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Brian Clark

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Brian F C Clark
Notes from abroad on the deciphering of biology's Rosetta Stone.
Brian F C Clark
Healthy human ageing.
Michael J Taussig; Christian Suojanen; Brian F C Clark
New Biotechnology and the European Federation of Biotechnology.

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All Publications

2011: Brian F C Clark
Notes from abroad on the deciphering of biology's Rosetta Stone.
Cellular and molecular neurobiology 2011;31(6):815-7.
2008: Brian F C Clark
Healthy human ageing.
New biotechnology 2008;25(1):13-5.
2008: Michael J Taussig; Christian Suojanen; Brian F C Clark
New Biotechnology and the European Federation of Biotechnology.
New biotechnology 2008;25(1):1-2.
2007: Jan Barciszewski; Frank Massino; Brian F C Clark
Kinetin--a multiactive molecule.
International journal of biological macromolecules 2007;40(3):182-92.
2006: Brian F C Clark
The crystal structure of tRNA.
Journal of biosciences 2006;31(4):453-7.
2006: Regina Gonzalez-Dosal; Morten Draeby Sørensen; Brian F C Clark; Suresh Rattan; Peter Kristensen
Phage-displayed antibodies for the detection of glycated proteasome in aging cells.
Annals of the New York Academy of Sciences 2006;1067():474-8.
2005: Huber R Warner; Julie Anderson; Steven Austad; Ettore Bergamini; Dale E Bredesen; Robert Butler; Bruce A Carnes; Brian F C Clark; Vincent J Cristofalo; John A Faulkner; Leonard Guarente; David E Harrison; Tom Kirkwood; Gordon J Lithgow; George Martin; Ed Masoro; Simon Melov; Richard A Miller; S Jay Olshansky; Linda Partridge; Olivia M Pereira-Smith; Tom Perls; Arlan G Richardson; James Smith; Thomas von Zglinicki; Eugenia Wang; Jeanne Y Wei; T Franklin Williams
Science fact and the SENS agenda. What can we reasonably expect from ageing research?
EMBO reports 2005;6(11):1006-8.
2005: Suresh Rattan; Brian F C Clark
Understanding and modulating ageing.
IUBMB life 2005;57(4-5):297-304.
2005: Francisco Mansilla; Lise Lotte Hansen; Helle Jakobsen; Niels Ole Kjeldgaard; Brian F C Clark; Charlotte R Knudsen
Deconstructing PTI-1: PTI-1 is a truncated, but not mutated, form of translation elongatin factor 1A1, eEF1A1.
Biochimica et biophysica acta 2005;1727(2):116-24.
2005: Eric Matthews; Erica Haimes; Anne-Marie Duguet; Brian F C Clark; Christian Swine; Olivier Toussaint
Informed consent of very old patients and modern genomics.
Biogerontology 2005;6(1):81-4.
2004: Rasmus Beedholm; Brian F C Clark; Suresh Rattan
Mild heat stress stimulates 20S proteasome and its 11S activator in human fibroblasts undergoing aging in vitro.
Cell stress & chaperones 2004;9(1):49-57.
2004: Henrik Karring; Sander G J Mathu; Jan van Duin; Brian F C Clark; Barend Kraal; Charlotte R Knudsen
Qbeta-phage resistance by deletion of the coiled-coil motif in elongation factor Ts.
The Journal of biological chemistry 2004;279(3):1878-84.
2003: Henrik Karring; Asgeir Bjornsson; Søren Thirup; Brian F C Clark; Charlotte R Knudsen
Functional effects of deleting the coiled-coil motif in Escherichia coli elongation factor Ts.
European journal of biochemistry / FEBS 2003;270(21):4294-305.
2003: Soren Kahns; Michael Kalai; Lene Diness Jakobsen; Brian F C Clark; Peter Vandenabeele; Poul Henning Jensen
Caspase-1 and caspase-8 cleave and inactivate cellular parkin.
The Journal of biological chemistry 2003;278(26):23376-80.
