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Kevin Claffey

Research Profile

Chemicals & Drugs

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TOP 3
Luke H Hoeppner; Kathryn N Phoenix; Tracey E Sciuto; Sandip Suresh; Pawan Vohra; Resham Bhattacharya; Santanu Bhattacharya; Kevin P Claffey; Karl Clark; Ann M Dvorak; Harold F Dvorak; Stephen C Ekker; Xun Gong; Debabrata Mukhopadhyay
Revealing the role of phospholipase Cβ3 in the regulation of VEGF-induced vascular permeability.
I K Guttilla; X Hong; K N Phoenix; Jennifer Tirnauer; Kevin P Claffey; B A White
Prolonged mammosphere culture of MCF-7 cells induces an EMT and repression of the estrogen receptor by microRNAs.
Kathryn N Phoenix; Laura E Stevens; Charan V Devarakonda; Melissa M Fox; Kevin P Claffey
AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis.

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All Publications

2012: Luke H Hoeppner; Kathryn N Phoenix; Tracey E Sciuto; Sandip Suresh; Pawan Vohra; Resham Bhattacharya; Santanu Bhattacharya; Kevin P Claffey; Karl Clark; Ann M Dvorak; Harold F Dvorak; Stephen C Ekker; Xun Gong; Debabrata Mukhopadhyay
Revealing the role of phospholipase Cβ3 in the regulation of VEGF-induced vascular permeability.
Blood 2012;120(11):2167-73.
2012: I K Guttilla; X Hong; K N Phoenix; Jennifer Tirnauer; Kevin P Claffey; B A White
Prolonged mammosphere culture of MCF-7 cells induces an EMT and repression of the estrogen receptor by microRNAs.
Breast cancer research and treatment 2012;132(1):75-85.
2012: Kathryn N Phoenix; Laura E Stevens; Charan V Devarakonda; Melissa M Fox; Kevin P Claffey
AMPKα2 Suppresses Murine Embryonic Fibroblast Transformation and Tumorigenesis.
Genes & cancer 2012;3(1):51-62.
2012: Christina L Grant; Mohammed Mamunur Rahman; Vivienne Ho; Leslie A Caromile; Kevin P Claffey; Khayyam Durrani; Guo-Hua Fong; Linda H. Shapiro
Prostate specific membrane antigen (PSMA) regulates angiogenesis independently of VEGF during ocular neovascularization.
PloS one 2012;7(7):e41285.
2010: Kathryn N Phoenix; Frank Vumbaca; Melissa M Fox; Rebecca Evans; Kevin P Claffey
Dietary energy availability affects primary and metastatic breast cancer and metformin efficacy.
Breast cancer research and treatment 2010;123(2):333-44.
2004: Anshu Agarwal; Ursula Muñoz-Nájar; Ulrike Klueh; Shu-Ching Shih; Kevin P Claffey
N-acetyl-cysteine promotes angiostatin production and vascular collapse in an orthotopic model of breast cancer.
The American journal of pathology 2004;164(5):1683-96.
2001: Mihaela Skobe; Thomas Hawighorst; David G Jackson; Remko Prevo; Lauren Janes; Paula Velasco; Lucia Riccardi; Kari Alitalo; Kevin P Claffey; Michael Detmar
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis.
Nature medicine 2001;7(2):192-8.
2001: SC Shih; Kevin P Claffey
Role of AP-1 and HIF-1 transcription factors in TGF-beta activation of VEGF expression.
Growth factors (Chur, Switzerland) 2001;19(1):19-34.
2001: Kevin P Claffey; K Abrams; S C Shih; Lawrence F Brown; A Mullen; Martin P Keough
Fibroblast growth factor 2 activation of stromal cell vascular endothelial growth factor expression and angiogenesis.
Laboratory investigation; a journal of technical methods and pathology 2001;81(1):61-75.
2000: Michael Detmar; Paula Velasco; L Richard; Kevin P Claffey; Michael Streit; Lucia Riccardi; Mihaela Skobe; Lawrence F Brown
Expression of vascular endothelial growth factor induces an invasive phenotype in human squamous cell carcinomas.
The American journal of pathology 2000;156(1):159-67.
1999: S C Shih; A Mullen; K Abrams; Debabrata Mukhopadhyay; Kevin P Claffey
Role of protein kinase C isoforms in phorbol ester-induced vascular endothelial growth factor expression in human glioblastoma cells.
The Journal of biological chemistry 1999;274(22):15407-14.
1999: S C Shih; Kevin P Claffey
Regulation of human vascular endothelial growth factor mRNA stability in hypoxia by heterogeneous nuclear ribonucleoprotein L.
