continuous production and secretion of therapeutic gene products from cancer cells.
Cancer gene therapy 2005;12(5):464-74.
2005: Daphne Nikles; Patricia Bach; Klaus Boller; Christoph A Merten; Fabio Montrasio; Frank L Heppner; Adriano Aguzzi; Klaus Cichutek; Ulrich Kalinke; Christian J Buchholz
Circumventing tolerance to the prion protein (PrP): vaccination with PrP-displaying retrovirus particles induces humoral immune responses against the native form of cellular PrP.
Journal of virology 2005;79(7):4033-42.
2005: H Krafft; Klaus Cichutek
[Approval of clinical trials of immunobiological medicinal products at the Paul Ehrlich Institute].
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 2005;48(2):168-72.
2005: Johannes H Urban; Richard M Schneider; Marta Compte; Carsten Finger; Klaus Cichutek; Luis Alvarez-Vallina; Christian J Buchholz
Selection of functional human antibodies from retroviral display libraries.
Nucleic acids research 2005;33(4):e35.
2005: Christoph A Merten; Jörn Stitz; Gundula Braun; Eric M Poeschla; Klaus Cichutek; Christian J Buchholz
Directed evolution of retrovirus envelope protein cytoplasmic tails guided by functional incorporation into lentivirus particles.
Journal of virology 2005;79(2):834-40.
2004: Stefanie Steidl; Silke Schüle; Michael Mühlebach; Jörn Stitz; Klaus Boller; Klaus Cichutek; Matthias Schweizer
Genetic engineering of onco/lentivirus hybrids results in formation of infectious but not of replication-competent viruses.
The Journal of general virology 2004;85(Pt 3):665-78.
2003: Michael Mühlebach; Isabel Schmitt; Stefanie Steidl; Jörn Stitz; Matthias Schweizer; Thomas Blankenstein; Klaus Cichutek; Wolfgang Uckert
Transduction efficiency of MLV but not of HIV-1 vectors is pseudotype dependent on human primary T lymphocytes.
Journal of molecular medicine (Berlin, Germany) 2003;81(12):801-10.
2003: Richard M Schneider; Y Medvedovska; Irene Hartl; B Voelker; M P Chadwick; stephen russell; Klaus Cichutek; Christian J Buchholz
Directed evolution of retroviruses activatable by tumour-associated matrix metalloproteases.
Gene therapy 2003;10(16):1370-80.
2003: Christoph A Merten; Martin Engelstaedter; Christian J Buchholz; Klaus Cichutek
Displaying epidermal growth factor on spleen necrosis virus-derived targeting vectors.
Virology 2003;305(1):106-14.
2002: Odile Cohen-Haguenauer; Felicia Rosenthal; Bernd Gänsbacher; Reinder L H Bolhuis; Karoline Dorsch-Häsler; Zelig Eshhar; Gösta Gahrton; Peter Hokland; Cecilia Melani; Elaine Rankin; Kris Thielemans; Richard Vile; Heinz Zwierzina; Klaus Cichutek
Opinion paper on the current status of the regulation of gene therapy in Europe.
Human gene therapy 2002;13(17):2085-110.
2002: Renate König; Egbert Flory; Stefanie Steidl; Jeanette Neumann; Cheick Coulibaly; Edgar Holznagel; Silke Holzammer; Stephen Norley; Klaus Cichutek
Engineered CD4- and CXCR4-using simian immunodeficiency virus from African green monkeys is neutralization sensitive and replicates in nonstimulated lymphocytes.
Journal of virology 2002;76(21):10627-36.
2002: Stefanie Steidl; Jörn Stitz; Isabel Schmitt; Renate König; Egbert Flory; Matthias Schweizer; Klaus Cichutek
Coreceptor Switch of [MLV(SIVagm)] pseudotype vectors by V3-loop exchange.
Virology 2002;300(2):205-16.
2002: Maria Bobkova; Jörn Stitz; Martin Engelstädter; Klaus Cichutek; Christian J Buchholz
Identification of R-peptides in envelope proteins of C-type retroviruses.
The Journal of general virology 2002;83(Pt 9):2241-6.
2001: Jörn Stitz; Michael Mühlebach; Ulrike Blömer; Michaela Scherr; M Selbert; P Wehner; Stefanie Steidl; Isabel Schmitt; Renate König; Matthias Schweizer; Klaus Cichutek
A novel lentivirus vector derived from apathogenic simian immunodeficiency virus.
Virology 2001;291(2):191-7.