2003: William J Whelan; Hans L Kornberg; Bruce A Stone; E C Slater; Peter Campbell; Chen-lu Tsou; Frank Vella; Uriel Z Littauer; Brian F C Clark
54 years of International Congresses of Biochemistry and Molecular Biology.
IUBMB life 2003;55(4-5):183-91.
2003: Eliza Wyszko; Miroslawa Z Barciszewska; Maria Markiewicz; Maciej Szymański; Wojciech T Markiewicz; Brian F C Clark; Jan Barciszewski
"Action-at-a distance" of a new DNA oxidative damage product 6-furfuryl-adenine (kinetin) on template properties of modified DNA.
Biochimica et biophysica acta 2003;1625(3):239-45.
2003: Kim Bak Jensen; Ole N Jensen; Peter Ravn; Brian F C Clark; Peter Kristensen
Identification of keratinocyte-specific markers using phage display and mass spectrometry.
Molecular & cellular proteomics : MCP 2003;2(2):61-9.
2002: Henrik Karring; Gregers R Andersen; Søren Thirup; Jens Nyborg; Linda Spremulli; Brian F C Clark
Isolation, crystallisation, and preliminary X-ray analysis of the bovine mitochondrial EF-Tu:GDP and EF-Tu:EF-Ts complexes.
Biochimica et biophysica acta 2002;1601(2):172-7.
2002: Kim Bak Jensen; Martin Larsen; Jesper Pedersen; Peter Astrup Christensen; Luis Alvarez-Vallina; Steffen Goletz; Brian F C Clark; Peter Kristensen
Functional improvement of antibody fragments using a novel phage coat protein III fusion system.
Biochemical and biophysical research communications 2002;298(4):566-73.
2002: Jannik Fonager; Rasmus Beedholm; Brian F C Clark; Suresh Rattan
Mild stress-induced stimulation of heat-shock protein synthesis and improved functional ability of human fibroblasts undergoing aging in vitro.
Experimental gerontology 2002;37(10-11):1223-8.
2002: Daniel B McClatchy; Charlotte R Knudsen; Brian F C Clark; Richard A Kahn; Randy A Hall; Allan Levey
Novel interaction between the M4 muscarinic acetylcholine receptor and elongation factor 1A2.
The Journal of biological chemistry 2002;277(32):29268-74.
2002: Francisco Mansilla; Irene Friis; Mandana Jadidi; Karen M Nielsen; Brian F C Clark; Charlotte R Knudsen
Mapping the human translation elongation factor eEF1H complex using the yeast two-hybrid system.
The Biochemical journal 2002;365(Pt 3):669-76.
2002: Philippe Verbeke; Marianne Deries; Brian F C Clark; Suresh Rattan
Hormetic action of mild heat stress decreases the inducibility of protein oxidation and glycoxidation in human fibroblasts.
Biogerontology 2002;3(1-2):117-20.
2001: Philippe Verbeke; Brian F C Clark; Suresh Rattan
Reduced levels of oxidized and glycoxidized proteins in human fibroblasts exposed to repeated mild heat shock during serial passaging in vitro.
Free radical biology & medicine 2001;31(12):1593-602.
2001: Brian F C Clark
The crystallization and structural determination of tRNA.
Trends in biochemical sciences 2001;26(8):511-4.
2001: S Kjaer; Troels Wind; Peter Ravn; M Østergaard; Brian F C Clark; A Nissim
Generation and epitope mapping of high-affinity scFv to eukaryotic elongation factor 1A by dual application of phage display.
European journal of biochemistry / FEBS 2001;268(12):3407-15.
2001: B Stausbøl-Grøn; Kim Bak Jensen; Kristina H Jensen; M Ø Jensen ; Brian F C Clark
De novo identification of cell-type specific antibody-antigen pairs by phage display subtraction. Isolation of a human single chain antibody fragment against human keratin 14.
European journal of biochemistry / FEBS 2001;268(10):3099-107.