The Journal of biological chemistry 1999;274(3):1359-65.
1998: SC Shih; Kevin P Claffey
Hypoxia-mediated regulation of gene expression in mammalian cells.
International journal of experimental pathology 1998;79(6):347-57.
1998: S Pal; Kevin P Claffey; H T Cohen; Debabrata Mukhopadhyay
Activation of Sp1-mediated vascular permeability factor/vascular endothelial growth factor transcription requires specific interaction with protein kinase C zeta.
The Journal of biological chemistry 1998;273(41):26277-80.
1998: J Boesiger; Mindy Tsai; Marcus Maurer; M Yamaguchi; Lawrence F Brown; Kevin P Claffey; Harold F Dvorak; Stephen J Galli
Mast cells can secrete vascular permeability factor/ vascular endothelial cell growth factor and exhibit enhanced release after immunoglobulin E-dependent upregulation of fc epsilon receptor I expression.
The Journal of experimental medicine 1998;188(6):1135-45.
1998: Michael Detmar; Lawrence F Brown; M P Schön; B M Elicker; Paula Velasco; L Richard; D Fukumura; Wayne L Monsky; Kevin P Claffey; R K Jain
Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice.
The Journal of investigative dermatology 1998;111(1):1-6.
1998: Kevin P Claffey; SC Shih; A Mullen; Suzan Dziennis; J L Cusick; K R Abrams; S W Lee; Michael Detmar
Identification of a human VPF/VEGF 3' untranslated region mediating hypoxia-induced mRNA stability.
Molecular biology of the cell 1998;9(2):469-81.
1997: Donald R Senger; Kevin P Claffey; J E Benes; Carole A Perruzzi; A P Sergiou; Michael Detmar
Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13612-7.
1997: Soumitro Pal; Kevin P Claffey; Harold F Dvorak; Debabrata Mukhopadhyay
The von Hippel-Lindau gene product inhibits vascular permeability factor/vascular endothelial growth factor expression in renal cell carcinoma by blocking protein kinase C pathways.
The Journal of biological chemistry 1997;272(44):27509-12.
1997: Michael Detmar; Lawrence F Brown; B Berse; Robert Jackman; B M Elicker; Harold F Dvorak; Kevin P Claffey
Hypoxia regulates the expression of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) and its receptors in human skin.
The Journal of investigative dermatology 1997;108(3):263-8.
1997: Lawrence F Brown; Michael Detmar; Kevin P Claffey; Janice A Nagy; D Feng; Ann M Dvorak; Harold F Dvorak
Vascular permeability factor/vascular endothelial growth factor: a multifunctional angiogenic cytokine.
EXS 1997;79():233-69.
1996: D R Senger; S R Ledbetter; Kevin P Claffey; A Papadopoulos-Sergiou; C A Peruzzi; Michael Detmar
Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin.
The American journal of pathology 1996;149(1):293-305.
1996: Kevin P Claffey; G S Robinson
Regulation of VEGF/VPF expression in tumor cells: consequences for tumor growth and metastasis.
Cancer metastasis reviews 1996;15(2):165-76.
1996: Kevin P Claffey; Lawrence F Brown; L F del Aguila; K Tognazzi; K T Yeo; Eleanor J Manseau; Harold F Dvorak
Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis.
Cancer research 1996;56(1):172-81.
1995: Harold F Dvorak; Michael Detmar; Kevin P Claffey; Janice A Nagy; Livingston Van De Water; D R Senger
Vascular permeability factor/vascular endothelial growth factor: an important mediator of angiogenesis in malignancy and inflammation.
International archives of allergy and immunology 1995;107(1-3):233-5.
1995: Kevin P Claffey; D R Senger; Bruce M Spiegelman
Structural requirements for dimerization, glycosylation, secretion, and biological function of VPF/VEGF.
Biochimica et biophysica acta 1995;1246(1):1-9.
1994: Michael Detmar; Lawrence F Brown; Kevin P Claffey; K T Yeo; Olivier Kocher; Robert Jackman; Brygida Berse; Harold F Dvorak
Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis.
The Journal of experimental medicine 1994;180(3):1141-6.
1994: D R Senger; Lawrence F Brown; Kevin P Claffey; Harold F Dvorak
Vascular permeability factor, tumor angiogenesis and stroma generation.
Invasion & metastasis 1994;14(1-6):385-94.