2001: Martin Engelstädter; Christian J Buchholz; Maria Bobkova; Stefanie Steidl; H Merget-Millitzer; R A Willemsen; Jörn Stitz; Klaus Cichutek
Targeted gene transfer to lymphocytes using murine leukaemia virus vectors pseudotyped with spleen necrosis virus envelope proteins.
Gene therapy 2001;8(15):1202-6.
2000: Jörn Stitz; Christian J Buchholz; Martin Engelstädter; Wolfgang Uckert; U Bloemer; Isabel Schmitt; Klaus Cichutek
Lentiviral vectors pseudotyped with envelope glycoproteins derived from gibbon ape leukemia virus and murine leukemia virus 10A1.
Virology 2000;273(1):16-20.
2000: Zahida Parveen; A Krupetsky; Martin Engelstädter; Klaus Cichutek; Roger J Pomerantz; Ralph Dornburg
Spleen necrosis virus-derived C-type retroviral vectors for gene transfer to quiescent cells.
Nature biotechnology 2000;18(6):623-9.
2000: Jörn Stitz; Stefanie Steidl; H Merget-Millitzer; Renate König; P Müller; Frank Nocken; Martin Engelstädter; Maria Bobkova; Isabel Schmitt; Reinhard Kurth; Christian J Buchholz; Klaus Cichutek
MLV-derived retroviral vectors selective for CD4-expressing cells and resistant to neutralization by sera from HIV-infected patients.
Virology 2000;267(2):229-36.
2000: Martin Engelstädter; Maria Bobkova; M Baier; Jörn Stitz; N Holtkamp; TH Chu; Reinhard Kurth; Ralph Dornburg; Christian J Buchholz; Klaus Cichutek
Targeting human T cells by retroviral vectors displaying antibody domains selected from a phage display library.
Human gene therapy 2000;11(2):293-303.
2000: Klaus Cichutek
DNA vaccines: development, standardization and regulation.
Intervirology 2000;43(4-6):331-8.
2000: Klaus Cichutek
Regulatory aspects of cancer gene therapy and DNA vaccination.
Ernst Schering Research Foundation workshop 2000;(30):181-9.
1999: Christian J Buchholz; Jörn Stitz; Klaus Cichutek
Retroviral cell targeting vectors.
Current opinion in molecular therapeutics 1999;1(5):613-21.
1999: Klaus Cichutek
Development and standardisation of DNA vaccines.
Developments in biological standardization 1999;100():119-29.
1998: A Jiang; TH Chu; Frank Nocken; Klaus Cichutek; Ralph Dornburg
Cell-type-specific gene transfer into human cells with retroviral vectors that display single-chain antibodies.
Journal of virology 1998;72(12):10148-56.
1998: Stefan Wagener; M T Dittmar; Brigitte E Beer; Renate König; Roland Plesker; Stephen Norley; Reinhard Kurth; Klaus Cichutek
The U3 promoter and the nef gene of simian immunodeficiency virus (SIV) smmPBj1.9 do not confer acute pathogenicity upon SIVagm.
Journal of virology 1998;72(4):3446-50.
1997: Barbara S Schnierle; Jörn Stitz; V Bosch; Frank Nocken; H Merget-Millitzer; Martin Engelstädter; Reinhard Kurth; Bernd Groner; Klaus Cichutek
Pseudotyping of murine leukemia virus with the envelope glycoproteins of HIV generates a retroviral vector with specificity of infection for CD4-expressing cells.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(16):8640-5.
1997: P Müller; Martin Engelstädter; A Werner; J Braner; S Staszewski; V Miller; H W Doerr; Reinhard Kurth; Klaus Cichutek
Increased serum and mRNA levels of RANTES associated with elevated levels of activated CD8+CD38+ T cells in HIV-1 infected individuals.
Intervirology 1997;40(4):263-70.
1996: Brigitte E Beer; Stephen Norley; Klaus Cichutek; Reinhard Kurth
Control of initial viraemia coincides with neutralizing antibody response after SIVmac infection of rhesus macaques.
AIDS (London, England) 1996;10(6):681-2.
1996: Stefan Wagener; Stephen Norley; Jan zur Megede; Reinhard Kurth; Klaus Cichutek
Induction of antibodies against SIV antigens after intramuscular nucleic acid inoculation using complex expression constructs.
Journal of biotechnology 1996;44(1-3):59-65.
1996: M T Dittmar; Stefan Wagener; P Fultz; Reinhard Kurth; Klaus Cichutek
An in vitro assay for acute pathogenicity of immunodeficiency viruses.
Developments in biological standardization 1996;86():167-73.
1995: Klaus Cichutek
Obtaining marketing authorization for nucleic acid vaccines in the European Union.