2001: Amjad H Talukder; HF Jorgensen; Mahitosh Mandal; Sandip K Mishra; Ratna K Vadlamudi; Brian F C Clark; John Mendelsohn; Rakesh Kumar
Regulation of elongation factor-1alpha expression by growth factors and anti-receptor blocking antibodies.
The Journal of biological chemistry 2001;276(8):5636-42.
2001: M Kveiborg; Suresh Rattan; Brian F C Clark; EF Eriksen; Moustapha Kassem
Treatment with 1,25-dihydroxyvitamin D3 reduces impairment of human osteoblast functions during cellular aging in culture.
Journal of cellular physiology 2001;186(2):298-306.
2001: Philippe Verbeke; Jannik Fonager; Brian F C Clark; Suresh Rattan
Heat shock response and ageing: mechanisms and applications.
Cell biology international 2001;25(9):845-57.
2000: Jan Barciszewski; M Mielcarek; Maciej Stobiecki; GE Siboska; Brian F C Clark
Identification of 6-furfuryladenine (kinetin) in human urine.
Biochemical and biophysical research communications 2000;279(1):69-73.
2000: Philippe Verbeke; GE Siboska; Brian F C Clark; Suresh Rattan
Kinetin inhibits protein oxidation and glycoxidation in vitro.
Biochemical and biophysical research communications 2000;276(3):1265-70.
2000: Olivier Toussaint; J Remacle; Brian F C Clark; Efstathios S Gonos; C Franceschi; T B Kirkwood
Biology of ageing.
BioEssays : news and reviews in molecular, cellular and developmental biology 2000;22(10):954-6.
2000: Philippe Verbeke; Brian F C Clark; Suresh Rattan
Modulating cellular aging in vitro: hormetic effects of repeated mild heat stress on protein oxidation and glycation.
Experimental gerontology 2000;35(6-7):787-94.
2000: Claus Bischoff; Soren Kahns; A Lund; H F Jørgensen; Morten Praestegaard; Brian F C Clark; H Leffers
The human elongation factor 1 A-2 gene (EEF1A2): complete sequence and characterization of gene structure and promoter activity.
Genomics 2000;68(1):63-70.
2000: Mette Christiansen; Tinna Stevnsner; Vilhelm A Bohr; Brian F C Clark; Suresh Rattan
Gene-specific DNA repair of pyrimidine dimers does not decline during cellular aging in vitro.
Experimental cell research 2000;256(1):308-14.
2000: Mette Christiansen; M Kveiborg; Moustapha Kassem; Brian F C Clark; Suresh Rattan
CBFA1 and topoisomerase I mRNA levels decline during cellular aging of human trabecular osteoblasts.
The journals of gerontology. Series A, Biological sciences and medical sciences 2000;55(4):B194-200.
2000: Peter Ravn; S Kjaer; Kristina H Jensen; Troels Wind; Kim Bak Jensen; Peter Kristensen; Robert M Brosh; David K Orren; Vilhelm A Bohr; Brian F C Clark
Identification of phage antibodies toward the Werner protein by selection on Western blots.
Electrophoresis 2000;21(3):509-16.
1999: Jan Barciszewski; Miroslawa Z Barciszewska; GE Siboska; Suresh Rattan; Brian F C Clark
Some unusual nucleic acid bases are products of hydroxyl radical oxidation of DNA and RNA.
Molecular biology reports 1999;26(4):231-8.
1999: Troels Wind; S Kjaer; Brian F C Clark
Display of Ras on filamentous phage through cysteine replacement.
Biochimie 1999;81(12):1079-87.
1999: A Olsen; GE Siboska; Brian F C Clark; Suresh Rattan
N(6)-Furfuryladenine, kinetin, protects against Fenton reaction-mediated oxidative damage to DNA.
Biochemical and biophysical research communications 1999;265(2):499-502.
1999: L D Andersen; Juan Manuel Palacios Moreno; Brian F C Clark; Kim Kusk Mortensen; Hans Uffe Sperling-Petersen
Immunochemical determination of cellular content of translation release factor RF4 in Escherichia coli.
IUBMB life 1999;48(3):283-6.
1999: G N Pedersen; J Nyborg; Brian F C Clark
Macromolecular mimicry of nucleic acid and protein.
IUBMB life 1999;48(1):13-8.
1999: Brian F C Clark; Søren Thirup; Morten Kjeldgaard; Jens Nyborg
Structural information for explaining the molecular mechanism of protein biosynthesis.
FEBS letters 1999;452(1-2):41-6.
1999: M Kveiborg; Moustapha Kassem; Bente Langdahl; EF Eriksen; Brian F C Clark; Suresh Rattan
Telomere shortening during aging of human osteoblasts in vitro and leukocytes in vivo: lack of excessive telomere loss in osteoporotic patients.
Mechanisms of ageing and development 1999;106(3):261-71.
1998: Søren Nielsen; Morten Praestegaard; HF Jorgensen; Brian F C Clark
Different Sp1 family members differentially affect transcription from the human elongation factor 1 A-1 gene promoter.
The Biochemical journal 1998;333 ( Pt 3)():511-7.
1998: S Kjaer; B Stausbøl-Grøn; Troels Wind; Peter Ravn; K Hobolt Jensen; L Kahns; Brian F C Clark
Glycerol diversifies phage repertoire selections and lowers non-specific phage absorption.
FEBS letters 1998;431(3):448-52.
1998: Francisco Mansilla; Charlotte R Knudsen; Brian F C Clark
Mutational analysis of Glu272 in elongation factor 1A of E. coli.
FEBS letters 1998;429(3):417-20.
1998: Peter Kristensen; A Lund; Brian F C Clark; J Cavallius; William C Merrick
Purification and characterisation of a tissue specific elongation factor 1 alpha (EF-1 alpha 2) from rabbit muscle.
Biochemical and biophysical research communications 1998;245(3):810-4.
1998: Soren Kahns; A Lund; Peter Kristensen; Charlotte R Knudsen; Brian F C Clark; J Cavallius; William C Merrick
The elongation factor 1 A-2 isoform from rabbit: cloning of the cDNA and characterization of the protein.
Nucleic acids research 1998;26(8):1884-90.
1998: Efstathios S Gonos; A Derventzi; M Kveiborg; Georgia Agiostratidou; M Kassem; Brian F C Clark; Parmjit S Jat; Suresh Rattan
Cloning and identification of genes that associate with mammalian replicative senescence.
Experimental cell research 1998;240(1):66-74.
1998: M Laurberg; Francisco Mansilla; Brian F C Clark; Charlotte R Knudsen
Investigation of functional aspects of the N-terminal region of elongation factor Tu from Escherichia coli using a protein engineering approach.
The Journal of biological chemistry 1998;273(8):4387-91.
1998: G N Pedersen; Thomas Rattenborg; Charlotte R Knudsen; Brian F C Clark
The role of Glu259 in Escherichia coli elongation factor Tu in ternary complex formation.
Protein engineering 1998;11(2):101-8.
1997: Troels Wind; B Stausbøl-Grøn; S Kjaer; L Kahns; Kristina H Jensen; Brian F C Clark
Retrieval of phage displayed scFv fragments using direct bacterial elution.
Journal of immunological methods 1997;209(1):75-83.
1997: Thomas Rattenborg; G Nautrup Pedersen; Brian F C Clark; Charlotte R Knudsen
Contribution of Arg288 of Escherichia coli elongation factor Tu to translational functionality.
European journal of biochemistry / FEBS 1997;249(2):408-14.
1997: Jan Barciszewski; GE Siboska; B O Pedersen; Brian F C Clark; Suresh Rattan
Furfural, a precursor of the cytokinin hormone kinetin, and base propenals are formed by hydroxyl radical damage of DNA.
Biochemical and biophysical research communications 1997;238(2):317-9.
1997: Jan Barciszewski; GE Siboska; B O Pedersen; Brian F C Clark; Suresh Rattan
A mechanism for the in vivo formation of N6-furfuryladenine, kinetin, as a secondary oxidative damage product of DNA.