Annals of the New York Academy of Sciences 1995;772():178-85.
1995: M T Dittmar; Klaus Cichutek; P N Fultz; Reinhard Kurth
The U3 promoter region of the acutely lethal simian immunodeficiency virus clone smmPBj1.9 confers related biological activity on the apathogenic clone agm3mc.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(5):1362-6.
1994: Klaus Cichutek
Nucleic acid immunization: a prophylactic gene therapy?
Vaccine 1994;12(16):1520-5.
1994: M Lang; I Treinies; P H Duesberg; Reinhard Kurth; Klaus Cichutek
Development of transforming function during transduction of proto-ras into Harvey sarcoma virus.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(2):654-8.
1993: M Vogel; Klaus Cichutek; Stephen Norley; Reinhard Kurth
Self-limiting infection by int/nef-double mutants of simian immunodeficiency virus.
Virology 1993;193(1):115-23.
1993: Klaus Cichutek; Stephen Norley
Lack of immune suppression in SIV-infected natural hosts.
AIDS (London, England) 1993;7 Suppl 1():S25-35.
1992: Klaus Cichutek; H Merget; Stephen Norley; Richard Linde; Wolfhart Kreuz; M Gahr; Reinhard Kurth
Development of a quasispecies of human immunodeficiency virus type 1 in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7365-9.
1992: S Hartung; Klaus Boller; Klaus Cichutek; Stephen Norley; Reinhard Kurth
Quantitation of a lentivirus in its natural host: simian immunodeficiency virus in African green monkeys.
Journal of virology 1992;66(4):2143-9.
1992: S Hartung; Stephen Norley; J Ennen; Klaus Cichutek; Roland Plesker; Reinhard Kurth
Vaccine protection against SIVmac infection by high- but not low-dose whole inactivated virus immunogen.
Journal of acquired immune deficiency syndromes 1992;5(5):461-8.
1991: Klaus Cichutek; Stephen Norley; Richard Linde; Wolfhart Kreuz; M Gahr; Johannes Löwer; G von Wangenheim; Reinhard Kurth
Lack of HIV-1 V3 region sequence diversity in two haemophiliac patients infected with a putative biologic clone of HIV-1.
AIDS (London, England) 1991;5(10):1185-7.
1991: M Baier; M T Dittmar; Klaus Cichutek; Reinhard Kurth
Development of vivo of genetic variability of simian immunodeficiency virus.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(18):8126-30.
1991: A K Chakraborty; Klaus Cichutek; P H Duesberg
Transforming function of proto-ras genes depends on heterologous promoters and is enhanced by specific point mutations.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2217-21.
1991: Reinhard Kurth; M Baier; D Binninger; Klaus Cichutek; Johannes Löwer; Stephen Norley
Epidemiology and pathogenicity of human retroviruses.
Developments in biological standardization 1991;75():105-11.
1990: A Werner; G Winskowsky; Klaus Cichutek; Stephen Norley; Reinhard Kurth
Productive infection of both CD4+ and CD4- human cell lines with HIV-1, HIV-2 and SIVagm.
AIDS (London, England) 1990;4(6):537-44.
1990: M Baier; C Garber; C Müller; Klaus Cichutek; Reinhard Kurth
Complete nucleotide sequence of a simian immunodeficiency virus from African green monkeys: a novel type of intragroup divergence.
Virology 1990;176(1):216-21.
1990: A Werner; M Baier; Klaus Cichutek; Reinhard Kurth
SIV grows unchanged in human cells.
Nature 1990;344(6262):113.
1989: M Baier; A Werner; Klaus Cichutek; C Garber; C Müller; Gunter Kraus; F J Ferdinand; S Hartung; T S Papas; Reinhard Kurth
Molecularly cloned simian immunodeficiency virus SIVagm3 is highly divergent from other SIVagm isolates and is biologically active in vitro and in vivo.
Journal of virology 1989;63(12):5119-23.
1989: Klaus Cichutek; P H Duesberg
Recombinant BALB and Harvey sarcoma viruses with normal proto-ras-coding regions transform embryo cells in culture and cause tumors in mice.
Journal of virology 1989;63(3):1377-83.
1987: Klaus Cichutek; P H Duesberg
Conversion of ras genes to cancer genes.
Haematology and blood transfusion 1987;31():477-81.
1986: Klaus Cichutek; P H Duesberg
Harvey ras genes transform without mutant codons, apparently activated by truncation of a 5' exon (exon -1).
Proceedings of the National Academy of Sciences of the United States of America 1986;83(8):2340-4.