FEBS letters 1997;414(2):457-60.
1997: Francisco Mansilla; Charlotte R Knudsen; M Laurberg; Brian F C Clark
Mutational analysis of Escherichia coli elongation factor Tu in search of a role for the N-terminal region.
Protein engineering 1997;10(8):927-34.
1997: Brian F C Clark; Jens Nyborg
The ternary complex of EF-Tu and its role in protein biosynthesis.
Current opinion in structural biology 1997;7(1):110-6.
1997: Jens Nyborg; Poul Nissen; Morten Kjeldgaard; Søren Thirup; G Polekhina; Brian F C Clark; L Reshetnikova
Macromolecular mimicry in protein biosynthesis.
Folding & design 1997;2(3):S7-11.
1996: Suresh Rattan; Brian F C Clark
Intracellular protein synthesis, modifications and aging.
Biochemical Society transactions 1996;24(4):1043-9.
1996: Morten Kjeldgaard; Jens Nyborg; Brian F C Clark
The GTP binding motif: variations on a theme.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(12):1347-68.
1996: Jan Barciszewski; GE Siboska; B O Pedersen; Brian F C Clark; Suresh Rattan
Evidence for the presence of kinetin in DNA and cell extracts.
FEBS letters 1996;393(2-3):197-200.
1996: H Norsgaard; Brian F C Clark; Suresh Rattan
Distinction between differentiation and senescence and the absence of increased apoptosis in human keratinocytes undergoing cellular aging in vitro.
Experimental gerontology 1996;31(5):563-70.
1996: O Wiborg; C Andersen; Charlotte R Knudsen; Brian F C Clark; Jens Nyborg
Mapping Escherichia coli elongation factor Tu residues involved in binding of aminoacyl-tRNA.
The Journal of biological chemistry 1996;271(34):20406-11.
1996: B Stausbøl-Grøn; Troels Wind; S Kjaer; L Kahns; N J Hansen; P Kristensen; Brian F C Clark
A model phage display subtraction method with potential for analysis of differential gene expression.
FEBS letters 1996;391(1-2):71-5.
1996: Jens Nyborg; Poul Nissen; Morten Kjeldgaard; Søren Thirup; G Polekhina; Brian F C Clark
Structure of the ternary complex of EF-Tu: macromolecular mimicry in translation.
Trends in biochemical sciences 1996;21(3):81-2.
1996: Poul Nissen; Morten Kjeldgaard; Søren Thirup; Brian F C Clark; Jens Nyborg
The ternary complex of aminoacylated tRNA and EF-Tu-GTP. Recognition of a bond and a fold.
Biochimie 1996;78(11-12):921-33.
1995: Poul Nissen; Morten Kjeldgaard; Søren Thirup; G Polekhina; L Reshetnikova; Brian F C Clark; Jens Nyborg
Crystal structure of the ternary complex of Phe-tRNAPhe, EF-Tu, and a GTP analog.
Science (New York, N.Y.) 1995;270(5241):1464-72.
1995: N J Hansen; P Kristensen; J Lykke; Kim Kusk Mortensen; Brian F C Clark
A fast, economical and efficient method for DNA purification by use of a homemade bead column.
Biochemistry and molecular biology international 1995;35(3):461-5.
1995: Charlotte R Knudsen; I V Kjaersgård; O Wiborg; Brian F C Clark
Mutation of the conserved Gly94 and Gly126 in elongation factor Tu from Escherichia coli. Elucidation of their structural and functional roles.
European journal of biochemistry / FEBS 1995;228(1):176-83.
1994: Poul Nissen; L Reshetnikova; GE Siboska; G Polekhina; Søren Thirup; Morten Kjeldgaard; Brian F C Clark; Jens Nyborg
Purification and crystallization of the ternary complex of elongation factor Tu:GTP and Phe-tRNA(Phe).
FEBS letters 1994;356(2-3):165-8.
1994: Jan Barciszewski; M Sprinzl; Brian F C Clark
Aminoacyl-tRNAs. Diversity before and unity after interaction with EF-Tu:GTP.
FEBS letters 1994;351(1):137-9.
1994: Suresh Rattan; Brian F C Clark
Kinetin delays the onset of ageing characteristics in human fibroblasts.
Biochemical and biophysical research communications 1994;201(2):665-72.
1994: O Wiborg; C Andersen; Charlotte R Knudsen; T J Kristensen; Brian F C Clark
Towards an understanding of structure-function relationships of elongation factor Tu.
Biotechnology and applied biochemistry 1994;19 ( Pt 1)():3-15.
1994: D E Otzen; Jan Barciszewski; Brian F C Clark
Dual hydrolytic role for Pb(II) ions.
Biochimie 1994;76(1):15-21.
1993: D E Otzen; Jan Barciszewski; Brian F C Clark
Altered lead(II)-cleavage pattern of free Phe-tRNAPhe and Phe-tRNAPhe in ternary complex with EF-Tu:GTP.
Biochemistry and molecular biology international 1993;31(1):95-103.
1993: S M Knudsen; Jane Frydenberg; Brian F C Clark; H Leffers
Tissue-dependent variation in the expression of elongation factor-1 alpha isoforms: isolation and characterisation of a cDNA encoding a novel variant of human elongation-factor 1 alpha.
European journal of biochemistry / FEBS 1993;215(3):549-54.
1993: A Derventzi; Suresh Rattan; Brian F C Clark
Phorbol ester PMA stimulates protein synthesis and increases the levels of active elongation factors EF-1 alpha and EF-2 in ageing human fibroblasts.
Mechanisms of ageing and development 1993;69(3):193-205.
1993: Jan Barciszewski; Suresh Rattan; GE Siboska; D E Otzen; Brian F C Clark
Reduction in the amount of 8-hydroxy-2'-deoxyguanosine in the DNA of SV40-transformed human fibroblasts as compared with normal cells in culture.
FEBS letters 1993;318(2):186-8.
1992: Jan Barciszewski; D Otzen; Suresh Rattan; Brian F C Clark
Specific incorporation of kinetin into eukaryotic and prokaryotic transfer ribonucleic acid molecules.
Biochemistry international 1992;28(5):805-11.
1992: Suresh Rattan; A Derventzi; Brian F C Clark
Protein synthesis, posttranslational modifications, and aging.
Annals of the New York Academy of Sciences 1992;663():48-62.
1992: Charlotte R Knudsen; Brian F C Clark; B Degn; O Wiborg
One-step purification of E. coli elongation factor Tu.
Biochemistry international 1992;28(2):353-62.
1992: A Derventzi; Suresh Rattan; Brian F C Clark
Senescent human fibroblasts are more sensitive to the effects of a phorbol ester on macromolecular synthesis and growth characteristics.
Biochemistry international 1992;27(5):903-11.
1992: A Derventzi; Suresh Rattan; Brian F C Clark
Phorbol ester-induced reorganization of the cytoskeleton in human fibroblasts during ageing in vitro.
Biochemical and biophysical research communications 1992;182(3):1423-8.
1991: Suresh Rattan; Walter F Ward; M Glenting; L Svendsen; B Riis; Brian F C Clark
Dietary calorie restriction does not affect the levels of protein elongation factors in rat livers during ageing.
Mechanisms of ageing and development 1991;58(1):85-91.
1991: N J Coppard; Knud Poulsen; H O Madsen; Jane Frydenberg; Brian F C Clark
42Sp48 in previtellogenic Xenopus oocytes is structurally homologous to EF-1 alpha and may be a stage-specific elongation factor.
The Journal of cell biology 1991;112(2):237-43.
1990: B Riis; Suresh Rattan; Brian F C Clark; William C Merrick
Eukaryotic protein elongation factors.
Trends in biochemical sciences 1990;15(11):420-4.
1990: Brian F C Clark; Morten Kjeldgaard; T F la Cour; Søren Thirup; Jens Nyborg
Structural determination of the functional sites of E. coli elongation factor Tu.
Biochimica et biophysica acta 1990;1050(1-3):203-8.
1990: N J Rasmussen; F P Wikman; Brian F C Clark
Crosslinking of tRNA containing a long extra arm to elongation factor Tu by trans-diamminedichloroplatinum(II).
Nucleic acids research 1990;18(16):4883-90.
1990: B Riis; Suresh Rattan; A Derventzi; Brian F C Clark
Reduced levels of ADP-ribosylatable elongation factor-2 in aged and SV40-transformed human cell cultures.
FEBS letters 1990;266(1-2):45-7.
1990: H O Madsen; Knud Poulsen; O Dahl; Brian F C Clark; J Peter Hjorth
Retropseudogenes constitute the major part of the human elongation factor 1 alpha gene family.
Nucleic acids research 1990;18(6):1513-6.
1989: B Riis; Suresh Rattan; Brian F C Clark
Estimating the amounts of ADP-ribosylatable active elongation factor-2 in mammalian cell-free extracts.
Journal of biochemical and biophysical methods 1989;19(4):319-25.
1989: B Riis; Suresh Rattan; J Cavallius; Brian F C Clark
ADP-ribosylatable content of elongation factor-2 changes during cell cycle of normal and cancerous human cells.
Biochemical and biophysical research communications 1989;159(3):1141-6.
1988: Suresh Rattan; J Cavallius; Brian F C Clark
Heat shock-related decline in activity and amounts of active elongation factor 1 alpha in ageing and immortal human cells.
Biochemical and biophysical research communications 1988;152(1):169-76.
1987: Yves Cenatiempo; F Deville; J Dondon; Marianne Grunberg-Manago; Christine Sacerdot; John W B Hershey; H F Hansen; H U Petersen; Brian F C Clark; M Kjeldgaard
The protein synthesis initiation factor 2 G-domain. Study of a functionally active C-terminal 65-kilodalton fragment of IF2 from Escherichia coli.
Biochemistry 1987;26(16):5070-6.
1987: P K Hansen; Brian F C Clark; H U Petersen
Interaction between non-formylated initiator Met-tRNA(fMet) and the ribosomal A-site from Escherichia coli.
Biochimie 1987;69(8):871-7.
1987: Iain W Mattaj; N J Coppard; R S Brown; Brian F C Clark; E M De Robertis
42S p48--the most abundant protein in previtellogenic Xenopus oocytes--resembles elongation factor 1 alpha structurally and functionally.
The EMBO journal 1987;6(8):2409-13.
1987: F P Wikman; Pascale Romby; M H Metz; J Reinbolt; Brian F C Clark; J P Ebel; C Ehresmann; B Ehresmann
Crosslinking of elongation factor Tu to tRNA(Phe) by trans-diamminedichloroplatinum (II). Characterization of two crosslinking sites in the tRNA.
Nucleic acids research 1987;15(14):5787-801.
1986: P K Hansen; F Wikman; Brian F C Clark; J W Hershey; H Uffe Petersen
Interaction between initiator Met-tRNAfMet and elongation factor EF-Tu from E. coli.
Biochimie 1986;68(5):697-703.
1986: J Cavallius; Suresh Rattan; Brian F C Clark
Changes in activity and amount of active elongation factor 1 alpha in aging and immortal human fibroblast cultures.
Experimental gerontology 1986;21(3):149-57.
1985: T Jørgensen; GE Siboska; F P Wikman; Brian F C Clark
Different conformations of tRNA in the ribosomal P-site and A-site.
European journal of biochemistry / FEBS 1985;153(1):203-9.
1985: F McCormick; Brian F C Clark; T F la Cour; Morten Kjeldgaard; Leif Norskov; Jens Nyborg
A model for the tertiary structure of p21, the product of the ras oncogene.
Science (New York, N.Y.) 1985;230(4721):78-82.
1985: T F la Cour; Jens Nyborg; Søren Thirup; Brian F C Clark
Structural details of the binding of guanosine diphosphate to elongation factor Tu from E. coli as studied by X-ray crystallography.
The EMBO journal 1985;4(9):2385-8.
1984: H U Petersen; GE Siboska; Brian F C Clark; Richard Buckingham; C Hountondji; S Blanquet
Interaction between dimeric methionyl-tRNA synthetase and methionine accepting tRNAs from E. coli.-- Studies by partial ribonuclease digestion.
Biochimie 1984;66(9-10):625-30.
1984: J M Van Noort; Barend Kraal; L Bosch; T F La Cour; Jens Nyborg; Brian F C Clark
Cross-linking of tRNA at two different sites of the elongation factor Tu.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(13):3969-72.
1984: F J Duisterwinkel; Barend Kraal; J M De Graaf; A Talens; L Bosch; G W Swart; Andrea Parmeggiani; T F La Cour; Jens Nyborg; Brian F C Clark
Specific alterations of the EF-Tu polypeptide chain considered in the light of its three-dimensional structure.
The EMBO journal 1984;3(1):113-20.
1983: N J Coppard; Brian F C Clark; F Cramer
Methylation of elongation factor 1 alpha in mouse 3T3B and 3T3B/SV40 cells.
FEBS letters 1983;164(2):330-4.
1982: N J Coppard; F Cramer; Brian F C Clark
Identification of elongation factor 1 alpha from mouse liver.
FEBS letters 1982;145(2):332-6.
1982: T A Kruse; GE Siboska; Brian F C Clark
Photosensitized crosslinking of tRNA to the P-, A- and R-sites of Escherichia coli ribosomes.
Biochimie 1982;64(4):279-84.
1982: Brian F C Clark; T F la Cour; J Fontecilla-Camps; K Morikawa; K M Nielsen; Jens Nyborg; J R Rubin
Three dimensional structural elements of bacterial elongation factor Tu complexed with GDP.
Progress in clinical and biological research 1982;102 Pt C():59-64.
1982: F P Wikman; GE Siboska; H U Petersen; Brian F C Clark
The site of interaction of aminoacyl-tRNA with elongation factor Tu.
The EMBO journal 1982;1(9):1095-100.
1981: A S Boutorin; Brian F C Clark; J P Ebel; T A Kruse; H U Petersen; P Remy; S Vassilenko
A study of the interaction of Escherichia coli elongation factor-Tu with aminoacyl-tRNAs by partial digestion with cobra venom ribonuclease.
Journal of molecular biology 1981;152(3):593-608.
1981: J R Rubin; K Morikawa; Jens Nyborg; T F la Cour; Brian F C Clark; D L Miller
Structural features of the GDP binding site of elongation factor Tu from Escherichia coli as determined by x-ray diffraction.
FEBS letters 1981;129(1):177-9.
1981: H U Petersen; T A Kruse; H Worm-Leonhard; GE Siboska; Brian F C Clark; A S Boutorin; P Remy; J P Ebel; J Dondon; Marianne Grunberg-Manago
Study of the interaction of Escherichia coli initiation factor IF2 with formylmethionyl-tRNAMetf by partial digestion with cobra venom ribonuclease.
FEBS letters 1981;128(1):161-5.
1980: M D Jones; T E Petersen; K M Nielsen; S Magnusson; L Sottrup-Jensen; K Gausing; Brian F C Clark
The complete amino-acid sequence of elongation factor Tu from Escherichia coli.
European journal of biochemistry / FEBS 1980;108(2):507-26.
1980: K Arai; Brian F C Clark; L Duffy; M D Jones; Y Kaziro; R A Laursen; J L'Italien; D L Miller; S Nagarkatti; S Nakamura; K M Nielsen; T E Petersen; K Takahashi; M Wade
Primary structure of elongation factor Tu from Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(3):1326-30.
1980: T A Kruse; GE Siboska; M Sprinzl; Brian F C Clark
The effect of chemical modification of the CCA end of yeast tRNAPhe on its biological activity on ribosomes.
European journal of biochemistry / FEBS 1980;107(1):1-6.